Academic literature on the topic 'Delta inulin'

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Journal articles on the topic "Delta inulin"

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Afinjuomo, Franklin, Thomas G. Barclay, Ankit Parikh, et al. "Design and Characterization of Inulin Conjugate for Improved Intracellular and Targeted Delivery of Pyrazinoic Acid to Monocytes." Pharmaceutics 11, no. 5 (2019): 243. http://dx.doi.org/10.3390/pharmaceutics11050243.

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The propensity of monocytes to migrate into sites of mycobacterium tuberculosis (TB) infection and then become infected themselves makes them potential targets for delivery of drugs intracellularly to the tubercle bacilli reservoir. Conventional TB drugs are less effective because of poor intracellular delivery to this bacterial sanctuary. This study highlights the potential of using semicrystalline delta inulin particles that are readily internalised by monocytes for a monocyte-based drug delivery system. Pyrazinoic acid was successfully attached covalently to the delta inulin particles via a
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Honda-Okubo, Yoshikazu, Dale Barnard, Chun Hao Ong, Bi-Hung Peng, Chien-Te Kent Tseng, and Nikolai Petrovsky. "Severe Acute Respiratory Syndrome-Associated Coronavirus Vaccines Formulated with Delta Inulin Adjuvants Provide Enhanced Protection while Ameliorating Lung Eosinophilic Immunopathology." Journal of Virology 89, no. 6 (2014): 2995–3007. http://dx.doi.org/10.1128/jvi.02980-14.

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ABSTRACTAlthough the severe acute respiratory syndrome-associated coronavirus (SARS-CoV) epidemic was controlled by nonvaccine measures, coronaviruses remain a major threat to human health. The design of optimal coronavirus vaccines therefore remains a priority. Such vaccines present major challenges: coronavirus immunity often wanes rapidly, individuals needing to be protected include the elderly, and vaccines may exacerbate rather than prevent coronavirus lung immunopathology. To address these issues, we compared in a murine model a range of recombinant spike protein or inactivated whole-vir
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Wang, Lixin, Thomas Barclay, Yunmei Song, et al. "Investigation of the biodistribution, breakdown and excretion of delta inulin adjuvant." Vaccine 35, no. 34 (2017): 4382–88. http://dx.doi.org/10.1016/j.vaccine.2017.06.045.

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Ferrell, Kia C., Erica L. Stewart, Claudio Counoupas, et al. "Intrapulmonary vaccination with delta-inulin adjuvant stimulates non-polarised chemotactic signalling and diverse cellular interaction." Mucosal Immunology 14, no. 3 (2021): 762–73. http://dx.doi.org/10.1038/s41385-021-00379-6.

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AbstractThere is an urgent need for novel vaccination strategies to combat respiratory pathogens. Mucosal vaccine delivery is an attractive option as it directly targets the site of infection; however, preclinical development has been hindered by a lack of suitable mucosal adjuvants and a limited understanding of their immune effects in the lung environment. Herein, we define the early immune events following the intrapulmonary delivery of a vaccine incorporating the adjuvant delta-inulin. Analysis of the early inflammatory response showed vaccine-induced innate cell recruitment to lungs and l
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Murugappan, Senthil, Henderik W. Frijlink, Nikolai Petrovsky, and Wouter L. J. Hinrichs. "Enhanced pulmonary immunization with aerosolized inactivated influenza vaccine containing delta inulin adjuvant." European Journal of Pharmaceutical Sciences 66 (January 2015): 118–22. http://dx.doi.org/10.1016/j.ejps.2014.10.008.

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Wang, Lixin, Yunmei Song, Ankit Parikh, et al. "Doxorubicin-Loaded Delta Inulin Conjugates for Controlled and Targeted Drug Delivery: Development, Characterization, and In Vitro Evaluation." Pharmaceutics 11, no. 11 (2019): 581. http://dx.doi.org/10.3390/pharmaceutics11110581.

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Delta inulin, also known as microparticulate inulin (MPI), was modified by covalently attaching doxorubicin to its nanostructured surface for use as a targeted drug delivery vehicle. MPI is readily endocytosed by monocytes, macrophages, and dendritic cells and in this study, we sought to utilize this property to develop a system to target anti-cancer drugs to lymphoid organs. We investigated, therefore, whether MPI could be used as a vehicle to deliver doxorubicin selectively, thereby reducing the toxicity of this antibiotic anthracycline drug. Doxorubicin was covalently attached to the surfac
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Heddle, Robert, Paul Russo, Nikolai Petrovsky, Rory Hanna, and Anthony Smith. "Immunotherapy – 2076. A controlled study of delta inulin-adjuvanted honey bee venom immunotherapy." World Allergy Organization Journal 6 (2013): P158. http://dx.doi.org/10.1186/1939-4551-6-s1-p158.

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Hayashi, Masayuki, Taiki Aoshi, Yasunari Haseda, et al. "Advax, a Delta Inulin Microparticle, Potentiates In-built Adjuvant Property of Co-administered Vaccines." EBioMedicine 15 (February 2017): 127–36. http://dx.doi.org/10.1016/j.ebiom.2016.11.015.

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LUCACI, ANCA IOANA, SIMONA NEAGU, ROXANA COJOC, ROBERT RUGINESCU, IOAN ARDELEAN, and MĂDĂLIN ENACHE. "Benefits of understanding the enzymatic activities in saline Lake Letea in the Danube Delta." Romanian Biotechnological Letters 26, no. 2 (2021): 2448–54. http://dx.doi.org/10.25083/rbl/26.2/2448.2454.

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The purpose of this paper was to isolate halophiles from Letea saline lake and to performed a screening for industrially relevant extracellular enzymes. The investigations were conducted from October 2016 until May 2018. After a random selection of colonies that grew on the medium culture, 82 isolates were investigated. Based on their salt requirements and tolerance, it was remarked the presence of isolates belonging to halotolerant and moderate halophilic bacteria. Morphological and biochemical tests were used to characterize them. The ability of the tested isolates to produce extracellular e
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Roberts, M., M. D. Lindheimer, and J. M. Davison. "Altered glomerular permselectivity to neutral dextrans and heteroporous membrane modeling in human pregnancy." American Journal of Physiology-Renal Physiology 270, no. 2 (1996): F338—F343. http://dx.doi.org/10.1152/ajprenal.1996.270.2.f338.

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Hyperfiltration precedes renal function loss in several nephropathies. Animal studies suggest this may be due to accompanying increases in transglomerular capillary hydrostatic pressure difference (delta P) and/or altered glomerular processing of macromolecules. Renal hemodynamics increase strikingly in human pregnancy. To test the hypothesis that these alterations are not potentially harmful, clearances of inulin, p-aminohippurate, and neutral dextrans were measured at 16- and 36-wk gestation, then 4 mo postpartum, in 11 normotensive women. Results were analyzed using two computer modeling pr
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Dissertations / Theses on the topic "Delta inulin"

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SALVATORE, ENRICO. "Utilizzo della tecnica di ultrafiltrazione per la produzione di prodotti caseari freschi low-fat e a valenza funzionale." Doctoral thesis, Università degli Studi di Cagliari, 2011. http://hdl.handle.net/11584/265917.

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La tecnica di ultrafiltrazione del latte e del siero di latte è stata utilizzata come strumento tecnologico per ottenere prodotti caseari freschi low-fat e caratterizzati da potenziali effetti benefici per la salute. La tecnica di ultrafiltrazione applicata al latte o al siero magro permette infatti di incrementare e/o standardizzare il contenuto di proteine di questi prodotti. Il latte o il siero concentrato possono così essere utilizzati in combinazione con altre frazioni del latte (come la crema), e/o con ingredienti funzionali, al fine di ottenere prodotti estremamente interessanti da un p
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Eickmeyer, David. "The Effects of Retrogressive Thaw Slump Development on Persistent Organic Pollutants in Lake Sediments of the Mackenzie River Delta Uplands, NT, Canada." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/25998.

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Using a comparative spatial and temporal analysis on sediment cores from 8 lakes in the Mackenzie River Delta uplands region, NT, Canada, this study assessed how persistent organic pollutant (POP) deposition to lake sediments was affected by: (1) the presence of retrogressive thaw slumps on lake shores; and (2) changes occurring with increased autochthonous primary productivity. POPs examined included polychlorinated biphenyls (PCBs), penta- and hexachlorobenzenes (CBzs), and dichlorodiphenyltrichloroethane and metabolites (DDTs). Surface sediments of slump-affected lakes contained higher tota
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Books on the topic "Delta inulin"

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Conaty, Gerald T. The reindeer herders of the Mackenzie delta. Firefly Books, 2004.

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Conaty, Gerry. The Reindeer Herders of the MacKenzie Delta. Key Porter Books, 2003.

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Book chapters on the topic "Delta inulin"

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McPherson, Clifton, Richard Chubet, Kathy Holtz, et al. "Development of a SARS Coronavirus Vaccine from Recombinant Spike Protein Plus Delta Inulin Adjuvant." In Vaccine Design. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3387-7_14.

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BARBOSA, R. C., R. BERNADINO FILHO, and M. N. LOPES. "Hambúrguer ovino adicionado de inulina como substituto de gordura e ingrediente prebiótico." In Ciência e Tecnologia de Alimentos: Pesquisas e Avanços - Volume 3. Agron Food Academy, 2022. http://dx.doi.org/10.53934/9786599539695-27.

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A carne ovina é uma matéria-prima de alto valor nutricional, baixa concentração de gordura saturada, lipídeos e teor proteico acima de 20%. Desta forma o beneficiamento desta matéria-prima pode alavancar o consumo, através da produção de um derivado como é o caso do hambúrguer, foco desta pesquisa. Este trabalho teve como objetivo elaborar hambúrgueres de carne ovina e avaliar a viabilidade da adição de inulina como substituto parcial e total de gordura na qualidade microbiológica e física do produto. Foram desenvolvidas três formulações: HOG com 10% de gordura, HOIG com 5% de gordura e 5% de
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"Results from Lake Studies in Inuvik: Upland and Delta Lakes." In Electrical Phenomena During Freezing of Water and Soils. American Society of Civil Engineers, 2023. http://dx.doi.org/10.1061/9780784484487.ch15.

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