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Bayrakçeken, Hüseyin, Faruk Emre Aysal, and İbrahim Mutlu. "The Design and Manufacturing of Brake‐Suspension Test Device." Afyon Kocatepe University Journal of Sciences and Engineering 16, no. 2 (June 1, 2016): 454–60. http://dx.doi.org/10.5578/fmbd.27861.
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Alavi, Omid, Leander Van Cappellen, Ward De Ceuninck, and Michaël Daenen. "Practical Challenges of High-Power IGBT’s I-V Curve Measurement and Its Importance in Reliability Analysis." Electronics 10, no. 17 (August 29, 2021): 2095. http://dx.doi.org/10.3390/electronics10172095.
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This paper examines the practical challenges of simplified setups aimed at achieving high-power IGBTs’ IC–VCE curve. The slope of this I–V curve (which is defined as on-resistance RCE) and the point where the VCE–VGE curve visibly bends (threshold gate voltage) can be suitable failure precursor parameters to determine an IGBT’s health condition. A simplified/affordable design for these specific measurements can be used for in-situ condition monitoring or field testing of switching devices. First, the possible I–V curve measurement methods are discussed in detail in order to prevent self-heating. The selected design includes two IGBTs in which the high-side IGBT was the device under test (DUT) with a constant gate voltage (VGE) of 15 V. Then, the low-side IGBT was switched by a short pulse (50 μs) to impose a high-current pulse on the DUT. The VCE–VGE curve was also extracted as an important failure-precursor indicator. In the next stage, a power-cycling test was performed, and the impact of degradation on the IGBT was analyzed by these measurement methods. The results show that after 18,000 thermal cycles, a visible shift in I–V curve can be seen. The internal resistance increased by 13%, while the initial collector-emitter voltage and voltage at the knee point in the VCE–VGE curve slightly changed. It is likely that in our case, during the performed power-cycling test and aging process, the bond wires were most affected, but this hypothesis needs further investigation.
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Olson, John D., Mark T. Cunningham, Russell A. Higgins, Charles S. Eby, and John T. Brandt. "D-dimer: Simple Test, Tough Problems." Archives of Pathology & Laboratory Medicine 137, no. 8 (August 1, 2013): 1030–38. http://dx.doi.org/10.5858/arpa.2012-0296-cp.
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Context.—D-dimer is widely used for exclusion, or as an aid in diagnosis, of venous thromboembolism (VTE); however, the D-dimer assay methods available from manufacturers and the laboratory application of those methods vary widely. Objectives.—To describe the current laboratory practice regarding the assay and reporting of D-dimer. Design.—Laboratories' D-dimer proficiency testing data were analyzed and laboratory practices regarding the performance and reporting of D-dimer were surveyed. Results.—Initial grading of D-dimer proficiency testing demonstrated high variability within and among methods. This variability continued to be present for several years after attempts to intervene. The number of laboratories using D-dimer to exclude VTE grew from 1500 in 2004 to more than 3500 in 2012. Survey and proficiency testing data demonstrated that 33% of laboratories changed the type or magnitude of units from that recommended by the manufacturer, a practice associated with as much as a 20-fold increase in the failure of proficiency testing. Many laboratories used a threshold for the exclusion of VTE that is higher than that recommended by the manufacturer. Many laboratories continue to use qualitative assays with insufficient sensitivity for exclusion of VTE. Conclusions.—There is considerable variability both within and among quantitative methods used to assay D-dimer by laboratories. Laboratory practice continues to vary widely regarding the type and magnitude of units reported and the setting of the threshold for the exclusion of VTE. Although improved, the variability continues despite initial efforts to intervene.
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Li, Xu, Li Min Chang, Li Jing Zhang, and Yan Bin Shi. "Design of Integrated Control and Support Platform for Airborne Digital Image Transmission System." Applied Mechanics and Materials 380-384 (August 2013): 2845–49. http://dx.doi.org/10.4028/www.scientific.net/amm.380-384.2845.
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Aiming at the problems of guarantee equipment deficiency and poor versatility in airborne digital image transmission system, and adopting ATE design ideas, this paper presents a design scheme of integrated control and support platform based on VME bus architecture. With the technology of software radio and software function modules, the design realizes the universal support of multi-type digital image transmission system. Adopting the technology of virtual system, software designs which are hierarchical, modular and interface, it realizes the integrated control of test system. The practice has proved that this support platform has the advantage of stable operation, good versatility, strong practicality and broad application prospects.
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Almheiri, Zayed, Rawan Aleid, and Sharul Sham Dol. "Design of Fixed-Wing and Multi-Copter Hybrid Drone System for Human Body Temperature Measurement during COVID-19 Pandemic." WSEAS TRANSACTIONS ON SYSTEMS 20 (March 16, 2021): 31–39. http://dx.doi.org/10.37394/23202.2021.20.5.
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The purpose of this research is to conduct aerodynamics study and design a hybrid drone system of fixed-wing and multi-copter. The mission of this drone is to measure human body temperature during COVID19 pandemic. The specific aim of the drone is to fly and cover larger industrial areas roughly about 50 km2 with longer flying time than the conventional drone, of about 1.5 hours. The applications of the simulation software such as XFLR5 and ANSYS have a big impact in identifying areas that need to be improved for the drone system. XFLR5 software was used to compare the characteristics of different airfoils with highest lift over drag, L/D ratio. Based on the airfoil selection, it was found that NACA 4412 airfoil produces the highest L/D ratio. The detailed geometry of the drone system includes a fuselage length of 1.9 meters and wingspan of 2 meters. Moreover, 10 sheets of solar panels were placed along the wing for sustainable flight operation to cover wider areas of mission. The structural analysis was done on ANSYS to test the elastic stress, equivalent strain, deformation, factor of safety pressure as well as lift and drag forces under various operational conditions and payloads. The landing gear was analyzed for harsh landing. ANSYS Computational Fluid Dynamics (CFD) was utilized to study the aerodynamics of the drone at different parameters such as the velocities and angles of attack during the operation. This design ensures the stability of the drone during the temperature measurement phase. The best thermal-imaging camera for such purpose would be the Vue Pro R 336, 45° radiometric drone thermal camera with a resolution of 640 x 512 pixels. This camera has the advantage of a permanent continuous out focus that give the ability of taking measurements even if there was changing on the altitude or any kind of vibrations.
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Kim, Soobin, Jessie Klugman, Sarah Norell, Alexandra Kenefake, Laurel Komos, Divya Jain, Moire Corcoran, et al. "Improving VTE prophylaxis adherence among hospitalized adolescents using Human-Centered Design." Journal of Patient Safety and Risk Management 26, no. 4 (July 2021): 172–78. http://dx.doi.org/10.1177/25160435211036784.
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Background/problem statement Venous thromboembolism (VTE) is the leading cause of preventable hospital mortality in the United States; however, compliance with VTE prophylaxis is poor. Most materials for education about VTE prophylaxis are oriented toward adults rather than adolescents, for whom VTE risks are lower and prophylaxis indications differ. We hypothesized that educational materials for adolescents could improve compliance with VTE prophylaxis, reduce nurse burden for initiating and maintaining VTE prevention practices, and reduce practice variation by standardizing the conversation between clinicians and patients. Methods A multidisciplinary team including physicians, nurses, quality experts, communication designers, service designers, and medical students applied a human-centered design (HCD) process to define, iteratively prototype, and test education tools for nurses assigned to adolescents. We piloted a suite of six educational tools for adolescent VTE prophylaxis to fit into the existing hospital workflow. Results An in-room poster was selected after 85% of nurses responded favorably to this intervention. Adolescent adherence with Intermittent Pneumatic Compression Device increased from 69% to 79%, attaining the benchmark goal of 78%. Staff reported greater confidence in educating adolescent patients after the intervention: 62% of nurses and 72% of residents. Conclusion An HCD process helped nurses improve VTE prophylaxis for adolescents with an in-room poster and messaging strategy. Engaging staff in the design increased receptivity and adoption. The piloted materials also helped to create an environment of shared priority among the clinicians.
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Daniyanti, Selly Nur, Anna Fitri Hindriana, and Sri Redjeki. "Implementasi Praktikum Berbasis Diagram Vee Untuk Memunculkan Kemampuan Metakognitif Dan Penguasaan Konsep Siswa." Edubiologica Jurnal Penelitian Ilmu dan Pendidikan Biologi 6, no. 1 (December 28, 2019): 44. http://dx.doi.org/10.25134/edubiologica.v6i1.2362.
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The aim of the research is to determine the implementation of lab activities based Vee diagram to bring out students metacognitive skill and increasing students' learning achievement to the excretory system. Quasi-experimental research with nonequivalent control group design was conducted to the classes. Lab activities based Vee diagram was implemented to the experimental class and lab activities based guided inquiry was implemented to the control class. The sample was determined by purposive sampling technique. Data of the research was obtained from student� worksheet that applying metacognitive strategies and the result of� pre test and post test. Metacognitive skills of experimental class is higher than the control class. Based on analysis, metacognitive skills of experimental class was 75.0 and metacognitive skill of control class was 67.8. Learning achievement of experimental class is higher than control class. The results of the test showed an increasing (N gain) of learning achievement experimental class was 0.53 and control class was 0.41. T test showed t count > t table, which means that there are significant differences between pre-test and post test. Correlation test results showed the corellation between metacognitive skills and learning achievement is very high at 96.7%Keywords: Vee diagram; Guided inquiry; Metacognitive skill; Learning achievement
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Tin, Tan Geok, Noor Azean Atan, Mohd Nihra Haruzuan Mohamad Said, Mohd Fazli Ali, Sanitah Mohd, and Mohd Zolkifli Abd Hamid. "Integrating Animations in Chinese Character Writing Based on Cognitive Theory of Multimedia Learning to Promote Students’ Writing Skills." International Journal of Interactive Mobile Technologies (iJIM) 12, no. 7 (November 8, 2018): 97. http://dx.doi.org/10.3991/ijim.v12i7.9671.
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<p class="0abstract">The complexity of Chinese character caused students facing learning difficulty in mastering the Chinese character writing skills. This study aimed to investigate the effect and students' perception on the implementation of animation in teaching and learning of Chinese character writing based on Cognitive Theory of Multimedia Learning (AniCC Online Learning) via Frog VLE platform. Meanwhile, the relationship of implementation of AniCC Online Learning and pupil's writing performance was also studied to have further insights into the Chinese character teaching and learning situation. Pre-experimental one group pre-test and post-test design were adopted and thirty three Year 1 students were selected as the respondents in this research which involved four types of instruments. There was a significant different (p = 0.013) between the scores of pre-test and post-test for students' writing performance after performing paired samples t-test. The study also showed an increase in the means scores of students' writing skills and an increase in the percentage of students' writing skills ranking at rank 4 or above although no significant different (p = 0.180) was observed between the pre writing assessment and post writing assessment after Wilcoxon Test was performed. The students overall showed high acceptance towards integration of AniCC Online Learning with overall mean score 0.90 (maximum = 1). In sum, the design of AniCC Online Learning via Frog VLE platform is able to improve writing performance as well as to help students in their writing skills.</p>
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Suryani, Irma, and Riski Muliyani. "Penerapan Model Pembelajaran Heuristic Vee terhadap Peningkatan Pemahaman Konsep Siswa Pada Materi Fluida Statis." Journal of Natural Science and Integration 2, no. 2 (October 28, 2019): 52. http://dx.doi.org/10.24014/jnsi.v2i2.7885.
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Penelitian ini bertujuan untuk mendapatkan gambaran mengenai peningkatan aspek pemahaman konsep siswa setelah diterapkan model pembelajaran heuristic vee pada materi fluida statis. Penelitian yang digunakan adalah penelitian kuantitatif, dengan metode weak experiment design dengan desain one group pretest-posttest design. Teknik pengumpulan data yang digunakan adalah tes dan non tes. Instrumen tes berupa soal pre-test dan post-test pemahaman konsep. Sedangkan non tes berupa lembar observasi keterlaksanaan model dan lembar respon siswa. Sampel yang diambil dalam penelitian ini berupa Cluster sampling yang dipilih satu kelas dari seluruh siswa kelas VIII. Populasi dalam penelitian ini adalah kelas VIII SMP Negeri 8 Singkawang dengan jumlah 32 siswa. Hasil penelitian menunjukkan bahwa model pembelajaran heuristic vee dapat meningkatkan pemahaman konsep siswa pada aspek menafsirkan sebesar 0,7 dengan ketegori tinggi, aspek mengklasifikasikan sebesar 0,3 dengan ketegori sedang, aspek menyimpulkan sebesar 0,6 dengan ketegori sedang, ; aspek membandingkan dengan ketegori sedang dan aspek menjelaskan sebesar 0,2 dengan ketegori rendah.
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Robinson, Reagan N., and Anthony N. Taneh. "DIGITAL ILLITERACY: A CONSTRAINT TO TECHNOLOGY EDUCATION ADVANCEMENT IN SOUTH-SOUTH REGION OF NIGERIA." International Journal of Research -GRANTHAALAYAH 6, no. 11 (November 30, 2018): 307–14. http://dx.doi.org/10.29121/granthaalayah.v6.i11.2018.1132.
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Technology education is one the programmes designed to provide technical knowledge and skills necessary for economic development in Nigeria. But technology education programme has a constraint to its advancement which this study investigated. The study adopted the survey research method for the design. The population of the study was 453 persons comprised of 379 students and 74 technical teachers from one Technical College and a University with technology education department in each of the 6 states of the South-South geo-political zone. A simple random sampling technique was used to obtain a sample size of 188 which comprised of 33 technical teachers and 155 students. A 5-item questionnaire was used as the instrument for the study. The questionnaire item was followed by a single response category based on a 5-point rating scale format of Very High Extent (VHE), High Extent (HE), Moderate Extent (ME), Low Extent (LE) and Very Low Extent (VLE). A test re-test method was adapted to test the reliability of the instrument to obtain a coefficient of 0.73. The data gathered was analyzed using mean and z-test analysis to answer the research question and hypothesis respectively. The finding revealed that digital illiteracy is a constraint to technology education advancement in Nigeria. Based on the findings, it was recommended that in order to enhance digital proficiency in technology education, government should adequately provide digital facilities in all technology education institutions in Nigeria.
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Wahidah, Nur Sopiah, Bambang Supriatno, and Mimin Nurjhani Kusumastuti. "Analisis Struktur dan Kemunculan Tingkat Kognitif pada Desain Kegiatan Laboratorium Materi Fotosintesis." Assimilation: Indonesian Journal of Biology Education 1, no. 2 (September 30, 2018): 70. http://dx.doi.org/10.17509/aijbe.v1i2.13050.
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In practical activities usually teachers provide guidance in the form of students’ worksheet or design of laboratory activity. Based on field studies Supriatno (2009), only 24% design laboratory that can be done with the appropriate procedures and complete results in terms of data analysis and conclusion, so it does not support the construction of knowledge. It required the analysis to determine whether design laboratory used already support the construction of knowledge. Design laboratory analysis refers to the Vee diagram and revised Bloom's taxonomy as both lead students to construct knowledge. This research is a descriptive study with purposive sampling technique. The research data captured with a rare test work results table, the table where the component diagram Vee, Vee diagrams scoring table, as well as the revised Bloom's taxonomy table. The results of the 16 samples and 5 samples design laboratory, junior high school design laboratory of photosynthetic material shows that there are still procedural mistakes and instruction unstructured. Vee diagram component analysis results show the general components that arises is the question of focus, the object/event, theories, principles, concepts and knowledge claims. Components that are generally not appear that notes/transformation. Results of the analysis showed scores of each component Vee diagram, Vee diagram on middle and high school degign laboratory generally have not yet reached the ideal score. Results of the analysis showed the emergence of the cognitive level of cognitive level generally required design laboratory in middle and high school, namely C1, C2 and C3, with dominant category procedural C3. This cognitive level is in conformity with the demands of basic competencies middle school, but not in accordance with the demands of basic competencies of high school.
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Robinson, Reagan. "CONSTRAINTS TO REPAIRS AND MAINTENANCE OF ELECTRONIC SYSTEMS IN TECHNICAL COLLEGES’ WORKSHOPS IN RIVERS STATE OF NIGERIA." International Journal of Engineering Technologies and Management Research 5, no. 12 (March 23, 2020): 114–22. http://dx.doi.org/10.29121/ijetmr.v5.i12.2018.333.
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The study investigated constraints to repairs and maintenances of electronic systems in technical colleges’ workshops in Rivers State. The study adopted the survey research design. The population of the study was 342 persons comprised of 309 students and 33 teachers from the five technical colleges in Rivers State. A simple random sampling technique was used to obtain a sample size of 188 which comprises of 33 teachers and 155 students. A 10-item questionnaire was used to collect data. The questionnaire item was followed by a single response category based on a 5-point rating scale format of Very High Extent (VHE), High Extent (HE), Moderate Extent (ME), Low Extent (LE) and Very Low Extent (VLE). A test retest method was adapted to test the reliability of the instrument to obtain a coefficient of 0.65. The data gathered was analyzed using mean and z-test analysis to answer the research questions and hypothesis respectively. The study revealed that absence of technical skills of workshop attendants and motivation of technical instructors are constraints to repairs and maintenances of electronic systems in technical colleges’ workshops in Rivers State. Based on the findings, it was recommended among others that an electronic repairs and maintenance company should be established by government which will enable electronic students to enroll for practical internship quarterly.
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McKenna, Gary, Gavin Baxter, and Thomas Hainey. "Adopting a virtual learning environment towards enhancing students’ self-efficacy." Journal of Applied Research in Higher Education 9, no. 1 (February 6, 2017): 54–69. http://dx.doi.org/10.1108/jarhe-05-2016-0038.
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Purpose The purpose of this paper is to present the results of a semi-experimental study conducted over a period of two years of five degree programmes using a web-based personal tutoring system to enhance learner engagement and students’ self-efficacy, towards using personal development planning (PDP) e-portfolios. Design/methodology/approach The study adopts a semi-experimental approach using quantitative methods utilising a pre- and post-test design in the form of a general self-efficacy questionnaire inventory. Findings The study investigated the extent to which using a virtual learning environment web-based personal tutoring system (VLE WBPTS) can impact positively on the learners’ self-efficacy of the students’ undertaking a degree programme which promotes engagement with PDP e-portfolios. Research limitations/implications More empirical research is required to establish whether PDP and e-portfolios have a positive effect on students’ perceived self-efficacy. Further testing is required to establish whether the VLE WBPTS can have a positive effect on other beneficial elements associated with PDP and e-portfolio usage such as students: learning styles, learner conscientiousness, reflective thinking and effective learner skills. Practical implications The introduction of interventions that involve the utilisation of a VLE WBPTS may have a more significant impact and yield positive results when the period of usage is extended beyond the initial period of six weeks to a minimum period of 12 weeks. Originality/value This study was one of few studies to use a pre/post-test design to collect and analyse empirical data about whether a VLE WBPTS can have a positive effect on students’ self-efficacy towards using PDP e-portfolios.
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Yuan, Yuan, Tianhong Zhang, Zhonglin Lin, Zhiwen Zhao, and Xinglong Zhang. "Actuator Fault Tolerant Control of Variable Cycle Engine Using Sliding Mode Control Scheme." Actuators 10, no. 2 (January 27, 2021): 24. http://dx.doi.org/10.3390/act10020024.
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This paper presents a fault tolerant control (FTC) design for the actuator faults in a variable cycle engine (VCE). Ensured by the multiple variable geometries structure of VCE, the design is realized by distributing the control effort among the unfaulty actuators with the “functional redundancy” idea. The FTC design consists of two parts: the fault reconstruction part and the fault tolerant control part, which use a sliding mode observer (SMO) and a sliding mode control (SMC) scheme respectively. Considering the inaccuracy of the fault reconstruction result, the proposed design requires only inaccurate fault information. The stability of the closed-loop control system is proved and the existence condition for the proposed control law is analyzed. This work also reveals its relation to the sliding mode control allocation design and the adaptive SMC design. An application case is then studied for tolerating the loss of effectiveness fault of the nozzle area actuator. Results show that the FTC design is able to tolerate the fault and achieves the same control goal as in the fault-free situation. Finally, a hardware-in-the-loop test is carried out to verify the design in a real-time distributed control system, which demonstrates its use from the engineering perspective.
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Nurtanto, Muhammad. "Education media development for clutch (EMC) in vocational education: the concept of clutch work." Jurnal Pendidikan Vokasi 8, no. 2 (July 14, 2018): 173. http://dx.doi.org/10.21831/jpv.v8i2.19520.
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This development research aims to describe the working concept of EMC with VPE valuation method. The EMC quality is based on following aspects: (1) valid according to experts; (2) practical according to practitioners; and (e) effective based on students ability test. The developed cycles and procedures refer to the ADDIE model (analysis, design, development, implementation, and evaluation). Data was collected using rating scale sheet (1-5) and percentage of learning using EMC outcomes. The research results show that the valid and practical aspects of the category are valid and practical enough with an average score of 3.68 (73.6%) and 3.75 (75.0%) respectively. While the results of the effective test obtained an average score of 3.74 (74.8%) and the competence test results is 80.51%. The advantages of EMC are attractive design, practical size, and ease of use (user-friendly). Students recommend that they enjoy learning with EMC and it supports learning about chassis.
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Rahmawati, Riska, Rubhan Masykur, and Abi Fadila. "Pengaruh Strategi Pembelajaran Heuristic Vee Terhadap Pemahaman Konsep Matematis Peserta Didik." Desimal: Jurnal Matematika 1, no. 3 (September 15, 2018): 257–64. http://dx.doi.org/10.24042/djm.v1i3.2620.
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The ability to understand the mathematical concepts of learners is important. However, some existing research suggests that understanding of the mathematical concepts of learners is still low. The low understanding of the mathematical concepts of learners is allegedly caused because students are still difficult in solving math problems and less active in the process of learning in class. The implementation of the heuristic vee expenditure strategy is expected to improve the problem. The purpose of this study is to determine the effect of heuristic vee learning strategy on the ability to understand the mathematical concepts of learners. This research type used Quasi-Experiment Design research and sampling technique used is Probability Sampling method with Random Sampling technique. Hypothesis test used in this research is the t-test. The result of statistical test shows that the value of t_hitung based on the calculation obtained t_hitung = 2.096, and t_table = 1.998 so t_hitung>t_table, with a real level of 0.05, in other words, it can be concluded that the students' mathematical concept understanding that expected heuristic vee learning strategy better from the conceptual comprehension ability applied by the lecture method.
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Lazo-Langner, Alejandro, Douglas Coyle, Nicholas J. Barrowman, Tim Ramsay, Philip S. Wells, Dimitrios Scarvelis, Melissa A. Forgie, and Marc Rodger. "Clinical Outcomes in Patients Receiving Venous Thromboembolism (VTE) Prophylaxis after Orthopedic Surgery (OS). A Systematic Review and Meta-Analysis of Proportions." Blood 108, no. 11 (November 16, 2006): 626. http://dx.doi.org/10.1182/blood.v108.11.626.626.
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Abstract Major VTE is the most frequent complication of OS. Current recommendations are to administer prophylaxis with an anticoagulant agent for at least 7–10 days. Numerous studies have evaluated different agents for this purpose. Although the most recent studies are usually methodologically sound, several studies have been hampered by inappropriate designs and insufficient sample sizes. In order to help with the design of future trials we conducted a systematic review of randomized trials evaluating short-term (< 15 days) administration of anticoagulants for VTE prophylaxis in OS and performed a MA of simple proportions to estimate the overall incidence of major VTE (proximal VTE, pulmonary embolism (PE), or death from PE), total VTE (proximal and distal VTE, PE or death from PE), and major bleeding episodes (as defined by the authors and defined using a definition similar to the one proposed by the International Society on Thrombosis and Haemostasis-ISTH). We included randomized trials comparing different drugs for VTE prophylaxis in OS (hip and knee arthroplasty and hip fracture surgery) using systematic evaluation of VTE (ultrasound or venography, pulmonary angiography, tomographic angiography, or ventilation perfusion lung scan). Heterogeneity of proportions was evaluated using a chi ² test and pooled estimates of proportions were obtained using a fixed or a random effects model as appropriate. In the latter the weights were estimated as proposed by Laird and Mosteller. We retrieved 55 studies (135 research arms) which enrolled 42,131 patients. The percentage and variance of major and total VTE and major bleeding are shown in table 1. The total number of events and the number of evaluable patients are shown in table 2. We found differences in the percentage of clinical outcomes associated with the use of different agents for VTE prophylaxis after OS, however, because of the analytical strategy used no estimation of odds or risk reduction can be derived from this data. We believe that these estimates will be of help for the design of future studies.
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Xu, Junjie, Jingbao Gao, Lingxin Kong, Baoqiang Xu, Bin Yang, and Dachun Liu. "Isobaric vapor-liquid equilibria of ternary lead-tin-antimony alloy system at 2 Pa." Journal of Mining and Metallurgy, Section B: Metallurgy, no. 00 (2020): 26. http://dx.doi.org/10.2298/jmmb190529026x.
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In this study, experimental vapor-liquid equilibria data of the ternary Pb-Sn-Sb alloy system are determined using a new experimental method. The experimental VLE data passed the thermodynamic consistency test(Van Ness test), suggesting that the experimental results are reliable. The activities of the components of Pb-Sn-Sb ternary alloy and those of the corresponding three constituent binaries were calculated using the Wilson equation. The predicted values are in good agreement with the data determined from experiments, and the average relative deviation and average standard deviation were smaller than ? 4.00%and ? 0.03for all constituent binaries, respectively, which indicates that the Wilson equation is reliable for calculating the activity of the components of the Pb-Sn-Sb ternary alloy. The VLE data of the Pb-Sn and Sb-Sn binary alloys and Pb-Sn-Sb ternary alloy were calculated based on the VLE theory and Wilson equation. The calculated VLE data were in good agreement with the data determined from experiments, indicating that this method is reliable for calculating the VLE of alloy systems. The proposed study offers a valid method for analyzing the composition of products that are dependent on the distillation temperature and system pressure during vacuum distillation, which is of great significance to the experimental design of this process.
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Prasetyowati, Soekristin. "IMPROVING MOTIVATION AND LEARNING ACHIEVEMENTS WITH VEE DIAGRAM IN SALT HYDROLYSIS MATERIAL AT SENIOR HIGH SCHOOL SUKOMORO." JCER (Journal of Chemistry Education Research) 2, no. 2 (February 21, 2019): 49. http://dx.doi.org/10.26740/jcer.v2n2.p49-57.
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This study aims to describe the use of vee diagrams in an effort to increase motivation and learning achievement in Chemistry class XI.A.1 Sukomoro 1 Senior High School in the material of Salt Hydrolysis. This research is a classroom action research (CAR) which is carried out in two cycles, each cycle consisting of the stages of planning, implementation, observation and reflection. The research is a quasi experiment with a quantitative approach. The research design is Postest-Only Control Design. The object of the study was all students of class XI.IPA.1 of Senior High School Sukomoro in the 2015/2016 school year. Data collection techniques use test methods, and observation methods. The results showed that chemical learning using vee diagrams can increase motivation and learning achievement of Chemistry students in class XI.IPA.1 in Salt Hydrolysis material. In cycle 1 the average cognitive value of 71.05 becomes 80 in cycle 2, learning Chemistry using vee diagrams can be carried out well and can improve student learning motivation especially students gain real experience in everyday life.
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Saarenheimo, Arja, Michael Borgerhoff, Kim Calonius, Anthony Darraba, Alexandre Hamelin, Sara Ghadimi Khasraghy, Amin Karbassi, et al. "Numerical studies on vibration propagation and damping test V1." Rakenteiden Mekaniikka 51, no. 1 (August 16, 2018): 55–80. http://dx.doi.org/10.23998/rm.68954.
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Earthquakes and aircraft impacts induce vibrations that propagate throughout the entire building and they need to be considered in designing SSCs (Structures, Systems and Components). Mainly linear calculation methods have been in use in design practice and the codes and standards consider damping ratios only for linear structural analyses. Induced vibrations, especially in damaged concrete structures, have not been studied extensively enough for optimization of structural frameworks and/or qualified systems and components. Experimental data on damping properties of damaged reinforced concrete are needed also for benchmarking analysis programs and methods.
Recently, within IMPACT project, a new type of test series considering vibration propagation has been carried out at VTT. The test target is a reinforced concrete structure with two parallel walls connected to a floor slab. The front wall is additionally supported by triangular shaped side walls which are connected to the floor slab too. The test structure is supported on elastomeric bearing pads, with back pipes effective mainly in compression and with bars effective in tension. In order to obtain information on vibration propagation in damaged concrete structure at different levels of damage grades the same structure was tested six times. At each time the mass of the deformable stainless steel missile was 50 kg. The hit point located in the middle of the front wall. The impact velocity was about 110 m/s in the first four tests (V1A-D) and about 60 m/s in the remaining two tests (V1E and F). In this paper, numerical results on tests V1A and V1F are compared with the corresponding experimental ones.
The calculated results, such as accelerations, displacements, their response spectra and strains, are compared with experimental measurements. Five finite element (FE) programs are used in computations: Abaqus, Europlexus, LS-DYNA, SOFiSTiK and an in-house code (IHC).
Most of the FE-codes in the present study use shell elements. In Abaqus and SOFiSTiK non-linear behaviour of shell section is modelled by dividing the cross section into layers. Reinforcements are also modelled as layers. In Europlexus and IHC, an alternative approach is adopted in which the non-linear behaviour of concrete and reinforcement is homogenized beforehand in the shell thickness direction obtaining relations between stress resultants and generalized strains valid for the shell section. In LS-DYNA, 3D solid elements for modelling concrete and beam elements for modelling reinforcements are used.
Equations of motion are integrated with explicit central difference time integration method, except in SOFiSTiK implicit integration method is used. Modelling and computations with the mentioned FE-programs are made independently of each other. Computations with LS-DYNA are carried out as blind exercises.
Consideration of the results from benchmarking point of view is still on-going. However it is evident that analysed results follow reasonable well test results in main design parameter level such as maximum displacements, accelerations and strains. Also frequency spectra are estimated reasonably well.
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Patty, Litta Marlin, Jodelin Muninggar, and Nur Aji Wibowo. "PROFILE OF LUNGS VOLUME IN THE DIABETES MELITUS AND NON DIABETES MELITUS." EDU SCIENCES JOURNAL 1, no. 1 (February 18, 2020): 25–36. http://dx.doi.org/10.30598/edusciencesvol1iss1pp25-36.
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International Diabetes Federation states that in 2007 there were 246 million people in the world suffering from diabetes and it is expected to increase to 380 million by 2025. DM can cause susceptibility to infections in the human lung organs due to hyperglycemia. The purpose of this study was to determine the lung volume profile in the form of VT, VCI, VCE and VKP in the DM group and non DM group. This study uses a quantitative descriptive survey design with a sample of 60 people, consisting of 30 people from the DM group and 30 people from the Non DM group. The statistical test used in this study is the Independent statistical sample t-test, the Mann-Whitney test and the Pearson correlation. The results showed: (1) There was a significant difference in the DM of the DM group and the Non DM group with p = 0.021 (p <0.05); (2) There were significant differences in VT, VCI, VCE of the DM group and Non DM group with significant values of VT (p = 0,000 <0.05), VCI (p = 0.003 <0.05) and VCE (p = 0.001 <0.05); (3) There was no significant difference in the VKP of the DM group and the Non DM group with p = 0.805 (p <0.05); (4) Relationship between GD and VT (r = 0.220), GD with VCI (r = 0.308), GD with VCE (r = -0.110), GD with VKP (r = 0.219). So it was concluded that there was a positive relationship between GD and VT, VCI, VKP and also there was a negative relationship between GD and VCE. Suggestion: DM sufferers need to conduct routine checks so that health remains well controlled
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Erdiana, Nira, Usman Kasim, Usman Kasim, Nadia Juwita, and Nadia Juwita. "QAR: Strategy implementation for reading comprehension of recount texts." Studies in English Language and Education 4, no. 2 (September 1, 2017): 247. http://dx.doi.org/10.24815/siele.v4i2.8500.
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The objective of this research is to find out whether QAR strategy is effective in reading comprehension of recount text. This research uses experimental research design. This research took place at Madrasah Tsanawiyah Negeri Model Banda Aceh. A second grade class was chosen as the research sample, which consisted of 36 students. The research instrument used to gather the data was a set of essay tests, which were divided to pre-test and post-test. The result of the research was analyzed by using paired t-test formula. The calculation result shows that the observed t value is less than t lower critical vaue in the t distribution table (-5.624 2.030) at the 0.05 level of significance with 35 degree of freedom. It means that null hypothesis (H0) is rejected, which proves that Question Answer Relationship strategy effectively improves the second grade students’ reading comprehension of recount text.
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Xu, Bing Li, Hui Lin, Wei Ning Cui, Ya Hu, Jun Zhu, and Sammy Tang. "CUGrid and VGE Based Air Pollution Dispersion Simulation." Advanced Materials Research 143-144 (October 2010): 1305–10. http://dx.doi.org/10.4028/www.scientific.net/amr.143-144.1305.
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Air pollution dispersion is a typical geographic process. A reasonable way to simulate air pollution dispersion is to modeling the dispersion and presents the results in a geographically referenced virtual environment. In this research, we apply the concept of virtual geographic environments (VGE), which is coined in the community of geographic information science, to facilitate air pollution dispersion by integrating MM5 and VGE. Because MM5 is computation intensive, the CUGrid is used in this research to decrease the computation time. Our research focuses on three key points, which are the platform design, MM5 integration and computation on CUGrid, and geographical visualization of air pollution dispersion in VGE. Based on the prototype system, a case of simulating air pollution dispersion in Pearl River Delta is employed to validate and test the rationality of the methodology. As shown in this case study, VGE can provide a good way to visualize air pollution dispersion and the CUGrid can decrease model computation time significantly.
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Whiley, Harriet, Thilini Piushani Keerthirathne, Muhammad Atif Nisar, Mae A. F. White, and Kirstin E. Ross. "Viral Filtration Efficiency of Fabric Masks Compared with Surgical and N95 Masks." Pathogens 9, no. 9 (September 17, 2020): 762. http://dx.doi.org/10.3390/pathogens9090762.
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In response to the Coronavirus Disease 2019 (COVID-19) pandemic, current modeling supports the use of masks in community settings to reduce the transmission of SARS-CoV-2. However, concerns have been raised regarding the global shortage of medical grade masks and the limited evidence on the efficacy of fabric masks. This study used a standard mask testing method (ASTM F2101-14) and a model virus (bacteriophage MS2) to test the viral filtration efficiency (VFE) of fabric masks compared with commercially available disposable, surgical, and N95 masks. Five different types of fabric masks were purchased from the ecommerce website Etsy to represent a range of different fabric mask designs and materials currently available. One mask included a pocket for a filter; which was tested without a filter, with a dried baby wipe, and a section of a vacuum cleaner bag. A sixth fabric mask was also made according to the Victorian Department of Health and Human Services (DHHS) guidelines (Australia). Three masks of each type were tested. This study found that all the fabric masks had a VFE of at least 50% when tested against aerosols with an average size of 6.0 µm (VFE(6.0 µm)). The minimum VFE of fabric masks improved (to 63%) when the larger aerosols were excluded to give and average aerosol size of 2.6 µm (VFE(2.6 µm)), which better represents inhaled aerosols that can reach the lower respiratory system. The best performing fabric masks were the cotton mask with a section of vacuum cleaner bag (VFE(6.0 µm) = 99.5%, VFE(2.6 µm) = 98.8%) or a dried baby wipe (VFE(6.0 µm) = 98.5%, VFE(2.6 µm) = 97.6%) in the pocket designed for a disposable filter, the mask made using the Victorian DHHS design (VFE(6.0 µm) = 98.6%, VFE(2.6 µm) =99.1%) and one made from a layer of 100% hemp, a layer of poly membrane, and a layer of cheesecloth (VFE(6.0 µm) = 93.6%, VFE(2.6 µm) = 89.0%). The VFE of two surgical masks (VFE(6.0 µm) = 99.9% and 99.6%, VFE(2.6 µm) = 99.5% and 98.5%) and a N95 masks (VFE(6.0 µm) = 99.9%, VFE(2.6 µm) = 99.3%) were comparable to their advertised bacterial filtration efficacy. This research supports the use of fabric masks in the community to prevent the spread of SARS-CoV-2; however, future research is needed to explore the optimum design in ensuring proper fit. There is also a need for mass education campaigns to disseminate this information, along with guidelines around the proper usage and washing of fabric masks.
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Le, Xuan Chung, Tuan Anh Le, Viet Cuong Phan, Van Dien Mai, Duc Khue Pham, Thi Hoa Bui, Duy Linh Bui, The Nghia Bui, Ho Phong Vi, and Duc Ton Nguyen. "Building a VME spectrometer and testing Si PIN diode detector: a feasibility study for the first nuclear astrophysical experiments using a pelletron." Nuclear Science and Technology 11, no. 1 (March 15, 2021): 1–8. http://dx.doi.org/10.53747/jnst.v11i1.126.
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This work presents the logical design, connections between NIM and VME electronic modules, and the data acquisition programming to build a complete detector readout system. The test experiments were carried out with commercial silicon PIN diode S3590-09 bare detectors bombarded by charged particles from a 241Am α-source and Rutherford elastic backscattering (RBS) protons induced by 2.5 MeV proton beam bombarding on an Au-on-glass target, and with a NaI scintillation detector bombarded by gammas from 27Al(p, γ)28Si reaction with proton beam energy of 1.379 MeV. The test showed that the spectrometer operated steadily and its versatility for different kind of detector. The energy resolutions of the Si diodes were less than 0.5% energy of a charged particle, which satisfies the foreseen requirement for the upcoming experiments.
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Hamdani, Kiki Kusyaeri, and Yati Haryati. "COMPARISON OF YIELD AMONG DIFFERENT HIGH YIELDING VARIETIES OF WETLAND RICE." Agric 33, no. 1 (August 1, 2021): 57–66. http://dx.doi.org/10.24246/agric.2021.v33.i1.p57-66.
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New superior varieties (VUB) are a reliable technological innovation to increase rice productivity. This study aims to determine the yield potential of some lowland rice VUB. The assessment was carried out on land owned by a member of the Sumber Rejeki Farmer Group, Cintaratu Village, Lakbok District, Ciamis Regency at Dry Season II in June-September 2020. The study used a randomized complete block design (RCBD) with six varieties of treatment and was repeated ten times. The varieties tested were Inpari 32, Inpari 42, Padjadjaran, Cakrabuana, Inpari IR Nutrizinc, and Siliwangi varieties. The variables observed included the growth component, yield component, and yield component. Data were analyzed using the F test followedby the Duncan Multiple Range Test at the Q=5% level. In addition, a correlation test was conducted between the growth components, yield components, and yields. The results of the study indicated that the new superior rice varieties studied had different performance in growth, number of tillers, yield, and yield components. Inpari 42 variety produced the highest productivity, namely 6.88 ton ha-1 which was supported by the number of grains per panicle, percentage of filled grains per panicle, and percentage of empty grain per panicle which were better than other varieties. Plant height and number of grains per panicle were positively correlated with yield.
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Van Wyk, Johann, Theo Bothma, and Marlene Holmner. "A conceptual virtual research environment model for the management of research data, a South African perspective." Library Management 41, no. 6/7 (July 2, 2020): 417–46. http://dx.doi.org/10.1108/lm-02-2020-0037.
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PurposeThe purpose of this article is to give an overview of the development of a Virtual Research Environment (VRE) conceptual model for the management of research data at a South African university.Design/methodology/approachThe research design of this article consists of empirical and non-empirical research. The non-empirical part consists of a critical literature review to synthesise the strengths, weaknesses (limitations) and omissions of identified VRE models as found in literature to develop a conceptual VRE model. As part of the critical literature review concepts were clarified and possible applications of VREs in research lifecycles and research data lifecycles were explored. The empirical part focused on the practical application of this model. This part of the article follows an interpretivist paradigm, and a qualitative research approach, using case studies as inquiry method. Case studies with a positivist perspective were selected through purposive sampling, and inferences were drawn from the sample to design and test a conceptual VRE model, and to investigate the management of research data through a VRE. Investigation was done through a process of participatory action research (PAR) and included semi-structured interviews and participant observation data collection techniques. Evaluation of findings was done through formative and summative evaluation.FindingsThe article presents a VRE conceptual model, with identified generic component layers and components that could potentially be applied and used in different research settings/disciplines. The article also reveals the role that VREs play in the successful management of research data throughout the research lifecycle. Guidelines for setting up a conceptual VRE model are offered.Practical implicationsThis article assisted in clarifying and validating the various components of a conceptual VRE model that could be used in different research settings and disciplines for research data management.Originality/valueThis article confirms/validates generic layers and components that would be needed in a VRE by synthesising these in a conceptual model in the context of a research lifecycle and presents guidelines for setting up a conceptual VRE model.
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Luo, R. K., L. M. Peng, X. P. Wu, and W. J. Mortel. "Load–deflection prediction and stress verification in extreme large deformation of rubber suspensions used in rail vehicles." Proceedings of the Institution of Mechanical Engineers, Part F: Journal of Rail and Rapid Transit 226, no. 2 (August 1, 2011): 228–32. http://dx.doi.org/10.1177/0954409711408008.
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Rubber suspensions are important components in railway vehicles. The offset sandwich mount is a type of rubber spring used on rail vehicles as the primary suspension above the axlebox on a bogie. In this installation, a pair of mounts is arranged within a vee configuration, such that the movements in all planes are controlled by a combined shear and compression displacement. This article evaluates the important aspects in the rubber suspension design when using a higher order material properties in an extreme large deformation. On one hand, using a higher order of material model has enabled prediction of larger deformations that are required for the actual product in the ultimate loading used in rail dynamic environment. On the other hand, using a higher order of material model with full integration elements, however, may mislead the design concept to an incorrect direction. It is important to note that the accuracy of the stress calculation is not guaranteed by a reasonable load–deflection prediction, even validated against a test result. Three methods to check the reliability of the calculated stresses are proposed. The investigation has been validated against a laboratory test. It is suggested that a higher order of material model should be used with reduced integration elements.
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Marpaung, Rini Rita T., Berti Yolida, and Faradilla Riana Putri. "Student’s scientific literacy on environmental pollution material based on SETS learning approach combined with Vee Diagram." JPBI (Jurnal Pendidikan Biologi Indonesia) 7, no. 2 (July 28, 2021): 117–25. http://dx.doi.org/10.22219/jpbi.v7i2.15718.
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The student’s scientific literacy is vital in improving students’ awareness of several issues. This study was intended to describe the effect of the SETS learning approach combined with Vee Diagram on students’ scientific literacy especially on Environmental Pollution Material. This study used a nonequivalent pretest-posttest control group design. The survey involved 60 students who were selected using cluster random sampling technique. The quantitative data, in terms of pretest, posttest, and N-gain scores were analyzed using Independent-sample t-test at the 5% significance level. The results showed that, based in the N-gain scores, the experiment class was classified in moderate category and the control class belonged to low category. This means that the SETS learning approach combined with Vee Diagram influence student’s scientific literacy on Environmental Pollution Material. Therefore, this combination is recommended to be implemented in class to enhance students' scientific literacy skills.
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Fraser, Karl, Nicole C. Roy, Louisa Goumidi, Alexandre Verdu, Pierre Suchon, Felipe Leal-Valentim, David-Alexandre Trégouët, Pierre-Emmanuel Morange, and Jean-Charles Martin. "Plasma Biomarkers and Identification of Resilient Metabolic Disruptions in Patients With Venous Thromboembolism Using a Metabolic Systems Approach." Arteriosclerosis, Thrombosis, and Vascular Biology 40, no. 10 (October 2020): 2527–38. http://dx.doi.org/10.1161/atvbaha.120.314480.
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Objective: Deep vein thrombosis and pulmonary embolism referred as venous thromboembolism (VTE) are a common cause of morbidity and mortality. Plasma from healthy controls or individuals who have experienced a VTE were analyzed using metabolomics to characterize biomarkers and metabolic systems of patients with VTE. Approach and Results: Polar metabolite and lipidomic profiles from plasma collected 3 months after an incident VTE were obtained using liquid chromatography mass spectrometry. Fasting-state plasma samples from 42 patients with VTE and 42 healthy controls were measured. Plasma metabolomic profiling identified 512 metabolites forming 62 biological clusters. Multivariate analysis revealed a panel of 21 metabolites altogether capable of predicting VTE status with an area under the curve of 0.92 ( P =0.00174, selectivity=0.857, sensitivity=0.971). Multiblock systems analysis revealed 25 of the 62 functional biological groups as significantly affected in the VTE group ( P <0.05 to control). Complementary correlation network analysis of the dysregulated functions highlighted a subset of the lipidome composed mainly of n-3 long-chain polyunsaturated fatty acids within the predominant triglycerides as a potential regulator of the post-VTE event biological response, possibly controlling oxidative and inflammatory defence systems, and metabolic disorder associated dysregulations. Of interest was microbiota metabolites including trimethylamine N-oxide that remained associated to post incident VTE patients, highlighting a possible involvement of gut microbiota on VTE risk and relapse. Conclusions: These findings show promise for the elucidation of underlying mechanisms and the design of a diagnostic test to assess the likely efficacy of clinical care in patients with VTE.
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Male, Christoph, Donald L. Yee, Christian Loewe, Rajesh Krishnamurthy, Elizabeth Chalmers, Jane Newburger, Luz-Margarita Ramirez, Ronald Portman, and Lesley G. Mitchell. "Comparison Of Ultrasound Versus Magnetic Resonance Venography For Diagnosis Of Catheter-Related Thrombosis In Children: A Multicenter Multinational Study." Blood 122, no. 21 (November 15, 2013): 2377. http://dx.doi.org/10.1182/blood.v122.21.2377.2377.
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Abstract Background Venous thrombotic events (VTE) in children are related to central venous catheters and occur predominantly in the upper venous system. In routine clinical practice, ultrasound (US) is the most frequently used imaging technique for diagnosis of VTE in children because of its ease of use and non-invasiveness. However, US is known to be relatively insensitive for detection of VTE in the central upper venous system. Magnetic resonance venography (MRV) is a promising alternative as MRV can comprehensively image the central venous system, is minimally invasive and does not involve radiation. However, MRV involves high technical and logistic demands, and requires sedation in young children. Objectives To compare the feasibility and diagnostic accuracy of US and MRV for diagnosis of central venous catheter related VTE in children. Methods Study Design: Cross-sectional diagnostic study. Study population: Children 0-<18 years of age with a central venous catheter in place for any reason were recruited prospectively and consisted of i) children who are asymptomatic for VTE: children who were screened for central venous catheter-related VTE within 20-60 days of catheter placement ii) children who are symptomatic for VTE: children presenting with signs and symptoms of central venous catheter related VTE within 7 days of symptom onset (all study-related imaging tests were completed within this time period). Children were excluded in case of i) systemic anticoagulant or antiplatelet therapy, and ii) inability to undergo contrast MRV. Imaging tests: Each participant had three imaging tests performed i) Doppler compression US ii) MRV without contrast iii) MRV with gadolinium contrast. All imaging studies were performed within 48 hours of each other. Data collection included clinical and demographic information on each subject, imaging and video documentation of each US and MRV. Central Adjudication Committee: All imaging studies were blinded and independently reviewed and interpreted by a central adjudication committee for the presence or absence of VTE. Outcomes: The two main study outcomes were 1) Feasibility of performing each test: assessed by a) the number of children who completed each diagnostic study and b) the number of evaluable studies; and 2) Diagnostic accuracy of each diagnostic test: assessed by the proportion of VTE identified by the respective test in relation to the total number of VTE identified by any imaging modality. Results A total of 152 children were enrolled from 24 centers in 9 countries: Argentina, Brazil, Mexico, United States, Canada, United Kingdom, Netherlands, Austria and Germany. The median age (range) for children was 11 years (2 months to 17 years). Fourteen (9.2%) children had clinical symptoms of VTE. One hundred and thirty three (88%) children had US completed, 113 (74%) had MRV without contrast and 113 (74%) had MRV with contrast. 18 subjects withdrew from the study before any test was performed for various reasons. Adjudication and analysis are ongoing, and will be completed by October 14th, 2013. Therefore, final results regarding the feasibility and diagnostic accuracy of each test will be available at the time of presentation. Conclusion We have completed the largest and most comprehensive study to date comparing the feasibility and diagnostic accuracy of currently available non-invasive imaging modalities for detecting central venous catheter related VTE in children. Ultrasound demonstrated better feasibility than MRV, however, MRV still proved feasible in nearly three-quarters of pediatric subjects and was performed without sedation in individuals as young as 2 months old. The overall feasibility and diagnostic accuracy of each test will be reported after final adjudication and analysis are complete. The study findings will be used to formulate an effective pediatric diagnostic algorithm for diagnosis of central venous catheter-related VTE. The algorithm will be used as guidance for clinical practice as well as outcome assessments for clinical trials of antithrombotic agents in children. Disclosures: Male: Bristol Myer Squibb: Consultancy. Yee:Bristol Myer Squibb: Research Funding. Loewe:Bristol Myer Squibb: Consultancy. Krishnamurthy:Koninklijke Philips NV: Research Funding; Bristol Myer Squibb: Consultancy. Chalmers:Bristol Myer Squibb: Consultancy. Newburger:Merck: Consultancy; Janssen Pharmacutical: Consultancy; Bristol Myer Squibb: Consultancy. Ramirez:Bristol Myer Squibb: Employment. Portman:Bristol Myer Squibb: Employment. Mitchell:Bristol Myer Squibb: Consultancy; Eisai: Consultancy; Boehringer Ingelheim: Consultancy.
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Iftikhar, Sajida, Ayesha Farooq, Muhammad Farooq Latif, SARWAT Ara, Muhammad Salim, Asif Maqbool, and Aatar Iftikhar. "Venous thromboembolism an observational study to assess the risk of venous thromboembolism in surgical patients." Professional Medical Journal 26, no. 09 (September 10, 2019): 1531–36. http://dx.doi.org/10.29309/tpmj/2019.26.09.4018.
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Objectives: The aim of this study is to assess the risk of venous thromboembolism (VTE) in surgical patients. Study Design: An Observational Study. Setting: 4 Tertiary Hospitals in Faisalabad city. Period: 6 months from July 2015 to December 2015. Material & Methods: Clinical data sheets of surgical in patients of 4 teaching hospitals in Faisalabad city were retrospectively reviewed. Caprini assessment model (CAM) was used for VTE risk assessment and the patients were classified into very high risk (VHR), high risk (HR), moderate risk (MR) and low risk (LR) groups. The data was collected on an Excel spread sheet and statistical analysis was done using SPSS version 17. Chi square test was carried out to assess the association of VTE risk with age, gender, BMI and surgical units. Results: We identified a total of 256 patients from July 2015 to December 2015. The median age was 42 years. 118 (46%) patients were male and 138 (54%) were female. 106 (41.4%) patients were VHR and 124 (48.4%) patients were HR for VTE according to CAM. Nineteen (7.4%) patients were MR and only 7 (2.7%) patients were LR. Higher age and male gender were found to be significantly associated with the high risk for VTE (p<0.001). Conclusion: Our study shows that the postoperative surgical patients are at higher risk of developing VTE. There is statistically significant association between increasing age and male gender with risk of VTE in this group of patients.
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Loprinzi, Charles, Aneel Ashrani, Juliana Perez Botero, Roberto Leon Ferre, Stanislav Henkin, Charles Lenz, Jennifer Le-Rademacher, Waldemar Wysokinski, and Robert McBane. "Apixaban and dalteparin in active malignancy associated venous thromboembolism." Thrombosis and Haemostasis 117, no. 10 (2017): 1952–61. http://dx.doi.org/10.1160/th17-03-0193.
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SummaryCurrently, low molecular weight heparin (LMWH) is the guideline endorsed treatment of patients with cancer associated venous thromboembolism (VTE). While apixaban is approved for the treatment of acute VTE, there are limited data supporting its use in cancer patients. The rationale and design of this investigator initiated Phase IV, multicenter, randomized, open label, superiority trial assessing the safety of apixaban versus dalteparin for cancer associated VTE is provided (ADAM-VTE; NCT02585713). The main aim of the ADAM-VTE trial is to test the hypothesis that apixaban is associated with a significantly lower rate of major bleeding compared to dalteparin in the treatment of cancer patients with acute VTE. The primary safety outcome is rate of major bleeding. Secondary efficacy objective is to assess the rates of recurrent VTE or arterial thromboembolism. Cancer patients with acute VTE (n=300) are randomized to receive apixaban (10 mg twice daily for 7 days followed by 5 mg twice daily thereafter) or dalteparin (200 IU/Kg daily for 30 days followed by 150 IU/kg daily thereafter) for 6 months. Stratification factors used for randomization include cancer stage and cancer specific risk of venous thromboembolism using the Khorana score. Participating centers are chosen from the Academic and Community Cancer Research United (ACCRU) consortium comprised of 90 oncology practices in the United States and Canada. Based on the hypothesis to be tested, we anticipate that these trial results will provide evidence supporting apixaban as an effective treatment of cancer associated VTE at lower rates of major bleeding compared to LMWH.
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Eka Astika, Sri Anggraeni, and Bambang Supriatno. "Analisis Komponen Penyusun Desain Kegiatan Laboratorium Enzim Katalase." BIODIK 6, no. 3 (September 11, 2020): 343–56. http://dx.doi.org/10.22437/bio.v6i3.9469.
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The purpose of this study is to : (a) obtain an overview of the compatibility of the practical goals with the Basic Competencies developed in the design of laboratorium activities, (b) obtain an overview of the suitability of the practical goals and proceduaral steps with the concept to be achieved, (c) find out whether the design of laboratory activities used has supported knowledge construction based on an analysis of the componets in the design of laboratory activities. This research uses descriptive qualitative method through the ANCOR stages, namely Analysis, Trial, and Reconstruction of five catalase enzyme material laboratory design. The analysis carried out includes an analysis of the arious activities listed in the worksheet so that it can be seen how much these activities involve students in te science process, their relevance to the applicable curriculum, the relationship between the phenomena revealed and the concepts to be achieved and construct student knowledge. The instrument used is the modification of the instrument to analyze the suitability of pratikum activities with the curriculum and Diagram Vee to see whether the worksheet used constructs knowledge or not. The analysis included conceptual analysis, pratical analysis and knowledge construction analysis on various worksheet catalase enzyme tests. The catalase enzyme test practicum emphasizes students’ mastery of the catalase enzyme test material that is both principle and procedural, where students are required to be able to understand the properties of enzymes, factors that influence the work of enzymes, and the role of enzymes in metabolism. Thus it takes a series of competencies of students’ knowledge, skills and attitudes in mastering the catalase enzyme test material. For this reason, it requires a worksheet design that forms essential concepts so that they can achieve their goals and are in line with the demands of Basic Competence.
Abstrak. Tujuan penelitian ini yaitu untuk: (a) memperoleh gambaran mengenai kesesuaian tujuan pratikum dengan Kompetensi Dasar yang dikembangkan dalam LKS, (b) memperoleh gambaran mengenai kesesuaian tujuan pratikum dengan langkah – langkah prosedural dengan konsep yang akan dicapai, (c) mengetahui apakah LKS yang digunakan sudah menunjang konstruksi pengetahuan berdasarkan analisis komponen-komponen dalam LKS. Penelitian ini merupakan penelitian Analisis Isi (Content Analysis). Analisis yang dilakukan meliputi analisis terhadap ragam kegiatan yang tertera dalam LKS sehingga dapat diketahui seberapa besar kegiatan tersebut melibatkan siswa dalam proses sains, relevansinya dengan kurikulum yang berlaku, hubungan antara fenomena yang diungkap dengan konsep yang akan dicapai dan mengkonstruksi pengetahuan siswa. Instrumen yang digunakan adalah modifikasi instrumen untuk menganalisis kesesuaian kegiatan pratikum dengan kurikulum dan Diagram Vee untuk melihat apakah LKS yang digunakan mengkonstruksi pengetahuan atau tidak. Analisis yang dilakukan meliputi analisis konseptual, analisis pratikal dan analisis konstruksi pengetahuan pada berbagai LKS uji enzim katalase. Pratikum uji enzim katalase menekankan pada penguasaan siswa terhadap materi uji enzim katalase yang bersifat prinsip serta prosedural, dimana siswa dituntut untuk mampu memahami sifat-sifat enzim, faktor-faktor yang mempengaruhi kerja enzim, serta peran enzim didalam metabolisme. Dengan demikian dibutuhkan serangkaian kompetensi pengetahuan, keterampilan, dan sikap siswa dalam menguasai materi uji enzim katalase. Untuk itu dibutuhkan desain LKS yang membentuk konsep – konsep esensial sehingga dapat mencapai tujuan dan sejalan dengan tuntutan Kompetensi Dasar.
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Spyropoulos, Alex, Julie Zrubek, Walter Ageno, Gregory Albers, C. Elliott, Jonathan Halperin, Lloyd Haskell, et al. "The MARINER trial of rivaroxaban after hospital discharge for medical patients at high risk of VTE." Thrombosis and Haemostasis 115, no. 06 (2016): 1240–48. http://dx.doi.org/10.1160/th15-09-0756.
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SummaryHospital-associated venous thromboembolism (VTE) is a leading cause of premature death and disability worldwide. Evidence-based guidelines recommend that anticoagulant thromboprophylaxis be given to hospitalised medical patients at risk of VTE, but suggest against routine use of thromboprophylaxis beyond the hospital stay. The MARINER study is a randomised, double-blind, placebo-controlled trial to evaluate the efficacy and safety of thromboprophylaxis using rivaroxaban, begun at hospital discharge and continued for 45 days, for preventing symptomatic VTE in high-risk medical patients. Eligible patients are identified using the International Medical Prevention Registry on Venous Thromboembolism (IMPROVE VTE) risk score, combined with a laboratory test, D-dimer. The rivaroxaban regimen is 10 mg once daily for patients with CrCl ≥ 50 ml/min, or 7.5 mg once daily for patients with CrCl ≥ 30 ml/min and < 50 ml/ min. The primary efficacy outcome is the composite of symptomatic VTE (lower extremity deep-vein thrombosis and non-fatal pulmonary embolism) and VTE-related death. The principal safety outcome is major bleeding. A blinded clinical events committee adjudicates all suspected outcome events. The sample size is event-driven with an estimated total of 8,000 patients to acquire 161 primary outcome events. Study design features that distinguish MARINER from previous and ongoing thromboprophylaxis trials in medically ill patients are: (i) use of a validated risk assessment model (IMPROVE VTE) and D-dimer determination for identifying eligible patients at high risk of VTE, (ii) randomisation at the time of hospital discharge, (iii) a 45-day treatment period and (iv) restriction of the primary efficacy outcome to symptomatic VTE events.
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Song, Yohan, Jennifer C. Alyono, Noor-E.-Seher Ali, and Nikolas H. Blevins. "Postoperative Venous Thromboembolism after Extracranial Otologic Surgery." Otolaryngology–Head and Neck Surgery 161, no. 1 (March 12, 2019): 144–49. http://dx.doi.org/10.1177/0194599819835743.
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Objective To determine the incidence of postoperative venous thromboembolism (VTE) in adults undergoing otologic surgery. Study Design Cross-sectional retrospective study. Setting Single tertiary academic center. Subjects and Methods Adults undergoing nononcologic, extracranial otologic surgery from August 2009 to December 2016. Patients with postoperative diagnosis VTE codes were identified. Imaging and clinical documents were searched for VTE evidence within the first 30 postoperative days. Methods of thromboprophylaxis were documented, and Caprini risk scores were calculated. Results In total, 1213 otologic surgeries were evaluated. No postoperative VTE events were identified (0/1268). Mean age was 51.0 ± 17.3 years (range, 18.1-93.4 years). Average length of surgery was 136.0 ± 79.0 minutes (range, 5-768 minutes). The average Caprini score in all patients was 4.0 ± 1.7 (range, 1-15). Eighty-five percent of patients had a Caprini score ≥3, the threshold at which chemoprophylaxis has been recommended in general surgery patients by the American College of Chest Physicians 2012 guidelines. Six patients had documented preoperative chemoprophylaxis and a Caprini score of 4.8 ± 1.7. This was not significantly different from that of patients who did not receive preoperative chemoprophylaxis ( t test, P = .3). The literature would estimate a rate of 3.7% VTE in adults with similar Caprini scores undergoing general surgery procedures with no VTE prophylaxis. Conclusion The Caprini risk assessment model may overestimate VTE risk in patients undergoing extracranial otologic surgery. Postoperative VTE following otologic surgery is rare, even in patients traditionally considered moderate or high risk. Chemoprophylaxis guidelines in this group should be balanced against the potential risk of increased intraoperative bleeding and its associated effects on surgical visualization and morbidity.
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Khlaisang, Jintavee, and Kemmanat Mingsiritham. "Engaging Virtual Learning Environment System to Enhance Communication and Collaboration Skills among ASEAN Higher Education Learners." International Journal of Emerging Technologies in Learning (iJET) 11, no. 04 (April 5, 2016): 103. http://dx.doi.org/10.3991/ijet.v11i04.5503.
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The study aims to design and develop a Virtual Learning Environment (VLE) system to enhance the communication and collaboration skills of higher education learners in the ASEAN cultural community. The system was developed based on a literature review of ASEAN to identity its educational goals for 2015, as well as the subjects of open learning, VLE, active learning, activity based learning, ASEAN cultural community, and collaboration and communication skills in 21st century. The results of the literature review were developed into a questionnaire for 400 higher education instructors. The survey results were then tabulated using G* Power and were analyzed using Exploratory Factor Analysis (EFA) to find the core elements to be developed to be an appropriate VLE system. The resulting system was tested using a sample group of 30 volunteer undergraduate students from 5 ASEAN member countries. Data analysis using t-test dependent indicated that there was statistical difference between pre and post self-assessment scores of the 21st century skills in communication and collaboration at a 0.05 level of significance. The result was consistent with the results of behavior and trace observations and the quality of project assignments produced using the system. The system developed consisted of four elements was approved by experts in the education field.
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Schrank, Gregory M., Graham M. Snyder, Roger B. Davis, Westyn Branch-Elliman, and Sharon B. Wright. "The discontinuation of contact precautions for methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus: Impact upon patient adverse events and hospital operations." BMJ Quality & Safety 29, no. 10 (July 18, 2019): 1.1–2. http://dx.doi.org/10.1136/bmjqs-2018-008926.
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BackgroundContact precautions for endemic methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) are a resource-intensive intervention to reduce healthcare-associated infections, potentially impeding patient throughput and limiting bed availability to isolate other contagious pathogens. We investigated the impact of the discontinuation of contact precautions (DcCP) for endemic MRSA and VRE on patient outcomes and operations metrics in an acute care setting.MethodsThis is a retrospective, quasi-experimental analysis of the 12 months before and after DcCP for MRSA and VRE at an academic medical centre. The frequency for bed closures due to contact isolation was measured, and personal protective equipment (PPE) expenditures and patient satisfaction survey results were compared using the Wilcoxon signed-rank test. Using an interrupted time series design, emergency department (ED) admission wait times and rates of patient falls, pressure ulcers and nosocomial MRSA and VRE clinical isolates were compared using GEEs.ResultsPrior to DcCP, bed closures for MRSA and/or VRE isolation were associated with estimated lost hospital charges of $9383 per 100 bed days (95% CI: 8447 to 10 318). No change in ED wait times or change in trend was observed following DcCP. There were significant reductions in monthly expenditures on gowns (−61.0%) and gloves (−16.3%). Patient satisfaction survey results remained stable. No significant changes in rates or trends were observed for patient falls or pressure ulcers. Incidence rates of nosocomial MRSA (1.58 (95% CI: 0.82 to 3.04)) and VRE (1.02 (95% CI: 0.82 to 1.27)) did not significantly change.ConclusionsDcCP was associated with an increase in bed availability and revenue recovery, and a reduction in PPE expenditures. Benefits for other hospital operations metrics and patient outcomes were not identified.
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Brown, David, Helen Neale, Sue Cobb, and Hugh Reynolds. "Development and Evaluation of the Virtual City." International Journal of Virtual Reality 4, no. 1 (January 1, 1999): 27–38. http://dx.doi.org/10.20870/ijvr.1999.4.1.2639.
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house, a supermarket, a café and a transport system. Evaluation of the project was concerned as much with the design of the virtual learning environments (VLEs), issues of usability and access as with monitoring skill learning and transfer to the real world. For three of the VLEs, Supermarket, Café and Transport, a test-retest experimental design method was used. This compared user performance in real world tasks with the same tasks presented in the VLE. Expert assessment was used to evaluate the Virtual House, looking at usability and appropriateness of the learning scenarios. It was found that VLEs can provide interesting, motivating learning environments, which are accessible to users with special needs. Individuals differed in the amount of support required to use the input devices and achieve task objectives in the VLE. Expert and user review methods indicated that the VLEs are seen to be representative of real world tasks and that users are able to learn some basic skills. However, it would be unrealistic to expect transfer of skill over a short experimental time. Further testing is needed to establish the longitudinal learning effects and to develop more reliable techniques to allow users to express their own opinions. Within this project the value of a user centred approach has been demonstrated. The groups involved have provided informed input at each stage of VE development. This has been enhanced by contributions from experts in the field of learning disabilities. The Virtual City has been developed in response to the needs of people with learning disabilities, not in response to their assumed needs.
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Songkram, Noawanit. "Online Course Design for Creativity and Innovative Skills in Virtual Cultural ASEAN Community: From Research to Empirical Practice." International Journal of Emerging Technologies in Learning (iJET) 12, no. 01 (January 31, 2017): 4. http://dx.doi.org/10.3991/ijet.v12i01.6032.
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The first component of learning skills and innovation in the 21st century is creativity and innovative skills. Methods supporting the development of both skills need to be created as a long-term plan and can bring out the benefit. The current education emphasizes on creating changes. To create changes, it is necessary to integrate modern teaching management with principles and theories of learning. The research on Virtual Learning Environment to Enhance 21st Century Skills in Creativity and Innovation of Higher Education Learners in ASEAN Cultural Community can be used to analyze about online learning using modern technology together with learning principles and theories to promote creativity and innovative skills of learners in the 21stcentury. Learning activities were developed to be interesting and challenging. Learners can access to learning sources easily and effectively. Activities were provided on Virtual Learning Environments (VLE) which can enhance students’ learning and experience. Learning was not limited only to a classroom. It was open learning which allowed students to exchange information with instructors, foreign students, foreign friends, and local and international experts without the limit of time and place. Research tools included teaching plan emphasizing of creativity and innovative skills, the test of creativity and innovative skills, and a questionnaire for students. Data was analyzed quantitatively and qualitatively. The results showed that scores of creativity and innovative skills of a sample after studying were higher than that before studying with statistical significance at .05. The course was designed based on 7 steps of learning process: 1. Preparation 2. Identifying a topic or issue to be studied 3. Brainstorm 4. Creating innovation 5. Testing 6. Evaluation and 7. Presentation.
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Sarma, Deesha, So Yeon Kim, and David H. Henry. "Assessing a prognostic model for predicting VTE occurrence in cancer patients." Journal of Clinical Oncology 30, no. 15_suppl (May 20, 2012): 1577. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.1577.
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1577 Background: Venous thromboembolism (VTE) poses a significant health risk to cancer patients and is one of the leading causes of death among this population. The most effective way to prevent VTE and reduce its prominence as a public health burden is by identifying high-risk patients and administering prophylactic measures. In 2008, Khorana et al. developed a model that classified patients by risk based on clinical factors. Methods: We conducted a retrospective study to test this model’s efficacy, on 150 patients with cancer receiving chemotherapy at an outpatient oncology clinic between January 1 and August 1, 2011. We aggregated data and assigned points based on the five factors in the Khorana model: site of cancer with 2 points for very high-risk site and 1 point for high-risk site, 1 point each for leukocyte counts more than 11 x 109/L, platelet counts greater than 350 X 109/L, hemoglobin levels less than 100 g/L and/or the use of erythropoiesis-stimulating agents, and BMI greater than 35 kg/m2 (Khorana et al., Blood 2008). Based on this scoring system, patients with 0 points were grouped into the low-risk category, those with 1-2 points were considered intermediate-risk, and those with 3-4 points were classified as high-risk. Results: As shown in the table, VTE incidence for the low-risk group was 1.9%, intermediate-risk group was 3.9%, and high-risk group was 9.1%. Conclusions: High-risk patients were about 4.5 times more likely to develop a VTE than low risk patients. These results provide valuable insight in determining which patients might benefit from prophylaxis and in motivating the design of prospective clinical trials that assess the VTE predictive model in various ambulatory cancer settings. [Table: see text]
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Muraina, Saheed Adekunle. "EFFECT OF BANK-CHARACTERISTIC AND MACRO-ECONOMIC FACTORS ON LISTED COMMERCIAL BANKS’ PROFITABILITY IN SUB-SAHARAN AFRICA." International Journal of New Economics and Social Sciences 9, no. 1 (June 28, 2019): 51–76. http://dx.doi.org/10.5604/01.3001.0013.3033.
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This study investigated Bank-characteristic and Macro-Economic factors affecting commercial banks’ profitability in Sub Saharan Africa for the period of 2008-2017 using panel data of 56 listed banks drawn from the Sub-Region. Secondary data ex-tracted from the listed Commercial Banks' financial statements were analyzed. The explanatory variables were represented by Credit Risk, Liquidity Risk, Leverage Ratio and Exchange Rate while profitability was represented by Return on Assets (ROA). The study explored a correlational research design to examine the effect of Bank-characteristic and Macro-Economic factors on commercial banks’ profitability. VCE Robust Regressions were employed for the combined banks and country-specific banks’ analysis based on the Hausman Test Specification (fixed and random effects model). Although the Hausman specification test suggested that a fixed effect model is appropriate for the integrated banks’ data analysis, the study used VCE Robust Re-gression to underpin the outcome of the Hausman specification. The study found that Bank-characteristic and macro-economic factors had significantly affected the com-mercial banks' profitability over the study period for the aggregate model of all the banks while only internal factors mainly influenced banks’ profitability for the coun-try-specific banks’ profitability. The Credit Risk had a positive and significant rela-tionship with banks’ profitability while Exchange Rate had a negative and significant relationship with bank profitability during the study period. In controlling foreign exchange rate volatility, Sub-Sahara Africa Clearing Union (SACU) is recommended for Central Banks of member countries to enable them to settle payments for transac-tions within the Sub-region on the basis of multilateral pacts. This will, in turn, reduce the negative effect of an exchange rate increase in the sub-region and subsequently enhance banks’ profitability.
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Wang, Qingfeng, Ming Li, Christopher Monroe, and Yunseong Nam. "Resource-Optimized Fermionic Local-Hamiltonian Simulation on a Quantum Computer for Quantum Chemistry." Quantum 5 (July 26, 2021): 509. http://dx.doi.org/10.22331/q-2021-07-26-509.
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The ability to simulate a fermionic system on a quantum computer is expected to revolutionize chemical engineering, materials design, nuclear physics, to name a few. Thus, optimizing the simulation circuits is of significance in harnessing the power of quantum computers. Here, we address this problem in two aspects. In the fault-tolerant regime, we optimize the Rz and T gate counts along with the ancilla qubit counts required, assuming the use of a product-formula algorithm for implementation. We obtain a savings ratio of two in the gate counts and a savings ratio of eleven in the number of ancilla qubits required over the state of the art. In the pre-fault tolerant regime, we optimize the two-qubit gate counts, assuming the use of the variational quantum eigensolver (VQE) approach. Specific to the latter, we present a framework that enables bootstrapping the VQE progression towards the convergence of the ground-state energy of the fermionic system. This framework, based on perturbation theory, is capable of improving the energy estimate at each cycle of the VQE progression, by about a factor of three closer to the known ground-state energy compared to the standard VQE approach in the test-bed, classically-accessible system of the water molecule. The improved energy estimate in turn results in a commensurate level of savings of quantum resources, such as the number of qubits and quantum gates, required to be within a pre-specified tolerance from the known ground-state energy. We also explore a suite of generalized transformations of fermion to qubit operators and show that resource-requirement savings of up to more than 20%, in small instances, is possible.
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Sulawati, Ity, Amalia Setyati, A. Samik Wahab, and M. Juffrie. "Lateral-flow immunoassay as a diagnostic test for influenza type A and B in children." Paediatrica Indonesiana 48, no. 2 (May 1, 2008): 104. http://dx.doi.org/10.14238/pi48.2.2008.104-9.
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Background The diagnosis of influenza remains difficult toestablish because of its similar symptoms to those of respiratoryinfection caused by other viruses. The “gold standard” for thediagnosis of influenza is viral culture, which takes time to gainthe result and is expensive as well. A simple, rapid, and easilyused tool for detection of influenza virus type A and B is needed.Objective To assess the accuracy of lateral-flow immunoassay withQuick Vue Influenza A+B ® in detecting influenza virus of typeA and B.Methods This was an observational study designed for diagnostictest. The subjects were children aged 0-14 years old presentingwith acute respiratory infection in primary Health Care Jetis ,Godean I, Godean II and Prof. Dr. Sardjito Hospital Yogyakarta,from October 2005 to May 2007. Specimens were collected fromboth the anterior nares and the throat by physicians for lateral-flow immunoassay with Quick Vue Influenza A+B ® and viralculture as gold standard. Lateral-flow immunoassay was done ineach study centre, nasal specimen was placed in an extractionreagent tube and sent to NAMRU II laboratory.Results There were 255 children enrolled in this study. Lateral-flow immunoassay by Quick Vue Influenza A+B ® has sensitivity70% (CI95% 6;83%), specificity 93% (CI95% 90;97%), positivepredictive value 68% (CI95% 54;82%), negative predictive value94% (CI95% 91;97%), positive likelihood ratio 10,56 (CI95%6,14;18,19) and negative likelihood ratio 0,32 (CI95% 0,21; 0,51).Conclusion Lateral-flow immunoassay (Quick Vue InfluenzaA+B ® ), nasal swab specimen is not accurate to detect influenzavirus A and B in children.
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Dutta, Eryn H., Ralph N. Burns, Luis D. Pacheco, Caroline C. Marrs, Aristides Koutrouvelis, and Gayle L. Olson Koutrouvelis. "Lower Extremity Blood Flow Velocity in Obese versus Nonobese Pregnant Women." American Journal of Perinatology 37, no. 04 (February 19, 2019): 384–89. http://dx.doi.org/10.1055/s-0039-1679867.
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Objective Obesity and pregnancy are risk factors for venous thromboembolism (VTE). In nonpregnant individuals, abdominal obesity is associated with venous insufficiency. This study aimed to compare venous Doppler volume flow and velocity in the lower extremities of obese versus nonobese women. Study Design A prospective cohort study was performed. Duplex ultrasound examined bilateral lower extremity venous flow and velocity (time-averaged mean velocity, TAMV). Flow was analyzed at the superficial femoral (SFV), distal external iliac (DEI), common femoral, profunda femoris, and popliteal veins. Mann–Whitney U-test, Spearman's correlation, and chi-square tests were used, with a significance of p < 0.05. Results Left SFV TAMV and volume flow were higher in the obese group (5.1 [4.1–5.7] vs. 2.8 [1.7–3.4] cm/second; p < 0.001) and (89 [73–119] vs. 48 [26–62] cm/minute; p = 0.005). Significant differences were noted for right DEI flow (obese 326 [221–833] vs. nonobese 182 [104–355] cm/minute; p = 0.049). The right femoral profunda flow was also higher in obese (49 [40–93] cm/minute) compared with nonobese (31 [22–52] cm/minute; p = 0.041). Conclusion Volume flow and TAMV in the lower extremities of obese gravidas are higher compared with nonobese ones. Thus, the increased risk of VTE among obese pregnant women may not be caused by venous stasis.
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Gaberson, Kathleen B. "Test Design." Nurse Educator 21, no. 4 (July 1996): 28–33. http://dx.doi.org/10.1097/00006223-199607000-00013.
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Öztürk, Fatma, and Gökhan Kılıçoğlu. "The Relationship between Academic Intellectual Leadership, Perceived Organizational Support and Organization Citizenship: A Study on the Higher Education Institutions in Turkey." Yuksekogretim Dergisi 11, no. 2Pt2 (August 31, 2021): 409–20. http://dx.doi.org/10.2399/yod.20.639356.
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The aim of this study is to test the theoretical model which hypothesizes that academics' academic intellectual leadership affects their perceptions of perceived organizational support and organizational citizenship. In line with this general purpose, it was determined whether the perceptions of academics' intellectual leadership affect their perceptions of perceived organizational support and organizational citizenship. The causal design was used in the study. The sample population of the study is composed of 731 academics working in 13 universities selected by convenience sampling from the Central Anatolia, Aegean, Black Sea and East Anatolia regions of Turkey. The data were collected with Academic Intellectual Leadership Scale, Perceived Organizational Support Scale, and Organizational Citizenship Scale in the 2018-2019 academic year. Mean, standard deviance, and correlation analysis were used for the analysis of the descriptive data, and path analysis was used to test the theoretical model. The findings show that academics' academic intellectual leadership perceptions positively effect their perceptions of perceived organizational support (γ=.24) and organizational citizenship (γ=.38). The results were discussed in light of the relevant literature and suggestions were made to the practitioners, policy makers, and researchers.
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Dave, Jenny, Karan Chawla, Francis Carro-Cruz, Vinay Rao, Jessica Gibilisco, Scott Baumgartner, Katherine Negreira, and Marie Borum. "P014 IBD AND VTE RISK: LET’S TALK ABOUT IT." Inflammatory Bowel Diseases 26, Supplement_1 (January 2020): S51. http://dx.doi.org/10.1093/ibd/zaa010.129.
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Abstract Background Patients with inflammatory bowel disease (IBD) have a 1.5–3 fold increase in the risk of venous thromboembolism (VTE). Additionally, VTE in patients with IBD is associated with a 2.1 fold increase in mortality compared to the general population. The risk of VTE is increased with active inflammation. It is speculated that individuals with IBD are inconsistently advised about VTE risk. This study evaluated the frequency of counseling about VTE in IBD patients. Methods A retrospective medical record review of all IBD patients seen at a university gastroenterology practice during a 5 year period was performed. Patients’ age, gender, disease type and documented counselling about VTE risk were obtained. A database was created maintaining patient confidentiality. Analysis was conducted using Fisher’s Exact Test with significance set at p< 0.05. The study was approved by the university IRB. Results Records of 381 patients were reviewed. There were 209 females and 172 males with a mean age of 44 years (range 20–82). 279 had ulcerative colitis, 96 had Crohn’s disease and 6 had indeterminate colitis. Self-reported ethnicity included 195 White, 97 Black/African-American (AA), 11 Asian, 1 Hawaiian, 34 other and 43 did not report their ethnicity. 13 (3.4%) patients (7 females, 6 males) were counselled about VTE risk. The 7 women who were counselled were <50, with no significant difference in counselling of women <50 compared to women >50 (p=0.11). The 6 men who were counseled were <50, with no significant difference in counseling of men <50 compared to men >50 (p=0.09). There was no difference in the rate of counselling based upon gender (p=1.000), ethnicity (Whites vs. non-Whites, p=0.77; Whites vs. AA, p=1.00) or disease type (p=0.31). Discussion Venous thromboembolism is a known risk of inflammatory bowel disease. While VTEs infrequently occur in IBD patients, it is important that there is awareness about the potential risk. This study revealed that VTE risk is rarely discussed with IBD patients. While this study is limited by single institutional design, size and reliance on documentation, it suggests that increased efforts can be made to educate IBD patients about VTEs. Recognition of VTE risks can improve IBD management and optimize clinical outcomes.
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Abushalha, Kamelah, Sawsan Abulaimoun, Ryan Walters, Sara Albagoush, Hussain I. Rangoonwala, Peter T. Silberstein, and Wael Tuqan. "Inpatient Outcomes and Rates of Venous Thromboembolism and Gastrointestinal Bleeding in Patients with Hepatocellular Carcinoma: Results from Nationwide Inpatient Sample Database 2007-2016." Blood 134, Supplement_1 (November 13, 2019): 2162. http://dx.doi.org/10.1182/blood-2019-132018.
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Background: Patients with hepatocellular carcinoma (HCC) are at an increased risk for developing venous thromboembolism (VTE)- mainly portal venous thrombosis (PVT). Malignancy and liver cirrhosis ( 80%-90% of HCC cases are related to cirrhosis) are conditions that can perturb the hemostatic balance towards a prothrombotic state. Also, these patients with HCC are at high risk for gastrointestinal bleeding (GIB), making thromboprophylaxis and anticoagulation a treatment challenge. Additional information regarding the outcomes and severity of both VTE and GIB in patients with HCC would be useful to guide clinical decision-making Aim: To determine the rates, inpatient mortality, length of stay (LOS) and hospital cost of VTE and GIB-related admissions in patients with hepatocellular carcinoma. Method: We used ICD-9-CM and ICD-10-CM codes to identify hospitalizations from 2007 to 2016 that included HCC with primary discharge diagnoses of GIB or VTE. Linear trends in the rate of GIB and VTE, as well as in-hospital mortality, LOS, and inflation-adjusted hospital cost (in 2016 US dollars), were evaluated using Daniel's test; piecewise slopes were used as needed. All analyses accounted for the NIS sampling design with updated hospital trend weights used as appropriate. SAS v. 9.4 was used for all analyses. Results: Between 2007 and 2016, we identified 6,527,871 hospitalizations with HCC and a primary discharge diagnosis of GIB (3,517,059; 53.9%) or VTE (3,010,812; 46.1%). From 2007 to 2010, a decreasing trend was observed in the rate of GIB diagnoses (55.5% to 51.6%, ptrend < .001), whereas an increasing trend was observed for VTE diagnoses (44.5% to 48.4%, ptrend < .001). By contrast, from 2010 to 2016, an increasing trend was observed in GIB (51.6% to 55.2%, ptrend < .001), whereas a decreasing trend was observed in VTE (48.4% to 44.8%, ptrend < .001). For in-hospital mortality, a decreasing trend was observed for GIB (2.3% to 1.9%, ptrend < .001), whereas a decreasing trend was observed in VTE until 2012 (1.8% to 1.5%, ptrend < .001), after which no trend was indicated (1.5% to 1.6%, ptrend = .337). Although decreasing trends in LOS were observed for GIB (3.4 days to 3.2 days, ptrend < .001) and VTE (4.3 days to 3.3 days, ptrend < .001), increasing trends were observed for inflation-adjusted hospital cost for both GIB ($6,996 to $7,707, ptrend < .001) and VTE ($7,283 to $7,584, ptrend = .048). Conclusion: In this NIS cohort of hospitalized patients with HCC, GIB was more frequently observed than VTE. Trends observed in the rates of GIB and VTE went in opposite directions. In general decreasing trends were observed in in-hospital mortality and LOS for both VTE and GIB. By contrast, increasing trends were observed in the hospital cost for both diagnoses. Clinicians should balance benefits against risks when deciding VTE prophylaxis and treatment in patients with HCC. Future studies are needed to determine the ideal agent and specific dosages to treat HCC-associated VTE. Disclosures No relevant conflicts of interest to declare.
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Dave, Jenny, Karan Chawla, Francis Carro-Cruz, Vinay Rao, Jessica Gibilisco, Scott Baumgartner, Katherine Negreira, and Marie Borum. "P029 VTE RISK WITH IBD PLUS ORAL CONTRACEPTIVES: ARE PATIENTS AWARE?" Inflammatory Bowel Diseases 26, Supplement_1 (January 2020): S58—S59. http://dx.doi.org/10.1093/ibd/zaa010.149.
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Abstract Background The risk of venous thromboembolism (VTE) is 1.5–3 fold higher in individuals with IBD compared to the general population. In addition, combination hormonal oral contraceptives (OCPs) are associated with a 3–5 fold increase in VTE. However, there is limited data regarding VTE risk in women with IBD who are on OCPs. It is speculated that women with IBD who may be at increased risk for VTE occurrence are not consistently counselled about VTE risks. This study evaluated the rate of VTE counselling in reproductive aged women and those on oral contraceptives. Methods A retrospective medical record review of all IBD women seen at a university gastroenterology practice during a 5 year period was performed. Patients’ age, disease type, OCP use and VTE risk counseling were obtained. A database was created maintaining patient confidentiality. Analysis was conducted using Fisher’s Exact Test with significance set at p< 0.05. The study was approved by the university IRB. Results There were 209 female IBD patients with a mean age of 44 years (range 23–82). 153 had ulcerative colitis, 53 had Crohn’s disease and 3 had indeterminate IBD. Self-reported ethnicity included 93 White, 67 Black/African-American, 7 Asian, 1 Hawaiian, 19 other and 22 declined reporting their ethnicity. There were 146 women of reproductive age (<50 years) and 63 women >50 years. 7 women, all age <50, were counselled about potential VTE risk. There was no significant difference (p=0.105) in the rate of VTE counselling in women based upon age. In the 24 women of reproductive age who were on OCPs, one patient was counselled about increased VTE risk. There was no significant difference (p=1.00) in the rate at which women of reproductive age on OCPs (1 in 24, 4.2%) were counselled compared to women of reproductive age who were not on OCPs (6 in 122; 4.9%). Discussion Venous thromboembolism can result in significant morbidity and mortality. Individuals with IBD are at increased risk for VTEs. Women with IBD on oral contraceptives may be at greater risk for VTEs than other IBD patients. This study revealed that IBD women infrequently receive education about VTE risk. There was no significant difference in the rate of counselling in women based upon age. There was also no significant difference in the VTE counselling in women of reproductive age who were on OCPs compared to those who were not on OCPs. Whle this study is limited based upon single institutional design, retrospective evaluation and small sample size, it offers important information for further study and educational initiatives. Enhanced efforts to educate individuals about the risk for VTEs can improve IBD management and outcomes.