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1

Gupta, Disha. "Abstract No. : ABS2592: Medial branch block versus medial branch radiofrequency ablation in patients with lumbar facet joint pain." Indian Journal of Anaesthesia 66, Suppl 1 (2022): S88. http://dx.doi.org/10.4103/0019-5049.340755.

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Background and Aims: Lumbar facet joint related pain is reported to have a prevalence of 15-45%.This prospective study was conducted to compare the efficacy of medial branch block with medial branch radiofrequency(RF) ablation in patients with lumbar facet joint pain. Methods: Forty-six participants were randomised to Group-I (n=24) or Group-II (n=22). In Group-I, patients received fluoroscope guided medial branch block with 2ml drug solution comprising of 0.25% bupivacaine plus 10mg of triamcinolone and in Group-II, patients received fluoroscope guided medial branch radiofrequency ablation at
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Asy’ari, Nur Aini Shofiya. "Peran Kampanye Tematik Iklan A Mild Dalam Membentuk Brand Image Rokok A Mild." LINIMASA: JURNAL ILMU KOMUNIKASI 1, no. 2 (2018): 45. http://dx.doi.org/10.23969/linimasa.v1i2.1081.

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ABSTRAK
 Iklan dalam paradigma wacana merupakan model komunikasi yang mengkomunikasikan citra secara maksimum dalam waktu yang minimum dan diharapkan dapat mencapai sasaran dan memberikan keuntungan kepada produsen. Karena pengaruhnya yang sangat besar maka khusus untuk iklan rokok dibatasi ruang geraknya oleh undang-undang No.24 tahun 1997 tentang Penyiaran, Tata Krama serta Tata Cara Periklanan Bab II Poin C butir 7. Hal ini menjadi stimulus bagi produsen iklan rokok untuk lebih kreatif dalam menyampaikan pesan. Iklan rokok A Mild memilih untuk memproduksi iklan dengan mengangkat fenome
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Jones, Vivian Truong, Ramona Graves-Deal, Zheng Cao, et al. "Abstract 2001: Autocrine HGF maturation as a targetable regulatory step in cetuximab resistance in colorectal cancer." Cancer Research 84, no. 6_Supplement (2024): 2001. http://dx.doi.org/10.1158/1538-7445.am2024-2001.

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Abstract Although amplifications and mutations in receptor tyrosine kinases (RTKs) act as bona fide oncogenes, in most cancers, RTKs maintain moderate expression and remain wild-type. Consequently, cognate ligands control many facets of tumorigenesis, including resistance to anti-RTK therapies. Herein, we show that the ligands for the RTKs MET and RON, HGF and HGFL, respectively, are synthesized as inactive precursors that are activated by cellular proteases. Our newly generated HGF/HGFL protease inhibitors could overcome both de novo and acquired cetuximab resistance in colorectal cancer (CRC
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Galabova, Gergana, Michael Almstetter, Nicole Brusis, et al. "Abstract 1732: Mastering metastases by novel selective CDK9 Inhibitor ORI-15412." Cancer Research 85, no. 8_Supplement_1 (2025): 1732. https://doi.org/10.1158/1538-7445.am2025-1732.

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Abstract Metastases, the leading cause of cancer-related morbidity and deaths, remain a major therapeutic challenge, highlighting the critical need for novel treatments. Our study evaluates the efficacy of ORI-15412, an oral and fully brain-penetrant CDK9 inhibitor developed by Origenis, designed to meet this need through selective inhibition of CDK9 and modulation of key pathways involved in cancer progression and metastasis. ORI-15412 was engineered using Origenis' proprietary technologies - MOREsystem®, MolMind®, BRAINstorm™, and Cippix® - for optimized blood-brain barrier penetration, sele
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Petrov, Philipp. "Augustine's Literary Legacy as Research Focus in Contemporary Scholarship." Hypothekai 8 (May 2024): 135–67. http://dx.doi.org/10.32880/2587-7127-2024-8-8-135-167.

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The views on the soul in the philosophical-theological thought of Au-relius Augustine (354–430 AD) hold a special place. When considering practically any of his teachings—whether it be his doctrine on the cosmos, time, memory, the relationship between free will and divine predestination, or his philosophy of history and pedagogy—we are inevitably compelled to take them into account or directly engage with them. His works are also associated with the so-called "psychologism" of Augustine, a concept high-lighted by numerous scholars delving into his truly vast creative heritage. The purpose of t
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Fernandez, Estefania, Samuel Cass, Yongwoo D. Seo, et al. "Abstract 2806: A single dose of perioperative cefazolin disrupts the gut microbiome and immunity in patients (pts) with early-stage melanoma." Cancer Research 84, no. 6_Supplement (2024): 2806. http://dx.doi.org/10.1158/1538-7445.am2024-2806.

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Abstract Background: Perioperative antibiotic prophylaxis is routinely utilized to reduce surgical site infections (SSIs). However, the rate of SSIs following a clean surgical procedure is <3%. Overuse of antibiotics is associated with potential adverse effects, including disruption of the composition and function of the native gut microbiota. Numerous studies have shown a negative impact of antibiotics on response and survival in patients with cancer treated with immune checkpoint blockade. The primary objective of this study was to determine the impact of a single dose of perioperativ
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Galabova, Gergana, Michael Almstetter, Nicole Brusis, et al. "Abstract 3024: The novel selective CDK9 Inhibitor ORI-15412 reduces PD-L1 expression and drives the efficacy in combination therapies for melanoma and triple-negative breast cancer." Cancer Research 85, no. 8_Supplement_1 (2025): 3024. https://doi.org/10.1158/1538-7445.am2025-3024.

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Aggressive cancers like melanoma and triple-negative breast cancer (TNBC) are challenging to treat due to limited therapeutic options and high relapse rates. Advances in combination therapies offer promise by targeting multiple cancer progression and resistance pathways. This study explores ORI-15412, Origenis' novel, oral CDK9 inhibitor, as monotherapy and in combination therapies in syngeneic melanoma (B16F10) and TNBC (4T1) murine models. ORI-15412, developed with Origenis' proprietary MOREsystem®, MolMind®, BRAINstorm™, and Cippix® technologies, shows unhindered brain penetration, high sel
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8

Hegarty, Dominic A. "Multivariate Prognostic Modeling of Persistent Pain Following Lumbar Discectomy." Pain Physician 5;15, no. 5;9 (2012): 421–34. http://dx.doi.org/10.36076/ppj.2012/15/421.

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Background: Persistent postsurgical pain (PPSP) affects between 10% and 50% of surgical patients, the development of which is a complex and poorly understood process. To date, most studies on PPSP have focused on specific surgical procedures where individuals do not suffer from chronic pain before the surgical intervention. Individuals who have a chronic nerve injury are likely to have established peripheral and central sensitization which may increase the risk of developing PPSP. Concurrent analyses of the possible factors contributing to the development of PPSP following lumbar discectomy ha
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Hasanov, Merve, Simin Kiany, Marie-Andrée Forget, et al. "Abstract 3605: Phase II study of pembrolizumab in conjunction with lymphodepletion, TIL ACT, and high- or low-dose IL-2 in patients with metastatic melanoma." Cancer Research 84, no. 6_Supplement (2024): 3605. http://dx.doi.org/10.1158/1538-7445.am2024-3605.

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Abstract Background: In metastatic melanoma (MM) patients (pts), adoptive cell transfer (ACT) using tumor-infiltrating lymphocytes (TIL) can yield lasting responses. However, TIL ACT with high-dose IL-2 has notable toxicities. Anti-PD1 (pembrolizumab) is FDA approved for MM treatment. Our study aimed to merge TIL infusion with anti-PD1 in two arms, comparing high (HD, arm 1) and low (LD, arm 2) IL-2 doses. Methods: After tumor harvest and TIL expansion, pts were lymphodepleted with cyclophosphamide and fludarabine, followed by infusion with their ex-vivo expanded TIL combined with IL-2 (arm 1:
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Pacharne, Suruchi, Oliver M. Dovey, Jonathan L. Cooper, et al. "Setbp1 Overexpression Acts in the Place of Class-Defining Somatic Mutations to Drive Mouse and Human FLT3-ITD-Mutant AMLs." Blood 136, Supplement 1 (2020): 31–32. http://dx.doi.org/10.1182/blood-2020-141743.

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Setbp1 overexpression acts in the place of class-defining somatic mutations to drive mouse and human FLT3-ITD-mutant AMLs Suruchi Pacharne,1,2 Oliver M. Dovey,1 Jonathan L. Cooper,1 Muxin Gu,1,2 MS Vijaybaskar,1,2 Mathias J. Friedrich,1,5 Malgorzata Gozdecka,1,2 Sandeep S. Rajan,1,4, Etienne De Braekeleer,1,2 Maxim Barenboim,5,6 Grace Collord,1,2 Hannes Ponstingl,1 Ruben Bautista,1 Milena Mazan,1,8 Roland Rad,5,6 Konstantinos Tzelepis,1,7 Penny Wright,3 and George S. Vassiliou1,2,9* Abstract Internal tandem duplications in FLT3 (FLT3-ITD) are found in 30% of acute myeloid leukemia (AML) cases
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ATKINSON, RONALD R. "CONTRASTING APPROACHES TO WRITING INTRODUCTORY TEXTS Medieval Africa, 1250–1800. By ROLAND OLIVER and ANTHONY ATMORE. Cambridge: Cambridge University Press, 2001. Pp. viii+251. £40; $59.95 (ISBN 0-521-79024-7); £14.95; $21.95, paperback (ISBN 0-521-79372-6). Introduction to the History of African Civilization, Volume II: Colonial and Post-Colonial Africa. By C. MAGBAILY FYLE. Lanham MD: University Press of America, 2001. Pp. xii+190. $36, paperback (ISBN 0-7618-2107-4)." Journal of African History 44, no. 3 (2003): 507–8. http://dx.doi.org/10.1017/s0021853703218661.

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Xing, Fei, Yi Ping Yao, Zhi Wen Jiang, and Bing Wang. "Fine-Grained Parallel and Distributed Spatial Stochastic Simulation of Biological Reactions." Advanced Materials Research 345 (September 2011): 104–12. http://dx.doi.org/10.4028/www.scientific.net/amr.345.104.

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To date, discrete event stochastic simulations of large scale biological reaction systems are extremely compute-intensive and time-consuming. Besides, it has been widely accepted that spatial factor plays a critical role in the dynamics of most biological reaction systems. The NSM (the Next Sub-Volume Method), a spatial variation of the Gillespie’s stochastic simulation algorithm (SSA), has been proposed for spatially stochastic simulation of those systems. While being able to explore high degree of parallelism in systems, NSM is inherently sequential, which still suffers from the problem of l
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13

A., D. Jadhav, and V. Sathe T. "Host preference by Uzifly Exorista bombycis L. in pure line bivoltine breeds FC1 and FC2 (Bombyx mori L.) and Economical loss in seed cocoon production." Biolife 4, no. 1 (2022): 88–93. https://doi.org/10.5281/zenodo.7310231.

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&nbsp; <strong>ABSTRACT</strong> &nbsp;&nbsp;&nbsp;&nbsp; Host preference by Uzifly <em>Exorista bombycis</em> L. (Diptera : Tachinidae) to pure line bivoltine breeds FC1 and FC2 (<em>Bombyx mori</em> L.) and economical loss in seed cocoon production have been studied.&nbsp; The result indicated that FC1 produced more yield and was less susceptible to uzifly attack (10%) while FC2 was more susceptible to uzify attack (30%) FC1 x FC2 (double hybrid) was very interestingly, also found least susceptible to uzifly attack (6%).&nbsp; The net gross income reduction noted in FC1 x FC2, FC1 and FC2 wa
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Pham, Nghia-Luan, and Van-Vinh Nguyen. "Adaptation in Statistical Machine Translation for Low-resource Domains in English-Vietnamese Language." VNU Journal of Science: Computer Science and Communication Engineering 36, no. 1 (2020). http://dx.doi.org/10.25073/2588-1086/vnucsce.231.

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In this paper, we propose a new method for domain adaptation in Statistical Machine Translation for low-resource domains in English-Vietnamese language. Specifically, our method only uses monolingual data to adapt the translation phrase-table, our system brings improvements over the SMT baseline system. We propose two steps to improve the quality of SMT system: (i) classify phrases on the target side of the translation phrase-table use the probability classifier model, and (ii) adapt to the phrase-table translation by recomputing the direct translation probability of phrases.&#x0D; &#x0D; Our
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15

"Rezensionen." Das Mittelalter 20, no. 1 (2015): 177–220. http://dx.doi.org/10.1515/mial-2015-0011.

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Gerd Althoff, „Selig sind, die Verfolgung ausüben“. Päpste und Gewalt im Hochmittelalter. Stuttgart, Konrad Theiss Verlag 2013, 254 S. (Wendelin Knoch: Hattingen, E-Mail: wendelin.knoch@ruhr-uni-bochum.de) Günter Bayerl, Technik in Mittelalter und Früher Neuzeit. Stuttgart, Konrad Theiss Verlag GmbH 2013. 199 S. 101 Abb. (Christian Scholl: Münster, E-Mail: christian.scholl@uni-muenster.de) Andrea Beck/Andreas Berndt (Hgg.), Sakralität und Sakralisierung. Perspektiven des Heiligen (Beiträge zur Hagiographie 13). Stuttgart, Franz Steiner 2013. 210 S. (Peter Gemeinhardt: Göttingen, E-Mail: Peter.
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Zadik, Zvi, Nataliya Zelinska, Violeta Iotova, et al. "OR21-04 Long-term Efficacy And Safety Of Once-weekly Somatrogon In Pediatric Subjects With Growth Hormone Deficiency: Results From Up To 8 Years Of Somatrogon Treatment." Journal of the Endocrine Society 7, Supplement_1 (2023). http://dx.doi.org/10.1210/jendso/bvad114.1522.

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Abstract Disclosure: Z. Zadik: None. N. Zelinska: Consulting Fee; Self; Novo Nordisk, Berlin-Chemie, Medtronic, Sanofi-Aventis. Research Investigator; Self; MacroGenics, Novo Nordisk, Pfizer, Inc., Merck, OPKO Health, Ferring Pharmaceuticals, Teva Pharmaceutical Industries Ltd., Parexel, Genexine. Speaker; Self; Medtronic, Berlin-Chemie, ACINO, Novo Nordisk, Pfizer, Inc., Sanofi-Aventis, Johnson &amp;Johnson, Wörwag Pharma. V. Iotova: Grant Recipient; Self; Pfizer, Inc. Speaker; Self; Novo Nordisk, Pfizer, Inc., Swixx, Sandoz, Berlin-Chemie. Y. Skorodok: None. O.A. Malievskiy: None. N. Mauras:
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17

"Acknowledgment of Abstract Graders." Circulation 124, suppl_21 (2011). https://doi.org/10.1161/circ.124.suppl_21.a401.

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We would like to thank the following abstract graders for their invaluable time and effort in reviewing abstracts for Scientific Sessions 2011. Brian Abbott Friederike K. Keating Geoffrey Abbott John Kern Evan Abel Karl Kern Benjamin S. Abella Morton Kern Theodore Abraham Amit Khera William T. Abraham Raymond J. Kim Stephan Achenbach Sue Kimm Michael A. Acker Carey D. Kimmelstiel Michael J. Ackerman Jacobo Kirsch David H. Adams Joel Kirsh M. Jacob Adams Lorrie Kirshenbaum Ted Adams Raj Kishore Philip A. Ades Masafumi Kitakaze Gail K. Adler Andre Kleber Sunil K. Agarwal Neil S. Kleiman Frank Ag
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Mussari, Mark. "Umberto Eco Would Have Made a Bad Fauve." M/C Journal 5, no. 3 (2002). http://dx.doi.org/10.5204/mcj.1966.

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"The eye altering, alters all." - Blake In his essay "How Culture Conditions the Colours We See," Umberto Eco claims that chromatic perception is determined by language. Regarding language as the primary modeling system, Eco argues for linguistic predominance over visual experience: ". . . the puzzle we are faced with is neither a psychological one nor an aesthetic one: it is a cultural one, and as such is filtered through a linguistic system" (159). Eco goes on to explain that he is 'very confused' about chromatic effect, and his arguments do a fine job of illustrating that confusion. To Eco'
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"Acknowledgment of Abstract Graders." Circulation 126, suppl_21 (2012). https://doi.org/10.1161/circ.126.suppl_21.a401.

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Abbara, Suhny Georgiou, Demetrios naka, yoshifumi Abbott, Brian Gerszten, Robert Nakagawa, Yoshihisa Abbott, Geoffrey . Gewillig, Marc Nakamura, Kazufumi Abe, Jun-ichi Ghali, Jalal K. Nakamura, Yasuyuki Abella, Benjamin S. Ghanayem, Nancy Nakanishi, Toshio Abraham, Theodore Ghanayem, Nancy Nakatani, Toshio Abraham, William T. Ghosh, Shobha Narayan, Sanjiv M. Achenbach, Stephan Giachelli, Cecilia M. Natale, Andrea Acker, Michael A. Gidding, Samuel S. Natarajan, Rama Ackerman, Michael J. Gidding, Samuel S. Nattel, Stanley Adams, M. Jacob Gilchrist, Ian Nazarian, Saman Adams, Ted Giles, Thomas D.
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sprotocols. "Generation of high quality multi-view confocal 3D datasets of zebrafish larval brains suitable for analysis using Virtual Brain Explorer (ViBE-Z) software." January 9, 2015. https://doi.org/10.5281/zenodo.13863.

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Authors: Meta Rath, Roland Nitschke, Alida Filippi, Olaf Ronneberger &amp; Wolfgang Driever ### Abstract In this protocol we describe a method to produce multi-view confocal 3D datasets suitable to be processed by the Virtual Brain Explorer (ViBE-Z) software. The method is optimized for Zebrafish (Danio rerio) embryos and larvae from one to five days post fertilization, but may be used also for other small biological objects. Zebrafish larvae are stained using either fluorescent in situ hybridization or immunostaining. In addition, all samples are counterstained with a nuclear stain to generat
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"Buchbesprechungen." Zeitschrift für Historische Forschung: Volume 48, Issue 3 48, no. 3 (2021): 533–644. http://dx.doi.org/10.3790/zhf.48.3.533.

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Domeier, Norman / Christian Mühling (Hrsg.), Homosexualität am Hof. Praktiken und Diskurse vom Mittelalter bis heute (Geschichte und Geschlechter, 74), Frankfurt a. M. / New York 2020, Campus, 401 S. / Abb., € 39,95. (Martin Dinges, Stuttgart) Hengerer, Mark / Nadir Weber (Hrsg.), Animals and Courts. Europe, c. 1200 – 1800, Berlin / Boston 2020, de Gruyter Oldenbourg, VII u. 434 S. / Abb., € 89,95. (Stefano Saracino, Jena / München) Baumann, Anette / Alexander Jendorff / Frank Theisen (Hrsg.), Religion – Migration – Integration. Studien zu Wechselwirkungen religiös motivierter Mobilität im vor
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Allmark, Panizza. "Photography after the Incidents." M/C Journal 10, no. 6 (2008). http://dx.doi.org/10.5204/mcj.2719.

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&#x0D; &#x0D; &#x0D; This article will look at the use of personal photographs that attempt to convey a sense of social activism as a reaction against global terrorism. Moreover, I argue that the photographs uploaded to the site “We’re Not Afraid”, which began after the London bombings in 2005, presents a forum to promote the pleasures of western cultural values as a defence against the anxiety of terror. What is compelling are the ways in which the Website promotes, seemingly, everyday modalities through what may be deemed as the domestic snapshot. Nevertheless, the aura from the context of t
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Collins, Steve. "Amen to That." M/C Journal 10, no. 2 (2007). http://dx.doi.org/10.5204/mcj.2638.

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&#x0D; &#x0D; &#x0D; In 1956, John Cage predicted that “in the future, records will be made from records” (Duffel, 202). Certainly, musical creativity has always involved a certain amount of appropriation and adaptation of previous works. For example, Vivaldi appropriated and adapted the “Cum sancto spiritu” fugue of Ruggieri’s Gloria (Burnett, 4; Forbes, 261). If stuck for a guitar solo on stage, Keith Richards admits that he’ll adapt Buddy Holly for his own purposes (Street, 135). Similarly, Nirvana adapted the opening riff from Killing Jokes’ “Eighties” for their song “Come as You Are”. Mus
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Ryan, John C., Danielle Brady, and Christopher Kueh. "Where Fanny Balbuk Walked: Re-imagining Perth’s Wetlands." M/C Journal 18, no. 6 (2016). http://dx.doi.org/10.5204/mcj.1038.

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Special Care Notice This article contains images of deceased people that might cause sadness or distress to Aboriginal and Torres Strait Islander readers. Introduction Like many cities, Perth was founded on wetlands that have been integral to its history and culture (Seddon 226–32). However, in order to promote a settlement agenda, early mapmakers sought to erase the city’s wetlands from cartographic depictions (Giblett, Cities). Since the colonial era, inner-Perth’s swamps and lakes have been drained, filled, significantly reduced in size, or otherwise reclaimed for urban expansion (Bekle). N
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