Academic literature on the topic 'Dentin-pulp complex'

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Journal articles on the topic "Dentin-pulp complex"

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Simon, S. R. J., A. Berdal, P. R. Cooper, P. J. Lumley, P. L. Tomson, and A. J. Smith. "Dentin-Pulp Complex Regeneration." Advances in Dental Research 23, no. 3 (2011): 340–45. http://dx.doi.org/10.1177/0022034511405327.

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Dentistry is entering an exciting era in which many of the advances in biotechnology offer opportunities for exploitation in novel and more effective therapies. Pulp healing is complex and dependent on the extent of injury, among many other factors. Many of the molecular and cellular processes involved in these healing events recapitulate developmental processes. The regulation of odontoblast activity is clearly central to pulp healing, and an understanding of the mechanisms involved in these processes is necessary to enable laboratory studies to be translated to clinic application. Transcript
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Iliescu, Alexandru Andrei, Iulia Roxana Marinescu, Stelian Mihai Sever Petrescu, and Irina Maria Gheorghiu. "DENTIN-PULP COMPLEX IN DEEP CARIES." Romanian Journal for Dental Research 1, no. 3 (2024): 77–89. http://dx.doi.org/10.58179/rjdr1306.

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Deep caries progress highlights the gradual shift from reactionary to reparative tertiary dentine as main feature illustrated by transition between the secondary and tertiary dentin. Three sorts of odontoblasts are described to exhibit their dentinogenic potential in genesis of reparative dentine, the still active primary odontoblasts, the formerly quiescent odontoblasts recently reactivated by molecular signals sent from carious lesion, and the secondary odontoblasts resulting from pulp stem cells. This complex cellular secretor involvement in dentinogenesis presume a range of resulting matri
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Kitamura, Chiaki, Tatsuji Nishihara, Masamichi Terashita, Yasuhiko Tabata, and Ayako Washio. "Local Regeneration of Dentin-Pulp Complex Using Controlled Release of FGF-2 and Naturally Derived Sponge-Like Scaffolds." International Journal of Dentistry 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/190561.

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Restorative and endodontic procedures have been recently developed in an attempt to preserve the vitality of dental pulp after exposure to external stimuli, such as caries infection or traumatic injury. When damage to dental pulp is reversible, pulp wound healing can proceed, whereas irreversible damage induces pathological changes in dental pulp, eventually requiring its removal. Nonvital teeth lose their defensive abilities and become severely damaged, resulting in extraction. Development of regeneration therapy for the dentin-pulp complex is important to overcome limitations with presently
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Sandra, Ferry, Andri Sutanto, Widya Wulandari, et al. "Crucial Triad in Pulp-Dentin Complex Regeneration: Dental Stem Cells, Scaffolds, and Signaling Molecules." Indonesian Biomedical Journal 15, no. 1 (2023): 25–46. http://dx.doi.org/10.18585/inabj.v15i1.2265.

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BACKGROUND: Pulp damage can lead to dentinogenesis impairment, irreversible pulpitis, or pulp necrosis. Despite being the most used endodontic procedure to treat damaged pulp, root canal therapy only results in nonvital teeth which are prone to fractures and secondary infection. Pulp-dentin regeneration has a potential to regenerate structure similar to normal pulp-dentin complex, and can be achieved by combining dental stem cells, scaffold, and signaling molecules. This article reviews the role of various types of dental stem cells, scaffolds, signaling molecules, and their combinations in re
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Ali Hassan, Shaik, Sumit Bhateja, Geetika Arora, and Francis Prathyusha. "Biomarkers in dentin pulp complex." IP Journal of Paediatrics and Nursing Science 3, no. 2 (2020): 34–37. http://dx.doi.org/10.18231/j.ijpns.2020.008.

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Florimond, Marion, Sandra Minic, Paul Sharpe, Catherine Chaussain, Emmanuelle Renard, and Tchilalo Boukpessi. "Modulators of Wnt Signaling Pathway Implied in Dentin Pulp Complex Engineering: A Literature Review." International Journal of Molecular Sciences 23, no. 18 (2022): 10582. http://dx.doi.org/10.3390/ijms231810582.

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The main goal of vital pulp therapy (VPT) is to preserve the vitality of the pulp tissue, even when it is exposed due to bacterial invasion, iatrogenic mechanical preparation, or trauma. The type of new dentin formed as a result of VPT can differ in its cellular origin, its microstructure, and its barrier function. It is generally agreed that the new dentin produced by odontoblasts (reactionary dentin) has a tubular structure, while the dentin produced by pulp cells (reparative dentin) does not or has less. Thus, even VPT aims to maintain the vitality of the pulp. It does not regenerate the de
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Machla, Foteini, Ioannis Angelopoulos, Matthias Epple, Maria Chatzinikolaidou, and Athina Bakopoulou. "Biomolecule-Mediated Therapeutics of the Dentin–Pulp Complex: A Systematic Review." Biomolecules 12, no. 2 (2022): 285. http://dx.doi.org/10.3390/biom12020285.

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The aim of this systematic review was to evaluate the application of potential therapeutic signaling molecules on complete dentin-pulp complex and pulp tissue regeneration in orthotopic and ectopic animal studies. A search strategy was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement in the MEDLINE/PubMed database. Animal studies evaluating the application of signaling molecules to pulpectomized teeth for pulp tissue or dentin-pulp complex regeneration were included. From 2530 identified records, 18 fulfilled the eligibility crite
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Pashley, D. H. "Dynamics of the Pulpo-Dentin Complex." Critical Reviews in Oral Biology & Medicine 7, no. 2 (1996): 104–33. http://dx.doi.org/10.1177/10454411960070020101.

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Dentin has a relatively high water content due to its tubular structure. Once dentin is exposed, this intratubular water is free to move in response to thermal, osmotic, evaporative, or tactile stimuli. Fluid shifts across dentin are thought to cause sufficient shear forces on odontoblasts, nerve endings, nearby fibroblasts, and blood vessels to cause significant mechanical irritation, disruption, or damage, depending on the magnitude of the fluid shift. Even in the absence of fluid shifts, the water-filled tubules provide diffusion channels for noxious (i.e., bacterial products) substances wh
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Sequeira, Diana B., Patrícia Diogo, Brenda P. F. A. Gomes, João Peça, and João Miguel Marques Santos. "Scaffolds for Dentin–Pulp Complex Regeneration." Medicina 60, no. 1 (2023): 7. http://dx.doi.org/10.3390/medicina60010007.

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Background and Objectives: Regenerative dentistry aims to regenerate the pulp–dentin complex and restore those of its functions that have become compromised by pulp injury and/or inflammation. Scaffold-based techniques are a regeneration strategy that replicate a biological environment by utilizing a suitable scaffold, which is considered crucial for the successful regeneration of dental pulp. The aim of the present review is to address the main characteristics of the different scaffolds, as well as their application in dentin–pulp complex regeneration. Materials and Methods: A narrative revie
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Gomes-Silva, Wagner, Ana Carolina Prado-Ribeiro, Thaís Bianca Brandão, et al. "Postradiation Matrix Metalloproteinase-20 Expression and Its Impact on Dental Micromorphology and Radiation-Related Caries." Caries Research 51, no. 3 (2017): 216–24. http://dx.doi.org/10.1159/000457806.

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Recent evidence suggests that head-and-neck radiotherapy (HNRT) increases active forms of matrix metalloproteinase-20 (MMP-20) in human tooth crowns, degrading the dentin-enamel junction (DEJ) and leading to enamel delamination, which is a pivotal step in the formation of radiation-related caries (RRC). Additional participation of enzymatic degradation of organic matrix components in caries progression was attributed to MMP-20 in dentin. Therefore, the current study tested the hypothesis that MMP-20 is overexpressed in the DEJ, dentin-pulp complex components, and carious dentin of post-HNRT pa
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Dissertations / Theses on the topic "Dentin-pulp complex"

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Sulkala, M. (Merja). "Matrix metalloproteinases (MMPs) in the dentin-pulp complex of healthy and carious teeth." Doctoral thesis, University of Oulu, 2004. http://urn.fi/urn:isbn:9514274598.

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Abstract The dentin-pulp complex comprises mineralized dentin and the vital soft tissues encased inside dentin, i.e. odontoblasts and pulp tissue. During caries progression, the dentinal minerals are dissolved and eventually the collagenous organic matrix is degraded. However, the exact mechanisms and enzymes responsible for the organic matrix breakdown remain unknown. Matrix metalloproteinases (MMPs), a family of endopeptidases capable of degrading in concert virtually all extracellular matrix components, are expressed during normal dentin-pulp complex formation and maintenance. MMP activity
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Gangolli, Riddhi Ajit. "A Novel Biomimetic Scaffold for Guided Tissue Regeneration of the Pulp - Dentin Complex." Diss., Temple University Libraries, 2016. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/409954.

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Bioengineering<br>Ph.D.<br>60 % of school children have some form of untreated tooth decay or have suffered trauma to the front teeth which results in pulp damage. If left untreated, these teeth are susceptible to premature fracture/loss under daily stresses. In cases of adolescent tooth loss, teenagers cannot get dental implants until after the growth spurts; their only option is using removable dentures which lowers their quality of life. Conventional endodontic treatment (root canal treatment) is used in cases of pulp necrosis, but cannot be performed in immature permanent teeth due to majo
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Palosaari, H. (Heidi). "Matrix metalloproteinases (MMPs) and their specific tissue inhibitors (TIMPs) in mature human odontoblasts and pulp tissue:the regulation of expressions of fibrillar collagens, MMPs and TIMPs by growth factors, transforming growth factor-β1 (TGF-β1) and bone morphogenetic protein-2 (BMP-2)". Doctoral thesis, University of Oulu, 2003. http://urn.fi/urn:isbn:9514270789.

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Abstract Dentin formation in physiological and pathological conditions has been widely studied, but the events and regulation are still not completely understood. Odontoblasts, terminally differentiated post-mitotic cells located in a single cell layer around pulp tissue, synthesize and mineralize dentin organic matrix. Growth factors, such as TGF-β1 and BMP-2, have been implicated in the regulation of the responses of odontoblasts and pulp tissue to external irritation. Matrix metalloproteinases (MMPs), a family of 28 endopeptidases collectively capable of degrading virtually all extracellula
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Silva, Francine Lorencetti da. "Avaliação da expressão gênica de células da polpa dentária após estimulação com microesferas contendo mediadores lipídicos." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/58/58135/tde-14122015-085738/.

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Durante a resposta inflamatória alguns mediadores lipídicos, destacando-se o Leucotrieno B4 (LTB4) e a Prostaglandina E2 (PGE2), são liberados no meio e desencadeiam uma série de eventos moleculares e celulares. Não diferentemente do que ocorre em outros tecidos, eventos inflamatórios na polpa também geram a produção destes mediadores lipídicos. Na polpa, entretanto, há presença de células-tronco que persistiram e permanecem indiferenciadas, mas com potencial capacidade de diferenciação em células odontoblast-like. O objetivo do presente estudo foi avaliar a expressão de genes codificadores da
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Sakai, Vivien Thiemy. "Mecanismos envolvidos na diferenciação de células-tronco de dentes decíduos exfoliados humanos (SHED) em odontoblastos e células endoteliais." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/25/25133/tde-26052009-144852/.

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A engenharia de tecido pulpar tem como objetivo substituir a polpa dentária inflamada ou necrosada por um tecido saudável e funcional, capaz de formar nova dentina para reparar a estrutura dentária perdida. Assim, os objetivos deste trabalho foram: avaliar a habilidade de diferenciação de célulastronco de dentes decíduos exfoliados humanos (SHED) em odontoblastos funcionais, demonstrando a formação de tecido mineralizado in vivo; e estudar o efeito de VEGF em SHED com relação à estimulação de vias de sinalização celular (STAT3, AKT e ERK), proliferação, migração, formação de estruturas tubular
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Dalmolin, Ana Cláudia. "Avaliação histológica e imuno-histoquímica do complexo dentino-pulpar em modelo de recessão gengival com diferentes formulações de biovidros nanoparticulados para a obliteração de túbulos dentinários – estudo em ratos." Universidade Estadual de Ponta Grossa, 2018. http://tede2.uepg.br/jspui/handle/prefix/2581.

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Submitted by Angela Maria de Oliveira (amolivei@uepg.br) on 2018-07-31T12:54:31Z No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Ana Cláudia Dalmolin.pdf: 4507654 bytes, checksum: 94b0e5d7e5b5768e1913e17076d5138e (MD5)<br>Made available in DSpace on 2018-07-31T12:54:31Z (GMT). No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Ana Cláudia Dalmolin.pdf: 4507654 bytes, checksum: 94b0e5d7e5b5768e1913e17076d5138e (MD5) Previous issue date: 2018-02-22<br>Conselho Nacional de Desenvolvimento Científico e Tecno
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Ling, Patricia Lillian. "The effects of carbon-dioxide laser irradiation on the dentin-pulp complex of the rat incisor." 1995. http://catalog.hathitrust.org/api/volumes/oclc/46961482.html.

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Books on the topic "Dentin-pulp complex"

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International, Conference on Dentin/Pulp Complex (4th 2001 Kazusa Japan). Dentin/Pulp Complex: Proceedings of the International Conference on Dentin/Pulp Complex 2001. Quintessence Publishing, 2002.

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International, Conference on Dentin/Pulp Complex (1995 Chiba Japan). Dentin/pulp complex: Proceedings of the International Conference on Dentin/Pulp Complex 1995 and the International Meeting on Clinical Topics of Dentin/Pulp Complex. Quintessence Publishing Co., 1996.

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International Conference on Dentin/Pulp Complex (1995 Chiba, Japan). Dentin/pulp complex: Proceedings of the International Conference on Dentin/Pulp Complex 1995 and the International Meeting on Clinical Topics of Dentin/Pulp Complex. Edited by Shimono Masaki 1945-, Bergenholtz Gunnar, and International Meeting on Clinical Topics of Dentin/Pulp Complex (1995 : Chiba, Japan). Quintessence Publishing Co., 1996.

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Ishikawa, Tatsuya. Dentin/ Pulp Complex. Edited by Tatsuya Ishikawa. Quintessence Publishing Co., Inc., 2002.

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(Editor), Masaki Shimono, Hideaki Suda (Editor), and Takeyasu Maeda (Editor), eds. Dentin/Pulp Complex. Quintessence Publishing (Il), 1996.

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Book chapters on the topic "Dentin-pulp complex"

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Pozos-Guillén, Amaury, and Héctor Flores. "Dentin-Pulp Complex Regeneration." In Current Advances in Oral and Craniofacial Tissue Engineering. CRC Press, 2020. http://dx.doi.org/10.1201/9780429423055-11.

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de Mello Torres, Adriana Cristina, Ana Paula Martins Gomes, Claudio Hideki Kubo, and Carlos Rocha Gomes Torres. "Protection of the Dentin-Pulp Complex." In Modern Operative Dentistry. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-31772-0_9.

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Nakano, Yukiko, and Pamela Den Besten. "Fluoride Effects on the Dentin-Pulp Complex." In The Dental Pulp. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-55160-4_14.

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Burstyn-Cohen, Tal. "Cellular and Molecular Mechanisms Guiding the Development and Repair of the Dentin–Pulp Complex." In Contemporary Endodontics for Children and Adolescents. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-23980-9_2.

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Ahmed, Geraldine M., Eman A. Abouauf, Nermeen AbuBakr, Azza Ezz Elarab, and Karim Fawzy El-Sayed. "Stem Cell-Based Tissue Engineering for Functional Enamel and Dentin/Pulp Complex: A Potential Alternative to the Restorative Therapies." In Stem Cells. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-77052-5_10.

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"Dentin-Pulp Complex." In Ten Cate's Oral Histology. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-323-07846-7.00008-2.

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Mudumba, Divya. "Dentin–Pulp Interaction with Silver Diamine Fluoride." In Enamel and Dentin-Pulp Complex [Working Title]. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.114987.

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Silver diamine fluoride (SDF) is increasingly used as a non-invasive treatment modality for caries management, particularly in pediatric and geriatric populations. Understanding its impact on the dentin–pulp complex is crucial for assessing its efficacy and safety in preserving pulp health while arresting carious lesions. SDF application directly affects the dentin–pulp complex by interacting with dentin, potentially influencing pulp health and function. Exploring how SDF interacts with dentin and its effects on pulp tissue would provide valuable insights into the dentin–pulp complex. Also, de
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Alrafee, Shaimaa A. "Natural Vital Dental Pulp Therapy." In Natural Conservative Dentistry: An Alternative Approach to Solve Restorative Problems. BENTHAM SCIENCE PUBLISHERS, 2024. http://dx.doi.org/10.2174/9789815223194124010013.

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Curiosity in pharmaceutical greenery has blossomed due to the expanded productiveness of incoming herbal extract medicine and the rising concern in natural materials to avoid the undesirable effects of traditional drugs. This comes in the same line with the need to keep up pulp liveliness and function of the normal pulp tissue, which is essential for reparative dentin formation. In the previous decade, fully grown adult teeth with pulp exposure had fewer favorable results, and endodontic treatment choice has succeeded over other therapies. Now, eradicating microorganisms from dentin pulp compl
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Cosmina Ardelean, Lavinia, Codruta Victoria Tigmeanu, Alexandra Roi, and Laura-Cristina Rusu. "White Spot Lesions of Carious Etiology." In Enamel and Dentin-Pulp Complex. IntechOpen, 2024. http://dx.doi.org/10.5772/intechopen.115148.

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Demineralization-induced white spot lesions (WSL) are early non-cavitated carious lesions, representing the earliest stage of tooth decay, and appear as opaque, milky, porous areas, with a depth of only 40–130 μm. They are frequently found postfixed orthodontic treatment, because of the retentive nature of brackets and wires, and the inherent difficulties in maintaining proper oral hygiene, but can be found in non-orthodontic patients, as well. The main concern is of esthetic nature, but untreated WSL may evolve in dental caries, with important structural and functional consequences. The treat
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Sloan, Alastair J. "Biology of the Dentin-Pulp Complex." In Stem Cell Biology and Tissue Engineering in Dental Sciences. Elsevier, 2015. http://dx.doi.org/10.1016/b978-0-12-397157-9.00033-3.

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