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Relevant bibliographies by topics / Derivatives of hydantoin

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Academic literature on the topic 'Derivatives of hydantoin'

Author: Grafiati

Published: 4 June 2021

Last updated: 18 February 2022

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Journal articles on the topic "Derivatives of hydantoin"

1

López-López, Lluvia Itzel, Denisse de Loera, Ernesto Rivera-Avalos, and Aidé Sáenz-Galindo. "Green Synthesis of Hydantoins and Derivatives." Mini-Reviews in Organic Chemistry 17, no. 2 (2020): 176–84. http://dx.doi.org/10.2174/1570193x16666181206100225.

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The hydantoin moiety is found in several bioactive compounds with important pharmacological properties such as antimicrobial, antifungal, anti-androgens, anticancer and the historical action anticonvulsant. Because of these reasons, the synthesis of these compounds and their derivatives is important to review considering the philosophy of the green chemistry. In this review, we present the actual importance in the green synthesis of hydantoins and their derivatives using green methods, such as microwave and ultrasound irradiation, ionic liquids, solid-phase and solvent-free synthesis. Finally,

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2

Yu, Fang-Lei, Carl H. Schwalbe, and David J. Watkin. "Hydantoin and hydrogen-bonding patterns in hydantoin derivatives." Acta Crystallographica Section C Crystal Structure Communications 60, no. 10 (2004): o714—o717. http://dx.doi.org/10.1107/s0108270104017706.

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3

ASAKAWA, Takanobu, and Somei YARITA. "Noncyanide Silver Plating Solution Using Hydantoin and Hydantoin Derivatives." Journal of the Surface Finishing Society of Japan 50, no. 1 (1999): 68–71. http://dx.doi.org/10.4139/sfj.50.68.

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4

Hanessian, Stephen, Rui-Yang Yang, and Jean-Yves Sancéau. "Synthesis of 1-N-hydroxyhydantoin 5-phosphates as potential fungicides." Canadian Journal of Chemistry 75, no. 6 (1997): 712–15. http://dx.doi.org/10.1139/v97-085.

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Two hydantoin analogs were synthesized utilizing an organometallic allylation reaction in aqueous solution as a key step. One of the derivatives showed weak fungicidal activity. Keywords: hydantoin, fungicide, phosphate.

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5

Divjak, Natalija, Nebojsa Banjac, Natasa Valentic, and Gordana Uscumlic. "Synthesis, structure and solvatochromism of 5-methyl-5-(3-or 4-substituted phenyl)hydantoins." Journal of the Serbian Chemical Society 74, no. 11 (2009): 1195–205. http://dx.doi.org/10.2298/jsc0911195d.

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Several 5-methyl-5-(3- or 4-substituted phenyl)hydantoins were prepared and their ultraviolet absorption spectra were recorded in the region 200-400 nm in twelve solvents of different polarity. The effect of solvent dipolarity/ polarizability and solvent/solute hydrogen bonding interactions were analyzed by means of the linear solvation energy relationship (LSER) concept proposed by Kamlet and Taft. The lipophilic activity of the investigated hydantoins was estimated by calculation of log P values with Advanced Chemistry Development Software. The calculated values of log P were correlated with

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6

Trisovic, Nemanja, Gordana Uscumlic, and Slobodan Petrovic. "Hydantoins: Synthesis, properties and anticonvulsant activity." Chemical Industry 63, no. 1 (2009): 17–31. http://dx.doi.org/10.2298/hemind0901017t.

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Hydantoin is a five-membered cyclic ureide that is present in numerous biologically active compounds including antiarrhytmics, anticonvulsants and antitumor agents. This paper describes different ways of synthesis of hydantoin-derivatives, their physical properties and reactivity. Also, the most widely used hydantoin anticonvulsants and the analysis of structureactivity relationships of anticonvulsant drugs in terms of lipophilicity and hydrogen bonding are presented here.

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7

Kaválek, Jaromír, Vladimír Macháček, Gabriela Svobodová, and Vojeslav Štěrba. "Base catalyzed cyclization of substituted esters of hydantoic and thiohydantoic acids." Collection of Czechoslovak Chemical Communications 51, no. 2 (1986): 375–90. http://dx.doi.org/10.1135/cccc19860375.

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Base catalyzed cyclization rates have been measured of 22 derivatives of hydantoic and thiohydantoic acid esters in water and methanol. The cyclization of methyl and ethyl esters of hydantoic and 5-methylhydantoic acids is accompanied by hydrolysis of the ester group, whereas with the other derivatives the hydrolysis does not take place. Hydrolysis of the cyclization products (hydantoin and thiohydantoin derivatives) is not significant under the kinetic conditions. The cyclization of methyl ester of 5-phenylhydantoic acid in methanol is reversible; the equilibrium mixture contains 30% of the s

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8

Abadi, Ashraf H., Jochen Lehmann, Gary A. Piazza, Mohammad Abdel-Halim та Mohamed S. M. Ali. "Synthesis, Molecular Modeling, and Biological Evaluation of Novel Tetrahydro-β-Carboline Hydantoin and Tetrahydro-β-Carboline Thiohydantoin Derivatives as Phosphodiesterase 5 Inhibitors". International Journal of Medicinal Chemistry 2011 (23 лютого 2011): 1–9. http://dx.doi.org/10.1155/2011/562421.

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Two series of fused tetrahydro-β-carboline hydantoin and tetrahydro-β-carboline thiohydantoin derivatives with a pendant 2,4-dimethoxyphenyl at position 5 were synthesized, and chiral carbons at positions 5 and 11a swing from R,R to R,S, S,R, and S,S. The prepared analogues were evaluated for their capacity to inhibit phosphodiesterase 5 (PDE5) isozyme. The R absolute configuration of C-5 in the β-carboline hydantoin derivatives was found to be essential for the PDE5 inhibition. Chiral carbon derived from amino acid even if of the S configuration (L-tryptophan) may lead to equiactive or more a

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9

Ahmad, Roshan, Rukhsana Jabeen, Mohammad Zia-ul-Haq, Humaira Nadeem, Helmut Duddeck, and Eugen J. Verspohl. "Chiral Aryl Sulfonyl Hydantoins as Hypoglycemic Agents." Zeitschrift für Naturforschung B 55, no. 2 (2000): 203–7. http://dx.doi.org/10.1515/znb-2000-0212.

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Some novel chiral sulfonyl hydantoin derivatives 2a-e and 3 a-e have been prepared. p-Toluenesulfonyl chloride on treatment with L-amino acids in presence of K2CO3/H2O yielded N-(p-toluensulfonyl-)amino acids 1a - e which were cyclized in presence of NH4-SCN Ac2O to afford 1-(p-toluenesulfonyl)-5-substituted-2-thiohydantoins 2a-e. These compounds were oxidized with HNO3 to yield 1-(p-toluenesulfonyl)-5-substituted hydantoins 3a-e. The enantiomeric ratios of 3a-e were determined by 1H NMR spectroscopy using Eu(hfc)3. The antidiabetic activity of 3a-d has been determined.

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10

Lazic, Anita, Natasa Valentic, Nemanja Trisovic, Slobodan Petrovic, and Gordana Uscumlic. "Synthesis, structure and biological properties of active spirohydantoin derivatives." Chemical Industry 70, no. 2 (2016): 177–99. http://dx.doi.org/10.2298/hemind150205025l.

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Spirohidantoins represent an pharmacologically important class of heterocycles since many derivatives have been recognized that display interesting activities against a wide range of biological targets. First synthesis of cycloalkanespiro-5-hydantoins was performed by Bucherer and Lieb 1934 by the reaction of cycloalkanone, potassium cyanide and ammonium-carbonate at reflux in a mixture of ethanol and water. QSAR (Quantitative Structure-Activity Relationship) studies showed that a wide range of biological activities of spirohydantoin derivatives strongly depend upon their structure. This paper

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Dissertations / Theses on the topic "Derivatives of hydantoin"

1

Howie, Colin. "The design, synthesis and testing of hydantoin derivatives as inhibitors of pyrimidine biosynthesis." Thesis, University of Glasgow, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.278514.

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2

EVARISTO, Miguel do Rosário. "Biological activity of well defined hydantoin derivatives on efflux pump systems of bacteria and cancer cells." Master's thesis, Instituto de Higiene e Medicina Tropical, 2010. http://hdl.handle.net/10362/5617.

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A multi-resistência a antibióticos e medicamentos usados em quimioterapia é um dos grandes problemas com os quais as instituições de saúde se debatem hoje em dia. A acção provocada por bombas de efluxo é uma das suas causas. Estas bombas têm uma importância fundamental, uma vez que, ao expelirem todo o tipo de tóxicos para o exterior das células, também expelem medicamentos, fazendo com que estes não tenham o efeito desejado dentro delas. As bombas de efluxo são transportadores que se encontram nas membranas de todo o tipo de células. Existem dois grandes tipos de bombas de efluxo: as primári

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3

Otrebska-Machaj, Ewa. "The search for new inhibitors of bacterial efflux pumps among amine derivates of 5-Arylidenehydantoin." Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM5010.

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L’objet de ces recherches était de trouver de nouveaux EPIs du système d’efflux AcrAB-TolC dans les groupes de dérivés d’amine de la 5-arylidenehydantoine et de la 5-arylideneimidazolone. Dans la première étape de recherche, 32 nouveaux dérivés ont été obtenus après modification de la structure lead P2.Un screening théorique du risque toxique et la prédiction des propriétés médicamenteuses des composés ont été réalisés en utilisant le programme OSIRIS qui calcule différentes propriétés médicamenteuses pertinentes basées sur la structure planaire de la molécule.Dans l’étape suivante de la reche

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4

Filippin, Fernanda Branco. "Avaliação da atividade citotóxica e melanogênica do complexo de platina (II) com derivado de hidantoína em melanoma." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/9/9141/tde-15012014-151634/.

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Considerando o melanoma a forma mais agressivas de câncer de pele e mais resistente aos tratamentos convencionais, o presente estudo teve como objetivo avaliar a atividade de um novo complexo de platina (II) com derivado de hidantoína (CX42) em células de melanoma humano e murino. Foram utilizados também para comparação células da pele (fibroblastos, queratinócitos e melanócitos) e os compostos cisplatina (CIS) e complexo de hidantoína isolado (NN10). Ensaios de viabilidade, ciclo e morte celular foram realizados. Investigou-se também a atividade da enzima tirosinase, principal enzima que regu

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5

Huang, Jia-Yun, and 黃佳筠. "(I) Synthesis of Thio(seleno)hydantoin-fused tetrahydroisoquinolines and diketopiperazine-fused tetrahydroisoquinolines (II) One-pot Synthesis of Chiral 2-imino thia(selena)zole derivatives and 2-thio(seleno)xoimidazolin-4-ones." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/b2757e.

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碩士<br>國立交通大學<br>應用化學系碩博士班<br>107<br>The first part deals with the diastereoselective synthesis of thio(seleno)-hydantoin-fused tetrahydroisoquinolines and diketopiperazine-fused tetrahydro-isoquinolines via the molecular hybridization synthetic strategy. The second part describes the one-pot regioselective synthesis of chiral 2-iminothia(selena)zole derivatives and 2-thio(seleno)xoimidazolin-4-ones through multi-component reactions.

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Books on the topic "Derivatives of hydantoin"

1

The World Market for Hydantoin and Its Derivatives: A 2004 Global Trade Perspective. Icon Group International, Inc., 2005.

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2

Parker, Philip M. The 2007 Import and Export Market for Hydantoin and Its Derivatives in China. ICON Group International, Inc., 2006.

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3

Parker, Philip M. The World Market for Hydantoin and Its Derivatives: A 2007 Global Trade Perspective. ICON Group International, Inc., 2006.

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4

Parker, Philip M. The 2007 Import and Export Market for Hydantoin and Its Derivatives in United States. ICON Group International, Inc., 2006.

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Conference papers on the topic "Derivatives of hydantoin"

1

Smit, Biljana, Ivana Radojevic, Marijana Djukic, Ljiljana Comic, and Darko Asanin. "Antimicrobial Activity of Various Hydantoin Derivatives ." In 2nd International Electronic Conference on Medicinal Chemistry. MDPI, 2016. http://dx.doi.org/10.3390/ecmc-2-a032.

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2

Haq, Kautsar Ul, Septi Rosiana Dewi, Sherly Dwi Cicilianingrum, et al. "Synthesis of 5-benzylidene-hydantoin and 5-benzylidene-creatinine derivatives under mixed catalyst systems of urea-p-toluenesulfonic acid (Urea-PTSA) and guanidine hydrochloride-triethylamine (GnHCl-TEA)." In THE 14TH JOINT CONFERENCE ON CHEMISTRY 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0005378.

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