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1

Sabah, Alharazy. "The dermatologic manifestations of COVID-19: a mini-review." Annals of Proteomics and Bioinformatics 5, no. 1 (2021): 042–48. http://dx.doi.org/10.29328/journal.apb.1001015.

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in Wuhan, China, and caused coronavirus disease-19 (COVID-19), which is still a global pandemic. Dermatologic manifestations have increasingly been identified as significant extrapulmonary manifestations of COVID-19. The dermatologic manifestations associated with COVID-19 infection reported to date include maculopapular rash, vesicular lesions, urticaria-like lesions, and chilblain-like lesions. Knowledge of dermatologic manifestations of COVID-19 may be essential for early diagnosis and a better prognosis in COVID-1
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Fernández-Lázaro, Diego, and Manuel Garrosa. "Identification, Mechanism, and Treatment of Skin Lesions in COVID-19: A Review." Viruses 13, no. 10 (2021): 1916. http://dx.doi.org/10.3390/v13101916.

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Coronavirus disease 2019 (COVID-19) is a multisystem disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), that primarily causes respiratory symptoms. However, an increasing number of cutaneous manifestations associated with this disease have been reported. The aim of this study is to analyze the scientific literature on cutaneous manifestations associated with SARS-CoV-2 by means of a narrative literature review until June 2021. The search was conducted in the following electronic databases: Medline (PubMed), SciELO, and Cochrane Library Plus. The most common cutaneo
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Martora, Fabrizio, Teresa Battista, Gabriella Fabbrocini, and Matteo Megna. "Concomitant Severe Psoriasis and Bullous Pemphigoid Induced by COVID-19." Tropical Medicine and Infectious Disease 8, no. 2 (2023): 107. http://dx.doi.org/10.3390/tropicalmed8020107.

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Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first isolated in Wuhan, China, is currently a pandemic. At the beginning of the pandemic, pulmonary issues were the most discussed and studied. However, now 3 years later, the role of the dermatologist has become increasingly central. Often the diversity in the presentation of these manifestations has made it difficult for the dermatologist to recognize them. In addition to the common symptoms involving fever, cough, dyspnea, and hypogeusia/hyposmia that have been widely discussed in t
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Kosovali, Behiye Deniz, Asiye Yavuz, Fatma Irem Yesiler, and Mustafa Kemal Bayar. "Melkersson-Rosenthal Syndrome: A Rare Cause of Recurrent Facial Nerve Palsy and Acute Respiratory Distress Syndrome." Case Reports in Neurological Medicine 2018 (June 10, 2018): 1–3. http://dx.doi.org/10.1155/2018/1373581.

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Melkersson-Rosenthal Syndrome (MRS) is a rare disease characterized by persistent or recurrent orofacial oedema, relapsing peripheral facial paralysis, and furrowed tongue. Pathologically, granulomatosis is responsible for oedema of face, labia, oral cavity, and facial nerve. We present a patient with MRS admitted to our hospital with acute respiratory distress syndrome (ARDS). 45-year-old woman was admitted to an emergency department with dyspnea and swelling on her hands and face. She was intubated because of ARDS and accepted to intensive care unit (ICU). After weaning from ventilatory supp
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Sehgal, Vineet, Lucky Bhalla, Priyanshu Bansal, and Shaifali Arora. "A rare case of multisystem inflammatory syndrome in adults-a diagnostic dilemma." International Journal of Advances in Medicine 9, no. 3 (2022): 337. http://dx.doi.org/10.18203/2349-3933.ijam20220382.

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Multisystem inflammatory syndrome (MIS) is a rare and severe post-infectious inflammatory disorder involving multiple systems (cardiovascular, gastrointestinal, dermatologic, nervous system, and haematological) without significant respiratory involvement. It is predominantly seen in children but sometimes in adults, usually after 3-6 weeks of COVID-19 infection or vaccination. It is postulated to be due to immune dysregulation. This case report adds to the limited literature available on post COVID MIS in adults, emphasizing how to reach the diagnosis after ruling out other differentials. Time
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Alviariza, Annisa, and Luh M. Budiani. "Dermatologic manifestation of COVID-19: a systematic review." International Journal of Research in Dermatology 7, no. 4 (2021): 565. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20212554.

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<p class="abstract">Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections, causing disease known as COVID-19, has been associated with a myriad of symptoms, including dermatological ones. Despite there has been a consensus on pulmonary and systemic signs and symptoms of COVID-19, the same cannot be said of dermatological ones. We write in attempt to find a common theme of dermatological manifestations of COVID-19. We conducted literature searches from Medline databases as well as Google Scholar using keywords “cutaneous manifestations of COVID-19” and “dermatologic mani
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Giaccone, Giuseppe, Mauro Risio, Gianmaria Bonardi, and Alessandro Calciati. "Stevens-Johnson Syndrome and Fatal Pulmonary Toxicity to Combination Chemotherapy Containing Bleomycin: A Case Report." Tumori Journal 72, no. 3 (1986): 331–33. http://dx.doi.org/10.1177/030089168607200316.

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Bleomycin is a commonly used anticancer agent; in particular, it is an important component of multidrug regimens for germ cell tumors. The limiting toxicity of bleomycin is represented by pulmonary interstitial fibrosis; mucocutaneous side effects are common, but usually harmless. We describe a case of a young girl who developed Stevens-Johnson syndrome following the administration of bleomycin in a three-drug regimen containing vinblastine and cisplatin, for an ovarian immature teratoma. The severe dermatologic toxicity was kept under control, but a rapidly evolving respiratory insufficiency
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Pendlebury, Gehan A., Peter Oro, William Haynes, Drew Merideth, Samantha Bartling, and Michelle A. Bongiorno. "The Impact of COVID-19 Pandemic on Dermatological Conditions: A Novel, Comprehensive Review." Dermatopathology 9, no. 3 (2022): 212–43. http://dx.doi.org/10.3390/dermatopathology9030027.

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Background: The earliest cases of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, in December 2019. Since the declaration as a pandemic on 11 March 2020, further dermatological conditions continue to be documented. We herein present a novel literature review of dermatological manifestations associated with the Coronavirus Disease 2019 (COVID-19) pandemic. To date, this literature review is the first broad-spectrum examination that analyzes a range of dermatological manifestations related to the COVID-19 pandemic: infection, vaccinations, personal protectiv
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9

Khader, Fathima Juhaina M. Abdul, M. Arhoul Rennies, R. S. Atchayavarshini, B. Deepasree, and G. Georglin Heavenlia. "Overlapping Stevens-Johnson Syndrome and Staphylococcal Scalded Skin Syndrome in a Three-Year-Old Child: A Rare Pediatric Dermatologic Emergency." International Journal of Medical and Pharmaceutical Case Reports 18, no. 3 (2025): 63–67. https://doi.org/10.9734/ijmpcr/2025/v18i3438.

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Aims: To report a rare pediatric case presenting with overlapping Stevens-Johnson Syndrome and Staphylococcal Scalded Skin Syndrome complicated by impetigo in a three -year-old child, highlighting diagnostic and therapeutic challenges. Presentation of Case: A three-year-old female child presented to the emergency department with fever, perioral vesicles, crusting, and perioral pain. The symptoms began after an upper respiratory tract infection and treatment with amoxicillin. Over a period of four days, the child developed worsening vesiculobullous lesions with perioral crusting and mucosal inv
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10

Hussain, Hussain, Michael J. Paidas, Ramamoorthy Rajalakshmi, et al. "Dermatologic Changes in Experimental Model of Long COVID." Microorganisms 12, no. 2 (2024): 272. http://dx.doi.org/10.3390/microorganisms12020272.

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The coronavirus disease-19 (COVID-19) pandemic, declared in early 2020, has left an indelible mark on global health, with over 7.0 million deaths and persistent challenges. While the pharmaceutical industry raced to develop vaccines, the emergence of mutant severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) strains continues to pose a significant threat. Beyond the immediate concerns, the long-term health repercussions of COVID-19 survivors are garnering attention, particularly due to documented cases of cardiovascular issues, liver dysfunction, pulmonary complications, kidney impair
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Alshafei, Atef, Mahmoud Ahmed, Fadhil Hussein, Mustafa Hassan, and Amira Mohamed. "A case of neonatal lupus erythematosus with multiorgan involvement and complete heart block." Journal of Pediatrics & Neonatal Care 9, no. 4 (2019): 106–9. http://dx.doi.org/10.15406/jpnc.2019.09.00388.

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Neonatal lupus erythematosus (NLE) is a rare autoimmune- mediated spectrum of disorders occurring in 1/20,000 live births and causing fetal tissue damage due to trans placental passage of anti-Sjögren’s-syndrome-related antigens A and B (anti Ro/SSA and anti La/SSB immunoglobulin G). Approximately 60% of the mothers are asymptomatic on diagnosis of NLE, while the remaining may have SLE, Sjögren syndrome, or other autoimmune disorders. Clinical presentation of NLE varies from dermatologic, cardiac, hepatic, splenic, hematologic, or neurogenic abnormalities. All except cardiac manifestations are
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Montelli, Terezinha C. B., Angela M. V. C. Soares, Maria R. Parise-Fortes, Maria T. Rezkallah-Iwasso, Niura M. R. Padula, and Maria Terezinha S. Peraçoli. "Alterations of cell-mediated immune response in children with febrile seizures." Arquivos de Neuro-Psiquiatria 55, no. 2 (1997): 193–98. http://dx.doi.org/10.1590/s0004-282x1997000200005.

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The aim of the present investigation was to study the distribution of T-cell subsets in peripheral blood defined by monoclonal antibodies and by the lymphocyte proliferative response to phytohemagglutinin (PH A) in 30 children with febrile seizures and in 14 age-matched control subjects. Frequent respiratory, urinary and dermatologic infections were observed in 22 patients. The immunologic parameters showed that 64% of the patients presented an increased number of CD8+ cells and a low helper/suppressor ratio was observed in 60% of the patients. In addition, the proliferative response of lympho
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Rivers, Jason K., John P. Arlette, Joel DeKoven, et al. "Skin care and hygiene among healthcare professionals during and after the SARS-CoV-2 pandemic." SAGE Open Medicine 9 (January 2021): 205031212110627. http://dx.doi.org/10.1177/20503121211062795.

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The severe acute respiratory syndrome coronavirus 2 pandemic has necessitated enhanced protection against viral transmission among healthcare professionals, particularly relating to handwashing and personal protective equipment. Some of these requirements may persist for years to come. They bring associated concerns around skin hygiene and general care, with damage to the face and hands now a well-documented consequence among healthcare professionals. This review assesses optimal skin care during the severe acute respiratory syndrome coronavirus 2 pandemic and in the “new normal” that will fol
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14

Kamra, Nidhi, and Ankita Tuknayat. "Apert syndrome: A dermatologist’s perspective." CosmoDerma 1 (December 16, 2021): 66. http://dx.doi.org/10.25259/csdm_64_2021.

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Apert syndrome is a Type 1 acrocephalosyndactyly syndrome presenting predominantly with craniofacial malformations and syndactyly. It can present with a multitude of clinical features involving any system of the body. A literature search of the PubMed electronic database was performed using the keywords “Apert syndrome” and “dermatology” in the title. The relevant references of the included articles were traced and included. A total of 27 articles appeared, the abstracts of which were screened and reviewed by both the authors independently for inclusion. After carefully analyzing all papers ca
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15

Beaupre II, Randall, Cody Petrie, and Alexander Toledo. "Mixed Purpuric and Maculopapular Lesions in a Patient with COVID-19: A Case Report." Clinical Practice and Cases in Emergency Medicine 4, no. 3 (2020): 349–51. http://dx.doi.org/10.5811/cpcem.2020.6.48617.

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Introduction: The coronavirus disease of 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 is a global pandemic that expresses itself with a wide variety of presenting symptoms in patients. There is a paucity of literature describing the dermatologic manifestations of the virus, particularly in the United States. Case Report: Here we present a case of COVID-19 that manifested with a purpuric rash on the lower extremities and a maculopapular eruption on the abdomen in a patient in acute diabetic ketoacidosis and normal platelet count. Discussion: The reported p
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Bjelica, Milena, Gordana Vilotijevic-Dautovic, Andrea Djuretic, and Slobodan Spasojevic. "A multisystem inflammatory syndrome in children associated with COVID-19 in a 11-years-old girl." Srpski arhiv za celokupno lekarstvo, no. 00 (2021): 78. http://dx.doi.org/10.2298/sarh210510078b.

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Introduction. Multisystem inflammatory syndrome in children (MIS-C) is a post-viral, life-threatening, inflammatory state with multisystem involvement that typically manifests 3-4 weeks after SARS-CoV-2 infection. In this article, we present the first case of MIS-C in the Institute for Child and Youth Health Care of Vojvodina at the beginning of the COVID-19 pandemic. Case outline. A previously 11-years-old healthy girl got sick two days before admission to the hospital with a fever, headache, vomiting, abdominal pain, and fatigue. She was tested positive for COVID-19 by nasopharyngeal swab PC
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Yoo, Su Woong, Gyungseok Oh, Jin Chul Ahn, and Euiheon Chung. "Non-Oncologic Applications of Nanomedicine-Based Phototherapy." Biomedicines 9, no. 2 (2021): 113. http://dx.doi.org/10.3390/biomedicines9020113.

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Phototherapy is widely applied to various human diseases. Nanomedicine-based phototherapy can be classified into photodynamic therapy (PDT) and photothermal therapy (PTT). Activated photosensitizer kills the target cells by generating radicals or reactive oxygen species in PDT while generating heat in PTT. Both PDT and PTT have been employed for treating various diseases, from preclinical to randomized controlled clinical trials. However, there are still hurdles to overcome before entering clinical practice. This review provides an overview of nanomedicine-based phototherapy, especially in non
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Stefanou, Maria-Ioanna, Lina Palaiodimou, Eleni Bakola, et al. "Neurological manifestations of long-COVID syndrome: a narrative review." Therapeutic Advances in Chronic Disease 13 (January 2022): 204062232210768. http://dx.doi.org/10.1177/20406223221076890.

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Accumulating evidence points toward a very high prevalence of prolonged neurological symptoms among coronavirus disease 2019 (COVID-19) survivors. To date, there are no solidified criteria for ‘long-COVID’ diagnosis. Nevertheless, ‘long-COVID’ is conceptualized as a multi-organ disorder with a wide spectrum of clinical manifestations that may be indicative of underlying pulmonary, cardiovascular, endocrine, hematologic, renal, gastrointestinal, dermatologic, immunological, psychiatric, or neurological disease. Involvement of the central or peripheral nervous system is noted in more than one-th
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El-Arif, George, Shaymaa Khazaal, Antonella Farhat, et al. "Angiotensin II Type I Receptor (AT1R): The Gate towards COVID-19-Associated Diseases." Molecules 27, no. 7 (2022): 2048. http://dx.doi.org/10.3390/molecules27072048.

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The binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein to its cellular receptor, the angiotensin-converting enzyme 2 (ACE2), causes its downregulation, which subsequently leads to the dysregulation of the renin–angiotensin system (RAS) in favor of the ACE–angiotensin II (Ang II)–angiotensin II type I receptor (AT1R) axis. AT1R has a major role in RAS by being involved in several physiological events including blood pressure control and electrolyte balance. Following SARS-CoV-2 infection, pathogenic episodes generated by the vasoconstriction, proinfla
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Cheah, Jean Mun, Jia Miao Tan, Dorothy Maria, and Siew Hui Foo. "FROM PANIC DISORDER TO CARCINOID SYNDROME IN AN EXPECTING MOTHER." Journal of the ASEAN Federation of Endocrine Societies 40, S1 (2025): 34–35. https://doi.org/10.15605/jafes.040.s1.054.

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INTRODUCTION/BACKGROUND Carcinoid syndrome occurs in ~10% of neuroendocrine tumours (NET). It indicates advanced disease with liver metastasis associated with lower survival. However, it is often misdiagnosed as other gastrointestinal, respiratory or dermatologic conditions, with a median delay in diagnosis of 3.4 years because of its rarity. CASE We present a case of a 32-year-old female at 10 weeks gestation presenting with abdominal distension. Physical examination revealed hepatomegaly and a pansystolic murmur. Ultrasound showed an enlarged liver with multiple solid lesions. Liver biopsy c
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Casal Moura, M., M. Baqir, Y. Tandon, et al. "POS1377 LUNG INVOLVEMENT IN VEXAS SYNDROME." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1028.1–1028. http://dx.doi.org/10.1136/annrheumdis-2022-eular.5232.

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BackgroundVacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome is a recently identified disorder caused by somatic mutations in the UBA1 gene of myeloid cells. Various manifestations of pulmonary involvement have been reported, but a detailed description of lung involvement and radiologic findings is lacking.ObjectivesTo describe lung involvement in VEXAS syndrome.MethodsA retrospective cohort study was conducted of all patients identified at the Mayo Clinic with VEXAS syndrome since October 2020. Clinical records and chest high resolution computed tomography (HRCT) scans
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León-Sánchez, Germán Andrés, Heiler Lozada-Ramos, Jorge Enrique Daza-Arana, Andrés Darío Restrepo-Becerra, and Ruben Varela-Miranda. "Ecthyma Gangrenosum of Fungal Origin: A Case Report." Case Reports in Dermatology 16, no. 1 (2024): 240–47. http://dx.doi.org/10.1159/000542105.

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Introduction: Ecthyma gangrenosum (EG) is usually a dermatologic manifestation of a Pseudomonas aeruginosa infection in an immunocompromised individual but may sometimes be caused by other bacteria or fungi in an immunocompromised or non-immunocompromised individual. Case Presentation: A 75-year-old woman with a history of high blood pressure and sequels of ischemic cerebral infarction presented with a 5-day history of general malaise, cough with yellow sputum, and respiratory distress. The patient had pale mucous membranes, temperature of 38.5°C, tachycardia, normal blood pressure, SaO<sub
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TUNAKAN DALGIÇ, Ceyda, Aytül Zerrin Sin, and Fatma Ömür Ardeniz. "Retrospective Analysis of Autoimmune Diseases and Immunologic Characteristics of the Adult Primary Immune Deficiency Cohort: 17 Years Experience of the Tertiary Referral Immunology Center in Turkey." Asthma Allergy Immunology 19, no. 1 (2021): 12–23. http://dx.doi.org/10.21911/aai.545.

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ABSTRACT Objective: Primary immunodeficiencies (PIDs) consist of genetically heterogeneous disorders. The spectrum can include infectious diseases, malignancy, allergy, and autoimmunity. We aimed to analyze the frequency and variety of autoimmune diseases (ADs) in PIDs and describe their clinical and laboratory features. Materials and Methods: Ninety-two patients with PID followed by Ege University Medical Faculty between 2000 and 2017 were enrolled in this retrospective, cross-sectional study. All patients’ medical records were reviewed using the demographic information, type of PIDs and ADs,
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Shionoya, Yoshiki, Maki Yamamoto, Katsuhisa Sunada, and Kiminari Nakamura. "Anesthetic Management of a Pediatric Patient With Cardiofaciocutaneous Syndrome." Anesthesia Progress 67, no. 1 (2020): 45–47. http://dx.doi.org/10.2344/anpr-67-01-07.

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Cardiofaciocutaneous (CFC) syndrome is a rare condition characterized by congenital heart disease, craniofacial dysmorphology, and dermatological abnormalities. CFC syndrome is one of the RASopathies, a family of syndromes that also includes Noonan and Costello syndromes, all with underlying gene mutations involving the Ras/mitogen-activated protein kinase pathways. Important considerations for anesthesiologists caring for these patients include the need to evaluate for possible cardiac defects, anticipating and planning for potentially difficult airway management, and the consideration of pot
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Soneji, Maulin, John Tan, and Emily Wong. "662. Using Machine Learning to Aid in the Diagnosis of Multisystem Inflammatory Syndrome in Children." Open Forum Infectious Diseases 8, Supplement_1 (2021): S433. http://dx.doi.org/10.1093/ofid/ofab466.859.

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Abstract Background Multisystem inflammatory syndrome in children (MIS-C) is a newly recognized inflammatory syndrome that occurs post Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) infection. It affects multiple organ systems - particularly cardiac, gastrointestinal, dermatologic and neurologic. Clinicians may have difficulty diagnosing MIS-C due to its novelty and similarity to Kawasaki disease. Our goal was to use machine learning to predict whether children would have MIS-C based on symptoms and laboratory values. Methods A retrospective review was conducted of patients admit
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Rezende, Hudson Dutra, Maria Fernanda Reis Gavazzoni Dias, Antonia Régnier, Natalia Caballero Uribe, and Ralph Michel Trüeb. "A Comment on Coronavirus Disease 2019 and the Hair." International Journal of Trichology 16, no. 1 (2024): 1–5. https://doi.org/10.4103/ijt.ijt_179_20.

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ABSTRACT The novel viral pandemic coronavirus disease 2019 (COVID-19) has sparked uncertainties and controversies as to its origin, epidemiology, and natural course. In this situation, the medical disciplines strive to contribute to a better understanding of the disease with the best available evidence gained from the scientific method of observation and statistics. The study of the cutaneous manifestations of COVID-19 has evolved with the hope that they may be useful as markers for the disease, for prognostication, and further insights into the pathogenesis of the disease manifestations. With
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Li, Jing, Yan Wang, Chad Tang, et al. "Concurrent nivolumab and ipilimumab with brain stereotactic radiosurgery for brain metastases from non-small cell lung cancer: A phase I trial." Journal of Clinical Oncology 38, no. 15_suppl (2020): 2531. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.2531.

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2531 Background: Nivolumab (nivo) and ipilimumab (ipi) were found in the recent phase III CheckMate 227 trial to have an overall survival benefit over chemotherapy for advanced non-small cell lung cancer (NSCLC). However, patients (pts) with untreated brain metastasis (mets) were excluded from that trial. Because 30% of NSCLC pts develop brain mets, we tested nivo/ipi with concurrent stereotactic radiosurgery (SRS) for NSCLC pts with active brain mets. Methods: We report the safety data from the phase I portion of an ongoing phase I/II single-institution trial in which one treatment group was
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McGuire, Joseph, and Saif Al-Qatarneh, MD. "Cardio-Facio-Cutaneous Syndrome with an Unusual Presentation of Respiratory Failure Requiring Tracheostomy and Long-term Ventilation." West Virginia Medical Journal 119, no. 4 (2023): 16–17. http://dx.doi.org/10.21885/wvmj.2023.18.

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Cardio-facio-cutaenous (CFC) syndrome is a phenotypically diverse disorder that is caused by mutations in the RAS/MEK/ERK signaling pathway, sharing many clinical similarities with Noonan and Costello syndromes. Classic findings of CFC include congenital cardiac anomalies, dysmorphic facial features, dermatological manifestations, and other multisystemic abnormalities. Laryngomalacia, generalized muscle weakness, and hypotonia have been reported phenotypical variants of the disorder. We describe a case of a male newborn with a genetic diagnosis of CFC syndrome who presented with respiratory fa
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Khondker, Lubna, Md Shirajul Islam Khan, and Abu Reza Sayem Ahamed. "Dermatological Manifestations of COVID-19 Patients." International Journal of Advanced Multidisciplinary Research and Studies 4, no. 3 (2024): 186–90. http://dx.doi.org/10.62225/2583049x.2024.4.3.2762.

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Background: COVID-19 is a highly contagious respiratory tract infection caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), was first identified in China, in December 2019. Almost 10% of the patients develop dermatological manifestations before the onset of respiratory illness, with cutaneous signs that can appear from before to several days after the diagnosis of COVID-19. We believe that the dermatologist can play an important role through early recognition of skin lesions suggestive of COVID-19, particularly in asymptomatic infections where this recognition could direct
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Sharma, Rohini, and Sameer Abrol. "Cutaneous adverse effects following COVID 19 precaution taking measures." IP Indian Journal of Clinical and Experimental Dermatology 8, no. 1 (2022): 8–11. http://dx.doi.org/10.18231/j.ijced.2022.002.

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The outbreak of a mysterious pneumonia, reported from a sea food wet market of Wuhan, Hubei, China in 2019 has now taken the shape of a pandemic with successive waves sweeping across nations and creating havoc. Moreover, the transmission speed is much more than earlier severe acute respiratory syndrome coronavirus (SARS) and Middle East respiratory syndrome coronavirus (MERS) making it imperative for the use of protective gears like masks, gloves and personal protective equipment(PPE) kits but ironically they in itself lead to a range of cutaneous complications making it difficult to continuou
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M., Dheemant, Sushmitha E. S., Madhan Jeyaraman, Ajay S. S., and Rashmi Jain. "Unveiling the dermatological manifestations of nCOVID-19." International Journal of Research in Dermatology 6, no. 4 (2020): 597. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20202024.

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<p class="abstract">Coronaviruses are RNA viruses that have become a major public health concern since the severe acute respiratory syndrome CoV (SARS-CoV-2) outbreak in 2002. The continuous evolution of coronaviruses was further highlighted with the emergence of the middle east respiratory syndrome CoV (MERS-CoV) outbreak in 2012. The spike glycoprotein of SARS-CoV-2 plays a pivotal role in the entry of virus into the cell and it further interacts with ACE-II receptors which are widely distributed on the human cell surface especially on alveolar type II cells (AT-2) and endothelium. Cur
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Nemchaninova, O. B., and Е. P. Simonova. "Dermatological manifestations associated with a novel coronavirus infection in the acute and post-acute period of COVID-19." Journal of Siberian Medical Sciences 7, no. 1 (2023): 7–17. http://dx.doi.org/10.31549/2542-1174-2023-7-1-7-17.

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Introduction. Dermatological manifestations of a novel coronavirus infection caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are observed in the different periods of the disease, and can sometimes be the only manifestation of coronavirus disease 2019 (COVID-19). Despite the fact that at present the daily increase in new cases of coronavirus infection in the Russian Federation is small, the issues of timely diagnosis, treatment and prevention of COVID-19 remain relevant, and the experience gained during the pandemic is of invaluable practical importance. Aim. Evaluati
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Markiewicz-Gospodarek, Agnieszka, Paulina Wdowiak, Marcin Czeczelewski, et al. "The Impact of SARS-CoV-2 Infection on Fertility and Female and Male Reproductive Systems." Journal of Clinical Medicine 10, no. 19 (2021): 4520. http://dx.doi.org/10.3390/jcm10194520.

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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remains a huge challenge for contemporary healthcare systems. Apart from widely reported acute respiratory distress syndrome (ARDS), the virus affects many other systems inducing a vast number of symptoms such as gastrointestinal, neurological, dermatological, cardiovascular, and many more. Currently it has also been hypothesized that the virus might affect female and male reproductive systems; SARS-CoV-2 infection could also have a role in potential disturbances to human fertility. In this article, we aimed to review t
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Forsyth, Alyssa, Wenqin Du, Marshall Hall, Michael Carletti, and Stephen Weis. "Challenges in Public Health: The Diagnosis and Treatment of Crusted Scabies." SKIN The Journal of Cutaneous Medicine 9, no. 2 (2025): 2184–98. https://doi.org/10.25251/skin.9.2.4.

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Introduction: Common scabies is a parasitic dermatologic condition that often presents as an extremely pruritic rash. A rare and highly contagious variant of common scabies is crusted scabies, formerly known as Norwegian scabies. While infection with common scabies typically involves 10 to 20 mites, individuals with crusted scabies are burdened with thousands to millions of mites. Crusted scabies is characterized clinically by hyperkeratotic papules and plaques, most commonly on the palms and soles. Due to the variety of presentations seen in scabies, it can be difficult to diagnose. Case Pres
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Mukurala, Swathi, Jahanavi Bandla, and Swetha kappala. "Angioedema-post COVID symptoms." AIMS Allergy and Immunology 7, no. 4 (2023): 273–80. http://dx.doi.org/10.3934/allergy.2023018.

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<abstract> <p>The non-respiratory symptoms associated with coronavirus disease 2019 (COVID-19) are being reported more frequently as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads throughout the world. Numerous dermatological issues have been connected to this viral infection. Angioedema has been reported by the patients post COVID. In this article, we discuss cases that have been reported in the medical literature and give a case study of angioedema that might be because of COVID-19 infection.</p> </abstract>
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Noure, Lamya, Kirley Küçük, Sylvain Raoul Simeni Njonnou, Véronique Del Marmol, Jonathan M. White, and Benjamin Bondue. "Respiratory Distress Syndrome Associated with Erythrodermic Psoriasis." Case Reports in Dermatology 13, no. 1 (2021): 83–88. http://dx.doi.org/10.1159/000511368.

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Erythrodermic psoriasis is an uncommon and severe variant of psoriasis which may be associated with rare and severe complications such as acute respiratory distress syndrome. Early recognition of this life-threatening condition can allow prompt appropriate treatment. We report the case of a 69-year-old man with a long history of psoriasis who developed acute respiratory distress during a disease flare-up. There was no relevant past history (except for mild emphysema), known allergy, or recent treatment. Chest X-ray revealed new bilateral infiltrates, confirmed at chest computed tomography scan
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Sitaresmi, Adya, and Lita Setyowatie. "CORONAVIRUS DISEASE 2019 (COVID-19) DARI PERSPEKTIF DERMATOLOGI." Jurnal Klinik dan Riset Kesehatan 1, no. 1 (2021): 33–40. http://dx.doi.org/10.11594/jk-risk.01.1.4.

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Coronavirus Disease 2019 (COVID-19) merupakan penyakit baru yang terjadi akibat infeksi virus Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Manifestasi klinis umumnya berupa gangguan sistem respirasi. Namun, COVID-19 juga dapat bermanifestasi sebagai gejala ekstraparu, salah satunya dermatologi. Mekanisme pasti terjadinya manifestasi kulit pada COVID-19 masih belum dipahami secara penuh, namun diduga disebabkan oleh efek langsung virus terhadap sel keratinosit, respon imun berlebihan, maupun karena obat-obatan yang digunakan untuk tatalaksana COVID-19. Manifestasi kulit dari CO
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Ang, BCH, MIC Chen, TLH Goh, YY Ng, and SW Fan. "An Assessment of Electronically Captured Data in the Patient Care Enhancement System (PACES) for Syndromic Surveillance." Annals of the Academy of Medicine, Singapore 34, no. 9 (2005): 539–44. http://dx.doi.org/10.47102/annals-acadmedsg.v34n9p539.

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Introduction: A common approach to the surveillance of emerging infectious diseases and agents of bioterrorism is to analyse electronically captured data for disease syndromes. The Patient Care Enhancement System (PACES) is a form of electronic medical records presently in service in the Singapore Armed Forces (SAF). We assess the feasibility of PACES data for surveillance, describe time-trends, and identify methods of sub-analysis which could improve performance. Materials and Methods: Medical consults from July 2000 to June 2003 were extracted. Diagnosis codes were mapped to 7 infectious dis
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Chandni P. Daryanani, Theresia Monica Rahardjo, Harris Utama, Angga Trie Buana, Eaufira Mereditha Pasaribu, and Euodia Eunike. "Multisystem Inflammatory Syndrome in Children: A Review." Medical Clinical Update 2, no. 1 (2023): 19–23. http://dx.doi.org/10.58376/mcu.v2i1.26.

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Pediatric inflammatory multisystem syndrome, temporally associated with SARS-CoV-2 (PIMS-TS) or multisystem inflammatory syndrome in children (MIS-C) is a condition identified recently. Children who were previously healthy may experience cardiac, neurological, respiratory, gastrointestinal, and dermatological dysfunction. Majority of patients (73%) require intensive care treatment, and more than half (56%) of patients arrive in shock. Different management are used for MIS-C patients, but they all primarily focus on immunomodulatory drugs such as IVIG and glucocorticoids as initial therapy. Bio
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Ali, Zara, and Navneet Kalsi. "P032 Prevalence and severity of dermatological symptoms experienced after critical care admission: an observational study." British Journal of Dermatology 191, Supplement_1 (2024): i28—i29. http://dx.doi.org/10.1093/bjd/ljae090.059.

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Abstract Recent medical advances mean that more people survive critical illnesses and intensive care unit (ICU) admissions. This has led to an uptick in reported physical, cognitive and mental health issues post-ICU (Hiser SL, Fatima A, Ali M et al. Post-intensive care syndrome (PICS): recent updates. J Intensive Care 2023; 11: 23). Despite existing research, dermatological symptoms post-ICU care have been overlooked. This study aims to assess the prevalence and extent of such symptoms in patients 1 month after ICU admission. Local approval was obtained for the study. We enrolled ICU patients
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Eghbal Lahooran, Oilinia Bordovski, and Bonesch Tiora. "Extra-pulmonary manifestations of COVID-19: A comprehensive review." World Journal of Advanced Research and Reviews 23, no. 3 (2024): 562–69. http://dx.doi.org/10.30574/wjarr.2024.23.3.2720.

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The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has predominantly been recognized for its respiratory impact. However, as the pandemic has progressed, it has become evident that SARS-CoV-2 affects multiple organ systems beyond the lungs, resulting in a wide array of extra-pulmonary manifestations. These manifestations encompass cardiovascular, neurological, gastrointestinal, hepatic, renal, dermatological, hematological, endocrine, musculoskeletal, ocular, immunological, and psychiatric complications. This review aims to provide a comprehensiv
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Eghbal, Lahooran, Bordovski Oilinia, and Tiora Bonesch. "Extra-pulmonary manifestations of COVID-19: A comprehensive review." World Journal of Advanced Research and Reviews 23, no. 3 (2024): 562–69. https://doi.org/10.5281/zenodo.14928879.

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The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has predominantly been recognized for its respiratory impact. However, as the pandemic has progressed, it has become evident that SARS-CoV-2 affects multiple organ systems beyond the lungs, resulting in a wide array of extra-pulmonary manifestations. These manifestations encompass cardiovascular, neurological, gastrointestinal, hepatic, renal, dermatological, hematological, endocrine, musculoskeletal, ocular, immunological, and psychiatric complications. This review aims to provide a comprehensiv
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Al-NIAIMI, Firas, and Calum C. LYON. "Erythrodermic psoriasis complicated by acute respiratory distress syndrome." European Journal of Dermatology 21, no. 3 (2011): 429–30. http://dx.doi.org/10.1684/ejd.2011.1303.

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Soltani, Marziyeh, Fatemeh Abdi, and Somayeh Shahsavari. "Exploring Dermatological Complications of Drugs Used in Acute Respiratory Syndrome Coronavirus 2 Treatment: A Mini Review." Journal of Biochemicals and Phytomedicine 3, no. 1 (2024): 8–13. https://doi.org/10.34172/jbp.2024.4.

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The COVID-19 pandemic has presented unprecedented challenges to governments and populations worldwide, triggering a global health crisis within months. In response, international health research organizations have highlighted various effects of chemical therapies, including dermatological complications. This mini-review explores the dermatological effects of drugs used in the treatment of COVID-19. This study examines the skin manifestations resulting from standard chemical treatments administered during the COVID-19 pandemic. Keywords were cross-referenced across multiple databases, including
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Dosedla, Erik, Petra Gašparová, Zuzana Ballová, Kamila Radaljová, and Pavel Calda. "Epidermolysis in a newborn of a mother affected by covid-19 in the 3rd trimester of pregnancy." Česká gynekologie 88, no. 1 (2023): 13–16. http://dx.doi.org/10.48095/cccg202313.

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Covid-19, caused by severe respiratory syndrome coronavirus 2 (SARS-CoV-2), is currently a pandemic. Although this infection primarily presents with respiratory symptoms, the number of reported extrapulmonary manifestations, including dermatological, is also increasing. A group of pregnant women is particularly susceptible to respiratory diseases, but with regard to covid-19, there is still limited data on the course of infection in pregnancy in relation to the possibility of vertical transmission. We present the case of a 30-year-old unvaccinated patient with a history of overcoming covid-19
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Błaszczyk, Agnieszka, Sara Trojan, Urszula Fussek-Styga, et al. "Sweet Syndrome - A Review of Pathogenesis, Clinical Features, Diagnosis and Treatment." Journal of Education, Health and Sport 30, no. 1 (2023): 45–56. http://dx.doi.org/10.12775/jehs.2023.30.01.004.

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Sweet syndrome is a rare, inflammatory, non-infectious skin disorder characterized by an acute onset of skin leasions such as painful, erythematous plaques, nodules and papules, most frequently located on the upper extremities, trunk, neck and face. Generally, dermatological symptoms are accompanied by fever, headaches, arthralgia and leukocytosis. The syndrome belongs to the group of febrile neutrophilic dermatoses. Skin biopsy reveals a diffuse, neutrophilic infiltrate in the upper dermis. Sweet syndrome presents in three clinical subtypes: classical, malignancy-associated and drug-induced.
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Sandriel, Dandou Ange Thomas, Biantona Léonard, Rhezali Manel, El Abou Hassan, and Nejmi Hicham. "Eosinophilic Pneumonitis Complicated by ARDS Following DRESS Syndrome: Case Report." Scholars Journal of Medical Case Reports 11, no. 03 (2023): 295–98. http://dx.doi.org/10.36347/sjmcr.2023.v11i03.012.

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Introduction: Drug reaction syndrome with eosinophilia and systemic symptoms (DRESS) is a rare and potentially fatal hypersensitivity reaction, The reaction usually manifests as a febrile skin rash accompanied by lymphadenopathy and malaise between two and eight weeks after drug exposure. The pulmonary manifestations of DRESS are variable and may include interstitial pneumonia, pleural effusion, pneumonia, pulmonary nodules and (in the most severe cases) acute respiratory distress syndrome (ARDS). We report the observation of an acute eosinophilic pneumonitis which is unique in that it is part
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Srivastava, Utkarsh, Kshitij Aviraj Singh, Animesh Sahu, and Richie Dalai. "Unveiling collodion baby: confronting ectropion and respiratory drama in neonatal care." BMJ Case Reports 17, no. 8 (2024): e261687. http://dx.doi.org/10.1136/bcr-2024-261687.

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A neonate presented to us with respiratory distress with diffuse involvement of skin with thickening, cracking and peeling since birth with severe ectropion and eclabium. The hospital course was complicated by polymicrobial sepsis requiring prolonged antibiotics and antifungals. The skin lesions were treated with acitretin, humidification and topical emollients. With the improvement of pneumonia and clearing of nasal debris, the neonate could be gradually weaned off respiratory support. Despite a stormy course, there was marked improvement in all skin lesions including ectropion and eclabium a
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Basak, RB, H. Narchi, M. Bakir, S. Joshi, and W. Conca. "Churg-strauss syndrome without respiratory symptoms in a child." Indian Journal of Dermatology 56, no. 1 (2011): 84. http://dx.doi.org/10.4103/0019-5154.77561.

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Abou-Samra, T., J.-M. Constantin, S. Amarger, et al. "Generalized pustular psoriasis complicated by acute respiratory distress syndrome." British Journal of Dermatology 150, no. 2 (2004): 353–56. http://dx.doi.org/10.1111/j.1365-2133.2004.05777.x.

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