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1

MJ, Akhildev, Albin Saj Chalissery, Maritta Stephen, and Deepa Devassy. "Fusion Reality." International Journal of Innovative Science and Research Technology 5, no. 6 (July 12, 2020): 1278–90. http://dx.doi.org/10.38124/ijisrt20jun1127.

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Fusion Reality is the next generation reality that will change the aspect of everything. We talk about a lot of reality technologies including augmented reality and virtual reality. But experiencing mixed reality is really expensive. This paper deals with fusion reality which aims to develop a software development kit that includes support for developing mixed reality applications within minutes. Our development kit is included in the official website of our fusion reality. Developers can download and install the Unity 3D software. After downloading the software developers can import the fusion reality kit package which is available at our website and can start to create theirs on mixed reality applications. The website contains the necessary files for developing fusion reality applications as well as integrated with an artificially intelligent chatbot which can be helpful in solving any doubts and queries the developers might have while developing the application. The chatbot is also available on telegram social media applications and developers can utilize the telegram application also to solve doubts and queries. Atoms, CoronaAR are android applications developed with a fusion reality kit of ours. Atoms deal with chemistry and aim to decrease the complexity of learning periodic table and other chemistry related things. CoronaAR also built with the latest technologies and tools associated with the fusion reality SDK and assets. Atoms are capable of augmenting the periodic table and elements with details of each particular element having its basic properties with isotopes, compounds and video displays to learn or experience periodic table like never before
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Agarwal, Bhuvan, Soumyajeet Bhattacharjee, Sima Kar, Madhurima Saha, Vijay Kumar, Sandip Mandal, and UEM Kolkata. "An API in JAVA Which Render Ease at Programming for Developers." American Journal of Electronics & Communication 1, no. 4 (June 7, 2021): 27–31. http://dx.doi.org/10.15864/ajec.1405.

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Abstract – Based on the concept of Application programming interface (API).This project comprises of a package named "algokit" which contains several algorithms based on the category of searching, sorting, dynamic programming, tree traversals and swapping. Keeping in mind that different algorithms from the same category have its own benefit in time and space complexity, This project covers almost all the algorithms known and available from each category. This would give the user several options to choose the right algorithm for its code.An user just requires to import the package named AlgoKit and call the functions inside it for a smooth programming experience. One of the prime objectives of this project is to build a kit that serves the purpose of reducing the number of lines of code and also reduce the time taken to run the same code elsewhere. It is platform independent and can be used in any open source Java development environment.
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Tayebi, Maziyar, Afrouzossadat Hosseini Abari, Giti Emtiazi, Byung Gee Kim, and Junehyung Kim. "Novel Bacillus subtilis Spore-Displayed Tyrosinase Kit for Rapid Detection of Tyrosine in Urine: Pharmaceutical Applications for the Early Diagnosis of Kidney-Related Diseases." Advanced Pharmaceutical Bulletin 9, no. 2 (June 1, 2019): 331–34. http://dx.doi.org/10.15171/apb.2019.040.

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Purpose: Simple and cheap diagnostic kit development is one of the important aims of pharmaceutical developers and companies focused on public health improvement. The Bacillus subtilis spore surface-display technique is a genetic engineering method that is used to develop new-generation diagnostic kits applicable for the early detection of various types of diseases. In this study, we developed a novel simple, rapid, and inexpensive diagnostic paper-based kit to detect tyrosine in urine samples of humans and animals that is applicable for home or laboratory use. Methods: The B. subtilis spore-displayed tyrosinase system developed by genetic engineering methods was used to prepare a paper-based kit to detect tyrosine in urine samples of different groups of patients (i.e., patients with diabetes, diabetes with chronic kidney disease (CKD), and chronic kidney disease) for the detection of tyrosine during the acute disease phase. To confirm the sensitivity and specificity of the kit, tyrosine was also detected in urine samples using conventional liquid chromatography/mass spectroscopy. Results: Different concentrations of tyrosine (0.1–1 mM) were detected in urine samples based on visible changes of color from bright brownish-gray to dark brownish-gray within 1 hour. The kit could screen samples to distinguish the three groups of patients based on formation of a broad spectrum of colors reflecting the concentration of tyrosine. Conclusion: To the best of our knowledge, this is the first diagnostic kit with potential to rapidly diagnose various diseases related to the production of tyrosine in biological samples. This kit is not only widely applicable, including for personal use in the home, but is also appropriate as a part of standard screening tests and health protection programs in countries with limited resources.
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Dellen, Barbara, Frank Maurer, Jürgen Münch, and Martin Verlage. "Enriching Software Process Support by Knowledge-Based Techniques." International Journal of Software Engineering and Knowledge Engineering 07, no. 02 (June 1997): 185–215. http://dx.doi.org/10.1142/s0218194097000102.

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Representations of activities dealing with the development or maintenance of software are called software process models. Process models allow for communication, reasoning, guidance, improvement, and automation. Two approaches for modeling processes and instantiating and managing the process models, namely CoMo-Kit and MVP-E, are combined to build a more powerful one. CoMo-Kit is based on AI/KE technology; it is a support tool system for general complex design processes, and was not been developed specifically with software development processes in mind. MVP-E is a process-sensitive software engineering environment for modeling and analyzing software development processes, and guides software developers. Additionally, it provides services to establish and run measurement programmes in software organizations. Because both approaches were developed independently from one another, major integration efforts had to be made to combine both their advantages. This article concentrates on the resulting language concepts, and their operationalization necessary for building automated process support.
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Afif, Rizka Lukmana, Kodrat Iman Satoto, and Kurniawan Teguh Martono. "Perancangan PC Game First Person Shooter Menggunakan Unreal Development Kit." Jurnal Teknologi dan Sistem Komputer 2, no. 2 (April 30, 2014): 149–56. http://dx.doi.org/10.14710/jtsiskom.2.2.2014.149-156.

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The development of hardware increasing rapidly has made game developers take advantage of a variety of new resources that can improve their games. Epic games is a mature game developer who managed to make thousands game and delivered to the hands of gamers . A game engine called Unreal Engine is a big secret behind the success of Epic Games . The game engine is free if you just want to learn or just want to create a personal project and the game is not to be in comercial purposes . It is unfortunate that many students don’t even know of the existence of unreal engine , most of them make use of simpler game engine like game maker , rpg maker , fps creator , and so on. Though unreal engine is superior in any aspect other than the game engine , be it graphics , tools , mechanisms of development , flexible in export-import assets , etc . Based on this information , the author had the idea to make a first person shooter game using the unreal engine as the engine game. Before doing the develpment process, the next step is studying the literature of unreal engine and other supporting software such as 3d studio max to create 3D assets , adobe flash to create the menus , adobe photoshop to create a 2D texture and speedtree assets to create the foliage elements . The next thing is to go into the design phase of scenarios , maps, missions , characters and items that will be placed in the game. The next stage is the development and testing phase to test the game that has finished .The results of the design of this game is the realization of a first person shooter game application using unreal engine with features that can support the player 's interest in playing the game . It’s also introducing unreal engine to students who are interested in designing games.
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Said, Khadija, Zaydah R. de Laurent, Donwilliams O. Omuoyo, Clement Lewa, Elijah Gicheru, Robinson Cheruiyot, Brian Bartilol, et al. "An optimisation of four SARS-CoV-2 qRT-PCR assays in a Kenyan laboratory to support the national COVID-19 rapid response teams." Wellcome Open Research 5 (July 7, 2020): 162. http://dx.doi.org/10.12688/wellcomeopenres.16063.1.

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Background: The global COVID-19 outbreak relies on a quantitative real-time polymerase chain reaction (qRT-PCR) for the detection of severe acute respiratory syndrome coronavirus (SARS-CoV-2), to facilitate the roll-out of patient care and infection control measures. There are several qRT-PCR assays with little evidence on their comparability. We report alterations to the developers’ recommendations to sustain the testing capability in our setting, where the supply of testing reagents is limited. Methods: Standards generated from a serially-diluted positive control and previously identified positive/negative samples were used to determine the optimal volumes of the qRT-PCR reagents and to evaluate the validity and performance of four assays: Charité Berlin and European Virus Archive – GLOBAL (EVAg) primer-probe sets, and DAAN and Beijing Genomics Institute (BGI) premixed commercial kits. A multiplex and singleplex RT-PCR kit was used with the two primer-probe sets and the recommended assay volumes of the two premixed kits were altered. Results: In comparison to the multiplex RT-PCR kit, the singleplex RT-PCR kit combined with the primer-probe sets yielded consistent cycle threshold (Ct) values across the different titrations tested. The DAAN premixed kit produced comparable Ct values across the titrations, while the BGI kit showed incomparable Ct values and inconsistent results between batches using the manufacturer’s recommended volumes. Conclusion: We achieved a 2.5-fold and 4-fold increase in the number of tests/kit for the premixed kits and the primer-probe sets, respectively. The primer-probe set assays were reliable and consistent, and we preferred a combination of an EVAg and a Berlin target. Any inconclusive result was repeated by different individuals following the same protocol. DAAN was a consistent and reliable assay even at lower concentrations from the stated recommendations. BGI in contrast, required dilution to improve its performance and was hence an assay that was used in combination with EVAg or Berlin targets.
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Wattrus, Camilla, Jorge Zepeda, Ruth Vania Cornick, Ronaldo Zonta, Matheus Pacheco de Andrade, Lara Fairall, Daniella Georgeu-Pepper, et al. "Using a mentorship model to localise the Practical Approach to Care Kit (PACK): from South Africa to Brazil." BMJ Global Health 3, Suppl 5 (October 2018): e001016. http://dx.doi.org/10.1136/bmjgh-2018-001016.

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Brazil’s Sistema Único de Saúde, or Unified Health System policy, has delivered major improvements in health coverage and outcomes, but challenges remain, including the rise of non-communicable diseases (NCDs) and variations in quality of care across the country. Some of these challenges may be met through the adaptation and implementation of a South African primary care strategy, the Practical Approach to Care Kit (PACK). Developed by the University of Cape Town’s Knowledge Translation Unit (KTU), PACK is intended for in-country adaptation by employing a mentorship model. Using this approach, the PACK Adult guide and training materials were localised for use in Florianópolis, Santa Catarina, Brazil, as part of an initiative to reform primary care, expand care for NCDs and make services more accessible and equitable. The value of the collaboration between the KTU and Florianópolis municipality is the transfer of skills and avoidance of duplication of effort involved in de-novo guide development, while ensuring that materials are locally acceptable and applicable. The collaboration has informed the development of the KTU’s PACK mentorship package and led to a relationship between the groups of developers, ensuring ongoing learning and research, with the potential of assisting the further scale-up of PACK in Brazil.
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Jiang, Xiao Yan, Hai Ying Wan, and Jian Guo Wang. "Software Development of Large-Span Structure Hoisting on the Time-Varying Analysis." Applied Mechanics and Materials 99-100 (September 2011): 1269–73. http://dx.doi.org/10.4028/www.scientific.net/amm.99-100.1269.

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According to the time-varying analysis theory of large-span structure hoisting, the structure transformation matrix around three-dimensional translation and rotation is obtained. Based on the obtained transformation matrix, the final state matrix after structure hoisting can be described, and the structural internal force of any position can be calculated. Using the Coin3d Open Inventor that is an open source graphics development kit, developers exploited simulation software of large-span structure hoisting. The software can analyze structural security with the time-varying analysis theory, and it has been applied in the simulation of hoisting construction at the Hefei Xinqiao international airport. The results indicated the software is reliable to protect safety of structure hoisting.
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Khan, Muhammad Umair, Scott Uk-Jin Lee, Zhiqiang Wu, and Shanza Abbas. "Wake Lock Leak Detection in Android Apps Using Multi-Layer Perceptron." Electronics 10, no. 18 (September 9, 2021): 2211. http://dx.doi.org/10.3390/electronics10182211.

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With the proliferation of mobile devices, the popularity of Android applications (apps) has increased exponentially. Efficient power consumption in a device is essential from the perspective of the user because users want their devices to work all day. Developers must properly utilize the application programming interfaces (APIs) provided by Android software development kit to optimize the power consumption of their app. Occasionally, developers fail to relinquish the resources required by their app, resulting in a resource leak. Wake lock APIs are used in apps to manage the power state of the Android smartphone, and they frequently consume more power than necessary if not used appropriately (also called energy leak). In this study, we use a multi-layer perceptron (MLP) to detect wake lock leaks in Android apps because the MLP can solve complex problems and determine similarities in graphs. To detect wake lock leaks, we extract the call graph as features from the APK and embed the instruction and neighbor information in the node’s label of the call graph. Then, the encoded data are input to an MLP model for training and testing. We demonstrate that our model can identify wake lock leaks in apps with 99% accuracy.
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Awotiwon, Ajibola, Charlie Sword, Tracy Eastman, Christy Joy Ras, Prince Ana, Ruth Vania Cornick, Lara Fairall, et al. "Using a mentorship model to localise the Practical Approach to Care Kit (PACK): from South Africa to Nigeria." BMJ Global Health 3, Suppl 5 (October 2018): e001079. http://dx.doi.org/10.1136/bmjgh-2018-001079.

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Nigeria, in its quest to strengthen its primary healthcare system, is faced with a number of challenges including a shortage of clinicians and skills. Methods are being sought to better equip primary healthcare clinicians for the clinical demands that they face. Using a mentorship model between developers in South Africa and Nigerian clinicians, the Practical Approach to Care Kit (PACK) for adult patients, a health systems strengthening programme, has been localised and piloted in 51 primary healthcare facilities in three Nigerian states. Lessons learnt from this experience include the value of this remote model of localisation for rapid localisation, the importance of early, continuous stakeholder engagement, the need expressed by Nigeria’s primary healthcare clinicians for clinical guidance that is user friendly and up-to-date, a preference for the tablet version of the PACK Adult guide over hard copies and the added value of WhatsApp groups to complement the programme of face-to-face continuous learning. Introduction of the PACK programme in Nigeria prompted uptake of evidence-informed recommendations within primary healthcare services.
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Bury, Sophie, and Ron Sheese. "Academic Literacies as Cornerstones in Course Design: A Partnership to Develop Programming for Faculty and Teaching Assistants." Journal of University Teaching and Learning Practice 13, no. 3 (July 1, 2016): 26–44. http://dx.doi.org/10.53761/1.13.3.3.

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We discuss an educational development approach to embedding academic literacies instruction within disciplinary curricula. This developmental, embedded approach contrasts with the generic, extracurricular, study-skills approach adopted in many universities. Learning Commons partners at York University, including librarians, writing instructors, and learning skills counsellors, collaborated with educational developers in the York Teaching Commons to design a program for course instructors and teaching assistants (TAs) who seek to improve their students’ academic literacies. This program includes interactive workshops focusing on strategies to facilitate the redesign of courses and assignments so as to give explicit attention to process-related practices and abilities involved in library research and writing. The academic theory underpinning this program is outlined along with its key content elements. We also describe how the program draws on SPARK (Student Papers and Academic Research Kit), an online resource, created by the York Learning Commons under a Creative Commons license with the goal of helping students succeed with written academic assignments. Feedback from instructors and TAs support that the program has played an important role in helping them to question their assumptions and redesign their teaching practice.
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Kado, H., M. Higuchi, M. Shimogawara, Y. Haruta, Y. Adachi, J. Kawai, H. Ogata, and G. Uehara. "Magnetoencephalogram systems developed at KIT." IEEE Transactions on Appiled Superconductivity 9, no. 2 (June 1999): 4057–62. http://dx.doi.org/10.1109/77.783918.

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Harpham, Quillon, Paul Cleverley, and David Kelly. "The FluidEarth 2 implementation of OpenMI 2.0." Journal of Hydroinformatics 16, no. 4 (December 16, 2013): 890–906. http://dx.doi.org/10.2166/hydro.2013.190.

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Following the release of the OpenMI 2.0 standard for model coupling with reference object classes (interfaces) in C# and Java, a set of tools including a Software Development Kit (SDK) and Graphical User Interface (GUI) is expected to accompany it. These are necessary to enable numerical model developers to easily adapt their models to become OpenMI compliant and to allow modellers to easily assemble and run compositions of them. FluidEarth 2 is an HR Wallingford initiative providing these open source tools for the .net 4.0 Framework together with training, community support and sample models. They are the only such open source tools available so in this sense they act as the reference SDK and GUI for OpenMI 2.0 with .net. The purpose of this paper is to outline these and demonstrate a set of examples. A series of components were successfully constructed and compositions built. These include training models designed to demonstrate different aspects of model coupling, moving to industry strength model codes simulating dam-break bathymetry updates. The FluidEarth 2 tools have been designed to be cross-platform and have been tested under Windows and Linux (using Mono). Usage is successfully demonstrated, providing an environment for integrated modelling with OpenMI 2.0.
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Yegoshyna, G. A., S. M. Voronoy, and A. A. Ovdieichuk. "LEARNING SYSTEM DESIGN FOR GAME APPLICATIONS." Proceedings of the O.S. Popov ОNAT 1, no. 2 (December 31, 2020): 82–91. http://dx.doi.org/10.33243/2518-7139-2020-1-2-82-91.

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The presented paper investigates the problem of designing a learning system for agents in intelligent game applications based on Unity Game Engine and reinforcement machine learning algorithms. Modern trends in the game applications development are characterized by the active using of the concept of an intelligent agent as a behavior model of an active element in various situations with applying various strategies for interactions with other active elements and the environment. In recent years, there have been a significant number of advances in this area, such as DeepMind and the Deep Q learning architecture, the winning of the Go Game Champion with AlphaGo, OpenAI and PPO. Unity developers have implemented a support for machine learning and, in particular, for deep reinforcement learning in order to create a deep reinforcement learning the SDK (Software Development Kit) for game and simulation developers. With Unity and ML-Agents toolkits we can create physically, visually, and cognitively rich environments, including ones for evaluating new algorithms and strategies. However, learning system design for agents in Unity ML-Agents is possible only by using the Python API. The possibility of a learning system design for agents in the Flappy Bird game application based on the Unity Game Engine with using its own environment is discussed in this paper. Separately, the paper highlights typical features of the Flappy Bird gaming application environment. The environment can be implemented as a fully observable environment or a partially observable environment. The fully observable environment is suggested to be used due to all environment states in this case are seen in the playfield. Thus, the problem of strategy formation is considered as a Markov decision-making process and the agent directly observes the current state of the environment. Temporal Difference Learning is used as a learning method; it involves the assessment of a reward at each stage. Two separate environments, deterministic and stochastic, have been implemented, that allows to conduct further research and evaluation of strategy formation algorithms.
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Hadi, Usaamah, Entin Hidayah, and Gusfan Halik. "EVALUATION OF DRAINAGE SYSTEM PERFORMANCE AT MEDOKAN AYU DISTRICT SURABAYA CITY." Jurnal Rekayasa Sipil dan Lingkungan 3, no. 1 (June 3, 2019): 49. http://dx.doi.org/10.19184/jrsl.v3i1.9350.

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The problem of flood inundation in the Kebon Agung River at the Medokan Ayu Village, Rungkut District Surabaya, is getting worse due to the conditions of topographic, soil properties, high rainfalls, rising sea tides and very significant changes in land use. The eastern part of Surabaya, which was formerly open space land and now developed into a residential area. Therefore in the area, there is often flood inundation when the rainy season due to lack of recharge areas and poor drainage facilities. The performance evaluation of the drainage system was carried out using the SWMM program that is combining hydrology and hydraulic analysis. Hydrology analysis is used to determine various rainfall return periods. The maximum rainfall data are collected for 18 years. The hydraulic analysis is used to obtain the data in the form of cross-section, roughness, and drainage channel capacity. The results of the evaluation of drainage system modeling with SWMM have obtained the inundation points, namely for channels K3-K4-K5- K6-K7-K8 on the right side and Ki2-Ki3-Ki4-Ki5 on the left side. Pemasalahan genangan banjir di Kali Kebon Agung di Kelurahan Medokan Ayu Kecamatan Rungkut Surabaya menjadi semakin parah karena kondisi topografi, sifat tanah, tingginya intensitas hujan, meningkatnya pasang surut air laut dan perubahan tata guna lahan yang sangat signifikan. Wilayah Surabaya bagian timur yang semula lahan terbuka kini berkembang menjadi daerah perumahan. Oleh sebab itu di wilayah tersebut sering terjadi genangan banjir saat musim hujan dikarenakan kurangnya daerah resapan dan fasilitas drainase yang kurang baik. Evaluasi kinerja sistem drainase pada wilayah tersebut dilakukan dengan menggunakan pemodelan SWMM yang megabungkan pemodelan hidrologi dan hirdolika. Analisis hidrologi digunakan untuk menentukan berbagai kala ulang hujan. Data curah hujan maksimum digunakan selama 18 tahun. Analisis hidrolika digunakan untuk memperoleh data berupa penampang, kekasaran, dan kapasitas saluran drainase. Hasil running SWMM didapatkan titik titik lokasi genangan pada saluran K3-K4-K5-K6- K7-K8 pada sisi kanan dan Ki2-Ki3-Ki4-Ki5 pada sisi kiri.
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Abyshko, Alexander, Maria Mironova, Alfia Mutygullina, Ivan Ponomarev, German Sabirov, and Anastasiya Chuvaeva. "Restrictions on freedom of expression in the video games industry in Russia." Interactive Entertainment Law Review 2, no. 1 (June 2019): 23–34. http://dx.doi.org/10.4337/ielr.2019.01.02.

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The video games industry is expanding globally, and such markets as Russia have a potential for further growth attracting more and more publishers, and pushing compliance with Russian law into the business frontlines. The aim of this article is to give to the video games developers a survival kit on the Russian market highlighting the most problematic areas for foreign publishers, such as censorship, age ratings and restricted content. The most recent trends in judicial and administrative practice show that Russian jurisdiction is extended by official bodies to foreign businesses targeting the Russian market. The LinkedIn case discussed in this article is a representative example of such an approach. More recently, the district court of Kirov decided to block access on AppStore and Google Play to video games promoting criminal subculture. On the one hand, there are some positive trends for the game industry, like the activity of the Russian government in the field of regulating video games, namely, the Ministry of Sports of the Russian Federation has recently recognized eSports as an official sport. On the other hand, the Russian market conceals many pitfalls, for example, with regard to restricted content. The situation with respect to freedom of expression, ideas and information continues to deteriorate in all spheres of public life with video games being no exception.
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Su, Ming-Yang, Hong-Siou Wei, Xin-Yu Chen, Po-Wei Lin, and Ding-You Qiu. "Using Ad-Related Network Behavior to Distinguish Ad Libraries." Applied Sciences 8, no. 10 (October 9, 2018): 1852. http://dx.doi.org/10.3390/app8101852.

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Mobile app ads pose a far greater security threat to users than adverts on computer browsers. This is because app developers must embed a Software Development Kit (SDK), called an ad library or ad lib for short, provided by ad networks (i.e., ad companies) into their app program, and then merge and compile it into an Android PacKage (APK) execution file. The ad lib thus becomes a part of the entire app, and shares the whole permissions granted to the app. Unfortunately, this also resulted in many security issues, such as ad libs abusing the permissions to collect and leak private data, ad servers redirecting ad requests to download malicious JavaScript from unknown servers to execute it in the background of the mobile operating system without the user’s consent. The more well-known an embedded ad lib, the safer the app may be, and vice versa. Importantly, while decompiling an APK to inspect its source code may not identify the ad lib(s), executing the app on a simulator can reveal the network behavior of the embedded ad lib(s). Ad libs exhibit different behavior patterns when communicating with ad servers. This study uses a dynamic analysis method to inspect an executing app, and plots the ad lib behavior patterns related to the advertisement into a graph. It is then determined whether or not the ad lib is from a trusted ad network using comparisons of graph similarities.
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Park and Choi. "Design and Implementation Procedure for an Advanced Driver Assistance System Based on an Open Source AUTOSAR." Electronics 8, no. 9 (September 12, 2019): 1025. http://dx.doi.org/10.3390/electronics8091025.

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In this paper, we present the detailed design and implementation procedures for an advanced driver assistance system (ADAS) based on an open source automotive open system architecture (AUTOSAR). Due to the increasing software complexity of ADAS, portability, component interoperability, and maintenance are becoming essential development factors. AUTOSAR satisfies these demands by defining system architecture standards. Although commercial distributions of AUTOSAR are well established, accessibility is a huge concern as they come with very expensive licensing fees. Open source AUTOSAR addresses this issue and can also minimize the overall cost of development. However, the development procedure has not been well established and could be difficult for engineers. The contribution of this paper is divided into two main parts: First, we provide the complete details on developing a collision warning system using an open source AUTOSAR. This includes the simplified basic concepts of AUTOSAR, which we have organized for easier understanding. Also, we present an improvement of the existing AUTOSAR development methodology focusing on defining the underlying tools at each development stage with clarity. Second, as the performance of open source software has not been proven and requires benchmarking to ensure the stability of the system, we propose various evaluation methods measuring the real-time performance of tasks and the overall latency of the communication stack. These performance metrics are relevant to confirm whether the entire system has deterministic behavior and responsiveness. The evaluation results can help developers to improve the overall safety of the vehicular system. Experiments are conducted on an AUTOSAR evaluation kit integrated with our self-developed collision warning system. The procedures and evaluation methods are applicable not only on detecting obstacles but other variants of ADAS and are very useful in integrating open source AUTOSAR to various vehicular applications.
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Gone, Swapna, Nicolas Kosa, Joseph Krebs, James Hungerford, Mary Trucksess, and Christina DeWitt. "Validation Study of MaxSignal® Histamine Enzymatic Assay for the Detection of Histamine in Fish/Seafood." Journal of AOAC INTERNATIONAL 101, no. 3 (May 1, 2018): 783–92. http://dx.doi.org/10.5740/jaoacint.17-0289.

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Abstract Bioo Scientific Corp. has developed a rapid enzymatic quantitative assay for the determination of histamine in seafood. Fresh/frozen tuna, canned tuna, pouched tuna, and frozen mahi mahi samples were used for the validation study under the specific guidelines of the AOAC Research Institute Performance Tested MethodsSM program. Recoveries ranged from 82 to 107% at concentrations ranging from 6 to 72 ppm, with RSDr values between 0.8 and 6.5% (6–72 ppm). The linearity of the assay ranged from 0 to 108 ppm, with R2 values exceeding 0.99. The LOD was 0.9 ppm and the LOQ was 2.6 ppm for frozen tuna, which gave the lowest background level of contaminant. Cross-reactivity of the assay was tested against 14 other biogenic amines and was found to be minimal for all (<0.5%), except for agmatine (4.1%) and putrescine (0.9%). There was no observable interference from any tested biogenic amines. Product consistency was verified by validating lot-to-lot variations and variations within the same lot. Overall recoveries for all tested matrixes were within the acceptable range (80–120%). A 1-year claimed shelf life of the kit at 4°C was verified by accelerated stability study data collected on days 1, 15, and 32 at 25°C and by real-time stability testing at 1-month, 6-month, and 1-year at 4°C. No difference in histamine detection was observed in ruggedness testing, in which minor changes were introduced to the assay protocol. Good agreement was observed between AOAC Official MethodSM977.13 and the MaxSignal® Histamine Enzymatic Assay method. Independent laboratory testing demonstrated that the MaxSignal method works with the same precision in the hands of minimally trained technicians as with the expert method developers. This study validates the performance of Bioo Scientific’s rapid enzymatic method.
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Çelebi, Bekir, Selçuk Kılıç, Murat Yeşilyurt, and Bülent Acar. "Francisella tularensis’in Moleküler Tanısında Yeni Geliştirilen Kullanıma Hazır Ticari PCR Kitinin Etkinliğinin Değerlendirilmesi." Mikrobiyoloji Bulteni 48, no. 1 (January 29, 2014): 135–42. http://dx.doi.org/10.5578/mb.6715.

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salih, Thair A., and Mohammad Basman Gh. "A novel Face Recognition System based on Jetson Nano developer kit." IOP Conference Series: Materials Science and Engineering 928 (November 19, 2020): 032051. http://dx.doi.org/10.1088/1757-899x/928/3/032051.

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Van Trinh, Mai, and Nguyen Dang Thuan. "USING SELF-MADE COMPUTERIZED EXPERIMENT KIT TO DEVELOPE CREATIVITY COMPETENCE OF PUPILS IN PHYSICS TEACHING IN VIETNAM HIGH SCHOOLS." Journal of Science, Educational Science 61, no. 11 (2016): 38–45. http://dx.doi.org/10.18173/2354-1075.2016-0214.

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Mascorro, Arturo, Francisco Mesa, Jose Alvarez, and Laura Cruz. "Native Development Kit and Software Development Kit Comparison for Android Applications." International Journal of Information and Communication Technologies in Education 6, no. 3 (November 27, 2017): 5–13. http://dx.doi.org/10.1515/ijicte-2017-0011.

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ABSTRACTA computational cost comparative study through both Java and C applications was developed. Computational routines consist of a matrix multiplications, the discrete cosine transform and the bubble-sorting algorithm. Memory and Runtime for each application were measure. It was determined that the runtime of matrix multiplication in Java was within the limits of 200 and 300 milliseconds, as opposed to the application developed in C, which shown to be stable with an execution period less than 20 milliseconds. In the ordering algorithm with the bubble method, it was observe that the Java language show be very slow compared to C. In addition, the memory usage was lower in most of the applications, showing a minimum difference. Applications were tested in both, a mobile LG-E510f and a Laptop Toshiba Satellite. The study allowed to report the profit generated in both runtime and memory consumption when performing a native implementation in C and Java.
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Gutierrez, Ma Teodora E., Arriane A. Palisoc, Kristel Lirio, Winly Secreto, Ronald Taruc, and Klienne Noble. "Ergonomically Designed and Developed “Go-Bag” For School Children: A Survival Kit." Procedia Engineering 212 (2018): 651–58. http://dx.doi.org/10.1016/j.proeng.2018.01.084.

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Speers, Vanessa. "Development of the CCRU kit squad: Centralization of biospecimen “kit” management." Journal of Clinical Oncology 36, no. 30_suppl (October 20, 2018): 295. http://dx.doi.org/10.1200/jco.2018.36.30_suppl.295.

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295 Background: Personalized medicine has resulted in a rapid increase in biospecimens collection. Each biospecimen collected requires supplies that are provided in the form of “kits”. The number of kit types per protocol ranges anywhere from 2-60, with an average of 30 different kit types per trial. Historically, each trials nurse has managed their own kits resulting in large amounts of nursing time being spent on kit management. Kits took up a large amount of space in clinical areas, including expired kits, and they were being managed in no standardized fashion. Due to rapidly increasing biospecimen volumes, existing methods of kit management were no longer feasible and the CCRU Kit Squad was developed. Methods: Over the course of 12-mos, an extensive assessment of current kit management practices were reviewed with all disease site groups, including workflows and quantities utilized. An e-commerce software platform was selected, and semi-customized to centralize online ordering and receiving of kits, and the creation of a central location was setup for kit storage and daily operations. On-boarding of each group included retrieving existing kits from each nurse, uploading kits to the software, training each nurse to use the software, setting up accounts with each respective vendor for deliveries and re-supply, and disposing of expired kits. Results: Disease site groups were transitioned to the CCRU Kit Squad stepwise from Oct 2016 to Dec 2017 (15-mos), which included 80 nurses, 16 disease site groups, and over 400 clinical trials. By the end of 2017, the average number of kits ordered per day, and per month were 33 and 1003, respectively. Conclusions: The CCRU Kit Squad developed a centralized online service for kit management, thereby reducing administrative burden on clinical trial nurses. It has streamlined the management of biospecimen kits, eliminated wasted space in clinical areas, and facilitated the selection of the right kit for the right test at the right time.
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Pallaroni, Lea, Erland Björklund, Christoph von Holst, and Wolfgang Unglaub. "Determination of Rendering Plant Sterilization Conditions Using a Commercially Available ELISA Test Kit Developed for Detection of Cooked Beef." Journal of AOAC INTERNATIONAL 84, no. 6 (November 1, 2001): 1884–90. http://dx.doi.org/10.1093/jaoac/84.6.1884.

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Abstract A commercially available enzyme-linked immunosorbent assay (ELISA) test kit developed for detection of cooked beef in meat samples was used to determine appropriate heat treatment of rendered materials. An improved extraction procedure increased the absolute difference in R-values between 2 rendered materials treated under different conditions (average temperature 129 and 134°C, respectively). To evaluate the influence of the main sterilization parameters on ELISA results, a factorial design approach was used. The parameters investigated were temperature, time, particle size, and meat composition. Lean meat samples containing beef and pork were sterilized under strictly controlled conditions in a laboratory autoclave. The experiments demonstrated that the R-values obtained with the ELISA test kit for beef are strongly influenced by temperature and time, whereas particle size has a minor influence. The proportion of bovine material did not have any impact on R-values. Autoclave-processed lean meat samples were analyzed by using an ELISA test kit for pork, which was validated in a collaborative trial. The ELISA test kit for pork proved to be more sensitive for the investigated parameters, thus verifying and extending previous investigations.
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Dong, Fang, Haitao Bai, Xiaofang Wang, Shanshan Zhang, Zhao Wang, Miner Xie, Sen Zhang, et al. "Mouse acute leukemia develops independent of self-renewal and differentiation potentials in hematopoietic stem and progenitor cells." Blood Advances 3, no. 3 (February 7, 2019): 419–31. http://dx.doi.org/10.1182/bloodadvances.2018022400.

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Abstract The cell of origin, defined as the normal cell in which the transformation event first occurs, is poorly identified in leukemia, despite its importance in understanding of leukemogenesis and improving leukemia therapy. Although hematopoietic stem cells (HSCs) and hematopoietic progenitor cells (HPCs) were used for leukemia models, whether their self-renewal and differentiation potentials influence the initiation and development of leukemia is largely unknown. In this study, the self-renewal and differentiation potentials in 2 distinct types of HSCs (HSC1 [CD150+CD41−CD34−Lineage−Sca-1+c-Kit+ cells] and HSC2 [CD150−CD41−CD34−Lineage−Sca-1+c-Kit+ cells]) and 3 distinct types of HPCs (HPC1 [CD150+CD41+CD34−Lineage−Sca-1+c-Kit+ cells], HPC2 [CD150+CD41+CD34+Lineage−Sca-1+c-Kit+ cells], and HPC3 [CD150−CD41−CD34+Lineage−Sca-1+c-Kit+ cells]) were isolated from adult mouse bone marrow, and examined by competitive repopulation assay. Then, cells from each population were retrovirally transduced to initiate MLL-AF9 acute myelogenous leukemia (AML) and the intracellular domain of NOTCH-1 T-cell acute lymphoblastic leukemia (T-ALL). AML and T-ALL similarly developed from all HSC and HPC populations, suggesting multiple cellular origins of leukemia. New leukemic stem cells (LSCs) were also identified in these AML and T-ALL models. Notably, switching between immunophenotypical immature and mature LSCs was observed, suggesting that heterogeneous LSCs play a role in the expansion and maintenance of leukemia. Based on this mouse model study, we propose that acute leukemia arises from multiple cells of origin independent of the self-renewal and differentiation potentials in hematopoietic stem and progenitor cells and is amplified by LSC switchover.
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Singh, Neetu. "Effectiveness of developed low cost adulteration kit towards consumer awareness and food adulteration." Annals of Horticulture 11, no. 2 (2018): 131. http://dx.doi.org/10.5958/0976-4623.2018.00027.0.

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Kraatz-Wadsack, Gabriele, Wolf Ahrens, and Johannes von Stuckrad. "ELISA screening of staphylococcal enterotoxins by means of a specially developed test kit." International Journal of Food Microbiology 13, no. 4 (August 1991): 265–72. http://dx.doi.org/10.1016/0168-1605(91)90084-3.

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30

Lindemann, Paula. "Brisbane Urban Aboriginal Materials Kit." Aboriginal Child at School 17, no. 2 (May 1989): 3–4. http://dx.doi.org/10.1017/s0310582200006660.

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The Brisbane Urban Aboriginal Materials were developed in response to a need - that is the scarcity of teaching materials related to urban Aboriginal lifestyles. They provide classroom materials for teachers which give insights into the lifestyles of Aboriginal people in Brisbane at this time.The materials provide both teachers and students with an opportunity to gain a greater understanding of the culture of urban Aborigines in Brisbane. In doing so, it is hoped the materials will enable teachers to present an accurate and positive view of urban Aboriginal lifestyles.
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Kitayama, H., T. Tsujimura, I. Matsumura, K. Oritani, H. Ikeda, J. Ishikawa, M. Okabe, et al. "Neoplastic transformation of normal hematopoietic cells by constitutively activating mutations of c-kit receptor tyrosine kinase." Blood 88, no. 3 (August 1, 1996): 995–1004. http://dx.doi.org/10.1182/blood.v88.3.995.995.

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Abstract The c-kit proto-oncogene encodes a receptor tyrosine kinase that is crucial to hematopoiesis, melanogenesis, and gametogeneis. Although the enzymatic activity of the c-kit product (KIT) is regulated by its ligand, both the Val559-->Gly (G559) mutation in the juxtamembrane domain and the Asp814-->Val (V814) mutation in the phosphotransferase domain lead to constitutive activation of KIT. By retroviral infection of hematopoietic progenitor cells with KIT(G559) or KIT(V814), KIT(G559) induced development of granulocyte/macrophage and mast-cell colonies in vitro without the addition of exogenous growth factors. KIT(V814) induced factor-independent growth of various types of hematopoietic progenitor cells, resulting in the development of mixed erythroid/myeloid colonies in addition to granulocyte/macrophage and mast-cell colonies. Furthermore, transplantation of KIT(G559) and KIT(V814)-infected bone marrow cells led to development of acute leukemia in one of 10 and six of 10 transplanted mice, respectively. No mice developed hematologic malignancies after transplantation of wild- type KIT-infected cells. Furthermore, transgenic mice expressing KIT(V814) developed acute leukemia or malignant lymphoma. These results demonstrate a direct role of the mutant KITs, particularly KIT(V814), in tumorigenesis of hematopoietic cells and suggest that similar mutations may contribute to the development of human hematologic malignancies.
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Kitayama, H., T. Tsujimura, I. Matsumura, K. Oritani, H. Ikeda, J. Ishikawa, M. Okabe, et al. "Neoplastic transformation of normal hematopoietic cells by constitutively activating mutations of c-kit receptor tyrosine kinase." Blood 88, no. 3 (August 1, 1996): 995–1004. http://dx.doi.org/10.1182/blood.v88.3.995.bloodjournal883995.

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The c-kit proto-oncogene encodes a receptor tyrosine kinase that is crucial to hematopoiesis, melanogenesis, and gametogeneis. Although the enzymatic activity of the c-kit product (KIT) is regulated by its ligand, both the Val559-->Gly (G559) mutation in the juxtamembrane domain and the Asp814-->Val (V814) mutation in the phosphotransferase domain lead to constitutive activation of KIT. By retroviral infection of hematopoietic progenitor cells with KIT(G559) or KIT(V814), KIT(G559) induced development of granulocyte/macrophage and mast-cell colonies in vitro without the addition of exogenous growth factors. KIT(V814) induced factor-independent growth of various types of hematopoietic progenitor cells, resulting in the development of mixed erythroid/myeloid colonies in addition to granulocyte/macrophage and mast-cell colonies. Furthermore, transplantation of KIT(G559) and KIT(V814)-infected bone marrow cells led to development of acute leukemia in one of 10 and six of 10 transplanted mice, respectively. No mice developed hematologic malignancies after transplantation of wild- type KIT-infected cells. Furthermore, transgenic mice expressing KIT(V814) developed acute leukemia or malignant lymphoma. These results demonstrate a direct role of the mutant KITs, particularly KIT(V814), in tumorigenesis of hematopoietic cells and suggest that similar mutations may contribute to the development of human hematologic malignancies.
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Tanaka, Reiko, Junko Ito, Ayaka Sato, and Kazuko Nishimura. "Evaluation of a Newly Developed Identification Kit, RID Zyme CAS Test, for Candida albicans." Nippon Ishinkin Gakkai Zasshi 46, no. 2 (2005): 125–28. http://dx.doi.org/10.3314/jjmm.46.125.

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Katus, Hugo A., Willi Gerhardt, Christian Hamm, Poul J. Jørgensen, Jan Rafkilde, and Edgar Peheim. "Multicenter evaluation of a newly developed enzyme immuno assay kit for cardiac troponin T." Journal of the American College of Cardiology 17, no. 2 (February 1991): A331. http://dx.doi.org/10.1016/0735-1097(91)92288-w.

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35

Kishida, T., A. Hirao, T. Matsuura, T. Katamine, H. Yamada, T. Sagawa, and S. Fujimoto. "Diagnosis of premature rupture of membranes with an improved alpha-fetoprotein monoclonal antibody kit." Clinical Chemistry 41, no. 10 (October 1, 1995): 1500–1503. http://dx.doi.org/10.1093/clinchem/41.10.1500.

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Abstract We developed a new kit for detecting alpha-fetoprotein (AFP) in leaked amniotic fluid (Eur J Obstet Gynecol Reprod Biol 1995;58:67-72). Later, we developed an improved AFP kit utilizing the same AFP monoclonal antibody. We compared this improved AFP test with the nitrazine test for 137 patients. The nitrazine test correctly diagnosed 62.1% of the cases, but the improved AFP kit diagnosed 98.0% for < 37 weeks of gestation (P < 0.001). The nitrazine test showed a specificity of 58.3%, whereas the AFP kit showed a 100% rate for detecting > or = 37 weeks of gestation (P < 0.01). The reaction time with the AFP kit is 90 s. This study has confirmed a high clinical efficacy of the improved AFP test kit as a method of diagnosis of premature rupture of fetal membranes.
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36

Kim, Sung-Kun, Jin-Seok Park, Jong-Sub Lee, and Chun-Woo Lee. "Hyundai-Kia develops liquefied petroleum gas hybrid powertrain." MTZ worldwide 71, no. 2 (February 2010): 20–24. http://dx.doi.org/10.1007/bf03227004.

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Kim, Sung-Kun, Jin-Seok Park, Jong-Sub Lee, and Chun-Woo Lee. "Hyundai-Kia Develops Liquefied Petroleum Gas Hybrid Powertrain." ATZautotechnology 10, no. 1 (January 2010): 34–38. http://dx.doi.org/10.1007/bf03247154.

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38

KUROKI, Haruo, Kaoru OGUCHI, and Tsutomu YAMAZAKI. "Usefulness of a Newly Developed Immunochromatographic Assay Kit for the Detection of Respiratory Syncytial Virus." Kansenshogaku Zasshi 89, no. 5 (2015): 574–78. http://dx.doi.org/10.11150/kansenshogakuzasshi.89.574.

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39

TACHIKAWA, Natsuo, Yukihiro YOSHIMURA, Tsunehiro SHIMIZU, Kentaro TOCHITANI, Tetsushi GOTO, Takahumi TSUNODA, Takuya ADACHI, et al. "Evaluation of a Newly Developed Campylobacter Antigen Detection Kit for Patients with Enteritis." Kansenshogaku Zasshi 91, no. 2 (March 20, 2017): 145–50. http://dx.doi.org/10.11150/kansenshogakuzasshi.91.145.

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40

Chakravarthy, Murali. "An indigenous minitracheostomy/cricothyroidotomy set developed from unused items from intra-aortic balloon pump kit." Journal of Anaesthesiology Clinical Pharmacology 29, no. 3 (2013): 418. http://dx.doi.org/10.4103/0970-9185.117089.

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41

Ulva, Siti Maria. "Developing PBL kit by utilizing blog in order to improve scientific process and problem solving skills in physics learning." Jurnal Inovasi Pendidikan IPA 3, no. 1 (April 6, 2017): 89. http://dx.doi.org/10.21831/jipi.v3i1.13678.

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The study aimed at generating PBL-based learning kit product by utilizing blog, at meeting the criteria of learning kit feasibility, at testing the effectiveness of learning kit that the researcher had developed and at identifying the learning participants’ scientific process and problem solving skills. In conducting the study, the researcher implemented the 4-D Model. The learning kit development started involved preliminary study, product design, expert and practitioner test, limited experiment and field experiment. The instruments that had been deployed in conducting the study consisted of validation sheet, learning management observation sheet, student response sheet, teacher interview sheet and learning results test. This study generated a product that consisted of lesson plan, teacher’s book, student’s book, student’s working sheet, blog and learning results assessment. The validation results showed that the learning kit that had been developed were feasible for implementation. Then, the experiment results showed that the learning kit that the researcher had developed met the criteria of effectiveness. Based on the pretest and the posttest results that was administered during the field experiment, students’ physics learning has increased approximately 17.10 point from the pretest average score, namely 58.20, and from the posttest average score, namely 75.30.
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Roohi, Samina, Shakera Khatoon Rizvi, and Syed Ali Raza Naqvi. "177Lu-DOTATATE Peptide Receptor Radionuclide Therapy: Indigenously Developed Freeze Dried Cold Kit and Biological Response in In-Vitro and In-Vivo Models." Dose-Response 19, no. 1 (January 1, 2021): 155932582199014. http://dx.doi.org/10.1177/1559325821990147.

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Somatostatin receptors (SStR) based 177Lu-DOTATATE therapy is known as one of the highly effective neuroendocrine tumors (NETs) treatment strategy. Development of DOTATATE freeze-dried kit for imaging and therapy of SStR positive NETs is a prime goal in neuroendocrine cancer research. The present work describes the development of 177Lu-DOTATATE freeze dried cold kit for indigenous needs, through technology development fund (TDF) program offered by Higher Education Commission (HEC) Pakistan. The parameters for freeze dried kit production was optimized and tested the stored lyophilized cold kits for different time intervals after labeling with 177Lu radioisotope. The effect of ligand to radionuclide ratio, pH and reaction time at 90°C was recorded. Five times greater molar concentration of ligand, pH 5 and 30 min reaction time were the effective reaction conditions for maximum radiochemical yield. The radiolabeling yield at 1 day, 1-week and 4-week post storing period showed ∼100% radiochemical yield. The biodistribution study using rat model depicted the absence of non-targeted accumulation while glomerular filtration rate also explains the rapid renal washout. Cytotoxicity study showed quite favorable results for subjecting the radiopharmaceutical to clinical practice in Pakistan.
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43

Nienhuis*, James, Betsy Barnard, and Michell Sass. "Connecting Fast Plants to Biotechnology." HortScience 39, no. 4 (July 2004): 875B—875. http://dx.doi.org/10.21273/hortsci.39.4.875b.

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We have developed a series of instructional materials integrating a proven teaching tool, Wisconsin Fast Plants, with hands-on molecular techniques. Many biotechnology techniques, including genomics, have developed to a point where appropriate modifications can result in classroom accessible instructional materials that will engage students and teachers. Three “kits” have been developed or are in the process of development. Kit 1-PCR and Fast Plants. This kit is designed to provide an introduction to PCR and a link to Wisconsin Fast Plants. This kit uses a specific robust primer, which can amplify a specific sequence in Brassica rapa (Fast Plants). This kit serves as a hands-on tool to familiarize students with DNA extraction, PCR, gel electrophoresis, and analysis of PCR products. Kit 2-Genetic Diversity—`Veggie interesting'. This kit is based on the development of a specific primer, which is polymorphic between B. rapa (Fast Plants) and B. oleracea (common vegetables). In this kit, we explore the use of molecular markers and PCR to determine the species classification of various Brassica subspecies. This kit can be used to teach students about plant diversity and the use of molecular biology techniques (such as PCR) to determine how plants are related to each other. Kit 3-Genomics. The primary biological component is a simplified DNA chip (microarray) specifically designed for visualization of differential gene expression. This chip contains Arabidopsis thaliana genes that have already been characterized in our laboratory that display differential expression in seedlings grown in light vs. dark. To simplify analysis, the chip contain approximately ten genes rather than the thousands that are typically spotted on research chip.
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44

Yoon, Hoijin. "Effort Analysis of Unit Testing Conducted by Non-Developer of Source Code." Journal of the Korea society of IT services 11, no. 4 (December 31, 2012): 251–62. http://dx.doi.org/10.9716/kits.2012.11.4.251.

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45

Botha, C. J., P. N. Laver, A. Singo, E. A. Venter, G. C. H. Ferreira, M. Rösemann, and J. G. Myburgh. "Evaluation of a Norwegian-developed ELISA to determine microcystin concentrations in fresh water." Water Supply 19, no. 3 (June 27, 2018): 743–52. http://dx.doi.org/10.2166/ws.2018.118.

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Abstract Cyanobacteria are known for their extensive and highly visible blooms in rivers or dams in Africa. One of the most important cyanobacteria is Microcystis aeruginosa which can synthesise various microcystins that may affect the health of humans and animals. Accurate and efficient detection of microcystins in water is thus important for public and veterinary health. Two enzyme-linked immunosorbent assays (ELISA), a commercially-available ELISA kit (Abraxis) and a newly-developed Norwegian ELISA (putatively cheaper and more robust) were used to detect microcystins in fresh water in South Africa. Water samples were collected monthly at two sites, the Hartbeespoort Dam and a crocodile breeding dam. Extremely high microcystin concentrations (exceeding 360 μg L−1) were detected in the Hartbeespoort Dam during January 2015, whereas the microcystin concentrations in the crocodile breeding dam peaked during March–April 2015. Both ELISAs were positively correlated when analysing water samples ‘as is’ and following resin adsorption and methanol extraction. However, following resin adsorption and methanol extraction of the water samples, the correlation between the two assays was much stronger. These results suggests that the two ELISAs provide comparable results. If the Norwegian-developed ELISA can be packaged and made available as a user-friendly kit, it could be used successfully in surveillance programmes to monitor microcystin concentrations in fresh water bodies in Africa.
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Mondrida, Gina, Triningsih Triningsih, Kristina Dwi Purwanti, Sutari Sutari, Sri Setyowati, V. Yulianti S, Wening Lestari, Agus Ariyanto, and Puji Widayati. "Comparison Study Between Local TSH IRMA Kit (CRRT) and Imported TSH IRMA Kit (Riakey, Korea)." JKPK (Jurnal Kimia dan Pendidikan Kimia) 4, no. 2 (August 31, 2019): 77. http://dx.doi.org/10.20961/jkpk.v4i2.29756.

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<p><em>Thyroid Stimulating Hormone</em> (TSH) is one of hormones that our body need for growth of brains, bones and other tissues and regulate the metabolism in the body. Normal range of TSH for adult is from 0.3 to 5.5 µIU/ml, whereas for baby ranged from 3 to 18 µIU/ml. An Immunoradiometricassay (IRMA) is one of immunoassay technique using radionuclide as the tracer to detect low quantity of analyte. This technique is suitable for determine TSH levels in human blood serum which has complex matrix and various concentration. The Center for Radioisotope and Radiopharmaceutical Technology (CRRT)-BATAN has developed a reagent of TSH IRMA kit. The aim of this research is to compare between local TSH IRMA kit (CRRT-BATAN) and imported TSH IRMA kit (Riakey, Korea) toward 110 adult samples obtained from PTKMR - BATAN. The results showed 97 samples as true negative, 5 samples as true positive, 1 sample as false negative and 7 samples false positive. The comparison study gave diagnostic sensitivity as much as 83.33 %, diagnostic spesificity as much as 93.27 % and accuracy as much as 92.72 %.</p>
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47

Brown, M. C., and R. J. Casasola. "Complete response in a melanoma patient treated with imatinib." Journal of Laryngology & Otology 126, no. 6 (April 19, 2012): 638–40. http://dx.doi.org/10.1017/s0022215112000527.

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AbstractBackground:Imatinib therapy has been successful in gastrointestinal stromal tumours containing mutation of the KIT gene. However, there are few reported cases of successful imatinib therapy in patients with melanoma containing KIT gene mutation or c-kit protein expression.Methods and results:A 52-year-old man developed metastatic melanoma from a primary melanoma in the left side of the nasopharynx. The tumour was positive for c-kit protein, and there was a KIT mutation in exon 11. He was treated with imatinib. A follow-up scan one year later showed a complete response. Treatment targeting the biological characteristics of melanoma proved successful in this patient.
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48

Athiyyah, Royhanun, Taufiq Al Farizi, and Dwi Nanto. "Improvement of Science Process Skills Through Sound Variable Intensity Level Tool Kit." Jurnal Penelitian & Pengembangan Pendidikan Fisika 6, no. 1 (June 30, 2020): 89–96. http://dx.doi.org/10.21009/1.06110.

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Science process skills (SPS) are essential to assist the learning of senior high school students according to the 2013 curriculum, which prioritizes a scientific approach. The learning method that supports SPS is experiment methods. Nevertheless, learning with experimental methods is still rarely applied in schools, especially in the sound intensity level concept. The reason is the limited number and variant of experiment tool kits to support learning in schools. This study aims to develop a sound variable intensity level sound tool kit based on development procedures proposed by Jan van de Akker (2006). Sound variable intensity level kit was developed based on tool kit, which was developed before by Fikri Habibi. Sound variable intensity level experiment kit was evaluated by several learning media and learning material experts before being tested on high school students in several stages, including the one-on-one evaluation stages, small group evaluations, and field tests. The researcher revised the sound variable intensity level kit based on suggestions from the experts and the students. After being revised, the sound variable intensity level kit was tested on summative evaluation. Based on the results of summative evaluations, the sound variable intensity level kit becomes a successful, practical, and effective learning support tool kit for improving the science process skills of the student in the concept of sound intensity level.
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49

McKernan, Stuart. "“Microscopic Explorations“: One Kit Many uses." Microscopy and Microanalysis 6, S2 (August 2000): 1174–75. http://dx.doi.org/10.1017/s1431927600038368.

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Since 1996 the Minnesota Microscopy Society (MMS) has had several different opportunities to use the “Microscopic Explorations” [1] handbook that has been developed by MSA in collaboration with the Lawrence Hall of Science [2] as part of their Great Explorations in Math and Science (GEMS) series. Initially we used a beta-test version of the manual and worked with several different schools in the St. Paul's school district. Since then we have broadened the range of our outreach, and have interacted with different school districts, as well as local museums and other youth and community organizations - including church youth groups, scout groups and local governments. One of the strengths of the manual is that it can be used in many ways, and is adaptable to the particular learning situation available. These opportunities can span the range from essentially uncontrolled interactibns with the general public, with its large age range and ability spectrum, to the very carefully structured setting of an ongoing, single-age class program.
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50

Lee, Sang-Yeon, Doo-Yi Oh, Jin Hee Han, Min Young Kim, Bonggi Kim, Bong Jik Kim, Jae-Jin Song, et al. "Flexible Real-Time Polymerase Chain Reaction-Based Platforms for Detecting Deafness Mutations in Koreans: A Proposed Guideline for the Etiologic Diagnosis of Auditory Neuropathy Spectrum Disorder." Diagnostics 10, no. 9 (September 4, 2020): 672. http://dx.doi.org/10.3390/diagnostics10090672.

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Routine application of next-generation sequencing in clinical settings is often limited by time- and cost-prohibitive complex filtering steps. Despite the previously introduced genotyping kit that allows screening of the 11 major recurring variants of sensorineural hearing loss (SNHL) genes in the Korean population, the demand for phenotype- and variant-specific screening kits still remains. Herein, we developed a new real-time PCR-based kit (U-TOP™ HL Genotyping Kit Ver2), comprising six variants from two auditory neuropathy spectrum disorder (ANSD) genes (OTOF and ATP1A3) and five variants from three SNHL genes (MPZL2, COCH, and TMC1), with a distinct auditory phenotype, making this the first genotyping kit dedicated to ANSD. The concordance rate with Sanger sequencing, sensitivity, and specificity of this genotyping kit were all 100%, suggesting reliability. The kit not only allows timely and cost-effective identification of recurring OTOF variants, but it also allows timely detection of cochlear nerve deficiency for those without OTOF variants. Herein, we provide a clinical guideline for an efficient, rapid, and cost-effective etiologic diagnosis of prelingual ANSD. Our study provides a good example of continuing to update new key genetic variants, which will continuously be revealed through NGS, as targets for the newly developed genotyping kit.
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