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1

Tucker, Hannah L. "Extracellular Proteoglycan Decorin in Bovine Mammary Physiology." Diss., Virginia Tech, 2017. http://hdl.handle.net/10919/79430.

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The majority of bovine mammary gland research focuses on the main cell types - mammary epithelial cells and fibroblasts. However, the extracellular matrix (ECM) within the mammary gland is also of importance for its ability to regulate cell shape, proliferation, polarity, differentiation, gene transcription, protein synthesis, and secretion. Decorin is an ECM proteoglycan known to impact mammary cell proliferation in humans and rodents. Prior to this work, very little was known about decorin in bovine mammary biology. A series of bovine mammary cell culture experiments was conducted. The first
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Didraga, Mihaela Alina. "Analytical approaches towards structural characterization of human lung decorin a comparative study of decorin from control and emphysematous lungs /." [S.l. : [Groningen : s.n.] ; University Library Groningen] [Host], 2008. http://irs.ub.rug.nl/ppn/.

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3

Fust, Anita. "Lung mechanics in mice : effect of decorin deficiency." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=80268.

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Decorin is required for the normal fibrillogenesis and spatial arrangement of collagen. As collagen is important in determining the elastic behaviour of the lung, we hypothesized that lung tissue mechanics would be altered in decorin deficient (Dcn-/-) mice. Complex impedance, pressure-volume curves, and length-stress curves of lung parenchyma were measured in C57BL/6 mice, 6 Dcn-/- and 6 wildtype ( Dcn+/+), both in vivo and in vitro. Immunohistochemistry and Western blotting were performed to identify decorin and biglycan in the lung tissues. In vivo, airway resistance was decreased an
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4

Marchica, Cinzia Loreta 1984. "Allergen-induced asthma is decreased in decorin-deficient mice." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116096.

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Decorin, is an extracellular matrix proteoglycan with important biological functions. Decorin deficiency affects collagen fibrillogenesis, airway mechanics, airway-parenchymal interdependence, and airway smooth muscle proliferation and apoptosis. We questioned whether decorin deficiency would alter allergen-induced asthma in a mouse model. Decorin-/- and decorin+/+ mice (C57Bl/6) were sensitized and challenged with ovalbumin. Control animals received saline. Responsiveness was assessed at baseline and after delivery of increasing concentrations of methacholine. Histological analyses were also
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Fiedler, Lorna. "Role of decorin in control of endothelial cell behaviour." Thesis, Cardiff University, 2007. http://orca.cf.ac.uk/55666/.

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Angiogenesis is a complex process regulated by co-ordination of extracellular matrix (ECM) and growth factor signalling (via integrins and growth factor receptors respectively). Dysregulated angiogenesis contributes to disease pathology and progression, while an adequate blood supply is crucial for successful tissue repair and reconstruction. Thus an understanding of the mechanisms by which ECM controls angiogenesis would contribute to development of therapeutic strategies. Decorin is a small leucine-rich repeat proteoglycan consisting of a core protein and a single glycosaminoglycan. Decorin
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6

Vieira, Sofia Daniela Peixoto. "Decorar a minha escola: tecnologias informáticas e padrões geométricos." Master's thesis, Universidade de Aveiro, 2010. http://hdl.handle.net/10773/3554.

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Mestrado em Multimédia em Educação<br>O contacto com as tecnologias informáticas começa desde tenra idade quando os brinquedos se tornam cada vez mais tecnológicos e passam a ser parte integrante da vida das crianças. A escola tem, por isso, o dever de integrar as tecnologias nas suas práticas logo nos primeiros anos escolares permitindo, assim, o desenvolvimento de competências essenciais nesta e outras áreas, tanto mais que essa integração beneficia o processo de ensino e de aprendizagem. As tecnologias podem funcionar como forte aliado na construção do conhecimento. Não obstante a sua impo
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Strazynski, Marco. "Induktion der Decorin-Synthese in Endothelzellen durch Wechselwirkung mit Fibroblasten." [S.l. : s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969065841.

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8

Brown, Andrew S. "Two-dimensional Polyacrylamide Gel Electrophoresis (2D-PAGE) Characterization of Decorin." Youngstown State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1311873768.

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9

Soares, Leila Cristina. "Composição da matriz extracelular do ligamento cardinal de mulheres na pós-menopausa com e sem prolapso uterino." Universidade do Estado do Rio de Janeiro, 2011. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=2497.

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O prolapso uterino tem sua incidência aumentada na pós-menopausa. O objetivo deste estudo é identificar as alterações na matriz extracelular do ligamento cardinal associadas à menopausa e ao prolapso uterino. Ligamento cardinal de três diferentes grupos de mulheres, pré-menopausa, prolapso uterino e pós-menopausa, foram identificados e biopsiados durante 57 histerectomias abdominais ou vaginais. As amostras foram processadas por métodos bioquímicos para caracterização e quantificação de glicosaminoglicanos sulfatados e colágeno. As concentrações relativas de glicosaminoglicanos foram obtidas p
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10

Dorken, Marcel Eric. "The loss of sex in a highly clonal plant, Decodon verticillatus, Lythraceae." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ28192.pdf.

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11

Islam, Mehwaesh. "Biochemical analysis of collagen binding by invertebrate SPARC and engineered monomeric decorin." Thesis, Imperial College London, 2013. http://hdl.handle.net/10044/1/24664.

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Collagens are a family of extracellular matrix proteins that are critically important for providing structural support to tissues and for regulating cell behaviour. The thesis describes the biochemical analysis of collagen binding by two globular proteins that profoundly influence collagen fibril formation in vivo, decorin and SPARC. Decorin is the archetypal small leucine-rich repeat proteoglycan and an important regulator of collagen fibrillogenesis. The crystal structure of decorin, published in 2004, revealed a dimeric structure in which the presumed collagen binding site was not accessibl
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Ribeiro, Bruno Leonardo Marroig de Freitas. "Análise imunohistoquímica dos proteoglicanossindecan, decorin e biglican na próstata normal e hiperplásica." Universidade do Estado do Rio de Janeiro, 2011. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=9080.

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Os mecanismos celulares envolvidos na hiperplasia prostática benigna (HPB) não são bem compreendidos e pouco se sabe sobre como os proteoglicanos estão relacionados com esta condição. Neste estudo foi avaliada a expressão de proteoglicanos de superfície celular e do estroma na HPB. As amostras de próstata com HPB foram colhidas de pacientes submetidos à prostatectomia aberta e ressecção transuretral da próstata (RTUP), enquanto as amostras do grupo controle consistiram na zona de transição de próstatas normais de adultos jovens. Foram usados anticorpos primários anti-sindecan-1, anti-biglican
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Federico, Stefania. "Synthetic peptides derived from decorin as building blocks for biomaterials based on supramolecular interactions." Phd thesis, Universität Potsdam, 2011. http://opus.kobv.de/ubp/volltexte/2012/5966/.

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In this work, the development of a new molecular building block, based on synthetic peptides derived from decorin, is presented. These peptides represent a promising basis for the design of polymer-based biomaterials that mimic the ECM on a molecular level and exploit specific biological recognition for technical applications. Multiple sequence alignments of the internal repeats of decorin that formed the inner and outer surface of the arch-shaped protein were used to develop consensus sequences. These sequences contained conserved sequence motifs that are likely to be related to structural an
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Kamara, Kandeh. "Effect of ectopic expression of decorin in a leukemic cell line engineered to express TAL1 and LMO1 proteins." Virtual Press, 2003. http://liblink.bsu.edu/uhtbin/catkey/1273268.

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Progress in understanding cancer progression has been hampered over the years by the different types of mutations present and irregular changes of gene regulation associated with any given cancer. In this work, molecular interactions between TALI, LMO1, and decorin were investigated. Numerous studies have shown that ectopic expression of decorin protein induced growth suppression in neoplastic cells of various histogenic origins. Furthermore, ectopic expression of TAL1 and LMOI oncoproteins has been shown to occur in approximately 50% of the cases of T-cell acute lymphoblastic leukemia (T-ALL)
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Adam, Marion. "Regulation and functional signaling of decorin in the testis in health and disease." Diss., lmu, 2011. http://nbn-resolving.de/urn:nbn:de:bvb:19-136659.

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Sayani, Karim Nurali. "In situ hybridization for decorin and transforming growth factor-ß1 mRNA in hypertrophic scar." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/mq22668.pdf.

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17

Da, Silva Elizabeth M. "Pollinator-mediated impacts of the invasive plant species Lythrum salicaria on the native Decodon verticillatus." Thesis, University of Ottawa (Canada), 2010. http://hdl.handle.net/10393/28910.

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Plant-pollinator interactions in invaded communities can range from facilitative to competitive, with the latter being most commonly observed. If invasive species can successfully integrate into native plant-pollinator networks and change pollinator foraging patterns, native plant fitness in these communities could be altered. Here I examine the impact of the showy flowering invasive plant, purple loosestrife (Lythrum salicaria), on a co-flowering close relative, swamp loosestrife (Decodon verticillatus). Both species are in the family Lythraceae, share a number of floral traits, and tend to b
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18

D'Antoni, Michelle. "The effect of decorin and biglycan on human airway smooth muscle cell proliferation, apoptosis and attachment." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=103624.

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Changes in extracellular matrix (ECM) deposition along with increases in airway smooth muscle (ASM) mass are characteristic features of airway remodeling which contribute to asthma pathophysiology. Modifications in ECM include increased collagen deposition and altered proteoglycans (PGs) levels. While biglycan, a small leucine-rich PG (SLRP), deposition is generally increased, changes in decorin, another SLRP, are more variable. The interaction between the cell and the surrounding ECM triggers numerous cellular responses, which modulate functions such as survival, proliferation and differen
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19

Shope, Suzanne Alene. "American Indian artist, Angel Decora aesthetics, power, and transcultural pedagogy in the progressive era /." Diss., [Missoula, Mont.] : University of Montana, 2009. http://etd.lib.umt.edu/theses/available/etd-10132009-112300.

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Schneider, Magdalena [Verfasser], and Rudolf [Akademischer Betreuer] Fuchshofer. "The Role of Decorin in the Pathogenesis of Primary Open Angle Glaucoma / Magdalena Schneider ; Betreuer: Rudolf Fuchshofer." Regensburg : Universitätsbibliothek Regensburg, 2017. http://d-nb.info/1149366486/34.

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21

Meinerz, Giovani Volnei. "DECOLA : um modelo de decisões colaborativas para sequenciamentos de pousos e decolagens utilizando sistemas multiagentes." Instituto Tecnológico de Aeronáutica, 2011. http://www.bd.bibl.ita.br/tde_busca/arquivo.php?codArquivo=1971.

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A infraestrutura do sistema de transporte aéreo brasileiro e mundial vem sofrendo nos últimos anos pressão contínua e crescente, devido às grandes solicitações a que é submetida. Este cenário pode levar setores de ATC em Áreas de Controle Terminal, TMA, a condições de congestionamento e saturação. Diante da limitada capacidade de expansão dos recursos de infraestrutura, as alternativas de solução encontram-se voltadas para a necessidade de melhoria das atividades de Gerenciamento de Fluxo de Tráfego Aéreo, ATFM, envolvendo a fase de planejamento pré-tática e a forma de ATM pró-ativa. Neste se
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Benedetto, Monique Saveriano de. "\"Expressões dos proteoglicanos biglican e decorin na matriz extracelular em dentes decíduos humanos durante o processo de rizólise\"." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/23/23132/tde-17042007-145522/.

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As proteínas são importantes componentes da matriz extracelular da polpa dentária e possuem diferentes funções nos tecidos. A literatura odontológica não relata como os proteoglicanos se distribuem e agem na matriz extracelular de dentes decíduos durante o processo fisiológico de rizólise. Foi objetivo do trabalho analisar as expressões dos proteoglicanos biglican e decorin e relacioná-las com as diversas fases do processo de rizólise. Para isso foram utilizados dentes decíduos humanos extraídos e livres de lesões de cárie, apresentando vários estágios de reabsorção radicular, divididos em trê
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23

Adam, Marion [Verfasser], and Lars [Akademischer Betreuer] Kunz. "Regulation and functional signaling of decorin in the testis in health and disease / Marion Adam. Betreuer: Lars Kunz." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2011. http://d-nb.info/1017688222/34.

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Federico, Stefania [Verfasser], and Andreas [Akademischer Betreuer] Lendlein. "Synthetic peptides derived from decorin as building blocks for biomaterials based on supramolecular interactions / Stefania Federico. Betreuer: Andreas Lendlein." Potsdam : Universitätsbibliothek der Universität Potsdam, 2012. http://d-nb.info/1022489267/34.

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Holásková, Ida. "I. Distribution of transforming growth factor beta 1, TGF receptor II and decorin in the sheep uterus shortly after breeding." Morgantown, W. Va. : [West Virginia University Libraries], 2007. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=5373.

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Thesis (Ph. D.)--West Virginia University, 2007.<br>Title from document title page. Document formatted into pages; contains ix, 144 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 126-144).
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Jones, David Lee. "Distributional Ecology of Coral Reef Fish Larvae (Labridae, Scaridae) in the Southern Straits of Florida." Scholarly Repository, 2008. http://scholarlyrepository.miami.edu/oa_dissertations/28.

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This study targets the poorly described egg and larval stages of wrasses and parrotfishes that as adults inhabit coral reefs and seagrasses in the western central Atlantic. Descriptions are provided to allow laboratory identification of the egg and larval stages of these fishes. Accounts are given for 16 of the 20 species of labrid and six of the 14 species of scarids that occur here. The biological, hydrographic, and meteorological data from four oceanographic surveys of the southern Straits of Florida were analyzed to provide a synthesis of the effects of the environment on the distribution
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Esmaeili, Maryam. "Development and characterisation of systems for the delivery of an antiscarring molecule (decorin) for use after corneal injury and cutaneous burn." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8387/.

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Introduction: Transforming growth factor-β1 (TGF-β1) is a key cytokine that promotes fibrosis after injury in many adult tissues. Here, we hypothesise that delivery of human recombinant decorin (hr-decorin), a natural antagonist of TGF-β1, loaded into gellan-based biomembrane sheet dressings and fluid gel eye drops, prevents cutaneous and corneal scarring after injury. Methods: Gellan-based wound dressings loaded with hr-decorin were characterised for swelling, release profile of hr-decorin, systemic absorption of hr-decorin and human skin reactions. Topical gellan-based fluid gels loaded with
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Burk, Janina, Claudia Gittel, Sandra Heller, et al. "Gene expression of tendon markers in mesenchymal stromal cells derived from different sources." Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-157823.

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Background: Multipotent mesenchymal stromal cells (MSC) can be recovered from a variety of tissues in the body. Yet, their functional properties were shown to vary depending on tissue origin. While MSC have emerged as a favoured cell type for tendon regenerative therapies, very little is known about the influence of the MSC source on their properties relevant to tendon regeneration. The aim of this study was to assess and compare the expression of tendon extracellular matrix proteins and tendon differentiation markers in MSC derived from different sources as well as in native tendon tissue. MS
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El, Shafey Nelly. "Evaluation de peptides régulateurs positifs de la masse musculaire." Thesis, Paris 5, 2014. http://www.theses.fr/2014PA05S012.

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La myostatine est un membre de la superfamille du TGF-β (transforming growth factor-β) impliqué dans la régulation négative de la masse musculaire. En effet, l’absence de myostatine (MSTN) chez la souris est responsable d’un phénotype hypermusclé. Depuis, il a été confirmé qu’une baisse de l’activité de la MSTN conduit à une augmentation de la masse musculaire chez d’autres espèces, y compris l’Homme. L’identification de la MSTN et des conséquences de son invalidation sur le développement musculaire ouvre de nombreuses perspectives en médecine humaine. Il existe de nombreuses situations pathol
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Nilsson, Annevi, and Josefine Sjögren. "Liberty tetra : - Ett eldrivet rullstolstillbehör för personer med tetraplegi." Thesis, Högskolan i Halmstad, Akademin för ekonomi, teknik och naturvetenskap, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-36906.

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Arbetet är gjort tillsammans med rullstolshjälpmedelsföretaget Decon Wheel som ville utveckla en av sina produkter, Liberty, så att den kan manövreras av personer med tetraplegi. Tetraplegi betyder att det har skett en skada på ryggmärgen så högt upp att 4 extremiteter, överkropp, bål, bäcken och ben, har blivit skadade och helt eller delvis förlorat sin funktion. Det togs fram ett antal lösningsförslag på hur styrningen, inklusive gas- och bromsreglage kunde utformas så att kraven i kravspecifikationen uppnåddes och det bästa konceptet togs vidare i arbetet. Syftet var att ta fram ett styr-,
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Marty-Roix, Robyn Lynn. "T Cells Aid in Limiting Pathogen Burden and in Enhancing B1 and B2 Cell Antibody Responses to Membrane Glycolipid and the Surface Lipoprotein Decorin-Binding Protein A during Borrelia burgdorferi Infection: A Dissertation." eScholarship@UMMS, 2010. http://escholarship.umassmed.edu/gsbs_diss/498.

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Murine infection by the Lyme disease spirochete, B. burgdorferi, results in the generation of pathogen-specific antibody that can provide protection against Lyme disease, but the cells involved in this response are poorly characterized. T cells are not required for generating a protective antibody response to B. burgdorferi infection, but their exact role in providing protection against tissue colonization had not been previously determined. We found that TCRβxδ;-/- mice were susceptible to high pathogen loads and decreased antibody titers, but inhibition of CD40L-dependent interactions result
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Hendricksen, David A. "Twentieth-century choral music programming by Concordia, Luther, and St. Olaf college choirs, 1950-1986." Virtual Press, 1988. http://liblink.bsu.edu/uhtbin/catkey/558362.

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This dissertation complements those analytical studies which discuss choral works and techniques of contemporary choral composition, by examining what twentieth-century literature was actually performed within one of the choral traditions of the United States.The a cappella choral tradition has spread widely throughout the United States. Previous studies have examined the history of the pioneering a cappella choirs and the biographies of the movement's leaders. This study also complements them in examining another aspect of the a cappella tradition.Three representative choirs were chosen: the
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Lust, Caitlyn. "Women’s Work: Re-evaluating the Canon of Graphic Design History." Ohio University Honors Tutorial College / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ouhonors1556273078639679.

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Editorial, Comité. "Grupo de expertos peruanos demanda una nueva política para la hoja de coca." Pontificia Universidad Católica del Perú, 2012. http://repositorio.pucp.edu.pe/index/handle/123456789/79712.

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Borbely, Alexandre Urban. "Expressão de pequenos proteoglicanos ricos em leucina: decorim e biglicam, em placentas humanas a termo normais e com alterações da invasividade trofoblástica." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/42/42134/tde-09112009-123700/.

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O decorim e o biglicam são membros da família dos pequenos proteoglicanos ricos em leucina e possuem importantes funções no controle da proliferação, migração e invasão do citotrofoblasto extraviloso (TEV). O objetivo deste trabalho foi de caracterizar a expressão diferencial e a imunolocalização de decorim e biglicam em placentas humanas normais a termo (PNT), na placenta acreta (PA), na mola invasora (MI) e no coriocarcinoma (CO). Na PNT, as células deciduais apresentaram positividade para o decorim, enquanto o TEV foi negativo. O decorim foi fracamente expresso na matriz endometrial, mas ne
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Cherfan, Julien. "La décorine : un nouveau composant de la communication entre les muscles squelettiques et les cellules β pancréatiques". Electronic Thesis or Diss., Strasbourg, 2019. http://www.theses.fr/2019STRAJ066.

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Le diabète de type 2 est une pathologie chronique en augmentation galopante à travers le monde. Une alimentation trop riche combinée à une sédentarité conduit à une hyperglycémie chez les patients au cours du temps. L’augmentation de la masse corporelle de ces sujets induit une inflammation chronique. Ce phénomène perturbe à terme la physiologie de la cellule β pancréatique en provoquant la perte de sa fonction sécrétrice d’insuline et en réduisant la masse des îlots pancréatiques, conduisant à une insulino-dépendance, dernier stade du diabète de type 2. Le dialogue inter-organe, dit le « cros
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POLITO, UMBERTO. "THE MENISCUS: BASIC SCIENCE TO IMPROVE KNOWLEDGE FOR TISSUE ENGINEERING." Doctoral thesis, Università degli Studi di Milano, 2020. http://hdl.handle.net/2434/707236.

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This thesis was thought with the intent to try to fill some lacunae in the knowledge of the anatomic-dependent features of the meniscus. In particular, the study of the effects of endogenous and exogenous factors upon the development of this structure will be outlined. Endogenous factors have been considered those factors that cannot be attributed to external or experimental factors: the effect of age and growth has been investigated focusing on the variation of the, matrix components (collagen types, GAGs and decorin), cellular phenotypic modifications and meniscal morpho-functional structure
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Bhide, Vinay M. "Decorin-induced inhibition of collagen phagocytosis by fibroblasts." 2005. http://link.library.utoronto.ca/eir/EIRdetail.cfm?Resources__ID=370188&T=F.

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Walter, Sven Christian. "Molekulargenetische Untersuchungen am Decorin-Gen bei verschiedenen Formen des Ehlers-Danlos-Syndrom /." 2004. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=013073440&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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Bryan, John A. "Enrofloxacin induced changes in decorin production by equine tendon explants in culture." 2009. http://purl.galileo.usg.edu/uga%5Fetd/bryan%5Fjohn%5Fa%5F200905%5Fms.

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Thiel, Stephan Rücker Thomas. "Materialflusssteuerung eines heterogenen Produktionssystems am Beispiel der Decoma Carplast GmbH /." 2007. http://www.gbv.de/dms/ilmenau/abs/537945954thiel.txt.

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Strazynski, Marco [Verfasser]. "Induktion der Decorin-Synthese in Endothelzellen durch Wechselwirkung mit Fibroblasten / vorgelegt von Marco Strazynski." 2003. http://d-nb.info/969065841/34.

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Emerson, Norlene René. "Sedimentology, sequence stratigraphy, and brachiopod biostratigraphy of the Ordovician (Mohawkian) Decorah Formation, midcontinent, USA." 2002. http://www.library.wisc.edu/databases/connect/dissertations.html.

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"Identification of Structural Mechanisms that Modulate Glycosaminoglycan Affinity in Various Strains of Decorin Binding Protein A." Doctoral diss., 2015. http://hdl.handle.net/2286/R.I.34887.

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abstract: Glycosaminoglycans (GAGs) are a class of complex biomolecules comprised of linear, sulfated polysaccharides whose presence on cell surfaces and in the extracellular matrix involve them in many physiological phenomena as well as in interactions with pathogenic microbes. Decorin binding protein A (DBPA), a Borrelia surface lipoprotein involved in the infectivity of Lyme disease, is responsible for binding GAGs found on decorin, a small proteoglycan present in the extracellular matrix. Different DBPA strains have notable sequence heterogeneity that results in varying levels of GAG-bindi
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Seitz, Stefan Fischäder Holm. "Erarbeitung eines Konzepts zum Aufzeigen logistischer Verbesserungspotenziale bei Re-Allokation Produkt-Standort der Decoma Trim /." 2006. http://www.gbv.de/dms/ilmenau/abs/509307353seitz.txt.

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46

Alnoury, Arwa. "Effects of a synthetic peptide derived from collagen binding domain of decorin on matrix metalloproteinase (MMP)-mediated collagen degradation." Thesis, 2018. https://hdl.handle.net/2144/32949.

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Abstract:
Decorin is the most characterized member of Small Leucine-Rich Repeat Proteoglycan (SLRP) family. It has been previously shown that some SLRP members including decorin bind to collagen type I. Binding of decorin to collagen was reported to inhibit collagen degradation by collagenases, suggesting that decorin might limit the access of collagenases to their collagen cleavage site. The amino acid sequence SYIRIADTNIT in decorin was reported to be the binding region to collagen type I. The objective of the current study was to investigate the effect of the synthetic SYIRIADTNIT peptide derived fro
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Failing, Katja Anna [Verfasser]. "Decorin und α1-Kollagen-IX-Doppel-Knockout-Mäuse [Alpha1-Kollagen-IX-Doppel-Knockout-Mäuse] / vorgelegt von: Katja Anna Failing geb. Dickerhof". 2003. http://d-nb.info/968379834/34.

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48

"Sialidase L, a novel NeuAc(alpha)2--3Gal-specific sialidase from the leech, Macrobdella decora: Purification, characterization, cloning and expression." Tulane University, 1996.

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Sialidase L releases 2,7-anhydro-NeuAc from sialoglyco-conjugates (Li, Y. -T. Nakagawa, H., Ross, S. A., Hansson, G., and Li, S. -C. (1990) J. Biol. Chem. 265, 21629-21633). This enzyme has been purified from Macrobdella leeches. The final preparation gives a single protein band on SDS-PAGE with a molecular mass of 84 kDa. The pI is determined to be 6.0 using isoelectric focusing. With 4-methylumbelliferyl-$\alpha$-NeuAc as substrate, the pH optimum is between pH 5.5 and 7.0. Unlike regular sialidases, sialidase L is not inhibited by 2-deoxy-2,3-dehydro-NeuAc. Among various sialoglycoconjugate
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Coch, Christoph [Verfasser]. "Screening auf Interaktionspartner für den hämatologischen Rezeptor PRV-1 : PRV-1 interagiert mit Decorin, C1qB und Defensin-alpha-3 / vorgelegt von Christoph Coch." 2006. http://d-nb.info/980205514/34.

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Tiede, Karen [Verfasser]. "Kardiale Expression der Proteoglykane Biglykan und Decorin : Untersuchungen an kultivierten Fibroblasten neonataler Ratten und an infarzierten Herzen adulter Ratten / vorgelegt von Karen Tiede." 2002. http://d-nb.info/972249753/34.

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