Log in

Relevant bibliographies by topics / Delayed strain / Journal articles

To see the other types of publications on this topic, follow the link: Delayed strain.

Journal articles on the topic 'Delayed strain'

Author: Grafiati

Published: 25 May 2024

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Delayed strain.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Mizumoto, Hiroyuki, Yuji Tomaru, Yoshitake Takao, Yoko Shirai, and Keizo Nagasaki. "Diverse Responses of the Bivalve-Killing Dinoflagellate Heterocapsa circularisquama to Infection by a Single-Stranded RNA Virus." Applied and Environmental Microbiology 74, no. 10 (2008): 3105–11. http://dx.doi.org/10.1128/aem.02190-07.

Full text

Abstract:

ABSTRACT Viruses are believed to be significant pathogens for phytoplankton. Usually, they infect a single algal species, and often their infection is highly strain specific. However, the detailed molecular background of the strain specificity and its ecological significance have not been sufficiently understood. Here, we investigated the temporal changes in viral RNA accumulation and virus-induced cell lysis using a bloom-forming dinoflagellate Heterocapsa circularisquama and its single-stranded RNA virus, HcRNAV. We observed at least three host response patterns to virus inoculation: sensiti

APA, Harvard, Vancouver, ISO, and other styles

2

Wang, Shifeng, Yuhua Li, Giorgio Scarpellini, et al. "Salmonella Vaccine Vectors Displaying Delayed Antigen Synthesis InVivo To Enhance Immunogenicity." Infection and Immunity 78, no. 9 (2010): 3969–80. http://dx.doi.org/10.1128/iai.00444-10.

Full text

Abstract:

ABSTRACTWe have developed a regulated delayed antigen synthesis (RDAS) system for use in recombinant attenuatedSalmonellavaccine (RASV) strains to enhance immune responses by reducing the adverse effects of high-level antigen synthesis. This system includes a chromosomal repressor gene,lacI, expressed from the arabinose-regulatedaraCPBADpromoter. LacI serves to regulate expression from a plasmid promoter, Ptrc, that directs antigen synthesis. In the presence of arabinose LacI is produced, which binds to Ptrc, blocking antigen synthesis.In vivo, an arabinose-poor environment, the concentration

APA, Harvard, Vancouver, ISO, and other styles

3

Parra, Araceli, Carmen Ponte, Carlos Cenjor, Carmen Martínez-Marín, and Francisco Soriano. "Effect of Antibiotic Treatment Delay on Therapeutic Outcome of Experimental Acute Otitis Media Caused by Streptococcus pneumoniae Strains with Different Susceptibilities to Amoxicillin." Antimicrobial Agents and Chemotherapy 48, no. 3 (2004): 860–66. http://dx.doi.org/10.1128/aac.48.3.860-866.2004.

Full text

Abstract:

ABSTRACT The effect of delayed administration of amoxicillin on the course of acute otitis media (AOM) caused by two Streptococcus pneumoniae strains with different susceptibilities to amoxicillin (MICs of 0.016 and 1 μg/ml for strains A and B, respectively) was evaluated in the gerbil model. The organisms were inoculated by transbullar challenge into the middle ear, and antibiotic treatment was administered at various times thereafter. The bacteriological and clinical efficacies of treatment diminished significantly with the delay of antibiotic administration. The bacterial eradication rates

APA, Harvard, Vancouver, ISO, and other styles

4

Shi, Huoying, Shifeng Wang, and Roy Curtiss. "Evaluation of Regulated Delayed Attenuation Strategies for Salmonella enterica Serovar Typhi Vaccine Vectors in Neonatal and Infant Mice." Clinical and Vaccine Immunology 20, no. 6 (2013): 931–44. http://dx.doi.org/10.1128/cvi.00003-13.

Full text

Abstract:

ABSTRACTWe developed regulated delayed attenuation strategies forSalmonellavaccine vectors. In this study, we evaluated the combination of these strategies in recombinant attenuatedSalmonella entericaserovar Typhi andSalmonella entericaserovar Typhimurium vaccine vectors with similar genetic backgroundsin vitroandin vivo. Our goal is to develop a vaccine to preventStreptococcus pneumoniaeinfection in newborns; thus, all strains delivered a pneumococcal antigen PspA and the impact of maternal antibodies was evaluated. The results showed that all strains with the regulated delayed attenuated phe

APA, Harvard, Vancouver, ISO, and other styles

5

Juárez-Rodríguez, María Dolores, Jiseon Yang, Rebin Kader, Praveen Alamuri, Roy Curtiss, and Josephine E. Clark-Curtiss. "Live Attenuated Salmonella Vaccines Displaying Regulated Delayed Lysis and Delayed Antigen Synthesis To Confer Protection against Mycobacterium tuberculosis." Infection and Immunity 80, no. 2 (2011): 815–31. http://dx.doi.org/10.1128/iai.05526-11.

Full text

Abstract:

ABSTRACTLive recombinant attenuatedSalmonellavaccine (RASV) strains have great potential to induce protective immunity againstMycobacterium tuberculosisby deliveringM. tuberculosisantigens. Recently, we reported that, in orally immunized mice, RASV strains delivering theM. tuberculosisearly secreted antigenic target 6-kDa (ESAT-6) protein and culture filtrate protein 10 (CFP-10) antigens via theSalmonellatype III secretion system (SopE amino-terminal region residues 1 to 80 with two copies of ESAT-6 and one copy of CFP-10 [SopENt80-E2C]) afforded protection against aerosol challenge withM. tub

APA, Harvard, Vancouver, ISO, and other styles

6

Montealegre, Constanza, and Peter H. Graham. "Preference in the nodulation ofPhaseolus vulgariscv. RAB39. II. Effect of delayed inoculation or low cell representation in the inoculant on nodule occupancy byRhizobium tropiciUMR1899." Canadian Journal of Microbiology 42, no. 8 (1996): 844–50. http://dx.doi.org/10.1139/m96-106.

Full text

Abstract:

Common bean (Phaseolus vulgaris L.) is a traditional crop in much of Latin America, where it is often planted into soils containing numerous, sometimes ineffective, indigenous rhizobia. The presence of these indigenous organisms can limit response to inoculation. Because of this, we have sought bean cultivars that will nodulate preferentially with the inoculant strain, and have previously reported on the preference between the bean cultivar RAB39 and strains of Rhizobium tropici. We have detailed this interaction using the inoculant-quality strain UMR1899. In the present study the root tip mar

APA, Harvard, Vancouver, ISO, and other styles

7

Biddle, F. G., S. A. Eden, J. S. Rossler, and B. A. Eales. "Sex and death in the mouse: genetically delayed reproduction and senescence." Genome 40, no. 2 (1997): 229–35. http://dx.doi.org/10.1139/g97-032.

Full text

Abstract:

A mammalian model of genetically postponed aging would be an important tool to test not only different mechanisms of aging but also the predictive value of various biomarkers of the aging process. Under conventional conditions, the historical strains of the laboratory mouse produce their first litter between 9 and 13 weeks of age and have a median time of death in their 2nd year. Our POSCH-2 strain, which was derived from wild-caught Mus musculus domesticus, produces its first litter in the current breeding generations at approximately 47 weeks of age and continues to breed throughout its 2nd

APA, Harvard, Vancouver, ISO, and other styles

8

Luong, Thanh T., Mei G. Lei, and Chia Y. Lee. "Staphylococcus aureus Rbf Activates Biofilm Formation In Vitro and Promotes Virulence in a Murine Foreign Body Infection Model." Infection and Immunity 77, no. 1 (2008): 335–40. http://dx.doi.org/10.1128/iai.00872-08.

Full text

Abstract:

ABSTRACT We previously identified Rbf as an activator for biofilm formation on polystyrene surfaces in Staphylococcus aureus strain 8325-4. However, strain 8325-4 contains genetic mutations that may affect biofilm formation. To extend the observation to other strains, we used strain Newman, a weak biofilm producer, and strain UAMS-1, an osteomyelitis clinical strain, in this study. We found that mutations in the chromosomal rbf gene did not affect biofilm formation on polystyrene surfaces in these strains, but transformants of these strains carrying a multiple-copy plasmid containing the rbf g

APA, Harvard, Vancouver, ISO, and other styles

9

Abriouel, Hikmate, Mercedes Maqueda, Antonio Gálvez, Manuel Martínez-Bueno, and Eva Valdivia. "Inhibition of Bacterial Growth, Enterotoxin Production, and Spore Outgrowth in Strains of Bacillus cereus by Bacteriocin AS-48." Applied and Environmental Microbiology 68, no. 3 (2002): 1473–77. http://dx.doi.org/10.1128/aem.68.3.1473-1477.2002.

Full text

Abstract:

ABSTRACT Bacteriocin AS-48 showed high bactericidal activity for mesophilic and psychrotrophic strains of Bacillus cereus over a broad pH range. AS-48 inhibition of the enterotoxin-producing strain LWL1 was enhanced by sodium nitrite, sodium lactate, and sodium chloride. The latter also enhanced AS-48 activity against strain CECT 131. Bacterial growth and enterotoxin production by strain LWL1 were completely inhibited at bacteriocin concentrations of 7.5 μg/ml. At subinhibitory bacteriocin concentrations, enterotoxin production decreased markedly and sporulation was delayed. Intact spores were

APA, Harvard, Vancouver, ISO, and other styles

10

Collop, Andrew C., A. (Tom) Scarpas, Cor Kasbergen, and Arian de Bondt. "Development and Finite Element Implementation of Stress-Dependent Elastoviscoplastic Constitutive Model with Damage for Asphalt." Transportation Research Record: Journal of the Transportation Research Board 1832, no. 1 (2003): 96–104. http://dx.doi.org/10.3141/1832-12.

Full text

Abstract:

The development and finite element (FE) implementation of a stress-dependent elastoviscoplastic constitutive model with damage for asphalt is described. The model includes elastic, delayed elastic, and viscoplastic components. The strains (and strain rates) for each component are additive, whereas they share the same stress (i.e., a series model). This formulation was used so that a stress-based nonlinearity and sensitivity to confinement could be introduced into the viscoplastic component without affecting the behavior of the elastic and delayed elastic components. A simple continuum damage m

APA, Harvard, Vancouver, ISO, and other styles

11

Setlow, Barbara, Kelly A. McGinnis, Katerina Ragkousi, and Peter Setlow. "Effects of Major Spore-Specific DNA Binding Proteins on Bacillus subtilis Sporulation and Spore Properties." Journal of Bacteriology 182, no. 24 (2000): 6906–12. http://dx.doi.org/10.1128/jb.182.24.6906-6912.2000.

Full text

Abstract:

ABSTRACT Sporulation of a Bacillus subtilis strain (termed α− β−) lacking the majority of the α/β-type small, acid-soluble spore proteins (SASP) that are synthesized in the developing forespore and saturate spore DNA exhibited a number of differences from that of the wild-type strain, including delayed forespore accumulation of dipicolinic acid, overexpression of forespore-specific genes, and delayed expression of at least one mother cell-specific gene turned on late in sporulation, although genes turned on earlier in the mother cell were expressed normally in α− β− strains. The sporulation de

APA, Harvard, Vancouver, ISO, and other styles

12

Hopkins, D. L. "Biological Control of Pierce's Disease in the Vineyard with Strains of Xylella fastidiosa Benign to Grapevine." Plant Disease 89, no. 12 (2005): 1348–52. http://dx.doi.org/10.1094/pd-89-1348.

Full text

Abstract:

Naturally occurring strains of Xylella fastidiosa Wells et al. that were weakly virulent or aviru-lent to grapevine were inoculated into the lower internodes of Vitis vinifera L. cv. Carignane plants in the greenhouse and challenge inoculated with pathogenic strains 2 weeks later. Several strains provided some reduction in symptom development. Most effective in preventing or slowing the development of Pierce's disease in the greenhouse tests were a strain from sycamore and two from elderberry. In a 2-year test on ‘Himrod’ grape in the vineyard, strain Syc86-1 (from sycamore), but not strain PD

APA, Harvard, Vancouver, ISO, and other styles

13

Ohtsu, Toshihiro, Ken Haruma, Yumiko Ide, and Atsushi Takagi. "The Effect of Continuous Intake of Lactobacillus gasseri OLL2716 on Mild to Moderate Delayed Gastric Emptying: A Randomized Controlled Study." Nutrients 13, no. 6 (2021): 1852. http://dx.doi.org/10.3390/nu13061852.

Full text

Abstract:

Probiotics have been suggested to be effective for functional dyspepsia, but their effect on gastric motility is not clear. We evaluated the effect of Lactobacillus gasseri OLL2716 (LG21 strain) on mild to moderate delayed gastric emptying by a double-blind, parallel-group, placebo-controlled, randomized trial. Participants (n = 28) were randomly assigned to ingest LG21 strain-containing yogurt (LG21 strain group) or LG21 strain-free yogurt (placebo group) for 12 weeks. The 13C gastric emptying breath test was performed to measure the gastric emptying rate over time following ingestion of a li

APA, Harvard, Vancouver, ISO, and other styles

14

Aili, A., J. M. Torrenti, J. P. Sellin, J. F. Barthelemy, and M. Vandamme. "On the long-term delayed strain of concrete structures." Cement and Concrete Research 165 (March 2023): 107086. http://dx.doi.org/10.1016/j.cemconres.2022.107086.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Yasuda, Shumpei P., Yuki Miyasaka, Xuehan Hou, et al. "Two Loci Contribute to Age-Related Hearing Loss Resistance in the Japanese Wild-Derived Inbred MSM/Ms Mice." Biomedicines 10, no. 9 (2022): 2221. http://dx.doi.org/10.3390/biomedicines10092221.

Full text

Abstract:

An MSM/Ms strain was established using Japanese wild mice, which exhibit resistance to several phenotypes associated with aging, such as obesity, inflammation, and tumorigenesis, compared to common inbred mouse strains. MSM/Ms strain is resistant to age-related hearing loss, and their auditory abilities are sustained for long durations. The age-related hearing loss 3 (ahl3) locus contributes to age-related hearing in MSM/Ms strain. We generated ahl3 congenic strains by transferring a genomic region on chromosome 17 from MSM/Ms mice into C57BL/6J mice. Although C57BL/6J mice develop age-related

APA, Harvard, Vancouver, ISO, and other styles

16

Wedlock, D. Neil, Frank E. Aldwell, Desmond M. Collins, Geoffrey W. de Lisle, Theresa Wilson, and Bryce M. Buddle. "Immune Responses Induced in Cattle by Virulent and AttenuatedMycobacterium bovis Strains: Correlation of Delayed-Type Hypersensitivity with Ability of Strains To Grow in Macrophages." Infection and Immunity 67, no. 5 (1999): 2172–77. http://dx.doi.org/10.1128/iai.67.5.2172-2177.1999.

Full text

Abstract:

ABSTRACT Comparison of immune responses induced in cattle by virulent and attenuated strains of Mycobacterium bovis will assist in identifying responses associated with resistance or susceptibility to disease. Four strains of M. bovis, one which is virulent in guinea pigs (WAg201) and three which are attenuated in guinea pigs (an isoniazid-resistant strain [WAg405], ATCC 35721, and BCG) were compared for their abilities to induce immune responses in cattle and to grow in bovine lung alveolar macrophage cultures. Extensive macroscopic lesions were found only in cattle inoculated with the virule

APA, Harvard, Vancouver, ISO, and other styles

17

Etchebar, Christophe, Danièle Trigalet-Demery, Frédérique van Gijsegem, Jacques Vasse, and André Trigalet. "Xylem Colonization by an HrcV¯ Mutant of Ralstonia solanacearum Is a Key Factor for the Efficient Biological Control of Tomato Bacterial Wilt." Molecular Plant-Microbe Interactions® 11, no. 9 (1998): 869–77. http://dx.doi.org/10.1094/mpmi.1998.11.9.869.

Full text

Abstract:

Microscopic studies of the colonization of the vascular tissues of tomato by an HrcV¯ (formerly HrpO¯) mutant strain of Ralstonia solanacearum were carried out after either root inoculation of the mutant strain alone or delayed challenge inoculation by a pathogenic strain. The use of two different marker genes, lacZ and uidA, introduced into either mutant or wild-type strains, respectively, permitted histological observation for the presence of both strains simultaneously. In roots, both strains could be found together in infected root tips and in lateral root emergence sites (lateral root cra

APA, Harvard, Vancouver, ISO, and other styles

18

Reifsnyder, Peter C., Austen Te, and David E. Harrison. "Differential Effects of Rapamycin on Glucose Metabolism in Nine Inbred Strains." Journals of Gerontology: Series A 75, no. 1 (2019): 50–57. http://dx.doi.org/10.1093/gerona/glz157.

Full text

Abstract:

Abstract Studies in mice suggest that rapamycin has a negative impact on glucose homeostasis by inducing insulin resistance. However, results have been inconsistent and difficult to assess because the strains, methods of treatment, and analysis vary among studies. Using a consistent protocol, we surveyed nine inbred strains of mice for the effect of rapamycin on various aspects of glucose metabolism. Across all strains, rapamycin significantly delayed glucose clearance after challenge. However, rapamycin showed no main effect on systemic insulin sensitivity. Analysis of individual strains show

APA, Harvard, Vancouver, ISO, and other styles

19

Derckel, Jean-Paul, Fabienne Baillieul, Sébastien Manteau, et al. "Differential Induction of Grapevine Defenses by Two Strains of Botrytis cinerea." Phytopathology® 89, no. 3 (1999): 197–203. http://dx.doi.org/10.1094/phyto.1999.89.3.197.

Full text

Abstract:

Even though Botrytis cinerea, the causal agent of gray mold, is a highly variable fungus with strains displaying very different degrees of virulence toward one given host plant species, no study has yet shown any correlation between the lack of aggressiveness of one given strain and its ability to stimulate a defense response from its host. Strains of B. cinerea collected from different host plant species were screened for their pathogenicity on grapevine to select two strains with similar morphological characteristics but different levels of virulence. In grapevine leaves, the less aggressive

APA, Harvard, Vancouver, ISO, and other styles

20

Wang, Shifeng, Huoying Shi, Yuhua Li, et al. "A Colanic Acid Operon Deletion Mutation Enhances Induction of Early Antibody Responses by Live Attenuated Salmonella Vaccine Strains." Infection and Immunity 81, no. 9 (2013): 3148–62. http://dx.doi.org/10.1128/iai.00097-13.

Full text

Abstract:

ABSTRACTColanic acid (CA) is a common exopolysaccharide produced by many genera in theEnterobacteriaceae. It is critical for biofilm formation on HEp-2 cells and on chicken intestinal tissue bySalmonella. In this study, we generated different CA synthesis gene mutants and evaluated the immune responses induced by these mutants. One of these mutations, Δ(wza-wcaM)8, which deleted the whole operon for CA synthesis, was introduced into twoSalmonellavaccine strains attenuated by auxotrophic traits or by the regulated delayed attenuation strategy (RDAS). The mice immunized with the auxotrophicSalmo

APA, Harvard, Vancouver, ISO, and other styles

21

Su, Yu, Xuyi Wang, Yuanli Luo, Huan Jiang, Guiting Tang, and Huai Liu. "The Catalase Gene MrCat1 Contributes to Oxidative Stress Tolerance, Microsclerotia Formation, and Virulence in the Entomopathogenic Fungus Metarhizium rileyi." Journal of Fungi 10, no. 8 (2024): 543. http://dx.doi.org/10.3390/jof10080543.

Full text

Abstract:

Catalases play a crucial role in the metabolism of reactive oxygen species (ROS) by converting H2O2 into molecular oxygen and water. They also contribute to virulence and fungal responses to various stresses. Previously, the MrCat1-deletion mutant (ΔMrCat1) was generated using the split-marker method in Metarhizium rileyi. In this study, the Cat1 gene was identified, and its function was evaluated. Under normal culture conditions, there were no significant differences in colony growth or dimorphic switching between ΔMrCat1 and the wild-type (WT) strains. However, under oxidative stress, the co

APA, Harvard, Vancouver, ISO, and other styles

22

Feng, Jia-Xun, Zhi-Zhong Song, Cheng-Jie Duan, et al. "The xrvA gene of Xanthomonas oryzae pv. oryzae, encoding an H-NS-like protein, regulates virulence in rice." Microbiology 155, no. 9 (2009): 3033–44. http://dx.doi.org/10.1099/mic.0.028910-0.

Full text

Abstract:

Xanthomonas oryzae pv. oryzae (Xoo) causes bacterial blight disease in rice, one of the most serious rice diseases. The xrvA gene from Xoo strain 13751 encodes a protein containing a histone-like nucleoid-structuring protein (H-NS) domain. The expression of xrvA in strain 13751 was enhanced in XOM2 minimal medium. Mutation of the xrvA gene of strain 13751 led to a significant reduction in virulence in the host plant rice, a delayed hypersensitive response in the nonhost castor-oil plant, a decrease in extracellular polysaccharide and diffusible signal factor production, and an increase in intr

APA, Harvard, Vancouver, ISO, and other styles

23

González, Laura, Álvaro Gaute, Jokin Rico, and Carlos Thomas. "Effect of Fibre Reinforcement on Creep in Early Age Concrete." Applied Sciences 12, no. 1 (2021): 257. http://dx.doi.org/10.3390/app12010257.

Full text

Abstract:

This research analyses the strain behaviour of fibre-reinforced concrete (FRC) in the event of a creep episode. The analysis of creep experienced by FRC specimens during the test reflects better performance than that predicted by the EHE-08 standard. The authors propose a formulation for the evaluation of creep strain undergone by FRC. During the research, the evolution of the modulus of elasticity of FRC after a creep episode is analysed. After the test campaign, it can be concluded that FRC loaded at an earlier age stiffens after a creep episode. After the creep test is completed, the delaye

APA, Harvard, Vancouver, ISO, and other styles

24

Scibilia, K. L., F. V. Hebard, and L. Shain. "Conidia of hypovirulent strains of Cryphonectriaparasitica differ in their potential for biocontrol of chestnut blight." Canadian Journal of Forest Research 22, no. 9 (1992): 1338–42. http://dx.doi.org/10.1139/x92-178.

Full text

Abstract:

Conidia from eight hypovirulent strains of Cryphonectriaparasitica (Murr.) Barr were suspended in water and applied to the bark of American chestnut (Castaneadentata (Marsh.) Borkh.) trees. Cankers were initiated with mycelium of virulent strains isogenic to the applied conidia. Hypovirulent strains differed significantly in the ability of their conidia to putatively convert isogenic virulent strains in cankers, as indicated by the recovery of cultures with hypovirulent morphology from challenged cankers. A tank mix of conidia from two hypovirulent strains in different conversion groups putati

APA, Harvard, Vancouver, ISO, and other styles

25

ia Chen, Dan, and Zhiting Xu. "Global dynamics of a delayed diffusive two-strain disease model." Differential Equations & Applications, no. 1 (2016): 99–122. http://dx.doi.org/10.7153/dea-08-07.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Cole, Andrew. "Influenza vaccine is delayed by problems in growing virus strain." BMJ 333, no. 7571 (2006): 721.2. http://dx.doi.org/10.1136/bmj.333.7571.721-a.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Wang, Shaoli, Achun Zhang, and Fei Xu. "Dynamical analysis for delayed virus infection models with cell-to-cell transmission and density-dependent diffusion." International Journal of Biomathematics 13, no. 07 (2020): 2050060. http://dx.doi.org/10.1142/s1793524520500606.

Full text

Abstract:

In this paper, certain delayed virus dynamical models with cell-to-cell infection and density-dependent diffusion are investigated. For the viral model with a single strain, we have proved the well-posedness and studied the global stabilities of equilibria by defining the basic reproductive number [Formula: see text] and structuring proper Lyapunov functional. Moreover, we found that the infection-free equilibrium is globally asymptotically stable if [Formula: see text], and the infection equilibrium is globally asymptotically stable if [Formula: see text]. For the multi-strain model, we found

APA, Harvard, Vancouver, ISO, and other styles

28

Goto, Kazuhiro. "Strain differences between C57Bl/6 and DBA/2 mice (Mus musculus) in delayed matching and nonmatching-to-position tasks: impact of sample responses and delay intervals." PeerJ 13 (March 24, 2025): e19200. https://doi.org/10.7717/peerj.19200.

Full text

Abstract:

Background Spatial working memory is commonly assessed in rodents using delayed matching-to-position (DMTP) and delayed nonmatching-to-position (DNMTP) tasks. Although these tasks are widely used to examine memory function, particularly in relation to delay intervals and response requirements, strain differences in task performance remain underexplored. This study investigates spatial working memory in two widely used mouse strains, C57BL/6 and DBA/2, using these tasks. Methods Mice were trained and tested on the DNMTP task first, followed by the DMTP task. Both tasks were conducted with varyi

APA, Harvard, Vancouver, ISO, and other styles

29

Alexandrova, Natalya A., Maya I. Zaslavskaya, Irina V. Soloveva, Anna G. Tochilina, and Irina V. Belova. "EVALUATION OF ANTI-CANDIDA ACTIVITY OF METABOLITES OF ENTEROCOCCAL CLINICAL ISOLATES." Russian Clinical Laboratory Diagnostics 64, no. 11 (2019): 690–92. http://dx.doi.org/10.18821/0869-2084-2019-64-11-690-692.

Full text

Abstract:

When studying the effect of the metabolic products of clinical isolates of enterococci on the viability of Candida albicans, it was found that metabolites of all tested strains of Enterococcus faecium, E. faecalis had a fungistatic effect. At the same time a reliable fungicidal effect is a strain-specific feature. It is better to use the method of delayed antagonism on double-layer agar to assess the antifungal effect of enterococcal metabolism products.

APA, Harvard, Vancouver, ISO, and other styles

30

Minz Dub, Anna, Leonie Kokkelink, Bettina Tudzynski, Paul Tudzynski, and Amir Sharon. "Involvement of Botrytis cinerea Small GTPases BcRAS1 and BcRAC in Differentiation, Virulence, and the Cell Cycle." Eukaryotic Cell 12, no. 12 (2013): 1609–18. http://dx.doi.org/10.1128/ec.00160-13.

Full text

Abstract:

ABSTRACTSmall GTPases of the Ras superfamily are highly conserved proteins that are involved in various cellular processes, in particular morphogenesis, differentiation, and polar growth. Here we report on the analysis of RAS1 and RAC homologues from the gray mold fungusBotrytis cinerea. We show that these small GTPases are individually necessary for polar growth, reproduction, and pathogenicity, required for cell cycle progression through mitosis (BcRAC), and may lie upstream of the stress-related mitogen-activated protein kinase (MAPK) signaling pathway.bcras1andbcracdeletion strains had red

APA, Harvard, Vancouver, ISO, and other styles

31

Harrison, Judith, Alexandre Jamet, Cecilia I. Muglia, et al. "Glutathione Plays a Fundamental Role in Growth and Symbiotic Capacity of Sinorhizobium meliloti." Journal of Bacteriology 187, no. 1 (2005): 168–74. http://dx.doi.org/10.1128/jb.187.1.168-174.2005.

Full text

Abstract:

ABSTRACT Rhizobia form a symbiotic relationship with plants of the legume family to produce nitrogen-fixing root nodules under nitrogen-limiting conditions. We have examined the importance of glutathione (GSH) during free-living growth and symbiosis of Sinorhizobium meliloti. An S. meliloti mutant strain (SmgshA) which is unable to synthesize GSH due to a gene disruption in gshA, encoding the enzyme for the first step in the biosynthesis of GSH, was unable to grow under nonstress conditions, precluding any nodulation. In contrast, an S. meliloti strain (SmgshB) with gshB, encoding the enzyme i

APA, Harvard, Vancouver, ISO, and other styles

32

Dr, .Ehab Abdulameer Kadum, and Ali Abdulameer Dr. "Myocardial Viability Assessment by Dobutamine Echocardiography using Speckle-Tracking: Comparison with cardiac MRI delay enhancement." Sarcouncil Journal of Medicine and Surgery 3, no. 1 (2024): 7–33. https://doi.org/10.5281/zenodo.10523253.

Full text

Abstract:

<strong>Background</strong>: The use of myocardial strain imaging during dobutamine echocardiography may facilitate the prediction of myocardial viability. speckletracking echocardiography (STE) are used for myocardial strain measurement, it needs validation for prediction of viability . <strong>Aim of the study</strong>: To determine the accuracy of STE-based measurements of myocardial strain for the detection of myocardial viability before revascularization using  MRI delayed enhancement imaging as agold standard. <strong>Methods</strong>: The study included 20 patients (14 males , 6 fe

APA, Harvard, Vancouver, ISO, and other styles

33

Lv, Huibin, Ray T. Y. So, Qi Wen Teo, et al. "Neutralizing Antibody Response to Sarbecovirus Is Delayed in Sequential Heterologous Immunization." Viruses 14, no. 7 (2022): 1382. http://dx.doi.org/10.3390/v14071382.

Full text

Abstract:

Antigenic imprinting, which describes the bias of the antibody response due to previous immune history, can influence vaccine effectiveness. While this phenomenon has been reported for viruses such as influenza, there is little understanding of how prior immune history affects the antibody response to SARS-CoV-2. This study provides evidence for antigenic imprinting through immunization with two Sarbecoviruses, the subgenus that includes SARS-CoV-2. Mice were immunized subsequently with two antigenically distinct Sarbecovirus strains, namely SARS-CoV-1 and SARS-CoV-2. We found that sequential

APA, Harvard, Vancouver, ISO, and other styles

34

Cazalets, Jean-René, Marie Gardette, and Gérard Hilaire. "Locomotor Network Maturation Is Transiently Delayed in the MAOA-Deficient Mouse." Journal of Neurophysiology 83, no. 4 (2000): 2468–70. http://dx.doi.org/10.1152/jn.2000.83.4.2468.

Full text

Abstract:

In vivo and in vitro experiments were performed in control (C3H) and monoamine oxidase A (MAOA)-deficient (Tg8) neonatal mice to determine whether MAOA deficiency affected spinal locomotor network maturation. Comparing the swimming behaviors at birth in C3H mice with those in Tg8 mice revealed a delayed role for the hindlimbs in Tg8 swimming, even though adult swimming behavior was acquired at postnatal day 14 (P14) in both strains. Analyzing the locomotor network activity in vitro showed that serotonin (5-HT) induced and modulated locomotor-like discharges in hindlimb ventral roots of C3H but

APA, Harvard, Vancouver, ISO, and other styles

35

Bubeck, Sarah S., Angelene M. Cantwell, and Peter H. Dube. "Delayed Inflammatory Response to Primary Pneumonic Plague Occurs in Both Outbred and Inbred Mice." Infection and Immunity 75, no. 2 (2006): 697–705. http://dx.doi.org/10.1128/iai.00403-06.

Full text

Abstract:

ABSTRACT Yersinia pestis is the causative agent of plague, a disease that can manifest as either bubonic or pneumonic plague. An interesting feature of plague is that it is a rapidly progressive disease, suggesting that Y. pestis either evades and/or suppresses the innate immune response to infection. Therefore, the early host response during the course of primary pneumonic plague was investigated in two mouse strains, the outbred strain CD1 and the inbred strain C57BL/6. A comparative analysis of the course of disease in these two strains of mice indicated that they are susceptible to intrana

APA, Harvard, Vancouver, ISO, and other styles

36

Morgan, Sydney C., Jade J. Haggerty, Britney Johnston, Vladimir Jiranek, and Daniel M. Durall. "Response to Sulfur Dioxide Addition by Two Commercial Saccharomyces cerevisiae Strains." Fermentation 5, no. 3 (2019): 69. http://dx.doi.org/10.3390/fermentation5030069.

Full text

Abstract:

Sulfur dioxide (SO2) is an antioxidant and antimicrobial agent used in winemaking. Its effects on spoilage microorganisms has been studied extensively, but its effects on commercial Saccharomyces cerevisiae strains, the dominant yeast in winemaking, require further investigation. To our knowledge, no previous studies have investigated both the potential SO2 resistance mechanisms of commercial yeasts as well as their production of aroma-active volatile compounds in response to SO2. To study this, fermentations of two commercial yeast strains were conducted in the presence (50 mg/L) and absence

APA, Harvard, Vancouver, ISO, and other styles

37

Jeong, Kyucheol, Jaewook Lee, and Jonghun Yoon. "Experimental Investigation of Delayed Fracture Initiation in Advanced High-Strength Steel Under Accelerated Bending." Materials 18, no. 14 (2025): 3415. https://doi.org/10.3390/ma18143415.

Full text

Abstract:

Predicting bending fractures in advanced high-strength steel (AHSS) is challenging due to complex microstructural behaviors and strain rate dependencies, particularly in industrial forming processes. Current models and standards primarily focus on quasi-static tension or slow bending speeds, leaving a gap in understanding the accelerated failure of AHSS without necking. In this study, direct bending experiments were conducted on dual-phase, complex-phase, and martensitic AHSS grades under varying bending speeds and radii. Since the bending crack is irrelevant to the load drop, surface crack ev

APA, Harvard, Vancouver, ISO, and other styles

38

Oliveira, Fernanda Bellaniza Caminha de, Vanessa Paola Alves Sampaio de Sá Freire, Sharton Vinicius Antunes Coelho, et al. "ZIKV Strains Elicit Different Inflammatory and Anti-Viral Responses in Microglia Cells." Viruses 15, no. 6 (2023): 1250. http://dx.doi.org/10.3390/v15061250.

Full text

Abstract:

In recent years, the Zika Virus (ZIKV) has caused pandemic outbreaks associated with a high rate of congenital ZIKV syndrome (CZS). Although all strains associated with worldwide outbreaks derive from the Asian lineage, the reasons for their enhanced spread and severity are not fully understood. In this study, we conducted a comparative analysis of miRNAs (miRNA-155/146a/124) and their cellular targets (SOCS1/3, SHP1, TRAF6, IRAK1), as well as pro- and anti-inflammatory and anti-viral cytokines (IL-6, TNF-α, IFN-γ, IL-10, and IFN-β) and peroxisome proliferator-activated receptor γ (PPAR-γ) exp

APA, Harvard, Vancouver, ISO, and other styles

39

Cheville, Norman F., Allen E. Jensen, David C. Morfitt, and Thomas J. Stabel. "Cutaneous delayed hypersensitivity reactions of cattle vaccinated with mutant strains of Brucella abortus, using brucellins prepared from various brucellar strains." American Journal of Veterinary Research 55, no. 9 (1994): 1261–66. http://dx.doi.org/10.2460/ajvr.1994.55.09.1261.

Full text

Abstract:

Summary Cutaneous reactivity to brucellin was evaluated in 10-month-old heifers vaccinated with low-virulence mutant strains of Brucella abortus and was compared with brucellin reactions in postparturient cows with active brucellosis. In the cows, the cutaneous lesion was characterized microscopically as severe, acute, serofibrinous vasculitis; dermal lesions at 6, 12, 25, and 48 hours after brucellin injection consisted of endothelial activation and perivascular exudation that led to progressive accumulation of fibrin, monocytes, macrophages, and lymphocytes. In vaccinated heifers, cutaneous

APA, Harvard, Vancouver, ISO, and other styles

40

Puzrin, Alexander M., Thierry Faug, and Itai Einav. "The mechanism of delayed release in earthquake-induced avalanches." Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences 475, no. 2227 (2019): 20190092. http://dx.doi.org/10.1098/rspa.2019.0092.

Full text

Abstract:

Snow avalanches can be triggered by strong earthquakes. Most existing models assume that snow slab avalanches happen simultaneously during or immediately after their triggering. Therefore, they cannot explain the plausibility of delayed avalanches that are released minutes to hours after a quake. This paper establishes the basic mechanism of delays in earthquake-induced avalanche release using a novel analytical model that yields dynamics consistent with three documented cases, including two from Western Himalaya and one from central Italy. The mechanism arises from the interplay between creep

APA, Harvard, Vancouver, ISO, and other styles

41

Podrzaj, Lucija, Johanna Burtscher, Franziska Küller, and Konrad J. Domig. "Strain-Dependent Cheese Spoilage Potential of Clostridium tyrobutyricum." Microorganisms 8, no. 11 (2020): 1836. http://dx.doi.org/10.3390/microorganisms8111836.

Full text

Abstract:

Clostridium tyrobutyricum, a Gram-positive, anaerobic, spore-forming bacterium, is considered as one of the main causative agents for spoilage of hard and semihard cheeses. Growth of C. tyrobutyricum in cheese is critically influenced by ripening temperature and time, pH, salt and lactic acid concentration, moisture and fat content, and the presence of other microorganisms. Previous studies revealed high intraspecies diversity of C. tyrobutyricum strains and variable tolerance toward pH, temperatures, and salt concentrations. These findings indicate that strain-dependent characteristics may be

APA, Harvard, Vancouver, ISO, and other styles

42

Xiong, Huizhong, Rebecca A. Carter, Ingrid M. Leiner, et al. "Distinct Contributions of Neutrophils and CCR2+Monocytes to Pulmonary Clearance of Different Klebsiella pneumoniae Strains." Infection and Immunity 83, no. 9 (2015): 3418–27. http://dx.doi.org/10.1128/iai.00678-15.

Full text

Abstract:

Klebsiella pneumoniaeis a common respiratory pathogen, with some strains having developed broad resistance to clinically available antibiotics. Humans can become infected with many differentK. pneumoniaestrains that vary in genetic background, antibiotic susceptibility, capsule composition, and mucoid phenotype. Genome comparisons have revealed differences betweenK. pneumoniaestrains, but the impact of genomic variability on immune-mediated clearance of pneumonia remains unclear. Experimental studies of pneumonia in mice have used the rodent-adapted 43816 strain ofK. pneumoniaeand demonstrated

APA, Harvard, Vancouver, ISO, and other styles

43

González-Mederos, Pedro, Jennifer Rodríguez-Guerra, Jesús E. González, Alberto Picardo, and Yadir Torres. "A Finite Element Analysis of a New Dental Implant Design: The Influence of the Diameter, Length, and Material of an Implant on Its Biomechanical Behavior." Materials 18, no. 12 (2025): 2692. https://doi.org/10.3390/ma18122692.

Full text

Abstract:

It is widely recognized that excessive stress and/or strain can lead to peri-implant bone atrophy; therefore, the clinical success of dental implants is intrinsically related to their biomechanical behavior. This study evaluates the influence of the diameter, length, and material [Ti6Al4V (α+β Ti) and Ti35Nb7Zr5Ta (β-Ti)] of a novel cylindrical dental implant on stress and strain levels within maxillary bone of type II quality. The implant design aims to ensure an appropriate distribution of stresses and strains within the peri-implant bone structures (cortical and trabecular bones) while also

APA, Harvard, Vancouver, ISO, and other styles

44

Lunne, Tom, Toralv Berre, Knut H. Andersen, Stein Strandvik, and Morten Sjursen. "Effects of sample disturbance and consolidation procedures on measured shear strength of soft marine Norwegian clays." Canadian Geotechnical Journal 43, no. 7 (2006): 726–50. http://dx.doi.org/10.1139/t06-040.

Full text

Abstract:

After many decades of research, the issue of sample disturbance is still important as regards to determining reliable and representative soil parameters for foundation design in soft clays. Parallel laboratory tests have been carried out on high-quality block samples and ordinary piston tube samples from 12 deposits of soft Norwegian marine clays. Undrained triaxial and direct simple shear (DSS) tests on samples reconsolidated to the in situ effective stresses show that sample disturbance has a significant effect on the measured stress–strain–strength behaviour: the more disturbed the sample,

APA, Harvard, Vancouver, ISO, and other styles

45

Kaymakamzade, Bilgen, and Evren Hincal. "Two-strain epidemic model with two vaccinations and two time delayed." Quality & Quantity 52, S1 (2017): 695–709. http://dx.doi.org/10.1007/s11135-017-0647-8.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Chen, Zhenwu, and Zhiting Xu. "A delayed diffusive influenza model with two-strain and two vaccinations." Applied Mathematics and Computation 349 (May 2019): 439–53. http://dx.doi.org/10.1016/j.amc.2018.12.065.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Shen, Xixun, Congcong Zhang, Tao Zeng, Danhong Cheng, and Jianshe Lian. "Understanding the microscopic deformation mechanism and macroscopic mechanical behavior of nanocrystalline Ni by the long-term stress relaxation test." International Journal of Modern Physics B 28, no. 20 (2014): 1450124. http://dx.doi.org/10.1142/s0217979214501240.

Full text

Abstract:

The long-term stress relaxation tests with a relaxation time of about 7 h are performed on the bulk dense nanocrystalline Ni (with a mean grain size of 27 nm) pre-deformed at strain rate from 4.17 s-1- 4.17 × 10-6 s-1, where a phenomenon that the initial relaxation behavior of nc Ni depends on itself deformation history. That is, the nc Ni s pre-deformed at higher strain rate (not less than 4.17 × 10-3 s-1) exhibit a three-staged relaxation process from the initial near linear rapidly stress delayed (LRSD) stage and the subsequent lumber nonlinear stress delayed (LNSD) one and the final near l

APA, Harvard, Vancouver, ISO, and other styles

48

Dollé, Jean-Pierre, Barclay Morrison, Rene S. Schloss, and Martin L. Yarmush. "Brain-on-a-chip microsystem for investigating traumatic brain injury: Axon diameter and mitochondrial membrane changes play a significant role in axonal response to strain injuries." TECHNOLOGY 02, no. 02 (2014): 106–17. http://dx.doi.org/10.1142/s2339547814500095.

Full text

Abstract:

Diffuse axonal injury (DAI) is a devastating consequence of traumatic brain injury, resulting in significant axon and neuronal degeneration. Currently, therapeutic options are limited. Using our brain-on-a-chip device, we evaluated axonal responses to DAI. We observed that axonal diameter plays a significant role in response to strain injury, which correlated to delayed elasticity and inversely correlated to axonal beading and axonal degeneration. When changes in mitochondrial membrane potential (MMP) were monitored an applied strain injury threshold was noted, below which delayed hyperpolariz

APA, Harvard, Vancouver, ISO, and other styles

49

Kong, Qingke, Qing Liu, Kenneth L. Roland, and Roy Curtiss. "Regulated Delayed Expression of rfaH in an Attenuated Salmonellaenterica Serovar Typhimurium Vaccine Enhances Immunogenicity of Outer Membrane Proteins and a Heterologous Antigen." Infection and Immunity 77, no. 12 (2009): 5572–82. http://dx.doi.org/10.1128/iai.00831-09.

Full text

Abstract:

ABSTRACT RfaH is a transcriptional antiterminator that reduces the polarity of long operons encoding secreted and surface-associated cell components of Salmonella enterica serovar Typhimurium, including O antigen and lipopolysaccharide core sugars. A ΔrfaH mutant strain is attenuated in mice (50% lethal dose [LD50], >108 CFU). To examine the potential for using rfaH in conjunction with other attenuating mutations, we designed a series of strains in which we replaced the native rfaH promoter with the tightly regulated arabinose-dependent araC PBAD promoter so that rfaH expression was depende

APA, Harvard, Vancouver, ISO, and other styles

50

Surendran, Naveen, Elizabeth Hiltbold, Nammalwar Sriranganathan, et al. "The significance of TLRs in Brucella mediated dendritic cell activation in vitro and pulmonary clearance in vivo (42.16)." Journal of Immunology 184, no. 1_Supplement (2010): 42.16. http://dx.doi.org/10.4049/jimmunol.184.supp.42.16.

Full text

Abstract:

Abstract Brucellosis is a worldwide zoonoses affecting 500,000 people annually with no approved human vaccines available. Live attenuated B. abortus vaccine strain RB51 protects cattle through CD4 and CD8 T-cell mediated responses. However, there are concerns regarding its efficacy and use as a live vaccine in people. Therefore, identifying how Brucella vaccines stimulate innate and adaptive immunity is critical to enhancing vaccine efficacy. Brucella stimulate dendritic cells (DCs) through Toll-Like Receptors (TLRs) 2, 4 and 9. In this study, to identify how rough vaccine strains stimulate DC

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!