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1

Dijk-Wolthuis, Welmoed van. "Biodegradable dextran hydrogels for pharmaceutical applications = Bioafbreekbare dextraan-hydrogelen voor farmaceutische toepassingen /." [S.l. : s.n.], 1997. http://www.gbv.de/dms/bs/toc/238021521.pdf.

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Piazza, Rodolfo Debone [UNESP]. "Modificação da superfície de óxidos de ferro por dextrana derivatizada para aplicações em liberação de fármaco." Universidade Estadual Paulista (UNESP), 2014. http://hdl.handle.net/11449/110705.

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Piazza, Rodolfo Debone. "Modificação da superfície de óxidos de ferro por dextrana derivatizada para aplicações em liberação de fármaco /." Araraquara, 2014. http://hdl.handle.net/11449/139300.

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Orientador: Miguel Jafelicci Junior<br>Banca: Marcio José Tiera<br>Banca: Carolina Vautier Teixeira Giongo<br>Resumo: A modificação da superfície de nanopartículas de óxido de ferro tem atraído interesse da comunidade científica devido às várias aplicações deste material em diferentes áreas do conhecimento. A biomedicina é uma área em crescente avanço no uso das nanopartículas, pois a sinergia entre as propriedades magnéticas e a biocompatibilidade da superfície modificada permite o uso destes materiais em diagnóstico e tratamento de doenças, como na liberação controlada de drogas. A aplicação
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Faivre, Béatrice. "Un transporteur d'oxygène a visée transfusionnelle : l'hémoglobine-dextran 10-benzène-tetracarboxylate évaluation préclinique chez le cobaye." Vandoeuvre-les-Nancy, INPL, 1993. http://www.theses.fr/1993INPL086N.

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L'hémoglobine conjuguée au dextran-benzène-tetracarboxylate (hb-dex-btc) est un transporteur d'O2 dont les objectifs sont de se substituer, de façon temporaire, à la fonction oxyphorique des hématies et de contribuer à la restauration de la volémie. Notre travail consiste à réaliser l'évaluation pharmaco-toxicologique de cette hémoglobine. Tout d'abord, nous présentons l'historique de la recherche sur les substituts du sang, la physiologie de l'hémoglobine dans le globule rouge et dans le plasma (structure, mécanismes d'oxygénation, d'oxydation, de réduction, catabolisme) ainsi que les princip
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5

Landon, Robert Stephen. "Optimisation of the dextran fermentation." Thesis, University of Manchester, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333270.

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Delattre, Cécilia. "Mise au point et évaluation de nouveaux revêtements de stents pour application cardio-vasculaire." Thesis, Sorbonne Paris Cité, 2015. http://www.theses.fr/2015USPCD061/document.

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L’objectif de ce travail est d’évaluer la biocompatibilité d’un copolymère de Dextrane- Polybutylmethacrylate utilisé comme revêtement de stent métallique en Cobalt-Chrome. L’étude s’est déroulée en trois phase : 1/La production du polymère et la caractérisation physico-chimique, 2/L’évaluation in vitro et 3/L’évaluation in vivo dans plusieurs modèles. Dans un premier temps deux copolymères de concentrations distinctes ont été synthétisés et mis en forme pour les différentes expériences. Leur caractérisation par FTIR, mesure d’angle de contact et une première implantation in vivo évaluant la r
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Bhambra, Kalwant S. "The fractionation of dextran using ethanol." Thesis, Aston University, 1985. http://publications.aston.ac.uk/10231/.

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8

Faucher-Sivera, Nadine. "Contribution à l'étude d'un nouveau dextran de poids moléculaire 40 000 (plasmacair R) : pharmacocinétique et effets rhéologiques." Montpellier 1, 1988. http://www.theses.fr/1988MON11068.

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9

Claverie, Marion. "GH70 dextransucases : Insights on the molecular determinants of dextran molar mass control." Thesis, Toulouse, INSA, 2017. http://www.theses.fr/2017ISAT0037/document.

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Les glucane-saccharases (GS) de la famille GH70 sont des enzymes produites par certaines bactéries lactiques. A partir de saccharose, substrat renouvelable et peu coûteux, elles sont capables de catalyser la synthèse d’α-glucanes, homopolysaccharides dont les propriétés diffèrent suivant la spécificité de l’enzyme (taille, type de liaisons α-osidiques, degrés de branchement). Les glucanes contenant une très grande majorité de liaisons α-(1,6), appelés dextranes, présentent de nombreuses applications industrielles qui dépendent principalement de leur taille. Cependant, la synthèse directe de de
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10

Crepon, Bertrand. "Dérivés du dextrane : substituts de plasma sanguin." Paris 13, 1988. http://www.theses.fr/1988PA132001.

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11

Frank, Laetitia Monchecourt. "Etude des propriétés cicatrisantes de dextranes fonctionnalisés." Paris 13, 2003. http://www.theses.fr/2003PA132013.

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La cicatrisation est un mécanisme complexe pouvant aboutir, lors de dérégulations, à la formation de plaies chroniques et hypertrophiques. Dans le but d'améliorer la cicatrisation, les facteurs de croissances impliqués dans ce mécanisme ont été étudiés. Dans ce contexte un dérivé du dextrane, substitué par des groupements carboxyméthylates, benzylamides et sulfates, a été sélectionné pour son effet sur la prolifération des fibroblastes dermiques humains. Deux domaines d'étude ont été réalisés selon que les fibroblastes dermiques humains sont cultivées en monocouche ou inclus dans un réseau de
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12

Fasan, Gilles. "Etude de l'hémoglobine issue du fractionnement de sang placentaire et application à la production d'hémoglobine fonctionnelle : optimisation de la préparation d'un conjugué hémoglobine-dextrane utilisable comme substitut sanguin." Vandoeuvre-les-Nancy, INPL, 1990. http://www.theses.fr/1990INPL075N.

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Ce travail de thèse a consisté à mettre en évidence la nature et la cause de l'altération fonctionnelle de l'hémoglobine isolée à partir de sang placentaire, grâce à une étude structurale. Cette altération est due à une arginine carboxypeptidase présente dans le placenta qui hydrolyse l'Arg 141 alpha c-terminale de l'HB, provoquant une augmentation de son affinité pour l'O2 et la perte de sa coopérativité. Nous avons également mis au point une méthode de réduction de la méthémoglobine par l'ascorbate de sodium, utilisable sur plusieurs litres de solution d'hémoglobine. Ces résultats nous ont p
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Sarbini, Shahrul Razid. "Investigation of dextran oligosaccharides as a potential prebiotic." Thesis, University of Reading, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.559367.

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In this study, a range of novel and commercially available dextran-based gluco- oligosaccharides with different structures (percentage of a-l,2 linkages) and molecular weights were investigated to establish a link between structure and function of candidate colonic prebiotics. Their fermentation properties were tested in pH-controlled faecal batch cultures and the response of the healthy microbiota was monitored through fluorescent in situ hybridization, enumerating numerically and clinically significant bacterial groups and their metabolic activities through the determination of short chain f
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Rabut, François. "La streptodecase : streptokinase - dextran : effets cliniques et biologiques." Bordeaux 2, 1988. http://www.theses.fr/1988BOR25200.

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15

Till, Andrew. "The production of clinical dextran using membrane processes." Thesis, Aston University, 1988. http://publications.aston.ac.uk/9728/.

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Clinical dextran is used as a blood volume expander. The British Pharmacopeia (BP) specification for this product requires the amount of dextran below 12,000 MW and above 98,000 MW to be strictly controlled. Dextran is presently fractionated industrially using ethanol precipitation. The aim of this work was to develop an ultrafiltration system which could replace the present industrial process. Initially these molecular weight (MW) bands were removed using batch ultrafiltration. A large number of membranes were tested. The correct BP specification could be achieved using these membranes but th
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16

Zhang, Rongsheng. "Dextran hydrogel preparation and applications in biomedical engineering." Thesis, University of Bath, 2004. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398371.

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Jesus, Chelry Fernanda Alves de. "Síntese e caracterização de nanopartículas de maghemita associada à dextrana funcionalizada com rodamina B." Universidade Federal de Goiás, 2014. http://repositorio.bc.ufg.br/tede/handle/tede/3065.

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Alves, Fernanda Viginotti. "Interferência do amido e da dextrana nas análises tecnológicas do caldo de cana-de-açúcar." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/11/11141/tde-20052013-163950/.

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A indústria Sucroenergética tem como uma de suas preocupações atuais a presença de polissacarídeos, como o amido e a dextrana, no caldo de cana-deaçúcar. Além de afetar a qualidade do açúcar, estes polissacarídeos podem alterar resultados de análises tecnológicas do caldo e, possivelmente, causar erros no pagamento da cana. Foram objetivos deste estudo: a) isolar e caracterizar o amido isolado de cana da variedade RB 86-7515 e b) avaliar a interferência de adições crescentes deste amido isolado e de dextranas comerciais com pesos moleculares 40.000 e 5.348.000 Dalton nas análises de polarimetr
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Ibegbu, Madu Daniel. "Functionalised dextran nanoparticles for drug delivery to the brain." Thesis, University of Portsmouth, 2015. https://researchportal.port.ac.uk/portal/en/theses/functionalised-dextran-nanoparticles-for-drug-delivery-to-the-brain(c2da4093-315e-4647-90e1-4340acf2b8bd).html.

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Towards the development of drug carriers that are capable of crossing the Blood Brain Barrier, the techniques of emulsion polymerisation and nanoprecipitation have been utilised to produce nanoparticulate carriers from a systematic series of alkylglyceryl dextrans (of two different average molecular weights, 6 kDa and 100 kDa) that had been functionalised with ethyl and butyl cyanoacrylates. Also, zero length grafting of polylactic acid to butyl, octyl and hexadecylglyceryl dextrans has allowed the preparation of polylactic acid-functionalised nanoparticles. All materials and derived nanoparti
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Duverger, Daniel. "Choc anaphylactique aux solutes de remplissage : dextran et gelatine." Lille 2, 1991. http://www.theses.fr/1991LIL2M174.

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Aldujaili, Aya, Emma Berndtson, Tom Hedström, Sofia Piccolo, Zakaria Rahmani, and Michelle Åhlén. "Hur partikelstorleksfördelning påverkar kritiska parametrar för medicinska enheter." Thesis, Uppsala universitet, Institutionen för teknikvetenskaper, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-255914.

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Projektet har inriktning på Galdermas produkter Deflux och Solesta, de ämnen som produkterna är uppbyggda av (dextran och hyaluronsyra) har studerats laborativt. Ändringar av parametrar såsom koncentration av dextran men även i siktningsmetod (dubbel- respektive enkelsiktningar samt olika filterstorlekar) har genomförts. Resultatet av dessa ändringar har erhållits med hjälp av mikroskop, laserdiffraktometer samt dragprovare. De slutsatser som har kunnat dras från resultaten är att med ökad partikeldiameter erhålls en lägre extruderingskraft, oavsett om använd siktningsmetod var enkel- eller du
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Tournon-Aubry, Isabelle Aubry. "Intérêt de l'hémodilution normovolémique par dextrans dans le traitement des occlusions veineuses rétiniennes (étude sur 38 cas)." Montpellier 1, 1988. http://www.theses.fr/1988MON11202.

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Machy, Delphine. "Développement de nouvelles prothèses enduites de dextrane et de dérivé de dextrane." Paris 13, 2002. http://www.theses.fr/2002PA132023.

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L'enduction des prothèses vasculaires est un pré-requis pour éviter les risques hémorragiques à travers la prothèse. Actuellement les prothèses vasculaires sont principalement enduites par du colagène réticulé. Cependant ce revêtement est très coûteux et présente le risque de véhiculer des agents pathogènes. Dans ce contexte nous avons développé un nouveau revêtement pour prothèse vasculaire en polyéthylène térephtalate à base de dextrane<br>It is essential that a synthetic vascular graft in polyethylene terephalate is preclotting prior to implantation in order to prevent blood leakig through
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Engrand, Philippe Regnouf de Vains Jean-Bernard. "Calix[4]arènes fonctionnels pour ancrage sur polymère naturel et antennisation par le tripeptide RGD préparé par synthèse convergente." S. l. : Nancy 1, 2008. http://www.scd.uhp-nancy.fr/docnum/SCD_T_2008_0143_ENGRAND.pdf.

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Galvosas, Petrik, Ying Qiao, Thorsteinn Adalsteinsson, Monika Schönhoff, and Paul T. Callaghan. "Diffusion exchange NMR spectroscopic study of dextran exchange through polyelectrolyte multilayer capsules: Diffusion exchange NMR spectroscopic study of dextran exchangethrough polyelectrolyte multilayer capsules." Diffusion fundamentals 3 (2005) 30, S. 1-2, 2005. https://ul.qucosa.de/id/qucosa%3A14321.

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Núñez, Eutimio Gustavo Fernández. "Desenvolvimento de conjugados de dextran manose radiomarcados para detecção de linfonodo sentinela." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/85/85131/tde-29062011-164358/.

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O diagnóstico precoce de tumores e metástase constitui atualmente o elemento de maior impacto dentro das políticas de saúde públicas contra o câncer. No câncer de mama e melanoma, a técnica de biópsia de linfonodo sentinela, para o diagnostico de metástase, tem sido muito utilizada evitando a dissecção total dos nodos da região anatômica afetada, e permitindo definir com precisão o procedimento terapêutico a utilizar. O objetivo principal deste trabalho centrou-se no desenvolvimento de conjugados radiomarcados de dextran-manose para diagnóstico, utilizando o núcleo de tecnécio altamente estáve
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Breitenbach, Bernhard Benjamin [Verfasser]. "Responsive Polysaccharide Macrosurfactants from Dextran Building Blocks / Bernhard Benjamin Breitenbach." Mainz : Universitätsbibliothek Mainz, 2020. http://d-nb.info/1203081278/34.

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Xu, Ying Hua. "Role of cytokines in murine dextran sulphate sodium-induced colitis." Thesis, The University of Sydney, 2008. https://hdl.handle.net/2123/28171.

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Idiopathic inflammatory bowel diseases (IBD), usually referred to as ulcerative colitis (UC) and Crohn’s disease (CD), are chronic inflammatory disorders of the gastrointestinal tract, characterized by periods of remission and relapse. It is a significant public health problem in developed countries, affecting 1 in 1,000 individuals. Despite years of intensive research, the aetiology and pathogenesis of IBD remain unclear. The most prevalent working hypothesis is that IBD results from the complex interaction of genetic, immunological and environmental factors.
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Liu, Xiaochen. "Preparation and functional investigation of proteaseinhibitors conjugated to soluble dextran." Thesis, Uppsala universitet, Institutionen för kemi - BMC, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-364712.

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Manarim, Gislene Roberta. "Interferentes analíticos provenientes da colheita, carregamento e transporte nas análises tecnológicas de caldo de cana-de-açúcar." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/11/11138/tde-26072017-104032/.

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As técnicas analíticas empregadas na determinação da qualidade da canade- açúcar são muito importantes para a indústria de processamento dessa matériaprima, uma vez que é a maneira mais eficiente de determinar a quantidade de sacarose, glicose, frutose e fibras que entra no processo. Aos fornecedores de cana-de-açúcar, é o momento da remuneração pela quantidade e qualidade de cana-de-açúcar que entrega ao processo. O Conselho dos Produtores de Cana-deaçúcar, Açúcar e Álcool do Estado de São Paulo - CONSECANA, determina a metodologia analítica de qualidade dessa matéria-prima e os cálculos para
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Rangel, Euzcateguy Geraldine del Valle. "Synthèse, formulation et caractérisation d’organogels aqueux moléculaires/macromoléculaires à base de produits bio-sourcés." Electronic Thesis or Diss., Université de Lorraine, 2020. http://www.theses.fr/2020LORR0300.

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Dans ce travail, un acide aminé naturel, la lysine, a été modifié chimiquement pour synthétiser trois agents gélifiants de structures similaires et différant les uns des autres par un ou deux groupes fonctionnels. Les trois molécules étaient entièrement solubles dans le diméthylsulfoxyde (DMSO) et les mélanges gélifiés DMSO/H2O avec diverses compositions donnant naissance à des organogels aqueux. Des hydrogels pourraient être produits après dialyse de gels DMSO/H2O. La résistance mécanique des gels, la réversibilité thermique/mécanique, la température de transition gel-sol ainsi que la cinétiq
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Filzen, Lars. "Einfluss von moderater Hämodilution mit Dextran-Konjugiertem Hämoglobin auf die Mikrozirkulation." Diss., lmu, 2007. http://nbn-resolving.de/urn:nbn:de:bvb:19-66085.

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Beck, Stephanie Christine. "Phase separation phenomena in cellulose nanocrystal suspensions containing dextran-dye derivatives." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=102956.

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Sulfuric acid hydrolysis of native cellulose fibers produces stable suspensions of cellulose nanocrystals. Within a specific concentration range, the suspensions spontaneously form an anisotropic chiral nematic liquid crystal phase. This thesis examines the phase separation behaviour of these suspensions, alone and in the presence of added macromolecules. Initially, the effect of hydrolysis conditions on the nanocrystal and phase separation properties for hydrolyzed softwood pulp were investigated and compared to suspensions prepared from hardwood pulp. The macromolecules studied, blue dextran
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Shakhov, Alexander, Jörg Kärger, and Rustem Valiullin. "Tracing molecular propagation in dextran solution by pulsed field gradient NMR." Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-183620.

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Shakhov, Alexander, Jörg Kärger, and Rustem Valiullin. "Tracing molecular propagation in dextran solution by pulsed field gradient NMR." Diffusion fundamentals 20 (2013) 74, S. 1-2, 2013. https://ul.qucosa.de/id/qucosa%3A13663.

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Yuan, Shengmei. "Preparation of nonthrombogenic polymer surfaces: Immobilization of heparin and dextran oligosaccharides." Case Western Reserve University School of Graduate Studies / OhioLINK, 1994. http://rave.ohiolink.edu/etdc/view?acc_num=case1061486885.

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Poland, Keith R. "The fractionation of dextran polymer by ultrafiltration to yield clinical products." Thesis, Aston University, 1986. http://publications.aston.ac.uk/10223/.

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A review of ultrafiltration (UF) theory and equipment has been made. Dextran is fractionated industrially by ethanol precipitation, which is a high energy intensive process. The aims of this work were to investigate the fractionation of dextran using UF and to compare the efficiency and costs of UF fractionation with ethanol fractionation. This work is the continuation of research conducted at Aston, which was concerned with the fractionation of dextran using gel permeation chromatography (GPC) and hollow fibre UF membranes supplied by Amicon Ltd. Initial laboratory work centred on determining
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Zafar, Imran A. "Biosynthesis and separation of dextran fructose mixtures in a chromatographic reactor." Thesis, Aston University, 1986. http://publications.aston.ac.uk/10219/.

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A literature review of work carried out on batch and continuous chromatographic biochemical reactor-separators has been made. The major part of this work has involved the development of a batch chromatographic reactor-separator for the production of dextran and fructose by the enzymatic action of the enzyme dextransucrase on sucrose. In this reactor, simultaneous reaction and separation occurs thus reducing downstream processing and isolation of products as compared to the existing industrial process. The chromatographic reactor consisted of a glass column packed with a stationary phase consis
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Oliveira, Roselaine Pinheiro de. "Ressuscitação hipertônica com salina/dextran em pacientes sépticos graves estáveis : um estudo randomizado." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2001. http://hdl.handle.net/10183/6289.

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Objetivo: estudar os efeitos hemodinâmicos da solução salina hipertônica/dextran, comparada com solução salina normal, em pacientes com sepse grave. Modelo: ensaio clínico randomizado, prospectivo, duplo-cego, controlado. Local: Unidade de Terapia Intensiva de um hospital universitário. Pacientes: 29 pacientes com sepse grave, admitidos na UTI com pressão de oclusão da artéria pulmonar (POAP) menor que 12 mmHg. Intervenções: os pacientes foram randomizados para receber 250 ml da solução salina normal [NaCl 0,9%] (Grupo SS, n=16) ou solução salina hipertônica [NaCl 7,5%]/dextran 70 8% ( Grupo S
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Liu, Shwu-Huey. "Part I. Photoaffinity labeling of chymotrypsin with polyfluorinated aryl azides ; Part II. The determination of dextran average chain length and bonding specificity during dextransucrase catalyzed formation of dextran /." The Ohio State University, 1990. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487685204968245.

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Frazier, Richard Andrew. "Macromolecular interactions at polysaccharide surfaces." Thesis, University of Nottingham, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.336946.

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Engrand, Philippe. "Calix[4]arènes fonctionnels pour ancrage sur polymère naturel et antennisation par le tripeptide RGD préparé par synthèse convergente." Thesis, Nancy 1, 2008. http://www.theses.fr/2008NAN10143/document.

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Ce travail porte sur la valorisation du calix[4]arène comme complexant de métaux de transition, immobilisé sur un matériau, et comme vecteur de principe actifs, aptes à interagir avec des récepteurs cellulaires. En premier lieu, la monofonctionnalisation sélective d’un calix[4]arène, sur sa partie haute ou sur sa partie basse est réalisée. Les fonctions nitro, amine, adéhyde, et alcène ont été incorporées sur la partie basse, via un bras espaceur, et un bras acide a été incorporé sur la partie haute. Ces calix[4]arènes monofonctionnalisés se déclinent en trois séries de composés, dépendant du
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Matthíasson, Stefán E. "Low molecular weight heparin and dextran in thromboprophylaxis human and experimental studies /." Malmö : Dept. of Surgery, Lund University, Malmö General Hospital, 1994. http://books.google.com/books?id=9OxsAAAAMAAJ.

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Kind, Clive Nicholas. "Biochemical aspects of the fate of imferon (iron-dextran) in the body." Thesis, De Montfort University, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.280510.

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Galvosas, Petrik, Ying Qiao, Thorsteinn Adalsteinsson, Monika Schönhoff, and Paul T. Callaghan. "Diffusion exchange NMR spectroscopic study of dextran exchange through polyelectrolyte multilayer capsules." Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-194947.

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Galvosas, Petrik, Ying Qiao, Paul T. Callaghan, Thorsteinn Adalsteinsson, and Monika Schönhoff. "Diffusion exchange NMR spectroscopic study of dextran exchange through polyelectrolyte multilayer capsules." Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-196873.

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FERNANDEZ, NUNEZ EUTIMIO G. "Desenvolvimento de conjugados de dextran manose radiomarcados para deteccao de linfonodo sentinela." reponame:Repositório Institucional do IPEN, 2011. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9957.

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Abstract:
Made available in DSpace on 2014-10-09T12:33:13Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:06:12Z (GMT). No. of bitstreams: 0<br>Tese (Doutoramento)<br>IPEN/T<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP
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Galvosas, Petrik, Ying Qiao, Paul T. Callaghan, Thorsteinn Adalsteinsson, and Monika Schönhoff. "Diffusion exchange NMR spectroscopic study of dextran exchange through polyelectrolyte multilayer capsules." Diffusion fundamentals 2 (2005) 118, S. 1-2, 2005. https://ul.qucosa.de/id/qucosa%3A14459.

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Miao, Xiao Su. "Tetrandrine inhibits dextran sulfate sodium-induced mouse colitis by promoting M2 differentiation." Thesis, University of Macau, 2018. http://umaclib3.umac.mo/record=b3952152.

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Li, Siu-ming Ian. "A study of cyclophosphamide on dextran sulfate sodium-induced ulcerative colitis in mice." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B31971994.

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