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Journal articles on the topic 'Dementia patients'

Author: Grafiati

Published: 4 June 2021

Last updated: 20 February 2023

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1

Mohr, E., P. Brouwers, J. J. Claus, S. E. Purdon, M. Gagnon, and T. N. Chase. "Differential Classification of Dementia." Behavioural Neurology 8, no. 1 (1995): 23–30. http://dx.doi.org/10.1155/1995/391254.

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In the absence of biological markers, dementia classification remains complex both in terms of characterization as well as early detection of the presence or absence of dementing symptoms, particularly in diseases with possible secondary dementia. An empirical, statistical approach using neuropsychological measures was therefore developed to distinguish demented from non-demented patients and to identify differential patterns of cognitive dysfunction in neurodegenerative disease. Age-scaled neurobehavioral test results (Wechsler Adult Intelligence Scale—Revised and Wechsler Memory Scale) from

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2

Zanni, Guido, and Jeannette Wick. "Differentiating Dementias in Long-Term Care Patients." Consultant Pharmacist 22, no. 1 (October 1, 2007): 14–28. http://dx.doi.org/10.4140/tcp.n.2007.14.

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Many long-term care residents are diagnosed with dementia, but dementia appears in many forms. Alzheimer's disease, the most common, is typified by a slow onset and relentless progression to complete incapacitation. Vascular dementia usually appears somewhat abruptly, is associated with vascular comorbidities, and has an unpredictable progression pattern. Lewy body dementia shares features of both Alzheimer's and Parkinson's disease; its hallmarks include fluctuating cognitive performance, visual hallucinations, and extrapyramidal motor symptoms. Frontotemporal dementias are associated less wi

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3

Mohr, Erich, Denise Walker, Christopher Randolph, Margaret Sampson, and Tilak Mendis. "Utility of Clinical Trial Batteries in the Measurement of Alzheimer's and Huntington's Dementia." International Psychogeriatrics 8, no. 3 (September 1996): 397–411. http://dx.doi.org/10.1017/s1041610296002761.

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Tests used as outcome measures in clinical trials of antidementia agents are not typically employed as part of diagnostic evaluations, and little information exists as to the sensitivity of these tests in terms of either differentiating demented patients from normal individuals or in distinguishing dementias of various types and etiologies. Sensitivity to mild dementia and sensitivity to impairment of various neuropsychological domains are, however, prerequisites for valid use of an instrument as an outcome measure in this context. The present study was undertaken to directly compare six diffe

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4

Langhorne, Samuel. "Patients with dementia and depression-complexity." Psychology and Mental Health Care 2, no. 3 (July 6, 2018): 01–03. http://dx.doi.org/10.31579/2637-8892/030.

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For a long time researchers and clinicians have been trying to clarify the possible existing relationships between Alzheimer’s disease and the depression in the elderly. This article tries to take stock of these complex links. It seems that often depression is clinically confused with apathy.

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5

Cummings, Jeffrey L. "Neuropsychiatric Assessment and Intervention in Alzheimer's Disease." International Psychogeriatrics 8, S1 (October 1996): 25–30. http://dx.doi.org/10.1017/s1041610296003043.

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Dementia is a major public health problem in the United States and the world, requiring the expenditure of enormous economic and human resources. Dementia is common in the elderly, and, as the size of the aged population increases, the number of dementia victims will rise. Many dementias are fatal, producing the gradual erosion of intellectual abilities and eventual death of the patient. Demands made on family members and caregivers of dementia patients are extraordinary and often result in their emotional and financial exhaustion. Although basic science efforts are devoted to finding a cure f

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6

Cipriani, Gabriele, Sabrina Danti, Lucia Picchi, Angelo Nuti, and Mario Di Fiorino. "Daily functioning and dementia." Dementia & Neuropsychologia 14, no. 2 (June 2020): 93–102. http://dx.doi.org/10.1590/1980-57642020dn14-020001.

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Abstract. Dementia is characterized by a decline in memory, language, problem-solving and in other cognitive domains that affect a person’s ability to perform everyday activities and social functioning. It is consistently agreed that cognitive impairment is an important risk factor for developing functional disabilities in patients with dementia. Functional status can be conceptualized as the ability to perform self-care, self- maintenance and physical activity. A person with dementia usually requires help with more complex tasks, such as managing bills and finances, or simply maintaining a ho

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7

Eloniemi-Sulkava, Ulla, Irma-Leena Notkola, Kaija Hämäläinen, Terhi Rahkonen, Petteri Viramo, Maija Hentinen, Sirkka-Liisa Kivelä, and Raimo Sulkava. "Spouse Caregivers' Perceptions of Influence of Dementia on Marriage." International Psychogeriatrics 14, no. 1 (March 2002): 47–58. http://dx.doi.org/10.1017/s104161020200827x.

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Objectives: To investigate what kind of changes spouse caregivers of demented patients experience after the onset of dementia (a) in the general atmosphere, happiness, and relations of marriage and (b) in the sexual side of marriage. Design: Semistructured telephone interviews of spouse caregivers of demented patients. Setting: Community-living demented patients and their spouse caregivers in eastern Finland. Participants: The spouse caregivers of 42 demented patients recruited from a previous intervention study. Measures: The questionnaire covered different areas of marriage from the time bef

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8

Hershey, Linda A., David F. Jaffe, P. Gregg Greenough, and Shu-Li An Yang. "Validation of Cognitive and Functional Assessment Instruments in Vascular Dementia." International Journal of Psychiatry in Medicine 17, no. 2 (June 1988): 183–92. http://dx.doi.org/10.2190/af5l-ah89-llv7-xen4.

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Vascular dementia is a common and potentially reversible type of dementing illness. Simple, yet valid, assessment instruments are needed to quantitate the severity of cognitive and functional impairment in vascular dementia patients seen in consultation or studied in therapeutic trials. Among sixty-three patients with known ischemic cerebrovascular disease, we found thirteen who satisfied research criteria for vascular dementia, nineteen who were “borderline” and thirty-one who were not demented. We administered the Cognitive Capacity Screening Examination and the Functional Activities Questio

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9

Torian, Lucia, Emily Davidson, George Fulop, Laura Sell, and Howard Fillit. "The Effect of Dementia on Acute Care in a Geriatric Medical Unit." International Psychogeriatrics 4, no. 2 (September 1992): 231–39. http://dx.doi.org/10.1017/s1041610292001066.

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Treatment of dementia costs billions of dollars in long-term care and community services every year. Dementia also burdens the acute care system and may contribute to financial problems for hospitals serving large numbers of demented elderly. In a specialized geriatric medical unit devoted to acute care of the frail elderly, Alzheimer's disease and vascular and mixed dementias afflicted 63% of inpatients and were associated with excess consumption of nursing resources, complications of treatment, nosocomial infections, lengthy hospitalizations, and financial losses to the hospital. Due in part

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10

Brouwers, P., E. Mohr, K. Hildebrand, M. Hendricks, J. J. Claus, I. S. Baron, M. Young, and P. Pierce. "A Novel Approach to the Determination and Characterization of HIV Dementia." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 23, no. 2 (May 1996): 104–9. http://dx.doi.org/10.1017/s0317167100038804.

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ABSTRACT:Background: Neuropsychological studies of the pattern and extent of cognitive impairment in HIV-infected patients have mostly used deviations from control values and/or cut-off scores as criteria for classification of dementia. There is, however, no agreement as to how to define impairment, and classification is imprecise. Method: The current study used a dementia classification matrix, developed with a step-wise linear discriminant analysis of neuropsychological data from patients with primary neurodegenerative dementias, to classify symptomatic HIV patients as demented or non-dement

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11

Jelastopulu, Eleni, Evangelia Giourou, Konstantinos Argyropoulos, Eleftheria Kariori, Eleftherios Moratis, Angeliki Mestousi, and John Kyriopoulos. "Demographic and Clinical Characteristics of Patients with Dementia in Greece." Advances in Psychiatry 2014 (November 17, 2014): 1–7. http://dx.doi.org/10.1155/2014/636151.

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Introduction. Dementia’s prevalence increases due to population aging. The purpose of this study was to determine the demographic profile of Greek patients with dementia and the differences in management between the urban and rural population. Methods. A cross sectional study was carried out including 161 randomly selected specialists from different regions in Greece who filled in a structured questionnaire relating to patients with dementia, regarding various sociodemographic and clinical characteristics. Results. A total of 4580 patients (52% males) with dementia were recorded. Mean age was

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12

Custodio, Nilton, David Lira, Eder Herrera-Perez, Liza Nuñez del Prado, José Parodi, Erik Guevara-Silva, Sheila Castro-Suarez, and Rosa Montesinos. "Cost-of-illness study in a retrospective cohort of patients with dementia in Lima, Peru." Dementia & Neuropsychologia 9, no. 1 (March 2015): 32–41. http://dx.doi.org/10.1590/s1980-57642015dn91000006.

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Dementia is a major cause of dependency and disability among older persons, and imposes huge economic burdens. Only a few cost-of-illness studies for dementia have been carried out in middle and low-income countries. OBJECTIVE: The aim of this study was to analyze costs of dementia in demented patients of a private clinic in Lima, Peru. Methods. We performed a retrospective, cohort, 3-month study by extracting information from medical records of demented patients to assess the use of both healthcare and non-healthcare resources. The total costs of the disease were broken down into direct (medi

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Bello, Valeska Maria Eboli, and Rodrigo Rizek Schultz. "Prevalence of treatable and reversible dementias: A study in a dementia outpatient clinic." Dementia & Neuropsychologia 5, no. 1 (March 2011): 44–47. http://dx.doi.org/10.1590/s1980-57642011dn05010008.

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Abstract Dementia is a syndrome characterized by the development of multiple cognitive deficits and behavioral changes that leads to impairment of functional activities. There are primary degenerative, progressive and irreversible dementias, and other dementias resulting from a progressive but potentially reversible dementia of secondary origin. Objective: To assess the prevalence of cases with a diagnosis of potentially reversible dementia at a Behavioral Neurology Outpatient Unit. Methods: A retrospective study based on a review of 340 medical records of patients seen from 1999 to 2009 was c

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Lyu, Jiyoung, and Yeon Ok Lim. "Exploring Direct Care Workers' Experiences with Dementia Patients." Crisis and Emergency Management: Theory and Praxis 12, no. 4 (April 30, 2022): 19–26. http://dx.doi.org/10.14251/jscm.2022.4.19.

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This study aimed to elicit and understand the experience of direct care workers involved with dementia patients. Conventional content analysis was used in this study. Fifteen direct care workers, associated with either nursing homes or elderly daycare centers in Korea, were recruited. Semi-structured, in-depth interviews were conducted to collect data. All interviews were recorded using digital devices, transcribed, and qualitatively analyzed. Four key areas were identified: (1) confusion due to ignorance and inexperience; (2) difficulties due to personal, familial, and environmental obstacles

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Leroi, I., C. Steele, and C. G. Lyketsos. "The care of patients with dementia." Reviews in Clinical Gerontology 9, no. 3 (August 1999): 235–55. http://dx.doi.org/10.1017/s0959259899009351.

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The dementias which affect the elderly are chronic diseases with protracted courses, substantial morbidity, complicated presentations and serious effects on families and caregivers. The care of a patient with dementia is therefore complex, requiring a rational model of treatment including careful multidisciplinary evaluation, a treatment plan, and ongoing reassessment. The aim of this article is to provide a framework for any clinician involved in the management of patients with dementia. Dementia has been thought of as untreatable by some health professionals: however, in many ways it can be

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Lautenschlager, Nicola T., and Ralph N. Martins. "Common versus uncommon causes of dementia." International Psychogeriatrics 17, s1 (September 2005): S27—S34. http://dx.doi.org/10.1017/s1041610205002000.

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When patients present with a dementia syndrome at a young age, the experienced clinician will automatically include uncommon dementias in the diagnostic considerations, as familial uncommon dementias due to genetic mutations frequently present as early-onset dementias. This paper highlights why uncommon dementias due to genetic mutations, although marginal in terms of prevalence numbers in the total population, are of significance in the quest to unravel the underlying cause of common dementias such as Alzheimer's disease (AD), dementia with Lewy bodies (DLB), frontotemporal dementias (FTD) an

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17

Jones, R. W. "Dementia." Scottish Medical Journal 42, no. 5 (October 1997): 151–53. http://dx.doi.org/10.1177/003693309704200512.

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Dementia in general and Alzheimer's disease in particular represent conditions where new findings are being made rapidly. Some of these developments will lead to progress of increasing clinical value to patients and their carers. This review will begin with some general points about dementia before considering current developments in Alzheimer's disease and other specific dementias in more detail.

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18

Hogan, David B., Daniel E. Thierer, Erika M. Ebly, and Irma M. Parhad. "Progression and Outcome of Patients in a Canadian Dementia Clinic." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 21, no. 4 (November 1994): 331–38. http://dx.doi.org/10.1017/s0317167100040919.

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Abstract:Five hundred and fifty-three patients were referred to a Canadian dementia clinic for standardized evaluation. The majority (83.5%) had a dementia with Alzheimer’s disease (AD) accounting for 89% of dementias. Patients with probable AD who were followed for five years had variable rates of progression, increased mortality (37.1%, 2.5 times the expected rate) and a high rate of institutionalization (79%). Simple demographic (age) and social factors (marital status) were strong predictors for institutionalization. It was extremely difficult at presentation to predict the rate of progres

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19

Davis, Laura, Zarina Karim, and Tom Dening. "Diagnostic, management and nursing challenges of less common dementias: Frontotemporal dementia, alcohol-related dementia, HIV dementia and prion diseases." British Journal of Neuroscience Nursing 18, no. 1 (February 2, 2022): 26–37. http://dx.doi.org/10.12968/bjnn.2022.18.1.26.

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Background: Most cases of dementia are due to Alzheimer's disease or vascular dementia, but attention on these disorders means that other important causes of dementia may be relatively neglected. About 10–15% of people with dementia have other diagnoses, and there are numerous causes of the less common types of dementia. Aims: This paper provides information about the causes, symptoms, diagnosis and nursing management of some of the different types of less common dementias, with the aim of helping nurses to provide better care to patients and families affected. Methods: This is one of two conn

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20

Elmståhl, Sölve, Ingegerd Stenberg, Lena Annerstedt, and Bengt Ingvad. "Behavioral Disturbances and Pharmacological Treatment of Patients With Dementia in Family Caregiving: A 2-Year Follow-Up." International Psychogeriatrics 10, no. 3 (September 1998): 239–52. http://dx.doi.org/10.1017/s1041610298005353.

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Behavioral disturbances are common in dementia. Polypharmacy due to progression of disease and fluctuation of symptoms among patients might increase risk of overtreatment and/or undertreatment. Drug prescription habits were studied in relationship to symptoms of dementia after relocation of patients to group-living care units (GC). Seventy-six demented patients (mean age 81 years) were assessed before, 12 months after, and 24 months after relocation to GC. Vascular dementia was found in 47%, Alzheimer's dementia in 46%, and other dementias in 7%. Medications, regular or as required, were recor

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Zupanic, Eva, Mia von Euler, Bengt Winblad, Hong Xu, Juraj Secnik, Milica Gregoric Kramberger, Dorota Religa, Bo Norrving, and Sara Garcia-Ptacek. "Mortality After Ischemic Stroke in Patients with Alzheimer’s Disease Dementia and Other Dementia Disorders." Journal of Alzheimer's Disease 81, no. 3 (June 1, 2021): 1253–61. http://dx.doi.org/10.3233/jad-201459.

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Background: Stroke and dementia are interrelated diseases and risk for both increases with age. Even though stroke incidence and age-standardized death rates have decreased due to prevention of stroke risk factors, increased utilization of reperfusion therapies, and other changes in healthcare, the absolute numbers are increasing due to population growth and aging. Objective: To analyze predictors of death after stroke in patients with dementia and investigate possible time and treatment trends. Methods: A national longitudinal cohort study 2007–2017 using Swedish national registries. We compa

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Sunderland, Trey, and Marcia Minichiello. "Dementia Mood Assessment Scale." International Psychogeriatrics 8, S3 (May 1997): 329–31. http://dx.doi.org/10.1017/s1041610297003578.

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The behavioral symptoms seen in patients with dementia are diverse, ranging from agitation to hallucinations and paranoid delusions. Many patients with dementia have affective disturbances, including depressed mood. To provide a means of assessing the severity of depression and mood changes in demented patients, the authors and colleagues at the National Institute of Mental Health developed the Dementia Mood Assessment Scale.

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Verhey, Frans R. J., and Pieter Jelle Visser. "Phenomenology of Depression in Dementia." International Psychogeriatrics 12, S1 (July 2000): 129–34. http://dx.doi.org/10.1017/s1041610200006906.

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Dementia and depression are the two most prevalent psychiatric disorders in the elderly. Although dementia has traditionally been viewed as a disorder of cognition, and depression as a disorder of mood, this simple classification has recently been questioned, and the complex interrelationship between depression and dementia is being elucidated (Emery & Oxman, 1992; Raskind, 1998). Patients with depression may show cognitive deficits, simulating dementia (Berrios, 1989), and patients with dementing disorders may show symptoms of depression (Allen & Burns, 1995; Burns, 1991). In addition

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Fu, Catherina, Dennis J. Chute, Emad S. Farag, Justine Garakian, Jeffrey L. Cummings, and Harry V. Vinters. "Comorbidity in Dementia." Archives of Pathology & Laboratory Medicine 128, no. 1 (January 1, 2004): 32–38. http://dx.doi.org/10.5858/2004-128-32-cid.

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Abstract Context.—There is a paucity of accurate postmortem data pertinent to comorbid medical conditions in patients with dementia, including Alzheimer disease. Objectives.—The purposes of this study were (a) to examine general autopsy findings in patients with a dementia syndrome and (b) to establish patterns of central nervous system comorbidity in these patients. Design.—Review of autopsy reports and selected case material from 202 demented patients who had “brain-only” autopsies during a 17-year period (1984–2000) and from 52 demented patients who had general autopsies during a 6-year per

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Wright, Christine E., and Paul L. Furlong. "Visual Evoked Potentials in Elderly Patients with Primary or Multi-Infarct Dementia." British Journal of Psychiatry 152, no. 5 (May 1988): 679–82. http://dx.doi.org/10.1192/bjp.152.5.679.

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Flash and pattern-reversal visual evoked potentials (VEP) were recorded in 35 elderly patients with dementia, and 19 controls of equivalent age. Dementia produced a slowing of the major positive (P2) component of the flash VEP but did not affect the latency of the flash P1 component or the P100 pattern-reversal component. This unusual type of abnormality was found in both primary and multi-infarct types of dementia, and has previously been found in primary presenile dementia. The results show that the VEP can be used for the diagnosis of multi-infarct, and primary presenile and senile dementia

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STERN, YAAKOV, MING-XIN TANG, DIANE M. JACOBS, MARY SANO, KAREN MARDER, KAREN BELL, GEORGE DOONEIEF, PETER SCHOFIELD, and LUCIEN CÔTÉ. "Prospective comparative study of the evolution of probable Alzheimer's disease and Parkinson's disease dementia." Journal of the International Neuropsychological Society 4, no. 3 (May 1998): 279–84. http://dx.doi.org/10.1017/s1355617798002793.

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No previous comparison of test performance in probable Alzheimer's disease (pAD) and Parkinson's disease (PD) dementia has provided information about potential differences in the dementing process. This study compared the evolution of cognitive changes associated with these dementias. Generalized estimating equations (GEE) applied to regression analyses with repeated measures were used to evaluate cognitive changes over 1 to 3 years prior to the point when dementia was diagnosed in 40 matched pairs of patients with incident pAD and PD dementia. Both groups' performance declined on the Short Bl

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Goldberg, Terry E., Joel E. Kleinman, David G. Daniel, Michael S. Myslobodsky, John D. Ragland, and Daniel R. Weinberger. "Dementia Praecox Revisited." British Journal of Psychiatry 153, no. 2 (August 1988): 187–90. http://dx.doi.org/10.1192/bjp.153.2.187.

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Thirty-nine patients with DSM–III diagnoses of schizophrenia were examined for age disorientation, an inability to produce one's correct chronological age upon request. Six patients were age-disoriented and demented (as defined by Mini-Mental State evaluation), while two patients had delusions concerning their age, but were not demented. Age-disoriented, demented patients had very large cerebral ventricles and very low Mini-Mental State scores. This group differed on the cognitive and neuroanatomic variables from other demented, but not age-disoriented, patients, as well as from non-demented p

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Sánchez Iglesias, Ana, José Antonio Del Barrio, Josefa González-Santos, Florencio Vicente Castro, Jerónimo González, David Padilla Góngora, Alfredo Jiménez, et al. "MINDFULNESS Y REHABILITACIÓN NEUROCOGNITIVA." International Journal of Developmental and Educational Psychology. Revista INFAD de Psicología. 1, no. 1 (October 2, 2017): 21. http://dx.doi.org/10.17060/ijodaep.2017.n1.v1.895.

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Abstract.MINDFULNESS AND NEUROCOGNITIVE REHABILITATION.Nowadays approximately fifty million persons are suffering from dementia throughout the world according to the latest statistics of the European Commission (2016). Moreover, every year new 7.7 million instances of this disease are detected. At this moment, Alzheimer’s disease would be the most common mental disorder in terms of world population health, in other words, this disease can signify 70% of all dementia. Even now pharmacological treatments are ineffective. Consequently, utilization of non pharmacological therapies is opening a wid

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Kim, Seon-Jip, Sang Min Park, Hyun-Jae Cho, and Ji Woon Park. "Primary headaches increase the risk of dementias: An 8-year nationwide cohort study." PLOS ONE 17, no. 8 (August 18, 2022): e0273220. http://dx.doi.org/10.1371/journal.pone.0273220.

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Background Headache, a highly prevalent neurological disorder, has consistently been linked with an elevated risk of dementia. However, most studies are focused on the relationship with migraine in limited age groups. Therefore, the objective of this research was to look at the link between various type of headaches and dementias based on longitudinal population-based data. Methods and results Participants diagnosed with headache from 2002 to 2005 were selected and major covariates were collected. The diagnoses of Alzheimer’s disease, vascular dementia, and other dementias were observed from 2

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Sá Esteves, P., D. Loureiro, E. Albuquerque, F. Vieira, L. Lagarto, S. Neves, and J. Cerejeira. "Dementia in acutely-ill medical elderly patients." European Psychiatry 33, S1 (March 2016): S190. http://dx.doi.org/10.1016/j.eurpsy.2016.01.429.

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IntroductionDementia is one of the leading causes of disability and burden in Western countries. In Portugal, there is a lack of data regarding dementia prevalence in hospitalized elderly patients and factors associated with in-hospital adverse outcomes of these patients.ObjectivesDetermine dementia prevalence in acutely-ill medical hospitalized elderly patients and its impact in health outcomes.MethodsAll male patients (> 65 years) admitted to a medical ward (> 48 h) between 1.03.2015 to 31.08.2015 were included in the study. Patients were excluded if unable to be assessed due to sensor

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Gan, Jinghuan, Meng Wang, Shuai Liu, Zhichao Chen, Xiao-Dan Wang, and Yong Ji. "Effect of Multiple Medicines on Dementia Initial Treatment: Experience and Thinking." American Journal of Alzheimer's Disease & Other Dementias® 36 (January 2021): 153331752110531. http://dx.doi.org/10.1177/15333175211053134.

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Little is known about multiple medicines and initial therapy among people with dementia. To examine the effect of multiple medicines on the initiation of anti-dementia therapy in patients diagnosed with cognitive impairment (CI), a retrospective study with 2742 CI patients was conducted based on the outpatients’ medical records. The dementias receiving 1–2 drugs were more likely to be prescribed with anti-dementia (one drug: OR = 1.877; two drugs: OR = 1.770) and psychotropic (one drug: OR = 1.980) treatment, whereas had lower chances of receiving psychotropic medication with the combinations

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Johansson, Alf, and Lars Gustafson. "Psychiatric Symptoms in Patients With Dementia Treated in a Psychogeriatric Day Hospital." International Psychogeriatrics 8, no. 4 (December 1996): 645–58. http://dx.doi.org/10.1017/s1041610296002955.

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Sixty-five consecutive patients with dementia, treated at a psychogeriatric day hospital, were studied regarding prevalence of psychiatric symptoms. The clinical diagnoses were dementia of the Alzheimer type (n = 19), vascular dementia (n = 27), mixed Alzheimer's disease and vascular dementia (n = 13), vascular dementia of frontal type (n = 2), and other diseases (n = 4). Mean age at referral was 75.6 ± 6.6 years and the average treatment time was 21 ± 14 months. About 90% of the patients showed one or several significant psychiatric symptoms during the course of dementia. Most common were del

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Hasna Imami, Nabilah, Yudha Haryono, Anggraini Dwi Sensusiati, Muhammad Hamdan, and Hanik Badriyah Hidayati. "DEMENTIA IN DR. SOETOMO GENERAL HOSPITAL SURABAYA: A SYNTHETIC REVIEW OF ITS CHARACTERISTICS." MNJ (Malang Neurology Journal) 7, no. 1 (January 1, 2021): 12–16. http://dx.doi.org/10.21776//ub.mnj.2021.007.01.3.

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Background: Dementia is a clinical syndrome characterized by progressive loss of cognitive function in elderly people interferes the ability to function independently. The number of elderly patients increased so fast in worldwide. The prevalence of dementia rapidly increases due to increasing of population. Aging demographic transition is proceeding rapidly especially in China, India, and Latin America, where dementia is rapidly becoming the major public health problem. Demographic data of elderly patients of dementia in Indonesia is still a little. Dementia’s research data in Indonesia were o

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Velayudhan, Latha, Seung-Ho Ryu, Malgorzata Raczek, Michael Philpot, James Lindesay, Matthew Critchfield, and Gill Livingston. "Review of brief cognitive tests for patients with suspected dementia." International Psychogeriatrics 26, no. 8 (March 31, 2014): 1247–62. http://dx.doi.org/10.1017/s1041610214000416.

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ABSTRACTBackground:As the population ages, it is increasingly important to use effective short cognitive tests for suspected dementia. We aimed to review systematically brief cognitive tests for suspected dementia and report on their validation in different settings, to help clinicians choose rapid and appropriate tests.Methods:Electronic search for face-to-face sensitive and specific cognitive tests for people with suspected dementia, taking ≤ 20 minutes, providing quantitative psychometric data.Results:22 tests fitted criteria. Mini-Mental State Examination (MMSE) and Hopkins Verbal Learning

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Camargos, Einstein Francisco, Marcela Basso Pandolfi, Marco Polo Dias Freitas, Juliana Lima Quintas, Juliana de Oliveira Lima, Leandra Camapum Miranda, Luciano Wanderley Pimentel, and Patricia Medeiros-Souza. "Trazodone for the treatment of sleep disorders in dementia: an open-label, observational and review study." Arquivos de Neuro-Psiquiatria 69, no. 1 (February 2011): 44–49. http://dx.doi.org/10.1590/s0004-282x2011000100010.

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Sleep disorders (SD) in patients with dementia are very common in clinical practice. The use of antidepressants with hypnotic actions, such as trazodone, plays an important role in these cases. The aim of this study is to present a profile of the use of trazodone in demented patients with SD, as well as a review of trazodone hydrochloride in SD. We evaluated 178 elderly patients with Alzheimer's disease and other dementias, clinically presenting SD and treated with hypnosedative medications. In the one-year period comprising the study, 68 (38.2%) of the 178 had sleep disorders. Most patients (

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Khalil, Mohammad Ibrahim, Narayan Chandra Kundu, Serajoom Munira, Mahmood-uz Jahan, and Md Ridwanur Rahman. "Predictors of Parkinson’s disease Dementia in a Sample of Bangladeshi Patients." Bangladesh Medical Research Council Bulletin 47, no. 2 (May 17, 2022): 192–98. http://dx.doi.org/10.3329/bmrcb.v47i2.57779.

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Background: Parkinson’s disease dementia (PDD) is a common consequence during the course of the disease. It deeply influences patients’ prognosis, quality of life, caregiver burden and economic strain. However, effective treatment for PDD is currently unclear. Clinical and demographic predictors for this comorbidity are not well studied. Objectives: To investigate putative risk factors for the development of dementia in patients with Parkinson’s disease (PD) attending a tertiary care and teaching hospital in Bangladesh. Methods: One hundred thirty-one consecutive PD cases were enrolled in this

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Rana, Md Masud, Imran Sarker, Md Shahadat Hossain, Md Rezaul Karim Khan, Md Rafiqul Islam, Abu Naser Rizvi, Md Ahsan Habib, Md Nazrul Islam, Anis Ahmed, and Md Bahadur Ali Miah. "Etiological Pattern of Dementia in Patients Attending Dementia Clinic in a Referal Hospital." Bangladesh Journal of Neuroscience 30, no. 2 (July 31, 2014): 77–83. http://dx.doi.org/10.3329/bjn.v30i2.57390.

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Background and objectives: Dementia is characterized by loss of or decline in memory and other cognitive abilities and reduces the lifespan of affected people. The number of people with Alzheimer’s Disease and other dementias is increasing every year because of the steady growth in the older population and stable increment in life expectancy and it is expected to increase two-fold by 2030 and three-fold by 2050.In addition to Alzheimer’s disease there are so many reversible and irreversible causes of dementia. This study was aimed to explore the different etiological factors related to dementi

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Hamdy, R. C., A. Kinser, A. Depelteau, T. Kendall-Wilson, J. V. Lewis, and K. Whalen. "Patients with Dementia Are Easily Distracted." Gerontology and Geriatric Medicine 3 (January 1, 2017): 233372141773593. http://dx.doi.org/10.1177/2333721417735938.

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Mild cognitive impairment (MCI) is the middle ground between normal, age-appropriate memory impairment, and dementia. Whereas patients with MCI are able to cope with the memory deficit, those with dementia are not: Their memory impairment and other cognitive deficits are of sufficient magnitude to interfere with the patients’ ability to cope independently with daily activities. In both MCI and dementia, there is evidence of declining cognitive functions from a previously higher level of functioning. In both the conditions, there is also an evidence of dysfunction in one or more cognitive domai

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Starkstein, S. E., S. Vázquez, G. Petracca, L. Sabe, M. Merello, and R. Leiguarda. "SPECT Findings in Alzheimer’s Disease and Parkinson’s Disease with Dementia." Behavioural Neurology 10, no. 4 (1997): 121–27. http://dx.doi.org/10.1155/1997/379683.

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We examined, with single photon emission tomography (SPECT) and (99mTc)-HMPAO, 18 patients with idiopathic Parkinson's disease and no dementia (PD), 12 patients with PD and dementia, 24 patients with probable Alzheimer's disease (AD), and 14 controls. While the three patient groups showed significantly lower perfusion in frontal inferior and temporal inferior areas as compared to controls, both demented groups showed significantly more severe bilateral hypoperfusion in superior frontal, superior temporal and parietal areas as compared to non-demented PD patients and controls. On the other hand

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Miller, T. Bryce. "Helping dementia patients." Canadian Pharmacists Journal / Revue des Pharmaciens du Canada 149, no. 4 (July 2016): 194. http://dx.doi.org/10.1177/1715163516651813.

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Potashkin, Judith A., Virginie Bottero, Jose A. Santiago, and James P. Quinn. "Bioinformatic Analysis Reveals Phosphodiesterase 4D-Interacting Protein as a Key Frontal Cortex Dementia Switch Gene." International Journal of Molecular Sciences 21, no. 11 (May 27, 2020): 3787. http://dx.doi.org/10.3390/ijms21113787.

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The mechanisms that initiate dementia are poorly understood and there are currently no treatments that can slow their progression. The identification of key genes and molecular pathways that may trigger dementia should help reveal potential therapeutic reagents. In this study, SWItch Miner software was used to identify phosphodiesterase 4D-interacting protein as a key factor that may lead to the development of Alzheimer’s disease, vascular dementia, and frontotemporal dementia. Inflammation, PI3K-AKT, and ubiquitin-mediated proteolysis were identified as the main pathways that are dysregulated

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Snowden, Julie S., David Neary, and David M. A. Mann. "Frontotemporal dementia." British Journal of Psychiatry 180, no. 2 (February 2002): 140–43. http://dx.doi.org/10.1192/bjp.180.2.140.

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BackgroundFrontotemporal dementia accounts for up to 20% of cases of dementia in the presenium, yet remains poorly recognised. Diagnostic criteria have been devised to aid clinical diagnosis.AimsTo provide an overview of clinical and pathological characteristics of frontotemporal dementia and its nosological status.MethodsThe review summarises consensus diagnostic criteria for frontotemporal dementia and draws on the authors'clinical experience of 300 frontotemporal dementia cases, and pathological experience of 50 autopsied cases.ResultsFrontotemporal dementia is characterised by pronounced c

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Tan, Lynnette Pei Lin, Nathan Herrmann, Brian J. Mainland, and Kenneth Shulman. "Can clock drawing differentiate Alzheimer's disease from other dementias?" International Psychogeriatrics 27, no. 10 (July 3, 2015): 1649–60. http://dx.doi.org/10.1017/s1041610215000939.

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ABSTRACTBackground:Studies have shown the clock-drawing test (CDT) to be a useful screening test that differentiates between normal, elderly populations, and those diagnosed with dementia. However, the results of studies which have looked at the utility of the CDT to help differentiate Alzheimer's disease (AD) from other dementias have been conflicting. The purpose of this study was to explore the utility of the CDT in discriminating between patients with AD and other types of dementia.Methods:A review was conducted using MEDLINE, PsycINFO, and Embase. Search terms included clock drawing or CL

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Hasegawa, N., M. Hashimoto, S. Yuuki, K. Honda, Y. Yatabe, K. Araki, and M. Ikeda. "Prevalence of delirium among outpatients with dementia." International Psychogeriatrics 25, no. 11 (July 22, 2013): 1877–83. http://dx.doi.org/10.1017/s1041610213001191.

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ABSTRACTBackground:Delirium and dementia are highly interrelated. However, few comprehensive epidemiological studies have examined this altered state of consciousness superimposed on dementia. We investigated the frequency of delirium in patients with dementia, its prevalence in patients with each dementia type, and its association with cerebrovascular disease (CVD) in patients with neurodegenerative dementias.Methods:We studied 261 consecutive outpatients in the memory clinic of a psychiatric hospital between April 2010 and September 2011. All patients underwent routine laboratory tests and c

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Camicioli, Richard, and Nancy Fisher. "Progress in Clinical Neurosciences: Parkinson's Disease with Dementia and Dementia with Lewy Bodies." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 31, no. 1 (February 2004): 7–21. http://dx.doi.org/10.1017/s0317167100002791.

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Dementia occurs in up to 30% of people with Parkinson's disease and is a major cause of disability. Pathologically, Parkinson's dementia, where dementia follows the onset of parkinsonism by at least one year, overlaps with dementia with Lewy bodies. We review the functional impact, definitions, neuropsychology, epidemiology and pathophysiology of Parkinson's dementia, dementia with Lewy bodies and their overlap. Associated psychiatric and imaging findings are also considered. Lastly, current and emerging approaches to assessment and treatment in patients with these Lewy body associated dementi

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Rockwood, Kenneth. "Mixed Dementia: Alzheimer's and Cerebrovascular Disease." International Psychogeriatrics 15, S1 (July 2003): 39–46. http://dx.doi.org/10.1017/s1041610203008949.

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“Mixed dementia” is traditionally defined as Alzheimer's disease with cerebrovascular disease (CVD). Because the risks of both neurodegenerative dementias and cerebrovascular disease increase with age, the mixed dementias are likely the most common. In practice, patients with mixed dementia are diagnosed by one of two routes: Either they have evidence of a neurodegenerative dementia and CVD at the outset, or, they have a classical neurodegenerative presentation but are found to have ischemic lesions by neuroimaging. These facts have implications for the development of evidence-based diagnostic

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Godinho, Cláudia, Iulek Gorczevski, Andréa Heisler, Maria Otília Cerveira, and Márcia Lorena Chaves. "Clinical and demographic characteristics of elderly patients with dementia assisted at an outpatient clinic in Southern Brazil." Dementia & Neuropsychologia 4, no. 1 (March 2010): 42–46. http://dx.doi.org/10.1590/s1980-57642010dn40100007.

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Abstract The aging of the population is a worldwide phenomenon, where 60% of elders live in developing areas of the world such as Brazil, regions in which few studies have been carried out. Objectives: The goal of this study was to evaluate the clinical and demographic profile of patients with dementing disorders seen at a specialized outpatient clinic in South Brazil. Methods: A sample of 105 demented patients seen at the Dementia Outpatient Clinic from Hospital de Clínicas de Porto Alegre (HCPA), Brazil between June 2004 and June 2008. Evaluation of patients consisted of medical history, cog

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Singh, Atar, Abhay Paliwal, and V. S. Pal. "Comparative study of electroencephalography changes in dementia." International Journal of Research in Medical Sciences 7, no. 8 (July 25, 2019): 2970. http://dx.doi.org/10.18203/2320-6012.ijrms20193379.

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Background: Dementia affected about 46 million people in 2015and this number will roughly triple within the next 40 years. In 2011 Alzheimer's Disease International argue that dementia has become one of the most urgent health and social care challenges of the 21st century and its potential effect on economies around the world is attracting global attention. Predicting dementia in the early stages would be essential for better treatment before significant brain damage occurs. Current difficulty is the lack of specific biomarkers. In some previous studies electroencephalography (EEG) have shown

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Testa, H. J., J. S. Snowden, D. Neary, R. A. Shields, A. W. I. Burjan, M. C. Prescott, B. Northen, and P. Goulding. "The Use of [99mTc]-HM-PAO in the Diagnosis of Primary Degenerative Dementia." Journal of Cerebral Blood Flow & Metabolism 8, no. 1_suppl (December 1988): S123—S126. http://dx.doi.org/10.1038/jcbfm.1988.42.

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The clinical value of single photon emission computed tomography (SPECT) in the differential diagnosis of dementia due to cerebral atrophy was evaluated by comparing the pattern of distribution [99mTc]–HM-PAO in three dementing conditions. Imaging was carried out in 26 patients with suspected Alzheimer's disease, 14 with dementia of the frontal-lobe type, and 13 with progressive supranuclear palsy. Images were evaluated and reported without knowledge of clinical diagnosis with respect to regions of reduced uptake of tracer. Reduced uptake in the posterior cerebral hemispheres was characteristi

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Villa, Paola, Paolo Bosco, Raffaele Ferri, Concetta Perri, Rosanna Suriano, Barbara Costantini, Francesca Macrì, Caterina Proto, Rosa Maria Cento, and Antonio Lanzone. "Fasting and Post-methionine Homocysteine Levels in Alzheimers Disease and Vascular Dementia." International Journal for Vitamin and Nutrition Research 79, no. 3 (May 1, 2009): 166–72. http://dx.doi.org/10.1024/0300-9831.79.3.166.

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The aim of the study is to compare the basal homocysteine levels in patients with impairment of cognitive status, and in controls, to evaluate if the methionine loading test is able to identify any differences between patients with Alzheimers disease and patients with vascular dementia. We enrolled 56 subjects, 20 with Alzheimers disease, 18 with vascular dementia, and 18 normal controls. The data shown that plasma homocysteine levels both basal and post-methionine load were significantly higher in the two groups of demented patients than in the control group. No significant differences were

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