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Dissertations / Theses on the topic 'Derivatives of Salicylic Acid'

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Published: 5 June 2025

Last updated: 1 August 2025

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1

Montis, Riccardo. "A structural systematic study of three families of salicylic acid derivatives." Thesis, University of Southampton, 2011. https://eprints.soton.ac.uk/191349/.

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Crystal structure assembly is a subtle compromise between geometrical features, a natural tendency to minimize the free, empty, volume, linked to the involvement of classical van der Waals forces, and the ability of particular complementary functional groups to form additional cohesive directional interactions. Depending on the system considered, each of these factors can have a more pronounced influence in determining the crystal packing. In order to develop a successful strategy to design new solid forms by a crystal engineering approach a complete understanding of crystal structure is requi

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2

Langham, Jennifer. "Effects of aspirin and its derivatives in combination with electroporation for drug delivery in cultured cells." [Tampa, Fla.] : University of South Florida, 2004. http://purl.fcla.edu/fcla/etd/SFE0000614.

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3

Nordström, Fredrik. "Solid-liquid Phase Equilibria and Crystallization of Disubstituted Benzene Derivatives." Doctoral thesis, KTH, Teknisk strömningslära, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4742.

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The Ph.D. project compiled in this thesis has focused on the role of the solvent in solid-liquid phase equilibria and in nucleation kinetics. Six organic substances have been selected as model compounds, viz. ortho-, meta- and para-hydroxybenzoic acid, salicylamide, meta- and para-aminobenzoic acid. The different types of crystal phases of these compounds have been explored, and their respective solid-state properties have been determined experimentally. The solubility of these crystal phases has been determined in various solvents between 10 and 50 oC. The kinetics of nucleation has been inve

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4

Monte, Lucas de Oliveira. "Efeito antinociceptivo do salicilato de bornila em camundongos." Universidade Federal da Paraíba, 2014. http://tede.biblioteca.ufpb.br:8080/handle/tede/6805.

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Made available in DSpace on 2015-05-14T12:59:57Z (GMT). No. of bitstreams: 1 arquivototal.pdf: 1028566 bytes, checksum: 135624ca9af80cfe33db04d68975de22 (MD5) Previous issue date: 2014-02-07<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>The pain is a serious public health problem, affects the quality of life of their patients, he brings harm to society. The science continues to seek new more potent analgesic drugs and with fewer side effects. Bornyl salicylate (BS) is a salicylic acid derivative obtained by esterification of salicylic acid with the monoterpene (

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5

Macaulay, Keith Malcolm. "Salicylic acid biosynthesis in higher plants." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609202.

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6

Bi, Yong Mei. "Salicylic acid in plant defense responses." Thesis, University of Leicester, 1995. http://hdl.handle.net/2381/35437.

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The importance of salicylic acid (SA) in both local resistance to pathogens and the subsequent establishment of systemic acquired resistance has been investigated in tobacco. In order to assess the role of SA in the plant defense response, it was decided to try to stop the accumulation of SA by expression of an enzyme able to degrade it. A gene encoding salicylate hydroxylase (SH-L) was cloned from Pseudomonas putida and shown to be functional in E. coli. This gene was fused to various plant promoters which should allow temporal and spatial alteration of salicylate accumulation in pathogen-cha

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7

Fu, S. F. "Salicylic acid induced resistance to plant viruses." Thesis, University of Cambridge, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599252.

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Mitochondrial alternative oxidase (AOX) plays a role in protecting plant cells against reactive oxygen species. The SA-inducible RNA-directed RNA polymerase 1 (RDR1), contributes to viral RNA degradation via RNA interference. Previous data suggested that these enzymes comprise separately regulated, redundant elements in SA-induced resistance to viruses. To test this hypothesis, I constructed transgenic tobacco<i> (Nicotiana tabacum) </i>and <i>N. benthamiana </i>plants compromised simultaneously in AOX function and RDR1 activity. Transgenic tobacco and <i>N. benthamiana </i>plants were charact

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8

Jesus, Cláudia Marisa de. "Salicylic acid and drought tolerance improvement in Eucalyptus." Master's thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/13377.

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Mestrado em Biologia Aplicada<br>Covering approximately 20 million ha, Eucalyptus genus is the most widely planted hardwood trees all over the world. In the Mediterranean region, the positive performance of Eucalyptus plantations is conditioned by low water availability that strongly limits forest productivity and alters plant growth and development. Plant drought tolerance can be managed by adopting strategies such as exogenous application of hormones. Salicylic acid (SA) is a plant endogenous regulator of growth (PGR) that has been reported as a compound playing a key role in plants response

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9

Latham, Daniel Paul. "Controlled release of salicylic acid from silicone delivery systems." Thesis, Queen Mary, University of London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497788.

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10

Dodge, Kathryn. "Biodegradation of salicylic acid by natural and recombinant bacteria." Thesis, University of Liverpool, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272736.

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11

Naylor, Martin. "The effects of salicylic acid on RNA plant viruses." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624519.

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12

Li, Yuan. "Redox regulation of salicylic acid synthesis in plant immunity." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/19578.

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Salicylic acid (SA) is essential to the establishment of both local and systemic acquired resistance (SAR) against a wide range of phytopathogens. Isochorismate synthase 1 (ICS1) is the key enzyme involved in the synthesis of SA and it is transcriptionally activated by the regulatory proteins SAR deficient 1 (SARD1) and Calmodulin binding protein 60g (CBP60g). It has been demonstrated previously that the loss-of-function mutant, S-nitrosogluthione reductase 1-3 (gsnor1-3), increased cellular levels of S-nitrosylation. Significantly, accumulation of both free SA and its storage form SA-glucosid

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13

Baxter, Gwendoline Joan. "An investigation of the origins of salicylic acid in man." Thesis, University of Strathclyde, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.410218.

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14

Howladar, Saad Mohammed. "Effects of salicylic acid on salinity tolerance of wheat (Triticum aestivum)." Thesis, University of Reading, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.553172.

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Four glasshouse experiments examined salinity stress and tolerance in wheat. The first experiment examined the responses of three wheat cultivars from Saudi Arabia (Local wheat, West bread and Yecora Rojo) and two UK wheat cultivars (Paragon and Belvoir) to different levels of salinity (Tap water, 25, 50, 100, 150 and 200 mM NaCI). In the second experiment, Yecora Rojo and Paragon were selected to test whether improved wheat tolerance to salinity could be obtained by applying exogenous Salicylic acid (0, 0.5, 1 and 2 mM SA) via priming seeds for 6 hours. The third experiment further tested the

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15

Wong, Chui Eng. "Signalling in Salicylic acid-induced resistance to viruses in Arabidopsis thaliana." Thesis, University of Cambridge, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.620396.

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16

Chivasa, Stephen. "The mechanism of salicylic acid-induced resistance to tobacco mosaic virus." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624178.

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17

Felipe-Blanco, Diego. "Salicylic Acid-Catalyzed Radical Arylations from In-situ Formed Arenediazonium Salts." Doctoral thesis, Universidad de Alicante, 2020. http://hdl.handle.net/10045/112757.

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In this thesis, it has been studied the deamination of aromatic amines, through in situ formed diazonium salts as reaction intermediates, catalyzed by salicylic acid, a nontoxic, eco-friendly and economic catalyst. In the early part of the thesis (Chapter I) it has studied the deamination process using THF as solvent as hydrogen donor and anilines as radical source, to carry the hydrodeamination reaction, as well as the process in its deuterodeamination manner using deuterated solvent. Following with this study in Chapter II and Chapter III, it has been studied the addition of the aromatic rad

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18

Fai, Leonard Yenwong. "Subcellular Localization of Tobacco Salicylic Acid Binding Protein 2 in Plants." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etd/1274.

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Salicylic Acid Binding Protein 2 (SABP2) is a 29kDa protein present in extremely low amounts in tobacco leaves. SABP2 processes the mobile defense signal, methyl salicylic acid generated in plants resisting microbial infection. The precise localization of SABP2 in plants is not known. SABP2 has not been shown to have any targeting signal peptides. This study was designed to determine localization of SABP2 in tobacco plants. Biochemical and immunological studies using antibodies against SABP2 suggest that it is localized to the chloroplast, associating with chloroplast envelope membranes. Chlor

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19

Peters, Steven Carlton. "Crosslinked amino acid derivatives." Title page, table of contents and abstract only, 1991. http://web4.library.adelaide.edu.au/theses/09PH/09php4831.pdf.

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20

Alharthi, Reem. "A Possible Role for Salicylic Acid-induced Genes in Fusarium Graminearum Infection." Thesis, Université d'Ottawa / University of Ottawa, 2015. http://hdl.handle.net/10393/32401.

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The ability of Fusarium graminearum to metabolize the plant hormone salicylic acid (SA) and use it as a carbon source was investigated in previous studies in our laboratory. The expression of some F. graminearum genes was upregulated in presence of SA. However, the role of those induced genes in SA degradation was not investigated. This study aimed at characterizing six candidate genes predicted to encode enzymes with ability to catalyze one of the first two-enzymatic steps in SA degradation by F. graminearum. Those genes are FGSG_09063, FGSG03657, FGSG_09061, FGSG_03667, FGSG08358 and FGSG_08

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21

陸兆輝 and Shiu-fai Luk. "Analysis of ascorbic, sorbic and salicylic acid in food and related products." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1985. http://hub.hku.hk/bib/B31207017.

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22

Nair, Aswin [Verfasser]. "Salicylic Acid (SA)-independent processes in Systemic Acquired Resistance (SAR) / Aswin Nair." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2021. http://d-nb.info/1230138110/34.

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23

Luk, Shiu-fai. "Analysis of ascorbic, sorbic and salicylic acid in food and related products /." [Hong Kong : University of Hong Kong], 1985. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12263771.

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24

O'Dell, Jacob Webb. "An analysis of dendritic cooperativity in protein hydrolysis." Thesis, Montana State University, 2005. http://etd.lib.montana.edu/etd/2005/odell/ODellJ0805.pdf.

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25

McCue, Alan J. "Heterogenisation of manganese salen complexes for epoxidation." Thesis, University of Aberdeen, 2012. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=185907.

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Silica functionalised with PAMAM dendrimer chains has been investigated as a support for anchoring chiral salen complexes in both an axial and covalent fashion. It was found that using a high dendrimer chain density resulted in very low enantioselectivity in the epoxidation of styrene, 1-methyl-1-cyclohexene and α-methylstyrene. Through a thorough series of tests the poor performance was attributed to both interactions with the surface and with neighbouring dendrimer chains. It was found that the system could be improved by decreasing the dendrimer chain density and pacifying the surface by ca

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26

Tadepalli, Adilakshmi. "Studies on the role of salicylic acid in iron metabolism of Mycobacterium smegmatis." Thesis, University of Hull, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.310316.

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27

Yuh, Joannes Petrus. "Effect of Pesticides on Salicylic Acid Binding Protein 2 (SABP2) and Plant Defense." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etd/2259.

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Tobacco SABP2 has been shown to display high affinity for salicylic acid (SA) and methylsalicylate (MeSA) and plays an important role in SAR signal development. Using biochemical approach, SABP2 has been shown to demonstrate strong esterase activity in converting MeSA to SA. Recent study shows that tetra fluoroacetophenone, a synthetic analog of SA, competitively inhibits SABP2 esterase activity as well as suppresses SAR signal development in tobacco mosaic virus (TMV)-infected tobacco plants. Not much has been studied on the effect of pesticides on plant defenses. Because both AChE and SABP2

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28

Box, Julian M. "Towards fluorinated derivatives of shikimic acid." Thesis, University of Reading, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286003.

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29

Van, Kralingen Leon. "Controlled polymerization of amino acid derivatives." Thesis, Link to the Internet, 2008. https://etd.sun.ac.za/jspui/handle/10019/919.

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30

Kociuba, Katherine. "Radical functionalisation of amino acid derivatives /." Title page, table of contents and abstract only, 1996. http://web4.library.adelaide.edu.au/theses/09PH/09phk76.pdf.

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31

Tan, Eng Wui. "Regioselective modification of amino acid derivatives /." Title page, contents and abstract only, 1990. http://web4.library.adelaide.edu.au/theses/09PH/09pht1612.pdf.

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32

Darby, Judith. "Systemic acquired resistance to Phytophthora infestans in potatoes and tomatoes." Thesis, University of Hull, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321051.

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33

Light, Fritz. "ALOE STRIATA PLANT DEFENSE COMPOUNDS PRODUCED IN RESPONSE TO JASMONIC ACID, SALICYLIC ACID, AND ERIOPHYID MITE SALIVARY EXTRACT ELICITOR COMPOUNDS." DigitalCommons@CalPoly, 2012. https://digitalcommons.calpoly.edu/theses/836.

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Aloe mites are herbivores of the genus Aloe (ALOACEAE) and are associated with hyperplastic growth in various aloe species, but the biochemistry of this interaction is poorly understood. In an effort to characterize plant defense responses to herbivory in the genus Aloe, a salivary extract was isolated from aloe mites (Aceria aloinis Keifer) and its bioactivity was tested using a hypocotyl elongation assay. Subsequently, Aloe striata plants were treated with jasmonic acid (JA), salicylic acid (SA), and the mite salivary extract. Using water and methanol, compounds of different polarity were ex

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34

Portell, Bueso Anna. "Crystal Engineering Studies of Squaric Acid Derivatives." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/285325.

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This thesis is a multidisciplinary study of the solid state of squaric acid derivatives which combines approaches from areas such as crystal engineering, supramolecular chemistry and crystallography. The structural preferences in the solid state of this family of compounds has been analyzed, new crystalline materials derived from squaric acid have been designed in order to study new supramolecular synthons and relevant chemical phenomena such as template effect, preorganization, cooperativity and electrostatic compression have been explored. In summary, 47 polymorphs, solvates, cocrystals

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35

Goubet, D. C. M. "Asymmetric synthesis of α-amino acid derivatives". Thesis, Swansea University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637081.

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A general background to α-amino acids is discussed in the first chapter. After a brief account on classification, properties and applications of these compounds, asymmetric processes leading to optically enriched residues are reviewed in detail. The second chapter describes the envisaged stereoselective approach towards these substrates involving Michael-type addition onto a chiral didehydroalanine derivative. Syntheses of α,β-unsaturated amino acids are reviewed after a brief section on Michael-type reactions. The preparation of a chiral didehydroamino acid residue has been investigated using

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36

Hay, M. P. "Atom transfer reactions of amino acid derivatives." Thesis, University of Canterbury. Chemistry, 1987. http://hdl.handle.net/10092/7974.

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Investigations of atom transfer reactions of amino acid derivatives are described in this thesis. Reaction of N-benzoylvaline methyl ester (29a) with sulphuryl chloride gave the β-chlorovaline derivative (30a) and lesser amounts of diastereoisomers of the r-chlorovaline derivative (31a). Studies of reactions of the valine derivatives (29a-c) with sulphuryl chloride, and of the photolyses of the corresponding N-chlorovaline derivatives (39a-c) have shown that the reaction of (29a) with sulphuryl chloride and the photolysis of (39a) involve regioselective intermolecular transfer of the respectiv

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37

Sanganee, Mahesh Jayantilal. "Synthesis of novel-functionalized phosphinic acid derivatives." Thesis, London Metropolitan University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391909.

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38

Peron, Guillaume Luc Nicolas. "Lewis acid mediated cyclisation of methylenecyclopropane derivatives." Thesis, University of Southampton, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326304.

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39

Sun, Jing. "Synthesis and Application of Boronic Acid Derivatives." Thesis, Virginia Tech, 2010. http://hdl.handle.net/10919/77006.

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Boronic acids are attractive synthetic intermediates and have been shown to be effective as inhibitors of various enzymes. In this project, the overarching goal is the selective inhibition of a protease present in the mitochondria known as human ClpXP. To study the potential selective inhibition of Human ClpXP using N-terminal peptidic boronic acid, we have designed a synthetic scheme that includes?-borylation of °,?-unsaturated carbonyl compounds using Cu(I) as catalyst, °-alkylation, saponification/hydrogenation, amidation, and oxidative removal of pinacolyl group with sodium periodate. A s

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40

Volckman, Janis F. "The synthesis of fungicidal aminophosphonic acid derivatives." Thesis, London Metropolitan University, 1988. http://repository.londonmet.ac.uk/3425/.

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A number of 1-aminoalkanephosphonic acid derivatives incorporating physiologically Iabile groupings (ester, amide e.g. peptide, carbamate and tosyl) were prepared as a development from earlier studies in which certain phosphonic acid derivatives were shown to have previously unrecognised activity as fungicides. Such derivatisation might aid the translocation of the active phosphonic acid to the site of action. Compounds were screened for in vivo fungicidal activity against Drechslera teres. Drechslera graminae. Drechslera avenae. Prythium ultlmum. Rhizoctonia solani. Fusarium culmorum. Pyricul

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41

Feuillet, Frederic. "Stereoselective synthesis of (E)-trisubstituted acid derivatives." Thesis, University of Bath, 2004. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.397111.

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42

Lee, Michael Ho Kei. "Hydrogen peroxide assisted heterogeneous photocatalytic oxidation of salicylic acid with novel oscillatory flow photocatalytic reactor /." View abstract or full-text, 2005. http://library.ust.hk/cgi/db/thesis.pl?EVNG%202005%20LEE.

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43

Chapagai, Danda P. "Biochemical Characterization of SBIP-470 and its role in SA-mediated Signaling in Plants." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etd/2428.

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Salicylic acid binding protein 2 (SABP2) is known to play a key role in Salicylic acid mediated defense pathway. SBIP-470 is SABP2 interacting protein that might be putatively involved in transfer of lipids. SBIP-470 was cloned without the signal peptide and expressed in E. coli. In vitro lipid binding assay using recombinant SBIP-470 failed to detect lipid binding. In vitro lipid transfer assay showed recombinant SBIP-470 does not transfer phospholipid. Study has shown that SBIP-470 is highly inducible upon infection with viral as well as bacterial pathogens. Induction of SBIP-470 expression

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44

Rotich, Moses Kipngeno. "Stability studies on some substituted aminobenzoic acids." Thesis, Rhodes University, 2003. http://hdl.handle.net/10962/d1005012.

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he thermal behaviour in the solid state of various substituted aminobenzoic acids (3-aminobenzoic acid (3-ABA), 4-aminobenzoic acid (4-ABA), 3-aminosalicylic acid (3-ASA), 4-aminosalicylic acid (4-ASA), and 5-aminosalicylic acid (5-ASA), as well as the "parent" benzoic acid (BA) and salicylic acid (SA) as reference substances, and possible decomposition products: 2-aminophenol (2-AP), 3-aminophenol (3-AP) and 4-aminophenol (4-AP), has been examined. The various sets of isomers studied showed considerable and interesting differences. Most sublimed well before melting, generally with an increasi

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45

Meakem, Victoria. "Induced defenses in apple fruits: linking fruit chemistry, quality, and plant-insect-microbe interactions." Thesis, Virginia Tech, 2020. http://hdl.handle.net/10919/99100.

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Plants synthesize a diverse array of phytochemicals in response to interactions with herbivores, pathogens, and commensal microbes. These phytochemicals may simultaneously enhance crop defense and quality, representing a potential pest management strategy. However, plant chemical responses to different types and levels of biotic interactions remain unclear, particularly in fruit tissues, and the feasibility of inducing these defenses through elicitor application in field environments also requires further examination. Thus, apples were used to 1) examine the impact of distinct communities of b

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46

Jacobs, Sarita. "Formulation, in vitro release and transdermal diffusion of salicylic acid and topical niacinamide / by Sarita Jacobs." Thesis, North-West University, 2009. http://hdl.handle.net/10394/3986.

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Acne affects as many as 80% of young adults and adolescents all over the world. This detrimental condition can be classified into four stages: (a) open comedo (blackhead), (b) closed comedo (whitehead), (c) papule and (d) pustule (Russell, 2000:357-366). There are various factors that can lead to acne outbreaks which include: (a) hormone level changes during the menstrual cycle in women, (b) certain drugs (i.e. lithium), (c) certain cosmetics and (d) environmental conditions such as humidity (University of Maryland, 2009:1). The skin performs a variety of functions which include the two major

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47

Eddo, Alexander. "Characterization of the Pathway Leading to the Synthesis of Salicylic Acid in Plants Resisting Pathogen Infection." Digital Commons @ East Tennessee State University, 2008. https://dc.etsu.edu/etd/1958.

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Salicylic acid is a plant hormone that accumulates with plant-pathogen interaction. This accumulation corresponds to the plant being resistant to infection and without it the plant is susceptible. In this study, primers of genes involved in the normal synthesis of SA were used in RT-PCR to compare gene expression levels in susceptible and resistant plants challenged with tobacco mosaic virus. Because SA synthesis shares chorismate as a common substrate with the synthesis of aromatic amino acids, HPLC was used to determine whether the increase in SA could be attributed to a decrease in amino ac

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48

Schult, Tove. "Properties of acid sulfite cellulose for cellulose derivatives." Doctoral thesis, Norwegian University of Science and Technology, Department of Chemical Engineering, 2000. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-1508.

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49

Motto, John M. "Ã,ß-unsaturated sulfoxides and sulfinic acid derivatives." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ58363.pdf.

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50

Rhoden, Stephen. "SYNTHESIS OF NOVEL AZIRIDINE DERIVATIVES OF PODOCARPIC ACID." Master's thesis, University of Central Florida, 2007. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3569.

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Podocarpic acid (a diterpenoid resin acid extracted from the Podocarpacea specie of plants) has shown cytotoxicity against carcinoma of the nasopharynx. Since this discovery has been made, research has been performed in order to alter the structure of the resin acid so as to increase the anticancer activity. The carboxylic acid and phenol functional groups, which are present in podocarpic acid, make it possible to synthesize new derivatives selectively at the C-15, C-13, and C-7 positions as well as by substitution of the phenol hydroxyl group. Thus numerous derivatives can be prepared, in hig

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