Relevant bibliographies by topics / Derivatives of pyrimidine

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Academic literature on the topic 'Derivatives of pyrimidine'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Derivatives of pyrimidine"

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Verma, Vishal, Chandra Prakash Joshi, Alka Agarwal, Sakshi Soni, and Udichi Kataria. "A Review on Pharmacological Aspects of Pyrimidine Derivatives." Journal of Drug Delivery and Therapeutics 10, no. 5 (2020): 358–61. http://dx.doi.org/10.22270/jddt.v10i5.4295.

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Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. One of the three diazines (six-membered heterocyclics with two nitrogen atoms in the ring), it has the nitrogens at positions 1 and 3 in the ring. Pyrimidines are typically synthesized by the “Principal Synthesis” involving cyclization of beta-dicarbonyl compounds with N-C-N compounds. Reaction of the former with amidines to give 2-substituted pyrimidines, with urea to give 2-pyrimidiones, and guanidines to give 2-aminopyrimidines are typical. Pyrimidines can be prepared via the biginelli reaction. Many other methods
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Hossain, M. I., and M. M. H. Bhuiyan. "Synthesis and Antimicrobial Activities of Some New Thieno and Furopyrimidine Derivatives." Journal of Scientific Research 1, no. 2 (2009): 317–25. http://dx.doi.org/10.3329/jsr.v1i2.2299.

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Fused pyrimidines, 8,9-dimethyl[1,2,4]triazolo[4,3-c]thieno[3,2-e]pyrimidine 5, 3,8,9-trimethyl[1,2,4]triazolo[4,3-c]thieno[3,2-e]pyrimidine 6, 4-benzylidinehydrazono-5,6 dimethylthieno[2,3-d]pyrimidine 7, 4-[4/-hydroxybenzylidine]hydrazono-5,6-dimethylthi-eno[2,3-d]pyrimidine 8, 4-[4/-tolylidin]hydrazono-5,6-dimethylthieno[2,3-d]pyrimidine 9, 4-[4/-nitrobenzylidine]hydrazono-5-ethyl-6-methylthieno[2,3-d]pyrimidine 10 and 4-[4/-chlorobenzylidine]hydrazono-5-ethyl-6-methylthieno[2,3-d]pyrimidine 11 are prepared in good yield by an initial treatment of 2-amino-4,5-dimethylthiophene-3-carbonitril
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Dabaeva, V. V., M. R. Baghdasaryan, I. M. Barkhudaryants, E. G. Paronikyan, and Sh Sh Dashyan. "Synthesis of new fused 3(4)-substituted 11-furylthieno[3,2-<i>d</i>]pyrimidine derivatives." Журнал общей химии 93, no. 9 (2023): 1351–57. http://dx.doi.org/10.31857/s0044460x23090056.

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A method was developed for the synthesis of new fused 3-alkyl-substituted derivatives of thieno[3,2- d ]pyrimidin-4(3 H )-ones based on 11-(2-furyl)-8,8-dimethyl-7,10-dihydro-8 H -pyrano[3′′,4′′:5′,6′]pyrido[3′,2′:4,5]-thieno[3,2- d ]pyrimidin-4(3 H )-one via nucleophilic substitution in the pyrimidine ring. A series of fused 4-amino-substituted 11-furylthieno[3,2- d ]pyrimidine derivatives was also synthesized from the corresponding 4-chloro derivative.
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Sirakanyan, Spinelli, Geronikaki, et al. "Synthesis, Antitumor Activity, and Docking Analysis of New Pyrido[3’,2’:4,5]furo(thieno)[3,2-d]pyrimidin-8-amines." Molecules 24, no. 21 (2019): 3952. http://dx.doi.org/10.3390/molecules24213952.

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Continuing our research in the field of new heterocyclic compounds, herein we report on the synthesis and antitumor activity of new amino derivatives of pyrido[3’,2’:4,5](furo)thieno[3,2-d]pyrimidines as well as of two new heterocyclic systems: furo[2–e]imidazo[1,2-c]pyrimidine and furo[2,3-e]pyrimido[1,2-c]pyrimidine. Thus, by refluxing the 8-chloro derivatives of pyrido[3’,2’:4,5]thieno(furo)[3,2-d]pyrimidines with various amines, the relevant pyrido[3’,2’:4,5]thieno(furo)[3,2-d]pyrimidin-8-amines were obtained. Further, the cyclization of some amines under the action of phosphorus oxychlori
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SABIU RABILU ABDULLAHI, ABUBAKAR MUHD SHAFI’I, SAPNA RAGHAV, and MA’ARUF ABDULMUMIN MUHAMMAD. "Pyrimidine derivatives: Recent discoveries and development towards its medicinal impact." GSC Advanced Research and Reviews 20, no. 1 (2024): 114–28. http://dx.doi.org/10.30574/gscarr.2024.20.1.0248.

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Pyrimidine derivatives' many biological functions and possible therapeutic uses have attracted a lot of research in the field of medicinal chemistry. Recent developments in the synthesis, biological assessment, and therapeutic uses of molecules based on pyrimidines are highlighted in this review. The significance of pyrimidine derivatives in treating a range of ailments, including cancer, infectious diseases, and metabolic disorders, is discussed, along with innovative synthesis approaches and important pharmacological findings. In order to give a thorough picture of the present status of pyri
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SABIU, RABILU ABDULLAHI, MUHD SHAFI'I ABUBAKAR, RAGHAV SAPNA, and ABDULMUMIN MUHAMMAD MA'ARUF. "Pyrimidine derivatives: Recent discoveries and development towards its medicinal impact." GSC Biological and Pharmaceutical Sciences 20, no. 1 (2024): 114–28. https://doi.org/10.5281/zenodo.13640628.

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Pyrimidine derivatives' many biological functions and possible therapeutic uses have attracted a lot of research in the field of medicinal chemistry. Recent developments in the synthesis, biological assessment, and therapeutic uses of molecules based on pyrimidines are highlighted in this review. The significance of pyrimidine derivatives in treating a range of ailments, including cancer, infectious diseases, and metabolic disorders, is discussed, along with innovative synthesis approaches and important pharmacological findings. In order to give a thorough picture of the present status of pyri
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Sarwade, Prakash Pralhad, K. M. Srinandhinidevi, Kiran Dangwal, et al. "Role of Pyrimidine Derivatives in the Treatment of Cancer." Journal for Research in Applied Sciences and Biotechnology 3, no. 5 (2024): 181–93. http://dx.doi.org/10.55544/jrasb.3.5.19.

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The study of the chemistry of pyrimidines is contributing to the expansion of research into the therapeutic applications of these compounds. In the field of medicinal chemistry, the sheer number of pyrimidine synthesis methods and reactions that are available opens up a world of possibilities. These investigations have been inspired by the fact that pyrimidines can be used as building blocks for a wide variety of compounds that have a physiological effect. The pyrimidine ring and its fused derivatives, which include pyrazolo[3,4-d]pyrimidine, pyrido[2,3-d]pyrimidine, quinazoline, and furo[2,3-
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Harnden, MR, and DT Hurst. "The Chemistry of Pyrimidinethiols. III. The Synthesis of Some Substituted Pyrimidinthiols and Some Thiazolo[5,4-D]pyrimidines." Australian Journal of Chemistry 43, no. 1 (1990): 55. http://dx.doi.org/10.1071/ch9900055.

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The preparation of a number of pyrimidinethiols and (substituted) thiopyrimidines has been carried out. The reaction of 5-acetylamino-2-aminopyrimidine-4,6-diol with phosphorus penta -sulfide in pyridine gave 5-amino-2-methylthiazolo[5,4-d]pyrimidine-7-thiol which was used to prepare several additional novel pyrimidine derivatives. Hydrolysis of the 4-carboxymethylthio derivative by using 5M hydrochloric acid gave 2,5-diamino-6-mercaptopyrimidin-4-ol hy -drochloride whilst hydrolysis of 2-methyl-7-methylthiothiazolo[5,4-d]pyrimidin-5-amine gave the corresponding 4-hydroxy derivative. Several 4
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Solomyannyi, Roman, Sergii Slivchuk, Donald Smee, et al. "In vitro Activity of the Novel Pyrimidines and Their Condensed Derivatives Against Poliovirus." Current Bioactive Compounds 15, no. 5 (2019): 582–91. http://dx.doi.org/10.2174/1573407214666180720120509.

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Background: Substituted pyrimidine derivatives (non-nucleoside) are found to be associated with various biological activities. The various substituted pyrimidines are also having significant in vitro activity against different DNA and RNA viruses. The present study focuses on the anti-PV activity of new pyrimidines and their condensed derivatives. Methods: A series of novel pyrimidines and their condensed derivatives were synthesized and their structures were confirmed by spectral data. Their antiviral activities against poliovirus type 3 (PV-3) were evaluated in vitro. In cell culture, morpho
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Agarkov, Artem S., Dilyara O. Mingazhetdinova, Anna A. Nefedova, et al. "Synthesis and Structure of 6-Acetyl-2-Arylhydrazone Derivatives of Thiazolo[3,2-a]Pyrimidine." Organics 4, no. 3 (2023): 438–46. http://dx.doi.org/10.3390/org4030031.

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Triazolo[4,3-a]pyrimidine is one of the promising structural fragments for the development of drugs, including anticancer drugs. This work is devoted to the synthesis of a number of new 2-arylhydrazone derivatives of thiazolo[3,2-a]pyrimidine, which are synthetic precursors for triazolo[4,3-a]pyrimidines. The crystal structure of 6-acetyl-7-methyl-5-phenyl-2-(2-phenylhydrazineylidene)-5H-thiazolo[3,2-a]pyrimidin-3(2H)-one was established by SCXRD. In the reduction reaction of the compound, the following system was used: vanadium(V) oxide, and sodium borohydride in ethanol at room temperature,
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Dissertations / Theses on the topic "Derivatives of pyrimidine"

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Hill, Matthew D. (Matthew Dennis). "Direct synthesis of pyridine and pyrimidine derivatives." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/43776.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2008.<br>Vita.<br>Includes bibliographical references.<br>I. Synthesis of Substituted Pyridine Derivatives via the Ruthenium-Catalyzed Cycloisomerization of 3-Azadienynes. The two-step conversion of various N-vinyl and N-aryl amides to the corresponding substituted pyridines and quinolines, respectively, is described. The process involves the direct conversion of amides, including sensitive N-vinyl amides, to the corresponding trimethylsilyl alkynyl imines followed by a ruthenium-catalyzed protodesilylation and cyclois
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Chan, Heng Ming. "Synthesis of pyrimidine C-nucleoside analogues and triphosphate derivatives." Thesis, Boston College, 2008. http://hdl.handle.net/2345/36.

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Five pyrimidine C-nucleosides were prepared via Heck-type coupling reactions. These derivatives are designed to mimic dC and dU (or T). The minor groove O2 carbonyl in each derivative is replaced by a hydrogen, a fluorine, or a methyl group. The hydrogen-substituted dC analogue was converted into a 2’,3’-dideoxynucleoside, which was converted into a 5’-triphosphate derivative. The other two dC analogues were transformed into 5’-triphosphate derivatives immediately after Heck coupling reactions. These analogues will allow an examination of the nature and role of minor groove interactions betwee
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Sullivan, Shannon M. "Synthesis of 2,4-disubstituted pyrimidine derivatives as potential 5-HT7 receptor antagonist." unrestricted, 2008. http://etd.gsu.edu/theses/available/etd-05052008-153400/.

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Thesis (M.S.)--Georgia State University, 2008.<br>Title from file title page. Lucjan Strekowski, committee chair; A.L. Baumstark, Gabor Patonay, Doyle Barrow , committee members. Electronic text (68 p. : ill.) : digital, PDF file. Description based on contents viewed June 23, 2008. Includes bibliographical references (p. 42-430.
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Sūdžius, Jurgis. "Synthesis And Properties Of Pyrimidine Derivatives – Potent Carbonic Anhydrase Inhibitors." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2011. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20110519_082332-05105.

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The aim of the work was design of pyrimidine derivatives – potent carbonic anhydrase (CA) inhibitors. Theoretical investigation of interaction of 4-[N-(pyrimidin-4-yl)]aminobenzenesulfonamides containing substituents at 2-, 5- and 6- positions of pyrimidine ring with an active site of hCAs suggested that these compounds can fit into an active site of the enzymes and should interact with them as typical hCA inhibitors. Synthesis of target compounds was carried out by substitution of chloro group at 4,6-dichloropyrimidines containing cyano-, formyl- or nitro groups at position 5 of the pyrimidin
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Taleli, Lebusetsa. "Radiosynthesis of various pyrimidine derivatives and determining their uptake into cells." Thesis, Cape Peninsula University of Technology, 2009. http://hdl.handle.net/20.500.11838/744.

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Thesis (MTech (Chemistry))--Cape Peninsula University of Technology, 2009<br>N3-substituted pyrimidine nucleoside derivatives containing either an iodovinyl moiety or an allyl group, i.e. [121]-N3-(3-iodoprop-2-en- l -yl)thymidine, (1~-711 and e21]-N3-(prop-2-enl- yl)-5-iodo-Z'-deoxyuridine, (1~_10, were synthesised and preliminarily evaluated by determining their uptake into CHO-Kl cells. Compound e~-711 was designed to be a delivery vector of 121: into the DNA of the cells, while (1~_10 was designed to serve as a control. Compound (1231]-711 was also intended to have a higher metabolic
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Weiss, Jason Thomas. "Development and application of bioorthogonal palladium-labile derivatives of cytotoxic pyrimidine analogues." Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/15957.

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Chemotherapy is widely used to treat various forms of cancer. However, some chemotherapeutic drugs, due to their antineoplastic properties, also act upon healthy cells which normally replicate rapidly causing a plethora of undesirable side effects. One rising and promising therapeutic strategy is the development of prodrugs. Prodrugs are derivatives of the pharmaceutically active drugs but require an enzymatic or biochemical transformation within a certain biological space in order for it to become activated and capable of exerting the desired pharmacological effect. As a novel prodrug approac
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Li, Jiyang [Verfasser]. "Investigation of Phthalazine, Quinazoline and Pyrimidine Derivatives as ABCG2 Inhibitors / Jiyang Li." Bonn : Universitäts- und Landesbibliothek Bonn, 2018. http://d-nb.info/1167857135/34.

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Howie, Colin. "The design, synthesis and testing of hydantoin derivatives as inhibitors of pyrimidine biosynthesis." Thesis, University of Glasgow, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.278514.

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Rango, Enrico. "PRECLINICAL CHARACTERIZATION OF SFK INHIBITORS, PYRAZOLO[3,4-d]PYRIMIDINE SCAFFOLD-BASED DERIVATIVES, FOR CANCER TREATMENT." Doctoral thesis, Università di Siena, 2021. http://hdl.handle.net/11365/1140389.

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The first part of this thesis essentially focuses on the preclinical characterization of Si306, a pyrazolo[3,4-d]pyrimidine derivative, identified as a very promising anticancer agent. This compound has shown a favorable in vitro and in vivo activity profile against neuroblastoma (NB) and glioblastoma (GBM) models by acting as a competitive inhibitor of c-Src tyrosine kinase. Nevertheless, the good antitumor activity of Si306 is associated with sub-optimal aqueous solubility, which might hinder its further development. In this context, drug delivery systems were developed to overcome the poor
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GIACCHELLO, ILARIA. "Synthesis of properly substituted pyridine and pyrimidine derivatives and their biological evaluation as potential antiviral agents." Doctoral thesis, Università degli studi di Genova, 2019. http://hdl.handle.net/11567/940944.

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Influenza A viruses (IAVs) belong to the Orthomixoviridae, a family of enveloped viruses with a single-stranded negative-sense and eight-segmented RNA genome. They are the most prevalent pathogens for both humans and animals, causing the so-called seasonal flu and widespread pandemics. A part from the use of vaccines, viral infections can be inhibited at several crucial steps by the use of antiviral agents. It is possible to have an antiviral effect both targeting important proteins for the virus life cycle and targeting host proteins that play crucial roles during influenza virus infection. R
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Books on the topic "Derivatives of pyrimidine"

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Omar, Abdirahman Hagi Hassan. Reactions of trihalomethyl derivatives of pyridines and pyrimidines with nucleophiles. University of Salford, 1986.

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1951-, Lusty James R., Wearden Peter, and Moreno Virtudes, eds. CRC handbook of nucleobase complexes: Transition metal complexes of naturally occuring nucleobases and their derivatives. CRC Press, 1990.

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Chemistry of Pyrimidine Derivatives. Nova Science Publishers, Incorporated, 2024.

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(Editor), H. U. Bergmeyer, J. Bermeyer (Editor), and M. Bral (Editor), eds. Methods of Enzymatic Analysis, 3.eE, Vol. 7, Metabolites 2: Tri- and Dicarboxylic Acids, Purines, Pyrimidines and Derivatives, Coenzymes, Inorganic Compounds. 3rd ed. John Wiley & Sons, 1985.

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Lusty, James R., and Peter Wearden. Handbook of Nucleobase Complexes: Transition Metal Complexes of the Naturally Occurring Nucleobases and Their Derivative. CRC Press, 1991.

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Book chapters on the topic "Derivatives of pyrimidine"

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Inaki, Yoshiaki, Minoo Jalili Moghaddam, and Kiichi Takemoto. "Pyrimidine Derivatives as Lithographic Materials." In ACS Symposium Series. American Chemical Society, 1989. http://dx.doi.org/10.1021/bk-1989-0412.ch018.

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Hitchings, George H., Gertrude B. Elion, and Samuel Singer. "Derivatives of Condensed Pyrimidine Systems as Antimetabolites." In Ciba Foundation Symposium - Chemistry and Biology of Pteridines. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470718919.ch22.

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Schoettle, Sarah L., and Richard I. Christopherson. "Inhibition of Murine Amido Phosphoribosyltransferase by Folate Derivatives." In Purine and Pyrimidine Metabolism in Man VIII. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4615-2584-4_34.

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Caravatti, G., J. Brüggen, E. Buchdunger, et al. "Pyrrolo[2,3-d]pyrimidine and Pyrazolo[3,4-d]pyrimidine Derivatives as Selective Inhibitors of the EGF Receptor Tyrosine Kinase." In Anticancer Agents. American Chemical Society, 2001. http://dx.doi.org/10.1021/bk-2001-0796.ch014.

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Bronson, Joanne J., Choung Un Kim, Ismail Ghazzouli, Michael J. M. Hitchcock, Earl R. Kern, and John C. Martin. "Synthesis and Antiviral Activity of Phosphonylmethoxyethyl Derivatives of Purine and Pyrimidine Bases." In ACS Symposium Series. American Chemical Society, 1989. http://dx.doi.org/10.1021/bk-1989-0401.ch005.

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Nimmo-Smith, R. H. "The Function of Folic Acid in the Biosynthesis of Purine and Pyrimidine Derivatives." In Ciba Foundation Symposium - Chemistry and Biology of Pteridines. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470718919.ch19.

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Gaikwad, Nikhil, and Y. V. Madhavi. "Design, Synthesis and Biological Evaluation of 3-Phenylisoxazolo[5,4-d]Pyrimidine Derivatives as Anticancer Agents." In Special Publications. Royal Society of Chemistry, 2019. http://dx.doi.org/10.1039/9781839160783-00085.

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Futami, Kitaro, and Sumitaka Arima. "Investigation of Thymidylate Synthase Induction in Colorectal Carcinoma Tissues After Administration of Anticancer Drug, Fluorinated Pyrimidine Fluoride Derivatives." In Recent Advances in Management of Digestive Cancers. Springer Japan, 1993. http://dx.doi.org/10.1007/978-4-431-68252-3_166.

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Vijaybhanu, P., D. R. Harish Kumar, L. Ramya, and C. H. S. Venkataramana. "Design, Synthesis, Characterisation and Antifungal Activity of Novel Pyrimidone Derivatives." In Special Publications. Royal Society of Chemistry, 2019. http://dx.doi.org/10.1039/9781839160783-00117.

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Meldrum, B. S., J. H. Swan, M. H. Millan, et al. "A Pyrimidine Derivative, BW 1003C87, Decreases Glutamate Release and Protects Against Ischemic Damage." In The Role of Neurotransmitters in Brain Injury. Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3452-5_3.

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Conference papers on the topic "Derivatives of pyrimidine"

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Stojković, Danijela, Sandra Jovičić Milić, Dušica Simijonović, Edina Avdović, Tamara Mladenović, and Zoran Marković. "In Vitro and in Silico Binding Studies of Chromeno-Pyrimidine Derivatives With Biological Important Protein-Part III." In 2024 IEEE 24th International Conference on Bioinformatics and Bioengineering (BIBE). IEEE, 2024. https://doi.org/10.1109/bibe63649.2024.10820495.

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Lukovits, I., T. Kosztolányi, E. Kálmán, and G. Pálinkás. "Corrosion Inhibitors: Correlation between Chemical Structure and Efficiency." In CORROSION 1999. NACE International, 1999. https://doi.org/10.5006/c1999-99242.

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Abstract Corrosion inhibition efficiencies of heterocyclic, aromatic or partially saturated aromatic compounds (pyrimidines, benzothiazole derivatives, amino-acids containing an aromatic part, pyridines and quinolines) were correlated with quantum chemical indices of the respective molecules. Inhibition efficiencies measured in acidic solutions containing 0.001 and 0.01 mol/L of the inhibitor, respectively, were collected. The quantum chemical calculations were done by using the simple Hückel method. Comparison of inhibition efficiencies and the differences between energies of the highest occu
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Simijonović, Dušica, Edina Avdović, Žiko Milanović, Dejan Milenković, and Zoran Marković. "Green synthesis of chromeno-pyrimidine derivatives – Part I." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.686s.

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Two different chromeno-pyrimidine derivatives were synthetized in the ionic liquid catalyzed reaction of barbituric acid and substituted salicylaldehydes. The product 5-(7-bromo-2,4-dioxo-1,3,4,5-tetrahydro-2H-chromeno[2,3-d]pyrimidin-5-yl)pyrimidine-2,4,6(1H,3H,5H)-tri-one (CP-1) was obtained in the reaction of barbiruric acid and 5-bromo-2-hydroxybenzaldehyde. The second new product 8,9-dihydroxy-2H-chromeno[2,3-d]pyrimidine-2,4(3H)-dione (CP-2) was yielded in the reaction between barbituric acid and 2,3,4-trihydroxybenzaldehyde. These products were isolated in moderate to good yield after 3
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Avdović, Edina, Dušica Simijonović, Žiko Milanović, Sandra Jovičić Milić, Sunčica Roca, and Dražen Vikić-Topić. "Chromeno-pyrimidine-type compounds (part II): in vitro evaluation of antioxidant potential." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.690a.

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The chromeno and pyrimidine classes compounds include a variety of hybrid molecules displaying diverse biological actions. Although they have been examined for many years, these compounds are still of interest due to their facile chemical transformations. The presence of chromeno and pyrimidine structural motifs in many drugs, prompted us to investigate the antioxidant features of compounds 5-(7-bromo-2,4-dioxo-1,3,4,5-tetrahydro-2H-chromeno[2,3-d]pyrimidin-5-yl) pyrimidine-2,4,6(1H,3H,5H)-tri-one (CP-1) and 8,9- ihydroxy-2H-chromeno[2,3-d]pyrimidine-2,4(3H)-dione (CP-2). In this paper, we inv
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Xavier, Augusto L., Daniel S. Alexandrino, Emerson P. S. Falcão, Rajendra M. Srivastava, and Janaina V. dos Anjos. "A green, microwave-mediated, multicomponent synthesis of pyrimidine and pyrimidinone derivatives." In 14th Brazilian Meeting on Organic Synthesis. Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0024-1.

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Tsygankova, V., I. Voloshchuk, Ya Andrusevich, S. Pilyo, and V. Brovarets. "Study of the growth-stimulating properties of pyrimidine derivatives on sugar sorghum (Sorghum saccharatum L.) variety Zubr." In international scientific-practical conference. MYKOLAYIV NATIONAL AGRARIAN UNIVERSITY, 2024. http://dx.doi.org/10.31521/978-617-7149-78-0-47.

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The growth-stimulating properties of synthetic pyrimidine derivatives on sugar sorghum (Sorghum saccharatum L.) variety Zubr grown for 2 weeks in laboratory conditions were studied. The morphometric indicators of sorghum plants treated with an aqueous 10-6 M solution of pyrimidine derivatives were compared with the indicators of sorghum plants treated with an aqueous 10-6 M solution of synthetic plant growth regulators Ivin, Methyur, Kamethur and phytohormone auxin IAA. Control sorghum plants were treated with distilled water. Conducted studies have shown that synthetic pyrimidine derivatives
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7

Sivapriya, S., S. Priyanka, D. Sivakumar, M. Gopalakrishnan, M. Seenivasan, and H. Manikandan. "Experimental and optimized studies of some pyrimidine derivatives." In INTERNATIONAL CONFERENCE ON RECENT TRENDS IN APPLIED MATHEMATICAL SCIENCES (ICRTAMS-2020). AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0063017.

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8

Engasheva, E. S., and D. D. Novikov. "THE EFFICACY OF THE COMBINATION DRUG AGAINST APHANIPTEROSIS IN CATS." In THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL. VNIIP – FSC VIEV, 2025. https://doi.org/10.31016/978-5-6053355-1-1.2025.26.100-104.

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Abstract:
The insecticidal efficacy and safety of a new combination drug in tablet formulation based on derivatives of spinosyns, pyrimidines and pyrazinoisoquinoline against aphanipterosis in cats was studied. The study was carried out on 16 animals with spontaneous infestation with fleas Ctenocephalides spp. which were divided into two groups: experimental and control groups of 8 animals each. The animals of the experimental group were given the drug individually, once, orally, on the root of the tongue immediately after feeding in the minimum dose per 1 kg of animal weight (by active ingredients): 50
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Amalina, Ilma, Ni Nyoman Tri Puspaningsih, and Hery Suwito. "In Silico analysis of pyrimidine derivatives as potential antibacterial agents." In PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON ADVANCED TECHNOLOGY AND MULTIDISCIPLINE (ICATAM) 2021: “Advanced Technology and Multidisciplinary Prospective Towards Bright Future” Faculty of Advanced Technology and Multidiscipline. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0121466.

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10

AL-Dawoody, Payman, Hala AL-Zahawi, and Nurhan Chelebi. "Preparation and characterization of some pyrimidine derivatives and study with CT DNA." In 2ND INTERNATIONAL CONFERENCE ON APPLIED RESEARCH AND ENGINEERING (ICARAE2022). AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0171353.

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