Relevant bibliographies by topics / Desethylchloroquine

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  1. Journal articles
  2. Dissertations / Theses

Academic literature on the topic 'Desethylchloroquine'

Author: Grafiati
Published: 4 June 2021
Last updated: 11 February 2022

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Journal articles on the topic "Desethylchloroquine"

1

Ofori-Adjei, D., O. Ericsson, B. Lindstrom, and F. Sjoqvist. "Protein binding of chloroquine enantiomers and desethylchloroquine." British Journal of Clinical Pharmacology 22, no. 3 (September 1986): 356–58. http://dx.doi.org/10.1111/j.1365-2125.1986.tb02900.x.

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2

Ogunbona, FA, CO Onyeji, OO Bolaji, and SE Torimiro. "Excretion of chloroquine and desethylchloroquine in human milk." British Journal of Clinical Pharmacology 23, no. 4 (April 1987): 473–76. http://dx.doi.org/10.1111/j.1365-2125.1987.tb03078.x.

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3

Ansari, Aslam M., and J. Cymerman Craig. "Metabolites of Chloroquine:Some Observations on Desethylchloroquine andN‐Acetyldesethylchloroquine." Journal of Pharmaceutical Sciences 83, no. 7 (July 1994): 1040–42. http://dx.doi.org/10.1002/jps.2600830722.

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4

Rombo, Lars, Örjan Ericsson, Gunnar Alvän, Björn Lindström, Lars L. Gustafsson, and Folke Sjöqvist. "Chloroquine and Desethylchloroquine in Plasma, Serum, and Whole Blood." Therapeutic Drug Monitoring 7, no. 2 (June 1985): 211–15. http://dx.doi.org/10.1097/00007691-198506000-00013.

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5

Adjepon-Yamoah, K. K., D. Ofori-Adjei, N. M. Woolhouse, and B. Lindström. "Whole-Blood Single-Dose Kinetics of Chloroquine and Desethylchloroquine in Africans." Therapeutic Drug Monitoring 8, no. 2 (June 1986): 195–99. http://dx.doi.org/10.1097/00007691-198606000-00012.

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6

Ofori-Adjei, David, Örjan Ericsson, Björn Lindström, Jörgen Hermansson, Kenneth Adjepon-Yamoah, and Folke Sjöqvist. "Enantioselective Analysis of Chloroquine and Desethylchloroquine after Oral Administration of Racemic Chloroquine." Therapeutic Drug Monitoring 8, no. 4 (December 1986): 457–61. http://dx.doi.org/10.1097/00007691-198612000-00014.

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7

Ogunbona, F. A., C. O. Onyeji, A. A. Lawal, C. M. Chukwuani, and O. O. Bolaji. "Liquid chromatographic analysis of chloroquine and desethylchloroquine in human plasma, saliva and urine." Journal of Chromatography B: Biomedical Sciences and Applications 380 (January 1986): 425–30. http://dx.doi.org/10.1016/s0378-4347(00)83674-9.

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8

Law, Irwin, Kenneth F. Ilett, L. Peter Hackett, Madhu Page-Sharp, Francesca Baiwog, Servina Gomorrai, Ivo Mueller, Harin A. Karunajeewa, and Timothy M. E. Davis. "Transfer of chloroquine and desethylchloroquine across the placenta and into milk in Melanesian mothers." British Journal of Clinical Pharmacology 65, no. 5 (May 2008): 674–79. http://dx.doi.org/10.1111/j.1365-2125.2008.03111.x.

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9

Augustijns, P. "Determination of Chloroquine and Desethylchloroquine in Biological Samples Using Perfusion Chromatography and Fluorescence Detection." Journal of Liquid Chromatography & Related Technologies 20, no. 7 (April 1997): 1103–13. http://dx.doi.org/10.1080/10826079708010962.

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10

Ansari, Aslam M., and J. Cymerman Craig. "A Convenient, Short Synthesis of Desethylchloroquine [7-Chloro-4-(4’-ethylamino-1’-methyl-butylamino)quinoline]." Synthesis 1995, no. 02 (February 1995): 147–49. http://dx.doi.org/10.1055/s-1995-3886.

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Dissertations / Theses on the topic "Desethylchloroquine"

1

Botelho, Kátia Cirlene Alves. "Antimaláricos potenciais: latenciação de primaquina e desetilcloroquina e estudo da síntese de pró-fármacos peptídicos de liberação específica." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/9/9138/tde-08112016-162838/.

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Abstract:
A Malária continua sendo a mais difundida e devastadora doença infecciosa, com aproximadamente 300 milhões de casos anuais e mais de 2 milhões de pessoas vivendo em áreas de risco. Entre os parasitas do gênero plasmodium causadores da malária em humanos, o plasmodium falciparum é a espécie mais letal. Este projeto teve como objetivo a síntese de pró-fármaco recíproco de cloroquina e primaquina e de pró-fármacos duplicados de cloroquina e de primaquina utilizando, para tanto, espaçantes inespecíficos (carboxílicos). Espera-se que o pró-fármaco recíproco permita a cura radical em casos de malária vivax e que os derivados duplicados apresentem maior eficácia, com diminuição da toxicidade, especialmente no caso do derivado de primaquina. Além desses compostos, propôs-se a síntese de pró-fármacos duplicados de cloroquina mediante a ligação com grupo espaçante específico (peptídeos) à cisão pela falcipaína. Tais derivados são potencialmente ativos em malária causada pelo P. falciparum resistente à cloroquina.
Malaria remains the world\'s most widespread and devastating infectious disease, with approximately 300 million annual cases and more than 2 million casualties. Among the protozoan parasites of the genus Plasmodium causing malaria in humans, Plasmodium falciparum is the most lethal species. This project had as objective the synthesis of reciprocal prodrug of chloroqine and primaquine using, for in such a way, inespecífics agents (carboxylics). One expects that the mutual prodrug allows to the radical cure in cases of malaria vivax and that the derivatives duplicates present greater effectiveness, with reduction of the toxicity, especially in the case of the primaquine derivative. Beyond these composites, it was considered synthesis of mutual prodrugs of chloroquine by means of the linking with specific carrier group (peptides) to the split for falcipain. Such derivatives are potentially active in malaria caused for the resistant P. falciparum to the chloroquine.
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2

Kang, Jonathan Chul-Hwan [Verfasser]. "Untersuchungen über den Einfluss von Chloroquin und Desethylchloroquin auf die verschiedenen Entwicklungsstadien der Malariaerreger Plasmodium yoelii nigeriensis und Plasmodium falciparum (Coccidia: Plasmodiidae) / vorgelegt von Jonathan Chul-Hwan Kang." 2002. http://d-nb.info/966416899/34.

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Journal articles
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