Log in

Relevant bibliographies by topics / Defectos tubo neural / Dissertations / Theses

To see the other types of publications on this topic, follow the link: Defectos tubo neural.

Dissertations / Theses on the topic 'Defectos tubo neural'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 dissertations / theses for your research on the topic 'Defectos tubo neural.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Manrique, Muñoz Susana. "Anestesia y monitorización intraoperatoria en la cirugía intrauterina de los defectos del tubo neural." Doctoral thesis, Universitat Autònoma de Barcelona, 2018. http://hdl.handle.net/10803/462060.

Full text

Abstract:

La espina bífida representa el defecto congénito del tubo neural más grave compatible con la vida. Su forma más frecuente es el mielomeningocele, caracterizado por la falta de cierre del arco posterior vertebral en las semanas 3ª-4ª del desarrollo embrionario, momento en el cual la placa neural no completaría su desarrollo provocando un canal espinal abierto, con exposición al líquido amniótico de las meninges y otros elementos neurales durante el resto de la gestación. Los beneficios de la cirugía prenatal de los defectos del tubo neural y, concretamente del mielomeningocele, han sido ampli

APA, Harvard, Vancouver, ISO, and other styles

2

González, Gobartt Elena. "Study of the Secundary Neurulation in the chick embryo, a model to understand neural tube defects = Estudio de la neurulación secundaria en el embrión del pollo, un modelo para entender los defectos del tubo neural." Doctoral thesis, Universitat de Barcelona, 2019. http://hdl.handle.net/10803/668284.

Full text

Abstract:

Body axis elongation is a hallmark of the vertebrate embryo, which also comprises the morphogenesis of the caudal neural tube (NT). The contribution of bipotential neuromesodermal progenitors (NMPs) to the cranio-caudal elongation of the embryo is beginning to be understood. However, the signalling pathways and tissue remodelling events required for shaping the caudal NT from NMPs remain largely unknown, even though the failure in this process generates caudal neural tube defects (NTDs). The caudal NT in amniote embryos forms by a process termed secondary neurulation (SN). SN shapes a secondar

APA, Harvard, Vancouver, ISO, and other styles

3

Gibert, Castañer María José. "Características epidemiológicas, preventivas y metabólicas de los defectos del tubo neural en la isla de Mallorca." Doctoral thesis, Universitat Autònoma de Barcelona, 2004. http://hdl.handle.net/10803/4603.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Dueñas, Roque Milagros Mariasela. "Defectos del tubo neural en recién nacidos atendidos en el Hospital Nacional Guillermo Almenara Irigoyen – Essalud, Lima 2005-2012." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2012. https://hdl.handle.net/20.500.12672/12275.

Full text

Abstract:

Publicación a texto completo no autorizada por el autor<br>Describe cómo se presentan los defectos del tubo neural en recién nacidos atendidos en el Hospital Guillermo Almenara Irigoyen durante los años 2005 al 2012. Se realizó un estudio descriptivo retrospectivo sobre defectos del tubo neural en recién nacidos atendidos en el Hospital Guillermo Almenara Irigoyen durante los años 2005 al 2012, para lo cual se realizó la revisión de historias clínicas y se recogió los datos de interés, los mismos que fueron trasladados a una base de datos y analizadas con el programa excel para Macintosch. Se

APA, Harvard, Vancouver, ISO, and other styles

5

Burren, Katie Ann. "Metabolic analysis of neural tube defects." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1444563/.

Full text

Abstract:

Neural tube defects (NTDs), such as exencephaly and spina bifida, occur when the neural tube fails to close properly during embryonic development. Folic acid supplementation has been shown to effectively reduce the occurrence of NTDs and low folate is a known risk factor for human NTDs. However despite extensive research, the mechanism explaining how the folate status affects the incidence of NTDs remains unknown. One effect of sub-optimal folate could be suppression of the methylation cycle, which is interlinked with the folate cycle. To explore this hypothesis, a method has been developed to

APA, Harvard, Vancouver, ISO, and other styles

6

Garabedian, Berdj Hratchia. "The genetics of neural tube defects and twinning /." Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=56978.

Full text

Abstract:

Several investigators have suggested that "upper" neural tube defects (NTD's)--anencephaly, encephalocele, and thoracic spina bifida--are etiologically different from "lower" NTD's (lumbo-sacral spina bifida). This hypothesis was primarily based on the observations that the two types have different sex ratios and recurrence rates and that the NTD cases within one sibship are concordant for NTD type. In order to test this, the above figures were calculated in a sample of NTD probands from Montreal and Newfoundland. The findings were not consistent with the hypothesis. However, a previously unre

APA, Harvard, Vancouver, ISO, and other styles

7

Murdoch, Jennifer Nancy. "Genetic analysis of neural tube defects in the mouse." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325078.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Makelarski, Jennifer Ann. "Selected environmental exposures and risk of neural tube defects." Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/704.

Full text

Abstract:

With a birth prevalence of 1 in 1000, neural tube defects (NTD)s contribute considerably to morbidity and healthcare costs. Known genetic and environmental (non-inherited) risk factors for NTDs account for a small portion of risk, suggesting unidentified risk factors. In animal studies, maternal alcohol and pesticide exposures, independently, led to excess neural cell death, resulting in too few cells for neural tube closure. Human studies report no association between alcohol exposure and NTDs, but small to moderate positive associations for pesticide exposure. Such human etiologic studies of

APA, Harvard, Vancouver, ISO, and other styles

9

Paudyal, Anju. "Genetic, cellular and molecular defects in mouse mutants with severe neural tube defects." Thesis, Open University, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.530492.

Full text

Abstract:

Neural tube defects are one of the most common birth defects. This thesis includes genetic, molecular and cellular analysis of three mouse mutants with neural tube defects. chuzhoi was identified from an ENU G3 screen and exhibits craniorachischisis through failure to initiate neural tube closure. In this thesis, I show that chuzhoi carries a point mutation affecting a splice-site in the Ptk7 gene, leading to addition of three extra amino acids in the protein. Through phenotypic analysis I show that chuzhoi has a wider midline and a smaller length to width ratio, suggesting a defect in converg

APA, Harvard, Vancouver, ISO, and other styles

10

Zomignani, Andrea Peterson 1979. "Caracterização da população de recém-nascidos com diagnóstico de encefalocele." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312061.

Full text

Abstract:

Orientadores: Sergio Tadeu Matins Marba, Helder José Lessa Zambelli<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-22T03:05:39Z (GMT). No. of bitstreams: 1 Zomignani_AndreaPeterson_M.pdf: 1128762 bytes, checksum: 59ae9805910c4b220c7bfa8d2e7bcbab (MD5) Previous issue date: 2012<br>Resumo: Objetivo: Descrever uma população de recém-nascidos com encefalocele. Método: Estudo restrospectivo, descritivo e analítico por análise dos prontuários de recém-nascidos com diagnóstico de encefalocele, no Hospital da Mulher

APA, Harvard, Vancouver, ISO, and other styles

11

Pereira, Jesus Henrique Nicola. "Perfil epidemiológico e nível sérico de ácido fólico em mães de crianças portadoras de defeito do tubo neural." Universidade Federal de Sergipe, 2011. https://ri.ufs.br/handle/riufs/3744.

Full text

Abstract:

Neural tube defects (NTDs), which is a congenital malformation, in significant part on the statistics of perinatal morbidity and mortality due to their high incidence rates. The DA can be limited to the central nervous system and / or peripheral, and may also include the overlying tissues (bones, muscles and connective tissue). Folic acid (FA) is a nutrient that plays a fundamental role in the process of cell multiplication. And the remarkable importance of folic acid in preventing NTDs where published studies portray the relationship between the levels of PA and the birth of children with NTD

APA, Harvard, Vancouver, ISO, and other styles

12

Shum, Alisa Sau Wun. "The development of neural tube defects in the mouse embryo." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306186.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Palmer, A. J. "Cellular and molecular mechanisms underlying Pax3-related neural tube defects." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1469295/.

Full text

Abstract:

The neural tube is the developmental precursor of the central nervous system (CNS). Neural tube defects (NTDs) are among the commonest birth defects, affecting approximately 1 in 1000 pregnancies. They occur when the neural tube fails to close completely during neurulation, and result in an open region of the CNS. Spina bifida is an NTD affecting the spinal region, and it can lead to lifelong disability, including incontinence, motor difficulties, and paralysis below the level of the lesion. Exencephaly is an NTD affecting the cranial region, and is not compatible with life. Splotch mice carry

APA, Harvard, Vancouver, ISO, and other styles

14

Mallela, Murali Krishna. "Dysregulated Apoptosis in Teratogen-Induced Neural Tube Defects in Mice." Diss., Virginia Tech, 2011. http://hdl.handle.net/10919/37337.

Full text

Abstract:

Dysregulation of apoptosis during development is a possible mechanism for teratogen-induced birth defects. Neural tube defects (NTDs) are the second most common fetal malformations. Non-specific stimulation of maternal immune system prevents birth defects. This study investigated the role of dysregulated apoptosis in formation of NTDs from two teratogens: valproic acid (VA) and an unknown teratogen found in tap water. Interferon- Î³ (IFN Î³) was used to stimulate maternal immunity to evaluate the role of altered apoptosis in this protective mechanism. Apoptosis was evaluated using flow cytom

APA, Harvard, Vancouver, ISO, and other styles

15

Costa, Aline Teixeira da. "O aconselhamento genético como prática clínica: a anencefalia em foco." Instituto Fernandes Figueira, 2010. https://www.arca.fiocruz.br/handle/icict/8139.

Full text

Abstract:

Made available in DSpace on 2014-08-06T17:29:38Z (GMT). No. of bitstreams: 2 Aline Costa.pdf: 2324687 bytes, checksum: 04115292021785e54c4bf64f9a7bc8fd (MD5) license.txt: 1914 bytes, checksum: 7d48279ffeed55da8dfe2f8e81f3b81f (MD5) Previous issue date: 2010<br>Fundação Oswaldo Cruz. Instituto Fernandes Figueira. Departamento de Ensino. Programa de Pós-Graduação em Saúde da Criança e da Mulher. Rio de Janeiro, RJ, Brasil.<br>O objetivo desse trabalho foi discutir o aconselhamento genético (AG) como prática clínica, focalizando a anencefalia que é um defeito de fechamento de tubo neural (DFT

APA, Harvard, Vancouver, ISO, and other styles

16

Melin, Vanessa Estella. "Neural tube defects in rodents caused by a tap water contaminant." Thesis, Virginia Tech, 2011. http://hdl.handle.net/10919/76879.

Full text

Abstract:

In May of 2006, the Hrubec group suddenly began to observe neural tube defects (NTDs) in embryos of untreated control mice. Unintentional exposure to a teratogenic agent in tap water was identified as the cause. We aimed to identify the contaminant, but first we demonstrated that the NTDs were pathological being present on both gestational day 9 and 10. We also found that a second species, rats, developed NTDs when exposed to tap waters. Disinfection by-products (DBPs) arise when natural organic matter in municipal water sources reacts with disinfectants used in the water treatment process

APA, Harvard, Vancouver, ISO, and other styles

17

Fleming, Angeleen Louise. "Development and prevention of neural tube defects in the mouse embryo." Thesis, University College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287550.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Hill, Denise Suzanne. "Investigations into arsenate-induced neural tube defects in a mouse model." [College Station, Tex. : Texas A&M University, 2007. http://hdl.handle.net/1969.1/ETD-TAMU-3274.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Simpamba, Micah Mutuna. "Profiling children with neural tube defects and exploring experiences of mothers." University of the Western Cape, 2012. http://hdl.handle.net/11394/4615.

Full text

Abstract:

Magister Scientiae (Physiotherapy) - MSc(Physio)<br>Neural tube defects (NTDs) are the world‘s second most common birth defects after cardiovascular defects. In developing countries, poor access to health care services among children with NTDs contributes to early infant deaths, while those who survive live with severe disabilities. In Zambia, all children with NTDs in need of surgery are referred to Lusaka and physiotherapy services are not available in health facilities below the first level hospitals. The aim of the current study was to determine the profile of children with NTDs and to exp

APA, Harvard, Vancouver, ISO, and other styles

20

Lee, Man-yan Michelle. "The feasibility and economics of folic acid fortification in China a means to prevent neural tube defects /." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42994962.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Pena, de Castro S. C. "Proteomic and molecular analysis of neural tube defects in the mouse embryo." Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1302398/.

Full text

Abstract:

The aim of this project was to investigate the causes of spinal neural tube defects (NTDs), using the curly tail (ct/ct) mouse as a model system. The ct mutant allele corresponds to a hypomorphic allele of grainyhead-like-3 (Grhl3) gene. A two-dimensional protein gel electrophoresis (2-DE) based approach was used to compare the proteome profile of ct/ct embryos with a genetically matched wild-type strain at the stage of spinal neural tube closure. This analysis revealed a series of proteins whose abundance or 2-DE gel migration are abnormal in ct/ct embryos. Detailed follow-up analysis was per

APA, Harvard, Vancouver, ISO, and other styles

22

Cogram, Patricia. "Inositol and protein kinase C in the prevention of neural tube defects." Thesis, University College London (University of London), 2008. http://discovery.ucl.ac.uk/1445217/.

Full text

Abstract:

A number of mouse genetic mutants develop neural tube defects (NTDs). In some cases, defects can be prevented by administration of folic acid during pregnancy, whereas in other mutants there is no response. This parallels the human situation in which a proportion of NTDs appear resistant to folic acid therapy. Curly tail is the best characterised mouse model of folic acid-resistant NTDs. Previously it was shown that the incidence of spina bifida in curly tail mice can be reduced by administration of inositol during embryonic development. In this thesis, I compared the effectiveness of two isom

APA, Harvard, Vancouver, ISO, and other styles

23

Sudiwala, Sonia Jaishri. "Gene-environment interactions in the causation and prevention of neural tube defects." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10046049/.

Full text

Abstract:

The aim of the work described in this thesis is to investigate the mechanisms underlying neural tube defects (NTDs), birth defects of the developing central nervous system. The study makes use of mouse models of NTDs, and particularly focuses on the interaction between nutritional factors and genetic risk factors in determining susceptibility to NTDs. In humans some NTDs are preventable by folic acid supplementation, but this is not fully effective so investigation of alternative strategies was a key focus. The efficacy of oral nucleotide and/or inositol supplementation was evaluated for preve

APA, Harvard, Vancouver, ISO, and other styles

24

Lee, Man-yan Michelle, and 李文昕. "The feasibility and economics of folic acid fortification in China: a means to prevent neural tube defects." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42994962.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Nakatsu, Tomoko. "Neural tube closure in humans initiates at multiple sites : Evidence from human embryos and implications for the Pathogenesis of neural tube defects." Kyoto University, 2000. http://hdl.handle.net/2433/151427.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Buamah, P. K. "A study of biochemical methods for the prenatal diagnosis of neural tube defects." Thesis, University of Newcastle Upon Tyne, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370153.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Macdonald, Karen Beth. "The genetics and embryopathology of exencephaly in SELH/Bc mice." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/27983.

Full text

Abstract:

This project was the first study of the genetics and embryo-pathology of exencephaly in a partially inbred mouse stock, SELH/Bc. Exencephaly was found in 17% of SELH fetuses. Analysis of day 8-9 gestation embryos indicated that SELH embryos were collectively normal in general development, but delayed in neural tube closure relative to overall or general development compared to two normal strains of mice, ICR/Be and SWV/Bc. Exencephaly was observed to be caused by a failure of fusion of the cranial neural folds in the mesencephalon region in SELH. All SELH embryos appeared to be abnormal in th

APA, Harvard, Vancouver, ISO, and other styles

28

Devine, Scott T. West Suzanne L. "The identification and validation of neural tube defects in the General Practice Research Database." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,1221.

Full text

Abstract:

Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2007.<br>Title from electronic title page (viewed Mar. 26, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the School of Public Health (Epidemiology)." Discipline: Epidemiology; Department/School: Public Health.

APA, Harvard, Vancouver, ISO, and other styles

29

Awwad, Fuad A. A. "External imprecise covariates in an epidemiological study of environmental lead and neural tube defects." Thesis, Lancaster University, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286981.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Neasham, David Edward. "The geographical epidemiology of neural tube defects and down syndrome in England and Wales." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.405964.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Chen, Wei-Hwa. "Roles of retonic acid and its nuclear receptors in mouse spinal neural tube defects." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359376.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Buccimazza, Sandro Sabatino. "The prevalence of neural tube defects and the outcome of myelomeningocele in Cape Town." Master's thesis, University of Cape Town, 1996. http://hdl.handle.net/11427/25629.

Full text

Abstract:

This study was designed to document the prevalence of neural tube defects in Cape Town and to determine the outcome of children born with a myelomeningocele and operated on within the Neurosurgical service of the University of Cape Town. The aim of the prevalence study was to document the frequency of neural tube defects (NTD) over a twenty year period in Cape Town (1973 - 1992) and to determine the effects of race, gender, maternal age, parity, and season of conception on the prevalence. Multiple sources of ascertainment were used, including all maternity hospital records, neurosurgical and s

APA, Harvard, Vancouver, ISO, and other styles

33

Mancino, Franca. "Genetic linkage studies of the splotch neural tube defect gene on mouse chromosome 1." Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=56943.

Full text

Abstract:

Genetic linkage studies of the spontaneously arising splotch allele, Sp, were conducted to identify closely linked molecular markers as a preliminary step for the isolation of the mutant gene. Restriction fragment length polymorphism and microsatellite size variation analyses were employed to follow the segregation of Sp in relation to eight or ten loci previously assigned to the proximal portion of mouse chromosome 1. Although results from an interspecific ((Sp/+ x Mus spretus)F1-Sp x C57BL/6J) backcross study were inconclusive, a panel of 125 intraspecific ((Sp/+ x CBA/J)F1-Sp x CBA/J) backc

APA, Harvard, Vancouver, ISO, and other styles

34

Conceição, Ricardo Campelo da. "Conhecimento de médicos e enfermeiros obstetras sobre a prevenção dos defeitos de fechamento do tubo neural." Universidade Federal de Juiz de Fora (UFJF), 2009. https://repositorio.ufjf.br/jspui/handle/ufjf/3904.

Full text

Abstract:

Submitted by Renata Lopes (renatasil82@gmail.com) on 2017-03-29T18:19:17Z No. of bitstreams: 1 ricardocampelodaconceicao.pdf: 3005415 bytes, checksum: 93485f733d9f5ab38c981b4eca76fc2b (MD5)<br>Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2017-03-30T11:24:14Z (GMT) No. of bitstreams: 1 ricardocampelodaconceicao.pdf: 3005415 bytes, checksum: 93485f733d9f5ab38c981b4eca76fc2b (MD5)<br>Made available in DSpace on 2017-03-30T11:24:14Z (GMT). No. of bitstreams: 1 ricardocampelodaconceicao.pdf: 3005415 bytes, checksum: 93485f733d9f5ab38c981b4eca76fc2b (MD5)

APA, Harvard, Vancouver, ISO, and other styles

35

Santos, Mara Lúcia Pacheco Lemos dos. "Impacto do enriquecimento de alimentos com ácido fólico na ocorrência de defeitos do tubo neural." Universidade Federal de Uberlândia, 2015. https://repositorio.ufu.br/handle/123456789/12837.

Full text

Abstract:

Introduction: Neural Tube Defects (NTD) is a congenital malformation, witch results from the incomplete closure of the neural tube during the fourth week of embryonic development. It is a complex malformation, the second more frequent in the United States of America. It can be prevented by using folic acid (FA) from pre-conception period until the early months of pregnancy. Mandatory flours enrichment with FA occurs in Brazil since 2002. The aim of this study was to evaluate the impact of this action on NTD occurrence, especially on the meningomyelocele sub type, at the Clinical Hospital of th

APA, Harvard, Vancouver, ISO, and other styles

36

Stamm, Demetra Serena North Kari E. "Genetic investigation of both complex and Mendelian disorders neural tube defects and Native American myopathy /." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,1401.

Full text

Abstract:

Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2007.<br>Title from electronic title page (viewed Apr. 25, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Curriculum of Genetics." Discipline: Genetics and Molecular Biology; Department/School: Medicine.

APA, Harvard, Vancouver, ISO, and other styles

37

Gardner, Patricia Emma. "Antibodies to secretory acetylcholinesterase : their possible role in the prenatal diagnosis of neural tube defects." Thesis, University of Bath, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277120.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Ross, Micah Marie. "A Comprehensive Comparison of Teratogenic Compounds Known to Induce Neural Tube Defects in the Chicken Embryo." BYU ScholarsArchive, 2020. https://scholarsarchive.byu.edu/etd/9257.

Full text

Abstract:

One of the first embryonic structures generated during early human development is the neural tube. The embryonic process of neurulation, including neural tube closure, is necessary for proper brain and spinal cord development, whereas improper closure leads to neural tube defects including anencephaly, spina bifida, and craniorachischisis. The mechanism by which these defects occur is unknown, but some evidence suggest that redox disruption may play a role. Cellular redox state is important in regulating key processes during neural tube closure, including differentiation, proliferation, gene e

APA, Harvard, Vancouver, ISO, and other styles

39

Neuhouser, Marian L. Stone. "Absorption of pteroylglutamic acid and pteroylpolyglutamic acid in women with a history of neural tube defect affected pregnancies vs. controls /." Thesis, Connect to this title online; UW restricted, 1996. http://hdl.handle.net/1773/6613.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Stahlhut, Lynn M. "Folic acid : consumption and knowledge for the prevention of neural tube defects among college-aged women /." View online, 2004. http://repository.eiu.edu/theses/docs/32211131180526.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Mezzomo, Cíntia Leal Sclowitz. "PREVENÇÃO DE DEFEITOS DO TUBO NEURAL: PREVALÊNCIA DO USO DA SUPLEMENTAÇÃO DE ÁCIDO FÓLICO E FATORES ASSOCIADOS EM GESTANTES NA CIDADE DE PELOTAS RS, BRASIL." Universidade Catolica de Pelotas, 2006. http://tede.ucpel.edu.br:8080/jspui/handle/tede/397.

Full text

Abstract:

Made available in DSpace on 2016-03-22T17:27:38Z (GMT). No. of bitstreams: 1 cintia.pdf: 399237 bytes, checksum: 411794e4a2f292dd1123c42f8b410d51 (MD5) Previous issue date: 2006-11-20<br>To determine folic acid use and associated factors, a cross-sectional population-based study was carried out in the five maternities from Pelotas - RS, Brazil. Data were collected from April 1st to August 15th, 2006. 1450 women were interviewed. A standard questionnaire was applied in the hospitals. Statistical analysis was done by Poisson Regression. Prevalence of folic acid consumption during pregnancy was

APA, Harvard, Vancouver, ISO, and other styles

42

Nakouzi, Ghunwa Akram. "Genetic and Phenotypic Response of Neural Tube Defect Mouse Mutants to Folic Acid." Case Western Reserve University School of Graduate Studies / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=case1246538783.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Seo, Jung Hwa. "Mutations in the Planar Cell Polarity gene, Fuzzy, are associated with neural tube defects in humans." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=106542.

Full text

Abstract:

The planar cell polarity (PCP) pathway is evolutionally conserved from flies to vertebrate; it controls multiple cellular processes during embryonic development. One of such processes is neurulation, which gives rise to the brain and spinal cord. Mutations in the PCP genes in mice cause a very severe neural tube defect (NTD), called craniorachischisis, establishing that the PCP pathway is an important regulator of neural tube closure. NTDs are the second most common congenital malformation in humans. Since the etiology of NTDs in humans is complex and involves both genetic and environmental fa

APA, Harvard, Vancouver, ISO, and other styles

44

Warren-Mears, Victoria Ann. "Folic acid and the prevention of neural tube defects : western Washington women's knowledge, beliefs and opinions /." Thesis, Connect to this title online; UW restricted, 2001. http://hdl.handle.net/1773/6591.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Tan, Jenny Chiew Yeong. "Interrelationships of zinc, copper, vitamin A and various proteins in pregnancies complicated by neural-tube defects." Thesis, Imperial College London, 1987. http://hdl.handle.net/10044/1/46716.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Santiago-Colón, Albeliz. "Association between Maternal Occupational Exposure to Polycyclic Aromatic Hydrocarbons and Risk of Selected Birth Defects in the National Birth Defects Prevention Study." University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1540564606643075.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Rodrigues, Adriana Teixeira. "Obesidade e o nascimento de bebês com fendas lábio-palatinas." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/6/6136/tde-03112006-081338/.

Full text

Abstract:

Introdução - A incidência das fendas lábio palatinas, é de 1 para cada 700 nascidos vivos na população mundial, trata-se de uma má-formação congênita que pode ocorrer devido a fatores endógenos ou exógenos. Objetivo Relacionar o índice de massa corporal (IMC) materno com o nascimento de bebês com fendas. Métodos Trata-se de um estudo tipo caso-controle. Foram incluídas 800 mães com idade entre 18 e 35 anos, que não apresentaram suspeita ou confirmação de diabete mellitus ou gravídica e bebês com peso entre 2.500 e 4.500 gramas nascidos entre a 37ª e a 42ª semana de gestação que não apres

APA, Harvard, Vancouver, ISO, and other styles

48

Mathews, Stevie. "DIAGNOSING ANENCEPHALY IN ARCHAEOLOGY: A COMPARATIVE ANALYSIS OF NINE CLINICAL SPECIMENS FROM THE SMITHSONIAN INSTITUTION NATION." Master's thesis, University of Central Florida, 2008. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/2888.

Full text

Abstract:

The inclusion of human fetal skeletons in the archaeological record can reveal much about past cultures' perception of life and death. The preservation of fetal remains in the archaeological record is a rarity, and the discovery of pathological skeletons is even rarer. A fetal skeleton from a Roman period cemetery (c. 31BC - 303AD) in the Dakhleh Oasis, Egypt, displays what are thought to be classic skeletal indicators of the neural tube defect, anencephaly. The published literature concerning the skeletal diagnosis of anencephaly is scant so in order to diagnose this individual it is pertinen

APA, Harvard, Vancouver, ISO, and other styles

49

Bonham, James Robert. "A study of molecular forms of the cholinesterases with particular reference to Hirschsprung's disease and neural tube defects." Thesis, University of Newcastle Upon Tyne, 1986. http://hdl.handle.net/10443/545.

Full text

Abstract:

Acetylcholinesterase [ACNE) and butyrylcholinesterase [EChE) were studied in amniotic fluid in relation to the detection of neural tube defects CNTD), and in rectal tissue in the diagnosis of Hirschsprung's disease. An automated assay is described for measurement of AChE and BChE activity in amniotic Fluid, and an increase in both is found in the presence of NTD. Analysis of AChE molecular forms by sucrose density sedimentation revealed three species with differing sedimentation coefficients and molecular masses: monomeric G1[4. OS, 78KOa), dimeric G2[5.5S, 126KOa) and tetrameric G4(10.35,256K

APA, Harvard, Vancouver, ISO, and other styles

50

Harvey, Michael Hugh. "An investigation of potato alkaloid levels in the normal population and their relationship to foetal neural tube defects." Thesis, University of Surrey, 1988. http://epubs.surrey.ac.uk/847500/.

Full text

Abstract:

Radioimmunoassay methods were developed for the measurement of solanidine and total alkaloid in serum, urine and saliva. Solanidine and total alkaloid concentrations were measured in a group of normal pregnant women and a group of women pregnant with a foetus subsequently shown to be affected by a neural tube defect (NTD). Serum alkaloid concentrations were, contrary to expectations, lower in the NTD group, casting doubt on the theory suggesting a link between potato alkaloids and NTD serum zinc and folate concentrations were also measured in the two groups and no significant differences were

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!