Relevant bibliographies by topics / Dental caries Antibacterial agents. Nanoparticles

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Academic literature on the topic 'Dental caries Antibacterial agents. Nanoparticles'

Author: Grafiati

Published: 4 June 2021

Last updated: 18 February 2022

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Journal articles on the topic "Dental caries Antibacterial agents. Nanoparticles"

Song, Wenjing, and Shaohua Ge. "Application of Antimicrobial Nanoparticles in Dentistry." Molecules 24, no. 6 (March 15, 2019): 1033. http://dx.doi.org/10.3390/molecules24061033.

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Oral cavity incessantly encounters a plethora of microorganisms. Plaque biofilm—a major cause of caries, periodontitis and other dental diseases—is a complex community of bacteria or fungi that causes infection by protecting pathogenic microorganisms from external drug agents and escaping the host defense mechanisms. Antimicrobial nanoparticles are promising because of several advantages such as ultra-small sizes, large surface-area-to-mass ratio and special physical and chemical properties. To better summarize explorations of antimicrobial nanoparticles and provide directions for future studies, we present the following critical review. The keywords “nanoparticle,” “anti-infective or antibacterial or antimicrobial” and “dentistry” were retrieved from Pubmed, Scopus, Embase and Web of Science databases in the last five years. A total of 172 articles met the requirements were included and discussed in this review. The results show that superior antibacterial properties of nanoparticle biomaterials bring broad prospects in the oral field. This review presents the development, applications and underneath mechanisms of antibacterial nanoparticles in dentistry including restorative dentistry, endodontics, implantology, orthodontics, dental prostheses and periodontal field.

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Idorași, Laura, Laura Cîrligeriu, Cosmin Sinescu, Cristian Zaharia, Adrian Tudor Stan, and Meda Lavinia Negruțiu. "Silver Nanotechnology — the Future in Caries Therapy? A Report of Two Cases." Journal of Interdisciplinary Medicine 2, no. 1 (March 1, 2017): 67–71. http://dx.doi.org/10.1515/jim-2017-0034.

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AbstractIntroduction: Dental decays remain the most common and rampant biofilm-dependent oral disorders. Influencing the delicate dynamic between demineralization and remineralization is a big challenge in clinical practice, and nanotechnology is considered a viable solution. The therapeutic management of caries, which includes nanotechnology, has two big approaches, an antibacterial one and a remineralizing one. Silver is recognized to display a powerful toxicity to a large variety of micro-organisms, thus silver-based composites have been widely used in several bactericidal applications.Case report: We present our attempts and results in using silver nanoparticle solutions on a 14-year-old and a 34-year-old patient with dental decays and no previous dental pain. One of the cases was treated with chlorhexidine 2% and the other with Nanocare Plus, as antimicrobial agents. In both cases we recorded decreased values of the bacterial burden in comparison with the initial values.Conclusion: This two-case presentation compared the antibacterial effect of two antibacterial solutions, providing useful information regarding novel therapies for dental caries, but further research in this domain is needed.

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Kariminik, Ashraf, and Mohammad-Mahdi Motaghi. "Evaluation of Antimicrobial susceptibility pattern of Streptococcus mutans isolated from dental plaques to chlorhexidine, nanosil and common antibiotics." International Journal of Life Sciences 9, no. 2 (February 10, 2015): 18–21. http://dx.doi.org/10.3126/ijls.v9i2.12040.

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Streptococcus mutans is one of the most important leading causes of dental diseases worldwide and is considered as one of the main causative agent of dental caries. Increasing resistance of oral pathogens to conventional antibacterial agents has resulted to find alternative therapies to overcome resistance development problems. The aim of this study was to examine susceptibility of Streptococcus mutans isolates to some antibiotics, chlorhexidine and nanosil. The study subjects comprised of caries active individual volunteers attending the outpatient department of different dental college hospitals of Kerman. The saliva sample of 2-5 ml was collected from each individual in sterile capped bottles and were immediately transported to the laboratory and processed for the screening of S. mutans. The specific selective media, Blood agar and Tryptone yeast cysteine media agar were used for the screening and isolation of Streptococcus mutans and incubated anaerobically at 37?C for 48 hrs. Colonies of mutans streptococci were examined under a dissecting microscope and identified by their distinctive colony morphology and biochemical tests .Mutacin production of all isolates were investigated.The isolates were tested for susceptibility to some antibiotics (penicillin, gentamycin, vancomycin, cephalotin), chlorhexidine and nanosil mouthwashes by disc diffusion method. The results showed that the majority of mutacin and non mutacin-producing isolates were more sensitive to the nanosil than antibiotics and chlorhexidine. More extensive research on the use of mouthwashes containing silver nanoparticles is suggested.DOI: http://dx.doi.org/10.3126/ijls.v9i2.12040 International Journal of Life Sciences 9 (2) : 2015; 18-21

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Pereshyvailo, O., V. Holubnycha, and V. Korniienko. "Prospects for the use of silver nanoparticles for the creation of composite dental materials with antimicrobial properties." Reports of Vinnytsia National Medical University 24, no. 1 (May 18, 2020): 125–28. http://dx.doi.org/10.31393/reports-vnmedical-2020-24(1)-24.

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Annotation. Due to the uncontrolled use of antibiotics, the issue of antibiotic resistance has become vitally important. Search the alternative antimicrobials preparation is urgent question. Despite significant achievements in dentistry, the quality of root canals endodontic treatment remains relevant issue. Enterococcus faecalis is one of the ESKAPE group pathogen as well as one of the most common causative agents of intracanal caries. Ag nanoparticles (AgNPs) have shown high efficacy against several polyresistant strains. Therefore, the purpose of our study was to evaluate the possibility of AgNPs using to create composite dental materials with antimicrobial activity. Statistical processing of the obtained results was performed using the software package for statistical data processing Graph Pud Prism 8 with the definition of the Student's criterion. The antibacterial effect of Ag NPs was evaluated against the clinical strain of E. faecalis by determining the minimum inhibitory concentration (serial dilution method) and the minimum bactericidal concentration (direct inoculation of the microorganism from liquid onto solid media). The influence of AgNPs on the multiplication of the bacterial population and on the processes of biofilm formation were investigated. The MIC and MBC were 2.5 µg / ml. Time-kill curve of E. faecalis strain indicates the need for prolonged contact of microorganisms with the nanosilver preparation and reflect a gradual decrease in the number of bacteria in the sample. AgNPs inhibit the formation of biofilms in the early stages and effectively affect 3-days biofilms. The action of the silver nanoparticles at the initiation stage reduced the total volume of the unformed biofilm by 2 times at concentrations of 10 and 20 MICs. The inhibitory effect of silver on the formed 3-day biofilm was dose-dependent and increased with increasing concentration. The obtained results show AgNPs inhibit the growth and reproduction of planktonic and film forms of E. faecalis and can be used to create dental composite with antimicrobial activity.

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Ibrahim, Maria Salem, Isadora Martini Garcia, Taissa Vila, Abdulrahman A. Balhaddad, Fabrício Mezzomo Collares, Michael D. Weir, Hockin H. K. Xu, and Mary Anne S. Melo. "Multifunctional antibacterial dental sealants suppress biofilms derived from children at high risk of caries." Biomaterials Science 8, no. 12 (2020): 3472–84. http://dx.doi.org/10.1039/d0bm00370k.

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Unosson, Erik, Yanling Cai, Xiyuan Jiang, Jesper Lööf, Ken Welch, and Håkan Engqvist. "Antibacterial Properties of Dental Luting Agents: Potential to Hinder the Development of Secondary Caries." International Journal of Dentistry 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/529495.

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A modified direct contact test was used to evaluate the antibacterial properties of four commercially available dental luting agents (RelyX Unicem, Ketac Cem, Ceramir Crown & Bridge and Harvard Cement) and two reference materials (glass-ionomer cement and calcium aluminate cement) compared to a negative-control material (PMMA).Streptococcus mutansbacteria were placed in direct contact with specimens that had been aged for 10 min, 1 day, and 7 days, in order to test the antibacterial properties of the materials. A metabolic assay containing resazurin was used to quantify the amount of viable bacteria remaining after the direct contact tests. The effects of pH and fluoride on bacteria proliferation were also evaluated. Strongest antibacterial properties were found for calcium aluminate cement, followed by Ceramir Crown & Bridge and RelyX Unicem. Ketac Cem, Harvard Cement, and the reference glass-ionomer cement showed bacteria content either higher than or not significantly different from the PMMA control in all instances. pH levels below 6.3 and above 9.0 were found to have negative effects on bacterial proliferation. No correlation between either acidic materials or fluoride release and antibacterial properties could be seen; rather, basic materials showed stronger antibacterial properties.

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Melo, Mary Anne S., Lei Cheng, Michael D. Weir, Ru-Ching Hsia, Lidiany K. A. Rodrigues, and Hockin H. K. Xu. "Novel dental adhesive containing antibacterial agents and calcium phosphate nanoparticles." Journal of Biomedical Materials Research Part B: Applied Biomaterials 101B, no. 4 (December 20, 2012): 620–29. http://dx.doi.org/10.1002/jbm.b.32864.

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Butrón Téllez Girón, Claudia, Juan F. Hernández Sierra, Idania DeAlba‐Montero, María de los A. Urbano Peña, and Facundo Ruiz. "Therapeutic Use of Silver Nanoparticles in the Prevention and Arrest of Dental Caries." Bioinorganic Chemistry and Applications 2020 (August 12, 2020): 1–7. http://dx.doi.org/10.1155/2020/8882930.

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Dental caries is one of the major diseases of the oral cavity affecting humans worldwide. Different alternatives have been used for its control, but its incidence and prevalence are still high. On the other hand, silver has been used for centuries due to its antimicrobial properties. With advances in nanotechnology, the use and research in nanomaterials has increased, recently, and silver nanoparticles have become an essential part of the dental practice, giving materials physical and chemical improvements in their properties, used for their antibacterial capacity preventing and arresting dental caries. The objective of this review was to examine the use of silver nanoparticles, in the treatment of dental caries in the remineralization of teeth hard tissues, as well as the antimicrobial potential, cytotoxicity, and long-term effectiveness.

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Ambulkar, Sonali, Vidya Tale, and Shobha Khilari. "Evaluation of the Antibacterial Potential of Traditional Medicinal Plants against Bacteria Isolated from Dental Caries." Journal of Pure and Applied Microbiology 15, no. 3 (June 26, 2021): 1204–10. http://dx.doi.org/10.22207/jpam.15.3.10.

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Dental caries are one of the leading infectious microbial diseases globally. Streptococcus species are the predominant causative agents for the formation of dental caries. Various antibiotics have been reported for the treatment of dental caries in humans. However, owing to the increasing evidence of microbial resistance, there is a need to develop safe and effective alternative treatments for infections. Traditional medicinal plants and their bioactive products have been explored worldwide for the treatment of various diseases and infections. These plants have great potential for creating novel medications without any side effects. The present study aimed to elucidate the antibacterial potential of medicinal plants against biofilm-forming bacteria from dental caries. Bacteria from dental caries were isolated and identified using 16S rRNA sequencing technique and the predominant bacterial isolates were Streptococcus mutans (MH889143), Enterococcus faecalis (MH793461), Rothia dentocariosa (MH824681), and Streptococcus anginosus (MH889145). The antibacterial potential of seventeen medicinal plants was determined against these bacterial isolates using the agar well diffusion method. The aqueous extracts of Moringa oleifera, Ficus benghalensis, Ficus racemosa, Ficus religiosa, Senegalia catechu, Pistacia integerrima, and Quercus infectoria showed significant inhibition against all bacterial isolates. Pistacia integerrima and Quercus infectoria showed the maximum inhibition. The present study confirmed that traditional medicinal plants could be helpful for the treatment of oral and dental ailments.

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Liu, Zheng, Lihua Zhang, Jincai Wang, Yanping Li, Yiqun Chang, Xiaoling Huang, Jun Duan, Yilong Ai, Xuxin Zeng, and Jialiang Guo. "Virtual Screening and Biological Evaluation of Anti-Biofilm Agents Targeting LuxS in the Quorum Sensing System." Natural Product Communications 16, no. 6 (June 2021): 1934578X2110196. http://dx.doi.org/10.1177/1934578x211019625.

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Biofilm formation is considered as a crucial factor in various oral diseases, such as dental caries. The quorum sensing (QS) signaling system was proved to have a crucial role in the microbial dental plaque biofilm formation of Streptococcus mutans ( S. mutans). LuxS was critical to regulating the QS system and survival of the bacterium, and, therefore, compounds which target LuxS may be a potential therapy for dental caries. The binding activities of 37,170 natural compounds to LuxS were virtually screened in this study. Baicalein and paeonol were chosen for further research of the binding mode and ΔG values with LuxS. Both baicalein and paeonol inhibited the biofilm formation without influence on the growth of S. mutans. Baicalein also distinctly reduced the production of both rhamnolipids and acids. The results provide us with a new approach to combat dental caries instead of the traditional use of antibacterial chemicals.

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Dissertations / Theses on the topic "Dental caries Antibacterial agents. Nanoparticles"

Lam, Chi-wah. "Antibacterial effects of nanoparticles on cariogenic organisms /." View the Table of Contents & Abstract, 2005. http://sunzi.lib.hku.hk/hkuto/record/B31490414.

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林志華 and Chi-wah Lam. "Antibacterial effects of nanoparticles on cariogenic organisms." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B45007743.

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Alshibani, Salah Ramadan. "Screening of Selected Libyan Medicinal Plants for the Synthesis of Metal Nanoparticles and their activity against Streptococcus mutans." University of the Western Cape, 2020. http://hdl.handle.net/11394/7716.

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>Magister Scientiae - MSc
Nanotechnology has emerged as an elementary division of modern science and stemmed directly from green chemistry twelve basic concepts, it receives global attention due to its unique character and ample applications. It also has great potential to mitigate the challenges they face in various fields, especially medical sector. Nanodrugs are increasingly considered as a potential candidate to carry therapeutic agents safely into a targeted compartment in an organ, particular tissue or cell. In this study, twenty (20) Libyan plants were selected and evaluated for their potential to synthesis gold and silver nanoparticles. The screening of the different plant extracts was performed using 96 well plate method at 25 °C and 70 °C. The NPs formation was confirmed and characterized using UV- Vis, DLS, HR-TEM and EDX. A well-defined NPs were obtained at high temperature (70 °C). The Au NPs had an average diameter of 92 nm at 25 °C and 66 nm at 70 °C. The zeta potential values were observed to be negative (-14 to -24) and indicate the stability of the Au NPs. The HR-TEM showed polydispersity, which decreased at higher temperature (70 °C). The stability of Au NPs in nutrient broth prior was conducted as well. All the Au NPs under study showed stability, only minimal changes in the UV-Vis spectra can be observed. Two plant extract viz Pistacia atlantica, Junipers phoenicea showed consistent results and forming stable and smaller NPs compared to others, both of the plant extracts and the corresponding NPs were tested against Streptococcus mutans and showed MIC value ~ 49 g/mL. In case of silver NPs, two plant extracts viz J. phoenicea, Rosmarinus officinalis, showed superior results than the others; both plants produced stable and small Ag NPs. The antibacterial activity against S. mutans demonstrated MIC valus ~ 50 g/mL. The synthesised NPs showed a promising bioactivity for developments of new antibacterial agents against S. mutans strains. Dose-dependent activity was observed for the tested NPs.

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