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Journal articles on the topic 'Decoy liposomes'

Author: Grafiati

Published: 4 June 2021

Last updated: 16 February 2022

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1

Ayllon, Marcelo, Gamid Abatchev, Andrew Bogard, Rosey Whiting, Sarah E. Hobdey, and Daniel Fologea. "Liposomes Prevent In Vitro Hemolysis Induced by Streptolysin O and Lysenin." Membranes 11, no. 5 (2021): 364. http://dx.doi.org/10.3390/membranes11050364.

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The need for alternatives to antibiotics in the fight against infectious diseases has inspired scientists to focus on antivirulence factors instead of the microorganisms themselves. In this respect, prior work indicates that tiny, enclosed bilayer lipid membranes (liposomes) have the potential to compete with cellular targets for toxin binding, hence preventing their biological attack and aiding with their clearance. The effectiveness of liposomes as decoy targets depends on their availability in the host and how rapidly they are cleared from the circulation. Although liposome PEGylation may i

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2

Hendricks, Gabriel L., Lourdes Velazquez, Serena Pham, et al. "Heparin octasaccharide decoy liposomes inhibit replication of multiple viruses." Antiviral Research 116 (April 2015): 34–44. http://dx.doi.org/10.1016/j.antiviral.2015.01.008.

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3

Buchanan, Kyle D., Shao-Ling Huang, Hyunggun Kim, David D. McPherson та Robert C. MacDonald. "Encapsulation of NF-κB decoy oligonucleotides within echogenic liposomes and ultrasound-triggered release". Journal of Controlled Release 141, № 2 (2010): 193–98. http://dx.doi.org/10.1016/j.jconrel.2009.09.017.

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4

Tomita, Naruya, Masatsugu Horiuchi, Sawako Tomita, et al. "An oligonucleotide decoy for transcription factor E2F inhibits mesangial cell proliferation in vitro." American Journal of Physiology-Renal Physiology 275, no. 2 (1998): F278—F284. http://dx.doi.org/10.1152/ajprenal.1998.275.2.f278.

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The transcription factor E2F controls expression of several genes involved in cell proliferation including c- myc, c- myb, proliferating cell nuclear antigen (PCNA), and cdk2 kinase. Having established that both PCNA and cdk2 kinase are induced in rat mesangial cells (MC) by serum stimulation, we attempted to inhibit MC proliferation in vitro by transfecting these cells with cationic liposomes containing a synthetic double-stranded oligodeoxynucleotide (ODN) with high affinity for E2F. Using a gel mobility shift assay, we detected increased specific binding of E2F in MC following serum stimula

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5

Buchanan, Kyle D., ShaoLing Huang, Susan D. Tiukinhoy-Laing, David D. McPherson, and Robert C. MacDonald. "1024. Encapsulation of the NF-kB Decoy Oligonucleotide in Echogenic Liposomes and Its Ultrasound-Triggered Release." Molecular Therapy 13 (2006): S394. http://dx.doi.org/10.1016/j.ymthe.2006.08.1119.

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6

Borgatti, Monica, Laura Breda, Rita Cortesi та ін. "Cationic liposomes as delivery systems for double-stranded PNA–DNA chimeras exhibiting decoy activity against NF-κB transcription factors". Biochemical Pharmacology 64, № 4 (2002): 609–16. http://dx.doi.org/10.1016/s0006-2952(02)01188-7.

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7

Kraus, Damian, M. Edward Medof, and Carolyn Mold. "Complementary Recognition of Alternative Pathway Activators by Decay-Accelerating Factor and Factor H." Infection and Immunity 66, no. 2 (1998): 399–405. http://dx.doi.org/10.1128/iai.66.2.399-405.1998.

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ABSTRACT The alternative complement pathway (ACP) functions as a surveillance mechanism by which microorganisms are opsonized with C3b in the absence of specific antibodies. The effectiveness of the ACP relies on its ability to distinguish self from non-self. This recognition function is mediated by C3 regulatory proteins including serum factor H, membrane cofactor protein (MCP), and membrane decay-accelerating factor (DAF). H activity against bound C3b can be increased by host components such as sialic acid and decreased by microbial polysaccharides. DAF and MCP may also recognize cell surfac

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8

Pilch, Ewa, and Witold Musiał. "Selected Physicochemical Properties of Lyophilized Hydrogel with Liposomal Fraction of Calcium Dobesilate." Materials 11, no. 11 (2018): 2143. http://dx.doi.org/10.3390/ma11112143.

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Lyophilization is the process of drying and improving the stability of various pharmaceutical preparations. In this work we evaluated the properties of 11 hydrophilic gels calcium dobesilate with liposomes based on soybean lecithin, subjected to the freeze-drying procedure. Liposomes were produced by using method thin lipid film. Lyophilization was carried out under conditions of temperature equal (−30 °C) and pressure 0.37 mbar. We evaluated the preparations with dynamic light scattering (DLS) method, optical microscopy and Fourier-transform infrared spectroscopy (FTIR). In this work we prese

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9

Gabrielska, Janina, and Jan Oszmiański. "Antioxidant Activity of Anthocyanin Glycoside Derivatives Evaluated by the Inhibition of Liposome Oxidation." Zeitschrift für Naturforschung C 60, no. 5-6 (2005): 399–407. http://dx.doi.org/10.1515/znc-2005-5-606.

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Cyanidin-3-glycosides (arabinoside, rutinoside, galactoside and glucoside) and delphinidin- 3-rutinoside were examined for their ability to inhibit lipid peroxidation induced either by Fe(II) ions, UV irradiation or 2,2′-azobis(2-amidinopropane) dihydrochloride (AAPH) peroxyl radicals in a liposomal membrane system. The antioxidant abilities of anthocyanins were compared with a water-soluble tocopherol derivative, trolox. The antioxidant efficacies of these compounds were evaluated by their ability to inhibit the fluorescence intensity decay of the extrinsic probe 3-[p-(6-phenyl)-1,3,5,-hexatr

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10

Ramasamy, Thiruganesh, Xucai Chen, Bin Qin, Daniel E. Johnson, Jennifer R. Grandis, and Flordeliza S. Villanueva. "STAT3 decoy oligonucleotide-carrying microbubbles with pulsed ultrasound for enhanced therapeutic effect in head and neck tumors." PLOS ONE 15, no. 11 (2020): e0242264. http://dx.doi.org/10.1371/journal.pone.0242264.

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Signal transducer and activator of transcription-3 (STAT3) is an oncogenic transcription factor implicated in carcinogenesis, tumor progression, and drug resistance in head and neck squamous cell carcinoma (HNSCC). A decoy oligonucleotide targeting STAT3 offers a promising anti-tumor strategy, but achieving targeted tumor delivery of the decoy with systemic administration poses a significant challenge. We previously showed the potential for STAT3 decoy-loaded microbubbles, in conjunction with ultrasound targeted microbubble cavitation (UTMC), to decrease tumor growth in murine squamous cell ca

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11

Tado, Motoki, Takayuki Abe, Toshifumi Hatta, et al. "Inhibitory Effect of Modified 5′-Capped Short RNA Fragments on Influenza Virus RNA Polymerase Gene Expression." Antiviral Chemistry and Chemotherapy 12, no. 6 (2001): 353–58. http://dx.doi.org/10.1177/095632020101200605.

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We have shown previously that the 5′-capped short phosphodiester RNA fragments, Cap decoy, (Gm 12 nt) are potent inhibitors of influenza virus RNA polymerase gene expression. Here we investigate the modified capped RNA derivative containing phosphorothioate oligonucleotides (Cap decoy) as a potential influenza virus RNA polymerase inhibitor. The modified 5′-capped short phosphorothioate RNA fragments (Gms 12–15 nt) with the 5′-capped structure (m7GpppGm) were synthesized by T7 RNA polymerase. The 5′-capped short RNA fragments (Gms 12–15 nt) were encapsulated in liposome particulates and tested

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12

CHEN, PEIZHOU, CHRISTOPHER FERENCE, XIUXIU SUN, YING LIN, LIANJIANG TAN, and TIAN ZHONG. "Antimicrobial Efficacy of Liposome-Encapsulated Citral and Its Effect on the Shelf Life of Shatangju Mandarin." Journal of Food Protection 83, no. 8 (2020): 1315–22. http://dx.doi.org/10.4315/jfp-20-115.

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ABSTRACT Liposome-encapsulated citral was prepared by means of a hot homogenization method. The microstructure, particle size, and zeta potential of the capsules were analyzed by transmission electron microscope and dynamic light scattering, respectively, in which the results showed a good dispersion stability of the citral-loaded liposome. In vitro tests showed that liposome-encapsulated citral significantly (P &lt; 0.05) reduced the populations of Escherichia coli, Bacillus subtilis, Staphylococcus aureus, and Penicillium italicum more than free citral. In vivo tests conducted on fresh S

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13

Son, Gakuhei, Yuji Iimuro, Ekihiro Seki, Tadamichi Hirano, Yasufumi Kaneda та Jiro Fujimoto. "Selective inactivation of NF-κB in the liver using NF-κB decoy suppresses CCl4-induced liver injury and fibrosis". American Journal of Physiology-Gastrointestinal and Liver Physiology 293, № 3 (2007): G631—G639. http://dx.doi.org/10.1152/ajpgi.00185.2007.

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Sustained hepatic inflammation induced by various causes can lead to liver fibrosis. Transcription factor NF-κB is important in regulating inflammatory responses, especially in macrophages. We presently investigated whether an NF-κB decoy, a synthetic oligodeoxynucleotide (ODN) imitating the NF-κB binding site, inhibited the inflammatory response after CCl4 intoxication to prevent CCl4-induced hepatic injury and fibrosis. The NF-κB decoy was introduced into livers by injecting the spleens of mice, using a hemagglutinating virus of Japan (HVJ)-liposome method. ODN was transferred mainly to macr

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14

TOMITA, NARUYA, RYUICHI MORISHITA, HUI Y. LAN та ін. "In VivoAdministration of a Nuclear Transcription Factor-κB Decoy Suppresses Experimental Crescentic Glomerulonephritis". Journal of the American Society of Nephrology 11, № 7 (2000): 1244–52. http://dx.doi.org/10.1681/asn.v1171244.

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Abstract. Glomerular expression of cytokines, interleukin-1 (IL-1), and tumor necrosis factor-α (TNF-α), together with leukocytic infiltration, are prominent features in crescentic glomerulonephritis. Because these cytokines are targets for nuclear transcription factor-κB (NF-κB), the use of NF-κB decoy oligodeoxynucleotide (ODN) treatment was evaluated in an experimental disease model. Crescentic glomerulonephritis was induced in primed Wistar rats by injection of sheep antiglomerular basement membrane serum. Thirty minutes after injection, rats were anesthetized and the left kidney was perfu

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15

Nardo, David, and Vincent J. Venditto. "4222 Synthesis and application of cyanuric chloride lipids for peptide presentation." Journal of Clinical and Translational Science 4, s1 (2020): 17. http://dx.doi.org/10.1017/cts.2020.94.

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OBJECTIVES/GOALS: My long-term career objective is to become an established independent researcher focused on understanding and modulating immune responses to biologics in order to enhance their efficacy and understand the underlying mechanisms by which these interact with the immune system. METHODS/STUDY POPULATION: In this study we will evaluate the utility of cyanuric chloride based synthetic lipids in the presentation of peptide epitopes of the gene delivery vector, adeno-associated virus (AAV). The lipopeptide conjugates will be administered to mice via liposomal formulations to assess th

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16

Terpstra, Valeska, and Theo J. C. van Berkel. "Scavenger receptors on liver Kupffer cells mediate the in vivo uptake of oxidatively damaged red blood cells in mice." Blood 95, no. 6 (2000): 2157–63. http://dx.doi.org/10.1182/blood.v95.6.2157.

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Abstract In vitro studies have shown that damaged red cells and apoptotic cells are efficiently phagocytosed by scavenger receptors from macrophages, even under non-opsonizing conditions. Damaged red blood cells are in vivo effectively removed from the blood circulation, but the responsible receptor systems are largely unknown. We used a murine model in which 51Cr-labeled oxidized red blood cells were injected intravenously, and the cellular uptake sites and the potential involvement of scavenger receptors were analyzed. The decay of damaged red cells was rapid (more than 50% removed within 10

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17

Piva, Roberta, Laura del Senno, Elisabetta Lambertini, Letizia Penolazzi, and Claudio Nastruzzi. "Modulation of estrogen receptor gene transcription in breast cancer cells by liposome delivered decoy molecules." Journal of Steroid Biochemistry and Molecular Biology 75, no. 2-3 (2000): 121–28. http://dx.doi.org/10.1016/s0960-0760(00)00181-3.

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18

Wijagkanalan, Wassana, Shigeru Kawakami, Yuriko Higuchi, Fumiyoshi Yamashita та Mitsuru Hashida. "Intratracheally instilled mannosylated cationic liposome/NFκB decoy complexes for effective prevention of LPS-induced lung inflammation". Journal of Controlled Release 149, № 1 (2011): 42–50. http://dx.doi.org/10.1016/j.jconrel.2009.12.016.

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19

Pan, Junliang, Tongyao Liu, Ji-Yun Kim, et al. "Enhanced Efficacy of Recombinant Factor VIII in Non-Covalent Complex with PEGylated Liposome in Hemophilia A Mice." Blood 110, no. 11 (2007): 3149. http://dx.doi.org/10.1182/blood.v110.11.3149.3149.

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Abstract BAY 79-4980, a non-covalent complex of rFVIII (Kogenate® FS) reconstituted in PEGylated Liposome (PEG-Lip) diluent, was reported to double the bleed-free days in severe hemophilia A patients from 7 to 13 days (35 IU/kg) and 6 to 11 days (25 IU/kg), as compared to respectively corresponding doses of rFVIII1. However, in a more recent phase I trial, the FVIII pharmacokinetics (PK) in plasma was virtually identical in patients who received either rFVIII or BAY 79-4980. To understand the mechanism of action of BAY 79-4980, we compared the pharmacological efficacy and PK of BAY 79-4980 to

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20

DEROSA, G., D. STEFANO, V. LAGUARDIA та ін. "Novel cationic liposome formulation for the delivery of an oligonucleotide decoy to NF-κB into activated macrophages". European Journal of Pharmaceutics and Biopharmaceutics 70, № 1 (2008): 7–18. http://dx.doi.org/10.1016/j.ejpb.2008.03.012.

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21

Hendricks, Gabriel L., Kim L. Weirich, Karthik Viswanathan, et al. "Sialylneolacto-N-tetraose c (LSTc)-bearing Liposomal Decoys Capture Influenza A Virus." Journal of Biological Chemistry 288, no. 12 (2013): 8061–73. http://dx.doi.org/10.1074/jbc.m112.437202.

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22

Searle, Geoffrey, Seymour S. Brody, and Arie Van Hoek. "EVIDENCE FOR THE FORMATION OF A CHLOROPHYLL a/ZEAXANTHIN COMPLEX IN LECITHIN LIPOSOMES FROM FLUORESCENCE DECAY KINETICS." Photochemistry and Photobiology 52, no. 2 (1990): 401–7. http://dx.doi.org/10.1111/j.1751-1097.1990.tb04196.x.

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23

Higuchi, Yuriko, Shigeru Kawakami, Fumiyoshi Yamashita та Mitsuru Hashida. "The potential role of fucosylated cationic liposome/NFκB decoy complexes in the treatment of cytokine-related liver disease". Biomaterials 28, № 3 (2007): 532–39. http://dx.doi.org/10.1016/j.biomaterials.2006.08.045.

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24

Huang, Haiying, Fuminori Sakurai, Yuriko Higuchi та ін. "Suppressive effects of sugar-modified cationic liposome/NF-κB decoy complexes on adenovirus vector-induced innate immune responses". Journal of Controlled Release 133, № 2 (2009): 139–45. http://dx.doi.org/10.1016/j.jconrel.2008.09.081.

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25

Kozyra, K. A., J. R. Heldt, G. Gondek, P. Kwiek, and J. Heldt. "Influence of DPPC Liposome Concentration on the Fluorescence Properties of PRODAN and LAURDAN." Zeitschrift für Naturforschung A 59, no. 11 (2004): 809–18. http://dx.doi.org/10.1515/zna-2004-1115.

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Fluorescence spectral features of PRODAN and LAURDAN in phospholipid vesicles of different phase states were investigated. The results indicate that in the liquid crystalline phase the dominant emission results from the charge transfer (CT) excited state, whereas in the gel state of the membrane the emission from the locally excited (LE) state dominates. The fluorescence time studies point out that there are two radiation modes, one starting from only vibrationally relaxed excited states S1(LE)ν ((S1(CT)ν) and the other from a totally thermally equilibrated state S1(LE)EQ (S1(CT)EQ). In accord

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26

Trujillo-Nolasco, Maydelid, Enrique Morales-Avila, Pedro Cruz-Nova, Kattesh V. Katti, and Blanca Ocampo-García. "Nanoradiopharmaceuticals Based on Alpha Emitters: Recent Developments for Medical Applications." Pharmaceutics 13, no. 8 (2021): 1123. http://dx.doi.org/10.3390/pharmaceutics13081123.

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The application of nanotechnology in nuclear medicine offers attractive therapeutic opportunities for the treatment of various diseases, including cancer. Indeed, nanoparticles-conjugated targeted alpha-particle therapy (TAT) would be ideal for localized cell killing due to high linear energy transfer and short ranges of alpha emitters. New approaches in radiolabeling are necessary because chemical radiolabeling techniques are rendered sub-optimal due to the presence of recoil energy generated by alpha decay, which causes chemical bonds to break. This review attempts to cover, in a concise fas

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27

Dinh, Thuy Duong, Yuriko Higuchi, Shigeru Kawakami, Fumiyoshi Yamashita та Mitsuru Hashida. "Evaluation of Osteoclastogenesis via NFκB Decoy/mannosylated Cationic Liposome-Mediated Inhibition of Pro-inflammatory Cytokine Production from Primary Cultured Macrophages". Pharmaceutical Research 28, № 4 (2011): 742–51. http://dx.doi.org/10.1007/s11095-011-0366-0.

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28

Higuchi, Yuriko, Shigeru Kawakami, Machiko Oka, Yoshiyuki Yabe, Fumiyoshi Yamashita та Mitsuru Hashida. "Intravenous administration of mannosylated cationic liposome/NFκB decoy complexes effectively prevent LPS-induced cytokine production in a murine liver failure model". FEBS Letters 580, № 15 (2006): 3706–14. http://dx.doi.org/10.1016/j.febslet.2006.05.059.

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29

Driomina, Elena S., Victor S. Sharov, and Yury A. Vladimirov. "Fe2+-induced lipid peroxidation kinetics in liposomes: The role of surface Fe2+ concentration in switching the reaction from acceleration to decay." Free Radical Biology and Medicine 15, no. 3 (1993): 239–47. http://dx.doi.org/10.1016/0891-5849(93)90070-b.

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30

Cho, W. H., H. T. Kim, J. H. Koo, and I. K. Lee. "Effect of AP-1 Decoy Using Hemagglutinating Virus of Japan-Liposome on the Intimal Hyperplasia of the Autogenous Vein Graft in Mongrel Dogs." Transplantation Proceedings 38, no. 7 (2006): 2161–63. http://dx.doi.org/10.1016/j.transproceed.2006.06.103.

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31

Kawauchi, Motohiro, Jun-ichi Suzuki, Ryuichi Morishita, et al. "Gene Therapy for Attenuating Cardiac Allograft Arteriopathy Using Ex Vivo E2F Decoy Transfection by HVJ-AVE–Liposome Method in Mice and Nonhuman Primates." Circulation Research 87, no. 11 (2000): 1063–68. http://dx.doi.org/10.1161/01.res.87.11.1063.

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32

Duan, Tian-Li, Han Jiao, Guang-Jun He, and Yong-Bin Yan. "Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN)." Cells 9, no. 1 (2020): 162. http://dx.doi.org/10.3390/cells9010162.

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Translation is spatiotemporally regulated and endoplasmic reticulum (ER)-associated mRNAs are generally in efficient translation. It is unclear whether the ER-associated mRNAs are deadenylated or degraded on the ER surface in situ or in the cytosol. Here, we showed that ER possessed active deadenylases, particularly the poly(A)-specific ribonuclease (PARN), in common cell lines and mouse tissues. Consistently, purified recombinant PARN exhibited a strong ability to insert into the Langmuir monolayer and liposome. ER-anchored PARN was found to be able to reshape the poly(A) length profile of th

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33

Zolese, Giovanna, Enrico Gratton, and Giovanna Curatola. "Phosphatidic acid affects structural organization of phosphatidylcholine liposomes. A study of 1,6-diphenyl-1,3,5-hexatriene (DPH) and 1-(4-trimethylammonium-phenyl)-6-phenyl,1,3,5-hexatriene (TMA-DPH) fluorescence decay using distributional analysis." Chemistry and Physics of Lipids 55, no. 1 (1990): 29–39. http://dx.doi.org/10.1016/0009-3084(90)90146-i.

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34

Golubović, Leonardo. "Nonequlibrium Statistical Mechanics of An Ensemble of Vesicles." MRS Proceedings 407 (1995). http://dx.doi.org/10.1557/proc-407-275.

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ABSTRACTWe investigate far-from-equilibrium dynamics of a polydisperse ensemble of vesicles ( such as liposomes). For that purpose, we construct of a Smoluchowsky-type transport equation incorporating vesicle diffusion and the processes of vesicle fusions and fissions. This approach is used to study the time evolution of an initially monodisperse vesicle ensemble and its important quantities such as the internal aqueous, encapsulated volume. We find three stages of the evolution: (i) an early stage during which EV remains nearly constant, followed by (ii) a stage with a rapid decay of the EV,

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35

Lestner, Jodi M., Andreas H. Groll, Ghaith Aljayyoussi, et al. "Population Pharmacokinetics of Liposomal Amphotericin B in Immunocompromised Children." Antimicrobial Agents and Chemotherapy, October 3, 2016, AAC.01427–16. http://dx.doi.org/10.1128/aac.01427-16.

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BackgroundLiposomal amphotericin B (LAmB) is widely used in the treatment of invasive fungal disease (IFD) in adults and children. There are relatively limited PK data to inform optimal dosing in children that achieves systemic drug exposures comparable to those of adults.ObjectivesTo describe the pharmacokinetics of LAmB in children aged 1-17 years with suspected or documented IFD.MethodsThirty-five children were treated with LAmB at dosages of 2.5-10 mg kg-1daily. Samples were taken at baseline and at 0.5-2.0 hourly intervals for twenty-four hours after receipt of the first dose (n=35 patien

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