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Relevant bibliographies by topics / Dendritic cells Gene therapy

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Academic literature on the topic 'Dendritic cells Gene therapy'

Author: Grafiati

Published: 4 June 2021

Last updated: 14 February 2022

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Journal articles on the topic "Dendritic cells Gene therapy"

1

Ishida, Tadao, and Kohzoh Imai. "Gene therapy using dendritic cells." Drug Delivery System 15, no. 2 (2000): 98–105. http://dx.doi.org/10.2745/dds.15.98.

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Neal, Zane C., Mary Kay Bates, and Hans Herweijer. "Dramatic Expansion of Mature Dendritic Cells by Sequential Gene Therapy." Journal of Immunotherapy 28, no. 6 (2005): 657–58. http://dx.doi.org/10.1097/01.cji.0000191094.50641.c6.

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Saka, Makoto, Takayuki Amano, Koji Kajiwara, et al. "Vaccine therapy with dendritic cells transfected with Il13ra2 mRNA for glioma in mice." Journal of Neurosurgery 113, no. 2 (2010): 270–79. http://dx.doi.org/10.3171/2009.9.jns09708.

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Object The Il13ra2 gene is often overexpressed in brain tumors, making Il13ra2 one of the vaccine targets for immunotherapy of glioma. In this study, using a mouse glioma model, the authors tested the hypothesis that vaccination using dendritic cells transfected with Il13ra2 mRNA induces strong immunological antitumor effects. Methods A plasmid was constructed for transduction of the mRNAs transcribed in vitro into dendritic cells. This was done to transport the intracellular protein efficiently into major histocompatibility complex class II compartments by adding a late endosomal/lysosomal so

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Vieweg, Johannes, and Jens Dannull. "Tumor vaccines: from gene therapy to dendritic cells—the emerging frontier." Urologic Clinics of North America 30, no. 3 (2003): 633–43. http://dx.doi.org/10.1016/s0094-0143(03)00022-3.

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Robert, C., C. Klein, G. Cheng, et al. "Gene therapy to target dendritic cells from blood to lymph nodes." Gene Therapy 10, no. 17 (2003): 1479–86. http://dx.doi.org/10.1038/sj.gt.3302008.

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Kyte, Jon A., and Gustav Gaudernack. "Immuno-gene therapy of cancer with tumour-mRNA transfected dendritic cells." Cancer Immunology, Immunotherapy 55, no. 11 (2006): 1432–42. http://dx.doi.org/10.1007/s00262-006-0161-7.

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Ogawa, F., H. Iinuma, and K. Okinaga. "Dendritic Cell Vaccine Therapy by Immunization with Fusion Cells of Interleukin-2 Gene-Transduced, Spleen-Derived Dendritic Cells and Tumour Cells." Scandinavian Journal of Immunology 59, no. 5 (2004): 432–39. http://dx.doi.org/10.1111/j.0300-9475.2004.01411.x.

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Rodriguez-Lecompte, Juan Carlos, Steve Kruth, Steve Gyorffy, Yong-Hong Wan, and Jack Gauldie. "Cell-based cancer gene therapy: breaking tolerance or inducing autoimmunity?" Animal Health Research Reviews 5, no. 2 (2004): 227–34. http://dx.doi.org/10.1079/ahr200473.

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AbstractThis review examines the mechanisms involved in anti-tumor immunity and how peptides present in many tumor types (tumor-associated antigens) are recognized by T cells from tumor-bearing cancer patients. Tumor-associated antigens are derived from proteins that are also expressed in normal cells. It is predicted that immune responses to such peptides will be compromised by self-tolerance or that stimulation of effective immune responses will be accompanied by autoimmunity. We also consider that the immunity induced against two autoantigens, which are highly conserved in vertebrates, invo

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Huarte, Eduardo, Iñigo Tirapu, Ainhoa Arina, et al. "Intratumoural administration of dendritic cells: hostile environment and help by gene therapy." Expert Opinion on Biological Therapy 5, no. 1 (2005): 7–22. http://dx.doi.org/10.1517/14712598.5.1.7.

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Jooss, Karin, Yiping Yang, Krishna J. Fisher, and James M. Wilson. "Transduction of Dendritic Cells by DNA Viral Vectors Directs the Immune Response to Transgene Products in Muscle Fibers." Journal of Virology 72, no. 5 (1998): 4212–23. http://dx.doi.org/10.1128/jvi.72.5.4212-4223.1998.

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ABSTRACT Immune responses to vector-corrected cells have limited the application of gene therapy for treatment of chronic disorders such as inherited deficiency states. We have found that recombinant adeno-associated virus (AAV) efficiently transduces muscle fibers in vivo without activation of cellular and humoral immunity to neoantigenic transgene products such as β-galactosidase, which differs from the experience with recombinant adenovirus, where vibrant T-cell responses to the transgene product destroy the targeted muscle fibers. T cells activated following intramuscular administration of

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Dissertations / Theses on the topic "Dendritic cells Gene therapy"

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Lundqvist, Andreas. "Dendritic cells in immune and gene therapy against cancer /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-420-8.

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Hotblack, A. C. "Characterising the role of dendritic cells in TCR gene therapy." Thesis, University College London (University of London), 2017. http://discovery.ucl.ac.uk/1537265/.

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Adoptive transfer of T cell receptor (TCR) gene-modified T cells is a promising field of tumour immunology. However whilst these cells can potently control tumour growth, this occurs in only a subset of patients. In order to devise new strategies to improve the anti-tumour response we need a clear understanding of the mechanisms by which transferred T cells are activated to kill tumours. Whilst dendritic cells (DC) are required to activate and control T cell function in adaptive immune responses it is not known whether control of tumours by adoptively transferred T cells depends on similar int

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Coates, Patrick Toby Hewlett. "Gene therapy studies of Adenoviral IL-10 transduced Dendritic cells in allotransplantation." Title page, contents and abstract only, 2001. http://web4.library.adelaide.edu.au/theses/09PH/09phc6525.pdf.

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Bibliography: leaves 151-186. Studies the capacity of dendritic cells transduced with the immunosuppressive gene construct adenoviral interleukin-10 to inhibit alloimmune responses in both small and large animal transplantation models. There is promising in vitro evidence for gene therapy to modify dendritic cell function, which in small animal models can modify skin graft rejection. In large animals, genetically modified dendritic cells alone were not capable of prolongation of allograft survival, suggesting that these cells may require adjuvant immunosuppressive therapy to be used in future

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Anderson, B. Kevin Rice Kevin G. "Glycan targeted gene delivery to the dendritic cell SIGN receptor." [Iowa City, Iowa] : University of Iowa, 2009. http://ir.uiowa.edu/etd/328.

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Henry, Emmanuelle. "Dendritic cells genetically engineered to express IL-10 induce long-lasting antigen-specific tolerance in experimental asthma." Doctoral thesis, Universite Libre de Bruxelles, 2007. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210584.

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Dendritic cells (DCs) are professional APCs that have a unique capacity to initiate primary immune responses, including tolerogenic responses. We have genetically engineered bone marrow-derived DCs to express the immunosuppressive cytokine IL-10 and tested the ability of these cells to control experimental asthma. A single intratracheal injection of OVA-pulsed IL-10-transduced DCs (OVA-IL-10-DCs) to naive mice prior to OVA sensitization and challenge prevented all the cardinal features of airway allergy, namely eosinophilic airway inflammation, airway hyperreactivity, and production of mucus,

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Best, Victoria Maria. "Ongoing cellular responses to transgene products encoded by recombinant adeno-associated virus (rAAV) vectors." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1262213552.

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Servais, Charlotte. "Mise au point de thérapies anti-tumorales impliquant des vecteurs parvoviraux et la fusion de cellules tumorales et dendritiques." Doctoral thesis, Universite Libre de Bruxelles, 2007. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210624.

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L’immunothérapie anticancéreuse est basée sur la capacité du système immunitaire à reconnaître les cellules tumorales comme étrangères et à les éliminer. Les stratégies immunothérapeutiques abordées dans ce travail, incluent l’activation du système immunitaire par l’expression de facteurs immunomodulateurs (l’interleukine-2) via l’utilisation d’un vecteur dérivé du parvovirus MVM, ou par présentation des antigènes tumoraux par la machinerie des cellules dendritiques (DC), via la génération d’hybrides entre DC et cellules tumorales (TC).<p>L’intérêt majeur du parvovirus autonome MVM en tant que

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Klaska, Izabela. "Dendritic cell-based therapy of experimental autoimmune uveoretinitis." Thesis, University of Aberdeen, 2013. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=196130.

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Recently, there has been considerable interest in developing specific cell-based immunotherapies using dendritic cells (DCs). Here the mechanisms underlying the tolerogenic properties of DCs in the suppression of experimental autoimmune uveoretinitis (EAU), the mouse model of human sight threatening autoimmune uveitis, were examined. Immature DCs have the ability to promote immune tolerance to self antigens and to prevent the development of autoimmune disorders including EAU. However there is a risk that immature DCs placed in the inflammatory environment would undergo maturation and instead o

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Peretz, Yoav. "In vivo generation of Dendritic cells by electro-gene transfer." Thesis, McGill University, 2002. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=79111.

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Since the discovery of Dendritic cells (DCs) in 1975, their role as potent antigen presenting cells has been a field of intense interest and research. Candidate DC vaccines take advantage of the role of DCs in one of two ways. The first technique relies on the in vivo isolation of DCs which are then subsequently employed directly as adjuvants. In the second method, hematopoeitic growth factors are added to stimulate the expansion and proliferation of these cells in vivo. Due to the dearth of DCs, research has focused on the addition of growth factors such as FLT3-L (fms-like tyrosine ki

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Raïch, Regué Dàlia. "Generation of Tolerogenic Dendritic Cells for Cell Therapy in Multiple Sclerosis." Doctoral thesis, Universitat Autònoma de Barcelona, 2012. http://hdl.handle.net/10803/96710.

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L’esclerosi múltiple (EM) és considerada una malaltia autoimmune crònica que afecta el sistema nerviós central. Els tractaments actuals pels pacients amb EM remitent-recurrent (EM-RR) redueixen la freqüència dels brots i l’activitat inflamatòria general, però el seu efecte en la progressió de la malaltia encara no està clar. Per això és necessari desenvolupar noves aproximacions terapèutiques més específiques per tal de modificar el curs de la malaltia. En aquest sentit, una estratègia terapèutica interessant és la inhibició o supressió específica de les cèl·lules T autoreactives amb la finali

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Books on the topic "Dendritic cells Gene therapy"

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Sell, Stewart. Liver stem cells. Landes Bioscience, 1997.

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International Symposium on Biomedical Science and Technology (9th 2002 Antalya, Turkey). Tissue engineering, stem cells, and gene therapies. Kluwer Academic/Plenum Publishers, 2003.

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International, Symposium on Biomedical Science and Technology (9th 2002 Antalya Turkey). Tissue engineering, stem cells, and gene therapies. Kluwer Academic/Plenum Publishers, 2003.

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International Symposium on Biomedical Science and Technology (9th 2002 Antalya, Turkey). Tissue engineering, stem cells, and gene therapies. Kluwer Academic/Plenum Publishers, 2003.

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Baum, Christopher. Genetic modification of hematopoietic stem cells: Methods and protocols. Humana Press, 2009.

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Genetic modification of hematopoietic stem cells: Methods and protocols. Humana Press, 2009.

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Holzgreve, W., and M. Lessl, eds. Stem Cells from Cord Blood, in Utero Stem Cell Development and Transplantation-Inclusive Gene Therapy. Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-662-04469-8.

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The golden cell: Gene therapy, stem cells and the quest for the next great medical breakthrough. HarperPerennial, 2006.

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Kampen, Karen Van. The golden cell: Gene therapy, stem cells, and the quest for the next great medical breakthrough. HarperCollins Canada, 2005.

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Kampen, Karen Van. The golden cell: Gene therapy, stem cells, and the quest for the next great medical breakthrough. HarperCollins Canada, 2005.

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Book chapters on the topic "Dendritic cells Gene therapy"

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Han, Shuhong, and Lung-Ji Chang. "Immunity of Lentiviral Vector-Modified Dendritic Cells." In Gene Therapy of Cancer. Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-561-9_13.

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Westermann, J., A. Aicher, and A. Pezzutto. "Dendritic Cells for Somatic Gene Therapy." In Recent Results in Cancer Research. Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-46836-0_9.

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Larmonier, Nicolas, and Emmanuel Katsanis. "Dendritic Cells for Cancer Immunotherapy." In Emerging Trends in Cell and Gene Therapy. Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-417-3_11.

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de Gruijl, Tanja D., Herbert M. Pinedo, and Rik J. Scheper. "Immunotherapy of Cancer by Dendritic Cell-Targeted Gene Transfer." In Cancer Gene Therapy. Humana Press, 2005. http://dx.doi.org/10.1007/978-1-59259-785-7_10.

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Rossetti, Maura, Mariangela Cavarelli, Silvia Gregori, and Gabriella Scarlatti. "HIV-Derived Vectors for Gene Therapy Targeting Dendritic Cells." In Advances in Experimental Medicine and Biology. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-4433-6_9.

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Schadendorf, D., A. Paschen, and Y. Sun. "Genetic and Dendritic Cell Vaccination as a Novel Therapy for Melanoma." In The Skin and Gene Therapy. Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-56441-3_13.

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Lambrecht, Bart N., and Hamida Hammad. "Lung Dendritic Cells: Targets for Therapy in Allergic Disease." In Dendritic Cells. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-71029-5_5.

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Segall, Harry, and Richard E. Sutton. "Monocyte/Macrophages and Dendritic Cells." In Lentivirus Gene Engineering Protocols. Humana Press, 2003. http://dx.doi.org/10.1385/1-59259-393-3:107.

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Nestle, Frank O. "Immunotherapy of Melanoma Using Dendritic Cells." In Cell Therapy. Springer Japan, 2000. http://dx.doi.org/10.1007/978-4-431-68506-7_6.

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Licht, T., M. M. Gottesman, and I. Pastan. "MDR1 Gene Transfer to Hematopoietic Cells." In Gene Therapy. Birkhäuser Basel, 1999. http://dx.doi.org/10.1007/978-3-0348-7011-5_14.

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Conference papers on the topic "Dendritic cells Gene therapy"

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Mroz, Pawel, Ana P. Castano, and Michael R. Hamblin. "Stimulation of dendritic cells enhances immune response after photodynamic therapy." In SPIE BiOS: Biomedical Optics, edited by Wei R. Chen. SPIE, 2009. http://dx.doi.org/10.1117/12.809630.

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Babushkina, Nina. "Simplest Mathematical Model of Anti-Tumor Therapy Based on Dendritic Cells." In 2020 13th International Conference Management of large-scale system development (MLSD). IEEE, 2020. http://dx.doi.org/10.1109/mlsd49919.2020.9247754.

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Nwosu, L., K. Smith, C. Hilkens, and J. Isaacs. "P138/O10 Investigating gene expression patterns and function of tolerogenic dendritic cells." In 39th European Workshop for Rheumatology Research, 28 February–2 March 2019, Lyon, France. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2018-ewrr2019.123.

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Uribe-Herranz, Mireia, Kyle Bittinger, Stavros Rafail та ін. "Abstract 3798: Gut microbiota modulates adoptive cell therapy via CD8α dendritic cells". У Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-3798.

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Purvis, H., F. Clarke, C. Jordan, et al. "OP0296 Autoimmune associated gene PTPN22 negatively regulates DECTIN-1 signalling in dendritic cells." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.4717.

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Kurochkina, Y., M. Tikhonova, T. Tyrinova, et al. "SAT0008 Drug therapy enhances tolerogenic properties of dendritic cells in patients with rheumatoid arthritis." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.2408.

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Uribe-Herranz, Mireia, Kyle Bittinger, Stavros Rafail та ін. "Abstract 4961: Gut microbiota modulates adoptive cell therapy via CD8α dendritic cells and IL-12". У Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-4961.

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Uribe-Herranz, Mireia, Kyle Bittinger, Stavros Rafail та ін. "Abstract 4961: Gut microbiota modulates adoptive cell therapy via CD8α dendritic cells and IL-12". У Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-4961.

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Wilson, Ariel, Javier Mazzaferri, Éric Bergeron, et al. "In vivo laser targeted gene therapy of retina ganglion cells (Conference Presentation)." In Ophthalmic Technologies XXIX, edited by Fabrice Manns, Per G. Söderberg, and Arthur Ho. SPIE, 2019. http://dx.doi.org/10.1117/12.2509870.

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Papadaki, G., P. Goutakoli, JR Grün, et al. "P009 Transcriptomic analysis of plasmacytoid dendritic cells from rheumatoid arthritis patients reveals novel targets for therapy." In 38th European Workshop for Rheumatology Research, 22–24 February 2018, Geneva, Switzerland. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-ewrr2018.35.

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Reports on the topic "Dendritic cells Gene therapy"

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Chung, David J. Evaluation of Immune Responses Mediated by Listeria-Stimulated Human Dendritic Cells: Implications for Cancer Vaccine Therapy. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada612542.

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Chung, David J. Evaluation of Immune Responses Mediated by Listeria-Stimulated Human Dendritic Cells: Implications for Cancer Vaccine Therapy. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada581991.

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Yim, John H. Transcription Activator Reprogramming Gene Therapy (TARGET) of Breast Cancer Cells with Adenoviral Vectors for Interferon Regulatory Factors. Defense Technical Information Center, 2006. http://dx.doi.org/10.21236/ada484513.

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Rinne, Mikael L., and Mark R. Kelley. DNA Base Excision Repair (BER) and Cancer Gene Therapy: Use of the Human N-Methylpurine DNA Glycosylase (MPG) to Sensitive Breast Cancer Cells to Low Dose Chemotherapy. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada407383.

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