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Journal articles on the topic 'DCC 9'

Author: Grafiati

Published: 4 June 2021

Last updated: 10 February 2022

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1

Miyake, K., K. Inokuchi, K. Dan, and T. Nomura. "Alterations in the deleted in colorectal carcinoma gene in human primary leukemia." Blood 82, no. 3 (1993): 927–30. http://dx.doi.org/10.1182/blood.v82.3.927.927.

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Abstract To evaluate the role of the deleted in colorectal carcinoma (DCC) gene in leukemogenesis, we examined loss of heterozygosity (LOH) in the DCC gene in 64 primary human leukemias using Southern blot analysis and examined the expression of the DCC gene using reverse transcriptase- polymerase chain reaction (RT-PCR) analysis. Allelic loss in the DCC gene was observed in two patients (6%, 2 of 35 informative cases), and expression of the DCC gene was reduced or absent in 8 of 26 (31%) patients with acute myelogenous leukemia (AML), 3 of 9 (33%) patients with acute lymphocytic leukemia (ALL

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2

Miyake, K., K. Inokuchi, K. Dan, and T. Nomura. "Alterations in the deleted in colorectal carcinoma gene in human primary leukemia." Blood 82, no. 3 (1993): 927–30. http://dx.doi.org/10.1182/blood.v82.3.927.bloodjournal823927.

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To evaluate the role of the deleted in colorectal carcinoma (DCC) gene in leukemogenesis, we examined loss of heterozygosity (LOH) in the DCC gene in 64 primary human leukemias using Southern blot analysis and examined the expression of the DCC gene using reverse transcriptase- polymerase chain reaction (RT-PCR) analysis. Allelic loss in the DCC gene was observed in two patients (6%, 2 of 35 informative cases), and expression of the DCC gene was reduced or absent in 8 of 26 (31%) patients with acute myelogenous leukemia (AML), 3 of 9 (33%) patients with acute lymphocytic leukemia (ALL), and 7

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3

Inokuchi, Koiti, Mituharu Inami, Yazhu Wang, et al. "The DCC Heterozygote Reduces the Latency Period and Changes the Disease Phenotype of Myeloproliferative Disease in p230BCR/ABL-Expressing Mice." Blood 104, no. 11 (2004): 2968. http://dx.doi.org/10.1182/blood.v104.11.2968.2968.

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Abstract Chronic neutrophilic leukemia (CNL) is a distinct disease form with less aggressive phenotype mimicking chronic myelogenous leukemia (CML). CNL sometimes has a unique p230BCR/ABL gene abnormality, as does Philadelphia-positive myeloproliferative disease (MPD) mimicking essential thrombocythemia (Ph+ET). The reason of the phenotypic difference between CNL and Ph+ET remains unclear. Recently, we have generated the p230BCR/ABL-transgenic mice, whose disease phenotype is MPD mimicking ET, to study the disease phenotype. In studies of human leukemia cells, loss of DCC (deleted colorectal c

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4

Younes, A., S. Zhao, D. Jendiroba, HD Kleine, F. Cabanillas, and M. Andreeff. "Decreased expression of the deleted in colorectal carcinoma gene in non- Hodgkin's lymphoma." Blood 85, no. 10 (1995): 2813–16. http://dx.doi.org/10.1182/blood.v85.10.2813.bloodjournal85102813.

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The putative tumor suppressor gene deleted in colorectal carcinoma (DCC), located on human chromosome band 18q21, is deleted or inactivated in many solid tumors. Its role in the pathogenesis of non- Hodgkin's lymphoma (NHL) has not been studied. Recently, inactivation of this gene was reported in cases of leukemia with monosomy 18. As monosomy 18 is frequently observed in low-grade NHL, we investigated the incidence of altered DCC gene expression in patients with NHL, and correlated it with the number of copies of chromosome 18. Fifteen unselected cases of NHL were studied for evidence of DCC

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5

Nagoshi, Hisao, Tomohiko Taki, Kazuhiro Nishida, et al. "Alterations of DCC Gene in B-Cell Malignancies." Blood 114, no. 22 (2009): 4428. http://dx.doi.org/10.1182/blood.v114.22.4428.4428.

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Abstract Abstract 4428 Many genetic alterations have been detected in various tumors to date, and these are concerned with oncogenesis closely. Oligonucleotide array analysis has contributed to detect genomic gains and losses implicated in the development of human malignant tumors, identifying either oncogenes or tumor suppressor genes. In our recent data, oligonucleotide array analysis showed recurrent genomic copy number variations at 18q21-22 in malignant lymphoma and multiple myeloma cell lines. There are a lot of genes related to oncogenesis at 18q21-22, such as SMAD4, DCC, MBD2, TCF4, TX

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6

Plooster, Melissa, Shalini Menon, Cortney C. Winkle, et al. "TRIM9-dependent ubiquitination of DCC constrains kinase signaling, exocytosis, and axon branching." Molecular Biology of the Cell 28, no. 18 (2017): 2374–85. http://dx.doi.org/10.1091/mbc.e16-08-0594.

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Extracellular netrin-1 and its receptor deleted in colorectal cancer (DCC) promote axon branching in developing cortical neurons. Netrin-dependent morphogenesis is preceded by multimerization of DCC, activation of FAK and Src family kinases, and increases in exocytic vesicle fusion, yet how these occurrences are linked is unknown. Here we demonstrate that tripartite motif protein 9 (TRIM9)-dependent ubiquitination of DCC blocks the interaction with and phosphorylation of FAK. Upon netrin-1 stimulation TRIM9 promotes DCC multimerization, but TRIM9-dependent ubiquitination of DCC is reduced, whi

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7

Rosenow, Felix, Gerda Silling, Berkemeier Almut, et al. "Immunological Intervention Triggered by Decreasing CD34 + Lineage-Specific Donor Cell Chimerism to Prevent Relapse of Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)." Blood 114, no. 22 (2009): 3317. http://dx.doi.org/10.1182/blood.v114.22.3317.3317.

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Abstract Abstract 3317 Poster Board III-205 Relapse of the underlying malignant disease remains the most frequent cause of treatment failure in patients with AML or MDS after allogeneic HSCT. Analysis of CD34+ lineage-specific donor cell chimerism (DCC) is a sensitive method for monitoring of minimal residual disease (MRD) in patients with AML or MDS with CD34 expression. Early detection of increasing MRD in this group of transplanted patients may provide an indication for clinical interventions as it has been shown for patients with chronic myeloid leukemia. Therefore, we retrospectively addr

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8

Nagoshi, Hisao, Tomohiko Taki, Junya Kuroda, et al. "Identification and Functional Significance of Novel Type of Structurally Aberrant Transcripts of DCC In B-Cell Malignancies." Blood 116, no. 21 (2010): 3623. http://dx.doi.org/10.1182/blood.v116.21.3623.3623.

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Abstract Abstract 3623 Many genetic alterations have been detected in various tumors, and their expression levels have also been investigated concerning cancer development or progression. Gene expressions have so far been examined by Northern blotting, reverse-transcriptase-polymerase chain reaction (RT-PCR), microarray and real-time PCR. There are several papers reporting that the expression level of genes, such as EVI1 and BAALC, are associated with clinical outcome in some types of hematologic malignancies, however, we do not know whether the genes detected are structurally normal or abnorm

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9

Li, Yang, Zhendi Wang, and Ling Wang. "Maleic Rosin-based Gemini Surfactant as Air Entraining Agent for Concrete under Low Air Pressure." Revista de Chimie 72, no. 2 (2021): 27–37. http://dx.doi.org/10.37358/rc.21.2.8417.

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The effectiveness of Air entraining agent (AEA) in concrete under low air pressure in the plateau area decreased. A type of new AEA, named MRE was synthesized to increase bubbles` stability in fresh concrete under low air pressure. The performance of MRE solution and concrete with MRE were tested under 60 kPa and 100 kPa compared with commercially gemini AEA (DCC). The test results showed that the foam volume of MRE and DCC solution under 60 kPa was reduced by 3% and 9% than under 100 kPa. The bubble liquid film strength of MRE is 63% higher than that of DCC. For concrete with MRE and DCC unde

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10

Rahman, Kazi Mizanur, Yushuf Sharker, Reza Ali Rumi, et al. "An Association between Rainy Days with Clinical Dengue Fever in Dhaka, Bangladesh: Findings from a Hospital Based Study." International Journal of Environmental Research and Public Health 17, no. 24 (2020): 9506. http://dx.doi.org/10.3390/ijerph17249506.

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Background: Dengue, a febrile illness, is caused by a Flavivirus transmitted by Aedes aegypti and Aedes albopictus mosquitoes. Climate influences the ecology of the vectors. We aimed to identify the influence of climatic variability on the occurrence of clinical dengue requiring hospitalization in Zone-5, a high incidence area of Dhaka City Corporation (DCC), Bangladesh. Methods and Findings: We retrospectively identified clinical dengue cases hospitalized from Zone-5 of DCC between 2005 and 2009. We extracted records of the four major catchment hospitals of the study area. The Bangladesh Mete

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11

Widyastuti, Siti Budiati, Soedjatmiko Soedjatmiko, and Agus Firmansyah. "Growth and development profile of children at two day care centers in Jakarta." Paediatrica Indonesiana 45, no. 6 (2016): 275. http://dx.doi.org/10.14238/pi45.6.2005.275-9.

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Background Working mothers with toddlers are often confusedwith the difficulties of caregiver substitutes. This leads to the con-cern about neglecting their toddlers. Day care centers are expectedto respond by substituting the absent mothers, in order for thechildren’s needs of growth and development to become optimal.Objective To examine the profile of day care centers in correla-tion with growth and development of toddlers, and to understandthe characteristics of facilities for growth and development in tod-dlers at day care centers.Method This cross-sectional study was conducted at the day

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12

Bellali, Thalia, Georgios Manomenidis, Charalampos Platis, Eleni Kourtidou, and Petros Galanis. "Factors Associated With Emergency Department Health Professionals' Attitudes Toward Family Presence During Adult Resuscitation in 9 Greek Hospitals." Dimensions of Critical Care Nursing 39, no. 5 (2020): 269–77. http://dx.doi.org/10.1097/dcc.0000000000000417.

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13

Castro, Davi Elias De Sá e., Paulo Levi De Oliveira Carvalho, Newton Tavares Escocard de Oliveira, et al. "Dehydrated cassava co-product in starting piglets feeding." Semina: Ciências Agrárias 38, no. 4Supl1 (2017): 2775. http://dx.doi.org/10.5433/1679-0359.2017v38n4supl1p2775.

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Two experiments were carried out to determine the nutritional value of a dehydrated cassava co-product (DCC) and its effects on the performance and blood variables of piglets fed with different levels of DCC. In experiment I, a digestibility assay was performed and 30 whole-male crossbred piglets with initial body weight of 18.00 ± 0.673 kg were housed individually in metabolism cages and distributed in a completely randomized experimental design with 5 treatments, 6 replicates and one animal per experimental unit. A reference diet was formulated to meet the category nutritional requirements a

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14

Castro, Davi Elias De Sá e., Paulo Levi De Oliveira Carvalho, Newton Tavares Escocard de Oliveira, et al. "Dehydrated cassava co-product in starting piglets feeding." Semina: Ciências Agrárias 38, no. 4Supl1 (2017): 2775. http://dx.doi.org/10.5433/1679-0359.2017v38n4suplp2775.

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Two experiments were carried out to determine the nutritional value of a dehydrated cassava co-product (DCC) and its effects on the performance and blood variables of piglets fed with different levels of DCC. In experiment I, a digestibility assay was performed and 30 whole-male crossbred piglets with initial body weight of 18.00 ± 0.673 kg were housed individually in metabolism cages and distributed in a completely randomized experimental design with 5 treatments, 6 replicates and one animal per experimental unit. A reference diet was formulated to meet the category nutritional requirements a

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15

Lendvai, Gábor, Tímea Szekerczés, Ildikó Illyés, et al. "Autophagy activity in cholangiocarcinoma is associated with anatomical localization of the tumor." PLOS ONE 16, no. 6 (2021): e0253065. http://dx.doi.org/10.1371/journal.pone.0253065.

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The presence of autophagy has been indicated in cholangiocarcinoma (CC), which disease has poor prognosis and limited treatment options. Recently, CC has been classified by anatomical localization as intrahepatic (iCC), perihilar (pCC) and distal (dCC), showing different clinical and molecular characteristics. Thus, our aim was to compare autophagy activity in CC samples resected from different anatomical locations. Further, we investigated whether autophagy could be modulated in cell lines originated from iCC and extrahepatic CC (eCC) following the treatments with autophagy inhibitory and ind

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16

Grzeszczuk, Piotr, and Edmund R. Puczyłowski. "Goldie Dimension and Chain Conditions for Modular Lattices with Finite Group Actions." Canadian Mathematical Bulletin 29, no. 3 (1986): 274–80. http://dx.doi.org/10.4153/cmb-1986-042-9.

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AbstractA relation between Goldie dimensions of a modular lattice L and its sublattice LG of fixed points under a finite group G of automorphisms of L is obtained. The method used also gives a relation between ACC (DCC) for L and for LG. The results obtained are applied to rings and modules.

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17

Javidiar, Arsya, and Irwan Adi Ekaputra. "The Dynamics of Exchange Rate and Stock Return Before and After the Fed Policy Normalization: Evidence from Fragile Five Countries." International Journal of Business Studies 3, no. 2 (2019): 54–63. http://dx.doi.org/10.32924/ijbs.v3i2.63.

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Abstract: This research aims to examine the correlation between exchange rate and stock price return in each fragile five countries; Indonesia, Brazil, India, Turkey and South Africa. Using daily data, we investigate and then divide it into two periods; before Fed funds rate normalization (2013-2015) and after normalization (2016-2018), to find out whether the Fed funds rate hike caused a difference in the correlation between the two variables in each fragile five country. The methods used for this analysis are granger causality test and Vector Autoregression (VAR) using Eviews 9 program. Furt

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18

Mediero, Aránzazu, Amitabha Mazumder, and Bruce Cronstein. "Netrin-1 and Its Receptors Unc5b and DCC May be Useful Targets for Preventing Multiple Myeloma Bone Lesions." Blood 126, no. 23 (2015): 1815. http://dx.doi.org/10.1182/blood.v126.23.1815.1815.

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Abstract Purpose: Multiple Myeloma is a hematologic malignancy that involves the malignant proliferation of plasma cells. This type of malignancy is particularly trophic to bone where it induces osteoclastic destruction of bone. We have recently demonstrated that osteoclast differentiation is dependent upon the autocrine/paracrine expression of the laminin-like matrix protein and chemorepulsant netrin1 and binding of netrin1 to the receptor unc5b. We therefore asked whether targeting netrin1 and its receptors unc5b and DCC could regulate myeloma spread in a murine model of myeloma. Methods: 10

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19

Wada, C., S. Shionoya, Y. Fujino, et al. "Genomic instability of microsatellite repeats and its association with the evolution of chronic myelogenous leukemia [see comments]." Blood 83, no. 12 (1994): 3449–56. http://dx.doi.org/10.1182/blood.v83.12.3449.3449.

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Abstract Tumorigenesis has been shown to proceed through a series of genetic alterations involving protooncogenes and tumor-suppressor genes. Investigation of genomic instability of microsatellites has indicated a new mechanism for human carcinogenesis in hereditary nonpolyposis colorectal cancer and sporadic cancer and this instability has been shown to be related to inherited predisposition to cancer. This study was conducted to determine whether such microsatellite instability is associated with the evolution of chronic myelogenous leukemia (CML) to the blast crisis. Nineteen CML patients c

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Wada, C., S. Shionoya, Y. Fujino, et al. "Genomic instability of microsatellite repeats and its association with the evolution of chronic myelogenous leukemia [see comments]." Blood 83, no. 12 (1994): 3449–56. http://dx.doi.org/10.1182/blood.v83.12.3449.bloodjournal83123449.

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Tumorigenesis has been shown to proceed through a series of genetic alterations involving protooncogenes and tumor-suppressor genes. Investigation of genomic instability of microsatellites has indicated a new mechanism for human carcinogenesis in hereditary nonpolyposis colorectal cancer and sporadic cancer and this instability has been shown to be related to inherited predisposition to cancer. This study was conducted to determine whether such microsatellite instability is associated with the evolution of chronic myelogenous leukemia (CML) to the blast crisis. Nineteen CML patients clinically

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21

Nobusawa, R., N. Aoyama, Y. Honsako, et al. "DCC gene codon 201Gly is associated with flat type colorectal tumor." Gastroenterology 108, no. 4 (1995): A516. http://dx.doi.org/10.1016/0016-5085(95)26379-9.

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22

Li, Xuedi, Jie Ma, Zhu Chen, and Haitao Zheng. "Linkage Analysis among China’s Seven Emissions Trading Scheme Pilots." Sustainability 10, no. 10 (2018): 3389. http://dx.doi.org/10.3390/su10103389.

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This paper focuses on the time-varying correlation among China’s seven emissions trading scheme markets. Correlation analysis shows a weak connection among these markets for the whole sample period, which spans from 9 June 2014 to 30 June 2017. The return rate series of the seven markets show the characteristics of a fat-tailed and skewed distribution, and the Vector Autoregression (VAR) residuals present a significant Autoregressive Conditional Heteroscedasticity (ARCH) effect. Therefore, we adopt Vector Autoregression Generalized ARCH model with Dynamic Conditional Correlation (VAR-DCC-GARCH

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23

Torres-Vega, Estefanía, Nuria Mancheño, Arantxa Cebrián-Silla, et al. "Netrin-1 receptor antibodies in thymoma-associated neuromyotonia with myasthenia gravis." Neurology 88, no. 13 (2017): 1235–42. http://dx.doi.org/10.1212/wnl.0000000000003778.

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Objective:To identify cell-surface antibodies in patients with neuromyotonia and to describe the main clinical implications.Methods:Sera of 3 patients with thymoma-associated neuromyotonia and myasthenia gravis were used to immunoprecipitate and characterize neuronal cell-surface antigens using reported techniques. The clinical significance of antibodies against precipitated proteins was assessed with sera of 98 patients (neuromyotonia 46, myasthenia gravis 52, thymoma 42; 33 of them with overlapping syndromes) and 219 controls (other neurologic diseases, cancer, and healthy volunteers).Result

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24

Todorova, Daniela, Maria Tupova, Veneta Zapreva, Tsenka Milkova, and Atanas Kujumdjiev. "Transformation of Aminosteroids into Pharmacologically Active Amides of Phenolic Acids." Zeitschrift für Naturforschung C 54, no. 1-2 (1999): 65–69. http://dx.doi.org/10.1515/znc-1999-1-212.

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Amides of cinnamic acid derivatives with 3α-and 3β-cholestanylamines, as well as with 3α-and 3β-amino-(2’-aminoethyl)-cholest-5-en were synthesized using dicyclohexylcarbodiimide (DCC) and 1-hydroxy-benzotriazole as efficient additives. Their structure was determined by UV and 1HNMR . 3β-Amino-(2’-aminoethyl)-cholest-5-en, amides of p-hydroxy-cinnamic acid 4 and 9, and N-cholest-5-en-3α-aminoethyl-di-(3’’,-phenyl-trans-2’’-propene)-amide 10 showed moderate antibacterial activity against Staphylococcus aureus

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Cavalieri, Stefano, Anastasios Stathis, Alessandra Fabbri, et al. "Uncommon Somatic Mutations in Metastatic NUT Midline Carcinoma." Tumori Journal 103, no. 1_suppl (2017): S5—S8. http://dx.doi.org/10.5301/tj.5000685.

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Introduction NUT midline carcinoma (NMC) is a rare and aggressive epithelial cancer arising from median organs. It is driven by chromosomal translocation t(15;19) involving the rearrangement of NUT (nuclear protein in testis) and BRD4 (bromodomain 4) genes leading to fusion oncoprotein BRD4-NUT. Case presentation We report the case of a woman who was previously treated with induction chemotherapy, surgery, radiotherapy and adjuvant trastuzumab for HER-2 positive invasive ductal carcinoma of the breast. After 6 months of follow-up a lung nodule appeared. A biopsy showed an adenocarcinoma fetal

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26

Nissenkorn, Andreea, Keren Yosovich, Zvi Leibovitz, et al. "Congenital Mirror Movements Associated With Brain Malformations." Journal of Child Neurology 36, no. 7 (2021): 545–55. http://dx.doi.org/10.1177/0883073820984068.

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Background: Congenital mirror movements are involuntary movements of a side of the body imitating intentional movements on the opposite side, appearing in early childhood and persisting beyond 7 years of age. Congenital mirror movements are usually idiopathic but have been reported in association with various brain malformations. Methods: We describe clinical, genetic, and radiologic features in 9 individuals from 5 families manifesting congenital mirror movements. Results: The brain malformations associated with congenital mirror movements were: dysplastic corpus callosum in father and daught

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27

Ronchi, Enrico, Giovanna Granata, Moreno Brivio, Danila Coradini, Patrizia Miodini, and Giovanni Di Fronzo. "A Double-Labeling Assay for Simultaneous Estimation and Characterization of Estrogen and Progesterone Receptors using Radioiodinated Estradiol and Tritiated Org 2058." Tumori Journal 72, no. 3 (1986): 251–57. http://dx.doi.org/10.1177/030089168607200305.

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Estrogen (ER) and progesterone receptors (PgR) appear to be a prerequisite to elicit a biologic response by a hormone-target organ. Current methodologies for analysis of these proteins (e.g., dextran-coated charcoal, DCC) in single-label assay (SLA) require relatively large amounts of tissue material, time and laboriousness. Therefore, we have developed for breast cancer tissue an improved dual-label assay (DLA) for simultaneous titration (by DCC) and/or characterization (by sedimentation properties) of ER and PgR on the same sample, using 125I-E2 and 3H-Org 2058 as tracers. The interaction of

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28

Zia, Mehwash, Tashfeen Akhtar, Shahid Hameed, and Najim A. Al-Masoudi. "New Aryl-1,3-thiazole-4-carbohydrazides, Their 1,3,4-Oxadiazole-2- thione, 1,2,4-Triazole, Isatin-3-ylidene and Carboxamide Derivatives. Synthesis and Anti-HIV Activity." Zeitschrift für Naturforschung B 67, no. 7 (2012): 747–58. http://dx.doi.org/10.5560/znb.2012-0095.

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A series of isatin-3-ylidene (6a-i) and arylthiazolyl-1,3,4-oxadiazole-2-thione derivatives 7a-i derived from arylthiazolyl carbohydrazide analogs 4a-i were synthesized. Analogously, coupling of 4f with various amino acid methyl esters in the presence of HOBt/DCC reagents afforded the carboxamide derivatives 9a-d. The newly synthesized compounds were assayed against HIV-1 and HIV-2 in MT-4 cells. All compounds are inactive, except compounds 9b and 9c which showed inhibition of HIV-1 with EC50 = 2:34 μg mL-1, and 1.12 μg mL-1 with therapeutic indexes (SI) of 9 and <1, respectively.

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29

Himbert, Gerhard, and Dieter Fink. "Cycloadditionen, XXII [1]. Synthese und thermische Reaktion von S-(Alkyl/Aryl)- 2.3-butadienthiosäure-estern / Cycloadditions, XXII [1]. Synthesis and Thermal Reaction of S-(Alkyl/Aryl)-2,3-butadienethioates." Zeitschrift für Naturforschung B 49, no. 4 (1994): 542–50. http://dx.doi.org/10.1515/znb-1994-0417.

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While the S-alkyl- or S-phenyl-2,3-butadienethioates 4 a-c are synthesized via the usual “Wittig ylide way”, the corresponding 2-methyl-2,3-butadienethioates 9 a-d and the 2-methyl-4.4-diphenyl-2,3-butadienethioates 9 e,f are obtained by condensation of the allenic acids 7 a,b with the thiols and thiophenols 8 in the presence of dicyclohexylcarbodiimide (DCC) and a catalytic am ount of 4-dimethylaminopyridine (DMAP). In contrast to N- or O-phenyl 2,3- butadienamides or -esters, resp., the phenyl derivatives of 4 and 9 do not undergo the intram olecular Diels-Alder reaction, but by heating, all

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30

Cid, Juan-José, Jan Duchateau, Ineke Van Severen, et al. "Synthesis and characterization of high molecular weight phthalocyanine-PPV copolymers through post-polymerization functionalization." Journal of Porphyrins and Phthalocyanines 15, no. 07n08 (2011): 659–66. http://dx.doi.org/10.1142/s1088424611003562.

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High molecular weight poly(p-phenylenenevinylene) PPV copolymers laterally substituted with zinc (II) phthalocyanines ( Zn(II)Pc -PPV 1 and 2) have been synthesized by means of post-polymerization functionalization reactions through DCC-mediated esterifications between hydroxy-phthalocyanines 4 and 6 and carboxy-bearer PPV copolymers, comprising 2-methoxy-5-(3,7-dimethyloctyloxy)-1,4-phenylenevinylene (MDMO-PPV) and 1,4-(2-(5-carboxypentyloxy)-5-methoxyphenylenevinylene (CPM-PPV) units in a 9:1 (3) and 1:1 (5) ratio, respectively. The resulting copolymer 1 contains a 7 mol % of Pc molecules, w

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31

Nasirtabrizi, Mohammad Hossein, L. Zargin, S. Khodabandlou, and S. Rostamzadeh Mansour. "Functionalization and Chemical Modification of 2-Hydroxyethyl Methacrylate with Carboxylic Acid." E-Journal of Chemistry 9, no. 3 (2012): 1135–44. http://dx.doi.org/10.1155/2012/603573.

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Free radical polymerization of the resulting monomers methyl methacrylate (MMA), ethyl methacrylate (EMA), methylacrylate (MA) and ethylacrylate (EA) with 2-hydroxyethyl methacrylate (HEMA) (in 1:1 mole ratio) were carried out using azobis(isoboutyronitrile) (AIBN) as initiator at the temperature ranges 60-70°C. The modification of polymers were carried out by 9-anthracenecarboxylic acid (9-ACA) via the esterification reaction between —OH of poly(HEMA) and —COOH of 9-ACA, in presence of N,N′-dicyclohexyl-carbodiimide (DCC), 4-(dimethylamino) pyridine (DMAP) and N,N-dimethyl formamid (DMF). It

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32

Ito, Hiromichi, Yoshihiro Ono, Takafumi Sato, Yosuke Inoue, and Yu Takahashi. "Role of para-aortic lymph node sampling for patients with potentially resectable biliary cancer." Journal of Clinical Oncology 38, no. 4_suppl (2020): 540. http://dx.doi.org/10.1200/jco.2020.38.4_suppl.540.

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540 Background: While paraaortic lymph node (PALN) metastasis has been known as poor prognostic indicator for patients with biliary cancer and is regarded as distant metastasis in AJCC staging system. However, preoperative diagnosis of PALN metastasis by current imaging studies is not accurate and the incidence of PALN metastasis among patients with potentially resectable biliary cancer and its impact on their long-term outcomes remain unclear. Methods: The patients who underwent exploratory laparotomy with PALN sampling for potentially resectable biliary cancer at our institution from 2006 th

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33

Himbert, Gerhard, Dieter Fink, and Martina Stürm. "Cycloadditionen, XXI [1]. 2-Methyl-2,3-butadiensäure-arylester; Synthese und thermische Reaktivität / Cycloadditions, XXI [1] Aryl 2-methyl-2,3-butadienoates; Synthesis and Thermal Reactivity." Zeitschrift für Naturforschung B 49, no. 1 (1994): 63–75. http://dx.doi.org/10.1515/znb-1994-0114.

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Abstract The substituted phenyl, 1-naphthyl or the 9-anthrylmethyl esters of the 2-methyl-(or 2-phenyl)-2,3-alkadienoic acids (see 4 a -g , 9 a -d and 12a,b) are synthesized by condensation of the allenic acids 2 a -d with the substituted phenols 3 a -g , with 1-naphthol (8) or with 9-anthrylmethanol (11) in the presence of dicyclohexyl carbodiimide (DCC) and a catalytic amount of 4-dimethylaminopyridine (DMAP). An alternative route is the reaction of the acid chloride la with the phenols 3 a -c (see formation of 4 a -c) in the presence of triethylamine. All these compounds (except 12a) underg

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Fares, Rafaelle Christine Gomes, Juliana de Assis Silva Gomes, Luciana Ribeiro Garzoni, et al. "Matrix Metalloproteinases 2 and 9 Are Differentially Expressed in Patients with Indeterminate and Cardiac Clinical Forms of Chagas Disease." Infection and Immunity 81, no. 10 (2013): 3600–3608. http://dx.doi.org/10.1128/iai.00153-13.

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ABSTRACTDilated chronic cardiomyopathy (DCC) from Chagas disease is associated with myocardial remodeling and interstitial fibrosis, resulting in extracellular matrix (ECM) changes. In this study, we characterized for the first time the serum matrix metalloproteinase 2 (MMP-2) and MMP-9 levels, as well as their main cell sources in peripheral blood mononuclear cells from patients presenting with the indeterminate (IND) or cardiac (CARD) clinical form of Chagas disease. Our results showed that serum levels of MMP-9 are associated with the severity of Chagas disease. The analysis of MMP producti

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35

Al-Soud, Yaseen A., Najim A. Al-Masoudi, Hossam H. Al-Suod, and Christophe Pannecouque. "Nitroimidazoles Part 8. Synthesis and Anti-HIV Activity of New 4-Nitroimidazole Derivatives Using the Suzuki Cross-Coupling Reaction." Zeitschrift für Naturforschung B 67, no. 9 (2012): 925–34. http://dx.doi.org/10.5560/znb.2012-0185.

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The development of new HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs) offers the possibility of generating structures of increased potency. To this end, a series of 1-(1-benzyl-2-ethyl- 4-nitro-1H-imidazol-5-yl)-4-(1,1'-biaryl)-4-yl-piperazine derivatives (6a-l) was synthesized via the Suzuki coupling reaction. Analogously, coupling of the acid derivative 5, prepared from 4, with various amino acid methyl esters in the presence of HOBt/DCC reagents afforded the benzamide derivatives 8-11. The newly synthesized compounds were assayed against HIV-1 and HIV-2 in MT- 4 cells. All com

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Wang, Xinghui, Qianqian Chen, Sheng Yi, et al. "The microRNAs let-7 and miR-9 down-regulate the axon-guidance genes Ntn1 and Dcc during peripheral nerve regeneration." Journal of Biological Chemistry 294, no. 10 (2019): 3489–500. http://dx.doi.org/10.1074/jbc.ra119.007389.

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Willhuber, Gaston Camino, Joaquin Stagnaro, Matias Petracchi, et al. "Short-term complication rate following orthopedic surgery in a tertiary care center in Argentina." SICOT-J 4 (2018): 26. http://dx.doi.org/10.1051/sicotj/2018027.

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Introduction: Registration of adverse events following orthopedic surgery has a critical role in patient safety and has received increasing attention. The purpose of this study was to determine the prevalence and severity of postoperative complications in the department of orthopedic unit in a tertiary hospital. Methods: A retrospective review from the postoperative complication registry of a cohort of consecutive patients operated in the department of orthopedic surgery from May 2015 to June 2016 was performed. Short-term complications (3 months after surgery), age gender, types of surgery (e

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Csekö, József, H. Olga Hankovszky, and Kálmán Hideg. "Synthesis of novel, highly reactive 1-oxyl-2,2,6,6-tetramethyl-1,2,5,6-tetrahydropyridine derivatives." Canadian Journal of Chemistry 63, no. 4 (1985): 940–43. http://dx.doi.org/10.1139/v85-156.

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New multipurpose spin labels and synthons can be synthesized from 1-oxyl-2,2,6,6-tetramethyl-1,2,5,6-tetrahydropyridine-4-carboxylic acid (1). Either 1, its pentafluorophenylester (2), or acylcarbonate (3) (prepared from 1 with ethyl chloroformate) can be reduced to 1-oxyl-2,2,6,6-tetramethyl-4-hydroxymethyl-1,2,5,6-tetrahydropyridine (4). The methanesulfonate (6) and the bromo compound (7) are highly reactive alkylating reagents due, in large part, to the allylic linkage in the nitroxide ring. The latter can be reacted with KSSO2CH3 to give methanethiolsulfonate (9). A novel side chain spin-l

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SHAHRUKH, HINA, IMRAN ABBAS JADOON, and RAHEEL MUMTAZ. "An Investigation into Dynamic Conditional Correlation of Pakistan Stock Market with its Trade Partners â€“ Under Covid-19 Perspective." International Review of Management and Business Research 10, no. 1 (2021): 100–118. http://dx.doi.org/10.30543/10-1(2021)-9.

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This study investigates the financial linkage of Pakistan stock market with those of its three major trade partners i.e., China, UK and USA and the impact of ongoing global health crisis (Covid-19) on this linkage. A Dynamic Conditional Generalized Autoregressive Conditional Heteroscedasticity (DCC-GARCH) approach was used to calculate dynamic correlation coefficient between the countries’ stock markets by using the daily price data of MSCI indices spanning the period 1st January 2016 to 31 December 2019 (Pre COVID-19 period) and 1st January 2020 to 30th June 2020 (COVID-19 period). The empiri

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Wang, Xinghui, Qianqian Chen, Sheng Yi, et al. "Correction: The microRNAs let-7 and miR-9 down-regulate the axon-guidance genes Ntn1 and Dcc during peripheral nerve regeneration." Journal of Biological Chemistry 294, no. 17 (2019): 6695. http://dx.doi.org/10.1074/jbc.aac119.008724.

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41

Marozva, Godfrey. "Africa Stock Markets Cross-Market Linkages: A Time-Varying Dynamic Conditional Correlations (DCC-GARCH) Approach." Journal of Applied Business Research (JABR) 33, no. 2 (2017): 321–28. http://dx.doi.org/10.19030/jabr.v33i2.9904.

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This article investigates stock return volatility and contagion among the five African countries (Zimbabwe, South Africa, Egypt, Kenya, and Nigeria) and the United States of America for the period between 1998 and 2015. Engle (2002)’s Dynamic Conditional Correlation multivariate generalized autoregressive conditional heteroscedasticity model was adapted to explore the time-varying conditional correlations to capture the contagion behavior of these financial markets over time. In this article the researchers observes that South African Stock returns are highly correlated to NYSE stock returns a

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42

Ham, S. H., and B. J. Sohn. "Assessment of the calibration performance of satellite visible channels using cloud targets: application to Meteosat-8/9 and MTSAT-1R." Atmospheric Chemistry and Physics Discussions 10, no. 5 (2010): 12629–64. http://dx.doi.org/10.5194/acpd-10-12629-2010.

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Abstract. To examine the calibration performance of the Meteosat-8/9 Spinning Enhanced Visible Infra-Red Imager (SEVIRI) 0.640-μm and the Multi-functional Transport Satellite (MTSAT)-1R 0.724-μm channels, three calibration methods were employed. First, a ray-matching technique was used to compare Meteosat-8/9 and MTSAT-1R visible channel reflectances with the well-calibrated Moderate Resolution Imaging Spectroradiometer (MODIS) 0.646-μm channel reflectances. Spectral differences of the response function between the two channels of interest were taken into account for the comparison. Second, co

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Abdelbaky, Ahmed S., Ivan A. Prokhorov, Elena V. Gnuskova, Olga V. Esipova, and Yulia G. Kirillova. "Convenient and Efficient Syntheses of Peptide Nucleic Acid Purine Monomers." Current Organic Chemistry 23, no. 19 (2019): 2122–30. http://dx.doi.org/10.2174/1385272823666191014161442.

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Currently, peptide nucleic acids (PNAs) play an important role as therapeutic agents, molecular tools for diagnosis and detection of genetic diseases as well as in biosensor probes. This research aims to optimize the synthesis of aeg- and &#947;-(S)-Me PNA monomers based on L-Ala, intended for oligomerization according to the Boc protocol. The monomers were obtained through the condensation of the corresponding pseudopeptides with carboxymethyl purine nucleic bases. During the work, the optimization of benzyloxycarbonyl- N6-adenine-9-yl-acetic acid and benzyloxycarbonyl-N2-guanine-9-ylacet

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Zhao, Chen, Aili Dai, Ling Chen, et al. "Epigenetic Inactivation of DBC1 in Acute Myeloid Leukaemia." Blood 114, no. 22 (2009): 4429. http://dx.doi.org/10.1182/blood.v114.22.4429.4429.

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Abstract Abstract 4429 DNA hypermethylation has important implications in the tumorigenesis and prognosis in acute myeloid leukemia (AML). To identify relevant methylated genes in AML, we have compared several expression and methylation profilings. With expression analysis, we identified that TRPC6, DBC1, DCC and SOX9 have decreased expression levels in the most analyzed AML cell lines. Among these candidates, DBC1 (deleted bladder cancer 1), a putative tumor suppressor, drew our attention because it is frequently methylated not only in hematological malignancies, including diffuse large B-cel

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Pohl, Ute, Martin W. Höhne, Wolfram H. Gerlich, and Stephan Schaefer. "Morphological and functional effects of antisense RNA to the deleted in colorectal carcinoma (DCC) gene in a pancreatic carcinoma cell line." Cancer Letters 145, no. 1-2 (1999): 9–15. http://dx.doi.org/10.1016/s0304-3835(99)00204-9.

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Nowak, D., M. Mossner, M. Klaumuenzer, et al. "254 Array based methylation analysis identifies DBC1, CDH1, DCC and WT1 as differentially methylated and prognostically relevant candidate genes in MDS." Leukemia Research 35 (May 2011): S100. http://dx.doi.org/10.1016/s0145-2126(11)70256-9.

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47

Garcia, David, Peter G. Milner, Daniel M. Canafax, and David J. Ellis. "Results of the EmbraceAC Trial: A Head-to-Head Comparison of Warfarin with Tecarfarin, A New Anticoagulant." Blood 114, no. 22 (2009): 3135. http://dx.doi.org/10.1182/blood.v114.22.3135.3135.

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Abstract Abstract 3135 Poster Board III-72 EmbraceAC was conducted to evaluate whether tecarfarin (T) is superior to optimized warfarin (W) as measured by interpolated time in therapeutic range (TTR). T is a novel vitamin K antagonist free of CYP-based metabolism. EmbraceAC was a 6-9 month randomized, double-blind, multicenter study of optimized W vs. T using a dose control center (DCC) and prospective genotyping in oral anticoagulation patients. Data from weekly INR monitoring was analyzed on an ITT basis. A total of 612 patients from 47 sites (94.3% warfarin experienced; 74.5% treated for AF

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48

Sun, Bin-Bin, Bing-Hua Yao, Yang-Qing He, and Bo Yang. "Preparation and Photochromic Performance of Homogeneous Phase Nitrocellulose Membrane Grafting Spirooxazine Moieties." Coatings 10, no. 6 (2020): 569. http://dx.doi.org/10.3390/coatings10060569.

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The synthesis of 1,3,3-trimethyl-9′-acryloxyspiro[indoline-2,3′(3H)naphtho[2,1-b][l,4]-oxazine] (AISO) was carried out by catalytic esterification of 1,3,3-trimethyl-9′-hydroxyspiro-[indoline-2,3′(3H)naphtho[2,1-b][l,4]oxazine] (SO–OH) and acrylic acid in the presence of 1,3-dicyclohexylcarbodiimide (DCC) and N-dimethylaminopyridine (DMAP). Then, the synthesis of the target copolymer (NC-g-AISO) was was carried out by benzoyl peroxide (BPO)-induced graft copolymerization of the AISO monomer onto nitrocellulose (NC) in a homogeneous methyl isobutyl ketone medium. The structure of NC-g-AISO was

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Chan, S. S. Y., H. Zheng, M. W. Su, et al. "UNC-40, a C. elegans Homolog of DCC (Deleted in Colorectal Cancer), Is Required in Motile Cells Responding to UNC-6 Netrin Cues." Cell 87, no. 2 (1996): 187–95. http://dx.doi.org/10.1016/s0092-8674(00)81337-9.

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50

Ham, S. H., and B. J. Sohn. "Assessment of the calibration performance of satellite visible channels using cloud targets: application to Meteosat-8/9 and MTSAT-1R." Atmospheric Chemistry and Physics 10, no. 22 (2010): 11131–49. http://dx.doi.org/10.5194/acp-10-11131-2010.

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Abstract. To examine the calibration performance of the Meteosat-8/9 Spinning Enhanced Visible Infra-Red Imager (SEVIRI) 0.640-μm and the Multi-functional Transport Satellite (MTSAT)-1R 0.724-μm channels, three calibration methods are employed. Total eight months during the 2004–2007 period are used for SEVIRI, and total seven months during the 2007–2008 period are used for MTSAT-1R. First, a ray-matching technique is used to compare Meteosat-8/9 and MTSAT-1R visible channel reflectances with the well-calibrated Moderate Resolution Imaging Spectroradiometer (MODIS) 0.646-μm channel reflectance

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