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1

Zhang, Linping, Yanting Zhu, Xiaoming Wang, Zhenjiang Li, and Qianlan Dong. "Immuno-Nanoparticles Developed Using Dexamethasone and Captopril Co-Loaded PLGA Improve Glomerulonephritis Through Modulating Macrophage Polarization." Journal of Biomedical Nanotechnology 19, no. 10 (2023): 1685–96. http://dx.doi.org/10.1166/jbn.2023.3615.

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The purpose of this study was to prepare liposome-coated poly(lactic-co-glycolic acid) co-loaded with dexamethasone (DXMS, D) and captopril (CAP, C) loading with PLGA nanoparticles (P) and modified polyethylene glycol and integrin α8 antibody on the surface of nanoparticles to obtain double-drug-loaded core–shell immunoliposome composite nanoparticles (DCPI), and then studied the loading Kidney targeting, anti-inflammatory effects and effects on macrophage differentiation of drug nanoparticles. In vitro cell experiments showed that DCPI could reduce the secretion of M2 macrophage-specific cyto
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Halala, Yitagesu, Samuel Tafesse, and Henok Teferi. "The Use of Dynamic Cone Penetrometer to Predict California Bearing Ratio Value of Subgrade Soils." American Journal of Civil Engineering 12, no. 5 (2024): 169–77. http://dx.doi.org/10.11648/j.ajce.20241205.12.

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California Bearing Ratio (CBR) is an indirect method mostly used to investigate the strength of subgrade material for highway design. The CBR of subgrade materials can be determined from costly and time-taking laboratory or in situ CBR tests. These limitations suggest the need for an easy and low-cost in situ direct method to estimate the CBR of subgrade materials. Dynamic cone penetration (DCP) is easy, quick, and economical in situ test in geotechnical uses. However, the use of DCP test to evaluate the CBR of subgrade material is condition specific i.e., local conditions should be considered
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KNIPFEL, J. E., J. A. KERNAN, E. C. COXWORTH, and R. D. H. COHEN. "THE EFFECT OF STAGE OF MATURITY ON THE NUTRITIVE VALUE OF KOCHIA." Canadian Journal of Animal Science 69, no. 4 (1989): 1111–14. http://dx.doi.org/10.4141/cjas89-130.

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A trial was conducted to determine the nutritive value for sheep of kochia (Kochia scoparia L. Schrad) grown on saline soil and harvested at the early seed stage and the full bloom stage of maturity. There was a significant decrease in digestible organic matter intake (DOMI) and digestible crude protein intake (DCPI) with increasing kochia maturity (31.6 vs. 23.2 g DOMI kg−0.75 (SE = 0.6; P < 0.05) and 4.22 vs. 1.41 g DCPI kg−0.75 (SE < 0.001; P < 0.05)). Early cut kochia appears to be at least equivalent in digestible energy to alfalfa, but lower in digestible protein. Key words: Koc
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Daljeet, Singh1 *. J.N.Jha2 K.S.Gill3. "EFFECT OF FIELD MOISTURE CONTENT ON PENETRATION INDEX VALUE OF DYNAMIC CONE PENETROMETER IN ALLUVIAL SOIL SUBGRADES." INTERNATIONAL JOURNAL OF ENGINEERING SCIENCES & RESEARCH TECHNOLOGY 6, no. 7 (2017): 327–33. https://doi.org/10.5281/zenodo.827508.

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Dynamic Cone Penetrometer is an ideal instrument for testing subgrade and embankment compaction and it in-situ California Bearing Ratio (CBR). The Dynamic Cone Penetration Index (DCPI) value has valid correlation with CBR. The relation has higher value of coefficient of determination, denoted as R<sup>2</sup>, for non-cohesive soils dry soils. The fine grained alluvial soils having some Plasticity Index (PI) value shows the lower R<sup>2</sup> value. The Various alluvial soil samples having PI value from 0 to 10 were tested for finding the moisture correction factor so that DCPI values can be
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Lwanda, Vincent, Duwa Chengula, and Mwajuma Lingwanda. "Determination of Dynamic Cone Penetration Index (DCPI) of Borrow Pit Materials for Construction of Low Volume Roads in Dodoma Tanzania." Mbeya University of Science and Technology Journal of Research and Development 5, no. 4 (2024): 1–14. https://doi.org/10.62277/mjrd2024v5i40065.

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The study for determination of dynamic cone penetration index (DCPI) of borrow pit materials for construction of low-volume roads was conducted in the Dodoma region in Tanzania. Samples for tests were collected from five borrow pits, which are Nkulabi, Zuzu, Mahomanyika, Dinda, and Ntyuka. Results of plasticity indices were 14%, 11%, 10%, 16%, and 13% for Nkulabi, Zuzu, Mahomanyika, Dinda, and Ntyuka borrow pits, respectively. Results of grading coefficients and shrinkage products were 33.7 and 148.1 units for Nkulabi, 19.9 and 295.9 units for Zuzu, 32.3 and 56.0 units for Mahomanyika, 25.4 an
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Nursar, Achmad Satria, Iswan Iswan, and Setyanto Setyanto. "Komparasi Nilai Daya Dukung Tanah Lempung Ditinjau dari Hasil Uji Skala Penetrasi Konus Dinamis, Uji CBR Laboratorium dan Uji Kuat Tekan Bebas." Jurnal Rekayasa Sipil dan Desain 3, no. 2 (2016): 193–204. https://doi.org/10.23960/jrsdd.v3i2.451.

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Soil bearing capacity can be determined with several kind of test, that could produce different testresult for same sample in accordance to characteristics of test equipment and main targets of eachtest equipment in determining soil parameters. This research aimed to compare characteristics ofsoil bearing capacity that obtained from DCP (Dynamic Cone Penetrometer) test, LaboratoryCBR test, and UCS (Unconfined Compressive Strength) test.The soil sample which tested on this research was from Margakaya village and Palputih village,District of Jati Agung, South Lampung and Blimbing Sari village, D
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7

Milic, Jovana V., and Simon C. Boehme. "A New Chapter for Swiss Materials Chemistry." CHIMIA 78, no. 3 (2024): 165–66. http://dx.doi.org/10.2533/chimia.2024.165.

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The division dedicated to materials chemistry at the Swiss Chemical Society (SCS) has been recently restructured by merging the Division for Polymers, Colloids, and Interfaces (DCPI) with the Materials Chemistry Network (MatChem). This column provides more insights into the process while outlining the vision and activities of the newly established SCS Division of Materials Chemistry (DMC).
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Taiwo, Saheed Mayowa, and Hyung-Koo Yoon. "Estimation of elastic wave velocity and DCPI distributions using outlier analysis." Engineering Geology 247 (December 2018): 129–44. http://dx.doi.org/10.1016/j.enggeo.2018.10.027.

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9

OLALERU, F., and T. A. ADEGBOLA. "EFFECTS OF SOURCE AND LEVEL OF NITROGEN ON THE UTILIZATION OF SORGHUM STOVER BY YANKASA RAMS." Nigerian Journal of Animal Production 28, no. 2 (2021): 187–92. http://dx.doi.org/10.51791/njap.v28i2.1909.

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The effects of cotton seed cake (CSC) or urea in supplying either 12% or 16% crude protein on sorghum stover utilization by Yankasa rams was studied for twelve weeks, using a 2 x 2 factorially designed experiment. Nutrient intake, digestibility, weight gain and feed conversion ratio (FCR) were monitored. In vitro volatile fatty acid (VFA) and ammonia-nitrogen (NH,-N) concentrations were also determined. The result of the study indicated that the source and/or level of nitrogen (or crude protein) significantly (P&lt;0.05) affected crude protein intake (CPI), digestible crude protein intake (DCP
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Mikyška, Alexandr, and Marie Jurková. "Study on the effect of malt and decoction mashing on polyphenols and antiradical power of wort." KVASNY PRUMYSL 70, no. 1 (2024): 846–54. http://dx.doi.org/10.18832/kp2024.70.846.

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Mashing is one of the key operations in beer brewing. Together with polyphenolic compounds it can affect the quality and stability of beer. In our pilot brewing trials of pale lager (200 L), malts of three barley varieties were compared using either infusion or double decoction mashing. Total polyphenols, anthocyanogens and flavanoids were determined in sweet and hopped wort. Free phenolics were measured by HPLC coupled with coulometric detection. Antiradical power was determined by RC-DCPI, ARA-DPPH and ESR-T150 methods. In this way the influence of mashing method and barley variety on polyph
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Doyle, PT. "Supplementation of rice straw with dry leucaena." Australian Journal of Agricultural Research 40, no. 2 (1989): 381. http://dx.doi.org/10.1071/ar9890381.

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The effects of supplementation with three levels (5, 10 and 15% of DM offered) of dry leucaena on the voluntary intake and digestion of rice straw by sheep were studied. These effects were compared with those of a supplement of urea and sulfate. In all cases, the rice straw was supplemented with minerals.Total dry matter intake (DMI) increased linearly with the level of leucaena, but there was no affect on intake of straw. Nor did supplementation with urea and sulfate affect straw intake. Neither of these supplements affected the apparent digestibility of organic matter (OM).There were signifi
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Lall, Sabbi, Fabio Piano, and Richard E. Davis. "Caenorhabditis elegans Decapping Proteins: Localization and Functional Analysis of Dcp1, Dcp2, and DcpS during Embryogenesis." Molecular Biology of the Cell 16, no. 12 (2005): 5880–90. http://dx.doi.org/10.1091/mbc.e05-07-0622.

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Though posttranscriptional regulation is important for early embryogenesis, little is understood regarding control of mRNA decay during development. Previous work defined two major pathways by which normal transcripts are degraded in eukaryotes. However it is not known which pathways are key in mRNA decay during early patterning or whether developmental transcripts are turned over via specific pathways. Here we show that Caenorhabditis elegans Dcp2 is localized to distinct foci during embryogenesis, reminiscent of P-bodies, the sites of mRNA degradation in yeast and mammals. However the decapp
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Schiaffini, Marlene, Clara Chicois, Aude Pouclet, et al. "A NYN domain protein directly interacts with DECAPPING1 and is required for phyllotactic pattern." Plant Physiology 188, no. 2 (2021): 1174–88. http://dx.doi.org/10.1093/plphys/kiab529.

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Abstract In eukaryotes, general mRNA decay requires the decapping complex. The activity of this complex depends on its catalytic subunit, DECAPPING2 (DCP2), and its interaction with decapping enhancers, including its main partner DECAPPING1 (DCP1). Here, we report that in Arabidopsis thaliana, DCP1 also interacts with a NYN domain endoribonuclease, hence named DCP1-ASSOCIATED NYN ENDORIBONUCLEASE 1 (DNE1). Interestingly, we found DNE1 predominantly associated with DCP1, but not with DCP2, and reciprocally, suggesting the existence of two distinct protein complexes. We also showed that the cata
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14

Xin, Ren Long, Fu Zeng Ren, Guang Jie Huang, and Yang Leng. "A Novel Method to Synthesize Nanocrystalline Calcium Phosphates." Advanced Materials Research 47-50 (June 2008): 956–59. http://dx.doi.org/10.4028/www.scientific.net/amr.47-50.956.

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This study reports a novel method for the preparation of several biologically important calcium phosphate (Ca-P) phases such as hydroxyapatite (HA), dicalcium phosphate dihydrate (DCPD) and dicalcium phosphate anhydrous (DCPA). X-ray diffraction (XRD) results showed that phase pure DCPD, DCPA and HA nano-crystals could be produced in the Ca2+/PO4 3- solutions with the presence of EDTA at 120 oC, 180 oC and 210 oC, respectively. Transmission electron microscope (TEM) micrographs revealed that all the Ca-P precipitates were needle-like or rod-like. Most of the precipitates ranged from 100 ~ 200
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Cohen, R. D. H., K. A. Cruise, J. A. Kernan, E. C. Coxworth, and J. E. Knipfel. "The effect of ammoniation on the nutritive value of tall wheatgrass." Canadian Journal of Plant Science 71, no. 3 (1991): 867–70. http://dx.doi.org/10.4141/cjps91-125.

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Tall wheatgrass (TWG, Agropyron elongatum (Host) Beauvois) was harvested at anthesis, ammoniated, fed to sheep and its nutritive value was compared with that of nonammoniated TWG. Ammoniation increased organic matter digestibility (OMD) from 59.2 to 65.9% (SEM = 1.45; P &lt; 0.001), acid detergent fibre digestibility (ADFD) from 53.2 to 63.4% (SEM = 2.14; P &lt; 0.001), neutral detergent fibre digestibility (NDFD) from 55.2 to 69.3% (SEM = 2.90; P &lt; 0.001), digestible organic matter (DOMI) from 25.8 to 44.3 g kg−0.75 d−1 (SEM = 3.90; P &lt; 0.001) and digestible crude protein intake (DCPI)
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Benu, Imanuel, I. Gusti Ngurah Jelantik, Cardial LO Penu, and Meity Marviana Laut. "Effect of Replacing Grass Silage with Hydroponic Maize Fodder on Nutrient Intake and Digestibility, Rumen Parameters and Blood Metabolites of Weaned Ongole x Brahman Calves." Jurnal Ilmu Ternak dan Veteriner 29, no. 1 (2024): 36–44. http://dx.doi.org/10.14334/jitv.v29i1.3331.

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Hydroponic maize fodder (HMF) may replace grass silage as an alternative green forage for ruminants during dry seasons. An in vivo experiment was conducted to investigate the effect of replacing grass silage with HMF on nutrient intake, nutrient digestibility, rumen parameters and blood metabolites of weaned calves. Four weaned Ongole x Brahman calves (BW= 127±17.45 kg) were fed 70% grass silage + 30% concentrates (G; control), 35% grass silage + 35% HMF + 30% concentrates (GCF1), 17,5% grass silage + 52,5% HMF + 30% concentrates (GCF2), and 70% HMF + 30% concentrates (GCF3) in a 4 x 4 Latin S
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Abaturov, A. E., and V. L. Babуch. "Mechanisms of action of cytoplasmic miRNAs. Part 4. Recruitment of the DCP1-DCP2 decapping complex. Mechanisms of final mRNA degradation." CHILD`S HEALTH 17, no. 5 (2022): 256–61. http://dx.doi.org/10.22141/2224-0551.17.5.2022.1526.

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This scientific review deals with the mechanisms of action of cytoplasmic microRNAs, namely post-transcriptional silencing: recruitment of the DCP1-DCP2 decapping complex and disruption of the interaction of mRNA with ribosomes. To write the article, information was searched using Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE, Global Health, The Cochrane Library, CyberLeninka databases. The authors indicate that the key process that determines both mRNA stability and expression efficiency is the removal of the 5’-terminal cap. Decapping of mRNA is controlled by several direct
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Cohen, Leah S., Claudette Mikhli, Xinfu Jiao, Megerditch Kiledjian, Glenna Kunkel, and Richard E. Davis. "Dcp2 Decaps m2,2,7GpppN-Capped RNAs, and Its Activity Is Sequence and Context Dependent." Molecular and Cellular Biology 25, no. 20 (2005): 8779–91. http://dx.doi.org/10.1128/mcb.25.20.8779-8791.2005.

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ABSTRACT Hydrolysis of the mRNA cap plays a pivotal role in initiating and completing mRNA turnover. In nematodes, mRNA metabolism and cap-interacting proteins must deal with two populations of mRNAs, spliced leader trans-spliced mRNAs with a trimethylguanosine cap and non-trans-spliced mRNAs with a monomethylguanosine cap. We describe here the characterization of nematode Dcp1 and Dcp2 proteins. Dcp1 was inactive in vitro on both free cap and capped RNA and did not significantly enhance Dcp2 activity. Nematode Dcp2 is an RNA-decapping protein that does not bind cap and is not inhibited by cap
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M Sisodia, Er Karmavirsinh. "Sub-Grade Soil Assessment Using Correlation Between Dynamic Cone Penetration Indexes (DCPI) Unconfined Compressive Strength (UCS)." International Journal for Research in Applied Science and Engineering Technology V, no. VIII (2017): 45–49. http://dx.doi.org/10.22214/ijraset.2017.8008.

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Ngele, M. B., T. A. Adegbola, S. E. F. Bogoro, M. Abubakar, and D. J. U. Kalla. "Nutrient intake, digestibility and growth performance of Yankasa sheep fed urea-treated or untreated rice straw with supplements." Nigerian Journal of Animal Production 37, no. 1 (2021): 61–70. http://dx.doi.org/10.51791/njap.v37i1.649.

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A study was conducted at the Abubakar Tafawa Balewa University (ATBU) Research and Teaching Farm between December and May 2006 to determine nutrient intake, digestibility and growth performance in Yankasa rams fed urea-treated (UTRS) and untreated rice straw (URS) with supplementation. Thirty-two (32) Yankasa rams with an average weigh of 17.5kg, and aged 1.5 to 2 years old were alloted to eight (8) dietary treatments with four (4) rams per treatment in a 2 x 4 factorial design. The two basal feeds were urea0treated rice straw (UTRS) and untreated rice straw (URS). The supplements were maize b
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Doyle, PT, and CE McLaren. "Utilization of clover diets by sheep. 2. Intake, digestion and utilization of nitrogen and sulfur." Australian Journal of Agricultural Research 39, no. 5 (1988): 881. http://dx.doi.org/10.1071/ar9880881.

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Nine mature Merino wethers were fed three clover diets at 95% of previously measured intake under steady state conditions. The diets were mature subterranean clover (MSC), green subterranean clover (GSC) and persian clover (PC). The utilization of dietary N and S was studied for each feed.The ratios of digestible organic matter (DOM) to crude protein (CP) in the diets ranged from 3.9 to 5.5 : 1. The flow of microbial crude protein (MCP) from the abomasum was only 34 g day-1 in sheep given MSC compared to 77 g day-1 for GSC and 85 g day-1 for PC. However, the calculated efficiencies of MCP synt
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Asiedu, F. H. K., and S. K. Karikari. "Energy and protein content and intake by stall-fed lambs of pure and mixed swards of Centrosema pubescens Benth., Pueraria phaseoloides Benth. and Brachiaria mutica Stapf. under a mango plantation." Journal of Agricultural Science 104, no. 1 (1985): 47–59. http://dx.doi.org/10.1017/s0021859600042970.

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SummaryPure and mixed swards of Centrosema pubescens (centro), Pueraria phaseoloides (puero) and Brachiaria mutica (para grass) established under a 12-year-old mango plantation were sampled at 6-week intervals for 2 years to determine crude-protein (CP) content, dry-matter (D.M.) and CP yields and apparent digestible energy and apparent digestible crude-protein (DCP) contents. Daily dry-matter intake (DMI) and apparent digestible energy and digestible crude-protein intakes (DEI and DCPI), as well as live-weight gain (LWG) by 11·5 kg penned West African cross-bred weaner lambs, were also determ
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Li, Li Yi, Qi Ming Chen, Jia Xi Liu, He Zhu, and Guang Jun Tan. "The Research on Switch-Linear Hybrid of Precise Current Source." Applied Mechanics and Materials 416-417 (September 2013): 559–64. http://dx.doi.org/10.4028/www.scientific.net/amm.416-417.559.

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In this paper, a novel current control strategy of precise current source is presented, which combines switch power conversion mode with linear amplification mode. The linear power amplifier is used as the power converter in the current loop. The current controller is a double cascaded PI (DCPI) controller which is put up by the way of analog circuit, it can suppress the high frequency disturbance signal effectively. The switch-filter circuit can generate a special power supply for linear power amplifier, the voltage of this special power supply changes as the load voltage does. The topology o
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Charenton, Clément, Claudine Gaudon-Plesse, Régis Back, et al. "Pby1 is a direct partner of the Dcp2 decapping enzyme." Nucleic Acids Research 48, no. 11 (2020): 6353–66. http://dx.doi.org/10.1093/nar/gkaa337.

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Abstract Most eukaryotic mRNAs harbor a characteristic 5′ m7GpppN cap that promotes pre-mRNA splicing, mRNA nucleocytoplasmic transport and translation while also protecting mRNAs from exonucleolytic attacks. mRNA caps are eliminated by Dcp2 during mRNA decay, allowing 5′-3′ exonucleases to degrade mRNA bodies. However, the Dcp2 decapping enzyme is poorly active on its own and requires binding to stable or transient protein partners to sever the cap of target mRNAs. Here, we analyse the role of one of these partners, the yeast Pby1 factor, which is known to co-localize into P-bodies together w
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Charenton, Clément, and Marc Graille. "mRNA decapping: finding the right structures." Philosophical Transactions of the Royal Society B: Biological Sciences 373, no. 1762 (2018): 20180164. http://dx.doi.org/10.1098/rstb.2018.0164.

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In eukaryotes, the elimination of the m 7 GpppN mRNA cap, a process known as decapping, is a critical, largely irreversible and highly regulated step of mRNA decay that withdraws the targeted mRNAs from the pool of translatable templates. The decapping reaction is catalysed by a multi-protein complex formed by the Dcp2 catalytic subunit and its Dcp1 cofactor, a holoenzyme that is poorly active on its own and needs several accessory proteins (Lsm1–7 complex, Pat1, Edc1–2, Edc3 and/or EDC4) to be fully efficient. Here, we discuss the several crystal structures of Dcp2 domains bound to various pa
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Wurm, Jan Philip, Iris Holdermann, Jan H. Overbeck, Philipp H. O. Mayer, and Remco Sprangers. "Changes in conformational equilibria regulate the activity of the Dcp2 decapping enzyme." Proceedings of the National Academy of Sciences 114, no. 23 (2017): 6034–39. http://dx.doi.org/10.1073/pnas.1704496114.

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Crystal structures of enzymes are indispensable to understanding their mechanisms on a molecular level. It, however, remains challenging to determine which structures are adopted in solution, especially for dynamic complexes. Here, we study the bilobed decapping enzyme Dcp2 that removes the 5′ cap structure from eukaryotic mRNA and thereby efficiently terminates gene expression. The numerous Dcp2 structures can be grouped into six states where the domain orientation between the catalytic and regulatory domains significantly differs. Despite this wealth of structural information it is not possi
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Yu, Gu-Sheng, Teresa B. Freedman, and Laurence A. Nafie. "Dual circular polarization Raman optical activity of related terpene molecules: Comparison of backscattering DCPI and right-angle ICP spectra." Journal of Raman Spectroscopy 26, no. 8-9 (1995): 733–43. http://dx.doi.org/10.1002/jrs.1250260821.

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Mugridge, Jeffrey S., Marcin Ziemniak, Jacek Jemielity, and John D. Gross. "Structural basis of mRNA-cap recognition by Dcp1–Dcp2." Nature Structural & Molecular Biology 23, no. 11 (2016): 987–94. http://dx.doi.org/10.1038/nsmb.3301.

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She, Meipei, Carolyn J. Decker, Dmitri I. Svergun, et al. "Structural Basis of Dcp2 Recognition and Activation by Dcp1." Molecular Cell 29, no. 3 (2008): 337–49. http://dx.doi.org/10.1016/j.molcel.2008.01.002.

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Cambra-López, María, Verónica Moset, María del Carmen López, et al. "Evaluation of Phosphorus Digestibility from Monocalcium and Dicalcium Phosphate Sources and Comparison between Total Tract and Prececal Digestibility Standard Methods in Broilers." Animals 11, no. 12 (2021): 3427. http://dx.doi.org/10.3390/ani11123427.

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The objective of this study was to compare the total tract (total excreta and marker) and prececal methodologies to determine phosphorus (P) digestibility and to evaluate its variation as a function of the physicochemical characteristics of the inorganic phosphate used (monocalcium, MCP and dicalcium, DCP) from different commercial sources. A total of 176 1-day-old male broilers were used in two digestibility experiments. In Experiment 1, one MCP and one DCP were incorporated in the basal diet at two levels. In Experiment 2, MCP and DCP from three commercial sources were incorporated to the ba
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Harigaya, Yuriko, Brittnee N. Jones, Denise Muhlrad, John D. Gross, and Roy Parker. "Identification and Analysis of the Interaction between Edc3 and Dcp2 in Saccharomyces cerevisiae." Molecular and Cellular Biology 30, no. 6 (2010): 1446–56. http://dx.doi.org/10.1128/mcb.01305-09.

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ABSTRACT Cap hydrolysis is a critical control point in the life of eukaryotic mRNAs and is catalyzed by the evolutionarily conserved Dcp1-Dcp2 complex. In Saccharomyces cerevisiae, decapping is modulated by several factors, including the Lsm family protein Edc3, which directly binds to Dcp2. We show that Edc3 binding to Dcp2 is mediated by a short peptide sequence located C terminal to the catalytic domain of Dcp2. This sequence is required for Edc3 to stimulate decapping activity of Dcp2 in vitro, for Dcp2 to efficiently accumulate in P-bodies, and for efficient degradation of the RPS28B mRNA
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Sugiyama, Tomoaki, Shusuke Akiyama, and Toshiyuki Ikoma. "Calcium phosphate with high specific surface area synthesized by a reverse micro-emulsion method." MRS Advances 1, no. 11 (2016): 723–28. http://dx.doi.org/10.1557/adv.2016.68.

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ABSTRACTA reverse micro-emulsion method has been investigated to control crystal morphology in a nanometer region and to increase specific surface area for calcium phosphate. The nanocrystals with the control of its morphology is a candidate of drug delivery carriers. This study investigated the effects of mixing volume ratios of two surfactants, tween80 (T) and aliquate 336 (A) in kerosene as an oil phase, and pH values in the nano-region on crystalline phases and specific surface area of calcium phosphate synthesized by the reverse micro-emulsion method. A di-ammonium hydrogen phosphate solu
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Wang, Chun-Yu, Wen-Ling Chen, and Shao-Win Wang. "Pdc1 Functions in the Assembly of P Bodies in Schizosaccharomyces pombe." Molecular and Cellular Biology 33, no. 6 (2013): 1244–53. http://dx.doi.org/10.1128/mcb.01583-12.

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P bodies are cytoplasmic RNA granules containing the Dcp1-Dcp2 decapping enzymes where mRNA decay can occur. Here, we describe the characterization of P bodies in the fission yeastSchizosaccharomyces pombe. Most information on the property and function of P bodies stems from studies in the distantly related budding yeastSaccharomyces cerevisiae, and Edc3 was identified as a scaffold protein required for P-body assembly. However, we found that, unlike inS. cerevisiae, fission yeast Edc3 was dispensable for P-body formation. Pdc1, a novel partner of the fission yeast decapping enzyme, with a lim
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M Sisodia, Er Karmavirsinh. "Sub-Grade Soil Assessment Using Correlation Between Dynamic Cone Penetration Index (DCPI) California Bearing Ratio(CBR): A Case Study of PMGSY Roads." International Journal for Research in Applied Science and Engineering Technology V, no. VIII (2017): 39–44. http://dx.doi.org/10.22214/ijraset.2017.8007.

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Borja, M. S., K. Piotukh, C. Freund, and J. D. Gross. "Dcp1 links coactivators of mRNA decapping to Dcp2 by proline recognition." RNA 17, no. 2 (2010): 278–90. http://dx.doi.org/10.1261/rna.2382011.

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Valkov, Eugene, Sowndarya Muthukumar, Chung-Te Chang, Stefanie Jonas, Oliver Weichenrieder, and Elisa Izaurralde. "Structure of the Dcp2–Dcp1 mRNA-decapping complex in the activated conformation." Nature Structural & Molecular Biology 23, no. 6 (2016): 574–79. http://dx.doi.org/10.1038/nsmb.3232.

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AMBATI, CHANDRA MOULI, Devasena, Suryanarayana MVAN, GANGARAJU G, and SNEHA SHARADA MADA. "Effect of Different Feeding Methods on Milk Production and Composition of Lactating Punganur Cows." International Journal of Bio-resource and Stress Management 14, Sep, 9 (2023): 1234–42. http://dx.doi.org/10.23910/1.2023.3591c.

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The present experiment was conducted during January–August, 2021 at Livestock Research Station, Palamaner, Chittoor, Andhra Pradesh, India to study the effect of different feeding methods on production performance in lactating Punganur cows. A lactation study of 90 days duration was conducted on 16 lactating Punganur cows which were distributed (CRD) into four treatment groups comprising of 4 animals each. Animals of Control group were maintained as per the feeding practice followed by the farmers rearing Punganur cows in Chittoor district (Hedge lucerne, Paddy straw and Concentrate mixture),
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Xu, Jun, Jun-Yi Yang, Qi-Wen Niu, and Nam-Hai Chua. "Arabidopsis DCP2, DCP1, and VARICOSE Form a Decapping Complex Required for Postembryonic Development." Plant Cell 18, no. 12 (2006): 3386–98. http://dx.doi.org/10.1105/tpc.106.047605.

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Tritschler, Felix, Ana Eulalio, Vincent Truffault, et al. "A Divergent Sm Fold in EDC3 Proteins Mediates DCP1 Binding and P-Body Targeting." Molecular and Cellular Biology 27, no. 24 (2007): 8600–8611. http://dx.doi.org/10.1128/mcb.01506-07.

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ABSTRACT Members of the (L)Sm (Sm and Sm-like) protein family are found across all kingdoms of life and play crucial roles in RNA metabolism. The P-body component EDC3 (enhancer of decapping 3) is a divergent member of this family that functions in mRNA decapping. EDC3 is composed of a N-terminal LSm domain, a central FDF domain, and a C-terminal YjeF-N domain. We show that this modular architecture enables EDC3 to interact with multiple components of the decapping machinery, including DCP1, DCP2, and Me31B. The LSm domain mediates DCP1 binding and P-body localization. We determined the three-
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Chang, Chung-Te, Natalia Bercovich, Belinda Loh, Stefanie Jonas, and Elisa Izaurralde. "The activation of the decapping enzyme DCP2 by DCP1 occurs on the EDC4 scaffold and involves a conserved loop in DCP1." Nucleic Acids Research 42, no. 8 (2014): 5217–33. http://dx.doi.org/10.1093/nar/gku129.

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41

Labgairi, K., A. Borji, M. Kaddami, and A. Jourani. "Kinetic Study of Calcium Phosphate Precipitation in the System H3PO4-Ca(OH)2-H2O at 30°C." International Journal of Chemical Engineering 2020 (November 10, 2020): 1–9. http://dx.doi.org/10.1155/2020/2893298.

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The precipitation kinetics of calcium phosphates, namely, hydroxyapatite (HAP), dicalcium phosphate dihydrate (DCPD), dicalcium phosphate anhydrous (DCPA), and monocalcium phosphate monohydrate (MCPM), were studied at 30°C by mixing calcium hydroxide, water, and phosphoric acid. The studied mixture was selected according to the stability domain of different calcium phosphates by referring to the phase diagram of the ternary system of H3PO4-Ca(OH)2-H2O at 30°C. The precipitation reaction has been monitored by following the changes in the conductivity, pH, and calcium concentration. The solid ph
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Motomura, Kazuki, Quy T. N. Le, Takahiro Hamada, et al. "Diffuse Decapping Enzyme DCP2 Accumulates in DCP1 Foci Under Heat Stress in Arabidopsis thaliana." Plant and Cell Physiology 56, no. 1 (2014): 107–15. http://dx.doi.org/10.1093/pcp/pcu151.

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Tritschler, Felix, Ana Eulalio, Sigrun Helms, et al. "Similar Modes of Interaction Enable Trailer Hitch and EDC3 To Associate with DCP1 and Me31B in Distinct Protein Complexes." Molecular and Cellular Biology 28, no. 21 (2008): 6695–708. http://dx.doi.org/10.1128/mcb.00759-08.

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ABSTRACT Trailer Hitch (Tral or LSm15) and enhancer of decapping-3 (EDC3 or LSm16) are conserved eukaryotic members of the (L)Sm (Sm and Like-Sm) protein family. They have a similar domain organization, characterized by an N-terminal LSm domain and a central FDF motif; however, in Tral, the FDF motif is flanked by regions rich in charged residues, whereas in EDC3 the FDF motif is followed by a YjeF_N domain. We show that in Drosophila cells, Tral and EDC3 specifically interact with the decapping activator DCP1 and the DEAD-box helicase Me31B. Nevertheless, only Tral associates with the transla
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Vukovic, Ivana, Samantha M. Barnada, Jonathan W. Ruffin, et al. "Non-redundant roles for the human mRNA decapping cofactor paralogs DCP1a and DCP1b." Life Science Alliance 7, no. 11 (2024): e202402938. http://dx.doi.org/10.26508/lsa.202402938.

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Eukaryotic gene expression is regulated at the transcriptional and post-transcriptional levels, with disruption of regulation contributing significantly to human diseases. The 5′ m7G mRNA cap is a central node in post-transcriptional regulation, participating in both mRNA stabilization and translation efficiency. In mammals, DCP1a and DCP1b are paralogous cofactor proteins of the mRNA cap hydrolase DCP2. As lower eukaryotes have a single DCP1 cofactor, the functional advantages gained by this evolutionary divergence remain unclear. We report the first functional dissection of DCP1a and DCP1b,
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Lobel, Joseph H., Ryan W. Tibble, and John D. Gross. "Pat1 activates late steps in mRNA decay by multiple mechanisms." Proceedings of the National Academy of Sciences 116, no. 47 (2019): 23512–17. http://dx.doi.org/10.1073/pnas.1905455116.

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Pat1 is a hub for mRNA metabolism, acting in pre-mRNA splicing, translation repression, and mRNA decay. A critical step in all 5′-3′ mRNA decay pathways is removal of the 5′ cap structure, which precedes and permits digestion of the RNA body by conserved exonucleases. During bulk 5′-3′ decay, the Pat1/Lsm1-7 complex engages mRNA at the 3′ end and promotes hydrolysis of the cap structure by Dcp1/Dcp2 at the 5′ end through an unknown mechanism. We reconstitute Pat1 with 5′ and 3′ decay factors and show how it activates multiple steps in late mRNA decay. First, we find that Pat1 stabilizes bindin
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Kasihairani, Dara, Rahmat Hidayat, and Supari Supari. "Assessing the Reliability of Predicted Decadal Surface Temperatures in Southeast Asia." Forum Geografi 38, no. 3 (2024): 413–25. https://doi.org/10.23917/forgeo.v38i3.5402.

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Climate predictions spanning 10-year periods, known as Decadal Climate Predictions (DCPs), have become an important aspect of the latest Coupled Model Intercomparison Project (CMIP6). These DCPs have the capability to capture the El Niño-Southern Oscillation (ENSO) phenomena, which affects heatwave frequency in Southeast Asia over years to decades. This research assesses the ability of six General Circulation Model (GCM) DCPs to predict surface temperature over the Southeast Asian region, using the dcpp-A hindcast as the main product. The metrics of Anomaly Correlation Coefficient (ACC) and Me
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Olumuyiwa, Olusola Falowo*, and Anthony Oniyelu Tosin. "Engineering Geological Highway Structural Failure Assessment and Modeling of its Geotechnical Parameters: Case Study of Failed F- 209 Pavement, Southwestern Nigeria." International Journal of Ground Sediment & Water 18 (April 25, 2023): 1167–204. https://doi.org/10.5281/zenodo.7861995.

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<strong>Abstract</strong>:&nbsp;Engineering geological investigation of the soil domain along the highway alignment of F-209 connecting Akure and Ado-Ekiti Southwestern Nigeria, had been investigated to assess the structural failure of the highway. Findings showed that the subsoil delineated is characterized by resistivity ranging from 135 &ndash; 711 ohm-m (avg. 385 ohm-m) composing sandy clay and clay sand (predominant). The soils are of intermediate plasticity/compressibility; and montmorillonite clay mineralogy group. The soaked CBR/in-situ CBR values are generally less than 10% minimum sp
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Liu, H., and M. Kiledjian. "Decapping the message: a beginning or an end." Biochemical Society Transactions 34, no. 1 (2006): 35–38. http://dx.doi.org/10.1042/bst0340035.

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Removal of the mRNA 5′ cap is an important step in the regulation of mRNA stability. mRNAs are degraded by at least two distinct exonucleolytic decay pathways, one from the 5′ end, and the second from the 3′ end. Two major cellular decapping enzymes have been identified, and each primarily functions in one of the two decay pathways. The Dcp2 decapping enzyme utilizes capped mRNA as substrate and hydrolyses the cap to release m7GDP (N7-methyl GDP), while a scavenger decapping enzyme, DcpS, utilizes cap dinucleotides or capped oligonucleotides as substrate and releases m7GMP (N7-methyl GMP). In
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Sun, Yuechao, and Xiaobo Zhang. "Role of DCP1-DCP2 complex regulated by viral and host microRNAs in DNA virus infection." Fish & Shellfish Immunology 92 (September 2019): 21–30. http://dx.doi.org/10.1016/j.fsi.2019.05.058.

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Paquette, David R., Jeffrey S. Mugridge, David E. Weinberg, and John D. Gross. "Application of a Schizosaccharomyces pombe Edc1-fused Dcp1–Dcp2 decapping enzyme for transcription start site mapping." RNA 24, no. 2 (2017): 251–57. http://dx.doi.org/10.1261/rna.062737.117.

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