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1

Papakonstantinou, Georgios I., Dimitrios A. Gougoulis, Nikolaos Voulgarakis, et al. "Effects of Injectable Administration of Dexamethasone Alone or in Combination with Vitamin E/Se in Newborn Low Birth Weight Piglets." Veterinary Sciences 10, no. 2 (2023): 135. http://dx.doi.org/10.3390/vetsci10020135.

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Increasing litter size may lead to low-birth-weight piglets (LBW) and further negative long-term effects. This study aimed to evaluate the effects of intramuscular administration (IM) of dexamethasone (Dexa) alone or in combination with vitamin E/Se on LBW piglets during the early postnatal period. The study included a total of 100 LBW piglets that were divided into 5 groups (20 LBW piglets per group) and treated with IM Dexa alone or in combination with vitamin E/Se (Vit E/Se) after birth as follows: (a) Group A-Cont: Control group, (b) Group B-Dexa1: Dexa on D1 (1st day of life), (c) Group C
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Börner, Wilhelm. "DEXA." JAMA: The Journal of the American Medical Association 268, no. 4 (1992): 474. http://dx.doi.org/10.1001/jama.1992.03490040050022.

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Borner, W. "DEXA." JAMA: The Journal of the American Medical Association 268, no. 4 (1992): 474–75. http://dx.doi.org/10.1001/jama.268.4.474.

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4

Kellie, Shirley E. "DEXA-Reply." JAMA: The Journal of the American Medical Association 268, no. 4 (1992): 475. http://dx.doi.org/10.1001/jama.1992.03490040048023.

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5

Lim, So-Jung, Hyun-Jin Kim, Hansik Kim, et al. "Skeletal Muscle Atrophy Induced by Dexamethasone Is Attenuated by Amino Acid Complex Supplementation in Rats." Life 15, no. 4 (2025): 517. https://doi.org/10.3390/life15040517.

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Muscle atrophy, a physiological decline in muscle mass and strength due in ageing, occurs through an imbalance between protein breakdown and synthesis. The purpose of this study was to verify whether amino acid complex supplementation (ACS) can prevent and treat muscle loss in a dexamethasone (Dexa, 800 μg/kg)-induced rat model of sarcopenia. Sprague Dawley rats (6 weeks old) were assigned to seven groups: (i) normal control, (ii) positive control (high-dose ACS, 500 mg), (iii) Dexa only, (iv) Dexa + high-dose ACS (500 mg), (v) Dexa + medium-dose ACS (300 mg), (vi) Dexa + low-dose ACS (100 mg)
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Oh, Seyeon, Chang Hu Choi, Bae-Jin Lee, Joung-Hyun Park, Kuk-Hui Son, and Kyunghee Byun. "Fermented Oyster Extract Attenuated Dexamethasone-Induced Muscle Atrophy by Decreasing Oxidative Stress." Molecules 26, no. 23 (2021): 7128. http://dx.doi.org/10.3390/molecules26237128.

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It is well known that oxidative stress induces muscle atrophy, which decreases with the activation of Nrf2/HO-1. Fermented oyster extracts (FO), rich in γ-aminobutyric acid (GABA) and lactate, have shown antioxidative effects. We evaluated whether FO decreased oxidative stress by upregulating Nrf2/HO-1 and whether it decreased NF-κB, leading to decreased IL-6 and TNF-α. Decreased oxidative stress led to the downregulation of Cbl-b ubiquitin ligase, which increased IGF-1 and decreased FoxO3, atrogin1, and Murf1, and eventually decreased muscle atrophy in dexamethasone (Dexa)-induced muscle atro
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Touil, Nassim, Athanassia Pavlopoulou, Simon Delande, et al. "Effect of Intravenous Dexamethasone Dose on the Occurrence of Rebound Pain after Axillary Plexus Block in Ambulatory Surgery." Journal of Clinical Medicine 12, no. 13 (2023): 4310. http://dx.doi.org/10.3390/jcm12134310.

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Rebound pain (RP) remains a challenge in ambulatory surgery, characterized by severe pain upon resolution of a peripheral nerve block (PNB). Intravenous (IV) administration of Dexamethasone (DEXA) potentiates PNB analgesic effect and reduces RP incidence although preventive effective dose remains undetermined. This retrospective analysis evaluates the preventive effect of IV DEXA on RP in outpatients undergoing upper limb surgery under axillary block. DEXA was divided into high (HD > 0.1 mg/kg) or low (LD < 0.1 mg/kg) doses. RP was defined as severe pain (NRS ≥ 7/10) within 24 h of PNB r
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Blake, G. M. "Replacing DEXA scanners." Nuclear Medicine Communications 16, no. 4 (1995): 237. http://dx.doi.org/10.1097/00006231-199504000-00101.

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9

Lambert, Brad S., Jonathan M. Oliver, Gilbert R. Katts, John S. Green, Steven E. Martin, and Stephen F. Crouse. "DEXA or BMI." Clinical Journal of Sport Medicine 22, no. 5 (2012): 436–38. http://dx.doi.org/10.1097/jsm.0b013e31825d5d65.

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Levine, James A., Lana Abboud, Mitchel Barry, Judd E. Reed, Patrick F. Sheedy, and Michael D. Jensen. "Measuring leg muscle and fat mass in humans: comparison of CT and dual-energy X-ray absorptiometry." Journal of Applied Physiology 88, no. 2 (2000): 452–56. http://dx.doi.org/10.1152/jappl.2000.88.2.452.

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Dual-energy X-ray absorptiometry (DEXA) is reported to be inferior to computed tomography (CT) to measure changes in appendicular soft tissue composition. We compared CT- and DEXA-measured thigh muscle and fat mass to evaluate the random and systematic discrepancies between these two methods. Thigh skeletal muscle area (single-slice CT) was suboptimally ( r 2= 0.74, P < 0.0001) related to DEXA-measured thigh fat-free mass (FFM). In contrast, thigh muscle and adipose tissue volumes (multislice CT) were highly related to DEXA-measured thigh FFM and fat (both r 2 = 0.96, P < 0.0001). DEXA-m
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Musee, Ndeke, Lemme Prica Kebaabetswe, Shepherd Tichapondwa, et al. "Occurrence, Fate, Effects, and Risks of Dexamethasone: Ecological Implications Post-COVID-19." International Journal of Environmental Research and Public Health 18, no. 21 (2021): 11291. http://dx.doi.org/10.3390/ijerph182111291.

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The recent outbreak of respiratory syndrome-coronavirus-2 (SARS-CoV-2), which causes coronavirus disease (COVID-19), has led to the widespread use of therapeutics, including dexamethasone (DEXA). DEXA, a synthetic glucocorticoid, is among the widely administered drugs used to treat hospitalized COVID-19 patients. The global COVID-19 surge in infections, consequent increasing hospitalizations, and other DEXA applications have raised concerns on eminent adverse ecological implications to aquatic ecosystems. Here, we aim to summarize published studies on DEXA occurrence, fate, and effects on orga
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Aldaz, Paula, Jaione Auzmendi-Iriarte, Maika Durántez, et al. "Identification of a Dexamethasone Mediated Radioprotection Mechanism Reveals New Therapeutic Vulnerabilities in Glioblastoma." Cancers 13, no. 2 (2021): 361. http://dx.doi.org/10.3390/cancers13020361.

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(1) Background: Despite the indisputable effectiveness of dexamethasone (DEXA) to reduce inflammation in glioblastoma (GBM) patients, its influence on tumour progression and radiotherapy response remains controversial. (2) Methods: We analysed patient data and used expression and cell biological analyses to assess effects of DEXA on GBM cells. We tested the efficacy of tyrosine kinase inhibitors in vitro and in vivo. (3) Results: We confirm in our patient cohort that administration of DEXA correlates with worse overall survival and shorter time to relapse. In GBM cells and glioma stem-like cel
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Oh, Seyeon, Jinyoung Yang, Chulhyun Park, Kukhui Son, and Kyunghee Byun. "Dieckol Attenuated Glucocorticoid-Induced Muscle Atrophy by Decreasing NLRP3 Inflammasome and Pyroptosis." International Journal of Molecular Sciences 22, no. 15 (2021): 8057. http://dx.doi.org/10.3390/ijms22158057.

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Dexamethasone (Dexa), frequently used as an anti-inflammatory agent, paradoxically leads to muscle inflammation and muscle atrophy. Receptor for advanced glycation end products (RAGE) and Toll-like receptor 4 (TLR4) lead to nucleotide-binding oligomerization domain-like receptor pyrin domain containing 3 (NLRP3) inflammasome formation through nuclear factor-κB (NF-κB) upregulation. NLRP3 inflammasome results in pyroptosis and is associated with the Murf-1 and atrogin-1 upregulation involved in protein degradation and muscle atrophy. The effects of Ecklonia cava extract (ECE) and dieckol (DK) o
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Chrysis, Dionisios, Farasat Zaman, Andrei S. Chagin, Masaharu Takigawa, and Lars Sävendahl. "Dexamethasone Induces Apoptosis in Proliferative Chondrocytes through Activation of Caspases and Suppression of the Akt-Phosphatidylinositol 3′-Kinase Signaling Pathway." Endocrinology 146, no. 3 (2005): 1391–97. http://dx.doi.org/10.1210/en.2004-1152.

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Although glucocorticoids are known to induce apoptosis in chondrocytes, the mechanisms for this effect and the potential antiapoptotic role of IGF-I are unknown. To address this, we studied the effects of dexamethasone (Dexa) on apoptosis in the HCS-2/8 chondrocytic cell line. Dexa (25 μm) increased apoptosis (cell death ELISA) by 39% and 45% after 48 and 72 h, respectively (P < 0.01 and P < 0.05, respectively). IGF-I (100 ng/ml) decreased Dexa-induced apoptosis to levels similar to control cells. Apoptosis was associated with cleavage of poly-ADP-ribose polymerase (PARP) and α-f
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15

Hong, Boohwi, Chahyun Oh, Yumin Jo, et al. "The Effect of Intravenous Dexamethasone and Dexmedetomidine on Analgesia Duration of Supraclavicular Brachial Plexus Block: A Randomized, Four-Arm, Triple-Blinded, Placebo-Controlled Trial." Journal of Personalized Medicine 11, no. 12 (2021): 1267. http://dx.doi.org/10.3390/jpm11121267.

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Intravenous dexamethasone and dexmedetomidine, in conjunction with peripheral nerve blockade, have each been reported to prolong the duration of analgesia. This study tested whether combined use further prolongs analgesia duration after supraclavicular brachial plexus block (BPB) in patients undergoing orthopedic upper extremity surgery. One hundred twenty patients were randomized 1:1:1:1 to Control (saline bolus and midazolam infusion [0.05 mg/kg loading, 20 µg/kg/h thereafter]); DMED (saline bolus and dexmedetomidine infusion [1 μg/kg loading, 0.4 μg/kg/h thereafter]); DEXA (dexamethasone [1
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16

Kumar, Rebecca Nirmal, Mary Clare Masters, and Karen Krueger. "760. Assessment of DEXA Scan Ordering Among Infectious Disease Providers at a Large Tertiary-Care Urban Academic Center in the Midwest." Open Forum Infectious Diseases 6, Supplement_2 (2019): S339. http://dx.doi.org/10.1093/ofid/ofz360.828.

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Abstract Background Osteoporosis is compromised bone strength that predisposes to fracture. It can be diagnosed by Dual-energy x-ray absorptiometry (DEXA) measurement of bone mineral density (BMD). Persons with HIV (PWH) are at higher risk for the development of osteoporosis. As such, the HIV Medicine Association’s (HIVMA) primary care guidelines recommend DEXA screening for all HIV-infected postmenopausal women and men aged ≥50 years. The purpose of this study was to asses the frequency of DEXA utilization within a tertiary-care urban academic center in the Midwest and to identify prevalence
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Muth, Amelie, Nora Philipp, Anetta Marcinek, et al. "Beyond Mitigating Immune-Related Adverse Events: Glucocorticoids Ameliorate Bispecific Antibody-Mediated T-Cell Exhaustion I n Vitro." Blood 142, Supplement 1 (2023): 5389. http://dx.doi.org/10.1182/blood-2023-174258.

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Following the approval of blinatumomab in 2015 T-cell recruiting bispecific antibodies (BsAbs) became the established standard-of-care for relapsed or refractory (r/r) and minimal residual disease positive B-cell precursor acute lymphoblastic leukemia. More recently, there has been a notable increase in the approval of additional BsAb constructs for malignancies such as r/r follicular lymphoma, r/r large B-cell lymphoma, and advanced multiple myeloma (MM), with further approvals anticipated. Despite the clinical success, administration of BsAbs is commonly linked to dose-limiting immune-relate
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18

Kohan, Eitan M., Venu M. Nemani, Stuart Hershman, Daniel G. Kang, and Michael P. Kelly. "Lumbar computed tomography scans are not appropriate surrogates for bone mineral density scans in primary adult spinal deformity." Neurosurgical Focus 43, no. 6 (2017): E4. http://dx.doi.org/10.3171/2017.9.focus17476.

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OBJECTIVEThe authors examined the correlation between lumbar spine CT Hounsfield unit (HU) measurements and bone mineral density measurements in an adult spinal deformity (ASD) population.METHODSPatients with ASD were identified in the records of a single institution. Lumbar CT scans were reviewed, and the mean HU measurements from L1–4 were recorded. Bone mineral density (BMD) was assessed using femoral neck and lumbar spine dual-energy x-ray absorptiometry (DEXA). The number of patients who met criteria for osteoporosis was determined for each imaging modality.RESULTSForty-eight patients und
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Hossain, M. A., J. Park, S. H. Choi, and G. Kim. "Dexamethasone induces apoptosis in proliferative canine tendon cells and chondrocytes." Veterinary and Comparative Orthopaedics and Traumatology 21, no. 04 (2008): 337–42. http://dx.doi.org/10.3415/vcot-07-06-0060.

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SummaryDexamethasone (Dexa) has been commonly used in humans and domestic animals, particularly in the treatment of tendon injuries and cartilage degeneration. However, it is often associated with tendon rupture and impaired tendon and cartilage healing. In the present study, we investigated Dexa’s in vitro effects on the growth of cell proliferation and the induction of apoptosis in canine Achilles tendon cells and chondrocytes. Cell proliferation after treatment with Dexa for two to six days was quantified by a 2,3-bis{2-methoxy- 4-nitro-5-sulfophenyl}-2H-tetrazolium-5-carboxyanilide inner s
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Ozdemir, Burcu, Adalet Altunsoy, mran Hasanoglu, Esragul nc, and Rahmet Guner. "Evaluation of bone mineral density in tenofovir disoproxil fumarate-treated patients with chronic hepatitis B." Annals of Medical Research 30, no. 9 (2023): 1. http://dx.doi.org/10.5455/annalsmedres.2023.05.119.

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Aim: Evaluate the impact of Tenofovir Disoproxil Fumarate (TDF) treatment on bone mineral density (BMD) for patients with chronic hepatitis B (CHB) with Dual X-ray absorptiometry (DEXA) and the Fracture Risk Assessment Tool (FRAX) score. Material and Methods: A total of 38 CHB patients treated with TDF were included in this retrospective study. To estimate BMD, DEXA, demographic details, and laboratory values were examined in patients. The BMD measurements were compared after dividing the patients into 3 groups as normal BMD, osteopenic, and osteoporotic. FRAX scores (before and after DEXA) we
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Visser, Marjolein, Thomas Fuerst, Thomas Lang, et al. "Validity of fan-beam dual-energy X-ray absorptiometry for measuring fat-free mass and leg muscle mass." Journal of Applied Physiology 87, no. 4 (1999): 1513–20. http://dx.doi.org/10.1152/jappl.1999.87.4.1513.

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The aim of the study was to examine the accuracy of fan-beam dual-energy X-ray absorptiometry (DEXA) for measuring total body fat-free mass (FFM) and leg muscle mass (MM) in elderly persons. Participants were 60 men and women aged 70–79 yr and with a body mass index of 17.5–39.8 kg/m2. FFM and MM at four leg regions were measured by using DEXA (Hologic 4500A, v8.21). A four-compartment body composition model (4C) and multislice computed tomography (CT) of the legs were used as the criterion methods for FFM and MM, respectively. FFM by DEXA was positively associated with FFM by 4C ( R 2 = 0.98,
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Ruol, Piero, Barbara Zanuttigh, Luca Martinelli, Peter Kofoed, and Peter Frigaard. "NEAR-SHORE FLOATING WAVE ENERGY CONVERTERS: APPLICATIONS FOR COASTAL PROTECTION." Coastal Engineering Proceedings 1, no. 32 (2011): 61. http://dx.doi.org/10.9753/icce.v32.structures.61.

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Aim of this note is to analyse the possible application of a Wave Energy Converter (WEC) as a combined tool to protect the coast and harvest energy. Physical model tests are used to evaluate wave transmission past a near-shore floating WEC of the wave activated body type, named DEXA. Efficiency and transmission characteristics are approximated to functions of wave height, period and obliquity. Their order of magnitude are 20% and 80%, respectively. It is imagined that an array of DEXA is deployed in front of Marina di Ravenna beach (IT), a highly touristic site of the Adriatic Coast. Based on
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Kohrt, Wendy M. "Preliminary evidence that DEXA provides an accurate assessment of body composition." Journal of Applied Physiology 84, no. 1 (1998): 372–77. http://dx.doi.org/10.1152/jappl.1998.84.1.372.

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Kohrt, Wendy M. Preliminary evidence that DEXA provides an accurate assessment of body composition. J. Appl. Physiol. 84(1): 372–377, 1998.—It was previously found that dual-energy X-ray absorptiometry (DEXA) underestimated central body fat. The purposes of this study were to determine whether an updated version (enhanced version 5.64) of the analysis program corrected this problem ( experiment 1) and to compare body composition assessed by DEXA and hydrodensitometry (HD) in women ( n= 225) and men ( n = 110) across a 21- to 81-yr age range ( experiment 2). For experiment 1, 10 subjects underw
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Brommage, Robert. "Validation and calibration of DEXA body composition in mice." American Journal of Physiology-Endocrinology and Metabolism 285, no. 3 (2003): E454—E459. http://dx.doi.org/10.1152/ajpendo.00470.2002.

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Validated methods of determining murine body composition are required for studies of obesity in mice. Dual-energy X-ray absorptiometry (DEXA) provides a noninvasive approach to assess body fat and lean tissue contents. Similar to DEXA analyses in other species, body fat measurements in mice show acceptable precision but suffer from poor accuracy. Because fat and lean tissues each contain various components, these inaccuracies likely result from selection of inappropriate calibration standards. Analysis of solvents showed that the PIXImus2 DEXA gave results consistent with theoretical calculati
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Rangan, Amar, Stephen P. Tuck, Paul D. Scott, et al. "Prospective comparative study of quantitative X-ray (QXR) versus dual energy X-ray absorptiometry to determine the performance of QXR as a predictor of bone health for adult patients in secondary care." BMJ Open 11, no. 12 (2021): e051021. http://dx.doi.org/10.1136/bmjopen-2021-051021.

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ObjectivesTo evaluate a method of quantitative X-ray (QXR) for obtaining bone health information from standard radiographs aimed at identifying early signs of osteoporosis to enable improved referral and treatment. This QXR measurement is performed by postexposure analysis of standard radiographs, meaning bone health data can be acquired opportunistically, alongside routine imaging.DesignThe relationship between QXR and dual energy X-ray absorptiometry (DEXA) was demonstrated with a phantom study. A prospective clinical study was conducted to establish areal bone mineral density (aBMD) predict
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Igarashi, Shunji, Atsushi Manabe, Akira Ohara, et al. "No Advantage of Dexamethasone Over Prednisolone for the Outcome of Standard- and Intermediate-Risk Childhood Acute Lymphoblastic Leukemia in the Tokyo Children's Cancer Study Group L95-14 Protocol." Journal of Clinical Oncology 23, no. 27 (2005): 6489–98. http://dx.doi.org/10.1200/jco.2005.01.982.

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Purpose To evaluate whether dexamethasone (DEXA) yields a better outcome than prednisolone (PRED) in a prospective, randomized, controlled trial for the treatment of childhood acute lymphoblastic leukemia (ALL). Patients and Methods Two hundred thirty-one standard-risk (SR) patients and 128 intermediate-risk (IR) non–B-cell ALL patients were registered from March 1995 to March 1999. After random assignment in each group, the PRED arm patients received PRED 60 mg/m2 during induction followed by PRED 40 mg/m2 over four intensifications in the SR group and three intensifications in the IR group.
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Alsamarraie, Henin, and Alexandra Clark. "ODP092 Guideline Adherence for Age-based Screening of Osteoporosis in Men at a Veterans Affairs Medical Center." Journal of the Endocrine Society 6, Supplement_1 (2022): A163. http://dx.doi.org/10.1210/jendso/bvac150.335.

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Abstract Background Osteoporosis is one of the leading causes of morbidity and mortality in older women and men. Men with osteoporosis have higher fracture-related morbidity and mortality rates compared to women, but screening rates in men remain much lower. Moreover, there is limited veteran-specific data despite the suggestion that veterans may be at higher risk for osteoporosis. (1) Objective: To assess current dual energy X-ray absorptiometry (DEXA) ordering practices within a veteran cohort. Design: A retrospective cohort study of male veterans aged71-75 years who were evaluated by a prim
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Combest, Travis, James Tufano, Michael Lane, and Jordan Moon. "COMPARISON OF FOUR BODY COMPOSITION METHODS." Journal of Clinical Exercise Physiology 13, s1 (2024): 1. http://dx.doi.org/10.31189/2165-7629-13-s1.1.

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BACKGROUND High-frequency (500Khz) direct segmental multifrequency bioelectrical impedance analysis (BIA) accurately calculates total water mass and body fat% (BF%), but it is unknown whether higher frequencies (1000Khz) increase measurement accuracy. PURPOSE: This study compared BIA 500Khz, BIA 1000Khz, the Department of Defense DoD Circumference Method (CM), and the reference standard DEXA. METHODS A total of 62 participants from the military healthcare system (n=25 males, 38.8±11.4yrs, n=37 females 43.7±15.95yrs) were measured. BF% was estimated via DEXA, BIA 500, BIA 1000, and CM to identi
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Шохобиддинова, Гулираъно. "DEXA: BONE DENSITY SCANNER." MODERN SCIENCE AND RESEARCH 3, no. 4 (2024): 194–96. https://doi.org/10.5281/zenodo.11128034.

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<em>A bone density scan, also called dual-energy X-ray absorptiometry (DEXA) or bone densitometry, is an advanced form of X-ray technology that is used to measure bone loss. </em> <em>DEXA is the current standard for measuring bone mineral density. X-rays help doctors diagnose and treat diseases. It exposes you to a small dose of ionizing radiation to produce images of the inside of your body.</em>
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Wang, Wei, Zimian Wang, Myles S. Faith, Donald Kotler, Rick Shih, and Steven B. Heymsfield. "Regional skeletal muscle measurement: evaluation of new dual-energy X-ray absorptiometry model." Journal of Applied Physiology 87, no. 3 (1999): 1163–71. http://dx.doi.org/10.1152/jappl.1999.87.3.1163.

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Although there is growing interest in studying muscle distribution, regional skeletal muscle (SM) mass measurement methods remain limited. The aim of the present study was to develop a new dual-energy X-ray absorptiometry (DEXA) model for estimating regional adipose tissue-free skeletal muscle mass (AT-free SM). Relationships were derived from Reference Man data between tissue-system- level components (i.e., AT-free SM, AT, skeleton, and skin) and molecular-level components including fat-free soft tissue, fat, and bone mineral. The proposed DEXA-SM model was evaluated by multiscan computerized
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Sauter, Stephanie N., Edgar Ontsouka, Bettina Roffler, et al. "Effects of dexamethasone and colostrum intake on the somatotropic axis in neonatal calves." American Journal of Physiology-Endocrinology and Metabolism 285, no. 2 (2003): E252—E261. http://dx.doi.org/10.1152/ajpendo.00557.2002.

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Glucocorticoids and colostrum feeding influence postnatal maturation of the somatotropic axis. We have tested the hypothesis that dexamethasone (Dexa) affects the somatotropic axis in neonatal calves dependent on colostrum intake. Calves were fed either with colostrum or with a milk-based formula ( n = 14/group), and, in each feeding group, one-half of the calves were treated with Dexa (30 μg · kg body wt-1 · day-1). Pre- and postprandial blood samples were taken on days 1, 2, 4, and 5, and liver samples were taken on day 5 of life. Dexa increased insulin-like growth factor (IGF)-I, but decrea
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Inceu, Andreea Ioana, Maria Adriana Neag, Adrian Catinean, et al. "The Effects of Probiotic Bacillus Spores on Dexamethasone-Treated Rats." International Journal of Molecular Sciences 24, no. 20 (2023): 15111. http://dx.doi.org/10.3390/ijms242015111.

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Glucocorticoids are effective anti-inflammatory and immunosuppressive agents. Long-term exposure is associated with multiple metabolic side effects. Spore-forming probiotic bacteria have shown modulatory properties regarding glycolipid metabolism and inflammation. The aim of this study was to evaluate, for the first time, the effects of Bacillus species spores (B. licheniformis, B. indicus, B. subtilis, B. clausii, and B. coagulans) alone and in combination with metformin against dexamethasone-induced systemic disturbances. A total of 30 rats were randomly divided into 5 groups: group 1 served
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Prayoga, Ibnu, and Wawan Kurniawan. "PENGEMBANGAN SERVER VOIP BERBASIS ASTERISK DAN SHOREWAL MENGGUNAKAN METODE NETWORK DEVELOPMENT LIFE CYLCE." JURNAL SATYA INFORMATIKA 5, no. 2 (2023): 59–66. http://dx.doi.org/10.59134/jsk.v5i2.388.

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PT Dexa Medica merupakan perusahaan yang bergerak di bidang farmasi dan obat obatan. PT Dexa berdiri pada Tahun 1969 di Palembang. Seiring berjalannya waktu PT Dexa kini berkembang menjadi perusahan yang semakin besar, dan mendirikan AAM (Anugrah Argon Medica) untuk mendistribusikan produk dexa medica. Untuk perusahaan yang cukup besar, maka PT Dexa sudah seharusnya menggunakan sistem komunikasi yang baik, untuk kelancaran aktivitas, sistem komunikasi yang di gunakan adalah telepon kabel. Namun penggunaan telepon kabel ini terdapat suatu masalah, yaitu terputusnya panggilan telepon pada saat d
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Machado, Eleuza R., Marlene T. Ueta, Rosângela Maria Rodrigues, et al. "Effects of dexamethasone, cyclosporine and betamethasone on inflammatory cell recruitment in mice infected with Strongyloides venezuelensis." Journal of Lung, Pulmonary & Respiratory Research 6, no. 4 (2019): 108–14. http://dx.doi.org/10.15406/jlprr.2019.06.00219.

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The objective of this study was verified effect of immunosuppressant activities of Dexametasone (Dexa), Cyclosporine (CsA) and Betamethasone (Beta) in the synhteses of inflammatory cell and dissemination of Strongyloides venezuelensis. S. venezuelensis- infected mice increased total leucocytes (TL), eosinophil (EO), mononuclear cells (MC), and neutrophil (NE) numbers in the blood. The infection induced recruitment of TL, EO and MC to peritoneal cavity (PCF) and space bronchoalveolar (BALF), exception for NE. Dexa, CsA and Beta treatments inhibited TL, EO and MC production. However, Dexa treatm
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Simranjit, Singh, K. Amandeep R, and Ray MM. "Assessment of Osteoporotic Fractures of Distal End of the Radius in Post-Menopausal Women by Using Dexa Scan." International Journal of Pharmaceutical and Clinical Research 14, no. 7 (2022): 31–36. https://doi.org/10.5281/zenodo.13367005.

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<strong>Background:</strong>&nbsp;Fractures of the distal radius are extremely common. The present study was conducted to evaluate osteoporotic fractures distal end of the radius in post-menopausal women by using dexa scan.&nbsp;<strong>Materials &amp; Methods:&nbsp;</strong>All the patients between 45 to75 year age group postmenopausal women of attending Orthopaedics department with fracture distal end of radius were included. All the patients would undergo height and weight measurement, noted about status of last menstrual period, amount of physical activity, activities causing joint pain. T
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Sheptulina, Anna F., Ekaterina O. Lyusina, Elvira M. Mamutova, Adel A. Yafarova, Anton R. Kiselev, and Oxana M. Drapkina. "Bioelectrical Impedance Analysis Demonstrates Reliable Agreement with Dual-Energy X-ray Absorptiometry in Identifying Reduced Skeletal Muscle Mass in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease and Hypertension." Diagnostics 14, no. 20 (2024): 2301. http://dx.doi.org/10.3390/diagnostics14202301.

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Background/Objectives: Body composition (BC) affects the risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD) and hypertension (HTN). Currently, dual-energy X-ray absorptiometry (DEXA) is considered the gold standard for assessing BC, even though it has some limitations, including immobility, ionizing radiation, and patient weight restrictions. The aim of the study was to evaluate the correlations of BC parameters measured by bioelectrical impedance analysis (BIA) with those measured by DEXA in patients with MASLD and HTN. Methods: Overall, 78 patients with MASLD
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Son, Hyran R., D. André d'Avignon, and Dorothy P. Laflamme. "Comparison of dual-energy x-ray absorptiometry and measurement of total body water content by deuterium oxide dilution for estimating body composition in dogs." American Journal of Veterinary Research 59, no. 5 (1998): 529–32. http://dx.doi.org/10.2460/ajvr.1998.59.5.529.

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Abstract Objective To compare percentage of body fat (%BF) estimates from dual-energy x-ray absorptiometry (DEXA) with those derived from total body water (TBW) determination by deuterium oxide (D2O) dilution. Animals 31 healthy, adult, purebred dogs of various ages and breeds (body weight, 15 to 39 kg). Procedure The TBW was measured by D2O dilution and subsequent analysis via nuclear magnetic resonance (NMR). Blood was collected before and 2 hours after IV administration of 275 mg of D2O/kg of body weight. Plasma was separated and stored at −30 C until analysis by deuterium NMR. The DEXA sca
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Alrawashdh, Neda, Abdulaali Almutairi, Ali McBride, and Ivo Abraham. "Economic Evaluation of Daratumumab and Pomalidomide and Dexamethasone Versus Isatuximab and Pomalidomide and Dexamethasone for Patients with Relapsed or Refractory Multiple Myeloma." Blood 136, Supplement 1 (2020): 19–20. http://dx.doi.org/10.1182/blood-2020-136348.

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Background. Although several new treatments are available for patients with multiple myeloma (MM), most patients eventually relapse at a median time of 8.0 months (95%CI: 6.3-8.9). Patients with relapsed and refractory MM (R/R MM) who have had several lines of previous therapy or who are refractory to lenalidomide and proteasome inhibitors require alternative options. Daratumumab and isatuximab are monoclonal antibodies that bind to the human CD38 receptor. Phase II/III clinical trials showed that isatuximab (ISA) or daratumumab (DARA) in combination with pomalidomide (POM-d) and low-dose dexa
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Kim, Kyung Joon, Dong Hwan Kim, Jae Il Lee, Byung Kwan Choi, In Ho Han, and Kyoung Hyup Nam. "Hounsfield Units on Lumbar Computed Tomography for Predicting Regional Bone Mineral Density." Open Medicine 14, no. 1 (2019): 545–51. http://dx.doi.org/10.1515/med-2019-0061.

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AbstractObjectiveBone mineral density (BMD) is a very important factor in spinal fusion surgery using instrumentation. Our aim was to investigate the utility of Hounsfield units (HU) obtained from preoperative lumbar computed tomography (CT) to predict osteoporosis coupling with data of quantitative computed tomography (QCT) and dual X-ray absorptiometry (DEXA).MethodsWe reviewed 180 patients that underwent both QCT and lumbar CT for spine surgery. HU was retrospectively calculated on the lumbar CT of 503 lumbar vertebrae from L1 to L3. Femur DEXA was performed in all patients and spine DEXA w
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Korewo-Labelle, Daria, Mateusz Jakub Karnia, Dorota Myślińska, and Jan Jacek Kaczor. "Supplementation with Vitamin D3 Protects against Mitochondrial Dysfunction and Loss of BDNF-Mediated Akt Activity in the Hippocampus during Long-Term Dexamethasone Treatment in Rats." International Journal of Molecular Sciences 24, no. 18 (2023): 13941. http://dx.doi.org/10.3390/ijms241813941.

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Dexamethasone (DEXA) is a commonly used steroid drug with immunosuppressive and analgesic properties. Unfortunately, long-term exposure to DEXA severely impairs brain function. This study aimed to investigate the effects of vitamin D3 supplementation during chronic DEXA treatment on neurogenesis, mitochondrial energy metabolism, protein levels involved in the BDNF-mediated Akt activity, and specific receptors in the hippocampus. We found reduced serum concentrations of 25-hydroxyvitamin D3 (25(OH)D3), downregulated proBDNF and pAkt, dysregulated glucocorticosteroid and mineralocorticoid recept
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Vicovan, Andrei Gheorghe, Diana Cezarina Petrescu, Aurelia Cretu, et al. "Targeting Common Inflammatory Mediators in Experimental Severe Asthma and Acute Lung Injury." Pharmaceuticals 17, no. 3 (2024): 338. http://dx.doi.org/10.3390/ph17030338.

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Neutrophils, known to be mobilized and activated in high amounts through Il-17 stimulation, are a key factor for clinical manifestation and imbalance of redox systems favoring a dominant oxidative state in both severe asthma and acute lung injury (f). The aim of this study was to evaluate in mice, the effect of Secukinumab (SECU) in a model of ovalbumin-induced asthma exacerbated with LPS administration to induce ALI, compared to dexamethasone (DEXA), already known for its benefit in both asthma and ALI. Results on cytokine levels for specific Th1, Th2 and Th17 revealed an interplay of immune
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Candra, Lissiani, Arief Iskandar, Indrastuti Normahayu, Putra Suryana, and Nanik Setijowati. "Akurasi Indeks Singh Dibandingkan Dual Energy X-Ray Absorptiometry (DEXA) dalam Evaluasi Osteoporosis." Jurnal Radiologi Indonesia 1, no. 1 (2015): 1–9. http://dx.doi.org/10.33748/jradidn.v1i1.1.

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Background: Osteoporosis is a metabolic bone disease that commonly occurs, characterized by decreased bone mass and prone to fracture. Breast carcinoma patients have a higher risk developing osteoporosis, due to a decrease in estrogen levels resulting from the e?ect of a given treatment, thus early detection of osteoporosis is needed.Objective: To compare the accuracy of the Singh Index with DEXA as the gold standard in the evaluation of osteoporosis in breast carcinoma patients with positive estrogen receptor.Materials and method: This is a diagnostic test, comparing the accuracy of the Singh
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Alibhai, S. M., M. Duong-Hua, R. Sutradhar, et al. "Bone health practices in men on androgen deprivation therapy (ADT): A population-based analysis of 25,802 patients." Journal of Clinical Oncology 27, no. 15_suppl (2009): 9631. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.9631.

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9631 Background: ADT is used in up to 1 in 2 men with prostate cancer. Osteoporosis and fragility fractures are important side effects of ADT. Guidelines recommend 2 important bone health practices for men on ADT - measurement of bone mineral density with dual x-ray absorptiometry (DEXA) and use of bisphosphonates in men at risk of osteoporosis. The implementation of these guidelines in practice is not well known. Methods: Using linked administrative databases, we identified 25,802 men (mean age 75.9 y, range 66–100 y) with prostate cancer who were treated with at least 6 months of ADT or who
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Mawby, Dianne I., Joseph W. Bartges, Andre d’Avignon, Dorothy P. Laflamme, Tamberlyn D. Moyers, and Tamorah Cottrell. "Comparison of Various Methods for Estimating Body Fat in Dogs." Journal of the American Animal Hospital Association 40, no. 2 (2004): 109–14. http://dx.doi.org/10.5326/0400109.

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Obesity is considered one of the most common forms of malnutrition occurring in dogs. Laboratory methods of evaluation of body composition in live dogs have included dual-energy X-ray absorptiometry (DEXA) and deuterium oxide (D2O) dilution. Clinical methods of evaluation include assigning a body condition score (BCS) based on visual observation, palpation, and morphometric measurements. This study used these four methods to evaluate 23 healthy, adult, client-owned dogs. Good correlation (coefficient of determination [r2]=0.78) was found between measurements of percent body fat (%BF) determine
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Labar, Boris, Stefan Suciu, Petra Muus, et al. "Dexamethasone Versus Methyl-Prednisolone in Induction Therapy for Adult Acute Lymphoblastic (ALL) and Non-Hodgkin Lymphoma (NHL) Patients ≤ 60 Yrs Old: Final Results of the Eortc All-4 Phase III Trial." Blood 106, no. 11 (2005): 1834. http://dx.doi.org/10.1182/blood.v106.11.1834.1834.

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Abstract In some recent trials high dose of Dexamethasone (Dexa) combined with chemotherapy has been used for induction therapy in adults with ALL because it may exert higher antileukemic activity. Increased level of drug in the cerebrospinal fluid might also prevent meningeal leukemic infiltration. However, high dose of Dexa may be associated with an increased risk of sepsis and fungal infections. By using a lower dose of dexamethasone these serious infections may be circumvented without jeopardize the antileukemic activity. The main aim of the EORTC ALL-4 study was to determine the efficacy
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46

Kim, Tae Nyun. "Use of Dual-Energy X-ray Absorptiometry for Body Composition in Chronic Disease Management." Journal of Korean Diabetes 23, no. 2 (2022): 97–105. http://dx.doi.org/10.4093/jkd.2022.23.2.97.

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Aging and chronic disease are often accompanied by changes in body composition that lead to decreased muscle mass and increased fat mass, even in weight-stable individuals. Both obesity and sarcopenia are important causes of frailty, disability, morbidity, and mortality. Diminished skeletal muscle and expanded visceral fat can act synergistically, which might maximize their effects on physical impairments and metabolic disorders. Dual-energy X-ray absorptiometry (DEXA) was regarded as one of the most versatile imaging techniques for evaluation of sarcopenia and obesity as well as osteoporosis.
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Hansen, N. J., T. G. Lohman, S. B. Going, et al. "Prediction of body composition in premenopausal females from dual-energy X-ray absorptiometry." Journal of Applied Physiology 75, no. 4 (1993): 1637–41. http://dx.doi.org/10.1152/jappl.1993.75.4.1637.

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Four methods for predicting body composition were compared in premenopausal females (n = 100), 28#x2013;39 yr old, by using underwater weighing (UWW) as the criterion method. The four methods were dual energy X-ray absorptiometry (DEXA), skinfolds, bioelectrical impedance, and body mass index. The sample had a mean percent fat (%fat) of 29.7 +/- 6.8% (SD) by DEXA and 29.9 +/- 5.8% measured by UWW. DEXA yielded a standard error of estimate (SE) of 2.4% (r = 0.91) for the prediction of %fat from UWW. When %fat was estimated from other methods, larger SEs were obtained: 3.0% for skin-folds, 3.3%
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Salamone, Loran M., Thomas Fuerst, Marjolein Visser, et al. "Measurement of fat mass using DEXA: a validation study in elderly adults." Journal of Applied Physiology 89, no. 1 (2000): 345–52. http://dx.doi.org/10.1152/jappl.2000.89.1.345.

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The accuracy of total body fat mass and leg fat mass measurements by fan-beam dual-energy X-ray absorptiometry (DEXA) was assessed in 60 healthy elderly subjects (aged 70–79 yr). Total fat and leg fat mass at four leg regions (total leg, thigh, midthigh, and calf) were measured with the QDR 4500A (Hologic, Waltham, MA). The four-compartment model and multislice computed tomography scans were selected as criterion methods for total fat and leg fat mass, respectively. Total fat mass from DEXA was positively associated with fat mass from the four-compartment model with a standard error of the est
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Pineau, Jean-Claude, Jean Robert Filliard, and Michel Bocquet. "Ultrasound Techniques Applied to Body Fat Measurement in Male and Female Athletes." Journal of Athletic Training 44, no. 2 (2009): 142–47. http://dx.doi.org/10.4085/1062-6050-44.2.142.

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Abstract Context: For athletes in disciplines with weight categories, it is important to assess body composition and weight fluctuations. Objective: To evaluate the accuracy of measuring body fat percentage with a portable ultrasound device possessing high accuracy and reliability versus fan-beam, dual-energy X-ray absorptiometry (DEXA). Design: Cross-validation study. Setting: Research laboratory. Patients or Other Participants: A total of 93 athletes (24 women, 69 men), aged 23.5 ± 3.7 years, with body mass index = 24.0 ± 4.2 and body fat percentage via DEXA = 9.41 ± 8.1 participated. All pa
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Hayasaka, Naomi, Tsuyoshi Yaita, Tomoyuki Kuwaki, et al. "Optimization of Dosing Schedule of Daily Inhalant Dexamethasone to Minimize Phase Shifting of Clock Gene Expression Rhythm in the Lungs of the Asthma Mouse Model." Endocrinology 148, no. 7 (2007): 3316–26. http://dx.doi.org/10.1210/en.2007-0010.

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Glucocorticoid receptor agonists such as dexamethasone (DEXA) have been recommended for the treatment of asthma. An increased frequency of dosing with these drugs seems preferable for cases of severe or uncontrolled asthma. The purpose of this experiment was to find the appropriate dosing schedule (frequency and timing) for DEXA inhalation based on chronotherapeutic dosing to minimize phase shifts of clock function in the lungs of the ovalbumin-treated asthmatic mouse. The daily rhythm of clock gene expression was similar between control and ovalbumin-treated mice. Acute inhalation of DEXA sig
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