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Journal articles on the topic 'De-ritis ratio'

Author: Grafiati

Published: 4 June 2025

Last updated: 15 July 2025

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1

Cao, Yide, Ganyi Chen, Huangshu Li, et al. "De Ritis ratio as a significant prognostic factor of international normalized ratio ≥4 in the initial 10 days of warfarin therapy." Biomarkers in Medicine 13, no. 18 (2019): 1599–607. http://dx.doi.org/10.2217/bmm-2019-0033.

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Aim: To assess the relationship between the De Ritis ratio on admission and warfarin sensitivity in the initial 10 days of anticoagulation therapy. Methods: We retrospectively reviewed data from 906 patients who underwent heart valve replacement surgery. Results: A De Ritis ratio of 1.19 was identified as the optimal cutoff according to the ROC curve. Patients with a high De Ritis ratio achieved an international normalized ratio (INR) ≥4 more easily and earlier than those with a low De Ritis ratio in the initial 10 days of warfarin therapy. Multivariate analysis showed that a high De Ritis rat

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Lu, Zhengri, Genshan Ma, and Lijuan Chen. "De-Ritis Ratio Is Associated with Mortality after Cardiac Arrest." Disease Markers 2020 (November 4, 2020): 1–13. http://dx.doi.org/10.1155/2020/8826318.

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Introduction. The aim of our study was to explore the associations of the aspartate transaminase/alanine transaminase (De-Ritis) ratio with outcomes after cardiac arrest (CA). Methods. This retrospective study included 374 consecutive adult cardiac arrest patients. Information on the study population was obtained from the Dryad Digital Repository. Patients were divided into tertiles based on their De-Ritis ratio. The logistic regression hazard analysis was used to assess the independent relationship between the De-Ritis ratio and mortality. The Kaplan-Meier method and log-rank test were used t

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Kölükçü, Engin, Fatih Fırat, Kenan Yalçın, Şerifali Yağan Balcı, and Yunus Emre Kuyucu. "Clinical significance of pretreatment De Ritis ratio in renal cell carcinoma." Journal of Health Sciences and Medicine 7, no. 3 (2024): 247–51. http://dx.doi.org/10.32322/jhsm.1451075.

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Aims: This study aimed to investigate the relationship between pretreatment De Ritis ratio and Fuhrman nuclear grade and tumor stage in renal cell carcinoma (RCC). Methods: The data of 288 patients treated for RCC were analyzed. The De Ritis ratio was evaluated in patients classified by Fuhrman nuclear grade and tumor stage. The De Ritis ratio between groups was compared using Levene’s test. Results: A total of 145 patients (50.3%) were women female. Their mean age, aspartate aminotransferase, alanine aminotransferase values, and De Ritis ratio were as follows, respectively: 60.32±12.65 years,

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Oflazoglu, Utku, Temmuz Gurdal Insan, Yuksel Kucukzeybek, et al. "Prognostic value of De Ritis ratio (aspartate transaminase/alanine transaminase) in patients with non-metastatic colorectal carcinoma [izmir oncology group(IZOG) study]." Journal of Clinical Oncology 38, no. 15_suppl (2020): e16114-e16114. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e16114.

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e16114 Background: We aimed to assess the prognostic effect of preoperative De Ritis (aspartate aminotransaminase/Alanine aminotransaminase) ratio and pathological variables to find out whether it is an independent prognostic factor in patients with non-metastatic CRC. Methods: We retrospectively evaluated the patients who underwent curative surgery for non-metastatic CRC between 2006 and 2017. The potential prognostic value of De Ritis ratio was assessed by using a ROC curve analysis. The effect of the De Ritis ratio was analyzed by the Kaplan–Meier method and Cox regression hazard models for

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Uçar, Ayşenur, and Aynur Doğrusöz. "The Prognostic Role of In-Hospital Mortality Predictors and De Ritis Ratio in Patients with Upper Gastrointestinal System Bleeding." Pakistan Journal of Medical and Health Sciences 16, no. 6 (2022): 659–62. http://dx.doi.org/10.53350/pjmhs22166659.

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Objective: We aimed to evaluate the prognostic significance of the aspartate aminotransferase(AST) / alanine aminotransferase (ALT) named as (De Ritis) ratio in patients hospitalized in the intensive care unit with the diagnosis of upper gastrointestinal (GI) bleeding. Method: We retrospectivelyanalyzed the clinical and laboratory data of 243 patients admitted with upper GI bleeding to the intensive care unit of our tertiary hospital between January 2018 and April 2022. The potential prognostic parameters between survivors and non-survivors groups and then between low De Ritis and High De Riti

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Ndrepepa, Gjin, Salvatore Cassese, Maria Scalamogna, et al. "Association of De Ritis Ratio with Prognosis in Patients with Coronary Artery Disease and Aminotransferase Activity within and outside the Healthy Values of Reference Range." Journal of Clinical Medicine 12, no. 9 (2023): 3174. http://dx.doi.org/10.3390/jcm12093174.

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Background: The aspartate aminotransferase (AST) to alanine aminotransferase (ALT) ratio (De Ritis ratio), obtained from AST and ALT activities in the healthy range, has not been studied in association with mortality. Methods: This study included 3392 patients with stable coronary heart disease and aminotransferase activity in the reference range. Patients are categorized into two groups: a group with AST and ALT activity in the healthy range (n = 1697), and a group with AST and/or ALT activity outside the healthy range but in the reference range (n = 1695). The primary endpoint was all-cause

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FIRAT, Sevde Nur, Işılay TAŞKALDIRAN, Şerife KUŞKONMAZ, and Cavit ÇULHA. "AST/ALT (De Ritis) Ratio in Early Stage Differentiated Thyroid Cancer." Kocaeli Üniversitesi Sağlık Bilimleri Dergisi 8, no. 2 (2022): 125–28. http://dx.doi.org/10.30934/kusbed.1009993.

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Objective: Differentiated thyroid cancers are the most common endocrine cancers and their frequency is increasing with the increase in imaging possibilities. In various malignancies; Even in the absence of liver metastases, it was determined that AST value increased compared to ALT due to increased metabolism, tissue damage and rapid tumor turnover. This rate is known as the De Ritis rate, and in our study, we planned to evaluate whether there is a relationship between histopathological subtype, multifocality, disease stage and risk group and AST/ALT (De Ritis) ratio in early stage thyroid can

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Lopa, AT, B. Rusli, M. Arif, and Hardjoeno Hardjoeno. "ANALISIS KADAR ALBUMIN SERUM DENGAN RASIO DE RITIS PADA PENDERITA HEPATITIS B." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 13, no. 2 (2018): 60. http://dx.doi.org/10.24293/ijcpml.v13i2.884.

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Hepatitis is a inflammation process which may present in an acute or chronic phase. A decrease of serum albumin level may befound in liver disease. Ratio de Ritis in mild hepatitis is < 1 while in alcoholic hepatitis is >1. To analyze serum albumin level withratio de Ritis in hepatitis B patients. A cross sectional study was carried out comprising 46 subjects from October 2005 to August 2006measuring albumin level SGOT and SGPT levels using Lyasis autoanalyzer. Thirty eight males and eight females, the level of serumalbumin decreased with an average of albumin level 2.98 gr/dL (p<0.05

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9

Drácz, Bálint, Diána Czompa, Katalin Müllner, et al. "The Elevated De Ritis Ratio on Admission Is Independently Associated with Mortality in COVID-19 Patients." Viruses 14, no. 11 (2022): 2360. http://dx.doi.org/10.3390/v14112360.

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Liver damage in COVID-19 patients was documented as increased alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels or an elevated AST/ALT ratio, known as the De Ritis ratio. However, the prognostic value of the elevated De Ritis ratio in COVID-19 patients is still unknown. The aim of our study was to evaluate the prognostic value of the De Ritis ratio compared to other abnormal laboratory parameters and its relation to mortality. We selected 322 COVID-19 patients in this retrospective study conducted between November 2020 and March 2021. The laboratory parameters were mea

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10

Steininger, Matthias, Max-Paul Winter, Thomas Reiberger, et al. "De-Ritis Ratio Improves Long-Term Risk Prediction after Acute Myocardial Infarction." Journal of Clinical Medicine 7, no. 12 (2018): 474. http://dx.doi.org/10.3390/jcm7120474.

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Background: Recent evidence suggested levels of aspartate aminotransferase (AST), alanine transaminase (ALT), and AST/ALT ratio (De-Ritis ratio) were associated with a worse outcome after acute myocardial infarction (AMI). However, their value for predicting long-term prognosis remained unknown. Therefore, we investigated the prognostic potential of transaminases on patient outcome after AMI from a long-term perspective. Methods: Data of a large AMI registry including 1355 consecutive patients were analyzed. The Cox regression hazard analysis was used to assess the impact of transaminases and

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Rief, Peter, Martin Pichler, Reinhard Raggam, et al. "The AST/ALT (De-Ritis) ratio." Medicine 95, no. 24 (2016): e3843. http://dx.doi.org/10.1097/md.0000000000003843.

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12

Patil, Dattatraya H., Rishi Robert Sekar, Jeff Pearl, et al. "External validation of preoperative AST/ALT (De-Ritis) ratio as a prognostic indicator in localized and metastatic renal cell carcinoma." Journal of Clinical Oncology 34, no. 2_suppl (2016): 589. http://dx.doi.org/10.1200/jco.2016.34.2_suppl.589.

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589 Background: Recently, the De-Ritis ratio, defined as the ratio of preoperative aspartate aminotransferase (AST) to alanine aminotransferase (ALT), was shown to be an independent predictor of overall and recurrence-free survival in a European cohort with localized renal cell carcinoma (RCC). In this study, we perform an external validation of the De-Ritis ratio as a prognostic indicator in a distinct cohort of patients with localized and metastatic RCC. Methods: Patients that underwent nephrectomy for localized and metastatic RCC between 2001 and 2014 with available laboratory values within

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Keiner, Cathrine, Margaret Meagher, Dattatraya Patil, et al. "Association of De Ritis Ratio and Neutrophil Lymphocyte Ratio with renal functional decline and all-cause mortality in renal cell carcinoma." Journal of Clinical Oncology 38, no. 6_suppl (2020): 741. http://dx.doi.org/10.1200/jco.2020.38.6_suppl.741.

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741 Background: We sought to investigate utility of pre-operative neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and De Ritis Ratio as predictors of all-cause mortality (ACM) and renal functional decline renal cell carcinoma (RCC). Methods: Multi-institutional retrospective analysis of patients undergoing surgery for RCC. Multivariable analysis (MVA) was conducted to elucidate independent risk factors for ACM, de novo estimated glomerular filtration rate (eGFR)<45 ml/min/1.73m2 and eGFR<30 ml/min/1.73m2. Kaplan-Meier analysis (KMA) was used to investigate ACM, and de

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Ruhwedel, Tristan, Julian M. M. Rogasch, Kai Huang, et al. "The Prognostic Value of the De Ritis Ratio for Progression-Free Survival in Patients with NET Undergoing [177Lu]Lu-DOTATOC-PRRT: A Retrospective Analysis." Cancers 13, no. 4 (2021): 635. http://dx.doi.org/10.3390/cancers13040635.

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Background: The De Ritis ratio (aspartate aminotransferase [AST]/alanine aminotransferase [ALT]) has demonstrated prognostic value in various cancer entities. We evaluated the prognostic capability of the De Ritis ratio in patients with metastatic neuroendocrine tumors (NET) undergoing peptide receptor radionuclide therapy (PRRT). Methods: Unicentric, retrospective analysis of 125 patients with NET undergoing PRRT with [177Lu]Lu-DOTATOC (female: 37%; median age: 66 years; G1+G2 NET: 95%). The prognostic value regarding progression-free survival (PFS) was analyzed with univariable and multivari

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Park, Jun-Young, Jihion Yu, Jun Hyuk Hong, et al. "Elevated De Ritis Ratio as a Predictor for Acute Kidney Injury after Radical Retropubic Prostatectomy." Journal of Personalized Medicine 11, no. 9 (2021): 836. http://dx.doi.org/10.3390/jpm11090836.

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Acute kidney injury (AKI) is related to mortality and morbidity. The De Ritis ratio, calculated by dividing the aspartate aminotransferase by the alanine aminotransferase, is used as a prognostic indicator. We evaluated risk factors for AKI after radical retropubic prostatectomy (RRP). This retrospective study included patients who performed RRP. Multivariable logistic regression analysis and a receiver operating characteristic (ROC) curve analysis were conducted. Other postoperative outcomes were also evaluated. Among the 1415 patients, 77 (5.4%) had AKI postoperatively. The multivariable log

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Nursasmi, Ami Tri, Zelly Dia Rofinda, and Desywar. "The Relationship between Albumin Levels with SGOT, SGPT, and de Ritis Ratio in Chronic Hepatitis B Patients: A Single-Center Observational Study at Dr. M. Djamil General Hospital, Padang, Indonesia." Bioscientia Medicina : Journal of Biomedicine and Translational Research 8, no. 9 (2024): 4946–54. http://dx.doi.org/10.37275/bsm.v8i9.1074.

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Background: Chronic hepatitis B (CHB) is a persistent hepatitis B virus (HBV) infection and can cause progressive liver damage. This damage can be measured through a decrease in albumin levels and an increase in liver enzymes such as aspartate aminotransferase (AST/SGOT), alanine aminotransferase (ALT/SGPT), and de Ritis ratio (AST/ALT). This study aims to analyze the relationship between albumin levels and SGOT, SGPT, and de Ritis ratio in CHB patients. Methods: This cross-sectional retrospective analytical study involved 50 CHB patients diagnosed at Dr. M. Djamil General Hospital Padang betw

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Hamodat, Z. M. A. A., H. H. Abdulwahhab, and A. R. M. T. Hamodat. "Alpha-L-fucosidase as a putative prognostic biomarker in breast cancer." Ukrainian Biochemical Journal 96, no. 3 (2024): 57–65. http://dx.doi.org/10.15407/ubj96.03.057.

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Search for reliable biomarkers for predicting progression of breast cancer is essential in managing the disease. So, we are trying to provide new insights into the potential role of alpha-fucosidase (AFU) as a putative prognostic biomarker in breast cancer as compared to classic markers. The study included 56 women with breast cancer; 25 had early breast cancer, and the rest (31) had metastatic breast cancer. Thirty healthy women were considered a control group. Early breast cancer patients had a significantly increased (P ≤ 0.0001) AFU level compared with the control group. A non-significant

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Mangoni, Arduino A., and Angelo Zinellu. "An Updated Systematic Review and Meta-Analysis of the Association between the De Ritis Ratio and Disease Severity and Mortality in Patients with COVID-19." Life 13, no. 6 (2023): 1324. http://dx.doi.org/10.3390/life13061324.

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Patients with Coronavirus disease 2019 (COVID-19) often have elevations in markers of liver injury, particularly serum aspartate transaminase (AST) and alanine transaminase (ALT). Such alterations may affect the AST/ALT ratio (De Ritis ratio) and, potentially, clinical outcomes. We conducted an updated systematic review and meta-analysis of the association between the De Ritis ratio and COVID-19 severity and mortality in hospitalized patients. PubMed, Web of Science, and Scopus were searched between 1 December 2019 and 15 February 2023. The Joanna Briggs Institute Critical Appraisal Checklist

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GÜRLEVİK, Ercan, Hatice Şeyma AKÇA, Muhammed Tahir AKÇA, and Hilal AKÇA. "De Ritis oranının akut kolesistitteki rolü: retrospektif gözlemsel çalışma." Journal of Contemporary Medicine 13, no. 3 (2023): 388–95. http://dx.doi.org/10.16899/jcm.1210142.

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Aim Our study aimed to evaluate the relationship between the De-Ritis ratio and prognosis and mortality in patients diagnosed with cholecystitis.  Materials and Methods This retrospective observational study was conducted on patients diagnosed with acute cholecystitis who presented to the emergency medical clinic of XXX Hospital between June 1, 2020, and January 1, 2022. The Statistical Package for Social Sciences (SPSS) software (v.20; Chicago, IL, USA) was used for all statistical analyses. All results with p < 0.05 were considered statistically significant. Result

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Rahayu, Muji, Herlisa Anggraini, and Riani Widiyastuti. "PERBEDAAN RASIO DE RITIS (SGOT/SGPT) DENGAN TROPONIN I PADA PASIEN INFARK MIOKARD ELEVASI SEGMEN ST (STEMI) DENGAN ELEVASI NON SEGMEN ST (NSTEMI)." Jurnal Fatmawati Laboratory & Medical Science 2, no. 2 (2022): 80–85. http://dx.doi.org/10.33088/flms.v2i2.325.

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ABSTRAK Pendahuluan: Infark miokard (MI) merupakan kondisi ketika terjadi sumbatan pembuluh darah jantung sehingga otot jantung mengalami kerusakan karena kekurangan suplai darah dan oksigen. Miokard infark dari segi laboratorium dapat di nilai menggunakan marker CKMB, troponin, SGOT, SGPT. Pada akut miokard infark, SGOT dan SGPT sering meningkat, seiring dengan biomarker jantung seperti troponin dan CKMB. Rasio SGOT terhadap SGPT digunakan untuk menilai cedera sel hati. Hati sensitif terhadap perubahan hemodinamik karena menerima sekitar seperempat dari total curah jantung. Infark miokard ber

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Shaik, Abdul Samad, and V. S. Bharathi Lakshmi. "New Indices to Detect Acute Kidney Injury in Coronary Artery Disease Patients." Indian Journal of Cardiovascular Disease in Women 9 (March 22, 2024): 10–14. http://dx.doi.org/10.25259/ijcdw_15_2023.

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Objectives: Pre-procedure liver impairment has been revealed as a poor prognostic factor post-percutaneous coronary intervention (PCI). Recent investigations discovered that the aspartate aminotransferase-to-alanine aminotransferase ratio (De-Ritis ratio) indicates the severity of liver impairment and was related to adverse outcomes. We aimed to evaluate the predictive value of the De-Ritis ratio for contrast-associated acute kidney injury (CA-AKI). Materials and Methods: We prospectively enrolled 150 patients undergoing elective PCI between June 2022 and August 2022. Contrast-induced AKI: It

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Farahdina, Farahdina, Rendi Aji Prihaningtyas, Bagus Setyoboedi, Agnescia Clarissa Sera, and Sjamsul Arief. "Seeking Liver Fibrosis in Biliary Atresia using De Ritis Ratio." Biomolecular and Health Science Journal 7, no. 2 (2024): 96–100. https://doi.org/10.4103/bhsj.bhsj_10_24.

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Introduction: Biliary atresia (BA) is a rare and devastating pediatric liver disorder characterized by progressive obstruction or absence of the extrahepatic bile ducts within infants. One crucial aspect of understanding the disease process is the assessment of liver fibrosis. The De Ritis ratio can serve as an early screening tool for clinicians that assists in identifying patients at risk of progressive fibrosis. Combining this ratio with other noninvasive markers and imaging techniques may further enhance its accuracy in assessing the severity of fibrosis. Our study aims to investigate the

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Kanal, Yücel, Murat Ağırlar, Hatice Eftal Şeyda Kanal, Süleyman Öncü, Emin Koyun, and İdris Yakut. "THE RELATIONSHIP BETWEEN DE RITIS SCORE AND RADIAL ARTERY STENOSIS IN PATIENTS UNDERGOING CORONARY ANGIOGRAPHY VIA THE TRANSRADIAL ACCESS." Kocatepe Tıp Dergisi 26, no. 1 (2025): 10–15. https://doi.org/10.18229/kocatepetip.1502675.

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OBJECTIVE: While transradial access (TRA) coronary angiography (CAG) is recommended, radial artery stenosis (RAS) remains a significant issue in these patients. In patients with RAS, the reuse of the radial artery for CAG, as a coronary artery bypass graft, or as a conduit for hemodialysis fistula formation can pose a serious problem. The De Ritis score is defined as the ratio between the levels of aspartate transaminase (AST) and alanine transaminase (ALT) in the serum. Our study aimed to assess the relationship between RAS and the De Ritis score. MATERIAL AND METHODS: This retrospective stud

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Yin, Guangli, Changfeng Man, Shengen Liao, and Hongxia Qiu. "The Prognosis Role of AST/ALT (De Ritis) Ratio in Patients with Adult Secondary Hemophagocytic Lymphohistiocytosis." Mediators of Inflammation 2020 (December 7, 2020): 1–10. http://dx.doi.org/10.1155/2020/5719751.

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Purpose. Secondary hemophagocytic lymphohistiocytosis (sHLH) accompanied by liver involvement, characterized by hepatomegaly and increased liver enzymes, is usually associated with elevated mortality. However, the magnitude of these associations remains unknown. Our objective was to assess the associations of the aspartate transaminase/alanine transaminase (AST/ALT, De Ritis) ratio with overall survival among adult patients with sHLH. Methods. A retrospective analysis was performed on 289 patients aged 18–86 years with complete serum transaminase data at diagnosis of sHLH. Multivariate Cox reg

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Su, Wei-Ti, Cheng-Shyuan Rau, Sheng-En Chou, et al. "Association between Elevated De Ritis Ratio and Mortality Outcome in Adult Patients with Thoracoabdominal Trauma." Healthcare 10, no. 10 (2022): 2082. http://dx.doi.org/10.3390/healthcare10102082.

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The De Ritis ratio is widely used to differentiate various causes of liver disease and serves as an independent prognostic predictor for different malignancies and non-malignant illnesses. This retrospective study aimed to identify the association between the De Ritis ratio on admission and mortality outcomes in adult thoracoabdominal trauma patients. A total of 2248 hospitalized adult trauma patients with thoracoabdominal injury, defined as an abbreviated injury scale (AIS) score ≥ 1 in the thoracic and abdominal regions, between 1 January 2009, and 31 December 2019, were included. They were

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Kusumawati, Ninung Rose Diana, Damianus Galih Panunggal, Maria Mexitelia, Magdalena Sidhartani, and Agustini Utari. "Effects of probiotics and high fructose diet on De Ritis ratio, TGF-B levels, and liver histopathology of Sprague Dawley rats." Bali Medical Journal 11, no. 3 (2022): 1054–58. http://dx.doi.org/10.15562/bmj.v11i3.3397.

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Background: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. Histopathological diagnosis has been the gold standard for diagnosing and determining the severity of non-alcoholic steatohepatitis (NASH). However, this method is invasive, especially for diagnosing NASH in children. This research aimed to study the effect of probiotics on the De Ritis ratio, TGF-β levels, and histopathological changes in rats given High Fat, High Fructose (HFHFr) diet to look at the correlation between the De Ritis ratio and liver histopathology in diagnosing NAFLD. Method: Twenty

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Gaal, Sebastian, Kai Huang, Julian M. M. Rogasch, et al. "Prognostic Value of the De Ritis Ratio for Overall Survival in Patients with Metastatic Castration-Resistant Prostate Cancer Undergoing [177Lu]Lu-PSMA-617 Radioligand Therapy." Cancers 15, no. 20 (2023): 4907. http://dx.doi.org/10.3390/cancers15204907.

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The De Ritis ratio (=aspartate transaminase/alanine transaminase) has shown prognostic value in different cancer types. This is the first such analysis in prostate cancer patients undergoing radioligand therapy (RLT) with [177Lu]Lu-PSMA-617. This retrospective monocentric analysis included 91 patients with a median of 3 RLT cycles (range 1–6) and median cumulative activity of 17.3 GBq. Univariable Cox regression regarding overall survival (OS) included age, different types of previous treatment, metastatic patterns and different laboratory parameters before RLT. Based on multivariable Cox regr

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Guner, Ekrem, Kamil Gokhan Seker, Yusuf Arikan, Coshgun Huseynov, Emre Sam, and Ozdem Levent Ozdal. "The utility of De Ritis Ratio in predicting prognosis in testicular cancer." Aktuelle Urologie 51, no. 03 (2020): 285–89. http://dx.doi.org/10.1055/a-1117-2776.

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Abstract Objective We aimed to investigate the possible association between testicular cancer prognosis and De Ritis ratio (AST/ALT). Methods The medical records of all patients who underwent radical inguinal orchiectomy at a single tertiary in Istanbul, Turkey between 2006 and 2017 were retrospectively analyzed. Investigated parameters included patients’ demographics, complete blood count and blood biochemistry results, pathology results, treatment schemes, imaging results, and survival. De Ritis ratio was calculated as follows: AST/ALT. Results A total of 171 patients with a mean age of 32.6

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Akwiwu, E. C., D. U. Akpotuzor, J. E. Udosen, and J. O. Akpotuzor. "De Ritis Ratio and related Parameters among Breast Cancer Patients in a Southern Nigeria Population." Sokoto Journal of Medical Laboratory Science 7, no. 2 (2022): 95–100. http://dx.doi.org/10.4314/sokjmls.v7i2.11.

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De Ritis described the ratio between the serum levels of liver enzymes; aspartate transaminase (AST) and alanine transaminase (ALT). The central role of the liver in metabolism makes it a necessity that it functions optimally during chemotherapeutic administration, hence the consideration of associated parameters in the management of breast cancer. This study was conducted in University of Calabar Teaching Hospital, Calabar. It included 40 cases of pathologically diagnosed breast cancer female patients who were accessing post-operative chemotherapy. Another 40 apparently healthy females drawn

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Anoshia Javed, Dr. Khadija Mehboob, Amir Rashid, Asifa Majeed, Muhammad Imran Ibrahim, and Dr. Iffat Mushtaq. "Significance of serum ferritin and De Ritis ratio in non-alcoholic fatty liver disease as diagnostic markers." Journal of the Pakistan Medical Association 74, no. 4 (2024): 656–60. http://dx.doi.org/10.47391/jpma.9289.

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Objective: To ascertain the significance of serum ferritin and De Ritis ratio as diagnostic markers in patients of non-alcoholic fatty liver disease with and without type 2 diabetes mellitus. Methods: The comparative cross-sectional study was conducted from February to October 2022 at the Radiology Department of Combined Military Hospital, Rawalpindi, Pakistan, and comprised individuals aged 30-65 who were divided into 3 groups. Healthy controls formed group I, non-alcoholic fatty liver disease patients without type 2 diabetes mellitus formed group II and non-alcoholic fatty liver disease pati

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Parmar, Kumari, Ganesh Singh, Govind Gupta, Tanuja Pathak, and Sandeep Nayak. "Evaluation of De Ritis ratio in liver-associated diseases." International Journal of Medical Science and Public Health 5, no. 9 (2016): 1783. http://dx.doi.org/10.5455/ijmsph.2016.24122015322.

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Domjanović, Josipa, Tea Domjanović Škopinić, Josipa Radić, Mirko Luketin, Ivo Jeličić, and Andrija Matetic. "Performance of Derived Laboratory Biomarkers with Regard to 30-Day Mortality in Kidney Transplant Recipients with COVID-19." Life 12, no. 12 (2022): 2068. http://dx.doi.org/10.3390/life12122068.

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There are limited data on the performance of laboratory-derived biomarkers in kidney transplant recipients (KTR) with COVID-19. This observational study enrolled 65 KTR with COVID-19 who were treated at the University Hospital of Split up to March 2022. Laboratory-derived biomarkers (neutrophile-to-lymphocyte (NLR) ratio, platelet-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, De Ritis ratio, C-reactive protein (CRP)-to-albumin ratio, lactate dehydrogenase (LDH)-to-hemoglobin ratio, CRP-to-lymphocyte ratio, red cell distribution width-to-albumin ratio, platelet-to-albumin ratio, D-Dimer-to

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Uçar, Ayşenur, and Aynur Doğrusöz. "The Prognostic Role of In-Hospital Mortality Predictors and De Ritis Ratio in Patients with Upper Gastrointestinal System Bleeding." Pakistan Journal of Medical and Health Sciences 16, no. 5 (2022): 1324–26. http://dx.doi.org/10.53350/pjmhs221651324.

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Material-Method: In our tertiary hospital's intensive care unit, we studied the clinical and laboratory records of 243 patients who had been admitted with upper GIS bleeding between January 2018 and April 2022. Results: Patients with upper gastrointestinal haemorrhage who were hospitalised were 65.8% male (M/F: 56/22). Mean age was 68.611.56 years old. One cutoff value was determined for the De Ritis ratio: 1.54. The mortality rate within the hospital was 13.1%.. Conclusion: Our results showed for the first time that the De Ritis ratio was not associated with in-hospital mortality in GI bleedi

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Chang, Won Ick, Hwa Kyung Byun, Joo Ho Lee, et al. "BIOM-55. DE RITIS RATIO AS A NOVEL PROGNOSTIC BIOMARKER IN ATYPICAL MENINGIOMAS: A MULTI-INSTITUTIONAL STUDY." Neuro-Oncology 24, Supplement_7 (2022): vii17. http://dx.doi.org/10.1093/neuonc/noac209.065.

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Abstract PURPOSE To investigate the impact of prognostic serum biomarkers in newly diagnosed surgically resected intracranial atypical meningiomas. METHODS This multi-institutional study included 523 grade 2 (according to the 4th edition of WHO Classification of Tumors of the Central Nervous System) patients who underwent resection between 1998–2018. The baseline characteristics and serum laboratory data within one week after surgery were obtained for analyses investigating the association with progression/recurrence (P/R) rate or progression-free survival (PFS). Optimal cut-offs were calculat

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Sudakova, Diana P., Maiya G. Terentyeva, and Nataliya V. Mardaryeva. "DE RITIS RATIO IN STOMACH TISSUES IN MIXED-AGE PURE-BRED PIGS, GROWN UP IN THE CONDITIONS OF DIFFERENT FARMS." RUDN Journal of Agronomy and Animal Industries 14, no. 1 (2019): 81–89. http://dx.doi.org/10.22363/2312-797x-2019-14-1-81-89.

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The nature and intensity of age-related changes in the De Ritis coefficient, or the ratio of the enzyme aspartate aminotransferase to alanine aminotransferase, in the tissues of the diverticulum, cardiac, fundal and pyloric parts of the stomach of purebred different-age pigs grown in different farms were studied. The activity of enzymes was determined by spectrophotometric method in the scientific laboratory of the “Chuvash State Agricultural Academy”. It was revealed that during the four-week weaning of pigs (under growing conditions of the pig complex), the nature and intensity of the age-re

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Dewi, Ni Nyoman Gita Kharisma, Ni Luh Putu Yunia Dewi, Putu Itta Sandi Lesmana Dewi, Kadek Mercu Narapati Pamungkas, Dwijo Anargha Sindhughosa, and I. Ketut Mariadi. "Correlation of Simple Laboratory Result Parameters to CTP and MELD Scores, and the Diagnostic Role of Simple Laboratory Indexes to Cirrhosis Decompansation." Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy 25, no. 1 (2024): 27–33. http://dx.doi.org/10.24871/251202427-33.

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BackgroundCirrhosis of the liver is a final condition of all chronic liver diseases. Liver cirrhosis is the leading cause of increasing morbidity and mortality in adults worldwide. Systemic inflammation has been suggested to play an important role in causing progressive liver damage and is one of the leading causes of compensated and decompensated liver cirrhosis.Aim of StudyEvaluate the correlation of neutrophil-lymphocyte ratio (NLR), albumin-bilirubin ratio (ABR), albumin-bilirubin score (ALBI), aspartate aminotransferase to platelet ratio (APRI), albumin-creatinine ratio (ACR), lymphocyte-

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Dr., Sandeep Kumar, Manisha Roy Dr, Nupur Nelson Dr, et al. "Pre-treatment de-ritis ratio as a marker for cervical cancer: a study at regional cancer centre." International Journal of Medical Research and Review 7, no. 3 (2019): 162–69. https://doi.org/10.17511/ijmrr.2019.i03.03.

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Background: The role of AST/ALT ratio in prognostication of cancer cervix is not established in different study settings except for very few where they have highlighted on circulation of higher levels of AST and ALT in the cervical cancer patients. Moreover, there is a biological plausibility explained in one of the studies hence the study was conducted to elicit if the AST/ALT ratio could predict the prognosis of advanced cancer cervix before the initiation of treatment. Methodology: A follow up study was conducted among 122 newly diagnosed locally advanced carcinoma cervix patients in a regi

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Djakpo, Dodji Kossi, Zhi Quan Wang, and Merina Shrestha. "The significance of transaminase ratio (AST/ALT) in acute myocardial infarction." Archives of Medical Science – Atherosclerotic Diseases 5, no. 1 (2020): 279–83. http://dx.doi.org/10.5114/amsad.2020.103028.

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IntroductionFernando De Ritis described the significance of the transaminase (AST/ALT) ratio in 1957, and since then it has been commonly used to screen liver diseases. The liver is sensitive to hemodynamic changes because it receives approximately one-quarter of total cardiac output. We aimed to investigate the AST/ALT ratio changes in patients with acute myocardial infarction without any history of liver diseases in the Chinese Han population.Material and methodsWe analyzed a total of 120 patients with acute myocardial infarction admitted to the cardiology department of Zhongnan Hospital of

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Ertaş, Kasım, Recep Eryılmaz, Rahmi Aslan, Murat Demir, and Kerem Taken. "The Importance of De Ritis Ratio in Patients with Bladder Cancer." Bagcilar Medical Bulletin 5, no. 3 (2020): 69–74. http://dx.doi.org/10.4274/bmb.galenos.2020.03.09.

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Akwiwu, Euphoria C., Dennis A. Abunimye, and Josephine O. Akpotuzor. "Persistent anaemia and unresolved systemic dysfunction among persons living with HIV infection in Southern Nigeria." Sokoto Journal of Medical Laboratory Science 9, no. 2 (2024): 300–305. https://doi.org/10.4314/sokjmls.v9i2.35.

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Anaemia in human immunodeficiency virus (HIV) infection has remained a significant morbidity indicator affecting both disease progression and outcome. Its persistence despite antiretroviral therapy continues to generate interest. Reports of systemic dysfunction in association with HIV has necessitated exploring possible systemic indices for assessment and monitoring of the infection. In resource-poor settings such as the study locality, identifying affordable biomarkers for disease management is important. This study was a case-control analytical single-site research among people living with H

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Ndrepepa, Gjin, Stefan Holdenrieder, and Adnan Kastrati. "Prognostic value of De Ritis ratio in patients with acute myocardial infarction." Clinica Chimica Acta 535 (October 2022): 75–81. http://dx.doi.org/10.1016/j.cca.2022.08.016.

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Yilmaz, Mehmet, Yusuf Sahin, Huseyin A. Ates, Ibrahim Hacibey, and Gokhan Cil. "De Ritis ratio: how effectively can we use in bladder cancer management?" Biomarkers in Medicine 14, no. 15 (2020): 1453–60. http://dx.doi.org/10.2217/bmm-2020-0212.

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Background: This study aims to determine the relationship between the pre-operative De Ritis ratio (DRR) and bladder cancer (BCa) pathological subtypes. Results & methodology: A total of 248 patients with primary BCa were included. Univariate and multivariate analyses were performed to identify whether DRR can be a risk factor for the presence of carcinoma in situ (C IS). There was a statistically significant difference between the nonmuscle invasive BCa risk groups and the muscle-invasive BCa group according to the median DRR levels (p < 0.001). DRR was an independent risk factor for t

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Karamık, Kaan, Yasin Aktaş, Ali Yıldız, et al. "Predictive Role of De Ritis Ratio in Biochemical Recurrence After Radical Prostatectomy." Medical Bulletin of Haseki 58, no. 1 (2020): 84–93. http://dx.doi.org/10.4274/haseki.galenos.2019.5592.

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Guner, Ekrem, Kamil Gokhan Seker, Yusuf Arikan, Coshgun Huseynov, Emre Sam, and Ozdem Levent Ozdal. "The utility of De Ritis Ratio in predicting prognosis in testicular cancer." Aktuelle Urologie 51, no. 03 (2020): e2-e2. http://dx.doi.org/10.1055/a-1150-1965.

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Shvydkov, A. N., O. I. Sebezhko, A. I. Kalmykova, et al. "Assessment of the influence of the metabolitic probiotic Biosib METAPRO on protein metabolism indicators in broiler chickens." Vestnik of the Russian agricultural science, no. 6 (December 26, 2024): 89–96. https://doi.org/10.31857/s2500208224060194.

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The paper presents data on the study of the influence of the metabolic probiotic (metaprobiotic) Biosib METAPRO, developed based on a complex of cultures Bifidobacterium longum and Lactobacillus plantarum at LLC “Sibbiopharm”, on the indicators of protein metabolism in broiler chickens. The study was conducted on Ross 308 cross chickens from 6 days to 35 days of age, using four groups: control and three experimental groups, to which Biosib METAPRO was additionally administered in different doses. The quantitative assessment of protein metabolism indicators in the blood serum of birds was perfo

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Eriksson, Victoria, Oscar Holmkvist, Ylva Huge, et al. "A Retrospective Analysis of the De Ritis Ratio in Muscle Invasive Bladder Cancer, with Focus on Tumor Response and Long-Term Survival in Patients Receiving Neoadjuvant Chemotherapy and in Chemo Naïve Cystectomy Patients—A Study of a Clinical Multicentre Database." Journal of Personalized Medicine 12, no. 11 (2022): 1769. http://dx.doi.org/10.3390/jpm12111769.

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Background: A high pre-treatment De Ritis ratio, the aspartate transaminase/alanine aminotransferase ratio, has been suggested to be of prognostic value for mortality in muscle-invasive bladder cancer (MIBC). Our purpose was to evaluate if a high ratio was associated with mortality and downstaging. Methods: A total of 347 Swedish patients with clinically staged T2-T4aN0M0, with administered neoadjuvant chemotherapy (NAC) or eligible for NAC and undergoing radical cystectomy (RC) 2009–2021, were retrospectively evaluated with a low ratio < 1.3 vs. high ratio > 1.3, by Log Rank test, Cox r

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Kim, Jina, Hye In Lee, In Ah Kim, et al. "719: De Ritis ratio in elderly glioblastoma patients treated with temozolomide-based chemoradiation." Radiotherapy and Oncology 194 (May 2024): S780—S782. http://dx.doi.org/10.1016/s0167-8140(24)01267-2.

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Tsai, Ching-Hua, Ting-Min Hsieh, Shiun-Yuan Hsu, and Ching-Hua Hsieh. "A High De Ritis Ratio is Associated with Mortality in Adult Trauma Patients." Risk Management and Healthcare Policy Volume 16 (May 2023): 879–87. http://dx.doi.org/10.2147/rmhp.s409345.

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Gójska-Zygner, Olga, Justyna Karabowicz, Justyna Bartosik, and Wojciech Zygner. "Association between Increased the De Ritis Quotient and Renal Azotaemia in Canine Babesiosis." Animals 12, no. 5 (2022): 626. http://dx.doi.org/10.3390/ani12050626.

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Previous studies of azotaemia in canine babesiosis revealed pre-renal and renal azotaemia in infected dogs, and an association between an increased de Ritis quotient (aspartate aminotransferase to alanine aminotransferase activity; AST/ALT ratio) and azotaemia in affected animals. Serum activities of AST and ALT, and AST/ALT ratio were compared between azotaemic and non-azotaemic dogs infected with Babesia canis, and between affected dogs with pre-renal and renal azotaemia. Statistical analyses revealed higher AST activity and an increased AST/ALT ratio in azotaemic dogs, and an increase of th

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Galler, Markus, Julian M. M. Rogasch, Kai Huang, et al. "Prognostic Value of the Largest Lesion Size for Progression-Free Survival in Patients with NET Undergoing Salvage PRRT with [177Lu]Lu-DOTATOC." Cancers 14, no. 7 (2022): 1768. http://dx.doi.org/10.3390/cancers14071768.

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(1) Background: retreatment with radionuclide-labeled somatostatin analogues following disease progression after initial treatment cycles is often referred to as salvage peptide receptor radionuclide therapy (salvage PRRT). Salvage PRRT is shown to have a favorable safety profile in patients with metastatic neuroendocrine tumors (NETs), but numerous questions about the efficacy and prognostic or predictive factors remain to be answered. The purpose of this study was to evaluate two parameters that have shown prognostic significance in progression-free survival (PFS) in initial PRRT treatment,

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