Academic literature on the topic 'Dendronized polymers'

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Journal articles on the topic "Dendronized polymers"

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Yan, Jiatao, Wen Li, and Afang Zhang. "Dendronized supramolecular polymers." Chem. Commun. 50, no. 82 (2014): 12221–33. http://dx.doi.org/10.1039/c4cc03119a.

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Boisselier, Elodie, Anita Chan Kam Shun, Jaime Ruiz, Eric Cloutet, Colette Belin, and Didier Astruc. "Ferrocenyl dendronized polymers." New Journal of Chemistry 33, no. 2 (2009): 246. http://dx.doi.org/10.1039/b819604d.

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Li, Wen, Afang Zhang, Kirill Feldman, Peter Walde, and A. Dieter Schlüter. "Thermoresponsive Dendronized Polymers." Macromolecules 41, no. 10 (May 2008): 3659–67. http://dx.doi.org/10.1021/ma800129w.

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Chen, Yongming, and Xingquan Xiong. "Tailoring dendronized polymers." Chemical Communications 46, no. 28 (2010): 5049. http://dx.doi.org/10.1039/b922777f.

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Tang, Runli, Hong Chen, Shengmin Zhou, Wendi Xiang, Xi Tang, Binwen Liu, Yongqiang Dong, Huiyi Zeng, and Zhen Li. "Dendronized hyperbranched polymers containing isolation chromophores: design, synthesis and further enhancement of the comprehensive NLO performance." Polymer Chemistry 6, no. 31 (2015): 5580–89. http://dx.doi.org/10.1039/c5py00155b.

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Mynar, Justin L., Tae-Lim Choi, Masaru Yoshida, Victor Kim, Craig J. Hawker, and Jean M. J. Fréchet. "Doubly-dendronized linear polymers." Chemical Communications, no. 41 (2005): 5169. http://dx.doi.org/10.1039/b509398h.

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Yan, Jiatao, Wen Li, Kun Liu, Dalin Wu, Feng Chen, Peiyi Wu, and Afang Zhang. "Thermoresponsive Supramolecular Dendronized Polymers." Chemistry - An Asian Journal 6, no. 12 (September 8, 2011): 3260–69. http://dx.doi.org/10.1002/asia.201100528.

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Chawla, Pooja, and Monika Mis. "Polymeric Drugs: A Novel Approach to Drug Delivery System." International Journal of Pharmaceutical Sciences and Nanotechnology 6, no. 1 (May 31, 2013): 1925–34. http://dx.doi.org/10.37285/ijpsn.2013.6.1.2.

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This review article describes the current status and recent advances of polymeric drugs with regard to their application in drug delivery system. Essentially polymer-drug conjugation aims to achieve improved drug targeting, decrease drug toxicity and overcome mechanisms of drug resistance. First generation conjugates used linear monomethoxy PEGs and other linear polymers. Modern polymeric chemistry is increasingly producing new polymeric architectures such as dendrimers, hyper branched polymers and hybrid macromolecular structures (such as star polymers, linear graft and dendronized linear polymers and novel therapeutic siRNA. This undoubtedly can be employed for designing of second generation polymer therapeutics. Clinical approval of products such as Copaxone®, Renagel®, Vivagel® and Welchol® have been successful in developing interest in polymer therapeutics as a growing field of research and development. In conclusion, there is emerging data that polymer drug conjugation has become useful in a wide range of treatments from infectious to chronic diseases such as cancer. Polymer therapeutics holds promising future applications in the field of nanotherapeutics. Polymeric Drugs: A Novel Approach to Drug Delivery System
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Zhang, Xiacong, Ting Liu, Jiatao Yan, Kun Liu, Wen Li, and Afang Zhang. "Multiple-Responsive Dendronized Hyperbranched Polymers." ACS Omega 4, no. 4 (April 26, 2019): 7667–74. http://dx.doi.org/10.1021/acsomega.9b00291.

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Chen, Yongming, and Xingquan Xiong. "ChemInform Abstract: Tailoring Dendronized Polymers." ChemInform 41, no. 46 (October 25, 2010): no. http://dx.doi.org/10.1002/chin.201046223.

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Dissertations / Theses on the topic "Dendronized polymers"

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Nyström, Andreas. "Dendrimers and dendronized polymers : synthesis and characterization." Doctoral thesis, KTH, Fiber- och polymerteknik, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3970.

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The goal of this work was to synthesize complex macromolecular architectures such as dendrimers and dendronized polymers, and evaluate the effect from the dendrons on the optical and material properties. The work presented in this doctoral thesis, Dendrimers and Dendronized Polymers - Synthesis and Characterization, is divided into one minor and one major part. The first part deals with the synthesis and characterization of two sets of dendritic porphyrins based on 2,2-bis(methylol)propionic acid (bis-MPA). The second part deals with the synthesis and characterization of dendronized poly(hydroxyl ethyl methacylate), dendronized poly(norbornene), and dendronized triblock copolymers, were the pendant dendrons are based on bis-MPA. Both free-base and zinc containing dendritic porphyrins was synthesized up to the fifth generation by employing iterative ester coupling utilizing the acetonide protected anhydride of bis-MPA as generic building block. First and second generation dendron bearing methacrylates based on 2-hydroxyethyl methacrylate were also synthesized by utilizing the acetonide protected anhydride of bis-MPA, and subsequently polymerized by atom transfer radical polymerization. By adopting a divergent “graft-to” approach starting from the first generation dendronized poly(hydroxyl ethyl methacrylate), well-defined dendronized polymers with acetonide, hydroxyl, acetate and hexadecyl surface functionality were obtained. By utilizing the same divergent iterative esterfication, first to fourth generation dendron functionalized norbornenes were synthesized. These monomers were polymerized by ring-opening metathesis polymerization, utilizing either Grubbs´ first or second generation catalyst. Acrylate functional first to fourth generation monomers were synthesized by the copper(I) catalyzed “click” coupling of azido functional dendrons and propargyl acrylate. The monomers were polymerized to dendronized triblock copolymers by reversible addition-fragmentation chain transfer polymerization, utilizing a difunctional poly(methyl methacrylate) as macro chain transfer agent. The bulk properties of the dendronized poly(hydroxyl ethyl methacrylate) and poly(norbornene) were investigated by dynamic rheological measurements and differential scanning calorimetry. It was found that all the acetonide functional bis-MPA based dendronized polymers had glass transitions temperatures in a similar range. The rheological behaviour showed that for the dendronized polymers having the same backbone length the complex viscosity as a function of functionality was independent of the surface functionality of the polymer. The generation number of the polymer had a profound influence on the complex viscosity, changing form a Newtonian behaviour to a shear thinning behaviour when the generation of the dendrons was increased from two to four. The dendronized poly(norbornene) had increasingly shorter backbone lengths for each generational increase, and for the materials set with comparably lower degree of polymerization, the G’ part of the complex modulus was mostly affected by attaching larger dendrons. In the case of the sample set of higher degree of polymerization, the second, third, and fourth generation samples had similar slopes of the G’ and G” curves, indicating a similar relaxation behaviour.
QC 20100914
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Nyström, Andreas. "Dendrimers and dendronized polymers : synthesis and characterization /." Stockholm, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3970.

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Yi, Ding. "Multiscale modeling structure and super structures of dendronized polymers /." Zürich : ETH, 2008. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=18126.

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Al-Hellani, Rabie. "Orthogonally protected dendronized polymers : synthesis, characterization and chemical modification /." Zürich : ETH, 2007. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17407.

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Gössl, Illdiko Maria. "Supramolecular structures of dendronized polymers and DNA on solid substrates." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=968755925.

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Gössl, Illdiko Maria. "Supramolecular structures of dendronized polymers and DNA on solid substrates." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2003. http://dx.doi.org/10.18452/14893.

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Komplexe aus entgegengesetzt geladenen Polyelektrolyten haben sowohl in der Biologie als auch in den Materialwissenschaften eine große Bedeutung. Im Mittelpunkt des Interesses stehen besonders die Kondensation der DNA in vitro, die Struktur des Nukleosoms im Zellkern, nicht-virale Systeme zur Transfektion von DNA in Zellen oder der Vorgang der layer-by-layer Adsorption. Verschiedene Theorien befassen sich mit den treibenden Kräften solcher Komplexbildungen. Allerdings standen experimentelle Untersuchungen auf diesem Gebiet bisher noch aus. Dieser Arbeit liegt die Fragestellung zu Grunde, ob es mit Hilfe der Rasterkraftmikroskopie möglich ist, die Struktur einzelner Polyelektrolytkomplexe, bestehend aus den beiden Polyelektrolyten DNA und dendronisierten Polymer, aufzuklären und ihre Komplexbildung zu untersuchen. Die Komplexe bildeten sich in Lösung und wurden anschließend auf einer unbeschichteten oder mit positiven Polymeren beschichteten Glimmeroberfläche adsorbiert. Auf der positiv beschichteten Glimmeroberfläche hafteten DNA-dendronisierte Polymer Komplexe mit einem Ladungsverhältnis von 1:1 bis 1:0.7 (DNA:dendronisiertes Polymer). Anhand der hochaufgelösten rasterkraftmikroskopischen Aufnahmen wurde ein Modell entwickelt, das die Umwicklung der DNA um das dendronisierte Polymer beschreibt. Der DNA-DNA Abstand ergab sich zu (2.30 ± 0.27) nm für den Komplex mit DNA und zweiter Generation dendronisierter Polymere und zu (2.16 ± 0.27) nm mit vierter Generation. Die theoretische Vorhersage der Überladung der Komplexe konnte experimentell bestätigt werden. Mit Hilfe der Rasterkraftmikroskopie konnte überdies der Einfluss des Salzgehaltes der Lösung auf die Bildung der Komplexe mit DNA und zweiter Generation dendronisierter Polymere untersucht werden. Wie man anhand des Zusammenwirkens von elektrostatischen Kräften und entropischen Wechselwirkungen bei der Adsorption von Polyelektrolyten vorhersagen kann, durchlief der DNA-DNA Abstand ein Minimum bei ansteigendem Salzgehalt. Bei sehr hohem Salzgehalt (2.4 M NaCl) konnte das Ablösen der DNA von dem Komplex beobachtet werden. Die untersuchten DNA/dendroniserten Polymer Komplexe bilden ein neues Modellsystem, mit dem einzelne Polyelektrolyt-Wechselwirkungen direkt untersucht werden können. Ein Vergleich der experimentellen Daten mit den vorhandenen Theorien zeigte, dass der Prozess des Überladens weitgehend durch elektrostatische Wechselwirkung zwischen den beiden Polyelektrolyten beschrieben werden kann. Sowohl entropische Beiträge als auch die Biegeenergie der umwickelnden DNA sind vernachlässigbar. Basierend auf diesen Ergebnissen können neue Trägerstrukturen für effizientere nicht-virale DNA-Transfektionssysteme entwickelt werden.
Complexes of oppositely charged polyelectrolytes play an important role in both biology and material science, for instance DNA condensation in vitro, nucleosomal structure, non-viral gene transfection systems as well as layer-by-layer adsorption. Although there are theories predicting overcharging of polyelectrolyte complexes, the driving forces are still under debate and systematic experimental studies on single polyelectrolytes remain challenging. Therefore the question arose if it is possible to analyze single polyelectrolyte complexes, using DNA and dendronized polymers, with the scanning force microscope in order to investigate the complexation in detail. For the complex analysis, the polyelectrolytes were allowed to interact in solution and then to adsorb on negatively charged mica or on mica coated with a positively charged polymer. Scanning force microscopy was used to investigate the adsorbed species. DNA/dendronized polymer complexes of charge ratio of 1/1 through 1/0.7 adsorbed on mica coated with a positively charged polymer. The analysis of high resolution molecular images indicated that DNA wraps around the dendronized polymer with an estimated pitch of (2.30 ± 0.27) nm and (2.16 ± 0.27) nm for dendronized polymers of generation two and four, respectively. In the proposed model the polyelectrolyte with the smaller linear charge density is wrapped around the more highly charged dendronized polymer, resulting in a negatively overcharged complex. This overcharging is consistent within recent theories of spontaneous overcharging of complexes of one polyelectrolyte wrapping around the other. Using the complex of DNA and dendronized polymers of second generation, the influence of monovalent salt concentration on the molecular structure was studied. By increasing the salt concentration the pitch showed a minimum as predicted by the interplay of electrostatic forces and entropic interactions of polyelectrolyte adsorption. At high salt concentration (2.4 M NaCl) the release of DNA from the complex can be observed. The results showed that the DNA/dendronized polymer system can be used as a new, high potential model system to investigate single polyelectrolyte interactions. With regard to recent theories, the experimental results indicate that the overcharging of the complex is mainly driven by electrostatic forces whereas contributions of counterion entropy and bending energy seem to be negligible. This understanding may be useful for the design of single polyelectrolyte complexes for non-viral gene delivery systems and might help to optimize the transfection efficiency based on the structure of the vector system.
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Sisk, David Theodore. "I. Tunable Luminescence in Dendronized Poly(phenyleneethynylene)s Through Post-Polymerization Chemical Modification II. Rigid, Helical Polymers Based Upon Chiral Hydrobenzoin." Diss., The University of Arizona, 2007. http://hdl.handle.net/10150/194768.

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Dendritic encapsulation of poly(phenyleneethynylene)s or PPEs has been shown to enhance photoluminescent quantum efficiency and facilitate energy transfer by funneling photonic energy absorbed on the dendron periphery efficiently to the conjugated polymeric core. The research presented herein focuses on incorporating degradable dendron onto PPEs, examining whether or not similar benefits were conferred upon the proposed system and controlling polymer luminescence through the elimination of the insulating macromolecules. PPEs appended with disassembling dendrons of various generation sizes were synthesized and their optical properties studied. Polymer luminescence was then quenched via chemical degradation of the disassembling dendrons. Furthermore, the macromolecules resulting from disassembly exhibited tunable luminescence properties upon manipulation of pH. Consequently, it was determined that polymer luminescence could be controlled upon forming phenolic moieties along the PPE backbone. Tunable emission was later realized in the thin film as well through the integration of crosslinkable dendrons onto the polymer core.Recently, helical synthetic linear polymers have demonstrated the ability to facilitate stereoselective processes such as catalysis, recognition and separation. Consequently, it has become increasingly desirable to develop new platforms capable of imparting asymmetry. The work presented herein describes the synthesis of a series of polymers based upon chiral hydrobenzoin and the subsequent conformational analysis performed on these materials. It was envisioned that these polymeric materials might inherently possess conformational asymmetry and as result could be able to impart configurationally chirality by introducing a diastereomeric bias for the formation of one enantiomer over the other during the course of the reaction.
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Kasëmi, Edis. "Efficient synthesis of homologous series of dendrons, dendrimers and dendronized polymers for supramolecular solution and bulk phase applications /." Zürich : ETH, 2007. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17344.

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Kasemi, Edis. "Efficient synthesis of homologous series of dendrons, dendrimers and dendronized polymers for supramolecular solution and bulk phase applications." kostenfrei, 2007. http://e-collection.ethbib.ethz.ch/view/eth:29925.

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Fleischmann, Sven. "Alkinhaltige Blockcopolymere und ihre Modifizierung mittels 1,3-dipolarer Cycloaddition." Doctoral thesis, München Verl. Dr. Hut, 2008. http://d-nb.info/991285212/04.

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Book chapters on the topic "Dendronized polymers"

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Junk, Matthias J. N. "Local Nanoscopic Heterogeneities in Thermoresponsive Dendronized Polymers." In Assessing the Functional Structure of Molecular Transporters by EPR Spectroscopy, 149–72. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-25135-1_7.

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Rudick, Jonathan G. "Nanomechanical Function Arising from the Complex Architecture of Dendronized Helical Polymers." In Hierarchical Macromolecular Structures: 60 Years after the Staudinger Nobel Prize II, 345–62. Cham: Springer International Publishing, 2013. http://dx.doi.org/10.1007/12_2013_241.

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Benhabbour, S. Rahima, and Alex Adronov. "Synthesis and Characterization of Carborane Functionalized Dendronized Polymers as Potential Boron Neutron Capture Therapy Agents." In ACS Symposium Series, 238–49. Washington, DC: American Chemical Society, 2008. http://dx.doi.org/10.1021/bk-2008-0977.ch014.

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Xiong, Xingquan, and Yongming Chen. "Dendronized Copolymers." In Encyclopedia of Polymeric Nanomaterials, 547–54. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-29648-2_21.

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Zhang, Baozhong, and A. Dieter Schlüter. "Dendronized Homopolymers." In Encyclopedia of Polymeric Nanomaterials, 554–59. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-29648-2_22.

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Xiong, Xingquan, and Yongming Chen. "Dendronized Copolymers." In Encyclopedia of Polymeric Nanomaterials, 1–8. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-36199-9_21-4.

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Zhang, Baozhong, and A. Dieter Schlüter. "Dendronized Homopolymers." In Encyclopedia of Polymeric Nanomaterials, 1–7. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-36199-9_22-1.

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Li, Wen, Jiatao Yan, and Afang Zhang. "Dendronized Block Copolymers." In Encyclopedia of Polymeric Nanomaterials, 540–47. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-29648-2_20.

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Li, Wen, Jiatao Yan, and Afang Zhang. "Dendronized Block Copolymers." In Encyclopedia of Polymeric Nanomaterials, 1–9. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-36199-9_20-2.

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Küchler, Andreas, Daniel Messmer, A. Dieter Schlüter, and Peter Walde. "Preparation and Applications of Dendronized Polymer–Enzyme Conjugates." In Methods in Enzymology, 445–74. Elsevier, 2017. http://dx.doi.org/10.1016/bs.mie.2017.01.014.

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Conference papers on the topic "Dendronized polymers"

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Radić, D., L. Alegría, C. Sandoval, and L. Gargallo. "Synthesis, characterization and molecular dynamic simulation on dendronized poly(diphtalimidoalky phenyl) methacrylates." In 6TH INTERNATIONAL CONFERENCE ON TIMES OF POLYMERS (TOP) AND COMPOSITES. AIP, 2012. http://dx.doi.org/10.1063/1.4738483.

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Schmidt, Mathias, Nancy Alvarado, Luz Alegría, César Saldías, Irma Fuentes, Pamela Menares, Ligia Gargallo, Angel Leiva, and Deodato Radić. "Non-steroidal anti-inflamatory drugs as guest of dendronized polymeric nanocomposites." In VIII INTERNATIONAL CONFERENCE ON “TIMES OF POLYMERS AND COMPOSITES”: From Aerospace to Nanotechnology. Author(s), 2016. http://dx.doi.org/10.1063/1.4949691.

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Jansen-van Vuuren, Ross D., Pegah Maasoumi, Ebinazar B. Namdas, and Paul L. Burn. "The development of dendronized polymers containing phosphorescent iridium(III) complexes for solution-processable OLED Devices." In Solid-State and Organic Lighting. Washington, D.C.: OSA, 2014. http://dx.doi.org/10.1364/soled.2014.dw5c.4.

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Luo, Jingdong, Sen Liu, Marnie Haller, Hongxiang Li, Tae-Dong Kim, Kyoung-Soo Kim, Hong-Zhi Tang, et al. "Recent progress in developing highly efficient nonlinear optical chromophores and side-chain dendronized polymers for electro-optics." In Integrated Optoelectronics Devices, edited by James G. Grote and Toshikuni Kaino. SPIE, 2003. http://dx.doi.org/10.1117/12.475459.

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