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1

Amareshwar, Shabada Nikhat Fatima Humera Badar Syeda Saba Sultana. "DETERMINATION OF PAZOPANIB HYDROCHLORIDE IN SOLID DOSAGE FORM BY RP-HPLC METHOD: DEVELOPMENT AND VALIDATION." Indo American Journal of Pharmaceutical Sciences 04, no. 11 (2017): 4094–99. https://doi.org/10.5281/zenodo.1048471.

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A simple, accurate, precise, sensitive and stability indicating RP-HPLC method has been developed for the determination of Pazopanib hydrochloride in bulk drug and pharmaceutical dosage form, in which separations are done using develosil C18, 5μm, 150 × 4.6mm i.d. column at a flow rate of 1.0mL/min with an injection volume of 20μL. The beer’s law was obeyed over the concentration range of 5 - 35μg/mL. The correlation coefficient was found to be 0.996 and it showed good linearity, reproducibility, precision in this concentration range. The aim of this paper was to develop and validate the stabi
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2

Shaikh, Zaheer, Abdul Ahad, Showkat Patel, and Maqdoom Farooqui. "Development & Validation of HPLC method for simultaneous estimation of Drotaverine & Omeprazole." International Journal of ChemTech Research 13, no. 1 (2020): 1–10. http://dx.doi.org/10.20902/ijctr.2019.130101.

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A simple and accurate method was developed for simultaneous estimation of Drotaverine & Omeprazole. The chromatography parameters includes stainless steel column Develosil ODS HG-5 RP C18, 5m, 15cmx4.6mm i.d and acetonitrile: potassium dihydrogen phosphate buffer (0.02M, pH 3.0) (55:45v/v) as mobile phase at a flow rate (1.0 ml/minute). The determinations were performed using UV-Vis detector set at 273 nm. The developed HPLC method showed specificity and selectivity with good precision and accuracy, which makes it very suitable for quantification of Drotaverine & Omeprazole.
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3

Tan, Juan, Li Shenghua, Junying Zeng, and Xianjin Wu. "Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius." Bangladesh Journal of Pharmacology 10, no. 4 (2015): 779. http://dx.doi.org/10.3329/bjp.v10i4.23496.

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<p class="Abstract">The total flavonoids of <em>Indocalamus latifolius</em> were evaluated in term of their anti-oxidant and hepatoprotective activities. The results showed that<em> in vitro</em> hepatoprotective and anti-oxidant activities of total flavonoids at doses of 200 and 400 mg/kg and 100 mg/kg, respectively, were comparable to those of the known hepatoprotective drug silymarin at 100 mg/kg. These data were supplemented with histopathological studies of rat liver sections. Seven of the main flavonoid compounds purified by column chromatography using silic
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4

Baranowska, Irena, Sylwia Magiera, and Jacek Baranowski. "Use of multivariate statistical techniques to optimize the separation of isoflavones by liquid chromatography." Open Chemistry 9, no. 6 (2011): 972–81. http://dx.doi.org/10.2478/s11532-011-0093-8.

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AbstractThe aim of this paper is to optimize and validate a high performance liquid chromatography (HPLC) method for separation and quantification of five isoflavones. A statistical central composite design was used to separate all peaks. These multivariate procedures were efficient in determining the optimal separation condition using resolution, capacity factor, asymmetry and number of theoretical plates. The effective separation of the examined compounds was applied on a Develosil RP Aqueous AR 5 RP-30 column with a gradient mobile phase system and a DAD detector. The isolation and preconce
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5

Mamatha, D., G. Naveen, and Devi Singh. "A Validated RP-HPLC Method for Simultaneous Estimation of Ciprofloxacin and Flucionolone in Pharmaceutical Formulation." Indian Journal of Pharmaceutical and Biological Research 6, no. 03 (2018): 48–51. http://dx.doi.org/10.30750/ijpbr.6.3.7.

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A simple, accurate, precise and sensitive RP-HPLC assay method have been validated for the simultaneous estimation of ciprofloxacin and flucionolone in pharmaceutical formulation by RP-HPLC .ciprofloxacin and flucionolone is separated using Develosil ODS HG-5 RP C18, 5μm, 15cmx4.6mm i.d. column at a flow rate of 0.8 ml/ min. Here resolution was good, theoretical plate count and symmetry was appropriate .The LOD and LOQ were calculated using statistical methods. The % RSD values were less than 1.The validation parameters, tested in accordance with the requirements of ICH guidelines, prove the s
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Qureshi, Dr Husna Kanwal, Naaz Fatima, Sumaiya Fatima, Syeda Salwa Fatima Banu, Mohammed Nadeem Uddin, and Syeda Hafsa Noorain. "Stability indicating method development and validation of nitisinone in pure form in marketed pharmaceutical dosage form by using RP-HPLC." International Journal of Multidisciplinary Research and Growth Evaluation 5, no. 4 (2024): 199–205. http://dx.doi.org/10.54660/.ijmrge.2024.5.4.199-205.

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A simple and rapid reverse phase-high performance liquid chromatography (RP-HPLC) method was developed and validated for quantitative determination of Nitisinone in bulk drug and marketed formulations. Nitisinone was analyzed by using reverse phase Develosil ODS HG-5 RP C18, 5µm, 15cmx4.6mm i.d., with mobile phase consisting of Methanol and Phosphate buffer (0.02M, pH-3.6) in the ratio of 45:55%v/v. The flow rate was set 1.0 ml/min and the analysis was performed at wavelength 255 nm using Ultra Violet (UV) detector at ambient temperature. The method was validated according to Guidelines of ICH
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7

Y, Rajesh Babu, and Appalaraju N. "Development and Validation of a Stability Indicating RP-HPLC Method for the Determination of Imatinib Mesylate." International Journal of Current Pharmaceutical Review and Research 8, no. 1 (2017): 56–59. https://doi.org/10.5281/zenodo.12678433.

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The aim of this paper was to develop and validate the stability indicating RP-HPLC method for the determination ofImatinib mesylate in bulk and pharmaceutical dosage forms. A simple, accurate, precise, sensitive and stability indicatingRP-HPLC method has been developed for the determination of Imatinib mesylate in bulk drug and pharmaceutical dosageform, in which separations are done using develosil C18, 5μm, 150 × 4.6mm i.d. column at a flow rate of 1.0mL/min withan injection volume of 20μL. The beer’s law was obeyed over the concentration range of 5 - 35μg/mL. The correl
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8

Suma A.H., Binoy Varghese Cheriyan, Vijey Aanandhi M., and Ramachandran S. "Method Development and Validation of RP-HPLC method for Saxagliptin and Sitagliptin in Pharmaceutical Dosage Form - A Review." International Journal of Research in Pharmaceutical Sciences 12, no. 2 (2021): 1338–44. http://dx.doi.org/10.26452/ijrps.v12i2.4687.

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The study's goal was to develop a plain, quick, and responsive RP-HPLC method for determining the concentrations of Saxagliptin and Sitagliptin in pharmaceutical bulk dosage form (bulk powders). Isocratic elution with Cosmosil C18 (250nm 4.6nm, 5m particle size) and UV detection at 212nm for Saxagliptin and Develosil ODS HG-5 RP-C18 (15cm 4.6mm, 5m particle size) and UV detection at 255nm for Sitagliptin were used in this chromatographic process. Methanol and water (70:30) in a mobile solution with a flow rate of 0.8ml/min for Saxagliptin and (0.05m) phosphate buffer: methanol and water (70:30
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9

Reddy, V. Tejasvi, S. Hari Hara Kumar, M. Akiful Haque, and Vasudha Bakshi. "Method Development and Its Validation for Simultaneous Estimation of Domperidone and Esomeprazole by RP-HPLC in Combination Tablet Dosage Form." INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH 1, no. 01 (2016): 46–55. http://dx.doi.org/10.21477/10.31069/japsr.v1i01.10175.

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A simple and validated reverse phase high performance liquid chromatography (RP-HPLC) method was developed for simultaneous estimation of Esomeprazole and Domperidone. Different HPLC Chromatographic conditions were used to find out the optimum chromatographic condition for best elution of drugs. Good chromatographic separation was achieved on Develosil ODS HG-5 RP C18 (15cmX4.6mm, 5m Particle size), analytical column using a mixture of Potassium dihydrogen phosphate buffer pH: acetonitrile in the ratio of 45:55 v/v used as mobile phase at the flow rate of 1 ml/min and detector wavelength at 2
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10

Reddy, V. Tejasvi, S. Hari Hara Kumar, M. Akiful Haque, and Dr Vasudha Bakshi. "Method Development and Its Validation for Simultaneous Estimation of Domperidone and Esomeprazole by RP-HPLC in Combination Tablet Dosage Form." International Journal of Applied Pharmaceutical Sciences and Research 1, no. 1 (2016): 46. http://dx.doi.org/10.21477/ijapsr/v1i1.10175.

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A simple and validated reverse phase high performance liquid chromatography (RP-HPLC) method was developed for simultaneous estimation of Esomeprazole and Domperidone. Different HPLC Chromatographic conditions were used to find out the optimum chromatographic condition for best elution of drugs. Good chromatographic separation was achieved on Develosil ODS HG-5 RP C18 (15cmX4.6mm, 5mm Particle size), analytical column using a mixture of Potassium dihydrogen phosphate buffer pH: acetonitrile in the ratio of 45:55 v/v used as mobile phase at the flow rate of 1 ml/min and detector wavelength at 2
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11

Chandana, O. S. S., D. Sathis Kumar, and R. Ravichandra Babu. "METHOD DEVELOPMENT AND VALIDATION OF EPROSARTAN MESYLATE AND ITS IMPURITIES USING REVERSE PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY." International Journal of Current Pharmaceutical Research 8, no. 4 (2016): 49. http://dx.doi.org/10.22159/ijcpr.2016v8i4.15277.

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Objective: Our main objective is to develop an accurate and precise RP-HPLC method for the determination of Eprosartan Mesylate and its impurities. Methods: A Develosil ODS UG-5; (150 × 4.6) mm; 5 µm column was used for the Separation of drugs by a mobile phase consisting of Buffer and Acetonitrile mixture in the gradient proportion. The flow rate maintained was 0.8 ml/min and the wavelength used for detection was 235 nm.Results: The linearity was observed in the range of 0.025-50µg/ml of spiked impurities in Eprosartan Mesylate, impurity 1 and impurity 2 with a correlation coefficient of 0.99
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12

Gangadhari, Harika. "An Analytical New RP-HPLC Method Development and Validation for Estimation of Anti-Viral Agent Molnupiravir in Bulk Form and Marketed Pharmaceutical Tablet Dosage Form." International Journal of Pharmacy and Biological Sciences (IJPBS) 13, no. 2 (2023): 190–200. https://doi.org/10.5281/zenodo.10207435.

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AbstractA new, simple, rapid, precise, accurate and reproducible RP-HPLC method for estimation of Molnupiravir in bulk form and marketed formulation. Separation of Molnupiravir was successfully achieved on a Develosil ODS HG-5 RP C18, 5μm, 15cmx4.6mm i.e., column in an isocratic mode of separation utilizing Methanol: Phosphate buffer (0.02M, pH-3.6) in the ratio of 45:55% v/v at a flow rate of 1.0 mL/min and the detection was carried out at 255nm. The method was validated according to ICH guidelines for linearity, sensitivity, accuracy, precision, specificity and robustness. The response was f
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E., Nikhil Chakravarthy. "Novel Method Development and Validation for The Quantitative Estimation of Lenalidomide in Api Form and Marketed Capsule Dosage Form by Using RP-HPLC." International Journal of Pharmacy and Biological Sciences (IJPBS) 14, no. 2 (2024): 43–55. https://doi.org/10.5281/zenodo.12680935.

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AbstractA new, simple, rapid, precise, accurate and reproducible RP-HPLC method for estimation of Lenalidomide in bulk form and marketed formulation. Separation of Lenalidomide was successfully achieved on a Develosil ODS HG-5 RP C18, 5μm, 15cmx4.6mm i.d. column in an isocratic mode of separation utilizing Methanol: Phosphate buffer (0.02M, pH-3.6) in the ratio of 45:55% v/v at a flow rate of 1.0 mL/min and the detection was carried out at 255nm. The method was validated according to ICH guidelines for linearity, sensitivity, accuracy, precision, specificity and robustness. The response was
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14

A., Bheema Naik. "Analytical Method Development and Validation for The Determination of Erlotinib in API Form and Marketed Pharmaceutical Dosage Forms By RP-HPLC." International Journal of Pharmacy and Biological Sciences (IJPBS) 14, no. 1 (2024): 12–23. https://doi.org/10.5281/zenodo.10678159.

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AbstractA new, simple, rapid, precise, accurate and reproducible RP-HPLC method for estimation of Erlotinib in bulk form and marketed formulation. Separation of Erlotinib was successfully achieved on a Develosil ODS HG-5 RP C18, 5μm, 15cmx4.6mm i.d. column in an isocratic mode of separation utilizing Methanol: Phosphate buffer (0.02M, pH-3.6) in the ratio of 45:55% v/v at a flow rate of 1.0 mL/min and the detection was carried out at 255nm. The method was validated according to ICH guidelines for linearity, sensitivity, accuracy, precision, specificity, and robustness. The response was foun
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15

Baranowska, Irena, Sylwia Magiera, and Katarzyna Bortniczuk. "Reverse-phase HPLC method for the simultaneous analysis of triclosan and triclocarban in surface waters." Water Supply 10, no. 2 (2010): 173–80. http://dx.doi.org/10.2166/ws.2010.242.

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A validated reverse-phase HPLC-DAD for the simultaneous determination of triclosan and triclocarban in surface water has been developed, because this method has not been used for determination of these disinfectant agents so far. An isocratic elution was achieved using a Develosil RP Aqueous AR-5 RP-30 column with a flow rate of 1.0 mL min−1. The mobile phase consisted of mixed methanol and water in raito of 90:10, v/v. DAD detector was used to monitor the analytes at 280 nm for triclosan and 265 nm for triclocarban. The time of analysis was 10 min and the retention time for triclosan and tric
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16

Sandya, Rani G* Reshma S. K. Ramadevi S. Naresh D. Aishwarya. "METHOD DEVELOPMENT AND VALIDATION FOR THE QUANTITATIVE ESTIMATION OF PITAVASTATIN IN API FORM AND MARKETED TABLET DOSAGE FORM BY RP-HPLC." Journal of Pharma Research 11, no. 04 (2022): 26–37. https://doi.org/10.5281/zenodo.7027556.

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<strong>ABSTRACT</strong> A new, simple, rapid, precise, accurate and reproducible RP-HPLC method for estimation of Pitavastatin in bulk form and marketed formulation. Separation of Pitavastatin was successfully achieved on a Develosil ODS HG-5 RP C18, 5&mu;m, 15cmx4.6mm i.e. column in an isocratic mode of separation utilizing Methanol: Phosphate buffer (0.02M, pH3.6) in the ratio of 45:55% v/v at a flow rate of 1.0 mL/min and the detection was carried out at 255nm. The method was validated according to ICH guidelines for linearity, sensitivity, accuracy, precision, specificity and robustness.
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17

Viswanath, Pikkili, Doddipalli Venkata Ramana Reddy, and Nagaraju Chamarthi. "Method Development and Validation for the Trace Level Quantification of Genotoxic Impurity Oseltamivir Phosphate Related Compound-a in Oseltamivir Phosphate Using LC-MS." Oriental Journal Of Chemistry 37, no. 5 (2021): 1192–98. http://dx.doi.org/10.13005/ojc/370525.

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A selective and sensitive method has been developed for the determination of ethyl-(3S,4R,5S)-4-acetamido-5-amino-2-azido-3-(pentan-3-yloxy)cyclohexanecarboxylate (OSPRC-A) by using liquid chromatography coupled with mass spectrometer with single mass analyzer (LC-MS).The method was developed by using column DEVELOSIL ODS-UG-5, (50×3.0 mm, 5.0 µm) with linearity range of 0.005% to 0.0151% which meets to quantification level of 150% range. The column oven temperature was maintained at 40ºC. The flow rate was set as 1.5 mL/min. Injection volume was 10 µL and the detection wavelength was 215 nm.
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Jabeen*, Md. Akram Abdul Sayeed. "METHOD DEVELOPMENT, VALIDATION AND STABILITY INDICATING ASSAY PROCEDURE OF PREGABALIN BY USING RP-HPLC." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 03 (2018): 1936–54. https://doi.org/10.5281/zenodo.1212443.

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A simple, rapid and precise Reverse phase liquid chromatographic method has been developed and subsequently validated for estimation of Pregabalin in tablet dosage form. The method is based on High Performance Liquid Chromatography (HPLC) on a reversed-phase column. The separation was carried out using a mobile phase consisting of Phosphate buffer of pH 6.2 and acetonitrile (70:30 v/v). The column used was reversed-phase, Develosil C18, (5&micro;m, 150 x 4.6 mm i.d. column) with flow rate of 1.0 ml/min, column temperature at 40&deg;C using UV detection at 225 nm. The drug was well resolved on
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FIRDAUS, Maulana, Katsumori HATANAKA, Rie MIYAURA, et al. "Key Factors of Sustainable Mariculture Enterprises in Indonesia: Finfish Mariculture Cases From Stakeholder Perspective." International Journal of Conservation Science 14, no. 2 (2023): 685–704. http://dx.doi.org/10.36868/ijcs.2023.02.21.

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Mariculture is a profitable industry in Indonesia and other countries in Southeast Asia in general. The annual outputs of Indonesia's mariculture have been ranked among the tops worldwide. However, unsustainable issues are the main challenges to developin
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Downing, M. A., J. Xiong, A. Eshaghi, A. McGeer, S. N. Patel, and J. Johnstone. "Vancomycin-Variable Enterococcal Bacteremia." Journal of Clinical Microbiology 53, no. 12 (2015): 3951–53. http://dx.doi.org/10.1128/jcm.02046-15.

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Vancomycin-variable enterococcus (VVE) is an emerging pathogen. VVE isolates initially appear phenotypically susceptible to vancomycin but possesses thevanAgene and can developin vitroandin vivoresistance to vancomycin. We report a case of VVE bacteremia and describe how VVE poses diagnostic and therapeutic dilemmas.
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Bishokarma, Suresh, Shikher Shrestha, Kajan Ranabhat, and Rajesh Panth. "Solitary Intracranial Plasmacytoma in an Unusual Location – A Case Report." Nepal Journal of Neuroscience 16, no. 1 (2019): 55–57. http://dx.doi.org/10.3126/njn.v16i1.24436.

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Plasmacytoma is rare form of plasma cell dyscrasias, where there is malignant proliferation of plasma cells. Solitary plasmacytoma developsin isolation without systemic manifestations of multiple myeloma (MM). We report a case of cerebellopontine angle (CPA) plasma cytoma, which masqueraded as a schwannoma with multiple cranial nerve involvement and review a literature pertaining to the same pathological entity.
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S, RAMADOSS, and SIVAPR KASAM K. "ADAPTABILITY OF Macrophomina phaseolina TO QUINTOZENE AND TMTD." Madras Agricultural Journal 74, December (1987): 526–29. http://dx.doi.org/10.29321/maj.10.a02216.

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Macrophomina phaseolina from cowpea develosed resistance to higher concentration of quintozene when serially transferred from media containing quintezone from lower to higher concentrations. On the contrary it did not show any resistance to TMTD. The in- hibition by quintozene at 2000 ppm was 83.88. and 85,52 per cent when M. phaseolina was transferred from lower concentrations of 250, 500 and 1000 ppm respectively as against 91.13 per cent when transferred from control plates.
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AUSTEN, AD, and D. MILES. "INFORMAL DISCUSSION. CONSTRUCTION IN THIRD WORLD COUNTRIES - DEVELOPIN G APPROPRIATE MANAGEMENT SKILLS." Proceedings of the Institution of Civil Engineers 78, no. 6 (1985): 1508–10. http://dx.doi.org/10.1680/iicep.1985.1075.

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Barsukova, A. V., and I. I. Zhukovskiy. "International Activity of the Universitites." MGIMO Review of International Relations, no. 1(28) (February 28, 2013): 66–69. http://dx.doi.org/10.24833/2071-8160-2013-1-28-66-69.

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International cooperation in Academia became a norm. The evolution from sporadic contacts of leading professors for academic and scientific relations to wide cooperation programmes basing on a common values and political mission and aiming to the attraction of human recourses on external markets took a moderate period of time according to the history. Why European Universities cooperate? What are the tasks for cooperation with third countries? How the vector of cooperation between universities systems between Russia and EU have been developin?
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Novokrshchenova, Tatyana S. "MODEL OF DEVELOPIN THE BASIC CULTURE OF UPPER-FORM PUPILS BY MEANS OF MUSEUM ACTIVITIES." Bulletin of the Moscow State Regional University (Pedagogics), no. 4 (2016): 167–75. http://dx.doi.org/10.18384/2310-7219-2016-4-167-175.

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Vimala Asty F.T. Jaya, Vimala Asty F. T. Jaya, Jaehyun Jung, and Jinhwan Oh. "The Impact of Foreign Aid on Gender Inequality in Developin g Countries: Does It Really Work?" GLOBAL BUSINESS FINANCE REVIEW 29, no. 4 (2024): 169–78. http://dx.doi.org/10.17549/gbfr.2024.29.4.169.

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Purpose: This study examines how foreign aid affects gender inequality in developing countries, both at macro (overall) and micro (sectoral) levels. Design/methodology/approach: This study uses comprehensive panel data between 2010 and 2019. Findings: The major findings are: (1) foreign aid, particularly aid targeting women empowerment and gender equal-ity, has significantly contributed to the improvement of gender equality at the macro level except for the least developed countries, (2) at the micro level, gender-targeted aid has significantly improved the share of women in parliament and fem
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Rhamadhan, Fadly, Rachmat Hidayat, Irsan Kahar, and Nurwahidin Hakim. "Shooting Ability Of Petanque Athletes In Palopo: The Role Of Physical Conditions And Kinesthetic Perceptions." JUARA : Jurnal Olahraga 8, no. 1 (2023): 18–24. http://dx.doi.org/10.33222/juara.v8i1.2582.

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Petanque is a relatively new sport in the developin g City of Palopo. However, petanque athletes need help with physical condition aspects that can be seen from the training and competition processes and kinesthetic perception. This research aims to determine the relationship between physical condition and kinesthetic perception of shooting ability. Several physical elements support the shooting in petanque: arm strength, hand-eye coordination, balance and kinesthetic perception. The research results show a significant relationship between physical condition and kinesthetic perception of shoot
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Glithor, R. M., and K. Sylla. "Developin applications for internet telephony: acosemstudy on the use of parlay call control APIs in SIP networks." IEEE Network 18, no. 3 (2004): 48–55. http://dx.doi.org/10.1109/mnet.2004.1301023.

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Tonasa, Muhamad, and Ines Ramadani. "Training In Making Papaya Chips And Tough Chips In Developig Entrepreneurship And Creativity Of The Punggomosi Village Community." Majalah Pengabdian Indonesia 1, no. 3 (2024): 73–77. https://doi.org/10.69616/maindo.v1i3.235.

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The community in Kecamatan Desa/Kelurahan Punggomosi predominantly works as farmers, with papaya being one of the most common crops. Developing papaya into a marketable product is a key part of the KKN (Community Service Program) activities, aimed at broadening the community's knowledge about business and the utilization of local plants, especially for those in need. The program is expected to enhance skills and mental attitudes necessary for personal development. Empowerment through entrepreneurial training serves as a crucial means to provide knowledge and skills related to better family and
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Inuk Wahyuni Istiqomah, Ahmad Firmansyah, Mohamad A’ang Fahrurrozi, et al. "Strategi Pemberian Label Nama Pada Produk Susu Kambing Etawa di Desa Tanjungan, Kemlagi Mojokerto Dalam Upaya Meningkatkan Nilai Jual dan Daya Saing." Jurnal Pengabdian Kepada Masyarakat 4, no. 1 (2025): 32–39. https://doi.org/10.55606/jpkm.v4i1.488.

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Tanjungani Village,i Kemlagi,i hasi greati potentiali asi ai produceri ofi qualityi Etawai goati milk.i However,i thei lacki ofi producti identity,i suchi asi namei labels,i hindersi competitivenessi ini thei market.i thisi communityi servicei aimsi toi developi ai strategyi fori providingi namei labelsi oni Etawai goati milki productsi toi increasei thei sellingi valuei andi attractivenessi ofi thei product.i Thei methodsi usedi includei datai collectioni throughi interviewsi andi observations,i labeli designi basedi oni locali characteristics,i andi marketi testingi toi evaluatei itsi effect
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Saputri, Romadhiyana Kisno, Akhmad Al-Bari, and Ria Indah Kusuma Pitaloka. "Hubungan Status Gizi dan Aktivitas Fisik dengan Kejadian Hipertensi Remaja." Jurnal Gizi 10, no. 2 (2021): 10. http://dx.doi.org/10.26714/jg.10.2.2021.10-19.

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Adolescence is peak height velocity that affect changes in body composition, rapidgrowth on weight, bone mass, pysical activity and nutritional status. Overweight and lack ofphysical activity are risk factors of hyertension in adolescents. Overweight adolescents havea 4,85 times risk of developig hypertension compared to adolescents with normal nutritionalstatus. Lack of physical activity has 7,86 times the risk of developing hypertension thanadolescents with active physical activity. Hypertension in adolescents increase risk ofmorbidity and mortality in adults. This study aim to determine the
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Schneider, Imre. "The role, carrier and mission of neural crest cells in the skin." Bőrgyógyászati és Venerológiai Szemle 97, no. 6 (2021): 326–31. http://dx.doi.org/10.7188/bvsz.2021.97.6.1.

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The neuro crest arising from the ectoderm is a transient structure and disappears as the neurocrest cells leave these places to invade the whole embryo. The epidermis develops from the ectoderm in the fourth embryonal weeks. The embryos consist of cranial-,vagal-, truncal and sacral segments and the neuro crest cells migrate from these places to form various structures, including the peripheral nerve system, the craniofacial bones and cartilages, etc. The neuro crest cells degrade the basal membrane of neural tube and thereafter migrate through the extracellular matrix in ventromedial and dors
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Khosravi, Yalda, Kumutha Malar Vellasamy, Vanitha Mariappan, Shet-Lee Ng, and Jamuna Vadivelu. "Antimicrobial Susceptibility and Genetic Characterisation ofBurkholderia pseudomalleiIsolated from Malaysian Patients." Scientific World Journal 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/132971.

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Burkholderia pseudomallei, the causative agent of melioidosis, is intrinsically resistant to many antibiotics. Ceftazidime (CAZ), the syntheticβ-lactam, is normally used as the first-line antibiotic therapy for treatment of melioidosis. However, acquired CAZ resistance can developin vivoduring treatment with CAZ, leading to mortality if therapy is not switched to a different antibiotic(s) in a timely manner. In this study, susceptibilities of 81B. pseudomalleiisolates to nine different antimicrobial agents were determined using the disk diffusion method, broth microdilution test and Etest. Hig
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Lopes, Susana P., Nuno F. Azevedo, and Maria O. Pereira. "Emergent Bacteria in Cystic Fibrosis:In VitroBiofilm Formation and Resilience under Variable Oxygen Conditions." BioMed Research International 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/678301.

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Concurrent to conventional bacterial pathogens, unusual microbes are emerging from cystic fibrosis (CF) airways. Nonetheless, little is known about the contribution of these newly microbes to the resilience of CF-associated biofilms, particularly under variable-oxygen concentrations that are known to occurin vivoin the mucus of CF patients. Two CF-emergent bacterial species,Inquilinus limosusandDolosigranulum pigrum, and the major pathogenPseudomonas aeruginosawere studied in terms of biofilm development and antibiotic susceptibilities underin vitroatmospheres with different oxygen availabilit
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Jang, Da hye, and Woo Jeong Cho. "IPA on the 4Ps of Marketi ng Mi x for Developi ng Mari ne Lei sure Tourism in South Korea." GLOBAL BUSINESS FINANCE REVIEW 23, no. 3 (2018): 27–37. http://dx.doi.org/10.17549/gbfr.2018.23.3.27.

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36

Aslam, Maleeha. "Burned Alive." American Journal of Islam and Society 23, no. 4 (2006): 128–31. http://dx.doi.org/10.35632/ajis.v23i4.1591.

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Burned Alive is the true story of Souad, a young Palestinian woman whosurvived an attempted honor killing carried out by her brother-in-law. Thisautobiography, documented by Marie-Thérèse Cuny and translated fromthe French by Judith S. Armbruster, is narrated in such a way that the readerscan develop a familiarity with the complicated dimension of genderroles, the prevalence of asymmetrical standards of male and female morality in misogynistic societies, and their impact on women. The plot developsin a way designed to inform the reader that honor killing, although outwardlypracticed as a custo
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Perez-Cabezas, Veronica, Carmen Ruiz-Molinero, Jose Jesus Jimenez-Rejano, Gloria Gonzalez-Medina, Alejandro Galan-Mercant, and Rocio Martin-Valero. "Continuous Positive Airway Pressure Treatment in Patients with Alzheimer’s Disease: A Systematic Review." Journal of Clinical Medicine 9, no. 1 (2020): 181. http://dx.doi.org/10.3390/jcm9010181.

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Background: Epidemiological studies have suggested a pathophysiological relationship between obstructive sleep apnea syndrome (OSAS) and Alzheimer’s disease (AD). The aim of this study is to evaluate the treatment of obstructive sleep apnea with continuous positive airway pressure (CPAP) in AD and its relationship with neurocognitive function improvement. Methods: Systematic review conducted following PRISMA’s statements. Relevant studies were searched in MEDLINE, PEDro, SCOPUS, PsycINFO, Web of Science, CINAHL and SportDicus. Original studies in which CPAP treatment was developel in AD patien
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Dyugovskaya, Larissa, Slava Berger, Andrey Polyakov, Peretz Lavie, and Lena Lavie. "Intermittent Hypoxia Affects the Spontaneous DifferentiationIn Vitroof Human Neutrophils into Long-Lived Giant Phagocytes." Oxidative Medicine and Cellular Longevity 2016 (2016): 1–17. http://dx.doi.org/10.1155/2016/9636937.

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Previously we identified, for the first time, a new small-size subset of neutrophil-derived giant phagocytes (Gϕ) which spontaneously developin vitrowithout additional growth factors or cytokines. Gϕare CD66b+/CD63+/MPO+/LC3B+and are characterized by extended lifespan, large phagolysosomes, active phagocytosis, and reactive oxygen species (ROS) production, and autophagy largely controls their formation. Hypoxia, and particularly hypoxia/reoxygenation, is a prominent feature of many pathological processes. Herein we investigated Gϕformation by applying various hypoxic conditions. Chronic interm
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Mohamed, Ruba, and Abdul Shakoor Chaudhry. "Methods to study degradation of ruminant feeds." Nutrition Research Reviews 21, no. 1 (2008): 68–81. http://dx.doi.org/10.1017/s0954422408960674.

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Ruman degradation is crucial in the supply of dietary nutrients to meet the nutrient demands of the anaerobic microbes and body tissues of ruminant animals. Therefore, it is essential to study the dynamics of rumen degradation of various feeds before their potential use to formulate nutritious diets for ruminant animals. Amongst many methods that have been used in the past, thein saccomethod has been the most effective method to study rumen degradation. However, this method is undesirable due to its implications for animal welfare and costs. While manyin vitromethods have been tested as possib
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Chau, Jennifer Y., Caitlin M. Tiffany, Shilpa Nimishakavi, et al. "Malaria-Associated l-Arginine Deficiency Induces Mast Cell-Associated Disruption to Intestinal Barrier Defenses against Nontyphoidal Salmonella Bacteremia." Infection and Immunity 81, no. 10 (2013): 3515–26. http://dx.doi.org/10.1128/iai.00380-13.

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ABSTRACTCoinfection with malaria and nontyphoidalSalmonellaserotypes (NTS) can cause life-threatening bacteremia in humans. Coinfection with malaria is a recognized risk factor for invasive NTS, suggesting that malaria impairs intestinal barrier function. Here, we investigated mechanisms and strategies for prevention of coinfection pathology in a mouse model. Our findings reveal that malarial-parasite-infected mice, like humans, developl-arginine deficiency, which is associated with intestinal mastocytosis, elevated levels of histamine, and enhanced intestinal permeability. Prevention or rever
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Nisrina, Dinda, and Hasan Maulahela. "Diarrhea as a Prognostic Factor for Severe COVID-19." Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy 23, no. 2 (2022): 266–71. http://dx.doi.org/10.24871/2322022266-271.

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In March of 2020, the WHO has declared the state pandemic of COVID-19 that started in the city of Wuhan, China. The widespread of cases resulted in 2,877,476 cases and 73,582 death reported in Indonesia. It is commonly known that the respiratory system was the main problem in COVID-19, but it is recently reported that gastrointestinal involevment has a higher likelihood to develop into severe cases. Moreover, it is found that diarrhea is the most highly prevalent of the gastrointestinal signs and symptoms in COVID-19 patients. The aim of this evidence-based case report is to understand the ass
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Suwitra Wirya, I. Made, I. Made Bayu Wisnawa, and I. Gusti Agung Bagus Widiantara. "Management Of Teba Majelangu As Educational Tourism in Denpasar City." Jurnal Manajemen Pelayanan Hotel 8, no. 1 (2024): 242. http://dx.doi.org/10.37484/080114.

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One of the natural, cultural and educational tourist attractions of Denpasar City is Subak TeBA MajelanguEducational Tourism. However, the number of tourists who come to this place is still very low compared toother tourist attractions in Denpasar City. Thus, the manager must make efforts to develop a strategy so thatthe attraction of Subak TeBA Majelangu Educational Tourism becomes an educational tourist attraction in thecity of Denpasar in the most effective way. Therefore, the purpose of this article is to find out the strategies thatare carried out so that Subak TeBA Majelangu Educational
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Hutsol, Kyrylo. "ARTIFICIAL INTELLIGENCE AS A RESOURCE FOR DEVELOPING PERSONAL LIFE COMPETENCE IN THE CONTEXT OF WAR IN UKRAINE." Мiждисциплiнарнi дослiдження складних систем, no. 24 (December 26, 2024): 97–114. https://doi.org/10.31392/iscs.2024.24.097.

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The aim of the article is to characterize the main functi-ons, implementation methods, and limitations of artificial intelligence (AI) as a resource for developing personal life competence during the war in Ukraine, based on the concept of understanding AI’s potential. The article identifies the possibilities of using AI to support informati-onal and psychological assistance, social-psychological adaptation, and innovative-prognostic support in the context of three key dimensions of life competence development: routine-selective, adaptive, and innovative. It is shown that the routine-selective
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44

Bock, Udo, Von Deylen D, Jochner M, Doerr M, Stäbler C, and Reichl S. "Development of In Vitro Methodologies to Investigate Binding by Sodium Hyaluronate in Eye Drops to Corneal Surfaces." Open Ophthalmology Journal 12, no. 1 (2018): 226–40. http://dx.doi.org/10.2174/1874364101812010226.

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Purpose:To developin vitromethods to assess binding by sodium hyaluronate in eye drops to corneal surfaces.Methods:Two different, complementary corneal binding set-ups were developed. In a dynamicin vitromodel, confluent corneal epithelial cells (HCE-T) were assembled in chamber slides and a declining channel. A static model was constructed withex vivoporcine corneas clamped in Franz cells. To test the predictive capacity of models, four different eye drops containing sodium hyaluronate were spiked with tritium-labeled sodium hyaluronate to standardize quantification. In both settings, eye dro
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Dudnik, Alexey V., and Tatyana A. Cherdakova. "Investment Strategies for Increasing the Agribusiness Competitiveness." Economy of Region 17, no. 2 (2021): 632–43. http://dx.doi.org/10.17059/ekon.reg.2021-2-20.

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Nowadays, investment in national agri-food systems is of significant interest, as it is a necessary condition for implementing large-scale technological innovations which are crucial not only for this particular system, but for Russian economy in general. The research aims to study how investments affect the competitiveness of the Russian agri-food system and to propose a conceptual framework for strategic agribusiness management at the regional and national levels. We hypothesise that competitiveness indicators, including cost intensity of production, depend on the investment in agribusiness.
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Ocenia, Yolanda, Yusmini Yusmini, and Susy Edwina. "Analysis of Financial Feasibility System Integration of Cow and Palm Oil with A Semi Intensive Maintenance System (Case Study on Sarwo Sari Farmer Group at Sari Makmur Village Pangkalan Lesung District Pelalawan Regency)." Journal of Agribusiness and Community Empowerment 2, no. 2 (2019): 49–57. http://dx.doi.org/10.32530/jace.v2i2.71.

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This research aims to analyze the financial feasibility and sensitivity to changes in input prices, production levels and prices of the output of a business System integration of Cow-Palm oil in Sari Makmur villagePangkalan Lesung District Pelalawan Regency Province of Riau. The research method used is the method of case studies. Data used are primary data and secondary data. The informant on this research consists of a group of farmers which is Sari Sarwo group members as many as 14 people and the number of cattle beginning as many as 51 cows , extension officers of Sari Makmur village, Villa
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Khair, Mohammad, and Abedullah Alsofiani. "The Impact of Teaching Mathematics by Using an Active Learning-Based Strategy on Developin g Systemic Thinking Skills of Intermediate Stage Students in Taif Governorate- Saudi Arabia." International Journal for Talent Development 8, no. 1 (2017): 93–120. http://dx.doi.org/10.20428/ijtd.8.1.5.

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Elfiadi, Elfiadi, and Desiva Munasti. "Pengembangan Motorik Kasar melalui Kegiatan Senam Kreasi pada Anak PAUD Balai Pengajian Baitul Ishlah Lhokseumawe." Ibrah: Jurnal Pengabdian kepada Masyarakat 1, no. 1 (2022): 1–12. http://dx.doi.org/10.47766/ibrah.v1i1.1127.

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This study aims to develop children's gross motor skills through creative gymnastics activities at the Baitul Ishlah Lhokseumawe Study Center. The type of research used is classroom action research. The technique of collecting data using interviews, observation, and documentation with qualitative descriptive data analysis techniques. The results showed that creative gymnastics activities can develop gross motor skills of the children in the Baitul shlah Lhokseumawe Research Center. Cycle I show the gross motor development of children who have not developed as many as 4 children or 11 children
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Choi, Young-Ho, Pablo Ross, Isabel C. Velez, B. Macías-García, Fernando L. Riera, and Katrin Hinrichs. "Cell lineage allocation in equine blastocysts produced in vitro under varying glucose concentrations." REPRODUCTION 150, no. 1 (2015): 31–41. http://dx.doi.org/10.1530/rep-14-0662.

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Equine embryos developin vitroin the presence of high glucose concentrations, but little is known about their requirements for development. We evaluated the effect of glucose concentrations in medium on blastocyst development after ICSI. In experiment 1, there were no significant differences in rates of blastocyst formation among embryos cultured in our standard medium (DMEM/F-12), which contained &gt;16 mM glucose, and those cultured in a minimal-glucose embryo culture medium (&lt;1 mM; Global medium, GB), with either 0 added glucose for the first 5 days, then 20 mM (0-20) or 20 mM for the en
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Elango, Rajavel, Crystal Levesque, Ronald O. Ball, and Paul B. Pencharz. "Available versus digestible amino acids – new stable isotope methods." British Journal of Nutrition 108, S2 (2012): S306—S314. http://dx.doi.org/10.1017/s0007114512002498.

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The nutritive value of food protein sources is dependent on the amino acid composition and the bioavailability of the nutritionally indispensable amino acids. Traditionally the methods developed to determine amino acid bioavailability have focused on intestinal absorption or digestibility, which is calculated as the percent of amino acid intake that does not appear in digesta or faeces. Traditional digestibility based methods do not always account for gut endogenous amino acid losses or absorbed amino acids which are unavailable due to the effect of heat processing and the presence of anti-nut
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