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Journal articles on the topic 'Decamethoxinum'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Nazarchuk, A. A., S. V. Vernygorodskyi, V. G. Palii, and G. G. Nazarchuk. "Experimental Reseach of Effectiveness of Antimicrobial Surgical Matherials Containing Decamethoxinum." Novosti Khirurgii 26, no. 1 (2018): 16–23. http://dx.doi.org/10.18484/2305-0047.2018.1.16.

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2

Derkach, N. M., and Z. S. Suvorova. "The antimicrobial action of decamethoxinum substance at different pH values." Vìsnik farmacìï, no. 4(88) (December 21, 2016): 70–75. http://dx.doi.org/10.24959/nphj.16.2142.

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3

Nazarchuk, O. A., and D. V. Paliy. "SUBSTANTIATION OF OVERCOMING OF ANTIBIOTIC RESISTANCE IN ACINETOBACTER BAUMANNII CLINICAL STRAINS BY USAGE OF DECAMETHOXINUM." Annals of Mechnikov Institute, no. 2 (June 7, 2017): 28–33. https://doi.org/10.5281/zenodo.803858.

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<strong>Introduction</strong>. Non-fermenting Gram-negative bacilli are known as one of the most frequent causative agents of hospital-acquired infections. <em>Acinetobacter</em> <em>baumanii</em>, as causative agent of infection complications of different localization, has obtained recently high resistance to antibiotics and has belonged to ESKAPE group of pathogens. Antimicrobials, recommended for the prophylaxis ant therapy of hospital-acquired infections, have been failing in their effectiveness and lead to selection of antibiotic resistant strains of <em>A</em><em>. </em><em>baumanii</em>

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4

Nazarchuk, O. A., and V. I. Nahaichuk. "Antibiotic resistance in Acinetobacter baumannii as agent of surgery infection and approaches to its overcoming by means of deca-methoxinum antiseptic." Perioperaciina Medicina 1, no. 2 (2019): 18–22. http://dx.doi.org/10.31636/prmd.v1i2.2.

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Introduction. Non-fermenting Gram-negative bacilli are known as one of the most frequent causative agents of hospital-acquired infections. Acinetobacter baumannii, as causative agent of infection complications of different localization, has obtained recently high resistance to anti-biotics and has belonged to ESKAPE group of pathogens. Antimicrobials, recommended for the prophylaxis and therapy of hospital-acquired infections, have been failing in their effectiveness and lead to selection of antibiotic resistant strains of A. baumannii. The aim of this research was to substantiate the wa

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5

Pashynska, V. A., M. V. Kosevich, H. Van den Heuvel, and M. Claeys. "The effect of cone voltage on electrospray mass spectra of the bisquaternary ammonium salt decamethoxinum." Rapid Communications in Mass Spectrometry 20, no. 5 (2006): 755–63. http://dx.doi.org/10.1002/rcm.2371.

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6

Kazakova, O. O., N. O. Lipkovska, and V. M. Barvinchenko. "Spectral and quantum-chemical investigation of interactions in supra-molecular systems: cucumin - decametoxin - silica in aqueous solutions." SURFACE 14(29) (December 30, 2022): 221–30. http://dx.doi.org/10.15407/surface.2022.14.221.

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The peculiarities of the interaction in the supramolecular system: the natural hydrophobic polyphenol curcumin - the antiseptic cationic surface-active substance decamethoxin - highly dispersed silica was revealed by the spectrophotometric method. It was established that significant changes in the spectral characteristics of curcumin in aqueous solutions and on the surface of the sorbent depend on the concentration of this cationic surfactant, which can exist in the solution in the form of monomers, associates, and micelles. The PM7 method and the COSMO solvation model, implemented in the MOPA

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7

Дзюблик, І. В., О. П. Трохименко, С. О. Соловйов, В. В. Трохимчук, О. Л. Боророва, and О. К. Яковенко. "Efficacy decametoxin in vitro for quick inactivation of respiratory coronavirus." Farmatsevtychnyi zhurnal, no. 2 (April 25, 2022): 87–101. http://dx.doi.org/10.32352/0367-3057.2.22.09.

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Despite the fact that specific prophylaxis agents have already been widely introduced into medical practice in all countries of the world, and antiviral drugs are being developed and are undergoing the first stages of clinical trials, SARS-CoV-2 continues to spread in the human population. In this regard, an urgent medical problem today is the expansion of the arsenal of effective disinfectants and antiseptics, the action of which would be aimed at the rapid and complete inactivation of extracellular coronavirus, which is a very important element in controlling the spread of COVID-19. Th

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Pashynska, Vlada A., Marina V. Kosevich, Agnes Gömöry, Zoltan Szilágyi, Karoly Vékey, and Stepan G. Stepanian. "On the stability of the organic dication of the bisquaternary ammonium salt decamethoxinum under liquid secondary ion mass spectrometry." Rapid Communications in Mass Spectrometry 19, no. 6 (2005): 785–97. http://dx.doi.org/10.1002/rcm.1846.

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9

Bagnyuk, N. A., O. A. Nazarchuk, Y. M. Babina, R. M. Chornopyshchuk, and A. V. Kulyk. "Antimicrobial activity of antiseptics in the prevention of postoperative infectious complications." Biomedical and Biosocial Anthropology, no. 40 (November 27, 2021): 33–36. http://dx.doi.org/10.31393/bba40-2020-05.

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Recently, among hospital strains of microorganisms, an increase in the number of antiseptic-resistant strains of opportunistic pathogens has been registered, which significantly affects the effectiveness of these drugs. It is important to study their antimicrobial efficacy to justify rational use. The aim is to conduct a comparative study of the antimicrobial efficacy of antiseptics of decamethoxine, chlorhexidine, polyhexanide. During study we examined the antimicrobial activity against 186 clinical strains of microorganisms (Acinetobacter baumannii, Staphylococcus aureus, Pseudomonas aerugin

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10

Nazarchuk, Oleksandr. "Research of antimicrobial efficacy of modern antiseptic agents based on decamethoxine and povidone-iodine." Perioperaciina Medicina 2, no. 1 (2019): 6–10. http://dx.doi.org/10.31636/prmd.v2i1.1.

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Under conditions of wide increased resistance of pathogens of infectious complications to antimicrobial agents, a considerable attention is paid to the use of antiseptic drugs. The research of their antimicrobial efficacy remains valid for substantiation of the rational use. The purpose was to carry out a comparative study of the antimicrobial efficacy of medicinal antiseptic agents based on decamethoxine and povidone-iodine. In the study there was examined antimicrobial activity of mentioned antiseptics against 682 clinical strains of microorganisms (A. baumannii, S. aureus, P. aerugino

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11

Nazarchuk, Oleksandr, and Tetyana Denysko. "Evaluation of antimicrobial activity of biomaterials based on alginate and decametoxin against Staphylococus aureus and Escherichia coli." ScienceRise: Biological Science, no. 4(37) (December 29, 2023): 11–18. http://dx.doi.org/10.15587/2519-8025.2023.298594.

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The aim was to study the antimicrobial activity of new biomaterials based on decamethoxine and commercially available wound dressings against reference and clinical strains of S.aureus and E.coli. Materials and methods. Developed biomaterials with 0.05 % decamethoxine (DCM No. 1-3) and wound dressings containing antiseptics Suprasorb®, SILVERCEL®, Urgotul SSD®, GUANPOLISEPT®, Bétadine® were used for the study. Antimicrobial properties were studied by zone of inhibition (ZOI) testing using the Kirby-Bauer method. Results. In relation to S.aureus ATCC 25923, a significantly higher antimicrobial

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Ostrovsky, M. M., O. I. Varunkiv, and K. V. Shvets. "Possibilities of Using Decametoxin in Patients with Chronic Diseases of the Lower Respiratory Tract with Acute Respiratory Viral Infections." Asthma and allergy 2023, no. 4 (2023): 13–20. http://dx.doi.org/10.31655/2307-3373-2023-4-13-20.

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The annual increase in the number of patients with chronic respiratory diseases and a significant increase in the level of antibiotic resistance in Ukraine and in the world has set modern scientists an extremely important task - the search for new effective ways of combating infectious agents of viral and bacterial exacerbations of pathologies of the tracheobronchial tree. The aim: to assess the efficacy and safety of decamethoxine in patients with exacerbations of chronic obstructive pulmonary disease (COPD) and chronic bronchitis (CB). Materials and methods: clinical symptoms were evaluated

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13

Kucherenko, L. I., O. O. Chonka, and O. O. Portna. "Development of methods for standardization of the active substance, namely the model mixture based on decamethoxine and thiotriazoline." Zaporozhye Medical Journal 23, no. 5 (2021): 703–7. http://dx.doi.org/10.14739/2310-1210.2021.5.225459.

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Today, the important problem is the creation of new decamethoxine and thiotriazoline based drugs for the treatment of stomatitis. The aim of the work is to develop a method for quantitative determination of decamethoxine and thiotriazoline in the model mixture (1:25) by spectrophotometry. Materials and methods. Series 6 model mixtures were made at the ratio of decamethoxine and thiotriazoline 1:25. We used certified substances: thiotriazoline series GTT 3460911 (manufacturer: State Enterprise Chemical Reagents Plant, Kharkiv), decamethoxine series № 010915 (manufacturer: LLC “PHARMCHIM”). Opti

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Kucherenko, Ludmila, Svetlana Shishkina та Elena Chonka. "Theoretical study of the possibility of decamethoxin complexes with thiotriazolinе to be formed". ScienceRise: Pharmaceutical Science, № 4(32) (31 серпня 2021): 37–42. http://dx.doi.org/10.15587/2519-4852.2021.239279.

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Over the last decade, much attention has been paid to the prevention and treatment of chronic diseases of the oral mucosa. This is primarily due to the increase in the number of patients who seek dental care for diseases of the oral mucosa (DOM). Currently, due to the lack of special epidemiological studies, information on the pathology of the oral mucosa in the literature is almost non-existent. The etiology and pathogenesis have not been definitively elucidated. It is established that a significant role in the pathogenesis of chronic inflammatory processes belongs to the state of

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15

Ludmila, Kucherenko, Shishkina Svetlana та Chonka Elena. "Theoretical study of the possibility of decamethoxin complexes with thiotriazolinе to be formed". ScienceRise: Pharmaceutical Science, № 4(32) (31 серпня 2021): 37–42. https://doi.org/10.15587/2519-4852.2021.239279.

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Over the last decade, much attention has been paid to the prevention and treatment of chronic diseases of the oral mucosa. This is primarily due to the increase in the number of patients who seek dental care for diseases of the oral mucosa (DOM). Currently, due to the lack of special epidemiological studies, information on the pathology of the oral mucosa in the literature is almost non-existent. The etiology and pathogenesis have not been definitively elucidated. It is established that a significant role in the pathogenesis of chronic inflammatory processes belongs to the state of the microbi

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16

Khimich, O. S. "Microbiological study of the influence of an immunomodulator on the antimicrobial activity of the decametoxin antiseptic agent with their combined application." Reports of Vinnytsia National Medical University 28, no. 1 (2024): 12–16. http://dx.doi.org/10.31393/reports-vnmedical-2024-28(1)-02.

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Annotation. The article presents the results of a microbiological study of the immunomodulator “Blastomunyl” on the antimicrobial activity of the antiseptic decamethoxine in combined use. A microbiological study of the antimicrobial activity of decamethoxine in the presence of different contents of blastomunil was carried out by the macromethod of serial dilutions: sample 1 – contained 0.6 mg of blastomunil in 4 ml of decamethoxine solution, sample 2 – contained 0.6 mg of blastomunil in 8 ml of decamethoxine solution, sample 3 – 0, 6 mg of blastomunil in 10 ml of decamethoxine solution. The an

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17

Lipkovska, N. O., and V. M. Barvinchenko. "Effect of supromolecular interactions with cationic surfactant decamethoxine on adsorption of curcumine on highly dispersed silica." Himia, Fizika ta Tehnologia Poverhni 13, no. 3 (2022): 311–20. http://dx.doi.org/10.15407/hftp13.03.311.

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Curcumin, a sparingly soluble polyphenol of plant origin, has antitumor, anti-inflammatory, antithrombotic, antidiabetic and antimicrobial properties. Currently, an important task is the development of medicinal composites based on curcumin, which provide an increase in its solubility and, accordingly, bioavailability. The aim of the work is to determine the optimal conditions for the adsorption of curcumin on the surface of a silica enterosorbent as soluble supramolecular complexes with a cationic dimeric surfactant decamethoxine. The UV/Vis spectroscopy data indicate that supramolecular inte

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18

Nazarchuk, Oleksandr A., Ihor L. Chereshniuk, and Halyna H. Nazarchuk. "THE RESEARCH OF ANTIMICROBIAL EFFICACY OF ANTISEPTICS DECAMETHOXIN, MIRAMISTIN AND THEIR EFFECT ON NUCLEAR DNA FRAGMENTATION AND EPITHELIAL CELL CYCLE." Wiadomości Lekarskie 72, no. 3 (2019): 374–80. http://dx.doi.org/10.36740/wlek201903111.

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Introduction: Nowadays, the study of biological safety of modern cationic surface-active antiseptics with a wide antimicrobial spectrum has acquired particular importance. The aim was to study antimicrobial effectiveness of antiseptics decamethoxin, miramistin and their influence on nuclear DNA fragmentation and cellular cycle. Materials and methods: A comparative microbiological study of antimicrobial efficacy and a cytometric study of the effect of decamethoxin 0,02% and miramistin 0,01% on the cellular cycle were carried out. Antimicrobial activity of decamethoxin and miramistin was estimat

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Davtyan, L. L., D. V. Reva, O. V. Chubenko, and V. V. Trohumchuk. "Development of techniques to identify and determine the active ingredient in dental gel composition." Farmatsevtychnyi zhurnal, no. 2 (August 14, 2018): 48–52. http://dx.doi.org/10.32352/0367-3057.2.16.03.

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The technique of the qualitative and quantitative determination of active substances – decamethoxine and lidocaine hydrochloride in a new combination drug for preventing and treating inflammatory diseases of the oral cavity was developed.The aim of the work was to develop a methodology to identify and determine the active pharmaceutical ingredient in the composition of the dental gel.The objects were specimens of the developed dental gel containing lidocaine hydrochloride and decamethoxine. The study was conducted using high performance liquid chromatography (HPLC).The conditions for HPLC chro

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20

Semenyuta, I. V., O. P. Trokhimenko, I. V. Dziublyk, et al. "Decamethoxin virucidal activity: in vitro and in silico studies." Ukrainian Biochemical Journal 94, no. 3 (2022): 81–91. http://dx.doi.org/10.15407/ubj94.03.081.

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The data on the representative of decamethoxin short-term action on infectious bronchitis virus (IBV) strain H120 used as a human-safe model of SARS-CoV-2 virus are presented. The viral activity was estimated with the use of inverted microscope PrimoVert (Germany) by destructive effect on BHK21 fibroblastic cell line. In vitro results demonstrated that decamethoxin (100 μg/ml) completely inactivated IBV coronavirus strain at exposure of 30 sec and more. At the lowest decamethoxin exposure of 10 sec the antiseptic virucidal activity was 33% and 36% of control at 24 and 48 h of cultivation respe

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Khimich, O. S., A. P. Korol, S. D. Khimich, and V. I. Pivtorak. "Morphological assessment of the dynamics of changes in the wound process when using Blastomunil and Decametoxin in an experiment." Reports of Vinnytsia National Medical University 28, no. 2 (2024): 196–203. http://dx.doi.org/10.31393/reports-vnmedical-2024-28(2)-03.

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Annotation. The purpose of the study: to carry out a morphological assessment of the effectiveness of the use of the immunomodulator Blastomunil in combination with Decamethoxine in the treatment of infected wounds in an experiment. The topicality of the topic is determined by the search for new medicinal forms for the treatment of infected wounds. At the same time, morphological assessment of the course of the wound process is extremely important. A study was conducted on 40 rats (4 groups of animals, 10 in each). An infected wound was made on the back of all animals under anesthesia. 1 group

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22

Halushko, Oleksandr. "A clinical view on the possibility and feasibility of using decamethoxin during the COVID-19 pandemic." Perioperaciina Medicina 4, no. 1 (2021): 30–38. http://dx.doi.org/10.31636/prmd.v4i1.5.

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Background. Due to the significant spread of the COVID-19 pandemic and the available contact route of transmission, there is a growing interest in the possibility of using antiseptics to prevent contagion of this viral disease. However, the list of antiseptic drugs for local application is limited. The aim: to investigate the possibility and feasibility of clinical use of decamethoxine as an antiseptic during the infectious COVID-19 pandemic. Materials and methods. Researches and systematic reviews published between 2001 and 2020 were studied using PubMed and Google Scholar searche

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Savitsky, I. V., S. V. Tsypovyaz, R. G. Zashchuk, R. G. Lenik, and S. G. Znamerovsky. "Study of endothelin-1 dynamics in the pathogenesis of experimental peritonitis and under the influence of different methods of correction." Perioperaciina Medicina 5, no. 1 (2022): 49–53. http://dx.doi.org/10.31636/prmd.v5i1.6.

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Background. Currently, one of the most serious complications of acute inflammatory diseases of the abdominal cavity is peritonitis. Objective: to study the development of endothelial dysfunction in experimental peritonitis and compare its correction with a solution of decamethoxine, aminoguadine and L-arginine. Materials and methods of research. The study was conducted on 260 white rats of reproductive age (3 months), animal weight — 180–220 g. Animals were divided into 4 groups. Fecal peritonitis was simulated by introducing a 10 % fecal suspension at a dose of 0.5 ml per 100 g of anima

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Kucherenko, L. I., I. F. Belenichev, О. О. Chonka, Z. B. Moryak, and O. Gylevskaya. "THE INFLUENCE OF SUBLINGUAL TABLETS OF THIOTRIAZOLIN AND DECAMETHOXIN ON ALLERGY MARKERS AND TOXICITY INDICATORS." Biological Markers in Fundamental and Clinical Medicine (collection of abstracts) 4, no. 2 (2020): 29–33. http://dx.doi.org/10.29256/v.04.02.2020.escbm06.

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Nazarchuk, O. A., V. I. Nahaichuk, O. V. Rymsha, et al. "Research of antimicrobial efficacy of a composition with prolonged antiseptic effect against planktonic and film forms of clinical strains of non-fermentative Gram-negative bacteria." Reports of Vinnytsia National Medical University 24, no. 1 (2020): 64–68. http://dx.doi.org/10.31393/reports-vnmedical-2020-24(1)-12.

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Annotation. The problem of treatment of burn wounds is closely related to the specificity of the spectrum of microorganisms that impair wound healing in this category of patients. A generally alarming trend in recent years is the significant increase in the etiological structure of wound infection, both in frequency and in severity and in the difficult choice of treatment tactics in the isolation of poly antimicrobial resistant strains of Pseudomonas aeruginosa, Acinetobacter baumannii. The aim of our study was to create a model of biofilm formed by bacteria on the wound surface and to investi

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Іщенко, О. В., В. І. Бессарабов, В. П. Плаван, О. П. Баула, І. В. Ресницький та С. С. Черкас. "ДОСЛІДЖЕННЯ КІНЕТИКИ ВИВІЛЬНЕННЯ АНТИМІКРОБНОГО ПРЕПАРАТУ ДЕКАМЕТОКСИНУ В ПОЛІМЕРНИХ ПЛІВКАХ МЕДИЧНОГО ПРИЗНАЧЕННЯ". Bulletin of the Kyiv National University of Technologies and Design. Technical Science Series 128, № 6 (2019): 86–94. http://dx.doi.org/10.30857/1813-6796.2018.6.10.

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The main purpose of this work was to investigate the kinetics of releasing of the antiseptic drug decamethoxin from polymeric films to determine the ability of their use in the composition of transdermal therapeutic systems. Methodology. Polymeric films containing polyvinyl alcohol, modified starch, glycerol and antiseptic drug decamethoxin were used in the investigation. For dissolution, water of grade 3 of purity was used. Control of the dissolution samples and the construction of the calibration graphic for DCM was performed spectrophotometrically on the OPTIZEN POP UV VIS device ("Mecasys"

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Bororova, O. L. "Efficacy and safety of decamethoxin in complex treatment of patients with group III viral-bacterial community-acquired pneumonia." Infusion & Chemotherapy, no. 1 (March 25, 2021): 15–21. http://dx.doi.org/10.32902/2663-0338-2021-1-15-21.

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BACKGROUND. There are many unsolved medical problems and, of course, pneumonia is one of them. Communityacquired pneumonia (CAP) is a multifactorial disease, but the role of viruses as causative agents is constantly growing. Specific antiviral therapy for CAP is limited. Therefore, the search for drugs with virucidal activity remains relevant. An antimicrobial agent with a broad spectrum of action – decamethoxin – is successfully used today for treatment of patients with infectious exacerbations of bronchial asthma and chronic bronchitis. At the same time efficacy of decamethoxin in CAP patien

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Trofimenko, Y. Y., E. F. Makac, O. K. Stucan, and V. M. Burkot. "Sensitivity of biofilm and planktonic forms of non-fermenting bacteria to the action of antiseptics." Reports of Vinnytsia National Medical University 22, no. 2 (2018): 293–96. http://dx.doi.org/10.31393/reports-vnmedical-2018-22(2)-12.

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It is known that bacteria colonize endotracheal intubation tubes [EIT], form biofilms. Bacterial cells that are in the film matrix are protected from the effects of external factors and differ in high levels of resistance to the action of antibiotics, antiseptics, and disinfectants. The purpose of our study was to determine the sensitivity of the antiseptics of biofilm and planktont forms of non-fermentable gram-negative bacteria to the action of the antiseptics of decamethoxin, chlorohexidine bigluconate, povidone iodine, hydrogen peroxide. In order to create bacterial biofilms, sterile fragm

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Nagaichuk, Vasyl, Roman Chornopyshchuk, Igor Gerashchenko, Olena Kukolevska, and Anatolie Sidorenko. "Experimental Substantiation of Antimicrobial Efficiency of a New Composite Polymeric Material Based on Poly(2-Hydroxyethyl Methacrylate) under the Action of Low-Intensity Current without External Power Supplies." Materials Science Forum 1038 (July 13, 2021): 154–61. http://dx.doi.org/10.4028/www.scientific.net/msf.1038.154.

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Active use of polymeric materials has become an integral part of all areas of modern medicine. Wound dressings capable of prolonged release of drugs directly into the lesion occupy a special place among them. The possibility of using such materials in the presence of low-intensity currents without external power supplies in a comprehensive treatment program for patients with burn injuries remains promising. The aim of the work is to study experimentally the antimicrobial efficacy of a new composite polymeric material based on poly(2-hydroxyethyl methacrylate), saturated with the antiseptic dec

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Соломенний, А. М., and А. О. Дроздова. "Theoretical and experimental substantiation of receiving a pharmaceutical composition in the form of a cryogel with lidocain hydrochloride and decametoxin." Farmatsevtychnyi zhurnal, no. 1 (February 27, 2023): 66–74. http://dx.doi.org/10.32352/0367-3057.1.23.07.

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Modern medicines for the treatment of wounds are developed on the basis of knowledge about their phase healing. The main principle of wound treatment is the creation and maintenance of a moist environment, stable temperature, absorption of excess exudate, minimization of the risk of sensitization, increased intervals between dressings, easy removal of coatings from the surface of the wound. The implementation of this principle is the basis of our research on the creation of a cryogel – a supermacroporous hydrogel that is formed at subzero temperatures by polymerization of monomers or cryogel f

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Solomennyi, Andrii. "STUDY OF THE QUALITY COMPOSITION OF MODERN WOUND-HEALING AGENTS BASED ON DECAMETOXIN AND METHYLURACIL." SWorld-Ger Conference proceedings, gec25-01 (February 28, 2020): 44–50. http://dx.doi.org/10.30890/2709-1783.2023-25-01-024.

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The author has substantiated the concentration of methyluracil (in vivo) and decamethoxine (in vitro) for the development of the composition, technology, and biopharmaceutical research of an antimicrobial and wound-healing ointment with methyluracil, deca

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Gumeniuk, M. I., O. V. Denysova, G. L. Gumeniuk, S. G. Opimakh, and V. I. Ignatieva. "DECAMETHOXIN: NEBULIZER THERAPY OF INFECTIOUS EXACERBATION OF CHRONIC BRONCHITIS." Asthma and allergy 2019, no. 3 (2019): 17–28. http://dx.doi.org/10.31655/2307-3373-2019-3-17-28.

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Ishchenko, Olena, Olha Sumska, Kateryna Smykalo, Yuliia Feshchuk, and Daria Kuchynska. "ANTIMICROBIAL APPROACHES FOR TEXTILES." TECHNICAL SCIENCES AND TECHNOLOGIES, no. 4(34) (2023): 115–28. http://dx.doi.org/10.25140/2411-5363-2023-4(34)-115-128.

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The use of textile materials with antimicrobial treatment is one of the ways to effectively protect a person from exposure to various pathogens. The article is devoted to the topical issue of the development of innovative textile materials with prolonged antimicrobial treatment. To establish the possibility and features of obtaining innovative textile materials with long-term antimicrobial treatment. To prepare this article, many materials were considered, as well as ready-made solutions that were publicly available.Despite the fact that research on this topic was conducted, in order to obtain

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Nahaichuk, Vasyl, Oleksandr Nazarchuk, Roman Chornopyshchuk, Pavlo Hormash, and Yuliana Babina. "Peculiarities of the wound healing process in the acute period of burn disease depending on the antiseptic used." Perioperaciina Medicina 2, no. 2 (2019): 14–22. http://dx.doi.org/10.31636/prmd.v2i2.3.

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Background. Burn injury, as one of the most common types of trauma, requires a comprehensive approach to treatment, including surgical and conservative treatment with effective post-burn wound protection. One of the main obstacles to wound healing is purulent-infectious complications, for prevention of which antiseptics are widely used. The aim is to study the microbiological, histological features of the wound healing course in the acute period of burn disease with the use of various antiseptics. Materials and methods. In the research there were involved 44 patients with burns (bu

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Nazarchuk, A. A., T. V. Denisko, N. I. Voloshchuk, and H. H. Nazarchuk. "The study of antimicrobial properties of film materials based on biopolymers and antiseptics." Biomedical and Biosocial Anthropology, no. 39 (October 29, 2020): 29–34. http://dx.doi.org/10.31393/bba39-2020-05.

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The development of new biomaterials with improved properties is becoming increasingly important in a wide range of applications. However, some of the most sought-after properties are anti-microbial properties, which can help prevent unwanted wound infections, especially in the face of growing antibiotic resistance of bacteria. The aim of the study was to study the effect of antimicrobial biomaterials based on calcium alginate, as a polymer system of local prolonged delivery of quaternary ammonium compounds, on reference and clinical strains of microorganisms. Samples of antimicrobial biomateri

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Paliy, V. G., O. A. Nazarchuk, D. V. Paliy, and K. I. Iakovets. "Substantiation of medical use of antimicrobial remedies, containing decamethoxin®." Bukovinian Medical Herald 21, no. 1 (81) (2017): 100–105. http://dx.doi.org/10.24061/2413-0737.xxi.1.81.2017.21.

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Gonchar, O. O., O. A. Nazarchuk, D. V. Paliy, I. V. Kovalenko, and O. V. Yatsula. "Study of antimicrobial qualities of antiseptic remedies, which contain decamethoxin." Ukraïns’kij bìofarmacevtičnij žurnal, no. 1(42) (February 4, 2016): 74–77. http://dx.doi.org/10.24959/ubphj.16.15.

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Hlaholieva, Anastasiia. "Comparison of the effectiveness of preventive systemic administration of antibiotics with topical use of decamethoxin during clean surgical interventions." Perioperaciina Medicina 2, no. 2 (2019): 8–13. http://dx.doi.org/10.31636/prmd.v2i12.2.

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Introduction. The lack of generally accepted standards of perioperative antimicrobial prophylaxis leads to the inadequate preventive use of antibiotics associated with development of microbial resistance, changes in the natural biota and sensitization of the patient’s body. Prevention of infectious complications after surgery with topical antiseptic is an appropriate alternative to antibiotic prophylaxis. The purpose of this study was to evaluate the efficacy and safety of topical antiseptic prophylaxis of infectious complications with a 0.02 % decamethoxin solution compared to systemic antibi

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Trofimenko, Y. Y., O. I. Zhorniak, N. S. Fomina, V. M. Burkot, A. V. Kulik, and P. V. Zhorniak. "Study of the effectiveness of using decamethoxin-based antiseptic compositions for treating endotracheal tubes in order to prevent the development of ventilator-associated pneumonia in intensive care patients." Reports of Vinnytsia National Medical University 24, no. 1 (2020): 17–19. http://dx.doi.org/10.31393/reports-vnmedical-2020-24(1)-03.

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Annotation. The use of artificial lung ventilation in patients of intensive care unit often leads to airway contamination of conditionally pathogenic microorganisms and the development of ventilator-associated pneumonia. The clinical manifestations of ventilator-associated pneumonia can vary widely from mild to development of critical conditions accompanied by septic shock. This significantly worsens the patient's condition and prognosis for effective treatment. The paper presents the results of the study of the use of adhesive antiseptic compositions based on the domestic antiseptic drug deca

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Musaev, A. I., and K. K. Kenzhekulov. "Experience of treatment of purulent wounds using ozonated solutions and decamethoxin solution." Kazan medical journal 97, no. 4 (2016): 651–56. http://dx.doi.org/10.17750/kmj2015-651.

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Aim. To evaluate the effectiveness of using ozonated solutions combined with decamethoxin solution in the treatment of purulent wounds.Methods. 101 patients with purulent wounds were under observation. In the treatment of all patients, the first stage was surgical debridement, which removes exudate and non-viable tissue. Also the conditions for wound drainage and good drainage of wound exudate were created, and then the treatment of wounds under a bandage was performed. In the main group (51 people) in addition to the basic treatment ozonated 0.9% sodium chloride solution with a concentration

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Slobodianyk, S. V., S. D. Khimich, S. V. Vernygorodskyi, and V. S. Shkolnikov. "Morphological rationale of mesenchymal stem cells in the local treatment of experimental chronic purulent-necrotic wounds." Pathologia 19, no. 1 (2022): 70–78. http://dx.doi.org/10.14739/2310-1237.2022.1.247230.

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Aim: to study morphological changes in healing of chronic purulent-necrotic wounds in rats with local use of 0.025 % decamethoxine solution and mesenchymal stem cells. Materials and methods. The experimental study was performed on 120 rats, which were divided into the following groups: I – control (without treatment); II – the use of classical wound healing (0.025 % decamethoxine); III – the use of clones of mesenchymal stem cells from the umbilical cord; IV – the use of clones of mesenchymal stem cells (cloned in inert gases). To assess morphological changes in chronic wounds, fragments measu

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Gumeniuk,, M. I., S. G. Opimakh, G. L. Gumeniuk, and V. I. Ignatieva. "DECAMETHOXINE: THE OPTION IN TREATMENT OF PATIENTS WITH ASTHMA INFECTIOUS EXACERBATIONS." Ukrainian Pulmonology Journal 104, no. 2 (2019): 25–32. http://dx.doi.org/10.31215/2306-4927-2019-104-2-25-32.

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Vovk, I. M., N. V. Kryvetska, V. M. Burkot, A. O. Dudar, and A. V. Kulik. "Microbiological grounds for antimicrobial treatment of experimental pseudomonal keratitis." Reports of Vinnytsia National Medical University 24, no. 1 (2020): 114–17. http://dx.doi.org/10.31393/reports-vnmedical-2020-24(1)-21.

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Annotation. In the structure of the corneal microbial diseases bacterial keratitis take second rate position after viral keratitis. They are characterized by a severe course and often leads to complications that require surgical treatment. P. aeruginosa is the main causative agent of keratitis associated with the contact lenses wearing. The aim of our work was to check up the combined action of fluoroquinolones, tobramycin and antiseptic decamethoxine on clinical strains of P. aeruginosa in vitro with microbiological methods. The studies were performed on clinical strains of P. aeruginosa, whi

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Faustova, M. O., O. A. Nazarchuk, H. A. Loban, et al. "Influence of anti-microbial composition based on calcium alginate on museum strains of microorganisms." Reports of Vinnytsia National Medical University 24, no. 1 (2020): 118–21. http://dx.doi.org/10.31393/reports-vnmedical-2020-24(1)-22.

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Annotation. In the context of antibiotic resistance development, the search for the new biologically active substances for the prevention and Treatment of Infectious Diseases is an important part of pharmaceutical research. The aim of the study was investigating the effect of antimicrobial composition based on calcium alginate on the museum strains of microorganisms. Standard strains of Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Enterococcus faecalis were used for the study. The investigated antimicrobial composition was made up of decamethoxine (0.2–0.5%) and calcium

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Klovak, Viktoriia, and Kulichenko Sergey. "Spectrophotometric and Fluorescent Determination of Hydrophobic Organic Cations in the Surfactant-modified System Mo(VI)– Bromopyrogallol Red." Methods and Objects of Chemical Analysis 18, no. 2 (2023): 55–62. http://dx.doi.org/10.17721/moca.2023.55-62.

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The spectrophotometric and fluorescent characteristics of the surfactant-modified molybdenum (VI) – bromopyrogallol red reagent system were studied. The hydrophobic modification was achieved by adding cationic, nonionic surfactants, or, accordingly, mixtures of surfactant modifiers into the metal reagent system. Modification of the metal reagent system with a nonionic surfactant leads to a decrease in the limit of detection of the hydrophobic organic cation in the molybdenum (VI) – bromopyrogallol red system by the fluorescence method and an increase in the contrast of the spectrophotometric r

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Dziublyk, O. Ya, I. V. Dzyublyk, O. P. Trokhimenko, and O. L. Bororova. "THE VIRUCIDAL EFFECT OF DECAMETHOXIN IN VITRO AGAINST CORONAVIRUS OF INFECTIOUS BRONCHITIS." Ukrainian Pulmonology Journal 108, no. 2 (2020): 27–30. http://dx.doi.org/10.31215/2306-4927-2020-108-2-27-30.

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Nazarchuk, O. A., A. I. Starodub, O. V. Rymsha, V. A. Starodub, and S. A. Kolodii. "Characteristics of the etiological structure and susceptibility to antibiotics, antiseptics of infectious pathogens of respiratory organs in children in critical states." Reports of Vinnytsia National Medical University 22, no. 2 (2018): 311–17. http://dx.doi.org/10.31393/reports-vnmedical-2018-22(2)-16.

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The study of the etiological structure, the properties of pathogens of the respiratory infectious diseases in children and their resistance to antibacterial agents is particularly relevant in modern conditions, expands the search for new approaches to combating pathogens, improves the results of treatment and reduces the mortality of this pathology. The aim — study of etiological structure, sensitivity to antibiotics and antiseptics of pathogens of infectious and inflammatory diseases of respiratory organs in children. In the study there were enrolled 247 patients who were treated in Vinnytsia

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Bezhuk, Yu A., and O. I. Martovlos (Hodovana). "IMPACT OF A GEL COMPOSITION CONTAINING VARIOUS SUBSTANCES ON INDICES OF IMMUNITY AND TISSUE INFLAMMATION IN PALATINE TONSILS OF PATIENTS WITH CATARRHAL GINGIVITIS DURING CHRONIC TONSILLITIS." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 24, no. 1 (2024): 78–83. http://dx.doi.org/10.31718/2077-1096.24.1.78.

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The study of pharmacotherapeutic (immunomodulating) action in conditions of in vitro cell cultures is currently considered appropriate and justified for determining the action of drugs at the preclinical level. It is also important to address the pathogenetic nature in using such agents, especially fro local application. This study investigated the efficacy of a multicomponent gel containing decamethoxine and hyaluronic acid in treating chronic catarrhal gingivitis among patients with chronic tonsillitis. The purpose of the work is to assess the efficacy of a gel containing decamethoxine and h

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Nazarchuk, O. A., M. O. Faustova, V. V. Bobyr, and Yu V. Kordon. "The investigation of the relationship between biofilm-forming properties of clinical strains of p.aeruginosa and their sensitivity to antiseptic medicines." Reports of Vinnytsia National Medical University 22, no. 3 (2018): 403–6. http://dx.doi.org/10.31393/reports-vnmedical-2018-22(3)-01.

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High antimicrobial properties of antiseptics determine the scientific interest in the study of their effect on the biofilm formation of clinically significant pathogens and the detection of a probable dependence between the sensitivity of bacteria to them and the ability to form biofilms. The aim — was to study the biofilm-forming properties of clinical strains of P.aeruginosa, depending on their sensitivity to various antiseptic medicines. 30 clinical strains of P.aeruginosa were isolated and identified from the patients with infectious complications of different areas who had been treated at

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Paliy, G. K., S. V. Pavliuk, A. O. Dudar, D. V. Paliy, and A. V. Kulyk. "Characteristics of the resistance of microorganisms to antimicrobial drugs." Reports of Vinnytsia National Medical University 22, no. 3 (2018): 417–21. http://dx.doi.org/10.31393/reports-vnmedical-2018-22(3)-04.

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The resistance of microorganisms to antimicrobial drugs is an important problem of medicine. The aim – to study forming of the resistance to decamethoxine® (DCM®), decaminum (DC) and properties of microorganisms. In the study, a quantitative assessment of antimicrobial drugs was performed based on the activity index of the drug (AID), which shows the ratio of the working concentration of antiseptic to its minimum active concentration for a specific agent. The first indicator for determining the AID is derived from the instructions for the use of the drug, the relevant directories. Minimum inac

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