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Journal articles on the topic 'Dental plaque biofilm'

Author: Grafiati

Published: 3 June 2025

Last updated: 19 July 2025

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1

Sissons, C. H. "Artificial Dental Plaque Biofilm Model Systems." Advances in Dental Research 11, no. 1 (1997): 110–26. http://dx.doi.org/10.1177/08959374970110010201.

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Difficulties with in vivo studies of natural plaque and its complex, heterogeneous structure have led to development of laboratory biofilm plaque model systems. Technologies for their culture are outlined, and the rationale, strengths, and relative uses of two complementary approaches to microbial models with a focus on plaque biodiversity are analyzed. Construction of synthetic consortia biofilms of major plaque species has established a variety of bacterial interactions important in plaque development. In particular, the 'Marsh' nine-species biofilm consortia systems are powerful quasi stead

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DuPont, Gregg A. "Understanding dental plaque; biofilm dynamics." Journal of Veterinary Dentistry 14, no. 3 (1997): 91–94. http://dx.doi.org/10.1177/089875649701400301.

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A biofilm is a well organized community of cooperating microorganisms. Biofilms predictably form in nature, in artificial environments, and on medically implanted prostheses and indwelling venous catheters. They also form on tooth surfaces in the form of dental plaque. The intent of this article is to aid in the understanding of dental plaque by exploring biofilm structure, nature and dynamics. Understanding plaque facilitates its treatment and control.

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Anderson, Sally A., Christopher H. Sissons, Megan J. Coleman, and Lisa Wong. "Application of Carbon Source Utilization Patterns To Measure the Metabolic Similarity of Complex Dental Plaque Biofilm Microcosms." Applied and Environmental Microbiology 68, no. 11 (2002): 5779–83. http://dx.doi.org/10.1128/aem.68.11.5779-5783.2002.

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ABSTRACT Biolog technology was applied to measure the metabolic similarity of plaque biofilm microcosms, which model the complex properties of dental plaque in vivo. The choice of Biolog plate, incubation time, and incubation conditions strongly influenced utilization profiles. For plaque biofilm microcosms, Biolog GP2 plates incubated anaerobically in an H2-free atmosphere gave the clearest profile. To test the application of the Biolog GP2 assay, plaque microcosms were developed under different nutrient conditions in which the frequency of sucrose application was varied. Cluster analysis of

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Koka, Krishna Mohan, Pranitha Pillarisetti, and Manoj Kumar Yasangi. "Dental Plaque Biofilm: Development, Pathogenicity and Analysis." International Journal of Science and Healthcare Research 6, no. 3 (2021): 127–34. http://dx.doi.org/10.52403/ijshr.20210721.

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Biofilms are communities of microorganisms which are found attached to a surface. They develop on both biotic and abiotic surfaces and could act as a source of infection. The development of biofilms is a complex process and it involves several steps such as initial adhesion, reversible binding of bacteria to the solid surface, production of exopolysaccharide matrix, irreversible binding to the surface, maturation of biofilm structure, disintegration and dispersion of organized structure and the formation of new habitats. The biofilm exhibits unique properties of protecting host defences and de

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Akbar, Palwasha, Naima Salahuddin, Zeeshan Ahmad, Syed Zeyad Shah, Fareeha Shah, and Dure Maknoon. "Role of <i>Actinomyces</i> species in oral Biofilm Formation and Dental Plaque-Related Diseases." Innovative Research in Applied, Biological and Chemical Sciences 2, no. 1 (2024): 120–25. http://dx.doi.org/10.62497/irabcs.2024.50.

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Introduction: Actinomyces species play a major role in the development of oral biofilms and disorders associated with dental plaque. The purpose of this study was to look into their interactions, prevalence, and ability to form biofilms in dental plaque. Methodology: Dental plaque samples from 78 participants in a six-month cross-sectional research at KCD Peshawar were examined for Actinomyces species. The microtiter plate test was used to measure the production of biofilms, and statistical analyses were performed to investigate the relationships between Actinomyces presence, plaque severity,

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Jun, Joon-Young, Min-Jeong Jung, In-Hak Jeong, Koji Yamazaki, Yuji Kawai, and Byoung-Mok Kim. "Antimicrobial and Antibiofilm Activities of Sulfated Polysaccharides from Marine Algae against Dental Plaque Bacteria." Marine Drugs 16, no. 9 (2018): 301. http://dx.doi.org/10.3390/md16090301.

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Dental plaque biofilms cause various dental diseases; therefore, inhibiting the growths of the dental plaque bacteria which produce biofilms can be a strategy for preventing dental disease. Certain sulfated polysaccharides from marine algae exert antimicrobial activities against human bacterial pathogens in addition to their physiological benefits. On the basis of these observations, the antimicrobial and antibiofilm activities of sulfated polysaccharides from different marine algae were evaluated against dental plaque bacteria. Among the sulfated polysaccharides, a fucoidan from Fucus vesicul

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Rudney, J. D. "Saliva and Dental Plaque." Advances in Dental Research 14, no. 1 (2000): 29–39. http://dx.doi.org/10.1177/08959374000140010401.

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Dental plaque is being redefined as oral biofilm. Diverse overlapping microbial consortia are present on all oral tissues. Biofilms are structured, displaying features like channels and projections. Constituent species switch back and forth between sessile and planktonic phases. Saliva is the medium for planktonic suspension. Several major functions can be defined for saliva in relation to oral biofilm. It serves as a medium for transporting planktonic bacteria within and between mouths. Bacteria in transit may be vulnerable to negative selection. Salivary agglutinins may prevent reattachment

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Anil, Sukumaran, Shilpa H. Bhandi, Elna P. Chalisserry, Mohammed Jafer, and Jagadish Hosmani. "Chemical Plaque Control Strategies in the Prevention of Biofilm-associated Oral Diseases." Journal of Contemporary Dental Practice 17, no. 4 (2016): 337–43. http://dx.doi.org/10.5005/jp-journals-10024-1851.

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ABSTRACT Dental plaque is a biofilm that forms naturally on the surfaces of exposed teeth and other areas of the oral cavity. It is the primary etiological factor for the most frequently occurring oral diseases, such as dental caries and periodontal diseases. Specific, nonspecific, and ecologic plaque hypothesis explains the causation of dental and associated diseases. Adequate control of biofilm accumulation on teeth has been the cornerstone of prevention of periodontitis and dental caries. Mechanical plaque control is the mainstay for prevention of oral diseases, but it requires patient coop

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9

Guo, Meng, Jianmin Wu, Weilian Hung, et al. "Lactobacillus paracasei ET-22 Suppresses Dental Caries by Regulating Microbiota of Dental Plaques and Inhibiting Biofilm Formation." Nutrients 15, no. 15 (2023): 3316. http://dx.doi.org/10.3390/nu15153316.

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Dental caries is a common and multifactorial biofilm disease that is associated with dietary habits and microbiota. Among the various pathogens inducing caries, S. mutans is the most extensively studied. Promoting oral health with probiotics has gained considerable attention. Lactobacillus paracasei (L. paracasei) strains were reported to modulate the gut microbiota and enhance host resistance to disease. Our previous research has found that L. paracasei ET-22 (ET-22) could inhibit S. mutans biofilms in vitro. However, the preventive effect in vivo and functional mechanism of ET-22 on dental c

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Jakubovics, Nicholas S., Steven D. Goodman, Lauren Mashburn‐Warren, Graham P. Stafford, and Fabian Cieplik. "The dental plaque biofilm matrix." Periodontology 2000 86, no. 1 (2021): 32–56. http://dx.doi.org/10.1111/prd.12361.

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Marsh, P. D., and D. J. Bradshaw. "Dental plaque as a biofilm." Journal of Industrial Microbiology 15, no. 3 (1995): 169–75. http://dx.doi.org/10.1007/bf01569822.

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Overman, Pamela R. "Biofilm: A New View of Plaque." Journal of Contemporary Dental Practice 1, no. 3 (1999): 37–44. http://dx.doi.org/10.5005/jcdp-1-3-37.

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Abstract Dental researchers have attempted to understand the microbial nature of oral diseases over the past 120 years. Their view of plaque and its constituent microorganisms has shifted from a specific plaque hypothesis to a non-specific plaque hypothesis and back again to a theory of specific periodontal pathogens in plaque. Changes in the way plaque and its microorganisms are viewed affect the strategies used to prevent and control periodontal diseases. In recent years, dental researchers have begun to view plaque as a biofilm. This shifting view of plaque has important implications for fu

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Chumakova, Y., and V. Antoshchuk. "Biofilm visualization as a component of the procedure of individual and professional tooth brushing. (Literature Review)." SUCHASNA STOMATOLOHIYA 116, no. 5 (2023): 12. https://doi.org/10.33295/1992-576x-2023-5-12.

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Introduction. Dental plaque is a structured microbial biofilm on the surface of tooth enamel, which is usually transparent and practically invisible to the naked eye. Therefore, special dyeing solutions or tablets, the so-called "disclosing agents" or "plaque indicators", are used for visualization and identification of biofilm. They make it possible to clearly see the presence of plaque, to determine its location and thickness on various surfaces of the tooth, including in hard-to-reach areas. Purpose: based on the analysis of scientific articles, to determine the composition, properties of v

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Thenappan, Paarvathi, R. Vijayalakshmi, C. Burnice Nalina Kumari, Nikita Ravi, Surthi Senthil, and Jaideep Mahendra. "Biofilm on Dental Implants - An Overview." International Journal of Current Research and Review 15, no. 12 (2023): 08–11. http://dx.doi.org/10.31782/ijcrr.2023.151203.

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Dental plaque may be described as structured resilient yellow, grayish substance adhering to the tooth surface. The mineralized dental plaque is referred to as dental calculus. Bacteria within the biofilm are usually in understanding with the host immune response, disease occurs when this harmony is disrupted. These biofilm bacteria contribute around 80% of the total bacterial infection. The important biofilm related infection in the oral cavity are dental caries and periodontitis. This article will enlighten your knowledge on history, structure, classification, formation, composition, diagnos

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Kryvanych, V., V. Kuligina, A. Yurzhenko, and Peter Dzhupa. "Characteristics of the microbiological profile and dental biofilm in the aspect of age, its influence on the dental and periodontal status of the patient." SUCHASNA STOMATOLOHIYA 117, no. 6 (2023): 22. http://dx.doi.org/10.33295/1992-576x-2023-6-22.

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Summary. The oral cavity is a complex ecological system in which external factors (biological, individual, social) are closely interconnected with internal factors (tissues of the periodontal complex, dentin metabolites, microbial biofilm, local immune protection, epithelium of the oral cavity) and are in dynamic balance. The aim of the study. To investigate the level and trends of the development of scientific knowledge about oral biofilm and its management, leaving. Materials and methods. 24 еnglish-language and 37 domestic literary sources were processed. Conclusions. A detailed analysis of

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Cao, Li, Junling Wu, Qiang Zhang, et al. "Novel Protein-Repellent and Antibacterial Resins and Cements to Inhibit Lesions and Protect Teeth." International Journal of Polymer Science 2019 (July 2, 2019): 1–11. http://dx.doi.org/10.1155/2019/5602904.

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Orthodontic treatment is increasingly popular as people worldwide seek esthetics and better quality of life. In orthodontic treatment, complex appliances and retainers are placed in the patients’ mouths for at least one year, which often lead to biofilm plaque accumulation. This in turn increases the caries-inducing bacteria, decreases the pH of the retained plaque on an enamel surface, and causes white spot lesions (WSLs) in enamel. This article reviews the cutting-edge research on a new class of bioactive and therapeutic dental resins, cements, and adhesives that can inhibit biofilms and pro

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Rath, Shakti, Sourav Chandra Bidyasagar Bal, and Debasmita Dubey. "Oral Biofilm: Development Mechanism, Multidrug Resistance, and Their Effective Management with Novel Techniques." Rambam Maimonides Medical Journal 12, no. 1 (2021): e0004. http://dx.doi.org/10.5041/rmmj.10428.

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Biofilms are formed by the congregation of one or more types of microorganisms that can grow on a firm surface. Dental plaque is one of the most commonly forming biofilms in the oral cavity and appears as a slimy layer on the surface of the teeth. In general, the formation is slow, but biofilms are very adaptive to the changing environment, and a mature biofilm can cause many health-related problems in humans. These biofilms remain unaffected by antibiotics as they do not allow the penetration of antibiotics. Moreover, the increased level of virulence and antibiotic resistance of microorganism

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Kozak, Urszula, Agnieszka Lasota, and Renata Chałas. "Changes in Distribution of Dental Biofilm after Insertion of Fixed Orthodontic Appliances." Journal of Clinical Medicine 10, no. 23 (2021): 5638. http://dx.doi.org/10.3390/jcm10235638.

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Good oral hygiene is an important factor in oral and general health, especially in orthodontic patients, because fixed appliances might impede effective oral hygiene and thus increase the risks of tooth decay, periodontal disease and general health complications. This study investigated the impact of fixed orthodontic appliances on the distribution of dental biofilm in teenagers. Supragingival plaque was assessed at T0, T1 and T2. The distribution of the biofilm was analyzed. Approximal Plaque Index (API) and Bonded Bracket Index (BBI) were used to measure the presence of dental plaque. After

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Ambade, Sonia, Neelima Deshpande, and Pragati Abhyankar. "Effect of Lemongrass Essential Oil based Mouthwash against Microflora Associated with Dental Plaque." Journal of Pure and Applied Microbiology 16, no. 1 (2022): 174–81. http://dx.doi.org/10.22207/jpam.16.1.06.

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Mouthwash is one of the most convenient and effective method employed for dental plaque management. The aim of the undertaken study was to establish the antimicrobial and anti-biofilm properties of lemongrass essential oil (LGEO) based mouthwash on microbial flora from dental plaque and also check cytotoxicity of mouthwash formulation. Five main colonizers of dental plaque representing dental microflora and three different bacterial species mainly responsible for the formation of biofilm were selected in this study. LGEO based mouthwash was developed and its stability was also determined. The

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Marsh, P. D. "Dental Plaque as a Microbial Biofilm." Caries Research 38, no. 3 (2004): 204–11. http://dx.doi.org/10.1159/000077756.

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Xie, Hua, Guy S. Cook, J. William Costerton, Greg Bruce, Timothy M. Rose, and Richard J. Lamont. "Intergeneric Communication in Dental Plaque Biofilms." Journal of Bacteriology 182, no. 24 (2000): 7067–69. http://dx.doi.org/10.1128/jb.182.24.7067-7069.2000.

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ABSTRACT Dental plaque is a complex biofilm that accretes in a series of discrete steps proceeding from a gram-positive streptococcus-rich biofilm to a structure rich in gram-negative anaerobes. This study investigated information flow between two unrelated plaque bacteria,Streptococcus cristatus and Porphyromonas gingivalis. A surface protein of S. cristatus caused repression of the P. gingivalisfimbrial gene (fimA), as determined by a chromosomalfimA promoter-lacZ reporter construct and by reverse transcription-PCR. Signaling activity was associated with a 59-kDa surface protein of S. crista

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Ambade, S. V., N. M. Deshpande, S. S. Kale, and V. N. Ambade. "Antimicrobial and Antibiofilm Activity of Citral and its Derivative against Microflora from Dental Plaque." Asian Journal of Organic & Medicinal Chemistry 5, no. 2 (2020): 120–26. http://dx.doi.org/10.14233/ajomc.2020.ajomc-p259.

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Dental biofilms inhabit the oral cavity in form of dental plaque which then causes dental caries and periodontal diseases worldwide. Lemon grass essential oil (LGEO) has been reported to exhibit antimicrobial and antibiofilm activity against. This study represents the potential of citral and derivatives as antimicrobial and antibiofilm agent against dental microflora. Three bacterial species chiefly responsible for biofilm formation, and five prime colonizer of dental plaque were selected to represent dental microflora. Citral and its derivative viz. citral semicarbazone, exhibited antimicrobi

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Del Rey, Yumi C., Pernille D. Rikvold, Karina K. Johnsen, and Sebastian Schlafer. "Clinical Trial Data on the Mechanical Removal of 14-Day-Old Dental Plaque Using Accelerated Micro-Droplets of Air and Water (Airfloss)." Data 8, no. 4 (2023): 70. http://dx.doi.org/10.3390/data8040070.

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Novel strategies to combat dental biofilms aim at reducing biofilm stability with the ultimate goal of facilitating mechanical cleaning. To test the stability of dental biofilms, they need to be subjected to a defined mechanical stress. Here, we employed an oral care device (Airfloss) that emits microbursts of compressed air and water to apply a defined mechanical shear to 14-day-old dental plaque in 20 healthy participants with no signs of oral diseases (clinical trial no. NCT05082103). Exclusion criteria included pregnant or nursing women, users of oral prostheses, retainers or orthodontic a

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Chismirina, Santi, Evlin Vernanda, Deffan Dericco, Suzanna Sungkar, Sri Rezeki, and Shahida Mohd Said. "Quantitative and qualitative analysis of goat's milk antibiofilm against Streptococcus mutans and Candida albicans: a laboratory experiment." Padjadjaran Journal of Dentistry 37, no. 2 (2025): 131–41. https://doi.org/10.24198/pjd.vol37no2.61674.

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Streptococcus mutans and Candida albicans interact in dental plaque biofilm to form a synergistic caries process. As a result, preventing tooth cavities necessitates disrupting the interaction between these two bacteria. This can be accomplished by giving anti-biofilm substances such as goat's milk, which contains lactoferrin, lactoperoxidase, and lysozyme. Candida albicans in dental biofilms promotes more violent caries than biofilms generated only by Streptococcus mutants. This study aimed to analyze the antibiofilm of goat's milk against Streptococcus mutans and Candida albicans biofilm mas

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Rostami, N., R. C. Shields, S. A. Yassin, et al. "A Critical Role for Extracellular DNA in Dental Plaque Formation." Journal of Dental Research 96, no. 2 (2016): 208–16. http://dx.doi.org/10.1177/0022034516675849.

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Extracellular DNA (eDNA) has been identified in the matrix of many different monospecies biofilms in vitro, including some of those produced by oral bacteria. In many cases, eDNA stabilizes the structure of monospecies biofilms. Here, the authors aimed to determine whether eDNA is an important component of natural, mixed-species oral biofilms, such as plaque on natural teeth or dental implants. To visualize eDNA in oral biofilms, approaches for fluorescently stained eDNA with either anti-DNA antibodies or an ultrasensitive cell-impermeant dye, YOYO-1, were first developed using Enterococcus fa

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Korenaga, Arisu, Toshiki Miyaoka, Harumi Asami, et al. "Synergetic inhibitory effect of isopropyl methylphenol-based agents on biofilm formation by Streptococcus mutans." PLOS ONE 19, no. 9 (2024): e0310926. http://dx.doi.org/10.1371/journal.pone.0310926.

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Dental caries and periodontitis are the most common oral diseases in humans and the main causes of tooth loss. Streptococcus mutans is primarily responsible for dental caries and dental plaque, which are triggered by biofilm formation on the tooth surface. In this study, biofilm inhibition by 4-isopropyl-3-methylphenol (IPMP)-based agents, consisting of IPMP and polyoxyethylene-hydrogenated castor oil (POEHCO), was investigated in vitro. Notably, the use of POEHCO in addition to IPMP inhibited S. mutans biofilms more drastically than IPMP alone. Moreover, the effects of IPMP on the expression

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Segura, Elda P., Luis Méndez, Eréndira Márquez, et al. "Effect of Carya illinoinensis, Quercus rubra and Smilax glyciphylla extracts, pectin, and papain on the dental biofilm microorganisms." Journal of Pharmacy & Pharmacognosy Research 3, no. 1 (2015): 118–29. http://dx.doi.org/10.56499/jppres15.059_3.5.118.

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Context: Dental caries is an infectious disease resulting in destruction of tooth structure by acid-forming bacteria found in dental plaque and intraoral biofilms, which are made up of mixed-species microbial communities, and their uncontrolled outgrowth can lead to oral disease. Aims: To analyze new biological materials (papain, pectin, three plant extracts and their combinations), for prevention, control, and treatment of oral bacteria and biofilm in vitro and in vivo. Methods: Papain, citric pectin, extracts of Carya illinoinensis, Quercus rubra, and Smilax glyciphylla were applied. In vitr

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K L Tsang, Annetta, Saso Ivanovski, and Philip S Bird. "Caries and periodontal disease: Two diseases, one biofilm." Microbiology Australia 26, no. 3 (2005): 110. http://dx.doi.org/10.1071/ma05110.

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Dental plaque, a natural oral biofilm is involved in the aetiology of dental caries and periodontal disease. Despite decades of research, the microbiology, aetiology and pathogenesis of these diseases remain controversial. A number of factors interplay in these diseases, the indigenous microbes that inhabit the oral cavity, diet, host susceptibility and time. The ?Non-Specific Plaque Hypothesis? (NSPH) was proposed where the overall mass of plaque interacted with the host and caused disease. An alternative view was the ?Specific Plaque Hypothesis? (SPH) where, among the diverse microbial commu

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Hertiani, Triana, Sylvia Utami Tunjung Pratiwi, Iramie Duma Kencana Irianto, and Aini Febriana. "Kaempferia galanga L. Rhizome As a Potential Dental Plaque Preventive Agent." Indonesian Journal of Cancer Chemoprevention 1, no. 1 (2010): 19. http://dx.doi.org/10.14499/indonesianjcanchemoprev1iss1pp19-25.

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Dental plaque prevention can be achieved by inhibition of mouth cavity microbes to built biofilm. Kaempferia galanga rhizome has been known as a potential antibacterial agent. This research aimed to reveal the potency of Kaempferia galanga extract and essential oil as anti plaque active agents, based on their in vitro inhibitory activity against the planktonic growth and biofilm of Streptococcus mutans ATCC 21752. Kaempferia galanga extract was obtained by defatting dried-pulverized samples in petroleum ether prior to immersion in 70% ethanol. The fresh rhizome was steam-hydro distilled for 6

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Kowalczyk, Kacper, Débora C. Coraça-Huber, Walter Wille-Kollmar, Michael Berktold, and Markus Nagl. "Activity of N-Chlorotaurine against Periodontal Pathogens." International Journal of Molecular Sciences 25, no. 15 (2024): 8357. http://dx.doi.org/10.3390/ijms25158357.

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Dental plaque bacteria play an important role in the pathogenicity of periodontitis and peri-implantitis. Therefore, antimicrobial agents are one means of treatment. N-chlorotaurine (NCT) as an endogenous well-tolerated topical antiseptic could be of advantage for this purpose. Accordingly, its microbicidal activity against some dental plaque bacteria was investigated at therapeutic concentrations in vitro. In quantitative killing assays, the activity of NCT against planktonic bacteria and against biofilms grown for 48 h on implantation screws was tested. Electron microscopy was used to demons

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Biradar, Baswaraj, and Prapulla Devi. "Quorum Sensing in Plaque Biofilms: Challenges and Future Prospects." Journal of Contemporary Dental Practice 12, no. 6 (2011): 479–85. http://dx.doi.org/10.5005/jp-journals-10024-1080.

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ABSTRACT Aim This review intends to provide a brief overview regarding quorum sensing among bacteria in biofilms and also attempts to throw light on the new research focusing on interference with the quorum sensing. Background Dental plaque is an example of microbial biofilm leading to periodontal disease and dental caries. Quorum sensing is widely employed by a variety of gram-positive and gram-negative bacterial species to coordinate various activities in biofilms. Quorum-sensing-interfering compounds have either a positive or a negative effect on the expression of bacterial phenotypes regul

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Pisarska, Aleksandra, Renata Wolinowska, Joanna Rudnicka, and Ewa Iwanicka-Grzegorek. "Characteristics of Clinical Isolates of Streptococcus mutans." Applied Sciences 12, no. 9 (2022): 4579. http://dx.doi.org/10.3390/app12094579.

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Dental caries is an infectious disease which remains a significant health problem all over the world. The purpose of the study was to characterise a collection of 60 clinical isolates of S. mutans from adults’ and children’s dental plaque (natural biofilm). The paper describes the process of isolation, identification, analysis of biofilm formation and collection testing for the presence of 13 two-component systems (TCS) identified earlier in reference strain ATCC 700610 (UA159). In the case of S. mutans strains, plaque formation is specifically influenced by binary systems. All isolated strain

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Yarashova, Shaxrizoda Ilyosovna, Nikita Sergeyevich Li, Bobur Baxodirovich Abdusalomov, and Imronbek Rustamovich Ismailov. "PATHOGENESIS OF PERIODONTAL DISEASES CAUSED BY DENTAL PLAQUE." Multidisciplinary Journal of Science and Technology 4, no. 4 (2024): 273–77. https://doi.org/10.5281/zenodo.11044369.

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Periodontal diseases, such as gingivitis and periodontitis, are primarily driven by the accumulation of dental plaque, a complex microbial biofilm forming on teeth and gums. This article explores the pathogenesis of periodontal diseases caused by dental plaque, detailing the stages of biofilm formation, the role of periodontal pathogens, and the host immune response leading to chronic inflammation. The progression from gingivitis to periodontitis involves periodontal pocket formation, tissue destruction, and alveolar bone loss. The systemic impact of periodontal diseases is discussed, highligh

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Falsetta, Megan L., Marlise I. Klein, Punsiri M. Colonne, et al. "Symbiotic Relationship between Streptococcus mutans and Candida albicans Synergizes Virulence of Plaque BiofilmsIn Vivo." Infection and Immunity 82, no. 5 (2014): 1968–81. http://dx.doi.org/10.1128/iai.00087-14.

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ABSTRACTStreptococcus mutansis often cited as the main bacterial pathogen in dental caries, particularly in early-childhood caries (ECC).S. mutansmay not act alone;Candida albicanscells are frequently detected along with heavy infection byS. mutansin plaque biofilms from ECC-affected children. It remains to be elucidated whether this association is involved in the enhancement of biofilm virulence. We showed that the ability of these organisms together to form biofilms is enhancedin vitroandin vivo. The presence ofC. albicansaugments the production of exopolysaccharides (EPS), such that cospeci

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Zarif, Maria Elena, Sașa Alexandra Yehia, Bogdan Biță, et al. "Atmospheric Pressure Plasma Activation of Hydroxyapatite to Improve Fluoride Incorporation and Modulate Bacterial Biofilm." International Journal of Molecular Sciences 22, no. 23 (2021): 13103. http://dx.doi.org/10.3390/ijms222313103.

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Despite the technological progress of the last decade, dental caries is still the most frequent oral health threat in children and adults alike. Such a condition has multiple triggers and is caused mainly by enamel degradation under the acidic attack of microbial cells, which compose the biofilm of the dental plaque. The biofilm of the dental plaque is a multispecific microbial consortium that periodically develops on mammalian teeth. It can be partially removed through mechanical forces by individual brushing or in specialized oral care facilities. Inhibition of microbial attachment and biofi

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Wu, Christine D., Ellen Huang, Wei Li, Mark White, Shawn Jung, and Qian Xie. "Beverages Containing Plant-Derived Polyphenols Inhibit Growth and Biofilm Formation of Streptococcus mutans and Children’s Supragingival Plaque Bacteria." Beverages 7, no. 3 (2021): 43. http://dx.doi.org/10.3390/beverages7030043.

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Objectives: Polyphenols in edible berries and tea plant (Camellia sinensis) suppressed virulence factors of oral pathogens. We investigated if the commercially marketed plant polyphenols-containing beverages inhibited growth and biofilm formation of Streptococcus mutans and children’s dental plaque. Methods: Supragingival plaque collected from 16 children (7–11 years) were suspended in TSB for testing. Test beverages included 26 marketed packaged teas, ready-to-drink bottled raspberry flavored teas and cranberry juice cocktails with and without added sugars. Their effects on in vitro growth an

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Sneha Kannan, Lakshmi T, and Ganesh Lakshmanan. "Awareness on Mechanical and Chemical Plaque Control in Children- A Survey." International Journal of Research in Pharmaceutical Sciences 11, SPL3 (2020): 1605–10. http://dx.doi.org/10.26452/ijrps.v11ispl3.3483.

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Periodontal infections (gum disease and periodontitis) are viewed as incendiary maladies of microbiological starting points. Their most significant hazard factor is the amassing of a plaque biofilm at and beneath the gingival edge, which is then connected with an improper and ruinous host fiery insusceptible reaction Plaque control is the day by day expulsion of dental plaque, oral biofilm and furthermore counteraction of their collection on the teeth and different pieces of the oral pit. Mechanical plaque control is a viable strategy to dispose of gathering in the oral cavity. With opportunit

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Jain, Ravindra Kumar, Mathew Thomas Maliael, and Sankar Ganesh Pitchaipillai. "Evaluation of Antibacterial and Antibiofilm Activity of Cucurbita Maxima Leaf Extract Against Streptococcus Mutans Isolated from Orthodontic Patients." International Journal of Orthodontic Rehabilitation 14, no. 3 (2023): 11–19. http://dx.doi.org/10.56501/intjorthodrehabil.v14i3.763.

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Aim The aim of this investigation was to evaluate the antimicrobial activity and anti-biofilm activity of Cucurbita Maxima leaf extract on Streptococcus mutans isolated from dental plaque of subjects undergoing orthodontic treatment. Methodology Dental plaque samples were collected from out patients undergoing orthodontic treatment. From the plaque samples Biochemical Characterisation of Streptococcus mutans then Collection of Medicinal Plants was done followed by Preparation of Solvent Extract and stock Solution. Evaluation of Minimum Inhibitory Concentration (MIC) of the plant extract and Bi

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Kardaras, Georgios, Marius Boariu, Vadym Varlamov, et al. "Three-Dimensional Planimetry Assessment of Dental Plaque-Covered Area Reduction after Rinsing with 0.2% Sodium Hypochlorite Solution as Part of a Guided Biofilm Therapy® Protocol—Pilot Longitudinal Study." Biomedicines 12, no. 10 (2024): 2326. http://dx.doi.org/10.3390/biomedicines12102326.

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Background/Objectives: Less often employed as a rinsing solution for controlling oral biofilms, NaOCL was used in oral rinses at various concentrations in steps 1 and 4 of periodontal therapy. The aim of this study was to quantitatively evaluate the biofilm-disruptive properties of a 0.2% NaOCl solution in standardized oral rinses using dedicated plaque-disclosing agents and 3D scanning methods in patients undergoing the regular Guided Biofilm Therapy® protocol. Methods: Eight patients with at least 20 teeth present evenly distributed between the two arches were included. After 24 h of refrain

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Motallaei, Mohammad Nima, Mohsen Yazdanian, Hamid Tebyanian, et al. "The Current Strategies in Controlling Oral Diseases by Herbal and Chemical Materials." Evidence-Based Complementary and Alternative Medicine 2021 (August 21, 2021): 1–22. http://dx.doi.org/10.1155/2021/3423001.

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Dental plaque is a biofilm composed of complex microbial communities. It is the main cause of major dental diseases such as caries and periodontal diseases. In a healthy state, there is a delicate balance between the dental biofilm and host tissues. Nevertheless, due to the oral cavity changes, this biofilm can become pathogenic. The pathogenic biofilm shifts the balance from demineralization-remineralization to demineralization and results in dental caries. Dentists should consider caries as a result of biological processes of dental plaque and seek treatments for the etiologic factors, not m

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Sharma, Shivani, Stacey Lavender, JungReem Woo, et al. "Nanoscale characterization of effect of l-arginine on Streptococcus mutans biofilm adhesion by atomic force microscopy." Microbiology 160, no. 7 (2014): 1466–73. http://dx.doi.org/10.1099/mic.0.075267-0.

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A major aetiological factor of dental caries is the pathology of the dental plaque biofilms. The amino acid l-arginine (Arg) is found naturally in saliva as a free molecule or as a part of salivary peptides and proteins. Plaque bacteria metabolize Arg to produce alkali and neutralize glycolytic acids, promoting a less cariogenous oral microbiome. Here, we explored an alternative and complementary mechanism of action of Arg using atomic force microscopy. The nanomechanical properties of Streptococcus mutans biofilm extracellular matrix were characterized under physiological buffer conditions. W

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Hwang, Geelsu, Markus B. Blatz, Mark S. Wolff, and Liviu Steier. "Diagnosis of Biofilm-Associated Peri-Implant Disease Using a Fluorescence-Based Approach." Dentistry Journal 9, no. 3 (2021): 24. http://dx.doi.org/10.3390/dj9030024.

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Dental implants have become a routine component of daily dental practice and the demand for dental implants is expected to increase significantly in the future. Despite the high success rates of dental implants, failures do occur, resulting in discomfort, rampant destruction of the oral health, or painful and costly surgical replacement of a failed implant. Peri-implant diseases are inflammatory conditions affecting the soft/hard tissues surrounding a functional dental implant. Plenty of experimental evidence indicates that the accumulation of dental plaque at the soft tissue–implant interface

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Nikitkova, Anna E., Elaine M. Haase та Frank A. Scannapieco. "Taking the Starch out of Oral Biofilm Formation: Molecular Basis and Functional Significance of Salivary α-Amylase Binding to Oral Streptococci". Applied and Environmental Microbiology 79, № 2 (2012): 416–23. http://dx.doi.org/10.1128/aem.02581-12.

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ABSTRACTα-Amylase-binding streptococci (ABS) are a heterogeneous group of commensal oral bacterial species that comprise a significant proportion of dental plaque microfloras. Salivary α-amylase, one of the most abundant proteins in human saliva, binds to the surface of these bacteria via specific surface-exposed α-amylase-binding proteins. The functional significance of α-amylase-binding proteins in oral colonization by streptococci is important for understanding how salivary components influence oral biofilm formation by these important dental plaque species. This review summarizes the resul

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Ruhl, Stefan, Andreas Eidt, Holger Melzl, Udo Reischl, and John O. Cisar. "Probing of Microbial Biofilm Communities for Coadhesion Partners." Applied and Environmental Microbiology 80, no. 21 (2014): 6583–90. http://dx.doi.org/10.1128/aem.01826-14.

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ABSTRACTInvestigations of interbacterial adhesion in dental plaque development are currently limited by the lack of a convenient assay to screen the multitude of species present in oral biofilms. To overcome this limitation, we developed a solid-phase fluorescence-based screening method to detect and identify coadhesive partner organisms in mixed-species biofilms. The applicability of this method was demonstrated using coaggregating strains of type 2 fimbrial adhesin-bearing actinomyces and receptor polysaccharide (RPS)-bearing streptococci. Specific adhesin/receptor-mediated coadhesion was de

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Melo, Mary, Michael Weir, Vanara Passos, et al. "Human In Situ Study of the effect of Bis(2-Methacryloyloxyethyl) Dimethylammonium Bromide Immobilized in Dental Composite on Controlling Mature Cariogenic Biofilm." International Journal of Molecular Sciences 19, no. 11 (2018): 3443. http://dx.doi.org/10.3390/ijms19113443.

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Cariogenic oral biofilms cause recurrent dental caries around composite restorations, resulting in unprosperous oral health and expensive restorative treatment. Quaternary ammonium monomers that can be copolymerized with dental resin systems have been explored for the modulation of dental plaque biofilm growth over dental composite surfaces. Here, for the first time, we investigated the effect of bis(2-methacryloyloxyethyl) dimethylammonium bromide (QADM) on human overlying mature oral biofilms grown intra-orally in human participants for 7–14 days. Seventeen volunteers wore palatal devices co

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Velliyagounder, Kabilan, Anil Ardeshna, Julia Koo, Mathew Rhee, and Daniel H. Fine. "The Microflora Diversity and Profiles in Dental Plaque Biofilms on Brackets and Tooth Surfaces of Orthodontic Patients." Journal of Indian Orthodontic Society 53, no. 3 (2019): 183–88. http://dx.doi.org/10.1177/0301574219851160.

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Objective: Fixed orthodontic appliances may influence the oral environment through accumulation of plaque, decreased plaque pH, and increased gingival inflammation. These changes in the oral cavity can potentially lead to periodontal disease, demineralization, and other infectious diseases. Materials and Methods: To investigate the changes in biofilm throughout the initial 2 weeks, we placed a stainless steel bracket on the upper second premolar and collected plaque samples on the bracket and on the tooth surface at different time points (0, 24, 48 h and 1 and 2 weeks) and plated on tryptic so

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Zhu, Xiao, Zhejun Wang, and Yining Wang. "Formation of Dental Plaque Biofilm on Different Titanium Surfaces and Evaluate Antimicrobial Effects of Mouthrinses on Dental Plaque Biofilm." Journal of Wuhan University of Technology-Mater. Sci. Ed. 34, no. 2 (2019): 465–71. http://dx.doi.org/10.1007/s11595-019-2075-1.

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Al-Ahmad, Ali, Axel Wunder, Thorsten Mathias Auschill, et al. "The in vivo dynamics of Streptococcus spp., Actinomyces naeslundii, Fusobacterium nucleatum and Veillonella spp. in dental plaque biofilm as analysed by five-colour multiplex fluorescence in situ hybridization." Journal of Medical Microbiology 56, no. 5 (2007): 681–87. http://dx.doi.org/10.1099/jmm.0.47094-0.

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The formation and composition of dental plaque biofilm in vivo are important factors which influence the development of gingivitis, caries and periodontitis. Studying dental plaque biofilm in in vitro models can cause an oversimplification of the real conditions in the oral cavity. In this study, bovine enamel slabs were fixed in an individual acrylic appliance in situ to quantify dental plaque formation and composition using multiplex fluorescence in situ hybridization (FISH) and confocal laser scanning microscopy. Each of the five oligonucleotide probes used for FISH was specific for either

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Paramonova, E., O. J. Kalmykowa, H. C. van der Mei, H. J. Busscher, and P. K. Sharma. "Impact of Hydrodynamics on Oral Biofilm Strength." Journal of Dental Research 88, no. 10 (2009): 922–26. http://dx.doi.org/10.1177/0022034509344569.

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Mechanical removal of oral biofilms is ubiquitously accepted as the best way to prevent caries and periodontal diseases. Removal effectiveness strongly depends on biofilm strength. To investigate the influence of hydrodynamics on oral biofilm strength, we grew single- and multi-species biofilms of Streptococcus oralis J22, Actinomyces naeslundii TV14-J1, and full dental plaque at shear rates ranging from 0.1 to 50 1/sec and measured their compressive strength. Subsequently, biofilm architecture was evaluated by confocal laser scanning microscopy. Multi-species biofilms were stronger than singl

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Pradhan, Yashashree, Hari Prasad Devkota, and Ahmad Ali. "Potential Role of Medicinal Plants and their Phytochemicals against Plaque forming Oral Microbiota." Biosciences Biotechnology Research Asia 21, no. 2 (2024): 371–89. http://dx.doi.org/10.13005/bbra/3232.

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Dental plaque, a type of biofilm formed on the tooth surface, is one of the most common dental problems suffered by many individuals all over the world. Various mechanical methods are used to remove plaque and certain chemical agents are used for prevention from dental plaque formation. Though these agents have fast action, long term use of synthetic agents may cause certain side effects. People around the world have been using medicinal plants for oral health care from hundreds of years. Some of such plants that are used in the prevention of dental plaques are Ocimum basilicum, Azadirachta in

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