Academic literature on the topic 'Denture Base Material'

Objectives. Polyamide-12 (PA) is a flexible material suited for denture bases and clasping. This study investigated its potential aging effects with a focus on surface roughness, color stability, and elasticity. Methods. PA specimens (Valplast) of 40 × 10 × 2mm and equally measuring PMMA specimens (Palapress) as control were fabricated. Color changes after storage in air, water, coffee, and red wine (n = 10) were measured using the CIE L*a*b color specification. Elasticity after thermocycling (1000, 3000, and 7000 cycles, n = 15) was measured by three-point bending testing. Mean surface roughness (Ra) was determined after storage in the liquids mentioned above and thermocycling (n = 10). Results. Tukey’s HSD test (P < 0.05) revealed statistically significant color changes of PA in red wine (ΔE = 4.27 after 12 days, EΔE = 6.90 after 12 days) and coffee (ΔE = 3.93 after 36 days) but no color changes in PMMA. Elastic modulus of PA was 845MPa and not affected by thermocycling (Tukey’s HSD test, P > 0.81). Dry specimens showed significantly decreased elasticity (P < 0.001). Mean surface roughness (PA 0.20 μm, PMMA 0.28 μm) did not change significantly after thermocycling or storage (Mann-Whitney U-test, 0.16 < P < 0.65). Significance. PA exhibited a higher susceptibility to discoloration than PMMA. Neither surface roughness nor elasticity of PA was altered by artificial aging.

Reembasadores resilientes temporários contendo fármacos antifúngicos foram sugeridos como um tratamento adjunto para estomatite protética. No entanto, antes de utilizar clinicamente estes reembasadores modificados em humanos, é importante avaliar a sua biocompatibilidade em modelos animais. Este estudo avaliou a biocompatibilidade in vivo de um reembasador resiliente temporário para base de prótese (Trusoft) modificado por agentes antimicrobianos em suas mínimas concentrações inibitórias (MCIs) para biofilme de Candida albicans. Dispositivos acrílicos intra-orais (DIOs) foram confeccionados individualmente para 60 ratos Wistar. Os ratos foram divididos em 6 grupos (n=5): 3 grupos controle (Negativo: sem DIO; Geral: DIO sem reembasamento; Positivo: DIO reembasado com Trusoft sem fármacos) e 3 grupos experimentais (DIOs reembasados com Trusoft modificados por fármacos em suas respectivas MCIs: 0,032 g de nistatina, 0,064 g de diacetato de clorexidina e 0,128 g de cetoconazol). Os ratos com ou sem os DIOs foram eutanasiados após 7 e 14 dias de avaliação. A análise histopatológica qualitativa foi realizada comparando-se fotomicrografias de secções histológicas, que foram obtidas utilizando um microscópio óptico que abrangeu transversalmente a região intermolares. As alterações morfológicas no epitélio e queratina foram analisadas quantitativamente através da realização de planimetria computadorizada. Os dados quantitativos foram analisados utilizando ANOVA 2-fatores e teste de Tukey (=0,05). A análise quantitativa mostrou que apenas o grupo com DIO contendo cetoconazol diminuiu significativamente a espessura e a área do estrato córneo em comparação com os outros grupos (p<0,05), que não apresentaram diferenças significativas entre si (p>0,05). Estes resultados estiveram de acordo com os obtidos para análise qualitativa. A incorporação de MCIs de nistatina e diacetato de clorexidina no Trusoft não induziram alterações histopatológicas na mucosa palatina de ratos, sugerindo a biocompatibilidade in vivo deste protocolo para o tratamento de estomatite protética.<br>Temporary resilient denture liners containing antifungal drugs have been suggested as an adjunct treatment for denture stomatitis. However, before clinically using these modified liners in humans, it is important to assess their biocompatibility in animal models. This study evaluated the in vivo biocompatibility of a temporary soft denture liner (Trusoft) modified by antimicrobial agents at their minimum inhibitory concentrations (MICs) for biofilm formation by Candida albicans. Methods: Acrylic intraoral devices (IODs) were individually made for 60 Wistar rats. The rats were divided into the following 6 groups (n=5): 3 control groups (Negative: without IOD; General: IOD without relining; Positive: IOD relined with Trusoft without drugs) and 3 experimental groups (IOD relined with Trusoft modified by drugs at MICs: 0.032 g for nystatin, 0.064 g for chlorhexidine diacetate, and 0.128 g for ketoconazole). The rats with or without the IODs were sacrificed after 7 or 14 days of evaluation. Histopathological qualitative analysis was performed by comparing photomicrographs of histological sections, which were obtained using an optical microscope that transversely covered the inter-molar region. Morphological changes in the epithelium and keratin were quantitatively analyzed by performing computerized planimetry. Quantitative data were analyzed using 2-way ANOVA and Tukey\'s test (=0.05). Quantitative analysis showed that only the group with IOD containing ketoconazole significantly decreased the thickness and area of the stratum corneum compared with the other groups (p<0.05), which showed no significant differences between each other (p>0.05). These results were in accordance with those obtained for qualitative analysis. Incorporation of MICs of nystatin and chlorhexidine diacetate in Trusoft did not induce histopathological changes in the palatal mucosa of rats, suggesting the in vivo biocompatibility of this protocol for treating denture stomatitis.

Thesis submitted in fulfilment of the requirements for the degree Master of Technology: Dental Technology in the Faculty of Health and Wellness Sciences at the Cape Peninsula University of Technology, 2012<br>Statement of problem It is well documented that water sorption and water solubility by auto-polymerizing resins have a negative impact on their physical properties and may lead to harmful tissue reactions. The presence of residual monomer is often identified as the main cause for adverse tissue reactions. To optimize the polymerization reaction, the use of the proper powder/liquid ratio is recommended in the fabrication of a dental appliance. It is also recommended that a dental appliance should be soaked in water for at least 24 hours before delivery to a patient, in order to reduce the possible adverse effect. For auto-polymerizing resins, associated with higher residual monomer levels than heat-cured resins, soaking the appliance at elevated temperatures (65ºC for 60 minutes), would reduce the residual monomer content more efficiently than at room temperature. This requires additional processing conditions from the technician or dentist. Changing the powder/liquid ratios, deliberately or not, may modify the residual monomer content of the final product. A relationship exists between the levels of residual monomer and water sorption. Also, residual monomer leaching into the oral fluids may lead to adverse effects such as, oral tissue irritation or a delayed hypersensitivity reaction. Aim of the study The aim of this study was to evaluate the effect of different powder/liquid ratios and different water temperatures on the levels of sorption and solubility of an auto-polymerizing resin material used for denture bases. The null-hypothesis tested was that there is no difference in sorption and solubility among groups of specimens made from an auto-polymerizing resin material soaked in water at different temperatures and/or fabricated with different powder/liquid ratios. Material and methods Specimens were made from cold-cure pour-type denture base resin (Type 2, Class 2) using different powder/liquid ratios and soaked at different soaking temperatures. One group of specimens fabricated with the manufacturer’s recommended powder/liquid ratio and soaked in water at 37ºC, served as the control group for both experiments. Custom-made stainless steel moulds were used to fabricate resin disks, with a diameter of 50mm and a thickness of 0.5mm. For the temperature-controlled experiment, identical specimens were prepared and stored in distilled water at 37ºC; 45ºC; 55ºC and 67ºC. For the ratio-controlled experiment, the ratios were increased incrementally for each group, starting with a 10% increase, followed by a 15%; 20% and 25% increase in monomer. Water sorption and solubility were tested in accordance with ISO Standard 1567 (1999). Specimens were weighed before and after water immersion, and desiccation. Water sorption and solubility were calculated using the difference in wet and dry mass and the volume of the specimens. The water sorption and solubility results were analyzed by means of analysis of variance. For multiple comparisons, Bonferroni simultaneous confidence intervals (α=0.05) were applied. Results For the ratio-controlled experiment, water sorption mean values varied from 24.148 μg/mm3 to 25.1333 μg/mm3. Statistically significant differences in mean values were found between the following groups: 0%-10%; 0%-15%; 0%-25%; 10%-20%; 15%-20% and 20%-25% ratio groups (P<.0001). Water solubility mean values varied from 0.616μg/mm3 to 0.932μg/mm3. Statistically significant differences in mean values were found between the following groups: 0%-15%; 0%-20%; 0%-25% and 10%-25% and 20%-25% ratio groups (P<.0001). For the temperature-controlled experiment, water sorption mean values varied from 24.185μg/mm3 to 26.434μg/mm3. Statistically significant differences in mean values were found between the following groups: 37ºC-45ºC; 37ºC-55ºC; 37ºC-67ºC; 45ºC-67ºC and 55ºC-67ºC temperature-controlled experiments (P<.0001). Water solubility mean values, for the same experimental groups, varied from 0.616μg/mm3 to 2.752μg/mm3. Statistically significant differences in mean values were found among all the 6 pairs of groups (P<.0001). Despite statistical differences, the water sorption and water solubility values of the tested resin for both experiments and all groups were within the ISO Standard 1567 (1999) specification limits. Conclusion For the ratio-controlled experiment, there was an inverse relationship between the mean sorption and solubility values with an increase in liquid in the mixture: low water sorption levels are associated with high solubility levels. The lower water sorption and higher solubility results for more fluid mixtures could be related to initial and residual high monomer content characteristic of auto-polymerizing materials. These higher levels of free monomer are consequently released upon immersion in water; hence the higher water solubility levels. For the temperature-controlled experiment, a higher soaking temperature resulted in an increase in water solubility levels. The higher solubility levels could be attributed to the higher soaking temperatures causing higher or faster monomer diffusion from the resin material. Except for the 67ºC group, sorption is also lower with higher temperatures. It may be assumed that an additional polymerization process takes place and a subsequent more inaccessible polymer matrix is produced. For the 67ºC group, thermal expansion may explain the higher sorption level. Clinical Implications In terms of the sorption and solubility results, this auto-polymerizing pour-type resin may be used as a denture base resin. Even though statistical differences were demonstrated, the material satisfies the ISO 1567 (1999) requirements not only for auto-polymerizing but also for heat-polymerizing resins. Therefore, within limits, the mixture may be prepared more fluidly in order to improve flow of the material, without negatively affecting its sorption and solubility properties. Because solubility is higher at higher soaking temperatures, this property can be used to minimize monomer content of the appliance. Therefore, it is recommended that the dental appliance be soaked in warm water, below 67ºC, prior to delivery to the patient.

Thesis submitted in fulfilment of the requirements for the degree Master of Technology: Dental Technology in the Faculty of Health and Wellness Sciences at the Cape Peninsula University of Technology 2014<br>A pure nylon denture base does not bond chemically to the acrylic teeth processed into the denture. A mechanical bond is created by boring retention holes (diatorics) into the tooth structure. Concerns are that this form of retention might be insufficient. The purpose of this study is, firstly, to compare the retention of acrylic denture teeth in pure nylon dentures with that of teeth in conventional acrylic denture bases (the acrylic test pieces serving as the control standard), and secondly, to explore whether the technique prescribed for creating diatorics in acrylic teeth for use with pure nylon denture bases potentially has a weakening effect on the acrylic tooth structure. Two sets of 26 identical anterior one-tooth test pieces were created. The first set, labelled N, comprises two different pure nylon denture base materials labelled N1 and N2 – all have diatorics in the acrylic teeth. The second set, labelled A, comprised the same acrylic denture base. The set labelled A1 is the control standard without diatorics in the acrylic teeth and the set labelled A2 has diatorics within the acrylic teeth. A compressive load was applied to these test pieces at an angle of 45 degrees on the palatal surface of the tooth until fracture occurred or maximum load was reached. Resulting data from the first part of the research was analysed by One-Way ANOVA analysis. Resulting data for the second part of the research was analysed via the Chi-square cross- tabulation method. The One-Way ANOVA test revealed that there is no statistical difference in the mean fracture or maximum load in Newton values between the two A (acrylic denture base) groups. There is also no statistical difference in the mean fracture or maximum load in Newton values between the two N (pure nylon denture base) groups. There is, however, a statistically significant difference in the mean fracture or maximum load in Newton values of Group A in comparison to Group N. The Chi-square cross-tabulation indicated that the A groups have very similar breakage patterns, and the N groups have similar breakage patterns respectively. It is concluded that the mechanical retention of acrylic denture teeth in pure nylon denture bases is weaker than the mechanical and chemical retention of acrylic denture teeth in acrylic denture bases. It is also concluded that when diatorics are created as prescribed within the tooth, these do not weaken the tooth structure.