Academic literature on the topic 'Defined Daily Dose (DDD)'

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Journal articles on the topic "Defined Daily Dose (DDD)"

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Montecatine-Alonso, Elena, Marta Mejías-Trueba, Walter Alfredo Goycochea-Valdivia, et al. "Development of Antimicrobial Defined Daily Dose (DDD) for the Pediatric Population." Antibiotics 12, no. 2 (2023): 276. http://dx.doi.org/10.3390/antibiotics12020276.

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Antimicrobial stewardship programs (ASPs) optimize antimicrobial use, improve patient outcomes, and reduce resistance. To assess the effectiveness of ASPs, it is necessary to have indicators that can be widely used. Defined daily dose (DDD) was designed by WHO for the adult population as a consumption indicator. However, there are no DDDs adapted to the pediatric population. The main objective of this study is to establish the most appropriate DDD values in this population. An observational, retrospective, multicenter study was conducted. Antimicrobial prescriptions were collected from pediatr
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Oktavia, Maria, Suharjono, and Windi Virdiyanti. "Analisis Penggunaan Antibiotik pada Pasien Rawat Inap Dengan Metode Defined Daily Dose." MPI (Media Pharmaceutica Indonesiana) 5, no. 2 (2023): 165–71. http://dx.doi.org/10.24123/mpi.v5i2.5862.

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 Antibiotik adalah obat yang digunakan untuk mencegah dan mengobati infeksi bakteri. Penggunaan antibiotik yang kurang tepat dapat memicu resistensi antibiotik yang merupakan masalah terbesar bagi kesehatan manusia. Resistensi antibiotik dapat meningkatkan length of stay (LOS), meningkatkan biaya pengobatan, dan meningkatkan angka mortalitas. Salah satu cara untuk menanggulangi resistensi antibiotik adalah dengan penggunaan antibiotik secara bijak. Metode Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) digunakan untuk menilai kuantitas penggunaan antibio
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Wahyudi, Adiyat Edy, Jaka Fadraersada, and Muhammad Amir Masruhim. "Evaluasi Penggunaan Antibiotika Berdasarkan Metode Defined Daily Dose (DDD) pada Pasien Ulkus Diabetikum." Proceeding of Mulawarman Pharmaceuticals Conferences 8 (December 31, 2018): 21–29. http://dx.doi.org/10.25026/mpc.v8i1.298.

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Dampak penggunaan antibiotika yang tidak rasional pada pasien Ulkus kaki diabetik yaitu meningkatnya kejadian resistensi, kejadian efek samping obat, terjadi kegagalan terapi, penyakit yang dialami pasien bertambah parah sehingga menurunkan kualitas pelayanan kesehatan. Tujuan penelitian ini adalah untuk menghitung nilai DDD untuk mengetahui tingkat rasional penggunaan antibiotika pada pasien ulkus diabetikum yang menerima terapi antibiotika. Penelitian ini menggunakan rancangan observasional retrospektif dan perolehan data secara deskriptif kuantitatif mengunakan perhitungan DDD. Penilaian se
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Villanueva-Bueno, Cristina, Elena Montecatine-Alonso, Francisco Jiménez-Parrilla, et al. "Antimicrobial Defined Daily Dose in Neonatal Population: Validation in the Clinical Practice." Antibiotics 12, no. 3 (2023): 602. http://dx.doi.org/10.3390/antibiotics12030602.

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Background: Currently, there is no validated method for estimating antimicrobial consumption in the neonatal population, as it exists for adults using Defined Daily Doses (DDD). In neonatology, although there are different methods, each one with advantages and disadvantages, there is no unified criterion for use. The aim of this study is to validate the neonatal DDD designed as a new standardised form of antimicrobial consumption over this population. Methods: The validation of the neonatal DDD, Phase II of the research project, was carried out through a descriptive observational study. Period
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Lestari, Putri Dwi, Esti Dyah Utami, and Masita Wulandari Suryoputri. "Evaluasi Penggunaan Antibiotik di Bangsal Penyakit Dalam RSUD Prof. Dr. Margono Soekarjo Purwokerto." Acta Pharmaciae Indonesia 6, no. 1 (2019): 20–28. https://doi.org/10.5281/zenodo.3707171.

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Tingginya prevalensi penyakit infeksi di Indonesia menyebabkan penggunaan antibiotik meningkat. Penggunaan antibiotik yang tidak tepat dapat memicu terjadinya resistensi yang dapat meningkatkan morbiditas, mortalitas, dan biaya kesehatan. Peneliti melakukan evaluasi penggunaan antibiotik di Bangsal Penyakit Dalam RSUD Prof. Dr. Margono Soekarjo Purwokerto yang bertujuan untuk mengetahui jumlah penggunaan antibiotik dan mengevaluasi kualitas penggunaan antibiotik di rumah sakit tersebut. Penelitian ini merupakan penelitian observasional deskriptif evaluatif dengan pendekatan kualitatif dan kuan
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Hidayati, Ana, Susan Candradewi, and Syahnindita Erhan. "DEFINE DAILY DOSE (DDD) PENGGUNAAN ANTIBIOTIKA PADA PROFILAKSIS PEMBEDAHAN DI RSUD CILACAP." Medical Sains : Jurnal Ilmiah Kefarmasian 7, no. 3 (2022): 635–44. http://dx.doi.org/10.37874/ms.v7i3.305.

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Proses pembedahan adalah proses pembukaan bagian tubuh yang akan ditangani dan diakhiri dengan penutupan dan penjahitan luka. Kondisi ini memungkinkan terjadinya infeksi yang dapat dicegah dengan pemberian antibiotik. Penelitian ini bertujuan untuk mengetahui nilai DDD penggunaan antibiotik pada pasien rawat inap bedah umum di Rumah Sakit Umum Daerah (RSUD) Cilacap. Evaluasi penggunaan obat dengan DDD bertujuan untuk melihat gambaran dosis pemeliharaan rata-rata per hari suatu obat yang digunakan sebagai indikasi utama pada orang dewasa. Penelitian ini merupakan penelitian deskriptif yang akan
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Pua Upa, Nurul Fatmawati, Widyati Widiaty, and Frans O. H. Prasetyadi. "Profil Penggunaan Antibiotik Pada Pasien Pediatri Rujukan Berdasarkan Sistem Defined Daily Dose (DDD)." MPI (Media Pharmaceutica Indonesiana) 3, no. 1 (2020): 44–51. http://dx.doi.org/10.24123/mpi.v3i1.2503.

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Tujuan dari penelitian ini adalah untuk mengetahui profil penggunaan antibiotik pada pasien pediatri yang dirujuk ke RSPAL Dr. Ramelan selama bulan April hingga Juli 2019. Penelitian ini merupakan penelitian observasional deskriptif yang dilakukan secara prospektif. Variabel yang terlibat adalah besar penggunaan antibiotik yang dinyatakan dalam satuan Defined Daily Dose (DDD)/100 hari rawat inap dan standar yang digunakan berdasarkan ketentuan dari WHO. Terdapat 30 subyek yang dirujuk ke RSPAL Dr. Ramelan. Sebagian besar subyek telah tinggal lebih dari 48 jam di rumah sakit sebelumnya, mereka
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Christensen, T., and R. Møller Jeppesen. "QTc interval in patients diagnosed with schizophrenia receiving different defined daily dose (DDD) of antipsychotics." European Psychiatry 41, S1 (2017): s805. http://dx.doi.org/10.1016/j.eurpsy.2017.01.1558.

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IntroductionBoth 1st and 2nd generation of antipsychotics are associated with prolonged QTc interval. Prolonged QTc can lead to ventricular tachycardia and Torsade's de pointes, ultimatime resulting to cardiac arrest and sudden death. Prolonged QTc interval due to increased DDD has not yet been investigated.ObjectiveTo investigate whether increased DDD of antipsychotics, causes further prolonged QTc, by patients diagnosed with schizophrenia.AimsTo learn more about antipsychotics impact on the QTc interval in patients diagnosed with schizophrenia.MethodsAn observational study of unselected pati
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Vojnović, M., Dž Jakovljević, V. Jakovljević, and V. Pilija. "EVALUATION OF USAGE ANTIINFECTIVE MEDICAMENTS FOR SYSTEMATIC APLICATION ON THE BASIS OF DEFINED DAILY DOSE." Praxis medica 32, no. 1 (2004): 49–52. http://dx.doi.org/10.70949/pramed200401067v.

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<p>Defined daily dose (DDD) is arbitrary chosen technical unit for measuring medicament usage and it is not a recommended therapeutic dose. It is in fact a statistical parameter for monitoring medicaments usage, and it is related to the dose which is usually prescribed for the indication that the medicament was registered for. The aim of this work is to perform a detailed analysis of the extent and structure of the region of South Backa. Antiinfective medicaments in systematic use, according to the obtained data, participate with only 7.96 DDD/1000 inhabitants. The most applied p
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Hakimudin, Tria Rahmah, Evi Sovia, and Dannurendra Dannurendra. "EVALUASI PENGGUNAAN ANTIBIOTIK PADA PASIEN RAWAT INAP BANGSAL BEDAH DENGAN METODE DEFINED DAILY DOSE (DDD)." Medika Kartika Jurnal Kedokteran dan Kesehatan, Volume 8 No 1 (March 30, 2025): 48–57. https://doi.org/10.35990/mk.v8n1.p48-57.

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Pembedahan merupakan prosedur terapeutik yang bersifat invasif sehingga akan menyebabkan terbentuknya luka terbuka di area yang dibedah. Kondisi ini membuat pasien yang menjalani pembedahan sangat rentan terhadap infeksi mikroba. Sebagai upaya pencegahan infeksi mikroba adalah dengan pemberian antibiotik. Evaluasi dengan menggunakan DDD (Defined Daily Dose) bertujuan untuk memberikan gambaran tentang dosis pemeliharaan rata-rata per hari untuk obat yang digunakan dengan indikasi utama pada pasien dewasa. Penelitian ini bertujuan untuk mengetahui nilai DDD penggunaan antibiotik pada pasien rawa
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Dissertations / Theses on the topic "Defined Daily Dose (DDD)"

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Nghishekwa, Bona Naita Tukondjeni. "Trends in antibiotic consumption in the Namibian Public Health Sector 2010-2016." University of the Western Cape, 2018. http://hdl.handle.net/11394/6870.

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Magister Public Health - MPH<br>Background Antibiotic resistance is a phenomenon that occurs naturally and is accelerated by use. There have been no studies looking at trends in antibiotic consumption in the public health sector in Namibia, which provides services to 85% of the population. Aim This study described the pattern of antibiotic consumption in the Namibian public health sector based on distribution of antibiotics from Central Medical Stores (CMS) to the 13 regions in the country. Methodology Antibiotic consumption data from distribution records at the Central Medical Store (CMS),
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Bopape, Susan Mothekoa. "The management of dyslipidemia in a private health care setting : a managed pharmaceutical care approach / Susan Mothekoa Bopape." Thesis, North-West University, 2004. http://hdl.handle.net/10394/483.

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The global anti-dyslipidemic market grew by 19% from 2000 to 2001, achieving sales of over $21 billion (Smith, 2004: 2). This market is currently well sewed by a number of effective and well-tolerated treatments. Lipid-lowering drugs are considered as the first choice drugs in control of dyslipidemias and they are well tolerated by most patients. As with many drug therapies, there should be a balance between the benefits of cholesterol lowering agents, increased medication cost and the overall risk of adverse drug reactions. According to Ballesteros (2001: 514), hypolipidemic drugs are consume
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Le, Roux Jan Daniël. "Prescribing patterns of antidepressants with known off-label indications among adults / Jan Daniël le Roux." Thesis, 2014. http://hdl.handle.net/10394/10753.

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“Off-label use” is defined as the use of medicine for indications other than recommended or registered for, e.g. the prescribing of a particular active substance for a patient younger than the substance is recommended or indicated for, or different formulations or dosages of a substance (Ekins-Daukes et al., 2004:349; Stedman’s medical dictionary, 2006). Off-label prescribing is common, and fluctuates by physician, patient and drug (Eguale et al., 2012:781). Drug classes most commonly prescribed off-label include anti-asthmatic, cardiovascular drugs and antidepressants. Lee et al. (2012:140) f
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Hu, Ya-Tzu, and 胡雅姿. "Corrections between Anti-InfectiveUtilization as Measured by Defined Daily Dose and Quality Indicators in a Hospital." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/26709647804658885174.

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碩士<br>高雄醫學大學<br>藥學研究所碩士在職專班<br>97<br>Study Objective: To investigate relations between the use of anti-infectives and quality indicators of hospitalization, including nosocomial infection density, average length of stay, net and gross mortality rate in a regional teaching hospital in Taiwan during the period 2004 to 2008. Design: Retrospective cross-sectional study. Setting: A 320-bed regional teaching hospital in Taiwan. Methods: The DDD of use of anti-infectives was analyzed in wards in a regional teaching hospital during the period 2004 to 2008. The DDD was based on that defined by the WHO
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Books on the topic "Defined Daily Dose (DDD)"

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Wickens, Hayley. Measuring antibiotic consumption and outcomes. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198758792.003.0006.

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Understanding how antimicrobial usage is monitored and reported is crucial when reading the literature on antimicrobial stewardship and assessing outcomes of local programmes. This chapter covers the methods used to monitor antimicrobial usage and the associated terminology, such as defined daily dose (DDD), average daily quantities (ADQs), and days of therapy (DOT), and gives and overview of usage monitoring in primary and secondary healthcare in the UK and beyond. This chapter also covers potential roles for electronic prescribing and information management systems in the monitoring of antim
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Lysack, Krista. Chronometres. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198836162.001.0001.

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What does it mean to feel time, to sense its passing along the sinews and nerves of the body as much as the synapses of the mind? And how do books, as material arrangements of print and paper, mediate such temporal experiences? Chronometres: Devotional Literature, Duration, and Victorian Reading is a study of the time-inflected reading practices of religious literature, the single largest market for print in Victorian Britain. It examines poetic cycles by John Keble, Alfred Tennyson, Christina Rossetti, and Frances Ridley Havergal; family prayer manuals, Sunday-reading books and periodicals; a
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Book chapters on the topic "Defined Daily Dose (DDD)"

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Nahler, Gerhard. "defined daily dose (DDD)." In Dictionary of Pharmaceutical Medicine. Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-89836-9_368.

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Liang, Guowei, Yinsheng Zhang, Haomin Li, Weihong Chen, and Huilong Duan. "A Surveillance Platform of Antimicrobial Use in Hospital Based on Defined Daily Dose." In Ubiquitous Computing Application and Wireless Sensor. Springer Netherlands, 2015. http://dx.doi.org/10.1007/978-94-017-9618-7_61.

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"Defined daily doses for statistical purposes (S-DDD) for psychotropic substances." In Psychotropic Substances 2011. United Nations, 2012. http://dx.doi.org/10.18356/9789210552370c004.

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"Defined daily doses for statistical purposes (S-DDD) for psychotropic substances." In Psychotropic Substances 2016. UN, 2017. http://dx.doi.org/10.18356/be97fb91-en-fr-es.

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"Table III. Defined daily doses for statistical purposes (S-DDD) for psychotropic substances." In Psychotropic Substances 2012. UN, 2013. http://dx.doi.org/10.18356/4a50f7fd-en-fr-es.

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"Table 3. Defined daily doses for statistical purposes (S-DDD) for psychotropic substances." In Psychotropic Substances 2015. UN, 2016. http://dx.doi.org/10.18356/544b08f9-en-fr-es.

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"Table 3. Defined daily doses for statistical purposes (S-DDD) for psychotropic substances." In Psychotropic Substances 2014. UN, 2016. http://dx.doi.org/10.18356/57282851-en-fr-es.

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"Table III. Defined daily doses for statistical purposes (S-DDD) for psychotropic substances." In Psychotropic Substances. UN, 2015. http://dx.doi.org/10.18356/5d9d42f3-en-fr-es.

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Eryilmaz Esat N. "An Approach to &lsquo;Dynamic &ndash; DDD (Defined Daily Dose) Monitoring&rsquo; to Reduce Adverse Clinical Outcomes and Increase Patient Safety: Information Repositories and Event Triggers in Clinical Practice." In Studies in Health Technology and Informatics. IOS Press, 2011. https://doi.org/10.3233/978-1-60750-740-6-156.

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The goal of every effort and actions/interventions in almost all healthcare settings throughout the world's health systems -primary care, inpatient, outpatient encounters, diagnostic and therapeutic interventions, peri-operative settings- is and has been to achieve a well defined outcome (a kind of improvement in health status of the patient under consideration, an observable and significant change(s) in selected set(s) of clinical parameters confirmed by laboratory results and pathology findings, improvements in clinical outcomes). Clinical inefficiencies, in this context, should be addressed
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"Levels of consumption of groups of psychotropic substances in defined daily doses for statistical purposes (S-DDD) per thousand inhabitants per day." In Psychotropic Substances. UN, 2018. http://dx.doi.org/10.18356/4faa6aa5-en-fr-es.

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Conference papers on the topic "Defined Daily Dose (DDD)"

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Cruz, Fernando Costa da, BRENO FIGUEIREDO MAIA, FERNANDO AUGUSTO MIRANDA COSTA, NAILLA BYATRIZ SILVA DE MORAIS, and MAYKON LEAL BRANDÃO. "A INFLUÊNCIA DE ANTIBIÓTICOS NA RESISTÊNCIA E BACTÉRIAS E NO AUMENTO DOS RISCOS À SAÚDE HUMANA: UMA REVISÃO DE LITERATURA." In II Congresso Nacional de Microbiologia Clínica On-line. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/ii-conamic/36.

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Introdução: Os antibióticos são fundamentais para o tratamento das infecções bacterianas. Entretanto, anos de irrestrita utilização e de uso inadequado desses fármacos têm criado ambientes nos quais as bactérias resistentes a antibióticos acabam se multiplicando. Tomando como base a ideia de que bactérias de microbiota são as que carregam grande quantidade de genes de resistência a uma ou mais drogas, é possível predizer que os mecanismos de resistência podem ser intrínsecos ao microrganismo estudado ou adquiridos por meio de transmissão de material genético. Objetivo: Identificar e revisar, d
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Strobino, S., M. Lecis, E. Viglione, and G. Ceravolo. "1ISG-003 Biosimilar growth hormone: defined daily dose in an italian district after the regional tender." In 24th EAHP Congress, 27th–29th March 2019, Barcelona, Spain. British Medical Journal Publishing Group, 2019. http://dx.doi.org/10.1136/ejhpharm-2019-eahpconf.3.

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Montecatine-Alonso, E., M. Mejias-Trueba, MV Gil-Navarro, et al. "NP-007 Validation of antimicrobial defined daily dose for the paediatric population: Final results of KiDDDs project." In 28th EAHP Congress, Bordeaux, France, 20-21-22 March 2024. British Medical Journal Publishing Group, 2024. http://dx.doi.org/10.1136/ejhpharm-2024-eahp.7.

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Suárez Casillas, P., M. Mejías-Trueba, AB Guisado-Gil, et al. "6ER-006 Analysis of the antimicrobial use in neonatal population based on a defined daily dose method." In 29th EAHP Congress, Copenhagen, Denmark, 12-13-14 March 2025, Person centred pharmacy — Navigating digital health. British Medical Journal Publishing Group, 2025. https://doi.org/10.1136/ejhpharm-2025-eahp.453.

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"TESTING MEASURING DEVICES IN WELL-DEFINED PULSED RADIATION FIELDS." In RAD Conference. RAD Centre, Niš, Serbia, 2023. http://dx.doi.org/10.21175/radproc.2023.08.

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There is a growing need for research, detector testing and metrological methods to study pulsed radiation fields because many facilities (e.g. high-power laser facilities) and devices produce pulsed ionizing radiation. Although the ELI ALPS laser facility is already operational in Hungary, the operational parameters (frequency of the laser shots, daily operational time of the laser, energy of the laser pulse and the number of the generated particles in the laser-matter interaction) are low, thus the generated pulsed radiation is negligible. Over the following ten years, the operational paramet
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Kakkar, V. V. "A DOSE RANGING STUDY DESIGNED TO ASSESS THE SAFETY AND EFFICACY OF A LOW MOLECULAR WEIGHT HEPARIN FRAGMENT (FRAGMIN) AS PROPHYLAXIS AGAINST DEEP VEIN THROMBOSIS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643222.

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A preliminary study has reported that a single daily injection of 2500 and 5000 U of Fragmin was equally effective in preventing deep vein thrombosis1 (DVT). All the patients who developed DVT (4.9%) had undergone surgery for malignant disease. However, small numbers of patients were investigated and therefore detailed subject analysis was not possible. In the present study, 1000 patients scheduled to undergo elective major abdominal, urological or gynaecological surgery were investigated. They received one of three regimens; 5000 (Group I), 2500 (Group II) or 1500 (Group III) U of Fragmin dai
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Silvério, Gabriel André, Renata Cristine Alves, Pedro Arthur Possan, et al. "Acute pregabalin cerebellar ataxia." In XIV Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s1.515.

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Female patient, 65-year-old, complaining of imbalance and difficulty walking for 15 days, associated with dizziness and diplopia, with worsening symptoms in the last four days. In recent use of pregabalin 75 mg daily to treat chronic pain, with dose increase in the last four days. On examination, he presented ataxic gait, drunken speech, pendular reflex, dysmetria and dysdiadochokinesia. We opted for the suspension of Pregabalin and complementary investigation for cerebellar ataxia with imaging examination, examination of the cerebrospinal fluid (CSF) and laboratory tests. Magnetic resonance i
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Jackson, Kristina, and Nayomi Plaza. "Challenges in proposing omega-3 fatty acid recommendations for the public." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/fgey5940.

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Long-chain omega-3 fatty acids, eicosapentaenoic and docosahexaenoic acids (EPA, DHA), are important nutrients, but they do not have a Dietary Reference Intake (DRI) recommendation. This lack of recognition as essential nutrients makes it difficult to set population guidelines for EPA and DHA (like the Dietary Guidelines for Americans). Challenges in proposing EPA and DHA recommendations for the public are mainly determining which health outcomes reflect a €œdeficiency€ for EPA and DHA and defining the EPA and DHA dose recommendation for the general public and at each life stage. The moderniz
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