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1

Şahan, Mehmet Hamdi, Mikail Inal, Nuray Bayar Muluk, and Gökçe Şimşek. "Cribriform Plate, Crista Galli, Olfactory Fossa and Septal Deviation." Current Medical Imaging Formerly Current Medical Imaging Reviews 15, no. 3 (2019): 319–25. http://dx.doi.org/10.2174/1573405614666180314150237.

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Objectives: In the present study, we investigated the relationship between olfactory fossa, cribriform plate, crista galli and nasal Septal Deviation (SD). Keros classification of olfactory fossa was also performed. Methods: This study was performed retrospectively. Computerized Tomography (CT) images of 200 adult subjects were observed. Unilateral nasal Septal Deviation (SD) cases were included into the study. On coronal CT scans, SD side and location, SD angle, cribriform plate width, olfactory fossa depth (Keros classification) and width, area of the olfactory fossa, crista galli length, wi
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2

Huong, Pham V., Stéphanie Bouchet, and Jean-Claude Launay. "Cristal-growth dynamics of n-doped gaAs." Proceedings, annual meeting, Electron Microscopy Society of America 50, no. 2 (1992): 1544–45. http://dx.doi.org/10.1017/s0424820100132352.

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Microstructure of epitaxial layers of doped GaAs and its crystal growth dynamics on single crystal GaAs substrate were studied by Raman microspectroscopy with a Dilor OMARS instrument equipped with a 1024 photodiode multichannel detector and a ion-argon laser Spectra-Physics emitting at 514.5 nm.The spatial resolution of this technique, less than 1 μm2, allows the recording of Raman spectra at several spots in function of thickness, from the substrate to the outer deposit, including areas around the interface (Fig.l).The high anisotropy of the LO and TO Raman bands is indicative of the orienta
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3

Gómez B., Javier, Mariano Vela M., and Melchor Llosa D. "EVALUACIÓN DE LA DIMENSIÓN DE LA ZONA SENSIBLE DE UN DETECTOR SEMICONDUCTOR COAXIAL DE GeHP." Revista de Investigación de Física 7, no. 01-02 (2004): 76–78. http://dx.doi.org/10.15381/rif.v7i01-02.8820.

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En este trabajo se presenta el comportamiento de la sensibilidad de un detector coaxial de GeHP respecto de la llegada del haz de radiación colimado en la dirección frontal como lateral. Los resultados muestran que, para una configuración horizontal o vertical del criostato, existe una dirección preferencial de detección. A partir de los perfiles de sensibilidad se obtuvo un estimado de la dimensión sensible del cristal semiconductor del detector.
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4

John, George B., Yonglei Shang, Li Li, et al. "The Mitochondrial Inner Membrane Protein Mitofilin Controls Cristae Morphology." Molecular Biology of the Cell 16, no. 3 (2005): 1543–54. http://dx.doi.org/10.1091/mbc.e04-08-0697.

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Mitochondria are complex organelles with a highly dynamic distribution and internal organization. Here, we demonstrate that mitofilin, a previously identified mitochondrial protein of unknown function, controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. Down-regulation of mitofilin in HeLa cells by using specific small interfering RNA lead to decreased cellular proliferation and increased apoptosis, suggesting abnorma
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5

Balassone, Giuseppina, Valentina Scognamiglio, Fernando Nieto, et al. "The nature of Zn-phyllosilicates in the nonsulfide Mina Grande and Cristal zinc deposits (Bongará District, Northern Peru): The TEM-HRTEM and AEM perspective." American Mineralogist 105, no. 8 (2020): 1223–41. http://dx.doi.org/10.2138/am-2020-7140.

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Abstract Zn-phyllosilicates are common minerals in nonsulfide Zn deposits and can give crucial information about the genesis of these oxidized mineralizations. They seldom represent the prevailing economic species but might have a significant impact on mineral processing. This study has been carried out on the Mina Grande and Cristal Zn-sulfide/nonsulfide deposits, which occur in the Bongará district (Amazonas region, northern Peru). The Cristal and Mina Grande orebodies are hosted by the sedimentary (prevailingly carbonate) successions of the Pucará Group (Condorsinga formation, Lower Jurassi
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6

Weber, Daniela, Susana Gorzalczany, Virginia Martino, Cristina Acevedo, Olov Sterner, and Timm Anke. "Metabolites from Endophytes of the Medicinal Plant Erythrina crista-galli." Zeitschrift für Naturforschung C 60, no. 5-6 (2005): 467–77. http://dx.doi.org/10.1515/znc-2005-5-616.

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Erythrina crista-galli (Fabaceae) is used in Argentinean ethnopharmacology as anti-inflammatory medication, narcotic, desinfectant, and for the treatment of wounds. The common name of the tree is “ceibo“ or coral tree. The dominating endophytes in E. crista-galli all belong to the genus Phomopsis as identified by microscopic features and the analysis of their ITS sequences. To investigate a possible contribution of Phomopsis spp. to the metabolites found in the plant, twelve different isolates were cultivated in different media. Besides several new metabolites a number of known compounds were
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7

Ern, Manfred, Dirk Offermann, Peter Preusse, Klaus-Ulrich Grossmann, and Jens Oberheide. "Calibration procedures and correction of detector signal relaxations for the CRISTA infrared satellite instrument." Applied Optics 42, no. 9 (2003): 1594. http://dx.doi.org/10.1364/ao.42.001594.

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8

Toth, Alexandra, Axel Meyrat, Stefan Stoldt, et al. "Kinetic coupling of the respiratory chain with ATP synthase, but not proton gradients, drives ATP production in cristae membranes." Proceedings of the National Academy of Sciences 117, no. 5 (2020): 2412–21. http://dx.doi.org/10.1073/pnas.1917968117.

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Mitochondria have a characteristic ultrastructure with invaginations of the inner membrane called cristae that contain the protein complexes of the oxidative phosphorylation system. How this particular morphology of the respiratory membrane impacts energy conversion is currently unknown. One proposed role of cristae formation is to facilitate the establishment of local proton gradients to fuel ATP synthesis. Here, we determined the local pH values at defined sublocations within mitochondria of respiring yeast cells by fusing a pH-sensitive GFP to proteins residing in different mitochondrial su
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9

Zorkau, Matthew, Christin A. Albus, Rolando Berlinguer-Palmini, Zofia M. A. Chrzanowska-Lightowlers, and Robert N. Lightowlers. "High-resolution imaging reveals compartmentalization of mitochondrial protein synthesis in cultured human cells." Proceedings of the National Academy of Sciences 118, no. 6 (2021): e2008778118. http://dx.doi.org/10.1073/pnas.2008778118.

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Human mitochondria contain their own genome, mitochondrial DNA, that is expressed in the mitochondrial matrix. This genome encodes 13 vital polypeptides that are components of the multisubunit complexes that couple oxidative phosphorylation (OXPHOS). The inner mitochondrial membrane that houses these complexes comprises the inner boundary membrane that runs parallel to the outer membrane, infoldings that form the cristae membranes, and the cristae junctions that separate the two. It is in these cristae membranes that the OXPHOS complexes have been shown to reside in various species. The majori
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10

de L. Fortes, Gerson R., Luciana B. Andrade, Janine T. C. Faria, Marisa de F. Oliveira, and Nilvane T. G. Müller. "In Vitro Multiplication of Potato (Solanum tuberosum L.) cv. Cristal II—Microcutting Origin." HortScience 32, no. 3 (1997): 471F—472. http://dx.doi.org/10.21273/hortsci.32.3.471f.

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The potato cultivar Cristal recently released by the CPACT/EMBRAPA Breeding Program has high dry matter and low reduce sugars. These are desirable characteristics as industry processing is concerned. Nevertheless, this is a recalcitrant cultivar. The meristem culture is difficult to establish along with a very low multiplication rate. The aim of this work was to improve the multiplication rate for this cultivar. Two-bud microcuttings derived from apical, mid, and basal regions were inoculated in test tubes with 10 ml MS culture media and vitamins as follows; myo-inositol (100 mg·L–1); sucrose
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11

Bachiller-Perea, Diana, Yves-Marie Abiven, Jérôme Bisou, et al. "First pump–probe–probe hard X-ray diffraction experiments with a 2D hybrid pixel detector developed at the SOLEIL synchrotron." Journal of Synchrotron Radiation 27, no. 2 (2020): 340–50. http://dx.doi.org/10.1107/s1600577520000612.

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A new photon-counting camera based on hybrid pixel technology has been developed at the SOLEIL synchrotron, making it possible to implement pump–probe–probe hard X-ray diffraction experiments for the first time. This application relies on two specific advantages of the UFXC32k readout chip, namely its high frame rate (50 kHz) and its high linear count rate (2.6 × 106 photons s−1 pixel−1). The project involved the conception and realization of the chips and detector carrier board, the data acquisition system, the server with its specific software, as well as the mechanical and cooling systems.
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12

Bedoya, Julio. "Evolución de la Gammagrafía en el Servicio de Medicina Nuclear de la Facultad de Medicina de la Universidad Nacional Mayor de San Marcos y del Hospital Obrero de Lima." Anales de la Facultad de Medicina 49, no. 4 (2014): 659. http://dx.doi.org/10.15381/anales.v49i4.5605.

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1. El trabajo estudia la evolución, de la Gammagrafía o Scanning, en el Servicio de Medicina Nuclear de la Facultad de Medicina y del Hospital Obrero de Lima, para lo que se señalan, 3 etapas: A. La primera, comprende; desde la primera captación de iodo radioactivo, realizada en Agosto de 1955, hasta la delimitación manual de la tiroides, pasando por la realización de todas las pruebas líquidas realizadas con un detector de centelleo de cristal de pozo; se considera ésta etapa, como un estudio y entrenamiento previo indispensable, para poder trabajar, en forma eficiente, con los equipos e isót
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13

Juric-Lekic, Gordana, Ljiljana Bedrica, and Dragutin Loncar. "Interscapular brown adipose tissue recruitment is hindered by a temperature environment of 33°C: Uncoupling protein-1 underexpression is not associated with obesity development in rats." Archives of Biological Sciences 70, no. 3 (2018): 567–79. http://dx.doi.org/10.2298/abs171215018j.

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Brown adipose tissue (BAT) generates heat due to unique thermogenic UC-mitochondria, an event known as nonshivering thermogenesis. Cold, adrenergic agents, hormones, etc., activate nonshivering thermogenesis, resulting in lipid mobilization, an increase in the mitochondria and mitochondrial cristae, and increased uncoupling protein-1 (UCP1) expression and its incorporation into mitochondrial cristae. BAT precursor cells mature and contribute to BAT growth in a process known as BAT recruitment. For the first time, we herein report the effect of a thermoneutral environment of 33?C on interscapul
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14

Maaswinkel, R. H. M., and G. W. H. Welles. "Factors affecting head formation of iceberg lettuce (Lactuca sativa L.)." Netherlands Journal of Agricultural Science 35, no. 1 (1987): 37–42. http://dx.doi.org/10.18174/njas.v35i1.16756.

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In a series of greenhouse experiments (winter and spring, 1980-85), significant differences in frequency of (undesirable) open head formation were detected among 6 cultivars. Starlina, Aubade, Cristallo and Kellys showed 18-38% open heads, whereas Sonia and Marbello had
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15

Silva, Vanessa Tavares da, Marta Rabello Piva, Liane Maciel de Almeida Souza, Klinger de Souza Amorim, and Francisco Carlos Groppo. "Relação entre presença de fendas de cristais de colesterol em lesão periapical e nível de colesterol sérico." Revista de Odontologia da UNESP 42, no. 2 (2013): 94–98. http://dx.doi.org/10.1590/s1807-25772013000200005.

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INTRODUÇÃO: Uma infecção crônica nos tecidos periapicais pode desencadear uma lesão periapical em função da estimulação e da proliferação dos restos epiteliais de Malassez. Ao estudo microscópico, é possível detectar a presença de fendas de cristais de colesterol no interior de cistos e granulomas. De acordo com alguns estudos, a origem do colesterol no interior de lesões no periápice pode ser, parcialmente, por causa da condensação e da cristalização de colesterol dentro da parede do cisto. Outros estudos afirmam que a presença de colesterol pode ser derivada de produtos metabólicos locais ou
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16

Claypool, Steven M., Pinmanee Boontheung, J. Michael McCaffery, Joseph A. Loo, and Carla M. Koehler. "The Cardiolipin Transacylase, Tafazzin, Associates with Two Distinct Respiratory Components Providing Insight into Barth Syndrome." Molecular Biology of the Cell 19, no. 12 (2008): 5143–55. http://dx.doi.org/10.1091/mbc.e08-09-0896.

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Mutations in the mitochondrial cardiolipin (CL) transacylase, tafazzin (Taz1p), result in the X-linked cardioskeletal myopathy, Barth syndrome (BTHS). The mitochondria of BTHS patients exhibit variable respiratory defects and abnormal cristae ultrastructure. The biochemical basis for these observations is unknown. In the absence of its target phospholipid, CL, a very large Taz1p complex is missing, whereas several discrete smaller complexes are still observed. None of the identified Taz1p complexes represents Taz1p homodimers. Instead, yeast Taz1p physically assembles in several protein comple
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17

Iacono, E., B. Merlo, M. Regazzini, and D. Zambelli. "66 DEVELOPMENT OF IN VITRO-PRODUCED CAT EMBRYOS AFTER VITRIFICATION AND NONSURGICAL EMBRYO TRANSFER: PRELIMINARY RESULTS." Reproduction, Fertility and Development 21, no. 1 (2009): 133. http://dx.doi.org/10.1071/rdv21n1ab66.

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There are no refereed reports on vitrification of domestic cat embryos derived from in vitro-matured oocytes and transferred using a nonsurgical embryo transfer technique. The aim of this study was to verify the effects of vitrification on the in vitro and in vivo developmental ability of in vitro-produced (IVP) cat blastocysts. Oocytes recovered from minced ovaries were matured, fertilized, and cultured in vitro as previously reported (Merlo B et al. 2005 Theriogenology 63, 2032–2039). On Day 7 of in vitro culture (IVC), blastocysts were selected and vitrified in straws (Cristal ET 0.25 mL, 1
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18

Putignani, L., S. Raffa, R. Pescosolido, et al. "Development of phenotypic indexes for the description of morphological injury in breast cancer cell mitochondria." Journal of Clinical Oncology 27, no. 15_suppl (2009): e22055-e22055. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e22055.

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e22055 Background: Mitochondriopathy has been recently rekindled as new cancer theory. We report on structural damage of breast-infiltrating ductal carcinoma (IDC) mitochondria characterised by reduced expression levels of the oxidative phosphorylation system (OXPHOS). Methods: Mitochondria from HMC-1 (human mammary carcinoma) and HMEC (human mammary epithelial cell) cultures, traced by Mitotracker, were assayed for OXPHOS expression levels using cryo-immunoelectron microscopy (CIEM) quantitative labelling and fluorescence immunolabelling on unfractionated HMC-1 and HEMC cells. Convolution deg
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19

Sultemeier, David R., Kristel R. Choy, Felix E. Schweizer, and Larry F. Hoffman. "Spaceflight-induced synaptic modifications within hair cells of the mammalian utricle." Journal of Neurophysiology 117, no. 6 (2017): 2163–78. http://dx.doi.org/10.1152/jn.00240.2016.

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Exposure to the microgravity conditions of spaceflight alleviates the load normally imposed by the Earth’s gravitational field on the inner ear utricular epithelia. Previous ultrastructural investigations have shown that spaceflight induces an increase in synapse density within hair cells of the rat utricle. However, the utricle exhibits broad physiological heterogeneity across different epithelial regions, and it is unknown whether capabilities for synaptic plasticity generalize to hair cells across its topography. To achieve systematic and broader sampling of the epithelium than was previous
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20

Monaghan, P., D. Robertson, T. A. Amos, M. J. Dyer, D. Y. Mason, and M. F. Greaves. "Ultrastructural localization of bcl-2 protein." Journal of Histochemistry & Cytochemistry 40, no. 12 (1992): 1819–25. http://dx.doi.org/10.1177/40.12.1453000.

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Previous cell subfractionation studies have indicated that bcl-2 is an inner mitochondrial membrane protein. We have sought to determine the ultrastructural localization of bcl-2 protein in lymphoma and breast carcinoma cell lines and biopsy material known to overexpress bcl-2 using immunoelectron microscopy. To avoid the possibility of processing artifacts, samples were prepared by three different methods: progressive lowering of temperature, cryosectioning, and freeze-substitution. In all instances the labeling of bcl-2 protein was relatively weak but the distribution the same. In both lymph
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Riskiono, Sampurna Dadi, Roy Harry Syidiq Pamungkas, and Yudha Arya. "RANCANG BANGUN SISTEM PENYIRAMAN TANAMAN SAYUR BERBASIS ARDUINO DENGAN SENSOR KELEMBABAN TANAH." Jurnal Ilmiah Mahasiswa Kendali dan Listrik 1, no. 1 (2020): 23–32. http://dx.doi.org/10.33365/jimel.v1i1.186.

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Development at this time is increasing, people expect a tool or technology that can help human work, so technology becomes a necessity for humans. This final task is made a device that can do the job of watering tomato plants automatically. This tool aims to replace the manual work becomes automatic. The benefit of this tool is that it can facilitate the work of humans in watering chili plants. This tool uses a soil moisture sensor which acts as a soil moisture detector and sends an order to Arduino Uno to turn on the relay driver so that the wiper motor can splash water according to the needs
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22

Slavik, E., D. Radulovic, and G. Tasic. "Olfactory groove maningiomas." Acta chirurgica Iugoslavica 54, no. 2 (2007): 59–62. http://dx.doi.org/10.2298/aci0702059s.

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Meningiomas, usually histologically benign tumors, are originating from the arachnoidal cap cells normally present intracranially in varying sites. Olfactory groove meningeomas arise from the medline of the anterior fossa between the crista galli and the tuberculum sellae. The most common presenting symptoms are the visual field defects, epilepsy, and psychological change. They are often large before they are detected because of slowly asymptomatic growing in the interhemispheric space of the frontal lobes. This series is consisted of 29 patients suffering from olfactory groove meningiomas tre
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23

Bauwens, Louis J. J. M., John C. M. J. De Groot, Jan E. Veldman, Frans C. S. Ramaekers, and Egbert H. Huizing. "Expression of Intermediate Filament Proteins in the Adult Human Vestibular Labyrinth." Annals of Otology, Rhinology & Laryngology 101, no. 6 (1992): 479–86. http://dx.doi.org/10.1177/000348949210100606.

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The immunohistochemical detection of intermediate filament proteins, cytoskeletal constituents that allow the characterization of tissues, was investigated in frozen sections of the chemically fixed, nondecalcified, adult human vestibular labyrinth. Cytokeratins (CKs) were detected in all epithelia (including the sensory epithelia), although substantial differences in the degree of staining between individual cells occurred. The expression of CKs 7, 8, 18, and 19 as detected with our subunit-specific monoclonal antibodies in the vestibular epithelia is typical of “simple” epithelia and is iden
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24

Dunham, Michael E., and Robert P. Miller. "Bilateral Choanal Atresia Associated with Malformation of the Anterior Skull Base: Embryogenesis and Clinical Implications." Annals of Otology, Rhinology & Laryngology 101, no. 11 (1992): 916–19. http://dx.doi.org/10.1177/000348949210101106.

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A number of craniofacial and systemic malformations have been described in association with choanal atresia. We report a case of bilateral choanal atresia associated with congenital absence of the cribriform plate, crista galli, and perpendicular plate of the ethmoid bone. The anterior skull base defect was detected by using high-resolution computed tomography with three-dimensional reconstructions. The findings support the mesodermal flow theory of choanal atresia, in which there is excess migration of neural crest cells into the developing nasal septum and posterior choanae. This occurs at t
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25

Singh, R., G. Upadhyay, and MM Godbole. "Hypothyroidism alters mitochondrial morphology and induces release of apoptogenic proteins during rat cerebellar development." Journal of Endocrinology 176, no. 3 (2003): 321–29. http://dx.doi.org/10.1677/joe.0.1760321.

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Thyroid hormone (TH) deficiency leads to extensive apoptosis during cerebellar development, but the mechanism still remains unclear. Different signals also converge on mitochondria during apoptosis to induce the release of apoptogenic proteins that activate proteolytic cascade through specific enzymes called caspases. Here we studied the effect of hypothyroidism on alterations in mitochondrial structure and translocation of apoptogenic molecules during rat cerebellar development. Structural analysis of mitochondria was studied by electron microscopy. The translocation of apoptogenic molecules
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26

Sujiwa, Akbar, and Oktavianus Hadiwikarta. "ARDUINO UNO BASED AUTOMATIC DESIGN TO BUILD WINE DRINKING TOOL USING SOIL MOISTURE SENSOR." BEST : Journal of Applied Electrical, Science, & Technology 2, no. 2 (2020): 24–27. http://dx.doi.org/10.36456/best.vol2.no2.3468.

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The development in this era is increasing, humans expect a tool or technology that can help human work, because now technology has become a human need. Therefore, a device that can do watering the wine is made automatically. This tool aims to replace manual work to be automatic. The benefits that can be obtained from this tool is that it can facilitate human work in watering grapes. This tool uses a soil moisture sensor which functions as a soil moisture detector and sends commands to Arduino uno to turn on the relay driver so that the pump can flush water according to soil needs automatically
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27

Ivana, Čabarkapa, Škrinjar Marija, Lević Jovanka, et al. "Biofilm Forming Ability Of Salmonella Enteritidis In Vitro." Acta Veterinaria 65, no. 3 (2015): 371–89. http://dx.doi.org/10.1515/acve-2015-0031.

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AbstractSalmonella entericaserotype Enteritidis is an important alimentary pathogen that recently gained special attention due to the ability of a large number of strains to form biofilms. Qualitative testing of biofilm forming ability was performed by observing the morphotype of the colonies on Congo Red agar and by conducting the pellicle test, while quantitative testing was carried out by Cristal violet assay on microtiter plates. A total of 14 isolates of S. Enteritidis were tested for biofilm forming ability, while Salmonella Enteritidis ATTC 13076 was used as the reference strain. Based
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Salles, Luiz Antonio. "Incidência de danos de Diabrotica speciosa em cultivares e linhagens de batata." Ciência Rural 30, no. 2 (2000): 205–9. http://dx.doi.org/10.1590/s0103-84782000000200002.

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A cultura da batata é atacada por diversas pragas subterrâneas, sendo que a principal é a vaquinha, Diabrotica speciosa (Col. Chrysomelidae). O objetivo deste trabalho foi o de estudar a incidência de larvas de D. speciosa em tubérculos de cultivares e linhagens de batata para consumo de mesa e de indústria. Foram conduzidos dois experimentos: um com a exclusão total de qualquer outra praga que não a vaquinha e outro em condições naturais de lavoura. No primeiro, as cultivares de batata foram plantadas em solo intensamente hortado e sob gaiolas teladas (confinamento). O segundo, foi desenvolvi
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29

Jing, Guangping, Jinhua Zheng, Xueyong Wang, Haixia Li, and Xiaohui Jiao. "Scutellarein ameliorates tongue cancer cells via mitochondria." Open Medicine 9, no. 2 (2014): 193–99. http://dx.doi.org/10.2478/s11536-013-0269-z.

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AbstractTo investigate the mechanism in Scutellarein-induced apoptosis of SAS human tongue cancer cells, inhibitory effects of Scutellarein on SAS cells were detected by MTT assay. Cell apoptosis was analyzed by flow cytometry. Ultrastructural changes of SAS cells were observed by transmission electron microscopy (TEM). Mitochondrial transmembrane potential (ΔΨm) were analyzed by JC-1 [5,5,6,6-Tetrachloro-1,1,3,3-tetraethylbenzimidazolylcarbocyanine iodide]. Western blotting was used to examine the expression level of Bcl-2, Bax and caspase-3 in SAS cells treated with Scutellarein. Scutellarei
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30

Muchtar, Husnibes, and Ridwan Sobirin. "Rancang Bangun Alat Pendeteksi Medan Listrik Portable untuk Keamanan Manusia." RESISTOR (Elektronika Kendali Telekomunikasi Tenaga Listrik Komputer) 4, no. 1 (2021): 47. http://dx.doi.org/10.24853/resistor.4.1.47-54.

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Medan listrik yang ditimbulkan oleh peralatan listrik memiliki dampak buruk bagi manusia, medan listrik tidak dapat dilihat dengan mata manusia namun dampaknya dapat dirasakan oleh tubuh manusia, untuk mengetahui adanya medan listrik dan jarak terjauh medan listrik pada suatu peralatan listrik, maka diperlukan alat pendeteksi medan listrik. Metode yang digunakan Pada proyek akhir ini adalah menggunakan IC CMOS CD 4093 dan sistem mikrokontroller AtMega 328 P. Adapun langkah-langkah yang digunakan yaitu identifikasi kebutuhan alat, perancangan perangkat keras, perancangan perangkat lunak, dan pe
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Macchi, Carlo, Piera Rebuffat, Stella Blandamura, et al. "Adrenocortical Oncocytoma: Case Report and Review of the Literature." Tumori Journal 84, no. 3 (1998): 403–7. http://dx.doi.org/10.1177/030089169808400318.

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Only 9 oncocytic neoplasms of true adrenal origin have been described to date. It therefore seemed of interest to study the histochemical and ultrastructural features of a non-functioning monolateral adrenocortical oncocytoma which was incidentally detected by ultrasonography and magnetic resonance imaging in a 28-year-old woman. The tumor was round, well encapsulated and weighed 73 g. It consisted of islets of eosinophilic cells, and did not display any sign of necrosis. The proliferation rate (as evaluated by mitotic index and percentage of MIB-1 Ki67 positive cells) was low, and atypic mito
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32

Sayed, Ramy K. A., Marisol Fernández-Ortiz, María E. Diaz-Casado, et al. "Lack of NLRP3 Inflammasome Activation Reduces Age-Dependent Sarcopenia and Mitochondrial Dysfunction, Favoring the Prophylactic Effect of Melatonin." Journals of Gerontology: Series A 74, no. 11 (2019): 1699–708. http://dx.doi.org/10.1093/gerona/glz079.

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Abstract To investigate the role of NLRP3 inflammasome in muscular aging, we evaluated here the morphological and functional markers of sarcopenia in the NLRP3-knockout mice, as well as the beneficial effect of melatonin supplementation. The gastrocnemius muscles of young (3 months), early-aged (12 months), and old-aged (24 months) NLRP3-knockout female mice were examined. Moreover, locomotor activity and apoptosis were assessed. The results revealed early markers of sarcopenia at the age of 12 months, including reduction of lactate, ratio of muscle weight to body weight, muscle fibers number,
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Fik, V. B., Ye V. Paltov, and Yu Ya Kryvko. "Electronic microscopic research on periodont in experimental two-weight opioid action and after its over for four weeks." Reports of Morphology 25, no. 3 (2019): 27–32. http://dx.doi.org/10.31393/morphology-journal-2019-25(3)-05.

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Due to the harmful effects of opioid agents in the uncontrolled use of them, it is impossible to ease the early manifestations of damage to the tissues and organs of the oral cavity, which is a pressing problem of today. The purpose of this work was to investigate the features of the sub-microscopic organization of the structural components of the periodontium under the action of an opioid analgesic for two weeks and its four-week withdrawal in the experiment. The study was conducted on 22 adult rats-males of the Wistar line, weighing 160 g, 4.5-6 months of age. Animals were administered intra
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Lipscomb, T. P., M. G. Mense, P. L. Habecker, J. K. Taubenberger, and R. Schoelkopf. "Morbilliviral Dermatitis in Seals." Veterinary Pathology 38, no. 6 (2001): 724–26. http://dx.doi.org/10.1354/vp.38-6-724.

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A juvenile female hooded seal ( Cystophora cristata) and a juvenile male harp seal ( Phoca groenlandica) stranded separately on the New Jersey (USA) coast and were taken to a marine mammal rehabilitation center. Both were lethargic and emaciated, had dermatitis, and died. Histologic skin lesions in the seals were similar and consisted of epidermal and follicular epithelial hyperplasia, hyperkeratosis, degeneration, and necrosis. The most distinctive finding was extensive syncytial zones bounded superficially by hyperkeratosis and deeply by hyperplastic basal cells. Eosinophilic intracytoplasmi
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Shalaby, Amany Mohamed, Adel Mohamed Aboregela, Mohamed Ali Alabiad, and Dina Fouad El Shaer. "Tramadol Promotes Oxidative Stress, Fibrosis, Apoptosis, Ultrastructural and Biochemical alterations in the Adrenal Cortex of Adult Male Rat with Possible Reversibility after Withdrawal." Microscopy and Microanalysis 26, no. 3 (2020): 509–23. http://dx.doi.org/10.1017/s1431927620001397.

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AbstractTramadol is a centrally acting analgesic drug, used for the management of moderate to severe pain in a variety of diseases. The long-term use of tramadol can induce endocrinopathy. This study aimed to evaluate the effect of tramadol dependence on the adrenal cortex and the effect of its withdrawal. Thirty adult male rats were divided into three experimental groups: the control group, the tramadol-dependent group that received increasing therapeutic doses of tramadol orally for 1 month, and the recovery group that received tramadol in a dose and duration similar to the previous group fo
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36

Cousin, B., S. Cinti, M. Morroni, et al. "Occurrence of brown adipocytes in rat white adipose tissue: molecular and morphological characterization." Journal of Cell Science 103, no. 4 (1992): 931–42. http://dx.doi.org/10.1242/jcs.103.4.931.

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Brown adipocytes are thermogenic cells which play an important role in energy balance. Their thermogenic activity is due to the presence of a mitochondrial uncoupling protein (UCP). Until recently, it was admitted that in rodents brown adipocytes were mainly located in classical brown adipose tissue (BAT). In the present study, we have investigated the presence of UCP protein or mRNA in white adipose tissue (WAT) of rats. Using polymerase chain reaction or Northern blot hybridization, UCP mRNA was detected in mesenteric, epidydimal, retroperitoneal, inguinal and particularly in periovarian adi
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Vázquez-Medina, J. P., N. O. Olguín-Monroy, P. D. Maldonado, et al. "Maturation increases superoxide radical production without increasing oxidative damage in the skeletal muscle of hooded seals (Cystophora cristata)." Canadian Journal of Zoology 89, no. 3 (2011): 206–12. http://dx.doi.org/10.1139/z10-107.

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Diving vertebrates represent unique models for the study of the physiological responses to reactive oxygen species (ROS) production and oxidative stress because of their adaptability to cope with dive-derived ROS production. We hypothesized that in the skeletal muscle of a diving mammal, the hooded seal ( Cystophora cristata (Erxleben, 1777)), ROS production increases with maturation but the accumulation of oxidative damage does not. To test this, we analyzed the tissue capacity to produce ROS, the accumulation of oxidative damage, and the activity and protein content of the cooper, zinc, and
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Wang, Fengyue, Jing Yang, Junfeng Sun, et al. "Testosterone replacement attenuates mitochondrial damage in a rat model of myocardial infarction." Journal of Endocrinology 225, no. 2 (2015): 101–11. http://dx.doi.org/10.1530/joe-14-0638.

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Testosterone can affect cardiovascular disease, but its effects on mitochondrial dynamics in the post-infarct myocardium remain unclear. To observe the effects of testosterone replacement, a rat model of castration-myocardial infarction (MI) was established by ligating the left anterior descending coronary artery 2 weeks after castration with or without testosterone treatment. Expression of mitochondrial fission and fusion proteins was detected by western blot and immunofluorescence 14 days after MI. Cardiac function, myocardial inflammatory infiltration and fibrosis, cardiomyocyte apoptosis,
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Ge, Junhua, Haichu Yu, Jian Li, et al. "Assessment of aflatoxin B1 myocardial toxicity in rats: mitochondrial damage and cellular apoptosis in cardiomyocytes induced by aflatoxin B1." Journal of International Medical Research 45, no. 3 (2017): 1015–23. http://dx.doi.org/10.1177/0300060517706579.

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Objective The number of deaths from heart disease is increasing worldwide. Aflatoxin B1 (AFB1), a toxin produced by the fungi Aspergillus flavus and Aspergillus parasiticus, is frequently detected in improperly processed/stored human food products. While AFB1 hepatotoxicity and carcinogenic properties have been well addressed, its myocardial toxicity is poorly documented. This study aimed to investigate myocardial toxic activity of AFB1. Methods Ten rats were fed with AFB1 at a dose that did not result in acute toxic reactions for 30 days and 10 vehicle-fed rats served as controls. Transmissio
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Tanne, E., L. Kuznetsova, J. Cohen, S. Alexandrova, and A. Gera. "Phytoplasmas as Causal Agents of Celosia Disease in Israel." HortScience 35, no. 6 (2000): 1103–6. http://dx.doi.org/10.21273/hortsci.35.6.1103.

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Recently, yellows diseases have become more common in Israel, and phytoplasmas have been detected in some of these diseased crops. Commercial fields of two celosia species (Celosia plumosa L. and C. cristata L.) also have exhibited yellows symptoms and total crop failure. Typical mycoplasma-like bodies were observed in infected but not in healthy plants. The same plants were analyzed for the presence of phytoplasma by polymerase chain reaction (PCR), using the universal oligonucleotide pair r16SF2/r16SR2, followed by nested PCR using group-specific primers. Restriction analyses performed with
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Aznar, Francisco Javier, José Monterde-López, Samuel Aunión-Díaz, Harry J. Lehto, and Elena Circella. "First evidence of avian pox-like outbreaks in Eurasian coots, Fulica atra, from Europe: A widespread phenomenon?" Avian Biology Research 12, no. 4 (2019): 139–44. http://dx.doi.org/10.1177/1758155919860349.

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Avian pox is a disease caused by Avipoxvirus spp. that is known to produce self-limiting, proliferative epithelial lesions in over 275 bird species from 70 families. Although generally benign, this emerging disease can sometimes provoke significant outbreaks of mortality. In rallids, there is a single serological record of Avipoxvirus. In this study, we report on field evidence for two avian pox-like outbreaks in Eurasian coots, Fulica atra. In Utterslev Mose, Denmark, 17 birds were found in the winter and early spring of 2006 with putative signs of pox-like lesions on the frontal shield and b
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Yang, Shi-kun, Ai-mei Li, Ya-chun Han, et al. "Mitochondria-Targeted Peptide SS31 Attenuates Renal Tubulointerstitial Injury via Inhibiting Mitochondrial Fission in Diabetic Mice." Oxidative Medicine and Cellular Longevity 2019 (June 2, 2019): 1–13. http://dx.doi.org/10.1155/2019/2346580.

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Objective. Renal tubular injury is an early characteristic of diabetic nephropathy (DN) that is related to mitochondrial dysfunction. In this study, we explore the effects and mechanisms of mitochondria-targeted peptide SS31 on renal tubulointerstitial injury in DN. Method. 40 C57BL/6 mice were randomly divided into control group, STZ group, STZ+SS31 group, and STZ+normal saline group. SS31 was intraperitoneally injected to the mice every other day for 24 weeks. Renal lesions and the expression of Drp1, Mfn1, Bcl-2, Bax, Caspase1, IL-1β, and FN were detected. In in vitro studies, HK-2 cells we
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Sayed, Ramy K. A., Marisol Fernández-Ortiz, Ibtissem Rahim, et al. "The Impact of Melatonin Supplementation and NLRP3 Inflammasome Deletion on Age-Accompanied Cardiac Damage." Antioxidants 10, no. 8 (2021): 1269. http://dx.doi.org/10.3390/antiox10081269.

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To investigate the role of NLRP3 inflammasome in cardiac aging, we evaluate here morphological and ultrastructural age-related changes of cardiac muscles fibers in wild-type and NLRP3-knockout mice, as well as studying the beneficial effect of melatonin therapy. The results clarified the beginning of the cardiac sarcopenia at the age of 12 months, with hypertrophy of cardiac myocytes, increased expression of β-MHC, appearance of small necrotic fibers, decline of cadiomyocyte number, destruction of mitochondrial cristae, appearance of small-sized residual bodies, and increased apoptotic nuclei
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44

Pimenta, Tania A., Ivana M. N. Victoria, Eduardo A. Bambirra, et al. "Paraganglioma funcionante do pescoço." Arquivos Brasileiros de Endocrinologia & Metabologia 42, no. 6 (1998): 478–82. http://dx.doi.org/10.1590/s0004-27301998000600010.

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Paragangliomas funcionantes são tumores raros, produtores de catecolaminas que se originam da crista neural. Apresentamos o caso de um paciente de 11 anos com quadro de hipertensão arterial grave e massa em região cervical direita. Apresentou aumento das catecolaminas e metabólitos urinários: epinefrina, 97,8 mg/24hs (Valor de Referência (VR)= 0,5 a 20); norepinefrina, 184,8 mg/24hs (VR= 15 a 80); dopamina, 513,5 mg/24hs (VR= 65 a 400); metanefrina, 0,08 mg/g de creatinina (VR< 0,31); normetanefrina, 0,64 mg/g de creatinina (VR< 0,43); ácido vanilmandélico, 69,3 mmol/24hs (VR= 10 a 35).
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45

Paukov, V. S., Yu A. Kirillov, Yu A. Erokhin, and I. A. Chernov. "Cardiac and vascular changes in the patho- and morphogenesis of alcohol use disorder." Cardiovascular Therapy and Prevention 19, no. 5 (2020): 2436. http://dx.doi.org/10.15829/1728-8800-2020-2436.

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Aim. To reveal the patho- and morphogenesis of microvascular injury, cardiac and vascular changes in individuals with alcohol use disorder (AUD) and the role of cardiovascular pathology in the thanatogenesis of patients with chronic alcohol intoxication.Material and methods. The study was carried out using the data of 1118 autopsies of patients with AUD. We used histological, immuno-histochemical, electron microscopic and biochemical methods, as well as morphometrics with statistical processing of the results.Results. Most patients with binge drinking developed alcoholic cardiomyopathy, cardia
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Brajuskovic, Goran, Andjelija Skaro-Milic, Slobodan Marjanovic, Snezana Cerovic, and Slavica Knezevic-Usaj. "The ultrastructural investigation of mitochondria in B-CLL cells during apoptosis." Archive of Oncology 12, no. 3 (2004): 139–41. http://dx.doi.org/10.2298/aoo0403139b.

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BACKGROUND: B-chronic lymphocytic leukemia (B-CLL) is an example of human malignancy caused by alternations in the pathways of apoptosis. Mitochondria play a critical role in the regulation of this process. The B-CLL cells dying in apoptosis showed typical morphological characteristics: the reduction of the nuclear volume is accompanied with the reduction of the cytoplasmatic volume, while many of organelles remain intact. The aim of our study was ultrastructural investigation of mitochondrial morphology in apoptotic B- CLL cells. METHODS: Our study included peripheral blood samples from 32 B-
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Palomäki, V., and T. Holopainen. "Effects of phosphorus deficiency and recovery fertilization on growth, mineral concentration, and ultrastructure of Scots pine needles." Canadian Journal of Forest Research 24, no. 12 (1994): 2459–68. http://dx.doi.org/10.1139/x94-317.

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During the first year of a 2-year field experiment (1989–1990), 3-year-old Scots pine (Pinussylvestris L.) seedlings were watered with phosphorus-deficient nutrient solutions containing no phosphorus (0%) or 30% of the optimal phosphorus supply. A complete nutrient solution was used as the control. In the second growing period, the seedlings were divided into two groups, a deficiency and a recovery treatment, to follow the further development of, and recovery from, symptoms. Phosphorus contents in both current- and previous-year needles in both deficiency groups decreased clearly during the fi
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48

Pelletier, G., S. Li, V. Luu-The, Y. Tremblay, A. Belanger, and F. Labrie. "Immunoelectron microscopic localization of three key steroidogenic enzymes (cytochrome P450(scc), 3 beta-hydroxysteroid dehydrogenase and cytochrome P450(c17)) in rat adrenal cortex and gonads." Journal of Endocrinology 171, no. 2 (2001): 373–83. http://dx.doi.org/10.1677/joe.0.1710373.

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The biosynthesis of steroid hormones in endocrine steroid-secreting glands results from a series of successive steps involving both cytochrome P450 enzymes, which are mixed-function oxidases, and steroid dehydrogenases. So far, the subcellular distribution of steroidogenic enzymes has been mostly studied following subcellular fractionation, performed in placenta and adrenal cortex. In order to determine in situ the intracellular distribution of some steroidogenic enzymes, we have investigated the ultrastructural localization of the three key enzymes: P450 side chain cleavage (scc) which conver
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Mercado, Francisco, Iván A. López, Dora Acuna, Rosario Vega, and Enrique Soto. "Acid-Sensing Ionic Channels in the Rat Vestibular Endorgans and Ganglia." Journal of Neurophysiology 96, no. 3 (2006): 1615–24. http://dx.doi.org/10.1152/jn.00378.2006.

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Acid-sensing ionic channels (ASICs) are members of the epithelial Na+ channel/degenerin (ENaC/DEG) superfamily. ASICs are widely distributed in the central and peripheral nervous system. They have been implicated in synaptic transmission, pain perception, and the mechanoreception in peripheral tissues. Our objective was to characterize proton-gated currents mediated by ASICs and to determine their immunolocation in the rat vestibular periphery. Voltage clamp of cultured afferent neurons from P7 to P10 rats showed a proton-gated current with rapid activation and complete desensitization, which
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Rodrigue-Way, Amélie, Annie Demers, Huy Ong, and André Tremblay. "A Growth Hormone-Releasing Peptide Promotes Mitochondrial Biogenesis and a Fat Burning-Like Phenotype through Scavenger Receptor CD36 in White Adipocytes." Endocrinology 148, no. 3 (2007): 1009–18. http://dx.doi.org/10.1210/en.2006-0975.

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Whereas the uptake of oxidized lipoproteins by scavenger receptor CD36 in macrophages has been associated with foam cell formation and atherogenesis, little is known about the role of CD36 in regulating lipid metabolism in adipocytes. Here we report that treatment of 3T3-L1 adipocytes with hexarelin, a GH-releasing peptide that interacts with CD36, resulted in a depletion of intracellular lipid content with no significant change in CD36 expression. Microarray analysis revealed an increased pattern in several genes involved in fatty acid mobilization toward the mitochondrial oxidative phosphory
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