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1

Hill, Mary Kathleen Clark Russell Dunn. "Individual attachment styles and the correspondence/compensation hypotheses in relation to depression and depressive experiences." [Denton, Tex.] : University of North Texas, 2008. http://digital.library.unt.edu/permalink/meta-dc-9092.

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2

Ovuga, Emilio. "Depression and suicidal behavior in Uganda : validation the response inventory for stressful life events (RISLE) /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-350-7/.

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3

Kardegar, Nadia. "Electrical Brain Stimulation and Depressive-like Behavior in Guinea Pigs." Wright State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=wright1342408797.

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4

Lakey, Chad E., Jameson K. Hirsch, Lyndsay A. Nelson, and Sheri A. Nsamenang. "Effects of Contingent Self-Esteem on Depressive Symptoms and Suicidal Behavior." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/658.

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Contingent self-esteem, or self-worth hinged upon successfully meeting standards or attaining goals, requires continual maintenance and validation. Despite the inherent instability that accompanies contingent self-esteem, relatively little is known about how it relates to markers of mental health. A sample of 371 college students completed measures of self-esteem, contingent self-esteem, suicidal behaviors, and depression. Individuals with fragile low self-esteem, described as highly contingent, reported greater depressive symptoms and suicidal behavior. Among those with secure high self-esteem, or high yet noncontingent, depression and suicide risk were markedly lower. Therapeutically promoting positive but noncontingent self-worth may reduce poor mental health outcomes.
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5

Hill, Mary Kathleen. "Individual attachment styles and the correspondence/compensation hypotheses in relation to depression and depressive experiences." Thesis, University of North Texas, 2008. https://digital.library.unt.edu/ark:/67531/metadc9092/.

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Two hundred twenty individuals participated in the present study from a university population. The study examined the relationship among attachment styles to caregivers, relationship with God, depressive symptomology, and depressive experiences. Attachment theorists have suggested a connection between childhood attachment to caregivers and current attachment to God through the idea that individuals have "working models" that form how they interpret present relationships. For the most part, the results of the current study supported the idea of correspondence between attachment to caregiver and attachment to God. Individual attachment styles to caregivers matched their attachment style to God. However, when caregiver religiousness was included as a moderating variable, results supported the theory of combined compensation-correspondence for those with insecure attachments to caregivers. Individuals with insecure attachment to caregivers were more likely to compensate for their insecure attachment bonds through participation in religious activity, whereas their internal, private relationship with God corresponded with their previous insecure attachment bonds. Individuals with insecure attachment to caregivers were more likely to endorse symptoms of depression and report introjective, but not anaclitic, depressive experiences. With respect to attachment to God, introjective depressive experiences were positively related to both anxious and avoidant attachments, whereas, anaclitic depressive experiences were positively related only to anxious attachment to God. Anxious attachment to God was found to partially mediate the relationship between insecure attachment to caregivers and depression symptoms. Finally, attachment effects were similar across gender, ethnicity, and age, with some notable exceptions.
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6

McKinney, Jessica, Lauren Beuttel, Peter C. Britton, and Jameson K. Hirsch. "Posttraumatic Growth and Suicidal Behavior: Serial Effects via Time Perspective and Depressive Symptoms." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/613.

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7

Brioschi, Simone [Verfasser], and Dierk Frithjof [Akademischer Betreuer] Reiff. "Microglia promote synaptic loss and depressive-like behavior under chronic-stress exposure." Freiburg : Universität, 2019. http://d-nb.info/118819593X/34.

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8

Hirsch, Jameson Kenneth, Jessica Kelliher Rabon, Esther E. Reynolds, Alison L. Barton, and Edward C. Chang. "Perceived Stress and Suicidal Behaviors in College Students: Conditional Indirect Effects of Depressive Symptoms and Mental Health Stigma." Digital Commons @ East Tennessee State University, 2017. https://doi.org/10.1037/sah0000125.

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Suicide is a significant public health concern and the second leading cause of death for college students. Perceived stress, depression, and mental health stigma are established risk factors for suicidal behavior; however, their interrelationships are unknown. Data were collected from 913 collegiate housing residents (70.8% female; N = 646). Using data from self-report measures, depressive symptoms were examined as a mediator of the relation between stress and suicidal behavior, along with the moderating effect of mental health stigma. Depressive symptoms partially mediated the stress–suicide linkage, and mental health stigma was a significant moderator of the associations between stress and depression, depression and suicidal behavior, and stress and suicidal behavior. Stigmatized attitudes toward mental health treatment, including fear of social repercussion, may exacerbate the deleterious impact of stress on psychopathology and suicide risk. Individual-level therapeutic strategies targeting stress and psychopathology, as well as public health approaches that directly address and attempt to reduce mental health stigma, may reduce suicide risk in college students.
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9

Hirsch, Jameson K., Jessica Kelliher Rabon, Esther E. Reynolds, Alison L. Barton, and Edward C. Chang. "Perceived Stress and Suicidal Behaviors in College Students: Conditional Indirect Effects of Depressive Symptoms and Mental Health Stigma." Digital Commons @ East Tennessee State University, 2019. http://doi.org/10.1037/sah0000125.

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Suicide is a significant public health concern and the second leading cause of death for college students. Perceived stress, depression, and mental health stigma are established risk factors for suicidal behavior; however, their interrelationships are unknown. Data were collected from 913 collegiate housing residents (70.8% female; N = 646). Using data from self-report measures, depressive symptoms were examined as a mediator of the relation between stress and suicidal behavior, along with the moderating effect of mental health stigma. Depressive symptoms partially mediated the stress–suicide linkage, and mental health stigma was a significant moderator of the associations between stress and depression, depression and suicidal behavior, and stress and suicidal behavior. Stigmatized attitudes toward mental health treatment, including fear of social repercussion, may exacerbate the deleterious impact of stress on psychopathology and suicide risk. Individual-level therapeutic strategies targeting stress and psychopathology, as well as public health approaches that directly address and attempt to reduce mental health stigma, may reduce suicide risk in college students.
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10

Sudol, Kristine Yvonne. "The relationship of attachment style, sex-role, and depressive symptomatology." View full text, 2005.

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11

Montgomery, M., Byron D. Brooks, Fuschia M. Sirois, and Jameson Hirsch. "Social Support and Treatment Adherence in Fibromyalgia: Indirect effects of Depressive Symptoms." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/625.

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12

Lamkin, Donald Michael. "Inflammatory processes and depressive-like behavior in a syngeneic model of ovarian cancer." Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/693.

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Considerable data demonstrate a high prevalence of depression symptoms in patients with cancer, with some studies showing the prevalence for major depressive disorder (MDD) to be as high as 50%. Because depression researchers have found that a significant relationship exists between depression symptoms and indices of systemic inflammation and because several cancer types exploit the mechanisms of the body's inflammatory response to aid in their own progression, it was hypothesized that tumor in the body could be a cause of depression symptoms in cancer patients. Examination of this question was conducted using an immunocompetent mouse model of ovarian cancer and several measures of depressive-like and sickness behavior. Initial investigation of the model (Chapter 2) involved a series of pilot experiments that addressed methodology and demonstrated that ID8 murine ovarian carcinoma was capable of inducing elevated levels of systemic IL-6 and depressive-like behavior, specifically anhedonia as measured by a decrease in sucrose solution. In Chapter 3, a larger experiment (Experiment 1) was conducted that examined the effect of ovarian tumor on sucrose intake, food intake, body weight, locomotion, and rotarod performance. Results in the study indicated that sucrose-measured anhedonia in the model was not confounded by anorexia because tumor-bearing mice and control mice exhibited no significant difference in appetite. In Chapter 4, a second experimental factor, social housing, was added alongside tumor condition, and a second measure of depressive-like behavior, tail suspension test (TST) immobility, was added to measures from the previous experiment. The results of this second large experiment (Experiment 2) demonstrated that ovarian tumor had no significant effect on TST immobility, even though it did cause mice to exhibit less motor activity in the home cage. Housing condition did affect TST immobility. Mice that were individually-housed exhibited significantly more TST immobility than group-housed mice. Also, individually-housed mice exhibited less sucrose intake than group-housed mice. This gave rise to a significant interaction in sucrose preference among the four experimental groups where individually-housed tumor-bearing mice showed less sucrose preference than the other groups. In Chapter 5, systemic proinflammatory and antiinflammatory cytokines from both Experiment 1 and Experiment 2 were examined. Results indicated that both proinflammatory and antiinflammatory cytokines were significantly higher in tumor-bearing mice than in control mice, and these effects were largest for interleukin-6 (IL-6) and IL-10. Among tumor-bearing mice, significant correlations between IL-1β, IL-6, tumor necrosis factor alpha (TNF-α), transforming growth factor beta (TGF- β) and locomotion were noted, but there was no significant correlation between cytokines and anhedonia. No significant effect of housing condition on cytokines was found. In Chapter 6, principal findings of the project are summarized and discussed with a focus on anhedonia and psychomotor slowing in MDD. Current evidence suggests that dopaminergic and glutamatergic systems in the brain may underlie anhedonic and psychomotor features in inflammation-induced depression. Thus, future investigation of the mediators between ovarian tumor and these depressive-like behaviors in the model may benefit from targeting these specific neural mechanisms.
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13

Hummel, Alexandra Carlyle. "Maternal Depressive Symptoms, Maternal Behavior, and Toddler Internalizing Outcomes: A Moderated Mediation Model." Miami University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=miami1366881153.

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14

Xanthos, Evan D. "Angiotensin-II receptor blocker and its effects on depressive-like behavior during maternal separation." Wright State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=wright1437154659.

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15

Read, Gary Frank Hoyland. "An investigation into the relationship between adolescent parasuicide, depressive illness and associated risk factors." Thesis, Rhodes University, 1996. http://hdl.handle.net/10962/d1004615.

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This study aimed at investigating the relationship between adolescent parasuicide, depressive illness and associated risk factors. Reports worldwide indicate that suicidal behaviour in this age group has risen 150% over the past 20 years, whilst the rate for suicide in adults and the elderly has remained the same (Deykin et al, 1985; Neiger & Hopkins, 1988; Sudak, Ford & Rushforth, 1984a). In South Africa statistics confirm similar trends with regard to attempted and completed suicide. Statistics reveal that a high local incidence of adolescent suicide attempters are seen at psychiatric units. One pilot study recorded 187 adolescent suicide attempters during a three month period. This study was based on the hypothesis that the incidence of depressive illness in adolescent suicide attempters is higher than is generally accepted and that this condition often goes unrecognised and is misdiagnosed because it manifests differently with acting out behaviour and "masked" symptomatology. A random sample of suicide attempters between the ages of 13 - 25 who presented at C23 (psychiatric emergencies) Groote Schuur Hospital following a suicide attempt were assessed. 100 subjects were seen over a period of three months. The research procedure comprised a comprehensive assessment incorporating a semi-structured interview, self-report and objective rating scales for depression as well as instruments designed to assess the general health of each subject and their level of suicide intent. The depressive inventories used have been validated for use in this age group and were designed to elicit the associated features of adolescent depression. If warranted, a clinical diagnoses was given based on DSM 1V criteria. This diagnosis was substantiated by information from the research instruments which formed part of the assessment process. A high incidence of clinical disorders was diagnosed in the sample (86%). Depressive illness was found to be a significant risk factor for suicidal behaviour with 68% of the subjects suffering from an affective disorder and 21% reporting depressive symptoms. This study shows that the correlation between parasuicide and depressive illness is high enough to suggest that all suicidal behaviour in this age group should be taken seriously as parasuicide in itself is often a reliable indicator of an underlying depressive condition. Additional risk factors for adolescent parasuicide identified in this study correlated well with the findings of similar research studies. Psychiatric co-morbidity, especially substance use (42%) and cluster B personality factors (54%), were high and served to increase an individual's vulnerability to suicide risk. Psychosocial factors such as sexual abuse (28%) and physical abuse (37%) were also identified as high risk factors for adolescent suicidal behaviour. Individuals at risk for depression and suicidal behaviour typically came from broken homes which were disrupted and unsupportive. Family members were frequently abusing alcohol and 67% of the subjects reported the presence of psychiatric illness in the family. The preferred method of suicide attempt was an overdose (90%). These attempts were generally unplanned and impulsive with no disclosure prior to the event. Intent was usually high at the time of the act. It is only through identifying the risk factors specific to the developmental concerns of this age group and acknowledging the role of depressive illness in adolescent suicidal behaviour that effective preventative measures can be devised.
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16

Reynolds, Esther, Jessica K. Rabon, Jon R. Webb, Edward C. Chang, and Jameson K. Hirsch. "Domestic Violence and Depressive Symptoms in Primary Care: Role of Forgiveness as a Mediator." Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/614.

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17

Pomp, Sarah [Verfasser]. "The role of depressive symptoms in the process of health behavior change / Sarah Pomp." Berlin : Freie Universität Berlin, 2012. http://d-nb.info/1027815340/34.

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18

Lu, Hsun-Ming. "Current depressive mood, health perception and HIV sexual risk behavior in the mentally ill." Thesis, Boston University, 2012. https://hdl.handle.net/2144/12492.

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Thesis (M.A.)--Boston University PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.
Background and Purpose: The mentally ill population is more susceptible to HIV infections possibly due to impaired mental status resulting in poor insight and judgment in HIV sexual risk behavior. Specifically, depressed mood has been associated with negative effects on health risk perception, as well as increased health risk behavior. Understanding of the decision making process and HIV risk behavior in people with mental illness can help healthcare providers better adjust prevention strategies to address the specific needs of each client. Methods: As part of a main study which aims to prevent HIV in the mentally ill population, this thesis utilized descriptive baseline data collected during the initial stages of the larger study. The first 75 HIV non-positive participants included in the main study were interviewed extensively with regard to their mood, mental status, and risk behaviors. Specifically, the Structured Clinical Interview for DSM-IV (SCID) was used to record current depressed mood, the demographics questionnaire to determine perception of general health and HIV risk, and the Timeline Follow Back (TLFB) method to collect HIV sexual risk behavior activity in the previous 3 months. Results: We found a significant relationship (p = .034) between current depressed mood and poorer general health perception, no relationship (p = .768) between current depressed mood and HIV risk perception, and a trend (0.2 > p = .158) between current depressed mood and HIV sexual risk behavior. Conclusion: Results in this study support the postulation that depressed mood can negatively affect health perception in general. However, it does not support the prediction that depressed mood is associated with perceived HIV specific risk. There is also a trend suggesting that future research should explore the relationship between depressed mood and sexual risk behavior.
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19

Marchand, Jennifer F. "Family predictors of child behavior problems : maternal and paternal depressive symptoms and marital problems /." The Ohio State University, 1998. http://rave.ohiolink.edu/etdc/view?acc_num=osu148795015360342.

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20

Nsamenang, Sheri A., Jon R. Webb, Kelly C. Cukrowicz, and Jameson K. Hirsch. "Depressive Symptoms and Interpersonal Needs as Mediators of Forgiveness and Suicidal Behavior Among Rural Primary Care Patients." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etsu-works/657.

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Background: Suicide is the 10th leading cause of death in the US, and rates of suicide are higher in rural than urban areas. As proposed by the Interpersonal-Psychological Theory of Suicide, thwarted belongingness and perceived burdensomeness are risk factors for suicidal behavior, although protective individual-level characteristics such as forgiveness, may indirectly affect suicidal behavior by decreasing the deleterious effect of thwarted interpersonal needs. Method: A sample of uninsured adults recruited from a rural primary clinic (N=101) completed the Brief Multidimensional Measure of Religiousness and Spirituality; Suicidal Behaviors Questionnaire-Revised; Interpersonal Needs Questionnaire; and Center for Epidemiologic Studies Depression Scale. Parallel and serial multivariable mediation analyses were conducted to test for direct and indirect effects of forgiveness on suicidal behavior. Results: In parallel mediation, covarying depressive symptoms, forgiveness of self had an indirect effect on suicidal behavior, through perceived burdensomeness. Inclusion of depressive symptoms as a mediator revealed an indirect effect of forgiveness of self and others on suicidal behavior via depression, thwarted belongingness, and perceived burdensomeness in a serial mediation model. Limitation: A longitudinal study, with an equal representation of males and diverse populations is needed to replicate our findings. Discussion: Our findings have implications for the role health providers can play in addressing suicide with rural patients. Promoting forgiveness, may, in turn affect interpersonal functioning and decrease risk for suicidal behavior.
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Chang, Edward C., Jiachen Lin, Erin E. Fowler, Elizabeth A. Yu, Tina Yu, Zunaira Jilani, Emma R. Kahle, and Jameson K. Hirsch. "Sexual Assault and Depressive Symptoms in College Students: Do Psychological Needs Account for the Relationship?" Digital Commons @ East Tennessee State University, 2015. https://doi.org/10.1093/sw/swv017.

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In this study, authors examined basic psychological needs (namely, competence, autonomy, and relatedness) as potential mediators of the association between sexual assault and depressive symptoms in a sample of 342 college students. Results from conducting a multiple mediation test provided support for partial mediation involving the indirect effects of competence and autonomy. In contrast, no support for mediation was found involving relatedness. It is notable that sexual assault remained a significant predictor of depressive symptoms in students. Therefore, findings indicate how sexual assault may both directly and indirectly (through psychological needs) lead to greater depressive symptoms in students. Authors concluded the article with a discussion of the implications of their findings for expanding the study of basic psychological needs in college students and the need for greater efforts to prevent and treat sexual assault on campus.
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Hirsch, Jameson K., Kristin L. Walker, Ross B. Wilkinson, and Jeffrey M. Lyness. "Family Criticism and Depressive Symptoms in Older Adult Primary Care Patients: Optimism and Pessimism as Moderators." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/686.

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Objective: Depression is a significant global public health burden, and older adults may be particularly vulnerable to its effects. Among other risk factors, interpersonal conflicts, such as perceived criticism from family members, can increase risk for depressive symptoms in this population. We examined family criticism as a predictor of depressive symptoms and the potential moderating effect of optimism and pessimism. Methods: One hundred five older adult, primary care patients completed self-report measures of family criticism, optimism and pessimism, and symptoms of depression. We hypothesized that optimism and pessimism would moderate the relationship between family criticism and depressive symptoms. Results: In support of our hypothesis, those with greater optimism and less pessimism reported fewer depressive symptoms associated with family criticism. Conclusion: Therapeutic enhancement of optimism and amelioration of pessimism may buffer against depression in patients experiencing familial criticism.
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23

Visser, Preston L., Priya Loess, Elizabeth L. Jeglic, and Jameson K. Hirsch. "Hope as a Moderator of Negative Life Events and Depressive Symptoms in a Diverse Sample." Digital Commons @ East Tennessee State University, 2013. https://doi.org/10.1002/smi.2433.

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Depression is a significant public health problem for young adults of college age, and negative life events exacerbate risk. Not all individuals who experience negative life events, however, report depressive symptoms, perhaps owing to protective characteristics. We examined one such characteristic, trait hope, a goal-oriented construct, as a potential moderator of the association between negative life events and depressive symptoms in an ethnically diverse sample of 386 college students. In support of our hypotheses, negative life events were significantly associated with greater levels of depressive symptoms, and higher levels of hope attenuated this relationship, such that those with greater hope reported fewer depressive symptoms related to potentially traumatic events. The moderating effect of hope did not differ across ethnic groups. Our findings have implications for managing the sequelae of negative life events, including depression. Cognitive–behavioural interventions tailored to help young adults identify and attain important life goals might help to overcome psychopathology associated with life stress. Copyright © 2012 John Wiley & Sons, Ltd.
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24

Chang, Edward C., Olivia D. Chang, Elizabeth A. Yu, Kaidi Wu, Abigael G. Lucas, P. Priscilla Lui, David Rollock, Xinjie Chen, and Jameson K. Hirsch. "How Future Orientation is Associated with Depressive Symptoms in Multiethnoracial Adults: Basic Psychological Needs as a Mediator." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/etsu-works/5496.

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We examined the role of basic psychological needs as a mediator of the association between future orientation and depressive symptoms in a sample of 202 (159 female and 43 male) multiethnoracial adults. Multiple mediation analysis with 10,000 bootstraps was conducted to test for mediation. The association between future orientation and depressive symptoms was found to be accounted for by dimensions of basic psychological needs. Specifically, future orientation was negatively related to depressive symptoms through positive associations involving autonomy and competence, but not relatedness. The present findings are the first to not only point to the importance of examining future orientation in understanding depressive symptoms in multiethnoracial adults, but they are also the first to suggest possible mechanisms by which believing in a changeable future might foster stronger satisfaction of basic psychological needs, especially autonomy and competence, that might help multiethnoracials garner greater protection when encountering stressful situations in their lives.
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Hirsch, Jameson K., Tracy J. Cohn, Catherine A. Rowe, and Sarah E. Rimmer. "Minority Sexual Orientation, Gender Identity Status and Suicidal Behavior: Serial Indirect Effects of Hope, Hopelessness and Depressive Symptoms." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/848.

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Death by suicide, and suicidal behaviors, are a significant public mental health problem, and individuals who are lesbian, gay, bisexual, transgendered and questioning (LGBTQ), may be at increased risk. Potential underlying mechanisms of this association are unknown, but may involve the impact of LGBTQ status on future orientation and mood. Our purpose was to determine the influence of sexual identity, sequentially, on cognitive and emotional functioning, and consequent relation to suicidal behavior. In a sample of 349 college students, we used serial mediation models to investigate the relation between self-identification as LGBTQ and suicidal behavior, with hope and hopelessness as first-order mediators and depression as a second order mediator. Supporting hypotheses, we found that LGBTQ status was related to less hope and greater hopelessness and, in serial fashion, to depressive symptoms and consequent suicidal behavior. Our findings may have clinical implications. Resolution of hopelessness and depression, and promotion of hopefulness, perhaps via Motivational Interviewing and Cognitive Behavioral Therapy strategies, such as goal-setting, may reduce suicidal risk in LGBTQ young adults.
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26

Belton, Allyson S. "Access to Mental Healthcare and Help-seeking Behaviors among African American Women with Depressive Symptoms in a Community-based Primary Healthcare Center." Digital Archive @ GSU, 2013. http://digitalarchive.gsu.edu/iph_theses/278.

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Mental illness is a significant contributor to the global burden of disease. As public health practitioners, we must generate more than sufficient knowledge about mental health and illness in order to identify risk factors, increase awareness, improve treatment, eliminate the overall disparity associated with mental illness, and improve access to care to all affected, including those disproportionally affected by mental illness. Over time, there has been an overall lack of sufficient research studies on depression among African American women. As research in this area grows, it is critical to examine the underlying causative factors that are correlated with this disease and this population in order to provide better treatment options and a global understanding. This project will examine and analyze data obtained from the study assessment as it relates to psychosocial factors as reported by the study participants and generate a conclusion based on these findings. Additionally, this project will look to determine the help‐seeking behaviors of these women with access to a primary care physician and/or clinic. Overall, findings from this thesis project will provide an understanding of the specific psychosocial variables affecting African American women with depression and depressive symptoms, as well as provide an understanding of the help‐seeking behaviors of African American women, and contribute to the improvement of research in mental health in the United States.
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Gabella, Kristin. "THE MECHANISMS BY WHICH REPEATED STRESS EXPOSURE ALTERS BRAIN CYTOKINES: IMPLICATIONS FOR DEPRESSIVE-LIKE BEHAVIOR." Kent State University Honors College / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=ksuhonors1367676963.

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28

Reis-Silva, Thiago M. "Efeitos transgeracionais da administração pré-natal do lipopolissacarídeo sobre o comportamento e sistema imune de camundongos avaliados por modelos de depressão." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/47/47135/tde-15082013-094938/.

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A depressão é hoje a doença mental mais comum do mundo, afetando mais de 121 milhões de pessoas. Além disso, estima-se que em aproximadamente uma década ela se torne a 2º doença responsável pela perda prematura de vida entre todas as idades e sexos. Diferentes propostas foram feitas no intuito de se compreender os mecanismos pelos quais essa doença incide, contudo a etiologia dos transtornos depressivos ainda não é totalmente entendida. Existem consideráveis evidências de que a administração perinatal de lipopolissacarídeo (LPS), uma endotoxina bacteriana, promove efeitos persistentes no desenvolvimento e comportamento da prole de camundongos, os quais podem-se manter até a idade adulta. Ainda, esses eventos podem ter implicações evolucionárias ligadas a alterações transgeracionais. Tendo em vista que a ativação do sistema imune pode estar relacionada com os transtornos depressivos, o presente trabalho expos pré-natalmente ao LPS uma geração de camundongos avaliando os efeitos comportamentais dessa exposição em três gerações subsequentes levando-se em consideração os comportamentos depressivos e não depressivos de cada geração avaliada. Para isso camundongos fêmeas, após terem o comportamento selecionado pelo teste de suspensão da cauda (TSC), foram cruzadas com machos de mesmo comportamento recebendo 100g/kg de LPS ou solução salina no 15º dia de prenhez. Após os nascimentos, as gerações subsequentes tiveram o comportamento em questão avaliado pelo TSC, bem como a atividade geral em campo aberto. Além disso, a interação materno-filhote foi avaliada, uma vez que alterações na mesma poderiam contribuir para os efeitos do tratamento com a endotoxina. Ainda, foi-se realizado um desafio com LPS na geração filial 3, na qual o nível de citocinas e a expressão do comportamento doentio foram avaliadas. Os resultados mostraram que (i) a administração do LPS na geração parental não afetou o comportamento depressivo e não depressivo nas três gerações avaliadas, dado que animais com comportamento depressivo tiveram mais filhotes com o mesmo comportamento em todas as gerações. (ii) Foram observadas alterações no comportamento materno da geração parental, possivelmente ligadas a motivação materna desses animais. (iii) Foram encontradas alterações transgeracionais na atividade geral de camundongos machos e fêmeas das gerações filiais 1 e 2. Tais alterações foram mais x expressivas nos machos e, havendo diferenças entre o comportamento. Esses dados apontam que a exposição a endotoxina possui diferentes consequências de acordo com o comportamento e, (iv) os animais da geração filial 3 quando desafiados com a endotoxina apresentaram maior comportamento doentio e maiores níveis de citocinas. Esses dados apontam para um forte componente genético na transmissão do comportamento, além de, uma influencia epigenética na modulação do mesmo. Ainda, foi possível concluir que a inflamação gerada pela administração pré-natal do LPS atua de forma distinta entre os sexos, bem como o histórico comportamental, no caso, o comportamento depressivo e não depressivo estudados nesse trabalho
Depression disorders are to be considered the most common mental illness affecting more than 121 million people worldwide. It is estimated that approximately one decade it becomes the 2nd disease most responsible for premature loss of life of all ages and sexes. Different proposals to understand this disorders have been made in the past years, however its etiology it is still yet fully understood. There is considerable evidence that the administration of lipopolysaccharide (LPS), a bacterial endotoxin, promotes persistent effects on development and behavior of the offspring of mice, which are maintained into adulthood. Still, these events may have evolutionary implications related to transgenerational changes. Given that activation of the immune system may be related to depressive disorders, this study aimed to expose a generation of mice to LPS evaluating the behavioral effects on three subsequent generations taking into account the depressive-like and non depressive-like behaviors assessed on each generation by the tail suspension test (TST). For this, female mice after behavior selected by the tail suspension test (TST) were crossed with males of the same behavior and exposed to 100g/kg of LPS or saline solution on day 15th of pregnancy. After births, the subsequent generations were also evaluated on the TST and in the open field for general activity. In addition, the maternal interaction was also evaluated, since changes on this parameter could contribute to the treatment effects of the endotoxin. Yet, has been performed a challenge with LPS in the generation branch 3, wherein the level of expression of cytokines and sickness behavior were evaluated. The results showed that (i) the administration of LPS in the parental generation did not affect the depressive-like behaviors on the three generations evaluated, since animals with depressive-like and non depressive-like behavior had more offspring with the same behavior in all generations. (ii) Changes were observed in maternal behavior of the parental generation which is possibly related to a change in motivational state of those animals. (iii) Transgenerational alterations were found in the general activity of male and female mice of the filial generation 1 and 2. These changes were more significant in males and differences between depressive-like e non depressive-like behaviors were also observed. Together, these data indicate that the exposure to endotoxin has different consequences according to the animal historical behavior and, xii finally, (iv) the animals of filial generation 3 when challenged with endotoxin had higher sickness behavior and higher levels of cytokines when evaluated in the open field test. These data point to a strong genetic component in the transmission of behavior and, besides, a possible influence of epigenetic mechanism of the same. Furthermore it was possible to concluded that inflammation state created by the prenatal LPS exposure acts differently according to the animal historical behavior, in this case, the depressive-like and non depressive-like behavior studied, and also acting differently according to the sexes
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Chang, Edward C., Tina Yu, Olivia D. Chang, and Jameson K. Hirsch. "Hope and Trauma: Examining a Diathesis-Stress Model in Predicting Depressive and Anxious Symptoms in College Students." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/858.

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The present study sought to examine a diathesis-stress model involving hope and trauma history as predictors of depressive and anxious symptoms in a sample of 575 college students. Results from regression analyses indicated that hope and trauma were important and unique predictors of both depressive and anxious symptoms in students. Moreover, we found support for a significant Hope×Trauma interaction in predicting both depressive and anxious symptoms. Some implications of the present findings are discussed.
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Hirsch, Jameson K., Fuschia M. Sirois, and Edward C. Chang. "Pain and Depressive Symptoms in Primary Care Patients: Moderating Role of Positive and Negative Affect." Digital Commons @ East Tennessee State University, 2012. https://dc.etsu.edu/etsu-works/605.

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Pech, Alexandria Sarissa, and Alexandria Sarissa Pech. "Associations Between Parental Depressive Symptoms, Coparenting, and Behavior Outcomes in Young Children with Previously Incarcerated Fathers." Thesis, The University of Arizona, 2017. http://hdl.handle.net/10150/624123.

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The purpose of the study is to examine young children's internalizing and externalizing behaviors in the context of post paternal incarceration by focusing on both risks (i.e., parental depressive symptoms), protective factors (i.e., coparenting alliance), and their impact considered together. The final sample included 426 previously incarcerated fathers and the biological mothers of their three-year-old children. Using hierarchical multiple regression, I examined three sets of analyses: 1) the association between parental depressive symptoms and children's behavior outcomes, 2) the association between coparenting alliance and children's behavior, 3) the association between parental depressive symptoms and children's behavior as moderated by coparenting alliance. Expectedly, higher paternal depressive symptoms were associated with higher externalizing behavioral problems in children. Unexpectedly, higher maternal depressive symptoms were associated with lower externalizing behavioral problems. Also, unexpectedly, the associations between maternal and paternal coparenting alliance and both child behavioral outcomes were not statistically significant. Further, when mothers reported lower coparenting alliance with their child's father, the negative association between fathers' depressive symptoms and children’s internalizing behavioral problems was not attenuated; in fact, children had higher internalizing behavioral problems. My findings suggests father's depressive symptoms are an important point of consideration given the deleterious effects parental depressive symptoms can have on children, and the risks for depressive symptoms among formerly incarcerated fathers. Further, my findings have implications for addressing and treating fathers' depressive symptoms when children are relatively young in order to lower internalizing behavior problems from persisting across and beyond childhood.
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Hatfield, Joshua P., Jameson K. Hirsch, and Jeffrey M. Lyness. "Functional Impairment, Illness Burden, and Depressive Symptoms in Older Adults: Does Type of Social Relationship Matter?" Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etsu-works/687.

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Objective: The nature of interpersonal relationships, whether supportive or critical, may affect the association between health status and mental health outcomes. We examined the potential moderating effects of social support, as a buffer, and family criticism, as an exacerbating factor, on the association between illness burden, functional impairment and depressive symptoms. Methods: Our sample of 735 older adults, 65 years and older, was recruited from internal and family medicine primary care offices. Trained interviewers administered the Hamilton Rating Scale for Depression, Duke Social Support Inventory, and Family Emotional Involvement and Criticism Scale. Physician-rated assessments of health, including the Karnofsky Performance Status Scale and Cumulative Illness Rating Scale, were also completed. Results: Linear multivariable hierarchical regression results indicate that social interaction was a significant buffer, weakening the association between illness burden and depressive symptoms, whereas perceived social support buffered the relationship between functional impairment and depressive symptoms. Family criticism and instrumental social support were not significant moderators. Conclusions: Type of medical dysfunction, whether illness or impairment, may require different therapeutic and supportive approaches. Enhancement of perceived social support, for those who are impaired, and encouragement of social interactions, for those who are ill, may be important intervention targets for treatment of depressive symptoms in older adult primary care patients.
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Nsamenang, Sheri A., Jameson K. Hirsch, Raluca Topciu, Andrew D. Goodman, and Paul R. Duberstein. "The Interrelations Between Spiritual Well-Being, Pain Interference and Depressive Symptoms in Patients with Multiple Sclerosis." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/695.

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Depressive symptoms are common in individuals with multiple sclerosis (MS), and are frequently exacerbated by pain; however, spiritual well-being may allow persons with MS to more effectively cope with pain-related deficits in physical and role functioning. We explored the associations between spiritual well-being, pain interference and depressive symptoms, assessing each as a potential mediator, in eighty-one patients being treated for MS, who completed self-report measures: Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being Scale, Pain Effects Scale, and Center for Epidemiologic Studies Depression Scale Revised. At the bivariate level, spiritual well-being and its subscale of meaning and peace were negatively associated with depression and pain interference. In mediation models, depression was not related to pain interference via spiritual well-being, or to spiritual well-being via pain interference. Pain interference was related to depression via spiritual well-being and meaning/peace, and to spiritual well-being and meaning/peace via depressive symptoms. Finally, spiritual well-being and meaning/peace were related to depression via pain interference, and to pain interference via depressive symptoms. For patients with MS, a multi-faceted approach to treatment that includes pain reduction and promotion of spiritual well-being may be beneficial, although amelioration of depression remains a critical task.
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Chang, Edward C., Elizabeth A. Yu, Tina Yu, Emma R. Kahle, Viviana Hernandez, Jean M. Kim, Elizabeth L. Jeglic, and Jameson K. Hirsch. "Ethnic Variables and Negative Life Events as Predictors of Depressive Symptoms and Suicidal Behaviors in Latino College Students: On the Centrality of Receptivo a los Demás." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/857.

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In the present study, we examined ethnic variables (viz., multigroup ethnic identity and other group orientation) along with negative life events as predictors of depressive symptoms and suicidal behaviors in a sample of 156 (38 male and 118 female) Latino college students. Results of conducting hierarchical regression analyses indicated that the set of ethnic variables accounted for significant variance in both depressive symptoms and suicidal behaviors. The inclusion of negative life events was found to account for significant additional variance in both outcomes, beyond what was accounted for by ethnic variables. Interestingly, beyond main effects, results indicated a significant Other Group Orientation × Negative Life Events interaction effect to account for additional variance in depressive symptoms and suicidal behaviors. Some implications of the present findings are discussed, including the potential value for Latinos to broaden their attitudes and interactions with other ethnic groups.
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Muyan, Mine, Edward C. Chang, Zunaira Jilani, Tina Yu, Jiachen Lin, and Jameson K. Hirsch. "Loneliness and Negative Affective Conditions in Adults: Is There Any Room for Hope in Predicting Anxiety and Depressive Symptoms?" Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/661.

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This study examined the role of hope in understanding the link between loneliness and negative affective conditions (viz., anxiety and depressive symptoms) in a sample of 318 adults. As expected, loneliness was found to be a significant predictor of both anxiety and depressive symptoms. Noteworthy, hope was found to significantly augment the prediction of depressive symptoms, even after accounting for loneliness. Furthermore, we found evidence for a significant Loneliness × Hope interaction effect in predicting anxiety. A plot of the interaction confirmed that the association between loneliness and anxiety was weaker among high, compared to low, hope adults. Some implications of the present findings are discussed.
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Lamis, Dorian A., Jameson K. Hirsch, Kelley C. Pugh, Raluca Topciu, Sheri A. Nsamenang, Andrew Goodman, and Paul R. Duberstein. "Perceived Cognitive Deficits and Depressive Symptoms in Patients with Multiple Sclerosis: Perceived Stress and Sleep Quality as Mediators." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/etsu-works/2789.

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Multiple Sclerosis (MS), an autoimmune disorder marked by inflammation of the central nervous system, is associated with a myriad of symptoms. Individuals with MS are more likely to experience depressive symptoms, perhaps due to perceived cognitive impairments. Thus, we aimed to explore perceived stress and sleep deficits as potential mediators of the association between perceived cognitive deficits and depressive symptoms. We recruited a sample of 77 MS participants from an outpatient, university-based MS clinic in the United States. Participants ranged in age between 30 and 75 years old (M = 51.12; SD = 9.6), with more females than males (83% female; n = 64). Participants completed the Perceived Deficits Questionnaire, the Pittsburgh Sleep Quality Index, the Perceived Stress Scale, and the Center for Epidemiological Studies Depression Scale – Revised. Correlation analyses and mediation analyses were conducted with bootstrapping technique. Statistical analyses revealed that higher levels of perceived cognitive deficits were associated with lower quality of sleep, more perceived stress, and higher levels of depressive symptoms. Additionally, both perceived stress and sleep quality served as a significant mediator in the perceived cognitive impairments and depressive symptoms linkage. Our novel findings demonstrate the importance of underlying mechanisms (e.g., sleep quality and perceived stress) in the conceptualization of MS. Perceived stress and sleep quality are potentially modifiable factors, perhaps serving as a target for future treatment, to buffer risk of MS patients developing depression.
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Pearl, Erica S. "Depressive Symptoms and Prosocial Behavior in Elementary School Students after Participating in an Anti-Bullying Program." Xavier University / OhioLINK, 2003. http://rave.ohiolink.edu/etdc/view?acc_num=xavier1383573742.

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38

Chang, Edward C., Zunaira Jilani, Erin E. Fowler, Tina Yu, Shao Wei Chia, Elizabeth A. Yu, Hannah K. McCabe, and Jameson K. Hirsch. "The Relationship Between Multidimensional Spirituality and Depressive Symptoms in College Students: Examining Hope Agency and Pathways as Potential Mediators." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/690.

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In this study, we examined goal-focused hope as a potential mediator between the association of multidimensional spirituality and depressive symptoms in a sample of 319 college students. Results of conducting a series of multiple mediation tests indicated that hope agency, but not hope pathways, fully and significantly accounted for the associations of ritualistic, theistic, and existential spirituality with depressive symptoms. Overall, our findings offer support for the contention that hope agency plays an important role in accounting for the association between spirituality and psychological adjustment in college students. Some implications of the present findings are discussed.
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Nemcek, Laura A. "The Mood and Behavior Rating Scale for Youth - Parent Form (MBRSY-PF) : a parent informant questionnaire to assess for bipolar disorder in children and adolescents /." Online version of thesis, 2008. http://hdl.handle.net/1850/6298.

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40

Leas, Loranie, and mikewood@deakin edu au. "Cardiovascular health behaviours and health needs among people with psychiatric disabilities." Deakin University. School of Psychology, 2004. http://tux.lib.deakin.edu.au./adt-VDU/public/adt-VDU20051208.095530.

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Recent research in Australia has found that people with a mental illness experience higher mortality rates from preventable illnesses, such as cardiovascular disease, respiratory disease and diabetes compared to the general population. Lifestyle and other behavioural factors contribute significantly to these illnesses. Lifestyle behaviours that affect these illnesses include lack of physical activity, consumption of a poor diet and cigarette smoking. Research on the influence of these factors has been mainly directed towards the mainstream population in Australia. Consequently, there remains limited understanding of health behaviours among individuals with psychiatric disabilities, their health needs, or factors influencing their participation in protective health behaviours. This thesis presents findings from two studies. Study 1 evaluated the utility of the main components of Roger’s (1983) Protection Motivation Theory (PMT) to explain health behaviours among people with a mental illness. A clinical population of individuals with schizophrenia (N=83), Major Depressive Disorder (MDD) (N=70) and individuals without a mental illness (N=147) participated in the study. Respondents provided information on intentions and self-reported behaviour of engaging in physical activity, following a low-fat diet, and stopping smoking. Study 2 investigated the health care service needs of people with psychiatric disabilities (N=20). Results indicated that the prevalence of overweight, cigarette smoking and a sedentary lifestyle were significantly greater among people with a mental illness compared to that reported for individuals without a mental illness. Major predictors of the lack of intentions to adopt health behaviours among individuals with schizophrenia and MDD were high levels of fear of cardiovascular disease, lack of knowledge of correct dietary principles, lower self-efficacy, a limited social support network and a high level of psychiatric symptoms. In addition, findings demonstrated that psychiatric patients are disproportionately higher users of medical services, but they are under-users of preventive medical care services. These differences are primarily due to a lack of focus on preventive health, feelings of disempowerment and lower satisfaction of patient-doctor relationships. Implications of these results are discussed in terms of designing education and preventive programs for individuals with schizophrenia and MDD.
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Jeri-Yabar, Antoine, Alejandra Sanchez-Carbonel, Karen Tito, Jimena Ramirez-delCastillo, Alessandra Torres-Alcantara, Daniela Denegri, and Nilton Yhuri Carreazo. "Association between social media use (Twitter, Instagram, Facebook) and depressive symptoms: Are Twitter users at higher risk?" SAGE Publications Ltd, 2019. http://hdl.handle.net/10757/625046.

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El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.
Background: The purpose of this study was to determine the association between social media dependence and depressive symptoms and also, to characterize the level of dependence. It was a transversal, analytical research. Subjects and Methods: The stratified sample was 212 students from a private university that used Facebook, Instagram and/or Twitter. To measure depressive symptoms, Beck Depression Inventory was used, and to measure the dependence to social media, the Social Media Addiction Test was used, adapted from the Internet Addiction Test of Echeburúa. The collected data were subjected for analysis by descriptive statistics where STATA12 was used. Results: The results show that there is an association between social media dependence and depressive symptoms (PR [Prevalence Ratio] = 2.87, CI [Confidence Interval] 2.03–4.07). It was also shown that preferring the use of Twitter (PR = 1.84, CI 1.21–2.82) over Instagram (PR = 1.61, CI 1.13–2.28) is associated with depressive symptoms when compared to the use of Facebook. Conclusion: Excessive social media use is associated with depressive symptoms in university students, being more prominent in those who prefer the use of Twitter over Facebook and Instagram.
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42

Hooper, Emma G. "Maternal Emotion Expression, Depressive Symptoms, and Stress: Profiles in Relation to Child Emotion Socialization and Problem Behavior." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1374094882.

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43

Schreibeis, Amanda Danielle. "Cross Sensitization of Depressive-Like Behavior through Two Depression Related Paradigms: Maternal Separation and Its Effect on the Forced Swim Test In the Guinea Pig." Wright State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=wright1484638271891606.

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44

Hirsch, Jameson K., Preston L. Visser, Edward C. Chang, and Elizabeth L. Jeglic. "Race and Ethnic Differences in Hope and Hopelessness as Moderators of the Association Between Depressive Symptoms and Suicidal Behavior." Digital Commons @ East Tennessee State University, 2012. https://dc.etsu.edu/etsu-works/656.

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Objective: The authors examined trait hope and hopelessness as potential moderators of the association between depressive symptoms and suicidal behavior. Participants: A diverse sample of 372 college students. Methods: Depressive symptoms, hopelessness (Beck Hopelessness Scale), trait hope (Trait Hope Scale), and suicidal behaviors were assessed. Trait hope is defined as confidence in the ability to identify and attain goals, whereas hopelessness encompasses future attitudes and motivation loss. Results: In independent models, low hopelessness buffered the association between depressive symptoms and suicidal behavior for our whole sample, blacks, and whites, whereas trait hope buffered for Hispanics and whites. Examined simultaneously, hope remained a significant moderator only in whites and hopelessness only in blacks. These findings suggest that etiological and outcome correlates of hope and hopelessness may differ by ethnicity. Conclusions: These findings may have implications for development of culturally targeted interventions for college students that strive to simultaneously reduce hopelessness and bolster hopefulness.
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45

Lee, Jerin, Edward C. Chang, Abigael G. Lucas, and Jameson K. Hirsch. "Academic Motivation and Psychological Needs as Predictors of Suicidal Risk." Digital Commons @ East Tennessee State University, 2019. https://doi.org/10.1002/jocc.12123.

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This study examined academic motivation and basic psychological needs as predictors of suicidal risk (namely, depressive symptoms and suicidal behaviors) in a sample of 348 college students. Results from regression analyses indicated that academic motivation was a significant predictor of suicidal risk. The inclusion of basic psychological needs significantly augmented the prediction model. The authors discuss implications for considering academic motivation and basic psychological needs in college counseling on the basis of the results.
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46

Sander, Amy Janay Boswell. "Toward an integration of Beck's cognitive theory and Bowlby's attachment theory : self-schema and adult attachment classification in relation to depressive symptoms /." Access restricted to users with UT Austin EID Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3035975.

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47

Chang, Edward C., Emma R. Kahle, Elizabeth A. Yu, Jenny Y. Lee, Yvonne Kupfermann, and Jameson K. Hirsch. "Relations of Religiosity and Spirituality with Depressive Symptoms in Primary Care Adults: Evidence for Hope Agency and Pathway as Mediators." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etsu-works/864.

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This study examined hope agency and pathway as potential mediators of the associations of religiosity and spirituality with depressive symptoms in an adult sample of 101 primary care adults. Results of conducting multiple mediation tests indicated that hope agency and pathway fully and significantly accounted for the associations of religiosity and spirituality with depressive symptoms. In contrast, an alternative mediation model involving religiosity and spirituality as potential mediators of the associations of hope agency and pathway with depressive symptoms failed to be supported. Overall, our findings offer support for the contention that hope agency and pathway play important roles in accounting for the associations of religiosity and spirituality with psychological adjustment in adults. Some implications of the present findings are discussed.
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48

Sirois, Fuschia M., and Jameson K. Hirsch. "Associations of Psychological Thriving with Coping Efficacy, Expectations for Future Growth, and Depressive Symptoms Over Time in People with Arthritis." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etsu-works/865.

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Objective: Psychological thriving reflects a trajectory of growth over time as opposed to scaling back expectations. Whether thriving is a product, precursor, or process of coping with arthritis-related limitations is unclear. We examined associations between thriving, coping efficacy, and expectations for future growth in individuals with arthritis, and the relations of thriving to depressive symptoms and retrospective perceptions of personal growth over a six-month period. Methods: A sample of 423 people with arthritis completed measures of thriving, coping efficacy, depressive symptoms, and expectations for future growth; 168 individuals completed a six-month follow-up survey. Structural equation modeling analyses compared three possible models of psychological thriving, controlling for disease-related variables. Hierarchical regression analyses of the cross-lagged associations of thriving with retrospective perceptions of positive personal change and depressive symptoms were also conducted. Results: Structural equation analyses suggest that the process model in which thriving and coping efficacy jointly predicted expectations for future growth best fit the data. Baseline thriving was also associated with retrospective perceptions of personal growth at follow-up and fewer depressive symptoms at baseline and follow-up, after controlling for disease-related variables. Conclusion: Overall, these findings suggest that psychological thriving is synergistically related to coping efficacy, and to expectations for future growth and less depression, in people with arthritis. Importantly, our findings support the notion that psychological thriving is more than scaling back expectations, and that thriving may be an important quality to cultivate to address the burden of depression in people with arthritis.
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Hirsch, Jameson K., Sheri A. Nsamenang, Edward C. Chang, and Nadine J. Kaslow. "Spiritual Well-Being and Depressive Symptoms in Female African American Suicide Attempters: Mediating Effects of Optimism and Pessimism." Digital Commons @ East Tennessee State University, 2014. https://doi.org/10.1037/a0036723.

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Spiritual well-being is a well-established predictor of mental health, yet the potential mechanisms of this association are relatively unexplored. We examined the influence of spirituality, including religious and existential well-being, on depressive symptoms, and the potential mediating effect of optimism and pessimism, in a sample of 66 African American female suicide attempters. Participants were recruited from a large, urban hospital and completed the Spiritual Well-Being Scale, Life Orientation Test-Revised, and the Beck Depression Inventory-II. The association between spiritual well-being and depressive symptoms was mediated indirectly through both optimism and pessimism; greater religious and existential well-being was related to more optimism, and less pessimism and, in turn, to fewer depressive symptoms. Historically, spiritual well-being has been important to the African American community, and its beneficial effects on mental health might be explained, in part, by their effect on cognitive-emotional functioning.
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Alexander, Vincent Rasahd. "The Role of Corticotropin-Releasing Factor in the Behavior and Proinflammatory Activity of Separated Guinea Pig Pups." Wright State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=wright1345847290.

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