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Journal articles on the topic 'Demodex Mite'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Alper Alyanak and Ferda Bilgir. "Evaluation of Demodex mite in chronic urticaria." World Journal of Advanced Research and Reviews 22, no. 1 (2024): 866–69. http://dx.doi.org/10.30574/wjarr.2024.22.1.1178.

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Objective: Determining the possible role of Demodex mites in patients with chronic urticaria Methods: Demodex screening results in 49 patients with chronic urticaria were evaluated retrospectively. Results: The mean number of Demodex mites per 1 cm2 measured with standardized skin-surface biopsy (SSSB) was 0.89 which was at a similar level as control groups in the literature. Conclusion: Demodex mites seemed not to play a role in patients with chronic urticaria who had no facial eruptions. Patients with skin eruptions with the possible contribution of Demodex as rosacea could be investigated f

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Alper, Alyanak, and Bilgir Ferda. "Evaluation of Demodex mite in chronic urticaria." World Journal of Advanced Research and Reviews 22, no. 1 (2024): 866–69. https://doi.org/10.5281/zenodo.14210331.

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<strong>Objective</strong>: Determining the possible role of Demodex mites in patients with chronic urticaria <strong>Methods</strong>: Demodex screening results in 49 patients with chronic urticaria were evaluated retrospectively. <strong>Results</strong>: The mean number of Demodex mites per 1 cm<sup>2</sup> measured with standardized skin-surface biopsy (SSSB) was 0.89 which was at a similar level as control groups in the literature. <strong>Conclusion</strong>: Demodex mites seemed not to play a role in patients with chronic urticaria who had no facial eruptions. Patients with skin er

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3

Haddad Neta, Jamile. "External otitis and facial dermatitis associated with Demodex cati in a cat – case report." Clínica Veterinária XX, no. 118 (2015): 76–82. http://dx.doi.org/10.46958/rcv.2015.xx.n.118.p.76-82.

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Feline demodicosis is a parasitary dermatophathy that affects cats at a much lower frequency than the one observed in dogs. There are three species identified in felines: Demodex gatoi, Demodex cati and a third species unofficially called Demodex felis. Clinical signs are widely variable and seem to differ according to the individual species of mite involved. Diagnostic depends on mite identification upon microscopic examination of skin scrapings; Demodex gatoi may also be found in feces. The present article describes a case of localized feline demodicosis that occurred in the city of Foz do I

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Palanisamy, Madhumitha, and Dhaarna Wadhwa. "Demodex mite under microscopy." Cosmoderma 3 (July 28, 2023): 110. http://dx.doi.org/10.25259/csdm_120_2023.

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Hanlon, Katharine, Meredith Thomley, and Lilia Correa-Selm. "In Vivo View of a Reclining Demodex Mite in a Milia Cyst." Diagnostics 13, no. 10 (2023): 1718. http://dx.doi.org/10.3390/diagnostics13101718.

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Demodex folliculorum and Demodex brevis are commonly present on facial skin and frequently noted via Reflectance Confocal Microscopy (RCM) examination. These mites inhabit follicles and are often seen in groups of two or more, although D. brevis is usually found as a solitary mite. When observed through RCM, they are typically present as refractile, round groupings seen on a transverse image plane inside the sebaceous opening, as they are vertically oriented, and their exoskeletons refract under near-infrared light. Inflammation may occur, leading to a variety of skin disorders; nonetheless, t

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Willoughby, K. "Demodex mite in a cat." Veterinary Record 124, no. 6 (1989): 152. http://dx.doi.org/10.1136/vr.124.6.152.

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Bonnar, Elizabeth, Peter Eustace, and FrankC Powell. "Demodex mite in normal skin." Lancet 337, no. 8750 (1991): 1168. http://dx.doi.org/10.1016/0140-6736(91)92841-o.

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Lam, Nelson Siu Kei, Xin Xin Long, Robert C. Griffin, Mu-Kai Chen, and James CG Doery. "Can the tea tree oil (Australian native plant:Melaleuca alternifolia Cheel) be an alternative treatment for human demodicosis on skin?" Parasitology 145, no. 12 (2018): 1510–20. http://dx.doi.org/10.1017/s0031182018000495.

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AbstractAustralian tea tree oil (TTO) and its extract terpinen-4-ol (T4O) are found to be effective in moderating demodex-related diseases. Their possible effects are lowering the mite counts, relieving the demodex-related symptoms and modulating the immune system especially the inflammatory response. This review summarizes the topical treatments of TTO and T4O in human demodicosis, their possible mechanism of actions, side-effects and potential resistance in treating this condition. Although current treatments other than TTO and T4O are relatively effective in controlling the demodex mite pop

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Skonieczna, Dominika, Paulina Sławianowska, Roland Wesołowski, and Karolina Szewczyk-Golec. "Demodex mites – characteristics, pathogenicity, diagnostics." Diagnostyka Laboratoryjna 54, no. 1 (2018): 37–44. http://dx.doi.org/10.5604/01.3001.0013.7554.

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<I>Demodex</I> is a mite that colonise the human skin and thus can contribute to initiation of demodicosis – a disease caused in humans by two species (D. folliculorum and D. brevis). Demodicosis mostly involves eyes and facial skin, whereas it has become increasingly associated as an pathologic factor in diabetes mellitus and cancer. Demodex diagnostics is based on a simple classical microscopy. The availability of modern molecular biology techniques helps to get to know interspecies diversity of Demodex. Local treatment with mercury oxide, ointments containing metronidazole and c

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PALOPOLI, MICHAEL F., VAN TRA, KASSEY MATOIN, and PHUONG D. MAC. "Evolution of host range in the follicle mite Demodex kutzeri." Parasitology 144, no. 5 (2016): 594–600. http://dx.doi.org/10.1017/s0031182016002146.

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SUMMARYThe sequences of four mitochondrial genes were determined for Demodex mites isolated from two distantly related species within the family Cervidae, and identified morphologically as belonging to the species Demodex kutzeri. The sequences were used to test the hypothesis that Demodex are strictly host-specific, and hence cospeciate with their hosts: (1) The estimated divergence time between mites found on elk vs humans agreed closely with a previous estimate of the time that these host species last shared a common ancestor, suggesting cospeciation of mites and hosts, at least over long e

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Mavlyanova, Sh Z., A. I. Ismogilov, and Zh B. Mullakhanov. "Monitoring of the quantitative assessment of the tick Demodex folliculorum in the clinical course of rosacea." Terapevt (General Physician), no. 4 (April 20, 2025): 21–29. https://doi.org/10.33920/med-12-2504-02.

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In rosacea patients, the Demodex folliculorum was detected on the skin of the lesions in 68.1% of cases. According to the species identification, Demodex folliculorum longus was detected in 64.5%, and Demodex folliculorum brevis – in 35.4%. Taking into account the severity according to the Rosacea Diagnostic Assessment Scale, Demodex brevis was most often isolated in patients with a mild severity, and Demodex folliculorum longus – with moderate and high severity (55% and 93.5%, respectively). With increasing severity of the clinical course, the count of the Demodex folliculorum increased by 2.

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Mohebbi, Hesamoddin, Shayan Boozarjomehri Amniyeh, Parisa Mahdavi, and Ali Heydari Azar Heris. "A Case Report of Human Demodicosis in a Patient Referred to a Dermatology Clinic in Tabriz, Iran." International Journal of Medical Parasitology and Epidemiology Sciences 1, no. 1 (2020): 21–22. http://dx.doi.org/10.34172/ijmpes.2020.07.

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Background: The genus Demodex belongs to the order Prostigmata and the family Demodecidae that has several species of uncommon mites, some of which cause severe scabies in animals. There are two species of this mite that cause disease in humans, including Demodex folliculorum, which is known as hair follicle mite, and Demodex brevis. This disease is more common in women than in men. Case Presentation: The patient is a 36-year-old woman living in one of the villages of Tabriz city who referred to a dermatologist following severe itching and hyperkeratosis (abundant dandruff) of the cheeks. Then

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Chudzicka-Strugała, Izabela, Ida Judyta Mądry, Michał Malesza, et al. "Demodex Mite Infections in Ophthalmic Patients on Indonesian Islands: The ICS Humanitarian Aid Report." International Surgery 103, no. 3-4 (2018): 122–28. http://dx.doi.org/10.9738/intsurg-d-18-00031.1.

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Objective: Demodex is the most common external human parasite. It has been suggested that the Demodex infection may be associated with malnutrition, nutritional deficiencies, reduced immunity, and poor hygiene. The patients who benefitted from humanitarian aid in Indonesia, often demonstrated the abovementioned risk factors. The aim of the present report was to assess the prevalence of Demodex infestation in ophthalmic patients in Indonesian. Patients and methods: A total of 217 individuals (132 women) with ocular discomfort, who presented to the ophthalmologist in mission points in Indonesia

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Handa, Sabia, Parul Goyal, Suryaprakash Sharma, Amanjit Bal, Manpreet Singh, and Pankaj Gupta. "Upper Eyelid Nodule - An Unusual Presentation of Ocular Demodicosis." Nepalese Journal of Ophthalmology 13, no. 2 (2021): 207–10. http://dx.doi.org/10.3126/nepjoph.v13i2.27076.

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Introduction: Demodex mite is an external parasite which is implicated in various ocular conditions like anterior blepharitis, posterior blepharitis, meibomian gland dysfunction, chalazia and others. Although demodex has been shown to be a causative agent of chalazia, occurrence of a solitary inflammatory nodule due to demodex infestation has not been reported in literature. Case: Our case describes the occurrence of an upper eyelid mass in a 62-year-old female which was found to have an associated demodex infestation. Conclusion: This is the first report of demodex infestation presenting as a

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Bonnar, E., P. Eustace, and F. C. Powell. "The Demodex mite population in rosacea." Journal of the American Academy of Dermatology 28, no. 3 (1993): 443–48. http://dx.doi.org/10.1016/0190-9622(93)70065-2.

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Rather, ParvaizAnwar, and Iffat Hassan. "Human Demodex Mite: The Versatile Mite of Dermatological Importance." Indian Journal of Dermatology 59, no. 1 (2014): 60. http://dx.doi.org/10.4103/0019-5154.123498.

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Gupta, Aayush, and YugalKishor Sharma. "Human demodex mite: The versatile mite of dermatological importance." Indian Journal of Dermatology 59, no. 3 (2014): 302. http://dx.doi.org/10.4103/0019-5154.131416.

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Gholinezhad, Danial, Rozhin Bahrampour, Alireza Naghdi Bazneshin, and Arian Hamidi Nokhostin. "Diagnosis and Treatment of Demodicosis in Pet Dogs with Dermatological Lesions by Amitraz in Tabriz, Iran." International Journal of Medical Parasitology and Epidemiology Sciences 4, no. 3 (2023): 76–79. http://dx.doi.org/10.34172/ijmpes.3141.

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Introduction: Demodex is a tiny parasite (smaller than one millimeter) that can sometimes cause a skin disease called Demodicosis in dogs and cats. Demodicosis in dogs is created by three species of mites called Demodex canis, Demodex injai, and Demodex cornei. The most common mite-causing demodicosis in dogs is D. canis. This mite lives in hair roots and sometimes in sebaceous glands, where they feed on cells. Methods: This study was conducted on 200 pet dogs aged one month to 9 years referred to veterinary clinics in Tabriz, Iran, who had clinical symptoms of dermatological lesions from Nove

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Artemov, О. V., M. V. Lytvynenko, N. V. Neskoromna, et al. "Pathomorphosis of eyelid tumor pathology in demodectic infection." Inter Collegas 11, no. 1 (2024): 5–10. http://dx.doi.org/10.35339/ic.11.1.aln.

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Background. Pathological changes in the tissues of the oculo-conjunctival region caused by the activity of the Demodex mite is represented by the development of inflammatory process. On detection of the parasite on eyelashes, the presence of the Demodex mite is diagnosed in half of adult patients seeking ophthalmic care. Pathomorphological descriptions of specific patterns associated with the presence of Demodex infection are practically absent. During pathological examination, in the vast majority of cases it is almost impossible to see the parasite in the test material. There are pathomorpho

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Wijaya, Ardy, Duman Care Khrisne, and Lie Jasa. "APLIKASI MOBILE DETEKSI PENYAKIT DEMODEKOSIS PADA ANJING MENGGUNAKAN METODE CONVOLUTIONAL NEURAL NETWORK." Jurnal SPEKTRUM 8, no. 2 (2021): 138. http://dx.doi.org/10.24843/spektrum.2021.v08.i02.p16.

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Demodex is a skin disease in dogs caused by the protozoan mite Demodexfollicularumvar canis or Demodex canis. These mites are found in the hair roots and sometimesin the glands, almost the entire life cycle of this type of mite is on the skin, if it lasts for a longtime it can cause death in dogs that are infested by these lice This study aims to detectdemodicosis in dogs with a mobile application using a convolutional neural network methodwith a squeezenet architecture model with radam optimization. This application works by takingpictures directly through the cellphone camera then processing

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Barnett, Melissa, Blake Simmons, Patrick Vollmer, et al. "The impact of Demodex blepharitis on patient symptoms and daily life." Optometry and Vision Science 101, no. 3 (2024): 151–56. http://dx.doi.org/10.1097/opx.0000000000002111.

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SIGNIFICANCE Patients with Demodex blepharitis have a considerable symptomatic burden that negatively impacts their daily activities and well-being. Despite chronic manifestations of and problems associated with blepharitis that resulted in multiple visits to eye care providers, Demodex blepharitis remained underdiagnosed or misdiagnosed. PURPOSE This study aimed to evaluate the effect of Demodex blepharitis on patients' daily activities and well-being. METHODS This prospective, multicenter, observational study recruited 524 patients with Demodex blepharitis from 20 U.S. ophthalmology and opto

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Moskvina, Tatyana Vladimirovna. "Two morphologically distinct forms of Demodex mites found in dogs with canine demodicosis from Vladivostok, Russia." Acta Veterinaria 67, no. 1 (2017): 82–91. http://dx.doi.org/10.1515/acve-2017-0008.

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AbstractThe aim of this study was to investigate the morphology of Demodex canis and Demodex sp. cornei found in six dogs with canine demodicosis. A deep skin scraping technique was used for Demodex mite detection. Measurement data of 52 adult D. canis mites (26 females, 25 males and one specimen whose sex could not be determined) and 39 adult Demodex sp. cornei mites (22 females, 14 males and three specimens whose sex could not be determined) were reported. The correlation between body size of both Demodex species were estimated by the Student’s t-test. There was a significant correlation bet

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Chatterjee, Sumana, Jaya Gupta, Sanjeev P. Srinivas, and Srinivas K. Rao. "Demodex and the eye – A review." Indian Journal of Ophthalmology 73, no. 1 (2024): 10–18. https://doi.org/10.4103/ijo.ijo_1591_24.

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Demodex blepharitis (DB) has become one of the common differential diagnoses in patients presenting with red eyes in daily clinics. In this review article, we have incorporated a detailed discussion about the mite and the various mechanisms by which it causes different signs and symptoms, the risk factors, and diagnostic methods with current and emerging treatment modalities. Because of the chronic symptoms and rather a late diagnosis, DB considerably affects patients’ quality of life. The clues to identify cylindrical dandruff, the diagnostic sign of Demodex, visualization of the mite correla

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Luo, Susan, Cat Burkat, and Suzanne W. van Landingham. "Case of Angular Blepharitis Caused by Demodex folliculorum." American Journal of Cosmetic Surgery 38, no. 3 (2021): 139–42. http://dx.doi.org/10.1177/0748806820985762.

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Angular blepharitis is inflammation of the eyelid skin at the lateral canthus, most commonly caused by Staphylococcus and Moraxella species. The Demodex mite is an external parasite that often infests the human eyelid margin and has been implicated in both anterior and posterior blepharitis. The authors describe the case of a 43-year-old female who presented for evaluation of a 3-month history of bilateral canthal eyelid irritation, consistent with angular blepharitis. This is a case report and review of relevant literature. Skin biopsy showed evidence of Demodex folliculorum infestation. Mult

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Naharia, Pooja, Pradeep Kumar, Puneet Bhatt, et al. "Demodex mite blepharitis; Look for the mite you might have." Indian Journal of Medical Microbiology 55 (May 2025): 100861. https://doi.org/10.1016/j.ijmmb.2025.100861.

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Sgarbossa, Rayane Sol Amaral Silva, Gisele Vieira Sechi, Bruna Duarte Pacheco, et al. "The epidemiological and clinical aspects of Demodex injai demodicosis in dogs: a report of eight cases." Semina: Ciências Agrárias 38, no. 5 (2017): 3387. http://dx.doi.org/10.5433/1679-0359.2017v38n5p3387.

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The mite Demodex injai causes demodicosis, an uncommon, chronic, and recurrent parasitic dermatopathy in dogs. Demodicosis is characterized by an excessive proliferation of the Demodex injai mite in the pilosebaceous unit. Typically, demodicosis occurs in adults, and is associated with an underlying disease or a specific host immunodeficiency. Here, we describe the epidemiological, clinical, dermatological, and therapeutic aspects of Demodex injai demodicosis in dogs (n=8) at the Hospital Unit for Companion Animals of the Pontifical Catholic University of Paraná in Brazil. The affected dogs we

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Hallur, Vinaykumar, Gagandeep Singh, Shivaprakash M. Rudramurthy, Rakesh Kapoor, and Arunaloke Chakrabarti. "Demodex mite infestation of unknown significance in a patient with rhinocerebral mucormycosis due to Apophysomyces elegans species complex." Journal of Medical Microbiology 62, no. 6 (2013): 926–28. http://dx.doi.org/10.1099/jmm.0.054338-0.

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Demodex mites have been reported in the past as a cause of facial rash in immunosuppressed patients. Here, we report an interesting case of possible demodicosis associated with rhinocerebral mucormycosis. The association of mites with a fungus was detected on direct microscopic examination of the scrapings of a nasal ulcer. The mite and the fungus were identified as Demodex folliculorum and Apophysomyces elegans species complex, respectively.

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Doğan, Salih, and Sibel Doğan. "An accidental finding of a demodectic mite on a slide: Demodex folliculorum (Simon) (Acari: Demodecidae)." Systematic and Applied Acarology 24, no. 5 (2019): 962. http://dx.doi.org/10.11158/saa.24.5.16.

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Yüksel, Serkan, and Esra Pancar Yüksel. "Increased Demodex Density in Patients Hospitalized for Worsening Heart Failure." Journal of Personalized Medicine 10, no. 2 (2020): 39. http://dx.doi.org/10.3390/jpm10020039.

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Infection is an important factor leading to the exacerbation of heart failure (HF), resulting in hospitalization. Demodex species are obligatory parasites in human skin, and increased density was reported in immunocompromised patients. In this study, we aimed to investigate the Demodex density in hospitalized HF patients compared to that of healthy controls. Methods: This study included 36 HF patients and 36 age and sex-matched healthy controls. Five standardized biopsies were taken from the face of participants and assessed for Demodex by a light microscope. Results: At least one Demodex mite

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Pawełczyk, Olga. "Treatment options of human demodicosis." Journal of Education, Health and Sport 76 (December 31, 2024): 56556. https://doi.org/10.12775/jehs.2024.76.56556.

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Background: Human demodicosis is a parasitic disease caused by two species of mites, Demodex folliculorum and Demodex brevis. Cutaneous and ocular demodicosis most often occurs in a situation of impaired immune response, where the attacked organism is weakened, has reduced immunity or metabolic disorders. The treatment of demodicosis can last up to several months and requires a lot of patience and regularity from the patient. Objective: The aim of this paper is to review the therapeutic options used in the treatment of the ocular and cutaneous human demodicosis. Materials and methods: This rev

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Gonzalez-Salinas, Roberto, Elizabeth Yeu, Mark Holdbrook, et al. "Safety and Efficacy of Topical Lotilaner Ophthalmic Solution 0.25% for the Treatment of Demodex Blepharitis: A Pilot Study." Journal of Ophthalmology 2021 (September 21, 2021): 1–7. http://dx.doi.org/10.1155/2021/3862684.

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Purpose. Evaluate safety and efficacy of topical lotilaner ophthalmic solution, 0.25% for the treatment of Demodex blepharitis. Patients and Methods. 15 patients with Demodex blepharitis, defined as >10 collarettes on the upper lid, lid margin erythema, and Demodex density of ≥1.5 mites/lash on microscopy, were treated bid for 28 days with lotilaner ophthalmic solution, 0.25%. Contact lens wear, artificial eyelashes, and lid structural abnormalities were among the exclusion criteria. No other antibacterial, antiparasitic, or anti-inflammatory treatment or lid hygiene products were permitted

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Valandro, Marilia Avila, João Paulo Da Exaltação Pascon, Maria Lígia De Arruda Mistieri, and Tiago Gallina. "Feline Demodicosis by Demodex cati." Acta Scientiae Veterinariae 44, no. 1 (2016): 4. http://dx.doi.org/10.22456/1679-9216.82810.

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Background: Feline demodicosis is considered an uncommon dermatopathy in cats that is mainly caused by the mite Demodex cati, but in few cases D. gatoi may be involved. Although the clinical aspects and pathogeny of feline demodicosis are not completely understood, its clinical expression is believed to be associated with the presence of primary immunosuppressive agents. Thus, the aim of this study is to report the diagnosis and treatment of an infested cat by D. cati, associated with mixed intestinal parasitic infection. Case: An approximately 1-year-old male short hair cat which was grown in

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Hallab, I., H. Titou, O. Boudi, R. Frikh, N. Hjira, and M. Boui. "Facial Acneiform Eruption Resistant to Standard Acne Medication: Signs that Should Alert Clinicians to the Diagnosis of Demodicosis." Saudi Journal of Pathology and Microbiology 7, no. 3 (2022): 101–3. http://dx.doi.org/10.36348/sjpm.2022.v07i03.002.

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All acneiform eruptions are not acne vulgaris. Some acneiform eruptions can be caused by fungal organisms that are usually not resolved with standard acne medications. Demodex is a skin mite, taking advantage of local and general factors to proliferate. They are ubiquitous in the skin but there is a predilection for the face. The diagnosis of demodicosis is based on a range of clinical, parasitological and therapeutic arguments. Screening for Demodex sp is essential to establish the correct diagnosis and ensure suitable treatment.

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Popova, D. A., and Yu V. Kursakova. "Some aspects of laboratory diagnostics of ophthalmodemodecosis." Acta Biomedica Scientifica 9, no. 1 (2024): 142–50. http://dx.doi.org/10.29413/abs.2024-9.1.15.

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Demodicosis occupies a leading position among all dermatoses. According to ICD-10, it is not distinguished as a separate disease; it belongs to the class of parasitic diseases. The relevance of studying the problem of ophthalmodemodecosis is caused by its high prevalence and contagiousness, chronic course, an open issue of the role of the Demodex mite in the occurrence of inflammatory eye diseases, as well as the lack of effective methods for treating and preventing this pathology. In addition, Demodex causes discomfort and contributes to the occurrence of cosmetic defects, which in turn worse

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Sharara, Manal A., Kariman S. Abdel Hamid, and Adel A. Imam. "Efficacy of single-dose oral ivermectin in treatment of rosacea in relation to demodex mites." Egyptian Journal of Dermatology and Venereology 44, no. 3 (2024): 192–99. http://dx.doi.org/10.4103/ejdv.ejdv_70_23.

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Background Rosacea is a common chronic inflammatory cutaneous disease. Demodex mites play an important role in the etiology and pathogenesis of rosacea. Despite the various therapeutic options available, rosacea can be difficult to treat in some patients. Topical Ivermectin is approved for the treatment of rosacea. However, oral Ivermectin has not been extensively studied in the treatment of rosacea. This study aimed to (a) evaluate the efficacy, safety, adverse effects, and patient satisfaction of a single 250 µg/kg dose of oral ivermectin in the treatment of different subtypes of rosacea and

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Morris, Mariya G., Rodolfo J. Ricart Arbona, Kathleen Daniels, et al. "Mite Burden and Immunophenotypic Response to Demodex musculi in Swiss Webster, BALB/c, C57BL/6, and NSG Mice." Comparative Medicine 70, no. 4 (2020): 336–48. http://dx.doi.org/10.30802/aalas-cm-19-000097.

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Detection methods for Demodex musculi were historically unreliable, and testing was rarely performed because its prevalence in laboratory mice was underestimated. Although infestations are unapparent in most mouse strains, D. musculi burdens are higher and clinical signs detected in various immunodeficient strains. The parasite's influence on the immune system of immunocompetent mice is unknown. We characterized mite burden (immunocompetent and immunodeficient strains) and immunologic changes (immunocompetent strains only) in naïve Swiss Webster (SW; outbred), C57BL/6NCrl (B6; Th1 responder),

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Desire, Galaxy M., Anna M. Stagner, Li-Wei Lin, and Daniel R. Lefebvre. "“Demodicosis” Mimicking PreSeptal Cellulitis: Severe Periocular and Facial Inflammation Caused by “Normal” Skin Flora." Ophthalmic Plastic & Reconstructive Surgery 40, no. 3 (2024): e72-e74. http://dx.doi.org/10.1097/iop.0000000000002590.

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Due to their relatively high prevalence and commensalism, the pathogenicity of Demodex mites has been debated. Recent data, however, show Demodex to be associated with skin and ocular surface diseases such as rosacea, blepharitis, and keratitis. Here the authors report the first known case, to the best of the their knowledge, of Demodex infestation mimicking preseptal cellulitis in an adult human. A 29-year-old male bilaterally blind from advanced retinopathy of prematurity presented with a 2-month history of right-greater-than-left upper eyelid and periocular/cheek swelling, redness, and ocul

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Lam, Nelson Siu Kei, Xin Xin Long, Xuegang Li, Li Yang, Robert C. Griffin, and James CG Doery. "Comparison of the efficacy of tea tree (Melaleuca alternifolia) oil with other current pharmacological management in human demodicosis: A Systematic Review." Parasitology 147, no. 14 (2020): 1587–613. http://dx.doi.org/10.1017/s003118202000150x.

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AbstractVarious treatments are found to be moderately effective in managing Demodex-related diseases except tea tree oil (TTO) and terpinen-4-ol (T4O), which showed superior miticidal and anti-inflammatory effects in numerous clinical studies. Their possible effects include lowering mite counts, relieving Demodex-related symptoms, and modulating the immune system. This review summarizes the current clinical topical and oral treatments in human demodicosis, their possible mechanisms of action, side-effects and resistance in treating this condition. TTO (especially T4O) is found to be the most e

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Hillier, Andrew, and Clifford E. Desch. "Large-bodied Demodex mite infestation in 4 dogs." Journal of the American Veterinary Medical Association 220, no. 5 (2002): 623–27. http://dx.doi.org/10.2460/javma.2002.220.623.

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Udomwech, Lunla, Weeratian Tawanwongsri, and Auemphon Mordmuang. "Chicago sky blue gel for better visualization of Demodex in patients with Demodex blepharitis." PeerJ 11 (November 17, 2023): e16378. http://dx.doi.org/10.7717/peerj.16378.

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Background Demodex blepharitis is a common chronic disease. The number of mites is associated with ocular discomfort. The accurate number derived from well-stained specimens is, hence, in favor of diagnosing, monitoring, and determining treatment responses. Methods A cross-sectional study was conducted between April and July 2022 at the dermatology and ophthalmology clinic, Walailak University, Thailand. Adult participants with clinical suspicion of Demodex blepharitis were recruited. We examined eyelashes under light microscopy to quantify the number of Demodex mites before and after adding C

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Yanchenko, S. V., A. V. Malyshev, Sh Zh Teshaev, G. R. Odilova, and G. B. Zhuraeva. "Demodex blepharitis: literature review." Russian Journal of Clinical Ophthalmology 25, no. 1 (2025): 20–28. https://doi.org/10.32364/2311-7729-2025-25-1-3.

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The Demodex mite is one of the most common microscopic ectoparasites, and it is currently believed to be a cause of at least 60% of all cases of blepharitis. Demodex blepharitis and associated changes of ocular surface such as meibomian gland dysfunction (MGD) and ‘'dry eye'' syndrome (DES) caused by lipid deficiency and increased evaporation of the tear film, lead to a patient's "quality of life" deterioration. Also, they may induce ophthalmic surgery complications. Typically, metronidazole (as a local and systematic therapeutic agent), as well as sulfur- and tea tree oil-based preparations a

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Fesseha, Haben, Getero Gamo, Mesfin Mathewos, and Endale Mekonnen. "Survey on Mite Infestations in Small Ruminants in Kindo Didaye District, Wolaita zone, Southern Ethiopia." Environmental Health Insights 16 (January 2022): 117863022211272. http://dx.doi.org/10.1177/11786302221127262.

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Background: Mange is a parasitic skin disease caused by microscopic mites that feed on the skin of small ruminants and affect animal productivity. Methods: A study was carried out to determine the prevalence and possible risk factors for mite infestation in small ruminants in Kindo Didaye district, Wolaita zone, southern Ethiopia. Skin scraping samples were collected from 384 small ruminants (196 goats and 188 sheep) for the identification of mite species following the standard parasitological protocol. Results: Of the 384 examined animals, 6.25% of sheep and goats were infested with different

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Wieteska, Małgorzata, Dominik Maj, Adrianna Gorecka, Anna Gorajek, Monika Wacławska, and Aleksandra Chałupnik. "The role of Demodex folliculorum in pathogenesis of rosacea." Journal of Education, Health and Sport 12, no. 6 (2022): 105–11. http://dx.doi.org/10.12775/jehs.2022.12.06.010.

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Introduction and objective: Rosacea is a common chronic inflammatory disease that affects approximately 10% of the population globally. The exact pathogenesis of rosacea remains unknown. However, there are considered several factors such as genetic predisposition, environmental impact, immune dysregulation, as well as presence of microorganisms. The aim of the study is to review recent knowledge about the relationship between rosacea and Demodex folliculorum. The information used in the presented analysis was obtained by searching academic research databases: Google Scholar and PubMed. A

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Rychlik, Katarzyna, Julia Sternicka, Monika Zabłotna, Roman J. Nowicki, Leszek Bieniaszewski, and Dorota Purzycka-Bohdan. "The Prevalence of Demodex spp. Infestation in Dermatological Patients in Northern Poland." Life 14, no. 9 (2024): 1196. http://dx.doi.org/10.3390/life14091196.

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The presence of Demodex spp. mites on the skin is a common phenomenon in the human population. In most people, it is an asymptomatic infestation, but in some patients, it can contribute to the occurrence of diseases such as demodicosis, rosacea, or blepharitis, as well as non-specific symptoms. In this study, the results of tests assessing the presence of Demodex spp. by direct microscopic examination (DME) in 2508 patients from northern Poland with the suspicion of demodicosis were retrospectively analyzed. A total of 3684 tests were performed. Among them, only 1585 (43.02%) revealed the pres

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Davey, Pinakin Gunvant, Marjan Farid, Paul Karpecki, et al. "Lotilaner Ophthalmic Solution, 0.25%, for the Treatment of Demodex Blepharitis." Healthcare 12, no. 15 (2024): 1487. http://dx.doi.org/10.3390/healthcare12151487.

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Demodex blepharitis, a chronic lid margin disease, is caused by an infestation of Demodex mites, the most common ectoparasites in human skin and eyelids. Lotilaner ophthalmic solution, 0.25% (Xdemvy, Tarsus Pharmaceuticals), is the first therapy approved to treat Demodex blepharitis. This narrative review characterizes lotilaner ophthalmic solution, 0.25%, and describes its efficacy, safety, and tolerability. The safety and efficacy of lotilaner ophthalmic solution, 0.25%, for treating Demodex blepharitis was evaluated in four phase 2 and two phase 3 trials. The data of 980 patients included i

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Heo, Seung, and Jae-Min Choi. "Demodicidosis of an Intertragic Notch of the Ear That Was Misdiagnosed as a Skin Tumor: A Case Report." Journal of Wound Management and Research 19, no. 2 (2023): 157–60. http://dx.doi.org/10.22467/jwmr.2023.02439.

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<i>Demodex</i> mite infestation has variable clinical manifestations including eruptions, erythema, pustules, facial hyperpigmentation, rosacea-like lesions, and perioral dermatitis. A 62-year-old man came with a 2-year history of a slowly enlarging, asymptomatic lesion in the intertragic notch of the left ear, and the findings from an ultrasound conducted by a radiologist suggested a benign skin tumor such as an epidermal or trichilemmal cyst. After total excision, histopathology of a section of the specimen showed multiple follicular infundibula containing <i>Demodex</i&

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Capasso, Luigi, Giulia Abbinante, Alessia Coppola, Giulio Salerno, and Maddalena De Bernardo. "Recent Evidence of Tea Tree Oil Effectiveness in Blepharitis Treatment." BioMed Research International 2022 (July 30, 2022): 1–6. http://dx.doi.org/10.1155/2022/9204251.

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The purpose of our study is to see how beneficial is tea tree oil (TTO) for treating chronic blepharitis topically, with a focus on the Demodex mite. To discover all possibly relevant published papers, an accurate Pubmed database search analysis of the current literature was undertaken from 2012 to December 2021. Fourteen papers dealing with the use of TTO to treat chronic blepharitis have been found. The effectiveness of TTO treatment was tested in vitro by 4 authors and in vivo by 10 authors. All studied confirmed efficacy of TTO treatment, even cyclic, on Demodex mite blepharitis. TTO can b

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Balusupati Indhu Teja, Jyothi. J.,, Sangeetha. A, Balakrishna, A, and Satish Kumar . K. "Management of pyoderma associated with demodicosis in a dog- A case report." Indian Journal of Veterinary Medicine 44, no. 1 (2024): 41–42. http://dx.doi.org/10.56093/ijvm.v44i1.152608.

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Demodicosis is a very common parasitic skin disease caused by the mite Demodex canis. Demodecosis can occur in dogs of all ages. One-year-old adult male dog was presented with a history of pruritis and clinical signs such as alopecia, erythema and pustules on the face with keratinization of forelimbs and ventral side of the abdomen. Impression smear revealed Staphylococcus bacteria when stained with gram stain. Deep skin scrapping examination revealed presence of Demodex canis. Treatment with ivermectin, external application of amitraz, cephalexin, vitamin supplement with liver extract, was su

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PENA, Gil Patrus, and José de Souza ANDRADE FILHO. "Is Demodex really non-pathogenic?" Revista do Instituto de Medicina Tropical de São Paulo 42, no. 3 (2000): 171–73. http://dx.doi.org/10.1590/s0036-46652000000300012.

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Although usually considered a non-pathogenic parasite in parasitological textbooks, Demodex folliculorum has been implicated as a causative agent for some dermatological conditions, such as rosacea-like eruptions and some types of blepharitis. Several anecdotal reports have demonstrated unequivocal tissue damage directly related to the presence of the parasite. However, this seems to be exceedingly rare, in contrast with the marked prevalence of this infestation. We have had the opportunity to observe one of such cases. A 38-year-old woman presented with rosacea-like papular lesions in her rig

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Ilie, Marius Stelian, Mirela Imre, Simona Giubega, Iasmina Luca, Tiana Florea, and Sorin Morariu. "Feline Demodicosis Case Report—First Molecular Characterization of Demodex Mites in Romania." Pathogens 10, no. 11 (2021): 1474. http://dx.doi.org/10.3390/pathogens10111474.

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Cat demodicosis is uncommon to rare, and is caused by Demodex cati, Demodex gatoi and another unnamed species. The investigated patient was a mix-breed, 10-year-old feline with no dermatological history. Alopecia, erythema, minor erosions and ulcerations and crusts, associated with pruritus and self-trauma, were observed on the head. Dark, agglutinated cerumen was also present in the external ear canal. The agent causing the skin condition in the feline patient was identified as being a Demodex genus mite, based on the specific, morphological characteristics noticed upon the microscopic examin

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