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Journal articles on the topic 'Depersonalization disorder'

Author: Grafiati
Published: 4 June 2021
Last updated: 26 July 2025

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1

Simeon, Daphne, and Eric Hollander. "Depersonalization Disorder." Psychiatric Annals 23, no. 7 (1993): 382–88. http://dx.doi.org/10.3928/0048-5713-19930701-09.

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2

Reutens, Sharon, Olav Nielsen, and Perminder Sachdev. "Depersonalization disorder." Current Opinion in Psychiatry 23, no. 3 (2010): 278–83. http://dx.doi.org/10.1097/yco.0b013e3283387ab4.

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3

&NA;. "Depersonalization disorder." Current Opinion in Psychiatry 23, no. 5 (2010): 490. http://dx.doi.org/10.1097/yco.0b013e32833c6c9c.

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Mendes de Oliveira, João Ricardo, and Matheus Fernandes de Oliveira. "Depicting Depersonalization Disorder." American Journal of Psychiatry 170, no. 3 (2013): 263–64. http://dx.doi.org/10.1176/appi.ajp.2012.12111413.

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5

Noyes, Russell, Samuel Kuperman, and Stephen B. Olson. "Desipramine: A Possible Treatment for Depersonalization Disorder*." Canadian Journal of Psychiatry 32, no. 9 (1987): 782–84. http://dx.doi.org/10.1177/070674378703200911.

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Primary depersonalization disorder is believed to be resistant to treatment. However, we report the successful treatment of a case with desipramine and suggest that, because there is a link between depersonalization and anxiety disorders, tricyclic antidepressants may prove effective for depersonalization.
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6

Sierra, Mauricio. "Depersonalization disorder: pharmacological approaches." Expert Review of Neurotherapeutics 8, no. 1 (2008): 19–26. http://dx.doi.org/10.1586/14737175.8.1.19.

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7

Cahill, CM, and KC Murphy. "Migraine and Depersonalization Disorder." Cephalalgia 24, no. 8 (2004): 686–87. http://dx.doi.org/10.1111/j.1468-2982.2004.00737.x.

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8

Krylov, V. I., and D. J. Butylin. "Clinical and psychopathological features associated of obsessive and depersonalization disorders." V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY, no. 3 (October 6, 2019): 42–47. http://dx.doi.org/10.31363/2313-7053-2019-3-42-47.

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The results of the study showed the presence of definite syntropia between various clinical variants of obsessive and depersonalization disorders. Autopsychic depersonalization is most characteristic for contrast obsessions, whereas somatopsychic depersonalization is for re-control obsessions. Derealization or allopsychic depersonalization are more often observed in patients with obstructive extracorporeal threats. Depersonalization of change is equally characteristic for patients with schizotypal disorder and psychogenic personality development, whereas depersonalization of loss and splitting
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9

Kline, Jim. "Realizing Derealization." International Journal of Jungian Studies 11, no. 2 (2019): 93–113. http://dx.doi.org/10.1163/19409060-01101002.

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Abstract Derealization is a dissociative disorder with the primary symptom of experiencing one’s surroundings as unreal, as if one were living in an elaborate dream. The disorder is usually associated with depersonalization, although according to Philip M. Coons (1996), it should not be considered a subset of depersonalization. Little research has been conducted on derealization unaccompanied by depersonalization. The following highlights a personal case study in which the characteristics of derealization are presented in an attempt to distinguish it from depersonalization and other dissociati
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10

Kobzar, Oksana, and Galyna Pyliagina. "Depersonalization-derealization Disorder in Men." Health of Man, no. 4 (December 28, 2023): 5–10. http://dx.doi.org/10.30841/2786-7323.4.2023.298545.

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The objective: to analyze the features of the course of depersonalization-derealization disorder (DDD) in men on the example of a clinical case. Materials and methods. The pilot study included 51 individuals, namely: 8 (15.7%) men and 43 (84.3%) women, with average age 21 years (SD=3.66) and 23.86 years (SD=6.88), respectively. Study participants had criteria for DDD according to the International Classification of Diseases for Mortality and Morbidity Statistics 10th revision (ICD-10). The following tests were used in the research, such as the Hamilton Anxiety Rating Scale (HAM-A), the Beck Ho
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Kobzar, Oksana, and Galyna Pyliagina. "Depersonalization-derealization Disorder in Men." Health of Man, no. 4 (December 28, 2023): 5–10. https://doi.org/10.30841/2786-7323.4.2023.298545.

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<strong>The objective:</strong>&nbsp;to analyze the features of the course of depersonalization-derealization disorder (DDD) in men on the example of a clinical case. <strong>Materials and methods.</strong>&nbsp;The pilot study included 51 individuals, namely: 8 (15.7%) men and 43 (84.3%) women, with average age 21 years (SD=3.66) and 23.86 years (SD=6.88), respectively. Study participants had criteria for DDD according to the International Classification of Diseases for Mortality and Morbidity Statistics 10th revision (ICD-10). The following tests were used in the research, such as the Hamilt
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12

Simeon, Daphne, Anna Riggio-Rosen, Orna Guralnik, Margaret Knutelska, and Dorothy Nelson. "Depersonalization Disorder: Dissociation and Affect." Journal of Trauma & Dissociation 4, no. 4 (2003): 63–76. http://dx.doi.org/10.1300/j229v04n04_05.

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13

Simeon, Daphne, Ruth Hwu, and Margaret Knutelska. "Temporal Disintegration in Depersonalization Disorder." Journal of Trauma & Dissociation 8, no. 1 (2007): 11–24. http://dx.doi.org/10.1300/j229v08n01_02.

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14

Simeon, Daphne, Rebecca J. Smith, Margaret Knutelska, and Lisa M. Smith. "Somatoform Dissociation in Depersonalization Disorder." Journal of Trauma & Dissociation 9, no. 3 (2008): 335–48. http://dx.doi.org/10.1080/15299730802139170.

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15

Simeon, Daphne, Orna Guralnik, Margaret Knutelska, Rachel Yehuda, and James Schmeidler. "Basal norepinephrine in depersonalization disorder." Psychiatry Research 121, no. 1 (2003): 93–97. http://dx.doi.org/10.1016/s0165-1781(03)00205-1.

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16

Phillips, Mary L., Nicholas Medford, Carl Senior, et al. "Depersonalization disorder: thinking without feeling." Psychiatry Research: Neuroimaging 108, no. 3 (2001): 145–60. http://dx.doi.org/10.1016/s0925-4927(01)00119-6.

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17

Madden, Sean P., and Patrick M. Einhorn. "Cannabis-Induced Depersonalization-Derealization Disorder." American Journal of Psychiatry Residents' Journal 13, no. 2 (2018): 3–6. http://dx.doi.org/10.1176/appi.ajp-rj.2018.130202.

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18

Guralnik, Orna, Timo Giesbrecht, Margaret Knutelska, Beth Sirroff, and Daphne Simeon. "Cognitive Functioning in Depersonalization Disorder." Journal of Nervous and Mental Disease 195, no. 12 (2007): 983–88. http://dx.doi.org/10.1097/nmd.0b013e31815c19cd.

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19

Sierra, Mauricio, Carl Senior, Jeffrey Dalton, et al. "Autonomic Response in Depersonalization Disorder." Archives of General Psychiatry 59, no. 9 (2002): 833. http://dx.doi.org/10.1001/archpsyc.59.9.833.

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20

Shoeib, Ali Mahmud, and Ereny Samir Gobrial. "Effectiveness of a Constructive Model of Variables related to Depersonalization- Derealization Disorder of University Students." International Journal of research in Educational Sciences 4, no. 4 (2021): 55–98. http://dx.doi.org/10.29009/ijres.4.4.2.

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The aims of this study were to identify the correlation between Depersonalization - Derealization Disorder (DPDR), anxiety, depression, and obsessive-compulsive disorders and to propose a constructive model of anxiety, depression and obsessive- compulsive disorders related to Depersonalization Derealization Disorder of university students. The sample consisted of 344 students (325 female and 19 male), with a mean age of (24.4) years. The study applied the following scales: structured clinical interview for depersonalization-derealization spectrum, Cambridge Depersonalization Scale, Generalised
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21

Fernandes, C. Pedro, B. Jorge, and D. Freitas. "Depersonalization and a severe form of agoraphobia: A case report and review." European Psychiatry 64, S1 (2021): S187—S188. http://dx.doi.org/10.1192/j.eurpsy.2021.496.

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IntroductionDepersonalization during panic attacks may be a feature of a subgroup of Panic disorder. Several studies suggest that such subgroup corresponds to a more clinically severe form of Panic Disorder, with earlier onset and a higher rate of comorbidity with other psychiatric disorders, such as obsessive-compulsive disorder and generalized anxiety disorder. It is also hypothesized that depersonalization during panic attacks may lead Panic disorder to evolve into Agoraphobia.ObjectivesTo present the case report of a patient with severe Agoraphobia, whose only symptom of Panic disorder was
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22

Onochie, Emeka, and Joseph Verghese. "A Case of Depersonalization-Derealization Disorder." BJPsych Open 11, S1 (2025): S313. https://doi.org/10.1192/bjo.2025.10752.

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Aims: Background: Depersonalization-derealization disorder (DPDR), classified under ICD–11 code 6B66, involves persistent or recurrent experiences of depersonalization, derealization, or both. Depersonalization refers to a sense of detachment from one’s thoughts, emotions, or body, whereas derealization involves perceiving the external world as unreal or distorted. These symptoms cause significant distress or impairment, are not attributable to other mental disorders, substance use, or medical conditions, and occur while reality testing remains intact.Methods: Case Report.An 18-year-old female
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23

Jones, Jennifer L., and Samuel P. Abraham. "DEPERSONALIZATION/DEREALIZATION DISORDER: JENNIFER’S RECOVERY STORY." International Journal of Research -GRANTHAALAYAH 7, no. 5 (2019): 66–70. http://dx.doi.org/10.29121/granthaalayah.v7.i5.2019.825.

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Depersonalization/derealization disorder is not commonly known. A nursing student experienced depersonalization/derealization attack just as she was taking her pharmacology examination at the end of the first year of nursing school. She was brought up in a supportive family. She reports no history of abuse or substance use. She succeeded well in high school and have had no serious panic episodes throughout her childhood and teen years. Jennifer tells the story of how on April 24th, 2017 her life changed.
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24

Phillips, Mary L., and Mauricio Sierra. "Depersonalization Disorder: A Functional Neuroanatomical Perspective." Stress 6, no. 3 (2003): 157–65. http://dx.doi.org/10.1080/1025389031000138538.

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25

Alphy, K. H. Aboobacker, Neeraj Zambare, Anuraag Aedma, and Pookala S. Bhat. "Depersonalization–derealization disorder: Letter to editor." Industrial Psychiatry Journal 33, no. 2 (2024): 429–30. https://doi.org/10.4103/ipj.ipj_266_24.

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26

Simeon, Daphne, Dan J. Stein, and Eric Hollander. "Treatment of depersonalization disorder with clomipramine." Biological Psychiatry 44, no. 4 (1998): 302–3. http://dx.doi.org/10.1016/s0006-3223(98)00023-7.

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27

Mendoza, Lilian, Ricard Navinés, José A. Crippa, et al. "Depersonalization and personality in panic disorder." Comprehensive Psychiatry 52, no. 4 (2011): 413–19. http://dx.doi.org/10.1016/j.comppsych.2010.09.002.

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28

Hürlimann, Franziska, Stephan Kupferschmid, and Andor E. Simon. "Cannabis-Induced Depersonalization Disorder in Adolescence." Neuropsychobiology 65, no. 3 (2012): 141–46. http://dx.doi.org/10.1159/000334605.

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29

Jennifer, L. Jones, and P. Abraham Samuel. "DEPERSONALIZATION/DEREALIZATION DISORDER: JENNIFER'S RECOVERY STORY." International Journal of Research - Granthaalayah 7, no. 5 (2019): 66–70. https://doi.org/10.5281/zenodo.3234685.

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Depersonalization/derealization disorder is not commonly known. A nursing student experienced depersonalization/derealization attack just as she was taking her pharmacology examination at the end of the first year of nursing school. She was brought up in a supportive family. She reports no history of abuse or substance use. She succeeded well in high school and have had no serious panic episodes throughout her childhood and teen years. Jennifer tells the story of how on April 24th, 2017 her life changed.
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30

Halder, Arghya, Partha Sarathi Kundu, and Sagarika Ray. "Are antidepressants effective in treating depersonalization derealization disorder: Inference from a case series." Telangana Journal of Psychiatry 9, no. 2 (2023): 162–66. http://dx.doi.org/10.4103/tjp.tjp_57_23.

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ABSTRACT Depersonalization derealization disorder is a clinical entity where the individual experiences a sense of being detached from his or her own body, feelings, sensations or actions, and the surroundings appear to be unreal, as if occurring in a dream. However, reality testing remains intact. Primary depersonalization derealization disorder is rare, while such experiences occur more commonly in association with anxiety disorders, depressive disorders, psychosis and substance use, and also in organic brain disorders like seizure disorder or head trauma. Such disorders lie somewhere in bet
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31

Ehrenreich, Yossi. "Chasing Bodily-Self Ghost: Interoception-Aided Hypnosis in the Treatment for Depersonalization-A Case Study." OBM Integrative and Complementary Medicine 08, no. 01 (2023): 1–14. http://dx.doi.org/10.21926/obm.icm.2301012.

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This paper aims to introduce a relatively novel approach for Hypnosis to treat Depersonalization-derealization Disorder (DPRD). Depersonalization is conceptualized as a disrupted interoceptive process disorder. Based on this conceptualization, Hypnotic intervention is tailored to counter the flawed process. It is exemplified by a case of a young man suffering from depersonalization disorder who couldn't bear looking at himself in the mirror. The hypnotic intervention used in this case is then explained by predictive coding theory.
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32

Ruzhenkova, V. V., V. A. Ruzhenkov, A. A. Bykova, and M. A. Kolosova. "Depersonalization and psychosensory disorders amongst young people who do not seek psychiatric help appeal for psychiatrysts (prevalence, clinical features and classification)." I.P. Pavlov Russian Medical Biological Herald 26, no. 1 (2018): 70–85. http://dx.doi.org/10.23888/pavlovj2018170-85.

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The importance of this study is justified by the high occurance frequency of this phenomenon amongst young people in the clinical structure of mental disorders and as well as in the framework of psychological defense mechanisms in psychiatrically healthy population. The question of the limits of depersonalization remains unresolved, as there is no single point of view regarding the syndromological affiliation, rendering it ambiguous to evaluate it as a productive or negative disorder.&#x0D; Aim. This study was aimed at verifying the prevalence and clinical structure of depersonalization sympto
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Ruzhenkova, V. V., V. A. Ruzhenkov, A. A. Bykova, and M. A. Kolosova. "Depersonalization and psychosensory disorders amongst young people who do not seek psychiatric help appeal for psychiatrysts (prevalence, clinical features and classification)." I.P. Pavlov Russian Medical Biological Herald 26, no. 1 (2018): 70–85. http://dx.doi.org/10.23888/pavlovj201826170-85.

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The importance of this study is justified by the high occurance frequency of this phenomenon amongst young people in the clinical structure of mental disorders and as well as in the framework of psychological defense mechanisms in psychiatrically healthy population. The question of the limits of depersonalization remains unresolved, as there is no single point of view regarding the syndromological affiliation, rendering it ambiguous to evaluate it as a productive or negative disorder.&#x0D; Aim. This study was aimed at verifying the prevalence and clinical structure of depersonalization sympto
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34

Jiménez-Genchi, Alejandro M. "Repetitive Transcranial Magnetic Stimulation Improves Depersonalization: A Case Report." CNS Spectrums 9, no. 5 (2004): 375–76. http://dx.doi.org/10.1017/s1092852900009366.

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AbstractDepersonalization disorder is a poorly understood and treatment-resistant condition. This report describes a patient with depersonalization disorder who underwent six sessions of repetitive transcranial magnetic stimulation on the left dorsolateral prefrontal cortex. Repetitive transcranial magnetic stimulation produced a 28% reduction on depersonalization scores.
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35

Saleem, Saad, Taqdees Khaliq, Mohammad Hammas Adil, and Fasih Hashmi. "Assessment of Physician Burnout and its Association with Musculoskeletal Disorder." Pakistan Armed Forces Medical Journal 72, no. 4 (2022): 1291–97. http://dx.doi.org/10.51253/pafmj.v72i4.5856.

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Objective: To assess burnout among doctors and to determine its association with a musculoskeletal disorder.&#x0D; Study Design: Cross sectional study.&#x0D; Place and Duration of Study: Government and Private Hospitals of Islamabad and Rawalpindi Pakistan, from Jun to Aug 2020.&#x0D; Methodology: Two hundred and forty doctors were included through two-stage cluster sampling from different departments of the selected hospitals. Maslach Burnout Inventory (MBI) was used to assess burnout. Second, Nordic Musculoskeletal Questionnaire (NMQ) was used to assess the musculoskeletal disorder.&#x0D; Re
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36

Sierra, Mauricio, Mary L. Phillips, Michelle V. Lambert, Carl Senior, Antony S. David, and John H. Krystal. "Lamotrigine in the Treatment of Depersonalization Disorder." Journal of Clinical Psychiatry 62, no. 10 (2001): 826–27. http://dx.doi.org/10.4088/jcp.v62n1012b.

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37

McEvoy, Katherine, Blair Anton, and Margaret S. Chisolm. "Depersonalization/Derealization Disorder After Exposure to Mefloquine." Psychosomatics 56, no. 1 (2015): 98–102. http://dx.doi.org/10.1016/j.psym.2014.08.001.

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38

SIMEON, DAPHNE, ORNA GURALNIK, SHIRA GROSS, DAN J. STEIN, JAMES SCHMEIDLER, and ERIC HOLLANDER. "The Detection and Measurement of Depersonalization Disorder." Journal of Nervous & Mental Disease 186, no. 9 (1998): 536–42. http://dx.doi.org/10.1097/00005053-199809000-00004.

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39

Segui, J., M. Ma´rquez, L. Garcia, J. Canet, L. Salvador-Carulla, and M. Ortiz. "Depersonalization in panic disorder: A clinical study." Comprehensive Psychiatry 41, no. 3 (2000): 172–78. http://dx.doi.org/10.1016/s0010-440x(00)90044-0.

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40

Sierra, Mauricio, Nick Medford, Geddes Wyatt, and Anthony S. David. "Depersonalization disorder and anxiety: A special relationship?" Psychiatry Research 197, no. 1-2 (2012): 123–27. http://dx.doi.org/10.1016/j.psychres.2011.12.017.

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41

Gerrans, Philip. "Depersonalization Disorder, Affective Processing and Predictive Coding." Review of Philosophy and Psychology 10, no. 2 (2018): 401–18. http://dx.doi.org/10.1007/s13164-018-0415-2.

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42

Nestler, Steffen, Mauricio Sierra, Emma-Louise Jay, and Anthony S. David. "Mindfulness and Body Awareness in Depersonalization Disorder." Mindfulness 6, no. 6 (2015): 1282–85. http://dx.doi.org/10.1007/s12671-015-0392-9.

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43

Wearne, Deborah, Guy J. Curtis, Amanda Genetti, Mathew Samuel, and Justin Sebastian. "Where pseudo-hallucinations meet dissociation: a cluster analysis." Australasian Psychiatry 25, no. 4 (2017): 364–68. http://dx.doi.org/10.1177/1039856217695706.

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Objectives: The possible link between cognitive areas of perception and integration of consciousness was examined using assessments of hallucinations and derealisation/depersonalization. Methods: Sixty-five subjects in three main diagnostic groups – posttraumatic stress disorder (PTSD), borderline personality disorder (BPD) and schizophrenia – identified by their treating psychiatrist as hearing voices were surveyed regarding characteristics of hallucinations, derealisation/depersonalization, delusions and childhood/adult trauma. Results: A cluster analysis produced two clusters predominantly
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44

Lobkov, S. A. "Depersonalization-derealization symptom complex in the clinic of manifest forms of schizophrenia." Acta Biomedica Scientifica 9, no. 4 (2024): 146–52. http://dx.doi.org/10.29413/abs.2024-9.4.16.

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Background. The issues of early diagnostics and prevention of schizophrenia, despite more than a century of their study, remain relevant. In recent decades, there has been an increase in interest in the study of depersonalization-derealization symptom complex in the context of verification of the initial manifestations of the disease. Meanwhile, ICD-10 does not include symptoms of depersonalization and derealization in the rank of diagnostically important symptoms for this pathology, and they are traditionally considered as manifestations of schizotypal disorders. The existing contradictions s
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45

Pienkos, Elizabeth, and Louis Sass. "“Robbed of my life”: The Felt Loss of Familiar and Engaged Presence in Depersonalization/Derealization Disorder." Journal of Phenomenological Psychology 53, no. 1 (2022): 51–81. http://dx.doi.org/10.1163/15691624-20221398.

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Abstract Depersonalization/derealization disorder (DPDR) is classified as a dissociative disorder in the DSM5. It is noteworthy that the symptoms of depersonalization and derealization are commonly found in many other psychological disorders, including schizophrenia spectrum disorders, while phenomenological features of schizophrenia are commonly found in DPDR. The current study attempts to clarify these apparent similarities via highly detailed phenomenological interviews with four persons diagnosed with DPDR. The data revealed four interrelated facets: 1, Loss of resonance, 2, Detachment fro
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46

Sharpe, Louise, Nicholas Tarrier, and Nicolina Rotundo. "Treatment of Delayed Post-Traumatic Stress Disorder Following Sexual Abuse: A Case Example." Behavioural and Cognitive Psychotherapy 22, no. 3 (1994): 233–42. http://dx.doi.org/10.1017/s1352465800013096.

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Recent advances have been made in the treatment of post-traumatic stress disorder (PTSD). Cognitive behavioural techniques have been reported in controlled trials to be very effective in reducing arousal symptoms associated with post-traumatic stress disorder, such as sleep disturbance, hypervigilance, intrusive thoughts and flashbacks. It remains unclear from the literature, however, how well these treatment modalities can alleviate post-traumatic stress disorder where the predominant clinical features are associated with depersonalization and dissociative states. Depersonalization is evident
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47

Kirberg, Manuela, and Monima Chadha. "Depersonalization, Meditation, and the Experience of (No-)Self." Journal of Consciousness Studies 31, no. 5 (2024): 151–77. http://dx.doi.org/10.53765/20512201.31.5.151.

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This paper aims to contribute to an integrated understanding of what goes missing in adverse meditation experiences and in cases of depersonalization disorder. Depersonalization disorder is characterized by distressing alterations in, and sometimes the complete disappearance of, the 'I'-sense. This paper examines the nature of the 'I'-sense and what it means to lose it from a Buddhist perspective. We argue for a nihilist position that the loss of the sense of self arises from misidentifications of the psychophysical complex with non-self elements, such as memories, thoughts, or body movements.
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48

Grigorieva, E. A., and A. L. Dyakonov. "Effect of Harmonic Sounds on a Depressive Episode with Depersonalization in Recurrent Depressive Disorder." Doctor.Ru 20, no. 5 (2021): 49–54. http://dx.doi.org/10.31550/1727-2378-2021-20-5-49-54.

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Study Objective: To attempt to impair steady pathological condition (depression with depersonalization) with harmonic sounds in order to potentially reduce or eliminate both depression and depersonalization. Study Design: descriptive study, clinical and physiological study. Materials and Methods. We examined 31 patients aged 18 to 40 years (mean age: 29.3 ± 1.2 years) with a depressive episode in recurrent depressive disorder. All patients had background electroencephalogram (EEG) (16 channels) recorded. Then, EEGs were subjected to spectral analysis using Brainlog, which identified maximum ex
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49

Harnic, D., A. Cardella, M. Mazza, et al. "Burn-out indexes in mental health services employees and satisfaction in patients with a diagnosis of bipolar disorder." European Psychiatry 26, S2 (2011): 214. http://dx.doi.org/10.1016/s0924-9338(11)71924-1.

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ObjectivesThe aim of our study is the investigation of burn-out indexes in public mental health services employees (psychiatrists, psychologists, nursing staff, care providers) working with patients affected by Bipolar Disorder in order to correlate them with patients’ indexes of satisfaction about received treatment and care.MethodsA sample of 20 employees of mental health services (psychiatrists, psychologists, nurses) and one consisting of 22 patients with a diagnosis of Bipolar Disorder have been recruited at the Bipolar Disorders Unit of the Day Hospital of Psychiatry of the A. Gemelli Ho
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Bykova, Anastasia Yu, Roman A. Bekker, and Yuriy V. Bykov. "ON THE DIFFICULTIES IN THE DIFFERENTIAL DIAGNOSIS BETWEEN PRIMARY DEPERSONALIZATION-DEREALIZATION DISORDER AND SCHIZOTYPAL DISORDER." Siberian Journal of Life Sciences and Agriculture 14, no. 1 (2022): 11–82. http://dx.doi.org/10.12731/2658-6649-2022-14-1-11-82.

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Abstract:
Purpose. In this article, we want to show to the reader (both with the thorough literature review, and with presentation of two clinical cases from our own practice), what might be the objective difficulties in differential diagnosis between primary depersonalization-derealization disorder (DPD, code 6B66 according to ICD-11, F48.1 according to ICD-10) and schizotypal disorder (STD, code 6A22 according to ICD-11, F21 according to ICD-10), what may be the cause of these difficulties, and how can a psychiatrist still distinguish between these disorders in his everyday clinical practice.&#x0D; Me
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