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Journal articles on the topic 'Design cellule'

Author: Grafiati

Published: 20 July 2024

Last updated: 19 July 2025

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1

Vályi-Nagy, Marianna, Attila Rácz, Katalin Irmes, et al. "Evaluation of the Development Process of Winter Wheat (Triticum aestivum L.) and Winter Pea (Pisum sativum L.) in Intercropping by Yield Components." Agronomy 13, no. 5 (2023): 1323. http://dx.doi.org/10.3390/agronomy13051323.

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The future of wheat production depends on our ability to adapt to changing growing conditions. It is expected that intercropping will be more emphasized where natural source of nitrogen may increase the resilience of cereals. Our investigation was made in two growing seasons (2020–2021, 2021–2022) with three winter wheat varieties (GK Szilárd, Cellule, GK Csillag) and a winter pea variety (Aviron) in Szeged-Öthalom. Each plot was 10 square meters in four repeats in randomized block design. We used a seed mixture of both species with three sowing densities. In this study, we represent a development process of two winter-sown species, then yield components evaluated by cumulative yield production analysis and multivariate regression. Mixtures were only beneficial for wheat in the case of GK Szilárd 50% and Aviron 75%, Cellule 75% and Aviron 100% (in 2021), Cellule 100% and Aviron 50% (in 2022), GK Csillag 75% and Aviron 50%. The yield was determined by the number and weight of grains in both species (and also number of pea pods). Knowledge of the development process of the companion plants is a key issue in creating an effective intercrop. This self-sustaining, low input and energy efficient cropping practice has a great potential in temperate areas.

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Giugliano, Giovanna, Mario Buono, and Sonia Capece. "Design per configurare nuovi luoghi e spazi di apprendimento adattivi." i+Diseño. Revista Científico-Académica Internacional de Innovación, Investigación y Desarrollo en Diseño 16 (December 16, 2021): 107–24. http://dx.doi.org/10.24310/idiseno.2021.v16i.12804.

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Diseñar formas y espacios de aprendizaje es un proceso que requiere creatividad pedagógica, arquitectónica, social, cultural y política.La literatura científica nacional e internacional (OCDE, 2017) sobre innovación educativa destaca la estrecha relación que conecta la didáctica con el entorno de aprendizaje. Por ello, los procesos de renovación educativa no pueden prescindir de una nueva visión de los espacios escolares y de los entornos educativos.Surgen nuevas pautas de planificación escolar, se enfatiza el aprendizaje como un proceso activo y constructivo en el que cada niño tiene un papel «protagonista».De hecho, en el escenario contemporáneo, los estudiantes se convierten en participantes activos en la creación de información y nuevas ideas en el entorno educativo. En consecuencia, la educación del siglo XXI se basa en tres principios pedagógicos (McLoughlin & Lee, 2008): personalización, participación y productividad (Luna Scott, 2015).El estudio de estos aspectos, acompañado del análisis evaluativo y comparativo de experiencias de diseño en el ámbito escolar, nos ha permitido configurar el nuevo concepto SINAPSI 0-14, un sistema de mobiliario que adapta y adopta tecnologías avanzadas para satisfacer las necesidades de los niños y profesores, actuales y futuras, según una perspectiva holística.El objetivo era diseñar un sistema de celdas «orgánicas» modulares, flexibles y adaptables que pudieran ser utilizadas de forma transversal por usuarios de diferentes edades, desde jardines de infancia hasta centros de enseñanza primaria y secundaria. SINAPSI 0-14 se configura en formas que pertenecen a un universo de geometrías que se remontan a una única matriz de elementos orgánicos. El conjunto de símbolos que pueden agregarse definen diferentes formas del sistema de mobiliario, haciendo que el espacio educativo sea «cronotópico» y capaz de cambiar según el tiempo y el lugar que se cree y según el uso y las necesidades.Estos estudios en profundidad han permitido reconstruir un repertorio analítico crítico sobre el tema de los espacios educativos y la arquitectura escolar, entrelazando sus cambios en función de los modelos pedagógicos y los instrumentos normativos, para definir la escuela del futuro. Progettare forme e spazi di apprendimento è un processo che richiede creatività pedagogica, architettonica, sociale, culturale e politica.La letteratura scientifica nazionale e internazionale (OECD, 2017) sull’innovazione educativa evidenzia la stretta relazione che connette la didattica all’ambiente di apprendimento. Per tale ragione, i processi di rinnovamento della didattica non posso prescindere da una nuova visione degli spazi scolastici e dei setting educativi.Emergono nuove linee guida per la progettazione scolastica, si enfatizza l’apprendimento come un processo attivo e costruttivo nel quale ogni bambino ha un ruolo di “protagonista”.Difatti, nello scenario contemporaneo, gli studenti divengono partecipanti attivi alla creazione di informazioni e di nuove idee nell’ambiente educativo. Di conseguenza, l'istruzione del ventunesimo secolo si basa su tre principi pedagogici (McLoughlin & Lee, 2008): personalizzazione, partecipazione e produttività (Luna Scott, 2015).Lo studio di tali aspetti, accompagnato dall’analisi valutativa e comparativa di esperienze progettuali in campo scolastico, ha consentito di configurare il nuovo concept allestitivo SINAPSI 0-14, un sistema d’arredo che adatti e adotti le avanzate tecnologie per rispondere ai bisogni di bambini e insegnanti, attuali e futuri, secondo una prospettiva olistica.L’obiettivo è stato progettare un sistema di cellule “organiche” modulari, flessibili e adattabili che possano essere utilizzate in maniera trasversale da utenti di diverse età, dalle scuole d’infanzia alle scuole primarie e secondarie di primo grado. SINAPSI 0-14 si configura in forme appartenenti a un universo di geometrie riconducibili a un’unica matrice di elementi organici. L’insieme dei simboli aggregabili definiscono differenti forme del sistema di arredo rendendo lo spazio didattico “cronotopico” atto a modificarsi in funzione del tempo e del luogo che si crea e in funzione dell’uso e delle esigenze.Tali approfondimenti hanno consentito di ricostruire un repertorio critico analitico sul tema degli spazi educativi e delle architetture scolastiche intrecciandone i cambiamenti in linea con i modelli pedagogici e gli strumenti normativi, al fine di definire la scuola del futuro.

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Masrina, Angel Bintang, Muhammad Amin, and Pristiyanilicia Putri. "Implementasi E-CRM Untuk Meningkatkan Penjualan Produk Di Toko Matrix Celluler Berbasis Web." JUTSI (Jurnal Teknologi dan Sistem Informasi) 2, no. 2 (2022): 77–84. http://dx.doi.org/10.33330/jutsi.v2i2.1683.

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Abstract : Matrix Celluler who is on the road Prof. H.M. Yamin No.16, Kisaran Naga, Kec. Kisaran Eastern, Asahan Regency, North Sumatera namely store that process transactions in cash and credit with sales products namely Handphone Samsung, Vivo, Oppo, dan Nokia. Besides Handphone, Matrix Celluler also provide Accessories in the form of Charger, Antigores, Handsfree, and Softcase. This research was conducted with the aim of designing a new system, namely Customer Relationship Management that is attractive and effective for sales and customer service according to the needs of the store and customers, Helping Cellular Matrix give trust to customers by implementing cash, credit and COD (Cash) transaction features. On Delivery) in the system and provide solutions to increase sales revenue at Matrix Celluler stores such as implementing coin and voucher features to customers. The research method use qualitative methods with a qualitative descriptive design format with data collection techniques, namely interview, observation and library research. This system is designed using several software namely Sublime Text 3, XAMPP, PHP, dan MySQL. Keywords : Increase Sales; CRM, Design; and Website. Abstrak : Matrix Celluler yang berada di jalan Prof. H.M. Yamin No.16, Kisaran Naga, Kec. Kisaran Timur, Kabupaten Asahan, Sumatera Utara yakni sebuah toko yang melakukan proses transaksi secara cash dan kredit dengan produk penjualan yaitu Handphone Samsung, Vivo, Oppo, dan Nokia. Selain Handphone, Matrix Celluler juga menyediakan Accessories berupa Charger, Antigores, Handsfree, dan Softcase. Penelitian ini dilakukan dengan tujuan untuk merancang suatu sistem yang baru yaitu Customer Relationship Management yang menarik dan efektif untuk penjualan dan pelayanan pelanggan sesuai dengan kebutuhan pihak toko dan pelanggan, Membantu Matrix Celluler memberikan kepercayaan kepada pelanggan dengan menerapkan fitur transaksi cash, kredit dan COD (Cash On Delivery) di sistem dan memberikan solusi dalam meningkatkan hasil pendapatan penjualan di toko Matrix Celluler seperti menerapkan fitur koin dan voucher kepada pelanggan. Metode penelitian menggunakan metode kualitatif dengan format desain deskriptif kualitatif dengan teknik pengumpulan data yaitu wawancara, observasi dan penelitian kepustakaan. Sistem ini di rancang dengan menggunakan beberapa software yaitu Sublime Text 3, XAMPP, PHP, dan MySQL. Kata Kunci : Meningkatkan Penjualan; CRM; Perancangan; Website.

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Akintomide, A. A., I. B. Osho, and G. E. Onibi. "Growth performance and haematology of broiler chickens fed enzyme supplemented neem leaf meal -based diets." Nigerian Journal of Animal Production 48, no. 5 (2021): 152–64. http://dx.doi.org/10.51791/njap.v48i5.3196.

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The quest for sustainable poultry production using alternative feed ingredients is imperative. This study was conducted to assess the growth performance and blood profile of broiler chickens fed neem leaf meal (NLM) based diets with or without enzyme supplementation. Two hundred and eighty-eight, one-week old chicks (with an average weight of 98.44g) arranged in a completely randomized design with twelve birds/ replicate and three replicates/ treatment were fed NLM at 0, 1.5, 3 and 5% with or without Polyzme® to form eight experimental treatments. Data on initial body weights, weekly body weights and feed intake were taken during the trial which lasted for eight weeks and feed conversion ratio calculated. Blood was also collected for haematological studies at the 4 and 8 week by humanely severing the jugular vein. Results indicated that total weight gain at starter phase decreased progressively with increase in NLM inclusion and addition of Polyzme did not significantly (P>0.05) affect performance. At the finisher phase, growth performance was not significantly (P>0.05) influenced by NLM or enzyme addition. Furthermore, NLM with/without Polyzyme did not elicit any significant influence on the packed cell volume and haemoglobin concentration of the chickens. In conclusion, broiler chicks could tolerate up to 3% NLM and finishers up to 5% based on growth performance. The use of polyzyme at 400g/tonne in this study did not improve the utilization of NLM by the chickens.  La recherche de la production de volaille durable utilisant des ingrédients d'alimentation alternatifs est impérative. Cette étude a été réalisée pour évaluer la performance de la croissance et le profil sanguin des régimes à base de feuilles neem (NLM) avec ou sans supplémentation en enzyme. Deux cent quatre-vingt-huit poussins âgés d'une semaine (avec un poids moyen de 98,44 g) disposés dans un design complètement randomisé avec douze oiseaux / répliqués et trois répliqués / traitement ont été nourris à 0, 1,5, 3 et 5% avec ou sans Polyzme pour former huit traitements expérimentaux. Les données sur les poids corporels initiaux, les poids corporels hebdomadaires et l'apport alimentaire ont été pris au cours de l'essai qui a duré huit semaines et le ratio de conversion alimentaire calculé. Le sang a également été collecté pour des études hématologiques à la 4ème et 8ème semaine en coupant humainement la veine jugulaire. Les résultats ont indiqué que le gain de poids total à la phase de démarrage a diminué progressivement avec l'augmentation de l'inclusion de NLM et l'addition de polyzme n'a pas significativement (p> 0,05) affecter les performances. À la phase de finition, la performance de la croissance n'était pas significativement (p> 0,05) influencée par l'addition NLM ou enzyme. De plus, la NLM avec / sans polyzyme n'a suscité aucune influence significative sur le volume de la cellule emballé et la concentration en hémoglobine des poulets. En conclusion, les poussins de chair pourraient tolérer jusqu'à 3% de NLM et des finisseurs jusqu'à 5% sur la base de la performance de la croissance. L'utilisation de polyzyme à 400 g / tonne dans cette étude n'a pas amélioré l'utilisation de NLM par les poulets.

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5

Dhiman, Rajni, and Puneet Utreja. "DESIGN AND CHARACTERIZATION OF AMLODIPINE BESYLATE TRANSDERMAL PATCHES USING HYDROXY PROPYL METHYL CELLULOSE AND ETHYL CELLULOSE COMBINATION." INDIAN RESEARCH JOURNAL OF PHARMACY AND SCIENCE 7, no. 4 (2020): 2415–31. http://dx.doi.org/10.21276/irjps.2020.7.4.3.

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6

Bahrepour, Davoud. "A Novel Full Comparator Design Based on Quantum-Dot Cellular Automata." International Journal of Information and Electronics Engineering 5, no. 6 (2015): 406–10. http://dx.doi.org/10.7763/ijiee.2015.v5.568.

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7

Nozari, Mehrnaz, and Hamed Nahr. "ENGINEERING CELLULAR HARMONY: A COMPREHENSIVE LITERATURE REVIEW ON CELL PRODUCTION SYSTEM DESIGN." American Journal of Management and Economics Innovations 6, no. 1 (2024): 6–11. http://dx.doi.org/10.37547/tajmei/volume06issue01-02.

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This literature review delves into the intricate domain ofcell production system design, offering a comprehensive exploration of the methodologies, technologies, and advancements that contribute to engineering cellular harmony. The study synthesizes key findings from a broad spectrum of research, providing insights into the diverse strategies employed in designing cell production systems. By analyzing current trends, challenges, and future directions, this review aims to guide researchers, engineers, and practitioners in advancing the field of cell production system design.

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Moh., Awaludin Adam, and Maftuch. "CONDITION TOTAL LEUKOCYTES AND PLASMA PROTEIN KOI FISH (Cyprinus carpio Koi) POST SOAKING EXTRACT GRACILARIA VERRUCOSA INFECTED BACTERIA Aeromonas salmonicida." Samakia: Jurnal Ilmu Perikanan 8, no. 1 (2017): 11–18. https://doi.org/10.5281/zenodo.556715.

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The study was conducted to determine total leucocyte and plasma protein of infected Koi (<em>Cyprinus carpio</em>) after immersion in the extract of Gracillaria verrucosa. The experimental design of this research was Completely Randomized Design. Different doses of extract were used five treatments and three replicates. Data was analyzed by using ANOVA (one-way) there were significant different of total leucocyte. Total protein plasma at treatments of fish infected, showed protein of ben thinner. Doses immersion treatments at 19 ppm get significant effects of humoral and celluler system the infected of Koi.

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Shahidinejad, Ali, Ali Farrokhtala, Saman Asadi, Maryam Mofarrahi, and Toni Anwar. "A Novel Quantum-Dot Cellular Automata XOR Design." Advanced Materials Research 622-623 (December 2012): 545–50. http://dx.doi.org/10.4028/www.scientific.net/amr.622-623.545.

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Quantum-dot cellular automata (QCA) is an emerging nanotechnology that promises faster speed, smaller size, and lower power consumption compared to the transistor-based technology. Moreover, XOR is a useful component for the design of many logical and functional circuits. This paper proposes a novel and efficient QCA XOR design. The proposed XOR design has been compared to a few recent designs in terms of area, speed and complexity. Comparison of results illustrates significant improvements in our design as compared to traditional approaches. Also simulation proves that the proposed XOR design is completely robust and more sustainable to high input frequency as compared to other designs. This robustness is highly significant when this component is applied for realizing larger designs.

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Aiba, Yuichiro, Gerardo Urbina, Masanari Shibata, and Osami Shoji. "Investigation of the Characteristics of NLS-PNA: Influence of NLS Location on Invasion Efficiency." Applied Sciences 10, no. 23 (2020): 8663. http://dx.doi.org/10.3390/app10238663.

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Peptide nucleic acid can recognise sequences in double-stranded DNA (dsDNA) through the formation of a double-duplex invasion complex. This double-duplex invasion is a promising method for the recognition of dsDNA in cellula because peptide nucleic acid (PNA) invasion does not require the prior denaturation of dsDNA. To increase its applicability, we developed PNAs modified with a nuclear localisation signal (NLS) peptide. In this study, the characteristics of NLS-modified PNAs were investigated for the future design of novel peptide-modified PNAs.

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De Roos, Albert D. G. "A Proposed Framework for Cellular Evolution." Communications of the Blyth Institute 1, no. 1 (2018): 5–12. http://dx.doi.org/10.33014/issn.2640-5652.1.1.deroos.1.

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   This article shows how a good understanding of the design principles that underlie life is crucial in understanding its evolution. It gives concrete examples on how designs can be applied to evolution in the same way an engineer uses designs in creating building or bridges, or a software engineer that designs programs that can evolve. If we apply the notion of a design for evolution and realize that it is in its basis an evolving system of molecular machines, we can start to reverse engineer evolution and understand life. This article shows scenario’s for the origin of life and cel- lular life and how eukaryotic cells evolved to multicellular organisms. The driving force for evolution would be the intrinsic capability of the molecular machines to evolve and this basic tendency to evolve its ultimate goal. The scenarios that can be deduced following a design framework are drastically different from the theories that have been proposed so far. Based on the premise that that evolution can be modeled on a design framework, we can deduce that life evolved inside-out and that ontology reflects phylogeny on a molecular basis  

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Mottin, Stéphane. "Cytométrie en mode femtoseconde." Morphologie 85 (March 29, 2001): 27–28. https://doi.org/10.5281/zenodo.439018.

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Deux grandes voies de cytométrie sont habituellement distinguées: - cytométrie en flux où les cellules sont analysées à grande vitesse ; - la cytométrie en image, en particulier sur microscope confocal avec analyse d image morphologique intra-cellulaire avec balayage monopoint ou multipoint. Un des points clé des dispositifs optiques associés reste la source lumineuse. Celle-ci est généralement un laser sauf en microscopie confocale bien que dans ce domaine, les nouvelles microscopies fs se développent très rapidement. Les technologies des systèmes fs seront abordées de manière didactique pour cerner les intérêts de ces technologies, sources/systèmes/détecteurs en particulier pour la cytométrie en image. Dans le domaine de la cytométrie, l optique ultra-brève émerge actuellement grâce à la première génération des systèmes exploitant la fluorescence dite à deux photons. Auparavant de nombreux phénomènes linéaires ont été exploités : absorption, diffusion, méthodes diffractives, méthodes interférométriques, fluorescence à un photon, pression de radiation, photochimie, photolyse... Depuis quelques années l utilisation des phénomènes d optique non-linéaire apporte de grandes avancées techniques comme la fluorescence multiphotonique, la génération de deuxième et troisième harmonique, les effets paramétriques...

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Morant, Laura, Maria-Luise Petrovic-Erfurth, and Albena Jordanova. "An Adapted GeneSwitch Toolkit for Comparable Cellular and Animal Models: A Proof of Concept in Modeling Charcot-Marie-Tooth Neuropathy." International Journal of Molecular Sciences 24, no. 22 (2023): 16138. http://dx.doi.org/10.3390/ijms242216138.

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Investigating the impact of disease-causing mutations, their affected pathways, and/or potential therapeutic strategies using disease modeling often requires the generation of different in vivo and in cellulo models. To date, several approaches have been established to induce transgene expression in a controlled manner in different model systems. Several rounds of subcloning are, however, required, depending on the model organism used, thus bringing labor-intensive experiments into the technical approach and analysis comparison. The GeneSwitch™ technology is an adapted version of the classical UAS-GAL4 inducible system, allowing the spatial and temporal modulation of transgene expression. It consists of three components: a plasmid encoding for the chimeric regulatory pSwitch protein, Mifepristone as an inducer, and an inducible plasmid. While the pSwitch-containing first plasmid can be used both in vivo and in cellulo, the inducible second plasmid can only be used in cellulo. This requires a specific subcloning strategy of the inducible plasmid tailored to the model organism used. To avoid this step and unify gene expression in the transgenic models generated, we replaced the backbone vector with standard pUAS-attB plasmid for both plasmids containing either the chimeric GeneSwitch™ cDNA sequence or the transgene cDNA sequence. We optimized this adapted system to regulate transgene expression in several mammalian cell lines. Moreover, we took advantage of this new system to generate unified cellular and fruit fly models for YARS1-induced Charco–Marie–Tooth neuropathy (CMT). These new models displayed the expected CMT-like phenotypes. In the N2a neuroblastoma cells expressing YARS1 transgenes, we observed the typical “teardrop” distribution of the synthetase that was perturbed when expressing the YARS1CMT mutation. In flies, the ubiquitous expression of YARS1CMT induced dose-dependent developmental lethality and pan-neuronal expression caused locomotor deficit, while expression of the wild-type allele was harmless. Our proof-of-concept disease modeling studies support the efficacy of the adapted transgenesis system as a powerful tool allowing the design of studies with optimal data comparability.

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Arsent’ev, M. Yu, S. V. Balabanov, M. M. Sychev, and D. S. Dolgin. "Crystalline Design of Cellular Materials." Glass Physics and Chemistry 46, no. 6 (2020): 657–60. http://dx.doi.org/10.1134/s1087659620060024.

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RAJAMANI*, D., N. SINGH, and Y. P. ANEJA. "Design of cellular manufacturing systems." International Journal of Production Research 34, no. 7 (1996): 1917–28. http://dx.doi.org/10.1080/00207549608905004.

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Irani, S. A., P. H. Cohen, and T. M. Cavalier. "Design of Cellular Manufacturing Systems." Journal of Engineering for Industry 114, no. 3 (1992): 352–61. http://dx.doi.org/10.1115/1.2899803.

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This paper describes a method for layout design of a Cellular Manufacturing System (CMS) that would allow simultaneously, the grouping of machines unique to a part family into cells and those shared by several cells to be located together in functional sections. Using an illustrative example, this integration of the flexibility of a functional layout, the reduced handling gained from cell formation and allowance of limited intercell flows among adjacent cells is described. Thereby, the traditional strategy of simultaneous formation of part families and distribution of machines into independent cells which creates machine distribution and unbalanced utilization problems is avoided. This is justified by an analysis of the complex interactions between the critical subproblems in cell formation—machine grouping, part family formation, distribution and utilization of shared machines, intracell layout, intercell (or shop) layout and material handling. This approach represents a new direction in cell formation where, by allowing the handling function to limit the extent of machine duplication between adjacent cells, a new graph theoretic structure for simultaneous machine grouping and layout design was developed and validated.

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Wells, A. J. "Cellular Facility Design Made Easy." IFAC Proceedings Volumes 23, no. 3 (1990): 341–45. http://dx.doi.org/10.1016/s1474-6670(17)52580-x.

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Krakauer, David C., Lydia Müller, Sonja J. Prohaska, and Peter F. Stadler. "Design specifications for cellular regulation." Theory in Biosciences 135, no. 4 (2016): 231–40. http://dx.doi.org/10.1007/s12064-016-0239-5.

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Kita, E., and T. Toyoda. "Structural design using cellular automata." Structural and Multidisciplinary Optimization 19, no. 1 (2000): 64–73. http://dx.doi.org/10.1007/s001580050086.

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BARBÉ, ANDRÉ. "NECESSITY FROM CHANCE: SELF-ORGANIZED REPLICATION OF SYMMETRIC PATTERNS THROUGH SYMMETRIC RANDOM INTERACTIONS." International Journal of Bifurcation and Chaos 19, no. 04 (2009): 1185–225. http://dx.doi.org/10.1142/s0218127409023585.

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We present an algorithm, completely random in nature, that, without invoking a fitness function or purposeful design, produces symmetric replicas in a population of so-called cellicules. Cellicules consist of "cells" arranged in a structure with geometric symmetry S. Each cell has one of two possible states, thus defining a state-configuration pattern on a cellicule. The algorithm acts recurrently on a population of cellicules, possibly randomly initialized, through a random "copying interaction" between two randomly selected cellicules that first undergo a random reorientation in accordance with the symmetry S. The dynamics of the algorithm is analyzed in detail for several symmetries. This shows that it is a random walk with absorbing states which correspond to a population in which all cellicules have an identical S-symmetric configuration pattern. We discuss some aspects concerning the evolution of cellicule-populations under mixing and mutation, and some variations on the basic algorithm.

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Kim, Ho-Soo, and Min-Ho Lee. "Optimal Shape Design of Space Truss Structure using Topology Optimization and Cellular Automata Model." Journal of the Computational Structural Engineering Institute of Korea 25, no. 1 (2012): 73–80. http://dx.doi.org/10.7734/coseik.2012.25.1.073.

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Tayo, G. O., O. O. Olufayo, M. D. Olumide, and A. O. Akintunde. "Growth and haematological parameters of Isa-brown pullets fed Phyllanthus niruri leaf meal as additive at the chick phase." Nigerian Journal of Animal Production 49, no. 2 (2022): 130–39. http://dx.doi.org/10.51791/njap.v49i2.3470.

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Phyllanthus niruri Linn. is an erect annual herb known for its medicinal values; thus, this study was conducted to determine the effect of graded levels of Phyllanthus niruri leaf meal (PNLM) as a substitute antibiotic feed additive on the performance and haematological parameters of pullets at the chicks phase. Four hundred and eighty, 4 weeks old pullets weighing between 204.38 - 215.63g were fed diets containing Phyllanthus niruri leaf meal for 35 days in a completely randomized design experimental layout. Treatments were: T1(0% PNLM), T2 (antibiotics), T3 (0.2%PNLM), T4 (0.3%PNLM), T5 (0.4%PNLM) and T6 (0.5%PNLM) replicated four times at 20 birds per replicate. The parameters investigated were feed intake, final weight, weight gain, feed conversion ratio, mortality, and blood profiles. The final weight of pullets fed 0.5%PNLM (552.50g) were significantly higher (p<0.05) than those on T1(0%PNLM) diet (530g). There was significant differences (p<0.05) in the haematology and serum parameters recorded among the treatments. Highest packed cell volume and haemoglobin concentrations of 32% and 10.9g/100 ml, respectively, was recorded in T4 (0.3%PNLM). The highest value (27 µ/l) of ALTwas recorded in birds fed T6 (diet with 0.5%PNLM) and the least (16µ/l) in those on T5 (diet with 0.4%PNLM) and T1 (control diet). Inclusion of PNLM resulted in better weight gain in birds fed T6 (345g), average daily feed intake (46.03g/day/bird) in T4, feed conversion ratio (0.28) in T6 compared to T1(0% PNLM) and those treated with antibiotics (T2). Therefore, Phyllanthus niruri leaf meal may be considered as a potential alternative feed additives for layer chicken production at the chick's phase.    Phyllanthus niruri Linn. est une herbe annuelle dressée connue pour ses valeurs médicinales; Ainsi, cette étude a été menée pour déterminer l'effet des niveaux de graduation du repas de feuille de niruri Phyllanthus (RFNP) en tant qu'additif d'alimentation antibiotique substitué sur les performances et les paramètres hématologiques des poulettes à la phase des poussins. Quatre cent quatre-vingt, 4 semaines de poulettes pesant entre 204,38 et 215,63 g étaient des régimes alimentaires contenant un repas de feuille de Phyllanthus niruri pendant 35 jours dans une structure expérimentale de conception entièrement randomisée. Les traitements étaient les suivants: T1 (0% RFNP), T2 (antibiotiques), T3 (0,2% RFNP), T4 (0,3% RFNP), T5 (0,4% RFNP) et T6 (0,5% PNLM) répliquée quatre fois à 20 oiseaux par réplication. Les paramètres étudiés étaient une consommation d'aliments, un poids final, un gain de poids, un ratio de conversion d'alimentation, une mortalité et des profilés de sang. Le poids final des poulettes nourris 0,5% RFNP (552.50g) était significativement plus élevé (p <0,05) que celles du régime T1 (0% RFNP) (530 g). Il y avait des différences significatives (p <0,05) dans l'hématologie et les paramètres sériques enregistrés entre les traitements. Volume de la cellule emballé le plus élevé et les concentrations d'hémoglobine de 32% et 10,9 g / 100 ml, respectivement, ont été enregistrées dans T4 (RFNP 0,3%). La valeur la plus élevée (27 µ / L) d'ALT a été enregistrée dans les oiseaux nourris à T6 (régime alimentaire à 0,5% RFNP) et le moins (16µ / L) chez ceux sur T5 (régime avec 0,4% RFNP) et T1 (régime de contrôle). L'inclusion de RFNPa entraîné une meilleure prise de poids chez les oiseaux nourris à T6 (345 g), une consommation moyenne d'alimentation quotidienne moyenne (46,03 g / jour / oiseau) dans T4, rapport de conversion d'alimentation (0,28) en T6 par rapport à T1 (0% RFNP) et ceux traités avec des antibiotiques (T2). Par conséquent, le repas des feuilles de Niruri Phyllanthus peut être considéré comme un alternatif potentiel d'additifs alternatifs pour la production de poulet de couche à la phase du poussin.

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23

Bhate, Dhruv. "Four Questions in Cellular Material Design." Materials 12, no. 7 (2019): 1060. http://dx.doi.org/10.3390/ma12071060.

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The design of cellular materials has recently undergone a paradigm shift, enabled by developments in Additive Manufacturing and design software. No longer do cellular materials have to be limited to traditional shapes such as honeycomb panels or stochastic foams. With this increase in design freedom comes a significant increase in optionality, which can be overwhelming to the designer. This paper aims to provide a framework for thinking about the four key questions in cellular material design: how to select a unit cell, how to vary cell size spatially, what the optimal parameters are, and finally, how best to integrate a cellular material within the structure at large. These questions are posed with the intent of stimulating further research that can address them individually, as well as integrate them in a systematic methodology for cellular material design. Different state-of-the-art solution approaches are also presented in order to provoke further investigation by the reader.

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Rist, Thomas, Róbert Debnár, and Jozef Krišťák. "A Methodology for Cellular Manufacturing Design." Communications - Scientific letters of the University of Zilina 2, no. 1 (2000): 39–44. http://dx.doi.org/10.26552/com.c.2000.1.39-44.

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ISOMURA, Tadashi, Tetsuya TOYODA, and Eisuke KITA. "Structural Design Method Using Cellular Automaton." Proceedings of the JSME annual meeting 2000.1 (2000): 147–48. http://dx.doi.org/10.1299/jsmemecjo.2000.1.0_147.

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RIBEIRO, J. F. FERREIRA, and B. PRADIN. "A methodology for cellular manufacturing design." International Journal of Production Research 31, no. 1 (1993): 235–50. http://dx.doi.org/10.1080/00207549308956723.

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Li, Gang, and Yuan Yao. "Manufacturable Gradient-Variable Cellular Structures Design." IOP Conference Series: Materials Science and Engineering 692 (November 27, 2019): 012010. http://dx.doi.org/10.1088/1757-899x/692/1/012010.

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Seiler, G., A. J. Schuler, and J. A. Nossek. "Design of robust cellular neural networks." IEEE Transactions on Circuits and Systems I: Fundamental Theory and Applications 40, no. 5 (1993): 358–64. http://dx.doi.org/10.1109/81.232580.

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29

Kataoka, Kazunori. "Molecular Design of Cellular Specific Polymers." Kobunshi 41, no. 10 (1992): 706–9. http://dx.doi.org/10.1295/kobunshi.41.706.

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30

Schlueter, Arno, and Tobias Bonwetsch. "Design Rationalization of Irregular Cellular Structures." International Journal of Architectural Computing 6, no. 2 (2008): 197–211. http://dx.doi.org/10.1260/147807708785850104.

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31

Shayan, Ebrahim. "Cellular design for injection moulding shop." Computers & Industrial Engineering 35, no. 3-4 (1998): 487–90. http://dx.doi.org/10.1016/s0360-8352(98)00140-5.

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32

ISHIDA, Ryohei, and Megumi SHIRAGAMI. "406 Topological Design by Cellular Automaton." Proceedings of Ibaraki District Conference 2000 (2000): 101–2. http://dx.doi.org/10.1299/jsmeibaraki.2000.101.

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33

Daikoku, K., and H. Ohdate. "Optimal design for cellular mobile systems." IEEE Transactions on Vehicular Technology 34, no. 1 (1985): 3–12. http://dx.doi.org/10.1109/t-vt.1985.24028.

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34

Lubke, Gabriela Pereira, Élcio Cassimiro Alves, and Macksuel Soares de Azevedo. "Optimized design of cellular steel beams." Revista de Estrutura do Aço 6, no. 1 (2017): 1. http://dx.doi.org/10.17648/aco-2238-9377-6-1-1.

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35

KIM, K. "Quantum-Dot Cellular Automata Design Guideline." IEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences E89-A, no. 6 (2006): 1607–14. http://dx.doi.org/10.1093/ietfec/e89-a.6.1607.

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36

Tang, Yunlong, and Yaoyao Fiona Zhao. "Multifunctional design of heterogeneous cellular structures." Structural and Multidisciplinary Optimization 58, no. 3 (2018): 1121–38. http://dx.doi.org/10.1007/s00158-018-1956-9.

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37

Seepersad, Carolyn C., Rajesh S. Kumar, Janet K. Allen, Farrokh Mistree, and David L. Mcdowell. "Multifunctional design of prismatic cellular materials." Journal of Computer-Aided Materials Design 11, no. 2-3 (2004): 163–81. http://dx.doi.org/10.1007/s10820-005-3167-0.

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38

Mak, K. L., and Y. S. Wong. "Genetic design of cellular manufacturing systems." Human Factors and Ergonomics in Manufacturing 10, no. 2 (2000): 177–92. http://dx.doi.org/10.1002/(sici)1520-6564(200021)10:2<177::aid-hfm4>3.0.co;2-a.

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39

Nakai, Koji, and Akio Ushida. "Design technique of cellular neural network." Electronics and Communications in Japan (Part III: Fundamental Electronic Science) 78, no. 3 (1995): 97–107. http://dx.doi.org/10.1002/ecjc.4430780309.

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40

Yang, Li. "Experimental-assisted design development for an octahedral cellular structure using additive manufacturing." Rapid Prototyping Journal 21, no. 2 (2015): 168–76. http://dx.doi.org/10.1108/rpj-12-2014-0178.

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Purpose – This paper aims to demonstrate the design and verification of a 3D reticulate octahedral cellular structure using both analytical modeling and additive manufacturing. Traditionally, it has been difficult to develop and verify designs for 3D cellular structures due to their design complexity. Design/methodology/approach – Unit cell modeling approach was used to model the octahedral cellular structure. By applying structural symmetry simplification, the cellular structure was simplified into a representative geometry that could be further designed with a standard beam theory. The verification samples were fabricated with EBM process using Ti6Al4V as materials, and compressive testing were performed to evaluate their properties. In addition, designs with different number of unit cells were investigated to evaluate their size effect. Findings – Explicit mechanical property design (including modulus and compressive strength) of the octahedral cellular structure was realized via parametric equations driven by geometrical designs and material types. In addition, it was verified both numerically and experimentally that the octahedral cellular structure exhibit unusual size effect, which is highly predictable. Unlike some of the other cellular structures, the octahedral cellular structure exhibits softening behavior when the number of unit cell increases between the sandwich skins, which could be explained by the upsetting effect commonly observed in bulk deformation processes. Originality/value – This paper established a more comprehensive understanding in the design of octahedral cellular structures, which could enable this type of structure to be designed for sandwich structures with higher fidelity. Therefore, this study not only demonstrated an efficient methodology to design 3D cellular structures using additive manufacturing, but also facilitated the development of design for an additive manufacturing theory.

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41

Ranjbar, Roohallah, Seyed Ahmad Shayannia, Mehdi Amir Miandargh, and Mohammad Reza Lotfi. "Integrated Design of Cellular Production System Using Branch and Bound Algorithm." Discrete Dynamics in Nature and Society 2022 (July 12, 2022): 1–10. http://dx.doi.org/10.1155/2022/9652547.

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Most research done on the design of cellular production systems also has examined one of the main areas of design including cell formation, cellular layout, and material handling. Some research studies also have been done by considering the lack of independence of these areas, two areas simultaneously, and three areas sequentially. The main goal of this research is to present a mathematical framework for designing and also providing the efficient methods for solving the desired problem. Therefore, the main contribution of this paper is to determine the same component according to the characteristics of designs and production requirements. For this purpose, an overall design of a cellular production system or material handling system with cellular layout is examined. Then, the mathematical formulation is presented for the problem and then an efficient solution is presented for the problem. In the provided model, the interaction effects between designs fields are provided. A branch and bound algorithm is also provided to solve this problem. The performance of the provided algorithm and the performance of the provided approach are investigated by using different numerical samples. The results show the performance of the provided algorithm and approach in the design of cellular production systems.

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42

Deng, Feifei, Guangjun Xie, Shaowei Wang, Xin Cheng, and Yongqiang Zhang. "An Ultra-Low-Power Five-Input Majority Gate in Quantum-Dot Cellular Automata." Journal of Circuits, Systems and Computers 29, no. 11 (2020): 2050176. http://dx.doi.org/10.1142/s0218126620501765.

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Quantum-dot cellular automata (QCA) is a highly attractive alternative to CMOS for future digital circuit design, relying on its high-performance and low-power-consumption features. This paper analyzes and compares previously published five-input majority gates. These designs do not perform well in terms of physical properties, especially concerting power consumption. Therefore, an ultra-low-power five-input majority gate in one layer is proposed, which uses a minimum number of cells and smaller area, and achieves the expected highly polarized output compared with previous designs. In order to evaluate its practicability, a new one-bit coplanar full-adder is proposed. The analysis results show that this full-adder performs well compared with existing multilayer and single-layer designs. The number of cells of the proposed design is reduced by 7.14% to get the same area and clock delay compared with the best coplanar full-adder. In addition, its power dissipation is also reduced by 9.28% at 0.5[Formula: see text], 11.09% at 1[Formula: see text] and 12.66% at 1.5[Formula: see text] in terms of average energy dissipation compared with the best single-layer design. QCADesigner tool is used to verify the simulation results of the proposed designs and QCAPro tool is used to evaluate the power dissipation of all considered designs.

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Sen, Bibhash, Ayush Rajoria, and Biplab K. Sikdar. "Design of Efficient Full Adder in Quantum-Dot Cellular Automata." Scientific World Journal 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/250802.

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Further downscaling of CMOS technology becomes challenging as it faces limitation of feature size reduction. Quantum-dot cellular automata (QCA), a potential alternative to CMOS, promises efficient digital design at nanoscale. Investigations on the reduction of QCA primitives (majority gates and inverters) for various adders are limited, and very few designs exist for reference. As a result, design of adders under QCA framework is gaining its importance in recent research. This work targets developing multi-layered full adder architecture in QCA framework based on five-input majority gate proposed here. A minimum clock zone (2 clock) with high compaction (0.01 μm2) for a full adder around QCA is achieved. Further, the usefulness of such design is established with the synthesis of high-level logic. Experimental results illustrate the significant improvements in design level in terms of circuit area, cell count, and clock compared to that of conventional design approaches.

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44

Cheng, Lin, Pu Zhang, Emre Biyikli, Jiaxi Bai, Joshua Robbins, and Albert To. "Efficient design optimization of variable-density cellular structures for additive manufacturing: theory and experimental validation." Rapid Prototyping Journal 23, no. 4 (2017): 660–77. http://dx.doi.org/10.1108/rpj-04-2016-0069.

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Purpose The purpose of the paper is to propose a homogenization-based topology optimization method to optimize the design of variable-density cellular structure, in order to achieve lightweight design and overcome some of the manufacturability issues in additive manufacturing. Design/methodology/approach First, homogenization is performed to capture the effective mechanical properties of cellular structures through the scaling law as a function their relative density. Second, the scaling law is used directly in the topology optimization algorithm to compute the optimal density distribution for the part being optimized. Third, a new technique is presented to reconstruct the computer-aided design (CAD) model of the optimal variable-density cellular structure. The proposed method is validated by comparing the results obtained through homogenized model, full-scale simulation and experimentally testing the optimized parts after being additive manufactured. Findings The test examples demonstrate that the homogenization-based method is efficient, accurate and is able to produce manufacturable designs. Originality/value The optimized designs in our examples also show significant increase in stiffness and strength when compared to the original designs with identical overall weight.

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45

Opgenoord, Max M. J., and Karen E. Willcox. "Design for additive manufacturing: cellular structures in early-stage aerospace design." Structural and Multidisciplinary Optimization 60, no. 2 (2019): 411–28. http://dx.doi.org/10.1007/s00158-019-02305-8.

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46

Khan, Angshuman, and Rohit Shaw. "Design of Multilayered XOR Gate Using Quantum Dot Cellular Automata." Jordan Journal of Electrical Engineering 11, no. 1 (2025): 1. http://dx.doi.org/10.5455/jjee.204-1716825685.

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The rapid advancement of microelectronics technology necessitates the development of high-speed, low-power devices. Quantum Cellular Automaton (QCA) is emerging as a promising technology enabling logic circuits with exceptional operating speeds. The XOR gate is crucial in nanocomputing applications, such as nano-processors and nano-communication units, and requires innovative design approaches. This paper presents a novel design of an XOR gate using a multilayered layout methodology within the QCA framework. The circuit’s design and validation are performed using QCADesigner 2.0.3, while energy dissipation analysis is conducted with QCADesigner-E, resulting in an energy dissipation of 15 meV. Comprehensive parameter analysis, including cost functions, highlights the superiority of the proposed design. A comparative analysis with similar existing multilayered designs shows a 55% improvement in QCA-specific quantum cost. Notably, the proposed design eliminates the need for internal nodes within the layout, enhancing the methodology’s applicability to higher-order and more complex circuits.

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47

Yang, Li, Ola A. Harrysson, Harvey A. West II, Denis R. Cormier, Chun Park, and Kara Peters. "Low-energy drop weight performance of cellular sandwich panels." Rapid Prototyping Journal 21, no. 4 (2015): 433–42. http://dx.doi.org/10.1108/rpj-08-2013-0083.

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Purpose – The aim of this study is to perform a comparative study on sandwich structures with several types of three-dimensional (3D) reticulate cellular structural core designs for their low-energy impact absorption abilities using powder bed additive manufacturing methods. 3D reticulate cellular structures possess promising potentials in various applications with sandwich structure designs. One of the properties critical to the sandwich structures in applications, such as aerospace and automobile components, is the low-energy impact performance. Design/methodology/approach – Sandwich samples of various designs, including re-entrant auxetic, rhombic, hexagonal and octahedral, were designed and fabricated via selective laser sintering (SLS) process using nylon 12 as material. Low-energy drop weight test was performed to evaluate the energy absorption of various designs. Tensile coupons were also produced using the same process to provide baseline material properties. The manufacturing issues such as geometrical accuracy and anisotropy effect as well as their effects on the performance of the structures were discussed. Findings – In general, 3D reticulate cellular structures made by SLS process exhibit significantly different characteristics under low-energy drop weight impact compared to the regular extruded honeycomb sandwich panels. A hexagonal sandwich panel exhibits the largest compliance with the smallest energy absorption ability, and an octahedral sandwich panel exhibits high stiffness as well as good impact protection ability. Through a proper geometrical design, the re-entrant auxetic sandwich panels could achieve a combination of high energy absorption and low response force, making it especially attractive for low-impact protection applications. Originality/value – There has been little work on the comparative study of the energy absorption of various 3D reticulate cellular structures to date. This work demonstrates the potential of 3D reticulate cellular structures as sandwich cores for different purposes. This work also demonstrates the possibility of controlling the performance of this type of sandwich structures via geometrical and process design of the cellular cores with powder bed additive manufacturing systems.

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Almatrood, Amjad F., and Harpreet Singh. "Design of Generalized Pipeline Cellular Array in Quantum-Dot Cellular Automata." IEEE Computer Architecture Letters 17, no. 1 (2018): 29–32. http://dx.doi.org/10.1109/lca.2017.2719021.

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TANAKA, Hideyuki, Yoshinobu KAWAHARA, Takehisa YAIRI, and Kazuo MACHIDA. "Design of Cellular Satellites for Reconfigurable Space System Using Orbital Servicing Robots(Hyper Performance Robotics and Mechatronics,Session: TA1-B)." Abstracts of the international conference on advanced mechatronics : toward evolutionary fusion of IT and mechatronics : ICAM 2004.4 (2004): 41. http://dx.doi.org/10.1299/jsmeicam.2004.4.41_1.

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Medjmedj, Ayoub, Albert Ngalle-Loth, Rudy Clemençon, Josef Hamacek, Chantal Pichon, and Federico Perche. "In Cellulo and In Vivo Comparison of Cholesterol, Beta-Sitosterol and Dioleylphosphatidylethanolamine for Lipid Nanoparticle Formulation of mRNA." Nanomaterials 12, no. 14 (2022): 2446. http://dx.doi.org/10.3390/nano12142446.

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Lipid Nanoparticles (LNPs) are a leading class of mRNA delivery systems. LNPs are made of an ionizable lipid, a polyethyleneglycol (PEG)-lipid conjugate and helper lipids. The success of LNPs is due to proprietary ionizable lipids and appropriate helper lipids. Using a benchmark lipid (D-Lin-MC3) we compared the ability of three helper lipids to transfect dendritic cells in cellulo and in vivo. Studies revealed that the choice of helper lipid does not influence the transfection efficiency of immortalized cells but, LNPs prepared with DOPE (dioleylphosphatidylethanolamine) and β-sitosterol were more efficient for mRNA transfection in murine dendritic cells than LNPs containing DSPC (distearoylphosphatidylcholine). This higher potency of DOPE and β-sitosterol LNPs for mRNA expression was also evident in vivo but only at low mRNA doses. Overall, these data provide valuable insight for the design of novel mRNA LNP vaccines.

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