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Journal articles on the topic 'Desmodium velutinum'

Author: Grafiati
Published: 4 June 2021
Last updated: 21 June 2025

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1

Ifeanyi Peter Onyeka, Felix Ahamefule Onyegbule, Christopher Obodike Ezugwu, et al. "Gastroprotective effects of Methanol leaf extract of Desmodium velutinum (Fabaceae) and honey on ethanol-induced gastric ulcer in albino rat: The concept of combination therapy." GSC Biological and Pharmaceutical Sciences 20, no. 1 (2022): 167–81. http://dx.doi.org/10.30574/gscbps.2022.20.1.0262.

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Phytochemicals are known for their therapeutic effects through diverse mechanisms such as therapeutic modulators, substrate ligands, receptor ligands, enzyme cofactors, enzymes precursors, toxins scavengers, microbial growth inhibitors, therapeutic agents, and therapeutic enhancers in the treatment of various diseases and ailments. Folklorically, the indigenous people of Nigeria have used Desmodium velutinum (Fabaceae) for treatment of disease conditions such as headache, fever, diarrhea toothaches, ulcers, anti-oxidants, and pains. This study investigated the toxicity, and anti-ulcer effects of a combination of methanol leaf extract of Desmodium velutinum and honey in rats. Anti-ulcer studies were carried out using absolute ethanol rat models of ulceration. The rats were distributed into ten groups of five rats each. Group 1 served as a negative control, group 2 served as a positive control, group 3 served as untreated control, the test groups: groups 4 to 6 received crude extract of Desmodium velutinum at doses of 100, 250, and 500 mg/kg respectively, groups 7 to 9 received a combination of 1 ml honey and crude leaf extract of Desmodium velutinum at doses of 100, 250 and 500 mg/kg while group 10 received 1 ml of honey only. The acute toxicity showed that the extract caused no death in the mice at 5000mg/kg and therefore the LD50 is above 5000mg/kg. The result also showed that 500 mg/kg of the crude extract and 1 ml honey had 42.9% and 71.76 % inhibition of ulceration respectively, while their combination had 100% inhibition of ulceration among the rats treated with the combinations. The combination of methanol leaves extract of Desmodium velutinum and honey exhibited gastrotherapeutic effect in rats and suggest its continued usage as an antiulcer agent for the treatment of ulcer.
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2

Ifeanyi, Peter Onyeka, Ahamefule Onyegbule Felix, Obodike Ezugwu Christopher, et al. "Gastroprotective effects of Methanol leaf extract of Desmodium velutinum (Fabaceae) and honey on ethanol-induced gastric ulcer in albino rat: The concept of combination therapy." GSC Biological and Pharmaceutical Sciences 20, no. 1 (2022): 167–81. https://doi.org/10.5281/zenodo.7124367.

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Phytochemicals are known for their therapeutic effects through diverse mechanisms such as therapeutic modulators, substrate ligands, receptor ligands, enzyme cofactors, enzymes precursors, toxins scavengers, microbial growth inhibitors, therapeutic agents, and therapeutic enhancers in the treatment of various diseases and ailments. Folklorically, the indigenous people of Nigeria have used&nbsp;<em>Desmodium velutinum&nbsp;</em>(Fabaceae) for treatment of disease conditions such as headache, fever, diarrhea toothaches, ulcers, anti-oxidants, and pains. This study investigated the toxicity, and anti-ulcer effects of a combination of methanol leaf extract of&nbsp;<em>Desmodium velutinum&nbsp;</em>and honey in rats. Anti-ulcer studies were carried out using absolute ethanol rat models of ulceration. The rats were distributed into ten groups of five rats each. Group 1 served as a negative control, group 2 served as a positive control, group 3 served as untreated control, the test groups: groups 4 to 6 received crude extract of&nbsp;<em>Desmodium velutinum&nbsp;</em>at doses of 100, 250, and 500 mg/kg respectively, groups 7 to 9 received a combination of 1 ml honey and crude leaf extract of&nbsp;<em>Desmodium velutinum&nbsp;</em>at doses of 100, 250 and 500 mg/kg while group 10 received 1 ml of honey only. The acute toxicity showed that the extract caused no death in the mice at 5000mg/kg and therefore the LD50 is above 5000mg/kg. The result also showed that 500 mg/kg of the crude extract and 1 ml honey had 42.9% and 71.76 % inhibition of ulceration respectively, while their combination had 100% inhibition of ulceration among the rats treated with the combinations. The combination of methanol leaves extract of&nbsp;<em>Desmodium velutinum&nbsp;</em>and honey exhibited gastrotherapeutic effect in rats and suggest its continued usage as an antiulcer agent for the treatment of ulcer.
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3

Makanjuola, Victor O., Saroj Arora, Francis I. O. Duru, and Abraham A. A. Osinubi. "Studies on desmodium velutinum (Willd.) DC. leaf extract's polyphenol profile, in-vitro antioxidant capacity, and anti-proliferative activity of A549 cell lines." Nigerian Journal of Biochemistry and Molecular Biology 38, no. 4 (2023): 184–96. http://dx.doi.org/10.4314/njbmb.v38i4.4.

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In African and Asian ethnomedicinal studies, Desmodium velutinum (Willd) has been used in the treatment of tooth and head aches, diarrhoea, cancer, and haematuria and as repellent and aphrodisiac. The study is aimed at determining polyphenol profile and antioxidant activities of D. velutinum methanol leaf extract and its ethyl acetate and butanol fraction. The study also investigated the effect of this plant on lung adenocarcinoma (A549) cell line. The polyphenol constituents in D. velutinum were evaluated with the U-HPLC technique. While, the antioxidant activities of the methanol plant extract and its fractions were assessed with the DPPH, metal chelating, reducing power and DNA nicking assays. MTT assay was employed to analyse the effect of the plant on A549 cell line. Kaempferol is the principal polyphenol in the leaf extract/fraction of D. velutinum. Conversely, its ethyl acetate fraction possessed a higher concentration of catechin than kaempferol. Total phenolic content (TPC) result was directly proportional to the antioxidant activities of extract and fractions, a higher TPC value was obtained in ethyl-acetate fraction (787.1 ± 21.4 mg GAE/g) than the crude methanol extract (710.9 ± 24.5 mg GAE/g) and its n-butanol fraction (759.2 ± 1.3 mg GAE/g), thus, ethyl acetate fraction performed best in the antioxidant assays. D. velutinum also inhibited oxidative damage to supercoiled plasmid DNA and suppressed the proliferation of A549 cells in a dose-dependent manner. This study shows that D. velutinum does have potentials to protect against many diseases linked with reactive oxygen species.
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4

Kaweetripob, Wirongrong, Sanit Thongnest, Jutatip Boonsombat, et al. "Cytotoxic isoflavonoids from the roots of Desmodium velutinum (Willd.) DC." Phytochemistry Letters 48 (April 2022): 47–53. http://dx.doi.org/10.1016/j.phytol.2022.01.018.

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5

Steven, Eze, P. E, and Ude, C. M. "Preliminary Phytochemical and Lipoprotein Studies of Desmodium velutinum Aqueous Leaves Extract on Albino Wistar Rats." Cross Current International Journal of Medical and Biosciences 1, no. 1 (2019): 1–5. http://dx.doi.org/10.36344/ccijmb.2019.v01i01.001.

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Studies on phytochemical analyses and aqueous leaves extract of Desmodium velutinum was carried using albino Wistar rats. Twenty eight (28) albino wistar rats used for this study were randomly distributed into four groups (I to IV) of seven (7) rats each. Test animals in groups II, III, and IV were initially fed with a high fat diet (10mg/kg) for 12 days. Group II animals remained untreated. The groups III and IV animals were later treated with 5 mg/kg of atorvastatin and 5 mg/kg of D. velutinum, respectively for 4 days. However, the group I rats were fed with normal feed for 12 days and served as the control. The serum total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG) levels were determined from blood samples of the various groups of rats. The result showed that there was a significant (p &lt; 0.05) reduction in the serum TC, HDL-C, LDL-C, and TG concentrations of test animals following the administration of the atorvastatin and the extract. Alkaloids, tannins, flavonoids and reducing sugars were found to be highly present in the crude extract. Other phytochemicals present in the extract were saponins, carbohydrate, steroids, cyanide and terpenoid. These findings indicate that the use of the extract lowered the serum lipid profile of albino wistar rats and may be of clinical importance to individuals at risk of cardiovascular disease.
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6

Steven, P. E., and C. M. Ude. "Hypolipidaemic effect of aqueous extract of Desmodium velutinum leaf on albino wistar rats." Advancement in Medicinal Plant Research 5, no. 4 (2017): 47–50. http://dx.doi.org/10.30918/ampr.54.17.024.

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7

Fred-Jaiyesimi, A. Adediwura, and H. Oluwaseun Ogunlana. "Comparative phytochemical studies and anti-inflammatory activities of Desmodium velutinum (Willd) and Desmodium scorpiurus Desv. (Family Papilionaceae) growing in Nigeria." African Journal of Pharmacy and Pharmacology 10, no. 43 (2016): 909–15. http://dx.doi.org/10.5897/ajpp2015.4357.

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8

Ezike, A. C., P. A. Akah, C. O. Okoli, et al. "STUDIES ON GASTROINTESTINAL EFFECTS OF DESMODIUM VELUTINUM: A TRADITIONAL REMEDY FOR DIARRHEA." American Journal of Pharmacology and Toxicology 9, no. 2 (2014): 114–24. http://dx.doi.org/10.3844/ajptsp.2014.114.124.

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9

Salazar, Daniel E., Luis Guillermo Santos, Peter Wenzl, and Fiona R. Hay. "Effect of dry heat on seed germination of Desmodium and Stylosanthes species." Seed Science and Technology 48, no. 3 (2020): 419–37. http://dx.doi.org/10.15258/sst.2020.48.3.11.

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Mechanical scarification with a scalpel is the best treatment to break physical dormancy and reach high germination percentages in many legumes. However, it is highly time-consuming. Given the ecological relationship between the presence of physical dormancy and high temperatures in tropical grasslands, dry heat treatment could also promote breaking of physical dormancy in Desmodium and Stylosanthes species. This study assessed seed germination of several accessions of nine species of Desmodium and Stylosanthes. Seeds were treated with dry heat (80°C for 30 minutes) and scarified with a scalpel to determine whether dry heat is a reliable alternative treatment to overcome physical dormancy. Mechanical scarification with a scalpel was effective and resulted in high germination for all species. In S. guianensis, both treatments had an equivalent effect, making dry heat a feasible alternative. Dry heat could also be a reliable alternative in D. heterocarpon, D. velutinum, S. hamata, and S. scabra, but tetrazolium tests may be necessary to confirm viability. For D. barbatum and D. scorpiurus, dry heat could be an alternative but further research is needed to confirm this, while in S. capitata and S. viscosa dry heat is not a reliable alternative.
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10

Pathak, Jigyasa, Bhupesh Patel, and Mukesh Kumar Nariya. "Evaluation of Antibacterial Activity and in vitro Antihistaminic Activity of Two Source Plants of Shalaparni, Desmodium gangeticum, and Desmodium velutinum panchanga Powder." Journal of Ayurveda 18, no. 2 (2024): 91–96. http://dx.doi.org/10.4103/joa.joa_79_22.

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11

Igboabuchi, N. "Determination of Proximate, Mineral and Vitamin Composition on the Leaf and Stem of Desmodium velutinum (Willd.) DC." Asian Journal of Biotechnology and Bioresource Technology 1, no. 4 (2017): 1–6. http://dx.doi.org/10.9734/ajb2t/2017/36519.

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12

Nkwocha, C. C., M. O. Ogugofor, I. F. Chukwuma, and O. U. Njoku. "Identification and characterization of phytochemicals and constituents in Desmodium velutinum stem using high-performance liquid chromatography (HPLC)." Pharmacological Research - Modern Chinese Medicine 3 (June 2022): 100090. http://dx.doi.org/10.1016/j.prmcm.2022.100090.

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13

P A, Idakwoji. "Methanol Leaf Extract of Desmodium velutinum (Wild.) D.C. and Acarbose Exhibit Additive Pharmacological Effects in Diabetic Wistar Rats." American Journal of Biomedical Science & Research 14, no. 1 (2021): 99–106. http://dx.doi.org/10.34297/ajbsr.2021.14.001958.

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14

Chinenye, Nkwocha Chinelo, Nworah Florence Nkechi, Okagu Innocent, et al. "Effect of Desmodium velutinum Stem Bark Methanolic Extract on Some Antioxidant Enzymes and Vitamins in Acetaminophen-intoxicated Rats." Research Journal of Medicinal Plants 12, no. 1 (2018): 33–40. http://dx.doi.org/10.3923/rjmp.2018.33.40.

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15

Akuba, B. O., and V. E. O. Ozougwu. "In vitro Inhibition of Carbohydrate Metabolizing Enzymes and in vivo Anti-hyperglycaemic Potential of Methanol Extract of Desmodium velutinum Leaves." Research Journal of Medicinal Plants 12, no. 1 (2018): 48–56. http://dx.doi.org/10.3923/rjmp.2018.48.56.

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16

Mojica-Rodríguez, José Edwin, Edwin Castro-Rincón, Juan Carulla-Fornaguera, and Carlos Eduardo Lascano-Aguilar. "Efecto de la especie y la edad de rebrote en el perfil de ácidos grasos de leguminosas y arbustivas tropicales." Ciencia & Tecnología Agropecuaria 18, no. 3 (2017): 463–77. http://dx.doi.org/10.21930/rcta.vol18_num3_art:738.

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Se evaluó el efecto de tres edades de rebrote (4, 8 y 12 semanas) sobre la producción de forraje, calidad nutricional y perfil de ácidos grasos en leguminosas herbáceas: Clitoria ternatea, Pueraria phaseoloides, Canavalia brasiliensis, Centrosema molle, Centrosema macrocarpum, Alysicarpus vaginalis y Lablab purpureus; en leguminosas arbustivas: Cratylia argentea, Gliricidia sepium, Desmodium velutinum, Cajanus cajan y Leucaena leucocephala; y en una arbustiva no leguminosa: Moringa oleifera (Moringaceae). Se utilizó un diseño de parcelas divididas con bloques al azar, en el cual la parcela principal fue la especie forrajera y la subparcela la edad de rebrote. Los principales ácidos grasos presentes en las especies fueron el ácido palmítico (C16:0), ácido linolénico (C18:3) y linoleico (C18:2). Sin embargo, en las leguminosas herbáceas y arbustivas, el contenido de ácidos grasos fue diferente y disminuyó con la edad de rebrote en los dos grupos. La relación C18:2/C18:3 fue mayor en las leguminosas herbáceas que en las arbustivas, lo cual podría resultar en una mayor concentración de ácido linoleico conjugado (ALC) en la grasa de la leche. La leguminosa Cajanus cajan presentó el mayor (p&lt;0,05) contenido de ácido linolénico (C18:3) y de precursores de ALC en las tres edades de rebrote evaluadas, lo cual sugiere que su uso en la alimentación de bovinos en sistemas de doble propósito resultaría en concentraciones altas de ALC c9 t11 en la grasa de la leche, en comparación con otras especies.
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17

Isah, AO, A. Agunu, and UH Danmalam. "Phytochemical and microscopical evaluation of Desmodium velutinum (P. Beauv.) DC (Papilionaceae) used for pain management in Lokoja, Kogi State, Nigeria." Bayero Journal of Pure and Applied Sciences 8, no. 1 (2015): 123. http://dx.doi.org/10.4314/bajopas.v8i1.21.

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18

Bello, Bello Musawa, Khalid Tukur, Nura Salah Maiakwai, Mustapha Muhammad Sani, and Mukhtar Abubakar Lawal. "Diversity, Composition and Economic Importance of Herbaceous Plants within the Federal Polytechnic Kaura Namoda Campus, Zamfara State, Nigeria." UMYU Scientifica 2, no. 2 (2023): 128–41. http://dx.doi.org/10.56919/usci.2322.014.

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The diversity, composition and economic importance of herbaceous species within the federal polytechnic Kaura Namoda, Zamfara State was studied. The study's objective was to identify, document and evaluate the diversity and abundance of herbaceous species in the study area. The point-centered quarter (PCQ) method was employed in each sampling point. All nearest living herb species encountered were listed. Data obtained were quantitatively analyzed for Relative density (RD) and relative frequency (RF). Species diversity was calculated using Simpson’s index and the Shannon-Weiner index. A total of 64 species of herb were identified belonging to 19 Families. Acanthaceae, Aizoaceae, Cleomaceae, Connaraceae, Laminaceae, Oxalidaceae, and Plantaginaceae had (1) species each. Convolvulaceae, Cucurbitaceae and Euphobiaceae had (2) species each. Apocynaceae, Asteraceae, Malvaceae, Pedaliaceae and Poaceae had (3) species each. Solonaceae is the only family with (4) species. Fabaceae is the only family with the highest number of species (32). A total of 494 individuals of herbaceous species were in the study area. Site A has the highest number of individuals (117), followed by Site D (103), Site C (95) and E (82). Tephrosia pedicellata has the highest species density of 3.2. Leptadenia hastata, Centaurea perrottetii, Gynandropsis gynandra, Euphorbia balsamifera, Senna obtusifolia, Abrus precatorius, Desmodium velutinum, Crotalaria goreensis, Crotalaria pallida var.obovata, Tephrosia pedicellata, Indigofera oblongifolia, Tephrosia vogelii, Tephrosia linearis, Biophytum petersianum, Sesamum radiatum, Solanum lycopersicum has the highest Frequency (100%). Senna tora has the highest relative abundance (5), and Euphorbia balsamifera has a Relative Density of 3.8. Euphorbia balsamifera has the highest relative density of 5, and Ipomea asarifolia has an IVI of 7. Shannon Weiner's diversity index for herbaceous species showed a total of 4.0097. Herbaceous plants are of economic importance; they serve as food, fooder, medicine, fuel, and other purposes. We recommended that there is a need for the conservation of herbaceous species within the Polytechnic to avoid harvesting the herbs for medicinal purposes and animals foraging on the grasses.
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19

SAISORN, WITSANU, and PRANOM CHANTARANOTHAI. "A taxonomic revision of two genera, Pleurolobus and Sohmaea (Leguminosae) in Thailand and Indo-China." Phytotaxa 573, no. 2 (2022): 231–46. http://dx.doi.org/10.11646/phytotaxa.573.2.4.

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There are two species of Pleurolobus and five species of Sohmaea in Thailand and Indo-China. Pleurolobus flexuosus and Sohmaea laxiflora are newly recorded for Cambodia. Taxonomic information of all species is provided. Lectotypes of six names, Desmodium cavaleriei, D. flexuosum, D. laxiflorum, D. macrophyllum, D. ormocarpoides var. velutina, and D. zonatum are designated. One new combination is made as Sohmaea laxiflora subsp. lacei.
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20

Zhu, Yunchi, An Hu, Xinyong Li, Lijuan Luo, and Rongshu Dong. "Identification and Evaluation of the Salt and Acid—Alkaline Resistance of Rhizobium Species of Desmodium." Microbiology Research 16, no. 5 (2025): 106. https://doi.org/10.3390/microbiolres16050106.

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Inoculation with Rhizobium can improve not only host yield and quality but also host adaptability to stress. The match between inoculated strains and hosts and resistance to stress are the key factors determining the inoculation effect. Four types of Desmodium, Pleurolobus gangeticus, Puhuaea sequax, Grona heterocarpos, and Polhillides velutina, were used to capture Rhizobium strains in soil, and the phylogenetic classification and salt and acid—alkaline resistances of the strains were determined through isolation, identification, and different salt and pH treatments. The phylogenetic classification of the 62 rhizobial strains was determined by 16S rDNA analysis. After comparison, the strains were grouped into 10 groups with known strains of rhizobia, including 14 strains of fast-growing rhizobia grouped with Rhizobium tropici and Rhizobium oryzicola and 48 strains of slow-growing rhizobia. The salt tolerance and acid—base adaptability of 52 strains were qualitatively and quantitatively determined in this study, and salt stress was found to have varying effects on the growth of different strains. Some strains grew normally on media with NaCl concentrations of 0.4 and 0.35 mol/L and had strong salt tolerance. The plants grew normally on media with pH 5–9. This study provides theoretical support for the classification of Desmodium and provides efficient Rhizobium strains for the cultivation and application of Desmodium.
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21

Mboungou-Bouesse, Blondy, Arnaud Wilfrid Etou Ossibi, Elva Ngolo, et al. "Hypotensive Effects and Phytochemical Profile of Aqueous Extract and Fractions of &lt;i&gt;Desmodium velutinun&lt;/i&gt; Leaves (Willd) D. C. (Fabaceae) in the Rat." Journal of Biosciences and Medicines 10, no. 08 (2022): 100–109. http://dx.doi.org/10.4236/jbm.2022.108009.

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22

Pathak, Jigyasa, Aswathi M. P., B. R. Patel, Harisha C. R., and Shukla Vinay J. "Microscopic and Phytochemical analysis of Desmodium velutinum (Willd) DC and Desmodium gangeticum (L.) DC. Panchanga powder." Research Journal of Pharmacy and Technology, June 29, 2021, 2950–56. http://dx.doi.org/10.52711/0974-360x.2021.00517.

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Background: Desmodium velutinum (Fabaceae) is one of the wild edible plants used traditionally to treat diarrhoea, haematuria, infertility and also externally used to treat scorpion bites. Though various parts of the plant have been used for therapeutic purpose, panchanga of the plant has not been studied for its Pharmacognostical and phytochemical characteristics in detail, following scientific parameters. Hence in the present study Desmodium velutinum whole plant has been studied for its pharmacognostical and phytochemical characters and compared with commonly used species Desmodium gangeticum. Methods: Whole plant of Desmodim velutinum was collected from Paikmal, Odisha and Desmodium gangeticum was collected from Junagarh, Gujarat in the month of November 2019 following good collection practices and shade dried. Pharmacognostical study and analytical study were performed following standard pharmacopoeial procedures. Results: Whole plant (Panchanga) of former is sweetish and latter is bitter. Powder microscopy of Desmodium gangeticum showed presence of rhomboidal crystals and lignified annular and spiral vessels. Desmodium velutinum showed presence of prismatic crystals and lignified pitted vessels. Physico-chemical analysis showed higher loss on drying in Desmodium gangeticum, and higher water soluble extractive values of Desmodium velutinum. Phytochemical estimation showed the presence of Proteins, tannins, and carbohydrates in both samples. HPTLC study showed similar Rf value 0.82 and 0.94 at 254 and 0.03 and 0.41 at 366nm. Conclusion: Basing upon the analytical and microscopic similarities Desmodium velutinum may be considered as substitute of Desmodium gangeticum
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23

"Desmodium velutinum." CABI Compendium CABI Compendium (January 7, 2022). http://dx.doi.org/10.1079/cabicompendium.18239.

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24

Onyeka, Ifeanyi Peter, Felix Ahamefule Onyegbule, Chioma Ifeoma Ibe, Hope Morris Ifebi, and Christopher Obodike Ezugwu. "Pharmacognostic, Acute Toxicity Profile and Comparative Leaf Characteristics of Desmodium velutinum, Mallotus oppositifolius and Synedrella nodiflora." International Journal of Medical and Pharmaceutical Case Reports, July 23, 2022, 10–24. http://dx.doi.org/10.9734/ijmpcr/2022/v15i430163.

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Plant leaf parameters such as stomatal index, stomata type, leaf microscopic features, and leaf powder microscopy are important taxonomic parameters used to properly identify species and to differentiate one species from another and these is a vital keys in the pharmacognostic study of the medicinal plants because leaf parameters play a vital role in distinguishing crude drugs even when they are fragmented or powdered. Also, extractive index, retention factor, ash value, and phytochemical parameters are vital in the standardization of crude drugs for the establishment of pharmacopeia and monograms. Therefore, the study seeks to validate the use of the phytochemistry and molecular systematics among Asteraceae, Euphorbiaceae, and Fabaceae to support their circumscription and therefore evaluated the pharmacognostic profile of Desmodium velutinum, Synedrella nodiflora and Mallotus oppositifolius folklorically used in South East Nigeria using standard laboratory protocols. The result of the leaf microscopy showed that Desmodium velutinum, Synedrella nodiflora, and Mallotus oppositifolius all had irregular shaped leaf epidermis, and stomata was present only in the abaxial surface respectively. The result showed both D. velutinum and S. nodiflora powder showed the presence of lignin, starch, cystoliths, tannin, and Oil body while calcium oxalate was absent whereas, Mallotus oppositifolius showed the presence of lignin, starch, tannin, and Oil body while calcium oxalate, and cystoliths were absent. Also the result of the TLC showed that M. oppositifolius had 3 visible spots with retention factors (RF) of 0.363, 0.425, and 0.5 in that order respectively, D. velutinum had 4 visible spot with retention factor (RF) of 0.425, 0.5, 0.550 and 0.66 in that order respectively while S. nodiflora had 6 visible spot with retention factor (RF) of 0.255, 0.363, 0.438, 0.538, 0.600 and 0.688 in that order respectively. The result also showed that methanol exhaustible extracted the phytochemicals in the crude dried plant. The acute toxicity studies showed that Desmodium velutinum, Synedrella nodiflora and Mallotus oppositifolius individually had LD50 greater than 5000mg/kg. This study validates the claim that leaf parameters such as stomatal index, stomata type, leaf powder microscopy are important parameters used for the identification of crude drugs.
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Chisom A., Okaroh,, Nwaka Chinyere S, and Nwaka Andrew C. "Evaluation of some Liver Markers and Lipid Peroxidation of Triton-X100-FatInduced Albino Rats Exposed to Water Extract of Desmodium velutinum Stem." IDOSR JOURNAL OF APPLIED SCIENCES, January 11, 2023, 103–13. http://dx.doi.org/10.59298/idosr/2023/12.1.7900.

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This study investigated some Liver Markers and Lipid Peroxidation of Triton-X100-FatInduced Albino Rats Exposed to Water Extract of Desmodium velutinum Stem. A total of thirty (30) male albino rats weighing between 180g and 200g were obtained and randomized into six (6) groups of five (5) rats each. Group A was the negative control group and the rats were fed with grower’s mash and water for 3 days, groups B-F were fed with triton-X100 solution only on the first day to make them hyperlipidemic. Then, group B rats were also fed with grower’s mash and water for 3 days, but, without treatment. Group C rats were fed with grower’s mash and water and were orally administered simvastatin drug for 3 days. Group D rats were fed with grower’s mash and water and were orally administered 50mg/kg of aqueous extract of D. velutinum for 3 days. Group E rats were fed with grower’s mash and water and were orally administered 100mg/kg of aqueous extract of D. velutinum for 3 days and Group F rats were fed with grower’s mash and water and were orally administered 200mg/kg of aqueous extract of D. velutinum for 3 days. At the end of the 3 days feeding period, the blood was collected by cardiac puncture after mild anaesthesia with chloroform, and the biochemical parameters were evaluated using standard methods. Statistical analysis of the results obtained were performed by using ANOVA tests to determine if significant difference exists between the mean of the test and the control group. The limit of significance was set at p&lt;0.05. The results showed that in liver function test, D. velutinum did not increase the liver enzymes. Hence, its consumption could not have adverse effect on the liver. This result showed that there was a significant increase (p&lt;0.05) in liver markers in hyperlipidemic untreated groups compared to normal control. Also, there was a significant decrease (p&lt;0.05) of hyperlipidemic treated with 200mg of D.velutinum compared to hyperlipidemic untreated. Keywords: Liver Markers, Lipid Peroxidation, Triton-X100, Albino rats and Desmodium velutinum Stem.
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26

"An appraisal on Ethnomedicinal Claims and Pharmacological Activities of Desmodium velutinum(Willd.) D.C." International Journal of Pharmaceutical Research 12, no. 02 (2020). http://dx.doi.org/10.31838/ijpr/2020.12.02.0085.

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27

Nkwocha, Chinelo, Martins Ogugofor, and Ifeoma Chukwuma. "Identification and Characterization of Phytochemicals and Constituents in Desmodium Velutinum Stem Using High Performance Liquid Chromatography (Hplc)." SSRN Electronic Journal, 2022. http://dx.doi.org/10.2139/ssrn.4006028.

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28

"Caspase Dependent Inhibitory Effect of the Growth of HeLa Cells by Desmodium velutinum (Willd.) DC. Ethanol Leaf Extract." Tropical Journal of Natural Product Research 6, no. 1 (2022): 167–70. http://dx.doi.org/10.26538/tjnpr/v6i1.27.

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29

"Evaluation of antioxidant activity and nutritional value of Desmodium velutinum(Willd.) D.C. leaves: A folklore plant of Orissa." International Journal of Pharmaceutical Research 12, no. 03 (2020). http://dx.doi.org/10.31838/ijpr/2020.12.03.202.

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30

"Evaluation of antioxidant activity and nutritional value of Desmodium velutinum(Willd.) D.C. leaves: A folklore plant of Orissa." International Journal of Pharmaceutical Research 12, no. 03 (2020). http://dx.doi.org/10.31838/ijpr/2020.12.03.206.

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31

E., Ngolo, Etou Ossibi A.W., Epa C., et al. "Effet hypotenseur de l’extrait aqueux de la recette à base de Brillantaisia patula T. Anderson (Acanthaceae) et de Desmodium velutinum (Willd) D.C (Fabaceae) chez lerat." International Journal of Multidisciplinary and Current Research 6, no. 6 (2018). http://dx.doi.org/10.14741/ijmcr/v.6.6.20.

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L’objectif de ce travail était d’étudier les effets hypotenseurs et le mécanisme d’action de l’extrait aqueux de la recette à base de B.patula et de D.velutinum sur la pression artérielle et la fréquence cardiaque chez le rat normotendu anesthésié à l’uréthane à 15% à raison de 1,5 g/kg, i.p. L’extrait aqueux de la recette aux doses de 5, 20, 40 et 80 mg/kg provoque une baisse significative de la PAS et de la FC. L’effet hypotenseur est inhibé partiellement par l’atropine (1mg/kg, i.v) à 41,96 % et l’étude comparée des effets de la recette à 20 mg/kg avec l’acétylcholine (10 µg/kg) montre des similitudes de la baisse de la PAS ; ce qui suggère que cet extrait agit via les récepteurs muscariniques. Par ailleurs, l’administration de l’adrénaline (50 µg/kg) chez les rats normotendus (n = 5) provoque une augmentation de la pression artérielle à 140,79 ± 35,15 %. Cependant, l’administration de l’extrait aqueux de la recette (20 mg/kg) s’oppose à cette augmentation de la pression artérielle. Cet extrait s’oppose aussi à l’augmentation de la pression artérielle induite par le L-NAME. L’administration de l’extrait à la même dose après la bivagotomie ne provoque pas une baisse de la pression artérielle ; après la bi occlusion carotidienne, cet extrait empêche l’augmentation significative de la pression artérielle. Ces résultats montrent que l’effet hypotenseur de l’extrait ne passe pas seulement par l’inhibition du système nerveux sympathique mais implique aussi partiellement la stimulation du système nerveux parasympathique. En conclusion, ces résultats justifient, au moins en partie, l’utilisation de l’extrait aqueux de la recette à base de B.patula et D.velutinum dans le traitement de l’hypertension artérielle.
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32

Bir, S. S., and Santosh Kumari. "Additions to the Papilionaceous Flora of Pachmarhi Hills, Madhya Pradesh." Nelumbo, May 21, 2024, 45–50. http://dx.doi.org/10.20324/nelumbo/v22/1980/75357.

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Thirty nine species of Papilionaceae are reported for the first time from Pachmarhi in Madhya Pradesh. This makes a total record of 99 species (103 taxa) of Papilionaceous plants from the region. As many as 9 species, namely, Argyrolobium flactidum, Atylosia kulnensis, Desmodium floribundum D. maculatum, Flemingia fruticulosa Phasealus velutinus, Shuteria, vestita, Sophora mollis and Teramnus mollis are new records for Madhya Pradesh. This fully justifies the need for intensive floristic surveys of the restricted regions for compilation of Flora of India.
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