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Journal articles on the topic 'Dental pulp - Anatomy'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 February 2022

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1

Lee, Sheng-Yang, Guo-Wei Huang, Jau-Nan Shiung, et al. "Magnetic Cryopreservation for Dental Pulp Stem Cells." Cells Tissues Organs 196, no. 1 (2012): 23–33. http://dx.doi.org/10.1159/000331247.

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2

Marchetti, C., P. Poggi, A. Calligaro, and A. Casasco. "Lymphatic Vessels in the Healthy Human Dental Pulp." Cells Tissues Organs 140, no. 4 (1991): 329–34. http://dx.doi.org/10.1159/000147078.

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3

Takamori, Yasuhiko, Hironobu Suzuki, Kuniko Nakakura-Ohshima, et al. "Capacity of Dental Pulp Differentiation in Mouse Molars as Demonstrated by Allogenic Tooth Transplantation." Journal of Histochemistry & Cytochemistry 56, no. 12 (2008): 1075–86. http://dx.doi.org/10.1369/jhc.2008.951558.

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Dental pulp elaborates both bone and dentin under pathological conditions such as tooth replantation/transplantation. This study aims to clarify the capability of dental pulp to elaborate bone tissue in addition to dentin by allogenic tooth transplantation using immunohistochemistry and histochemistry. After extraction of the molars of 3-week-old mice, the roots and pulp floor were resected and immediately allografted into the sublingual region in a littermate. In addition, we studied the contribution of donor and host cells to the regenerated pulp tissue using a combination of allogenic tooth

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4

Bishop, M. A., and M. Malhotra. "An investigation of lymphatic vessels in the feline dental pulp." American Journal of Anatomy 187, no. 3 (1990): 247–53. http://dx.doi.org/10.1002/aja.1001870304.

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5

Ida-Yonemochi, Hiroko, Kazufumi Ohshiro, Wael Swelam, Hamdy Metwaly, and Takashi Saku. "Perlecan, a Basement Membrane-type Heparan Sulfate Proteoglycan, in the Enamel Organ: Its Intraepithelial Localization in the Stellate Reticulum." Journal of Histochemistry & Cytochemistry 53, no. 6 (2005): 763–72. http://dx.doi.org/10.1369/jhc.4a6479.2005.

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The localization and biosynthesis of perlecan, a basement membrane-type heparan sulfate proteoglycan, were studied in developing tooth germs by using murine molars in neonatal and postnatal stages and primary cultured cells of the enamel organ and dental papilla to demonstrate the role of perlecan in normal odontogenesis. Perlecan was immunolocalized mainly in the intercellular spaces of the enamel organ as well as in the dental papilla/pulp or in the dental follicle. By in situ hybridization, mRNA signals for perlecan core protein were intensely demonstrated in the cytoplasm of stellate retic

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6

Casasco, A., A. Calligaro, M. Casasco, et al. "Peptidergic nerves in human dental pulp." Histochemistry 95, no. 2 (1990): 115–21. http://dx.doi.org/10.1007/bf00266583.

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7

Stuepp, Rubia Teodoro, Priscilla Barros Delben, Filipe Modolo, Andrea Gonçalves Trentin, Ricardo Castilho Garcez, and Michelle Tillmann Biz. "Human Dental Pulp Stem Cells in Rat Mandibular Bone Defects." Cells Tissues Organs 207, no. 3-4 (2019): 138–48. http://dx.doi.org/10.1159/000502513.

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This study aimed to evaluate the use of human dental pulp stem cells (hDPSCs) in non-critical-sized mandibular bone defects in rats. hDPSCs from permanent teeth were isolated and engrafted in mandibular bone defects in rats for 7, 14, and 28 days; bone defects without cells formed the control group. Samples were evaluated by scanning electron microscopy (SEM), light microscopy (hematoxylin and eosin staining), and the regeneration area was measured by the Image J program. Before surgery procedures, the human dental pulp cells were characterized as dental pulp stem cells: fusiform morphology, p

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8

Oehmke, Matthias J., Erich Knolle, and Hans-Joachim Oehmke. "Lymph drainage in the human dental pulp." Microscopy Research and Technique 62, no. 3 (2003): 187–91. http://dx.doi.org/10.1002/jemt.10378.

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9

Waddington, Rachel J., Sarah J. Youde, Chi P. Lee, and Alastair J. Sloan. "Isolation of Distinct Progenitor Stem Cell Populations from Dental Pulp." Cells Tissues Organs 189, no. 1-4 (2008): 268–74. http://dx.doi.org/10.1159/000151447.

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10

Lu, Changming, Samuel Huguley, Chun Cui, et al. "Effects of FGFR Signaling on Cell Proliferation and Differentiation of Apert Dental Cells." Cells Tissues Organs 201, no. 1 (2015): 26–37. http://dx.doi.org/10.1159/000441349.

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The Apert syndrome is a rare congenital disorder most often arising from S252W or P253R mutations in fibroblast growth factor receptor (FGFR2). Numerous studies have focused on the regulatory role of Apert FGFR2 signaling in bone formation, whereas its functional role in tooth development is largely unknown. To investigate the role of FGFR signaling in cell proliferation and odontogenic differentiation of human dental cells in vitro, we isolated dental pulp and enamel organ epithelia (EOE) tissues from an Apert patient carrying the S252W FGFR2 mutation. Apert primary pulp and EOE cells were es

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11

KUMABE, Shunji, Michiko NAKATSUKA, Gi-Seup KIM, et al. "Human Dental Pulp Cell Culture and Cell Transplantation with an Alginate Scaffold." Okajimas Folia Anatomica Japonica 82, no. 4 (2006): 147–56. http://dx.doi.org/10.2535/ofaj.82.147.

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12

FUJIWARA, Shiro, Shunji KUMABE, and Yasutomo IWAI. "Isolated Rat Dental Pulp Cell Culture and Transplantation with an Alginate Scaffold." Okajimas Folia Anatomica Japonica 83, no. 1 (2006): 15–24. http://dx.doi.org/10.2535/ofaj.83.15.

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13

Gupta, Ashu, Saroj Thakur, Vishal Sharma, Anshu Minocha, Bhanu Singh, and Rambhika Thakur. "Radix Entomolaris: An Endodontic Challenge." Dental Journal of Advance Studies 01, no. 01 (2013): 058–60. http://dx.doi.org/10.1055/s-0038-1670598.

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AbstractVariation of root canal anatomy is always a challenge for accurate diagnosis and successful endodontic therapy. A thorough knowledge of most common anatomic characteristics and their possible variations is essential for the clinician. The hard tissue repository of the human dental pulp takes on numerous configurations and shapes. These aberrations occur so often that they can be considered as normal anatomy. Radix Entomolaris (RE) is one such aberration where an extra root is present on the distolingual aspect of mandibular first molar (molar with 3 roots). This article presents two ca

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14

Liu, Guolin, Guoquan Xu, Zhenhua Gao, et al. "Demineralized Dentin Matrix Induces Odontoblastic Differentiation of Dental Pulp Stem Cells." Cells Tissues Organs 201, no. 1 (2015): 65–76. http://dx.doi.org/10.1159/000440952.

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The aim of this study was to investigate the effect of demineralized dentin matrix (DDM) on dental pulp stem cells (DPSCs) and the potential of complexes with DPSCs and DDM for mineralized tissue formation. Stem cells derived from the dental pulp of healthy pigs aged 18 months were isolated and cultured. DPSCs were incubated with alpha-minimum essential medium treated with DDM extract at 1 mg/ml (DDM1) or 10 mg/ml (DDM10). The concentrations of 3 growth factors in DDM extract was measured by enzyme-linked immunosorbent assay. Adhesion of DPSCs on DDM and hydroxyapatite-tricalcium phosphate (HA

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15

Suazo Galdames, Iván, Ignacio Roa Henríquez, and Mario Cantín L. "Sex Chromatin in Dental Pulp: Performance of Diagnosis Test and Gold Standard Generation." International Journal of Morphology 28, no. 4 (2010): 1093–96. http://dx.doi.org/10.4067/s0717-95022010000400017.

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16

Nicklisch, Nicole, Oliver Schierz, Frieder Enzmann, et al. "Dental pulp calcifications in prehistoric and historical skeletal remains." Annals of Anatomy - Anatomischer Anzeiger 235 (May 2021): 151675. http://dx.doi.org/10.1016/j.aanat.2021.151675.

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17

Kumar, Rahul, Nishant Gandhi, Roshan Shetty, and Anuradha Patil. "Radix Entomolaris." Journal of Contemporary Dentistry 2, no. 1 (2012): 33–37. http://dx.doi.org/10.5005/jcd-2-1-33.

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Abstract Variation of root canal anatomy is always a challenge for accurate diagnosis and successful endodontic therapy. A thorough knowledge of most common anatomic characteristics and their possible variations is essential for the clinician. The hard tissue repository of the human dental pulp takes on numerous confi gurations and shapes. These aberrations occur so often that they can be considered as normal anatomy. Radix entomolaris (RE) is one such aberration where an extra root is present on the distolingual aspect of mandibular first molar (molar with 3 roots). This article presents one

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18

Balic, Anamaria, Barbara Rodgers, and Mina Mina. "Mineralization and Expression of Col1a1-3.6GFP Transgene in Primary Dental Pulp Culture." Cells Tissues Organs 189, no. 1-4 (2008): 163–68. http://dx.doi.org/10.1159/000154813.

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19

Ghoddusi, Jamileh. "Ultrastructural changes in feline dental pulp with periodontal disease." Microscopy Research and Technique 61, no. 5 (2003): 423–27. http://dx.doi.org/10.1002/jemt.10307.

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20

Lombardi, T., J. Samson, J. Mühlhauser, G. Fiore-Donno, N. Maggiano, and M. Castellucci. "Expression of intermediate filaments and actins in human dental pulp and embryonic dental papilla." Anatomical Record 234, no. 4 (1992): 587–92. http://dx.doi.org/10.1002/ar.1092340414.

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21

Mina, Mina, and Alen Braut. "New Insight into Progenitor/Stem Cells in Dental Pulp Using Col1a1-GFP Transgenes." Cells Tissues Organs 176, no. 1-3 (2004): 120–33. http://dx.doi.org/10.1159/000075033.

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22

El-Kersh, Ahmed Othman Fathy Othman, Gehan El-Akabawy, and Rasha H. Al-Serwi. "Transplantation of human dental pulp stem cells in streptozotocin-induced diabetic rats." Anatomical Science International 95, no. 4 (2020): 523–39. http://dx.doi.org/10.1007/s12565-020-00550-2.

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23

Shah, Dishant, Tyler Lynd, Donald Ho, et al. "Pulp–Dentin Tissue Healing Response: A Discussion of Current Biomedical Approaches." Journal of Clinical Medicine 9, no. 2 (2020): 434. http://dx.doi.org/10.3390/jcm9020434.

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Dental pulp tissue exposed to mechanical trauma or cariogenic process results in root canal and/or periapical infections, and conventionally treated with root canal procedures. The more recent regenerative endodontic procedure intends to achieve effective root canal disinfection and adequate pulp–dentin tissue regeneration; however, numerous limitations are reported. Because tooth is composed of vital soft pulp enclosed by the mineralized hard tissue in a highly organized structure, complete pulp–dentin tissue regeneration has been challenging to achieve. In consideration of the limitations an

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24

Marchetti, C., P. Poggi, A. Calligaro, and A. Casasco. "Lymphatic vessels of the human dental pulp in different conditions." Anatomical Record 234, no. 1 (1992): 27–33. http://dx.doi.org/10.1002/ar.1092340104.

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25

Lombardi, T., and G. Fiore-Donno. "Distribution of Neural and Neural-Crest-Related Antigens in Human Dental Pulp by Immunohistochemistry." Cells Tissues Organs 147, no. 1 (1993): 35–39. http://dx.doi.org/10.1159/000147478.

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26

Levin, L. G., A. J. Banes, and G. Bergenholtz. "A method for isolation of viable cells from human dental pulp." Journal of Tissue Culture Methods 11, no. 1 (1988): 23–26. http://dx.doi.org/10.1007/bf01404410.

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27

Salazar-de-Santiago, Alfredo, Francisco J. Avelar-González, Juan Manuel Díaz, et al. "Expression of Enamel Proteins in Human Dental Pulp Stem Cells by the Effect of extracellular Matrix." International Journal of Morphology 38, no. 6 (2020): 1742–50. http://dx.doi.org/10.4067/s0717-95022020000601742.

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28

Honda, Masaki J., Yuka Shinmura, and Yoshinori Shinohara. "Enamel Tissue Engineering Using Subcultured Enamel Organ Epithelial Cells in Combination with Dental Pulp Cells." Cells Tissues Organs 189, no. 1-4 (2008): 261–67. http://dx.doi.org/10.1159/000151743.

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29

Hosoya, Akihiro, Akira Yukita, Kunihiko Yoshiba, Nagako Yoshiba, Masafumi Takahashi, and Hiroaki Nakamura. "Two Distinct Processes of Bone-like Tissue Formation by Dental Pulp Cells after Tooth Transplantation." Journal of Histochemistry & Cytochemistry 60, no. 11 (2012): 861–73. http://dx.doi.org/10.1369/0022155412459741.

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30

Fristad, I., K. J. Heyeraas, I. H. Kvinnsland, and R. Jonsson. "Recruitment of immunocompetent cells after dentinal injuries in innervated and denervated young rat molars: an immunohistochemical study." Journal of Histochemistry & Cytochemistry 43, no. 9 (1995): 871–79. http://dx.doi.org/10.1177/43.9.7543913.

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The dental pulp represents a peripheral end-organ deprived of a collateral nerve supply. After inferior alveolar nerve (IAN) axotomy, rat molar pulp is denervated over a period of at least 6 days. Therefore, rat molar pulp was used as an experimental model to study the effect of sensory nerve fibers on influx of immunocompetent cells after dentinal injury. In the present study we performed a quantitative analysis of CD43+, CD4+, CD11b+, and I-A antigen-expressing cells subjacent to dentinal cavities in denervated and innervated first mandibular molars. For visualization of nerve fibers, antibo

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31

Sawa, Yoshihiko, Shin-ichiro Kuroshima, Yuji Yamaoka, and Shigemitsu Yoshida. "Intracellular Distribution of Desmoplakin in Human Odontoblasts." Journal of Histochemistry & Cytochemistry 53, no. 9 (2005): 1099–108. http://dx.doi.org/10.1369/jhc.4a6525.2005.

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Coexpression of desmosomal proteins and vimentin has been reported in a specific mesenchymal phenotype. This study investigated the expression of vimentin-binding desmosomal proteins in human dental pulp fibroblasts (DPF) and odontoblasts. The dental pulp has no cells expressing desmocollin (DSC) 1–3, desmoglein (DSG) 1–3, junction plakoglobin (JUP), or desmoplakin (DPK) 1 and 2 except for odontoblasts expressing DPK. A confocal image by laser-scanning microscopy demonstrated the diffuse distribution of DPK in the cytoplasm throughout the odontoblast processes. In culture, the mRNA expression

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32

Duan, Wei, Yufei Chen, Qi Zhang, Xiang Lin, and Xiaoyu Yang. "Refined tooth and pulp segmentation using U-Net in CBCT image." Dentomaxillofacial Radiology 50, no. 6 (2021): 20200251. http://dx.doi.org/10.1259/dmfr.20200251.

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Objectives The aim of this study was extracting any single tooth from a CBCT scan and performing tooth and pulp cavity segmentation to visualize and to have knowledge of internal anatomy relationships before undertaking endodontic therapy. Methods: We propose a two-phase deep learning solution for accurate tooth and pulp cavity segmentation. First, the single tooth bounding box is extracted automatically for both single-rooted tooth (ST) and multirooted tooth (MT). It is achieved by using the Region Proposal Network (RPN) with Feature Pyramid Network (FPN) method from the perspective of panora

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33

Tung, P. S., C. Domenicucci, S. Wasi, and J. Sodek. "Specific immunohistochemical localization of osteonectin and collagen types I and III in fetal and adult porcine dental tissues." Journal of Histochemistry & Cytochemistry 33, no. 6 (1985): 531–40. http://dx.doi.org/10.1177/33.6.3889139.

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Affinity-purified antibodies have been used in combination with the peroxidase-antiperoxidase technique to study the distribution of osteonectin and collagen types I and III in porcine dental tissues. Tissue sections (2 mm thick), including unerupted (fetal) or erupted (adult) teeth, were fixed in periodate-lysine-paraformaldehyde, demineralized in 12% w/v ethylenediaminetetraacetic acid, and after embedding, 6 micron sections were prepared for immunolocalization. Strong staining for osteonectin was observed in dentine of unerupted teeth and in the associated alveolar bone. Light to moderate s

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34

Yi, Qiao, Ousheng Liu, Fei Yan, et al. "Analysis of Senescence-Related Differentiation Potentials and Gene Expression Profiles in Human Dental Pulp Stem Cells." Cells Tissues Organs 203, no. 1 (2016): 1–11. http://dx.doi.org/10.1159/000448026.

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Introduction: Dental pulp stem cell (DPSC)-mediated dental pulp regeneration is considered a promising method for the treatment of deep caries with pulpitis. However, mesenchymal stem cell (MSC) senescence is an adverse factor from the perspective of cell-based therapies. In this study, we investigated the characteristics and expression profiles of DPSCs from young and old donors. Methods: DPSCs from young and old donors were cultured in differentiation medium, and their differentiation potentials were assessed. Long noncoding RNA (LncRNA) microarray assays and a bioinformatic analysis were pe

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35

Karbanová, Jana, Tomáš Soukup, Jakub Suchánek, Robert Pytlík, Denis Corbeil, and Jaroslav Mokrý. "Characterization of Dental Pulp Stem Cells from Impacted Third Molars Cultured in Low Serum-Containing Medium." Cells Tissues Organs 193, no. 6 (2011): 344–65. http://dx.doi.org/10.1159/000321160.

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36

Kajol Relan, Manoj Chandak, Pooja Chandak, Madhulika Chandak, Chanchal Rathi, and Shruti Mishra. "Antibiotics: A changing scenario in Regenerative Endodontics." International Journal of Research in Pharmaceutical Sciences 11, SPL4 (2020): 1453–57. http://dx.doi.org/10.26452/ijrps.v11ispl4.4321.

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The main aim of Endodontics is to either prevent the endodontic disease or to treat it. This is achieved by maintaining the pulp health in cases of pulp inflammation. If there is pulp necrosis, pulp health can be maintained by regenerating the healthy pulp tissue. Hence various researches and the clinical studies tried to regenerate the healthy functioning pulp-dentin complex. Regenerative dentistry aims to biologically replace the dental tissues along with their supporting structures. Regenerative Endodontics can be defined as “ biologically based procedures designed to replace damaged struct

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37

Iijima, Tadahiko, and Jing-Qi Zhang. "Three-dimensional wall structure and the innervation of dental pulp blood vessels." Microscopy Research and Technique 56, no. 1 (2002): 32–41. http://dx.doi.org/10.1002/jemt.10007.

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38

Nishikawa, Sumio, and Fumie Sasaki. "Apoptosis of Dental Pulp Cells and Their Elimination by Macrophages and MHC Class II-expressing Dendritic Cells." Journal of Histochemistry & Cytochemistry 47, no. 3 (1999): 303–11. http://dx.doi.org/10.1177/002215549904700304.

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39

Struys, T., M. Moreels, W. Martens, R. Donders, E. Wolfs, and I. Lambrichts. "Ultrastructural and Immunocytochemical Analysis of Multilineage Differentiated Human Dental Pulp- and Umbilical Cord-Derived Mesenchymal Stem Cells." Cells Tissues Organs 193, no. 6 (2011): 366–78. http://dx.doi.org/10.1159/000321400.

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40

ROCHA NETO, Pedro Carlos da ROCHA, Lucileide de Castro OLIVEIRA, Marcilio Dias Chaves de OLIVEIRA, Leão Pereira PINTO, Bruno César de Vasconcelos GURGEL, and Hébel Cavalcanti GALVÃO. "Dens invaginatus: case report." RGO - Revista Gaúcha de Odontologia 63, no. 2 (2015): 219–26. http://dx.doi.org/10.1590/1981-863720150002000132564.

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Dens invaginatus is one of the most frequent malformations in dental elements. It can affect all teeth, even primary and supernumerary ones. It consists of an invagination of the crown surface, which happens during odontogenesis and penetrates the interior of the pulp chamber of the dental elements involved. In some cases, it can reach the apical tooth area. The maxillary lateral incisor is the most common site of occurrence. Due to its complex and variable anatomy, the tooth may present pulp necrosis and open apex, making it difficult to salvage. Oehlers classified them into types I, II, and

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41

Wadekar, Swati Ishwar, Dipali Yogesh Shah, Jimish Rajiv Shah, and Kinjal Mahesh Gathani. "Endodontic Management of a Three-rooted Mandibular First Premolar associated with Taurodontism." Journal of Operative Dentistry & Endodontics 1, no. 2 (2016): 90–92. http://dx.doi.org/10.5005/jp-journals-10047-0019.

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ABSTRACT Introduction Taurodontism is a morpho-anatomic variation in tooth anatomy that rarely affects mandibular premolars. Literature is replete with mandibular first premolars presenting atypical additional root canals, but concurrent presence of three roots and taurodontism is exceptional. Materials and methods This case report describes the successful endodontic diagnosis and management of a rare case of taurodontism in a mandibular first premolar with chronic apical periodontitis. Cone beam computed tomography (CBCT) facilitated the diagnosis of three roots and root canals associated wit

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42

Yoshida, Shigemitsu, and Hayato Ohshima. "Distribution and organization of peripheral capillaries in dental pulp and their relationship to odontoblasts." Anatomical Record 245, no. 2 (1996): 313–26. http://dx.doi.org/10.1002/(sici)1097-0185(199606)245:2<313::aid-ar14>3.0.co;2-s.

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43

Matsumoto, Yuushi, Bi Zhang, and Seiji Kato. "Lymphatic networks in the periodontal tissue and dental pulp as revealed by histochemical study." Microscopy Research and Technique 56, no. 1 (2002): 50–59. http://dx.doi.org/10.1002/jemt.10006.

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44

Martin, Anna, Hagen Gasse, and Carsten Staszyk. "Absence of lymphatic vessels in the dog dental pulp: an immunohistochemical study." Journal of Anatomy 217, no. 5 (2010): 609–15. http://dx.doi.org/10.1111/j.1469-7580.2010.01298.x.

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45

Datta, Piyali, Shabnam Zahir, Gautam Kumar Kundu, and Kaushik Dutta. "Different Methods of Studying Root Canal Morphology of Human Tooth: A Review." Bangladesh Journal of Dental Research & Education 5, no. 2 (2015): 59–63. http://dx.doi.org/10.3329/bjdre.v5i2.24718.

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Successful root canal therapy requires an in-depth knowledge of root canal morphology.False assumptions about the root canal anatomy of teeth may lead to misdiagnosis, missed canals, improper debridement and breakage of root canal instruments during root canal treatment. The objective of this paper was to review the various methods used to study and understand root canal systems. The complexity of root canal morphology presents a challenge to any clinician. Any attempt to perform root canal therapy must be preceded with a thorough understanding of the anatomy of both the pulp chamber and the r

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46

Honma, Shiho, Kunitaka Taki, Shi Lei, Hitoshi Niwa, and Satoshi Wakisaka. "Immunohistochemical Localization of SNARE Proteins in Dental Pulp and Periodontal Ligament of the Rat Incisor." Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology 293, no. 6 (2010): 1070–80. http://dx.doi.org/10.1002/ar.21106.

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47

Tritsaroli, Paraskevi. "A Case of Dental Fusion in Primary Dentition from Late Bronze Age Greece." Balkan Journal of Dental Medicine 22, no. 2 (2018): 102–5. http://dx.doi.org/10.2478/bjdm-2018-0018.

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SummaryBackground/Aim: Dental fusion is a developmental abnormality that can occur in primary and/or permanent dentition.Case report: A case of double primary teeth from a Late Bronze Age cemetery in Greece is presented. Age estimation of the skeleton was based on dental eruption and development as well as on fusion of primary ossification centres of the cranial and post-cranial skeleton. Analysis of double teeth used morphology, anatomy, location, tooth count and radiological examination. Results showed a 18 month infant. Primary lower right central and lateral incisors were joined by the den

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48

Galler, Kerstin M., Manuel Weber, Yüksel Korkmaz, Matthias Widbiller, and Markus Feuerer. "Inflammatory Response Mechanisms of the Dentine–Pulp Complex and the Periapical Tissues." International Journal of Molecular Sciences 22, no. 3 (2021): 1480. http://dx.doi.org/10.3390/ijms22031480.

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The macroscopic and microscopic anatomy of the oral cavity is complex and unique in the human body. Soft-tissue structures are in close interaction with mineralized bone, but also dentine, cementum and enamel of our teeth. These are exposed to intense mechanical and chemical stress as well as to dense microbiologic colonization. Teeth are susceptible to damage, most commonly to caries, where microorganisms from the oral cavity degrade the mineralized tissues of enamel and dentine and invade the soft connective tissue at the core, the dental pulp. However, the pulp is well-equipped to sense and

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49

Daud, Sulinda, Phrabhakaran Nambiar, Mohammad Zakir Hossain, et al. "Removal of the apical one-third of the root improves the fixation process of the dental pulp in teeth." Journal of Histotechnology 39, no. 3 (2016): 81–87. http://dx.doi.org/10.1080/01478885.2016.1164377.

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50

Zhang, Jing-Qi, Kengo Nagata, and Tadahiko Iijima. "Scanning electron microscopy and immunohistochemical observations of the vascular nerve plexuses in the dental pulp of rat incisor." Anatomical Record 251, no. 2 (1998): 214–20. http://dx.doi.org/10.1002/(sici)1097-0185(199806)251:2<214::aid-ar9>3.0.co;2-y.

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