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Journal articles on the topic 'Development board Nucleo'

Author: Grafiati

Published: 4 June 2021

Last updated: 16 February 2022

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1

KORNAEV, A. V., I. N. STEBAKOV, S. G. POPOV, and Yu N. KAZAKOV. "CALCULATION OF THE MOBILE DEVICE OF THE BUILDING ROBOT FOR SUSTAINABILITY." Fundamental and Applied Problems of Engineering and Technology 3 (2020): 67–75. http://dx.doi.org/10.33979/2073-7408-2020-341-3-67-75.

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This article discusses the development of an affordable software and hardware complex for monitoring and diagnostics of rotary machines with fluid–film bearings. The software part of the complex was developed on the basis of a four–layer fully–connected artificial neural network. The network was trained and tested according to the results of experiments in a test rig. The contact resistance sensors measurement results were used as input for training. The basis of the hardware of the complex was the Nucleo–144 board with a trained network. Testing of the developed complex showed a diagnostic ac

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2

Ponto, James A. "Nuclear Pharmacy and the Board of Pharmaceutical Specialties (BPS)." Journal of Pharmacy Practice 2, no. 5 (1989): 299–301. http://dx.doi.org/10.1177/089719008900200507.

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Nuclear pharmacy was officially recognized as a specialty area in pharmacy practice, the first specialty area so recognized, by the Board of Pharmaceutical Specialties in 1978. Subsequently, a certification examination was developed and administered for the first time in 1982. By 1988, 112 nuclear pharmacists had become board certified in nuclear pharmacy. Although little tangible value was initially associated with certification, certification is gradually accruing worth with recent recognition and acceptance by the Nuclear Regulatory Commission and the National Association of Boards of Pharm

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3

Hammes, Richard J., David L. Laven, and Carmen Catizone. "Nuclear Pharmacy and the National Association of Boards of Pharmacy (NABP)." Journal of Pharmacy Practice 2, no. 5 (1989): 314–21. http://dx.doi.org/10.1177/089719008900200510.

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The challenges and opportunities involved in the emergence and regulation of pharmaceutical specialties are discussed in relationship to the historical and current developments regarding nuclear pharmacy. The issues of the state board of pharmacy v federal regulation of the practice of pharmacy, drug use control in institutions, and education and training of specialists are explored. The interaction of the National Association of Boards of Pharmacy (NABP) with professional nuclear pharmacy groups in addressing these issues is described. This is a US government work. There are no restrictions o

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Doan, Nhan Thi Thanh, Hai Hong Vo, and Hung Quoc Nguyen. "Development of environmental radiation monitoring system using inspector+ and FPGA board." Science and Technology Development Journal 18, no. 3 (2015): 29–35. http://dx.doi.org/10.32508/stdj.v18i3.816.

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In this report, we present the development of an environmental radiation monitoring system. The system includes Inspector+ dose meter, FPGA board, and LabVIEW interface. In the electronic board using FPGA, the embedded VHDL program is developed for FPGA board. Its functions are to accumulate pulse signals from the Inspector+, transmit data to the computer. Computer interface is written on LabVIEW platform. Its functions are to receive data from FPGA board, plot data, store data, as well as control the FPGA board. We evaluate the response of the system by using a standard pulse generator. With

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Braun, Theodore, Theresa Lusardi, Trevor Enright, et al. "Single Cell RNA Sequencing Identifies a Crucial Role for ASXL1 in Neutrophil Development." Blood 134, Supplement_1 (2019): 212. http://dx.doi.org/10.1182/blood-2019-125022.

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Single Cell RNA Sequencing Identifies a Crucial Role for ASXL1 in Neutrophil Development Additional sex combs-like 1 (ASXL1) is a polycomb-associated protein that is essential for normal hematopoiesis. ASXL1 is recurrently mutated across the spectrum of myeloid malignancies including myelodysplastic syndromes, myeloproliferative neoplasms and Acute Myeloid Leukemia. ASXL1 mutations are also found in the premalignant disorders clonal hematopoiesis of indeterminate potential and clonal cytopenias of indeterminate potential. In all cases, ASXL1 mutations are associated with more aggressive diseas

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Xuan, M. F., S. Z. Han, B. H. Quan, X. J. Yin, and J. D. Kang. "118 Semen quality and fertilization ability of myostatin-knockout boars." Reproduction, Fertility and Development 32, no. 2 (2020): 186. http://dx.doi.org/10.1071/rdv32n2ab118.

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Myostatin-knockout (MSTN−/−) pigs may provide a source of healthy lean protein for human consumption. However, little is known about the effect of this knockout on semen quality, which is important if these pigs are used for production. The purpose of this study is to evaluate the semen quality and fertility of MSTN−/− boars. We generated MSTN−/− boars from Duroc-Landrace-Yorkshire hybrid pig cell lines by somatic cell nuclear transfer, and all 12 boars showed sexual maturation with an obvious “double muscling” phenotype. Semen was collected randomly from three MSTN−/− boars using the gloved-h

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7

Susila, I. Putu, Agung Alfiansyah, Istofa Istofa, Sukandar Sukandar, Budi Santoso, and Suratman Suratman. "DEVELOPMENT OF MOBILE DEVICE FOR GAMMA RADIATION MEASUREMENT UTILIZING LORA AS THE COMMUNICATION MEANS." JURNAL TEKNOLOGI REAKTOR NUKLIR TRI DASA MEGA 21, no. 2 (2019): 79. http://dx.doi.org/10.17146/tdm.2019.21.2.5432.

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Public protection is one of important issues when operating nuclear facility. In case of accident occurs, the facility owner and related organizations shall make decision whether to evacuate people or not, based on the level of the accident and radiation dose rate released to the environment. In this study, as part of the decision support system for nuclear emergency response, a prototype of mobile radiation measurement system has been developed. The device consists of Geiger-Muller (GM)-based radiation measurement board, Global Positioning System (GPS) module, microcontroller board, and low p

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8

Makino, J. "Current Status of GRAPE Project." Proceedings of the International Astronomical Union 3, S246 (2007): 457–66. http://dx.doi.org/10.1017/s1743921308016165.

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AbstractI'll summarize the current status of GRAPE project. GRAPE-6, completed in 2002, has been used by a number of people, for a wide variety of problems such as planet formation, star cluster dynamics, galactic nuclei, and cosmology. In 2004, we started the development of the next-generation machine, GRAPE-DR. GRAPE-DR has a architecture radically different from that of previous GRAPEs. It does not have hardwired pipeline for gravitational force calculation but a large number of small and simple programmable processors. This change made it possible to apply GRAPE-DR to a wide range of probl

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9

Aritonang, Sovian, Nining Parlina, and Yanif Dwi Kuntjoro. "Government Strategy To Improve Public Acceptance Toward Nuclear Power Plant." Jurnal Pertahanan 4, no. 1 (2018): 24. http://dx.doi.org/10.33172/jp.v4i1.250.

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<p>This research to discuss the Government's strategy to increase public acceptance toward nuclear power development plan. The purpose of this research is to obtain recommendation for government’s strategy. It is design as descriptive qualitative one with design research. The results showed there are two strategies, namely; strategies of socialization through counseling and through online media. Based on the research, it is recommended that the government should establish a Coordination Board which is under the command of (under command) specifically in the case of nuclear power plants i

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10

Shi, Junsong, Baohua Tan, Lvhua Luo, et al. "Assessment of the Growth and Reproductive Performance of Cloned Pietrain Boars." Animals 10, no. 11 (2020): 2053. http://dx.doi.org/10.3390/ani10112053.

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How to maximize the use of the genetic merits of the high-ranking boars (also called superior ones) is a considerable question in the pig breeding industry, considering the money and time spent on selection. Somatic cell nuclear transfer (SCNT) is one of the potential ways to answer the question, which can be applied to produce clones with genetic resources of superior boar for the production of commercial pigs. For practical application, it is essential to investigate whether the clones and their progeny keep behaving better than the “normal boars”, considering that in vitro culture and trans

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11

LEGGER, F., A. BAY, G. HAEFELI, and L. LOCATELLI. "TELL1: development of a common readout board for LHCb." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 535, no. 1-2 (2004): 497–99. http://dx.doi.org/10.1016/s0168-9002(04)01715-2.

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12

Shamsuddin, Shazmeen Daniar, Nurlyana Omar, and Meng Hock Koh. "Development of radionuclide dispersion modeling software based on Gaussian Plume model." MATEMATIKA 33, no. 2 (2017): 149. http://dx.doi.org/10.11113/matematika.v33.n2.1003.

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It has come to attention that Malaysia have been aiming to build its own nuclear power plant (NPP) for electricity generation in 2030 to diversify the national energy supply and resources. As part of the regulation to build a NPP, environmental risk assessment analysis which includes the atmospheric dispersion assessment has to be performed as required by the Malaysian Atomic Energy Licensing Board (AELB) prior to the commissioning process. The assessment is to investigate the dispersion of radioactive effluent from the NPP in the event of nuclear accident. This article will focus on current d

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13

Nakai, Michiko, Naomi Kashiwazaki, Akiko Takizawa, et al. "Morphologic changes in boar sperm nuclei with reduced disulfide bonds in electrostimulated porcine oocytes." Reproduction 131, no. 3 (2006): 603–11. http://dx.doi.org/10.1530/rep.1.01001.

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In pigs, failure of sperm nuclear decondensation has been reported after injection into oocytes. We examined the effects of pretreating sperm heads with Triton X-100 (TX-100) and dithiothreitol (DTT) and of electrical stimulation of oocytes after sperm head injection on time-dependent morphologic changes in sperm nuclei andin vitrodevelopment to the blastocyst stage. In experiment 1, spermatozoa were pretreated with 1% TX-100 and 5 mM DTT (T + D) or not treated, and then injected intoin vitromatured oocytes. Electrical stimulation (1.5 kV/cm, 20 μs DC pulse) was applied to the oocytes 1 h afte

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Sibczynski, Pawel, Andrzej Dziedzic, Krystian Grodzicki, et al. "New perspectives for undoped CaF2 scintillator as a threshold activation neutron detector." EPJ Web of Conferences 170 (2018): 07012. http://dx.doi.org/10.1051/epjconf/201817007012.

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In this paper we present the prompt photofission neutron detection performance of undoped CaF2 scintillator using Threshold Activation Detection (TAD). The study is carried out in the frame of C-BORD Horizon 2020 project, during which an efficient toolbox for high volume freight non-intrusive inspection (NII) is under development. Technologies for radiation monitoring are the part of the project. Particularly, detection of various radiological threats on country borders plays an important significant role in Homeland Security applications. Detection of illegal transfer of Special Nuclear Mater

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15

Evenson, D. P., K. Kasperson, R. L. Wixon, and B. A. Didion. "228 BOAR FERTILITY AND SPERM CHROMATIN STRUCTURE ASSAY DEFINED SPERM DNA FRAGMENTATION." Reproduction, Fertility and Development 21, no. 1 (2009): 212. http://dx.doi.org/10.1071/rdv21n1ab228.

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The sperm chromatin structure assay (SCSA) was used retrospectively to characterize sperm from 18 sexually mature boars having fertility information. Boar fertility was defined by farrowing rate (FR) and average total number of pigs born (ANB) per litter of gilts and sows mated to individual boars. The SCSA uses flow cytometry to evaluate the structural integrity of sperm nuclear DNA. In brief, aliquots of frozen/thawed semen were treated for 30 s with a pH 1.2 buffer that denatures sperm DNA at the sites of DNA strand breaks. The samples are then stained with acridine orange (AO) that interca

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16

Masincup, W. E., J. S. Bryan, and L. M. Ochs. "Development of an Interactive Electronic Technical Manual." Journal of Engineering for Gas Turbines and Power 118, no. 3 (1996): 632–35. http://dx.doi.org/10.1115/1.2816695.

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For a number of years, the Navy has been pursuing a means of reducing or eliminating the amount of paper carried on board ship. In particular, technical manuals consume large amounts of storage space. The paper provides a case study of the development of a gas turbine technical manual into an interactive electronic (computerized) format. This paper presents some of the difficulties of the development process, enhancements that have been developed, software selection, graphics complexity, and hardware definition. In addition, a detailed description of a final product will be provided.

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17

Lu, Houbing, Feng Li, Peng Miao, et al. "Development of FEB Configuration Test Board for ATLAS NSW Upgrade." IEEE Transactions on Nuclear Science 66, no. 8 (2019): 2028–32. http://dx.doi.org/10.1109/tns.2019.2929232.

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18

Gabrielli, Alessandro, Enzo Gandolfi, and Pier Paolo Ricci. "Development of an electronic board for a neutrino telescope project." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 556, no. 1 (2006): 302–7. http://dx.doi.org/10.1016/j.nima.2005.09.047.

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19

IDO, Shunji, Ryusuke TSUJI, and Yasuaki NAKAI. "Development of board using 25MHz transputer and its performances of FORTRAN calculations." Journal of the Atomic Energy Society of Japan / Atomic Energy Society of Japan 31, no. 2 (1989): 273–75. http://dx.doi.org/10.3327/jaesj.31.273.

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20

Sheiko, I. P. "New ways and methods of development of pig breeding in Belarus." Proceedings of the National Academy of Sciences of Belarus. Agrarian Series 58, no. 1 (2020): 68–78. http://dx.doi.org/10.29235/1817-7204-2020-58-1-68-78.

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The Republic of Belarus has a well-developed pig breeding industry. The main goal in pig breeding in Belarus is to obtain, in a short time, competitive breeds, types and hybrids of pigs adapted to the conditions of industrial pork production and not inferior to analogues of the world breeding. Currently, in the pig industry, effective variants of interbreeding hybridization are widely introduced, and mating of specialized maternal breeds (BLW × BM) and (Y × L) with boars of specialized paternal breeds (D, P). Piglets obtained during interbreeding hybridization have a heterosis effect in feedin

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21

Morgoshiia, T. Sh, and N. A. Syroezhin. "In memory of professor L.S. Rosenstrauch. To the 100th anniversary." Medical Visualization, no. 4 (December 26, 2019): 131–35. http://dx.doi.org/10.24835/1607-0763-2019-4-131-135.

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The article presents the main stages of life and work of the professor L.S. Rosenstrauch (1918–2016). L.S. Rosenstrauch is the author of more than 300 scientific papers including 10 monographies. The important direction of his scientific works was development of new radiological techniques such as parasternal mediastinography, and development and integration of the domestic contrast agents. L.S. Rosenstrauch intensively engaged in teaching. More than 30 doctoral and more than 60 candidate dissertations were defended under his guidance or consultation. Professor was a honorary member of domesti

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22

Ohata, Toru, Hiroyuki Konishi, Hiroaki Kimura, et al. "SPring-8 beamline control system." Journal of Synchrotron Radiation 5, no. 3 (1998): 590–92. http://dx.doi.org/10.1107/s0909049597016038.

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The SPring-8 beamline control system is now taking part in the control of the insertion device (ID), front end, beam transportation channel and all interlock systems of the beamline: it will supply a highly standardized environment of apparatus control for collaborative researchers. In particular, ID operation is very important in a third-generation synchrotron light source facility. It is also very important to consider the security system because the ID is part of the storage ring and is therefore governed by the synchrotron ring control system. The progress of computer networking systems an

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23

Parrish, J. J., C. Mueller, E. Ludwig, and J. L. Susko-Parrish. "226 DAY LENGTH DOES NOT AFFECT LIVE SPERM NUCLEAR SHAPE IN THE STALLION." Reproduction, Fertility and Development 20, no. 1 (2008): 192. http://dx.doi.org/10.1071/rdv20n1ab226.

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Fourier harmonic analysis (FHA) of sperm nuclei is a precise and objective method to evaluate shape of the sperm head, with the calculated harmonic amplitudes highly related to male fertility. The FHA approach has been developed for use in the bull and the boar but has not yet been applied to the stallion. Direct utilization of the previous fluorescent approaches to identify and image live sperm nuclei in the bull cannot be used in the stallion due to the increased thickness of the post-nuclear region and thin anterior region of the sperm head. An alternative approach was developed in which li

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Williams, N. E., S. C. Walker, D. E. Reeves, et al. "A Comparison of Reproductive Characteristics of Boars Generated by Somatic Cell Nuclear Transfer to Highly Related Conventionally Produced Boars." Cloning and Stem Cells 8, no. 3 (2006): 130–39. http://dx.doi.org/10.1089/clo.2006.8.130.

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25

Harmata, Wladyslaw, Marek Witczak, and Grzegorz Pietrzak. "Aerial detection of contamination with the use of unmanned vehicles – development prospects." Scientific Journal of the Military University of Land Forces 187, no. 1 (2018): 5–24. http://dx.doi.org/10.5604/01.3001.0011.7353.

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Currently, the territory of the Republic of Poland faces a growing threat of contamination with its sources in catastrophes and technical failures in industrial plants (including nuclear power plants) and uncontrolled release of high-toxic chemicals during transport and, which cannot be excluded, terrorism. The increased level of threat resulting from, among others, those factors caused that the National Contamination Detection and Alerting Systems (KSWiA) with the Contamination Detection System of the Polish Armed Forces as the system coordinator was established in the Republic of Poland in 2

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26

Tai, Yu-Tzu, Yosef Landesman, Chirag Acharya, et al. "CRM1 Blockade by Novel Inhibitors of Nuclear Export (SINEs) Inhibits Multiple Myeloma Cell Growth, Osteoclastogenesis, and Myeloma-Induced Osteolysis." Blood 120, no. 21 (2012): 326. http://dx.doi.org/10.1182/blood.v120.21.326.326.

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Abstract Abstract 326 The key nuclear export protein CRM1 (chromosome region maintenance 1, Exportin 1, XPO1) may directly contribute to the pathophysiology of human multiple myeloma (MM). Here, we characterized the role of CRM1 in MM biology and defined molecular mechanisms whereby novel oral, irreversible, selective inhibitors of nuclear export (SINE) targeting CRM1 mediate anti-MM activity. CRM1 gene expression is increased with disease progression, since it is significantly elevated in active MM and plasma cell leukemia (PCL) vs. normal/MGUS/SMM patients (p< 0.02). CRM1 downregulation b

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27

Shimazoe, Kenji, Yeom-Jung Yeol, Yasuhiro Minamikawa, et al. "Development of 40 channel waveform sampling CMOS ASIC board for Positron Emission Tomography." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 573, no. 1-2 (2007): 99–102. http://dx.doi.org/10.1016/j.nima.2006.11.034.

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28

Garhwal, Rahul, Alan G. Rosmarin, Stephanie Halene, and Peter Gaines. "Transcriptional Regulation of the Nuclear Envelope Lamin B Receptor: New Roles for GA Binding Protein (GABP) in Neutrophil Development." Blood 114, no. 22 (2009): 1464. http://dx.doi.org/10.1182/blood.v114.22.1464.1464.

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Abstract Abstract 1464 Poster Board I-487 The essential roles that neutrophils play in innate immune responses require that these phagocytes rapidly migrate to sites of infection, adhere to and escape capillary epithelium, and then engulf and destroy invading pathogens. The capacity of neutrophils to perform these complicated functions is largely dependent on the actions of multiple hematopoietic transcription factors that coordinate the expression of critical functional genes during neutrophil development. These transcription factors include CCAAT/enhancer binding proteins C/EBPα and C/EBPε,

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29

Van Handel, Ben, Sacha Prashad, Andy Huang, et al. "The First Trimester Human Placenta Is An Embryonic Hematopoietic Organ with An Unexpected Function in Primitive Erythroid Maturation." Blood 114, no. 22 (2009): 1508. http://dx.doi.org/10.1182/blood.v114.22.1508.1508.

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Abstract Abstract 1508 Poster Board I-531 Developmental hematopoiesis satisfies the immediate needs of the embryo and provides the hematopoietic stem cells necessary for lifelong blood homeostasis. Recently, the mid-gestation mouse placenta was identified as an important definitive hematopoietic organ; data from us and others indicates that the human placenta functions analogously, harboring and potentially generating hematopoietic stem and progenitor cells. The function of the human placenta in embryonic hematopoiesis has not been addressed. We assessed the hematopoietic potential of placenta

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30

Nishida, Yuki, Jo Ishizawa, Vivian Ruvolo, et al. "Dual Inhibition of MDM2 and XPO1 Synergizes to Induce Apoptosis in Acute Myeloid Leukemia Progenitor Cells with Wild-Type TP53 through Nuclear Accumulation of p53 and Suppression of c-Myc." Blood 134, Supplement_1 (2019): 2556. http://dx.doi.org/10.1182/blood-2019-126950.

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Background. MDM2 is frequently overexpressed in acute myeloid leukemias (AML) and suppresses p53-mediated apoptosis while p53 mutations are relatively rare in AML. MDM2 inhibitors as a monotherapy have shown limited efficacy in clinical trials in AML (~25% response rate) (Andreeff, Clin Cancer Res 2015). XPO1 transports around 300 proteins, including p53 and other tumor suppressors, from the nucleus to the cytoplasm. Overexpression of XPO1 is associated with unfavorable outcomes in AML (Kojima, Blood 2013). p53 activation or XPO1 inhibition have been reported to decrease c-Myc protein levels t

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31

Li, Yunsheng, Ya Liu, Shiping Su, Yong Pu, Xiaorong Zhang, and Fugui Fang. "Immunization against recombinant GnRH-I alters testicular structure in an experimental boar model." Zygote 23, no. 1 (2013): 125–35. http://dx.doi.org/10.1017/s0967199413000397.

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SummaryThe aim of this study was to evaluate and to compare testicular tissue in immunized and control boars. Eighteen male piglets, aged 12 weeks, were vaccinated twice intramuscularly with a maltose-binding protein–gonadotropin-releasing hormone I hexamer peptide (MBP-GnRH-I6). Blood samples were taken at 12, 18, 21 and 24 weeks of age. Serum concentrations of testosterone and GnRH-I antibodies were determined by radioimmunoassay. The pigs were sacrificed 6 weeks after the second immunization. Testicular weight and size were recorded and tissue samples were collected for histological examina

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32

Gonzalez, V., E. Sanchis, J. Soret, et al. "Development of the Optical Multiplexer Board Prototype for Data Acquisition in the TileCal System." IEEE Transactions on Nuclear Science 53, no. 4 (2006): 2131–38. http://dx.doi.org/10.1109/tns.2006.877861.

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33

Kandarpa, Malathi, Stephanie J. Kraftson, Sean P. Maxwell, et al. "CRM1 Is Highly Expressed in Myeloma Plasma Cells and Its Inhibition by KPT-SINE Induces Cytotoxicity by Increasing p53 in the Nucleus of Multiple Myeloma (MM) Cells." Blood 118, no. 21 (2011): 1852. http://dx.doi.org/10.1182/blood.v118.21.1852.1852.

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Abstract Abstract 1852 Background: CRM1 (XPO1, exportin) is a nuclear export protein which controls the nuclear-cytoplasmic localization of multiple tumor suppressor proteins and cell proliferation pathways including p53, p21, PI3K/AKT/FOXO, Wnt/ß-catenin/APC, topoisomerase II, and NF-κB/I-κB. Transport of nuclear proteins to the cytoplasm can render them ineffective as tumor suppressors or as targets for chemotherapy. Small molecule, selective inhibitors of nuclear export (SINE) that block CRM1-dependent nuclear export can force the nuclear retention of tumor suppressor proteins, thus renderi

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Caponetto, L., A. Gabrielli, E. Gandolfi, F. M. Giorgi, D. Lo Presti, and N. Randazzo. "Development realization and test of an electronic data acquisition board for the NEMO experiment." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 596, no. 1 (2008): 103–6. http://dx.doi.org/10.1016/j.nima.2008.07.120.

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35

da Palma Guerreiro, Alexandra, Cornelia Dorweiler, Laurent Kintzelé, et al. "Loss of TOSO Promotes Richter's Transformation of TCL1A Driven CLL." Blood 128, no. 22 (2016): 354. http://dx.doi.org/10.1182/blood.v128.22.354.354.

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Abstract Background: The immunoglobulin-like protein TOSO, which has been found to serve as Fc receptor for IgM (FcµR), was shown by us and others to be overexpressed on CLL cells and only weakly expressed on more aggressive B-NHL. However the functional role of TOSO on lymphomagenesis has not been explored so far. Methods: To determine the role of TOSO on lymphoma development, we took advantage of the Eµ-TCL1 transgenic mice, which usually end up with an aggressive (IgVH unmutated) CLL-like phenotype. We generated a novel B cell-specific conditional knockout (KO) mouse model in which EµTCL1 m

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Sakhuja, Kiran B., Lina A. Gugliotti, Yutaka Suzuki, et al. "Constitutive Lymphoid Expression of the Nuclear Form of RNase H1 Is Associated with Development of Immature B Cell Lymphomas." Blood 114, no. 22 (2009): 1613. http://dx.doi.org/10.1182/blood.v114.22.1613.1613.

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Abstract Abstract 1613 Poster Board I-639 Ribonuclease H1, which cleaves the RNA of RNA/DNA hybrids, plays a vital role in the replication of mitochondrial DNA during mouse embryogenesis, but its contributions to later mammalian development and adult biology are not known. In higher eukaryotes two isoforms of RNase H1, a nuclear form and mitochondrial form, are produced from a single transcript. To investigate the effects of constitutive high level RNase H1 expression, we generated transgenic (TG) mice, strain M27F7, with lymphocyte-specific over-expression of nuclear RNase H1. Transcripts in

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37

Moses, K. "The availability of coal." Proceedings of the Royal Society of Edinburgh. Section B. Biological Sciences 92, no. 1-2 (1987): 21–28. http://dx.doi.org/10.1017/s0269727000009490.

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SynopsisSince the assessment of coal reserves for the Royal Commission on the coal industry of Great Britain made nearly a century ago, up to assessments made by geologists of the National Coal Board, it has been evident that the coalfields of Scotland contain considerable quantities of coal. Throughout the past two decades the presence of hydrocarbons in the rocks beneath the North Sea, the general abundance of oil in various parts of the world, and the development of nuclear power, has meant that coal is only one of several sources of energy readily available to us. The coalfields of Scotlan

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38

Nishida, Yuki, Jo Ishizawa, Edward Ayoub, et al. "Exportin-1 (XPO1) Inhibition Sequesters p53 from MDM2 and MDM4 and Is Highly Synergistic with MDM2 Inhibition in Inducing Apoptosis in Wild-Type p53 Acute Myeloid Leukemias." Blood 136, Supplement 1 (2020): 23–24. http://dx.doi.org/10.1182/blood-2020-140768.

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The tumor suppressor p53 is inactivated in virtually all cancers, including leukemias, by mutations or deletion of the TP53 gene, or overexpression of negative regulators (e.g., MDM2, MDM4, and XPO1). MDM2 and MDM4 are frequently overexpressed in acute myeloid leukemia (AML), with the highest MDM4 expression as compared to other malignancies. XPO1 transports ~300 proteins, including p53, from the nucleus to the cytoplasm and MDM2 is also a cargo protein transported by XPO1.We previously reported high synergism by MDM2 and XPO1 inhibition in AML (Kojima et al., Blood 2013), with the underlying

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Yang, Woong, Soo-Hong Lee, Yong Zhu Jin, and Hyun-Tae Hwang. "Development of web-based collaborative framework for the simulation of embedded systems." Journal of Computational Design and Engineering 3, no. 4 (2016): 363–69. http://dx.doi.org/10.1016/j.jcde.2016.06.004.

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Abstract Cyber Physical System (CPS) and Internet of Things (IoT) are hot objects of interest as an extension of the embedded system. These interactive products and systems contain Mobile Devices which are most popular and used most frequently. Also these have been widely used from the control of the Nuclear Power Control System (NPCS) to IoT Home Service. Information & Communication Technology (ICT) topics of trend fused-complex current Information Technology (IT) and Communication Technology (CT) are closely linked to real space and virtual space. This immediately means the arrival of th

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Jeong, Manhee, and Geehyun Kim. "Development of charge sensitive amplifiers based on various circuit board substrates and evaluation of radiation hardness characteristics." Nuclear Engineering and Technology 52, no. 7 (2020): 1503–10. http://dx.doi.org/10.1016/j.net.2019.12.008.

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Primiceri, P., P. Visconti, A. Melpignano, G. Colleoni, and A. Vilei. "HARDWARE AND SOFTWARE SOLUTION DEVELOPED IN ARM MBED ENVIRONMENT FOR DRIVING AND CONTROLLING DC BRUSHLESS MOTORS BASED ON ST X-NUCLEO DEVELOPMENT BOARDS." International Journal on Smart Sensing and Intelligent Systems 9, no. 3 (2016): 1534–62. http://dx.doi.org/10.21307/ijssis-2017-929.

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Xu, Xiuling, and Jeff S. Friedman. "A Role for the Transcriptional Coactivator PRC1 in Mitochondrial Biogenesis During Erythroid Development." Blood 114, no. 22 (2009): 3642. http://dx.doi.org/10.1182/blood.v114.22.3642.3642.

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Abstract Abstract 3642 Poster Board III-578 Red cell development requires unparalleled mitochondrial metabolic and biosynthetic capacities to support hemoglobin formation. In addition to meeting the energetic requirements of the erythroblast and reticulocyte, mitochondria are the site of multiple steps in heme biosynthesis and are essential for iron utilization. As such, perturbation of mitochondrial function in hematopoietic cells appears to differentially affect red cell development. For instance, we show that the drug chloramphenicol (an inhibitor of mitochondrial protein synthesis) prefere

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Jobin, Jean-François. "Étude de certains aspects du droit nucléaire canadien." Articles 22, no. 2 (2005): 347–70. http://dx.doi.org/10.7202/042440ar.

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The law respecting nuclear energy has to date been the subject of relatively few studies in Canada. Considering, however, the growing importance of nuclear energy as a new or additional form of energy, besides oil, gas, coal and hydroelectric power, and on the other hand, the increase in public concern about the possible consequences of the nuclear option, especially on health and the environment, this area of law is undoubtedly bound to experience a major development. The purpose of the present article is to study existing federal legislation on the matter, as well as its effects on certain p

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Feron, Delphine, Cathy Charlier, Victor Gourain, et al. "Chronic Viral Infection, Virus-Specific Monoclonal Immunoglobulin, and Development of Plasma Cell Malignancy." Blood 118, no. 21 (2011): 2875. http://dx.doi.org/10.1182/blood.v118.21.2875.2875.

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Abstract Abstract 2875 Background: Chronic infection by B-cell tropic viruses can lead to B-cell malignancy via the direct transformation of infected B-lymphocytes or indirectly via cell transformation consecutive to chronic antigen-driven stimulation. In the context of infection by Hepatitis C virus (HCV), the monoclonal immunoglobulin (Ig mc) that arise are typically directed against the virus (Blood 2008; 112 :4357). Moreover, the two mechanisms may occur simultaneously (New Engl J Med 2003; 348 :178). Here we studied 11 patients diagnosed with monoclonal Ig of undetermined significance (MG

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Chung, Jaewook, Xia Zhang, Bruce Collins, et al. "High mobility group A2 (HMGA2) deficiency in pigs leads to dwarfism, abnormal fetal resource allocation, and cryptorchidism." Proceedings of the National Academy of Sciences 115, no. 21 (2018): 5420–25. http://dx.doi.org/10.1073/pnas.1721630115.

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Expression of HMGA2 is strongly associated with body size and growth in mice and humans. In mice, inactivation of one or both alleles of Hmga2 results in body-size reductions of 20% and 60%, respectively. In humans, microdeletions involving the HMGA2 locus result in short stature, suggesting the function of the HMGA2 protein is conserved among mammals. To test this hypothesis, we generated HMGA2-deficient pigs via gene editing and somatic cell nuclear transfer (SCNT). Examination of growth parameters revealed that HMGA2−/+ male and female pigs were on average 20% lighter and smaller than HMGA2

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BOUCHET, F. R. "THE PLANCK SATELLITE: STATUS & PERSPECTIVES." Modern Physics Letters A 22, no. 25n28 (2007): 1857–63. http://dx.doi.org/10.1142/s0217732307025078.

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I review the status of development of the PLANCK project which is slated for launch mid-2008. In particular, I illustrate the type of scientific results to expect in light of the current knowledge of the two on-board instruments. Indeed both instruments have now been delivered to industry for integration and they have been fully tested. This leads us to anticipate that the steady and fast rate of progress enjoyed by cosmology, in particular through the constraints given by the analysis of the Cosmic Microwave background (CMB) will continue unabated in the years to come.

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Loughery, Brian, Dennis Chan, Jay Burmeister, and Michael Dominello. "Development of an in vivo technique for dose verification at the prone breast board / skin interface." Journal of Applied Clinical Medical Physics 22, no. 4 (2021): 202–6. http://dx.doi.org/10.1002/acm2.13229.

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Dittrich, Tobias, Martin Schorb, Isabella Haberbosch, et al. "High-Throughput Immunofluorescence and Electron Tomography to Characterize Centrosomal Aberrations in Plasma Cell Neoplasia." Blood 134, Supplement_1 (2019): 3077. http://dx.doi.org/10.1182/blood-2019-130713.

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Introduction Genomic instability is the basic prerequisite for a Darwinian-type evolution of neoplasia and as such represents a fundamental hallmark of cancer. Centrosomal aberrations have been identified as potent drivers of genomic instability (Cosenza et al., Cell Reports 2017; Krämer et al., Leukemia 2003). The current standard to investigate centrosomal aberrations in cancer patients is immunofluorescence (IF) staining. Although this method is fast and easily scalable, its diagnostic significance is controversially discussed. Moreover, ultrastructural analysis of centrosomes in cancer pat

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Price, Neil, and Neil Thomas. "Continuity and change in the Gwembe Tonga family and their relevance to demography's nucleation thesis." Africa 69, no. 4 (1999): 510–34. http://dx.doi.org/10.2307/1160873.

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AbstractRecent criticisms of demographic theory and methodology have pointed, inter alia, to the need to take on board advances in cognate disciplines. This case study of the Gwembe Valley Tonga of Zambia highlights the important methodological contribution that social anthropology can make to the sub-discipline of family demography. It provides evidence of the empirical invalidity of the ‘family nucleation’ paradigm, which holds that a shift towards conjugal marriage and nuclear household residence patterns is an inevitable consequence of globalisation, and a precursor of the social and econo

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Jakubowiak, Andrzej, Jagoda Jasielec, Cara A. Rosenbaum, et al. "Phase 1 MMRC Trial of Selinexor, Carfilzomib (CFZ), and Dexamethasone (DEX) in Relapsed and Relapsed/Refractory Multiple Myeloma (RRMM)." Blood 126, no. 23 (2015): 4223. http://dx.doi.org/10.1182/blood.v126.23.4223.4223.

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Abstract Background There is an increasing number of multiple myeloma patients (pts) refractory to currently available drugs, including the proteasome inhibitors bortezomib and Carfilzomib (CFZ), necessitating development of novel effective therapeutics. Pre-clinical evaluation of selinexor, a novel orally available selective inhibitor of nuclear export (SINE), in human myeloma cell lines (HMCL), primary plasma cells derived from myeloma patients, and HMCL tumor-bearing mice demonstrated synergistic myeloma cell death with CFZ (Rosebeck et al. ASH 2013) and the ability to overcome resistance t

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