Journal articles: 'DFMA'

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Annamalai, K., C. D. Naiju, S. Karthik, and M. Mohan Prashanth. "Early Cost Estimate of Product during Design Stage Using Design for Manufacturing and Assembly (DFMA) Principles." Advanced Materials Research 622-623 (December 2012): 540–44. http://dx.doi.org/10.4028/www.scientific.net/amr.622-623.540.

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Application of Design for Manufacturing (DFM) and Design for Assembly (DFA) methodologies can be beneficial to industries involved in the design and development of products. Improper design decisions are responsible for higher manufacturing cost for a product. Thus it is important to include DFMA by combining principles of both DFM and DFA principle early in the design process. This paper presents a case study of manufacture and assembly costs estimation during the design phase of washing machine and which is to be manufactured in company located in India, and intends to make this economically feasible. Solidworks and Solidview software tool were used to generate CAD models which were further analysed using DFMA software tool. The result obtained was accepted by industry and match with the market value of washing machine.

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Slocum, R. D., A. J. Bitonti, P. P. McCann, and R. P. Feirer. "dl-α-difluoromethyl[3,4-3H]arginine metabolism in tobacco and mammalian cells. Inhibition of ornithine decarboxylase activity after arginase-mediated hydrolysis of dl-α-difluoromethylarginine to dl-α-difluoromethylornithine." Biochemical Journal 255, no. 1 (October 1, 1988): 197–202. http://dx.doi.org/10.1042/bj2550197.

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DL-alpha-Difluoromethylarginine (DFMA) is an enzyme-activated irreversible inhibitor of arginine decarboxylase (ADC) in vitro. DFMA has also been shown to inhibit ADC activities in a variety of plants and bacteria in vivo. However, we questioned the specificity of this inhibitor for ADC in tobacco ovary tissues, since ornithine decarboxylase (ODC) activity was strongly inhibited as well. We now show that [3,4-3H]DFMA is metabolized to DL-alpha-difluoromethyl[3,4-3H]ornithine [(3,4-3H]DFMO), the analogous mechanism-based inhibitor of ODC, by tobacco tissues in vivo. Both tobacco and mammalian (mouse, bovine) arginases (EC 3.5.3.1) hydrolyse DFMA to DFMO in vitro, suggesting a role for this enzyme in mediating the indirect inhibition of ODC by DFMA in tobacco. These results suggest that DFMA may have other effects, in addition to the inhibition of ADC, in tissues containing high arginase activities. The recent development of potent agmatine-based ADC inhibitors should permit selective inhibition of ADC, rather than ODC, in such tissues, since agmatine is not a substrate for arginase.

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Wang, Shiow Y., and Miklos Faust. "Changes in Polyamine Content during Dormancy in Flower Buds of `Anna' Apple." Journal of the American Society for Horticultural Science 119, no. 1 (January 1994): 70–73. http://dx.doi.org/10.21273/jashs.119.1.70.

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Polyamine, putrescine, spermidine, and spermine contents were determined during endodormancy in the buds of low-chilling-requiring `Anna' apples (Malus domestics Borkh.). Putrescine, spermidine, and spermine contents increased greatly in buds when their chilling requirement was satisfied. Polyamine biosynthetic inhibitors α -difluoromethylarginine (DFMA) or α -difluoromethylornithine (DFMO) reduced bud break and bud growth in concert with decreased polyamine titers. DFMO or DFMA did not inhibit bud break when it was applied to buds after they received the full chilling requirement. DFMO was more inhibitory than DFMA. The polyamine requirement was much higher for bud growth and bud development than during differentiation and bud break.

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Harik, Ramy F., and Najwa Sahmrani. "DFMA+, A Quantitative DFMA Methodology." Computer-Aided Design and Applications 7, no. 5 (January 2010): 701–9. http://dx.doi.org/10.3722/cadaps.2010.701-709.

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Saniewska, Alicja. "Effect of polyamine biosynthesis inhibitors on in vitro growth of Phyllosticta antirrhini Sydow and on the infection of Antirrhinum majus L. by the pathogen." Acta Agrobotanica 52, no. 1-2 (2013): 11–18. http://dx.doi.org/10.5586/aa.1999.002.

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Polyamine biosynthesis inhibitors, DL-α-difluromethylornithine (DFMO) and DL-α-difluromethylarginine (DFMA) at concentrations of 1,0 and 3,0 mM greatly inhibited mycelial growth of <em>Phyllosticta antirrhini</em> on Czapek Dox Agar (CDA). Putrescine at the concentration of 1,0 mM completely reversed the inhibitory effect of DFMO but only partially that of DFMA. Both polyamine biosynthesis inhibitors at concentrations 1,0 and 3,0 mM applied preventively and curatively strongly inhibited the development of the pathogen on snapdragon leaves.

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Saftner, Robert A., William S. Conway, and Carl E. Sams. "Effects of Some Polyamine Biosynthesis Inhibitors and Calcium Chloride on In Vitro Growth and Decay Development in Apples Caused by Botrytis cinerea and Penicillium expansum." Journal of the American Society for Horticultural Science 122, no. 3 (May 1997): 380–85. http://dx.doi.org/10.21273/jashs.122.3.380.

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Three polyamine biosynthesis inhibitors, α-difluoromethylornithine (DFMO), α-difluoromethylarginine (DFMA), and α-methylornithine (MeOrn), alone and in combination with CaCl2, were tested for their ability to reduce in vitro growth and soft rot development in apple (Malus domestica Borkh.) fruit caused by Botrytis cinerea Pers.:Fr. and Penicillium expansum Link. All three inhibitors reduced the in vitro growth of the pathogens. Calcium had no effect on fungal growth in vitro. Pressure infiltration of millimolar concentrations of DFMO or DFMA or 25 g·L-1 CaCl2 solutions into apples reduced subsequent soft rot development by B. cinerea and P. expansum >40%. A combination treatment of Ca and DFMO or DFMA reduced decay >67%. Treatment of apples with MeOrn was less effective at inhibiting decay development. None of the inhibitors affected polyamine levels in apple cortical tissues. Some injury to the fruit surface was observed with Ca treatments. Fruit treated with Ca and any of the inhibitors were less firm than those treated with Ca alone. Specific polyamine biosynthesis inhibitors in combination with Ca may prove useful in reducing postharvest decay in apples.

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Rudiyantoro, Rudiyantoro, and Yunia Dwie Nurcahyanie. "Metodologi Eco Desain Yang Digunakan Untuk Pengembangan Produk Furniture Berbasis Logam Secara Berkelanjutan." WAKTU: Jurnal Teknik UNIPA 13, no. 1 (March 23, 2016): 19–29. http://dx.doi.org/10.36456/waktu.v13i1.23.

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Pengembangan produk harus memikirkan detail baik pemilihan material, proses produksi, proses perkitan, sampai pada bagaimana perawatan produk setelah diterima konsumen. Semua menjai satu proses panjang menuju keberlanjutan hidup produk. Pada prinsipnya semakin sederhana material, menggunakan finishing non toxic, sistem sambungan sederhana, menggunakan kemasan yang berbahan ramah lingkungan, ukuran kemasan diperkecil. Dengan proses yang disederhanakan, mesin produksi yang digunakan bisa lebih ditekan, artinya semakin sedikit mesin produksi yang digunakan, energi untuk menggerakkan mesin bisa lebih hemat. Semakin sedikit jumlah material yang digunakan semakin sedikit limbah paska umur hidup produk berakhir. Pemilihan bahan sangat berpengaruh pada proses daur ulang, guna ulang produk. Dengan metode desain yang memperhitungkan perakitan(DfA), manufaktur (DfM), perawatan (DfMaintanance) maka sebuah produk akan bertahan lebih lama umur hidupnya (Sustainable Product Development-SPD), proses produksi lebih disingkat, energi lebih hemat, kemasan bisa lebih ringkas. Kata Kunci : Desain, DfA,DfM,DfMa, SpD

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Guo, Ping, Xiao Zhao, and Zheng Gang Xiao. "Synthesis, Morphology and Hydrophobicity of Core-Shell Fluoinated Copolymer Latexes." Applied Mechanics and Materials 456 (October 2013): 471–73. http://dx.doi.org/10.4028/www.scientific.net/amm.456.471.

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The fluoroacrylate copolymer latexes (Poly (BA-MMA-DFMA) latex) with a fluorinated shell were successfully synthesized by semi-continuous seeded emulsion polymerization. The chemical structure of the latex was characterized by Fourier transform infrared (FTIR) and 1H-NMR analysis. Glass transition temperatures (Tg) of Poly (BA-MMA-DFMA) latex were confirmed by DSC analysis. Transmission electron microscopy (TEM) showed the microstructure of Poly (BA-MMA-DFMA) latex. The water absorption ratio and the water contact angle (WCA) of films were studied. Results showed the Poly (BA-MMA-DFMA) latex had two distinct Tg and exhibited core-shell structure. Moreover, Poly (BA-MMA-DFMA) film with 15wt% DFMA can exhibit lower water absorption ratio and higher contact angle.

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Parker, Miles. "Breathing easier with DFMA." World Class Design to Manufacture 2, no. 6 (December 1995): 17–20. http://dx.doi.org/10.1108/09642369310104255.

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Raplee, Jack. "DFMA to RP, ASAP." Mechanical Engineering 121, no. 09 (September 1, 1999): 72–74. http://dx.doi.org/10.1115/1.1999-sep-5.

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Manufacturing companies are turning increasingly to rapid prototyping (RP) to perform pre-assembly testing and improve the quality of the final product. Manufacturers also have begun to complement their RP practices using design for manufacture and assembly methodology. Design for assembly lowers the complexity of products through parts reduction and enables manufacturers to quantify assembly times and costs. Users are prompted to consider each part and decide if it must be separate from others in the assembly, leading to systematic simplification of design. The four approaches by which design for manufacturer (DFMA) software analyzes product configurations incorporate design for assembly, design for manufacture, design for service, and design for environment. Using design for assembly can reduce the number of parts in the product, but can increase the complexity of the parts that remain. Rapid prototyping combined with DFMA tools not only can determine if a product will perform its desired functions. According to an expert, when early manufacturing process planning is performed using DFMA and RP, it is synergistic.

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Silva, Carlos Eduardo Sanches da. "ASSESSING INTEGRATION OF COMPUTER SIMULATION IN DESIGN FOR MANUFACTURING AND ASSEMBLY." Brazilian Journal of Operations & Production Management 14, no. 1 (May 15, 2017): 48. http://dx.doi.org/10.14488/bjopm.2017.v14.n1.a6.

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The process of product development strengthens as a reason for competitiveness, using sundry optimisation methods, e.g. Design for Manufacturing and Assembly (DFMA). Simulating allows engineers or managers to obtain a systemic perspective of how local changes will affect the overall performance over the entire production system, obtaining thus its optimisation. In this study, we aimed at assessing both how DFMA can be integrated with computer simulation and the benefits from the alternatives identified by such method during production and assembly. Using as object of study the electronic voting machine printer, we identified options to improve design from principles of DFMA. The benefits are: reduction in assembly time and costs. As research method we used simulation, in which data were obtained by using direct observations, document analysis, and interviews with incumbents and users. Five models were composed to represent the current assembly process and two future models before applying amendments proposed by DFMA. The results show how effective the integration is with the DFMA simulation.

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Iso-Junno, Terho, Henri Niemi, Jarmo Mäkikangas, and Kari Mäntyjärvi. "Design Process of Durable and Lightweight Rally Car Frame from Ultra-High Strength Stainless Steel." Key Engineering Materials 786 (October 2018): 325–32. http://dx.doi.org/10.4028/www.scientific.net/kem.786.325.

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To get all outstanding mechanical properties from ultra-high strength steel (UHSS) transformed into a lightweight and durable product, a comprehensive design process must be performed. The general DFMA method has been extended to get good design solutions with limited designer resources and within a relative short time period. Key steps of the extended DFMA design process are innovative brainstorming, the agile utilization of the optimization software, the heavy use of finite element analysis and fast design iteration. In this paper, the modified DFMA design method is described step by step. This method has been successfully used in the design process of the small lightweight rally car frame. The design process of the rally car is introduced as a case example of implementation of the extended DFMA.

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Lohtander, Mika, Harri Eskelinen, and Juha Varis. "Review of Design for Manufacturing and Assembly Aspects to Designing Modern Micro-Wave and Sheet Metal Products." Key Engineering Materials 486 (July 2011): 9–12. http://dx.doi.org/10.4028/www.scientific.net/kem.486.9.

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In this paper, we present different points of view to make the sheet metal and micro-wave product as manufacturing friendly as possible. Within DFM(A)-research (Design for Manufacturing and Assembly), engineering design and manufacturability of Micro-Wave (MW) and sheet metal products has been studied. Other aspects of DFM(A) have risen from novel material applications and the development of CAD (Computer Aided Design) environments. In this paper, practical examples are presented to show how to apply DFMA-rules to MW- and sheet metal components, in particular, and how to develop DFM(A)-rules for these purposes.

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Wang, Xin Ting, Jun Xia Zhang, and Li Ping Yin. "Research of Electric Radiator Design Based on DFMA Method." Applied Mechanics and Materials 313-314 (March 2013): 11–14. http://dx.doi.org/10.4028/www.scientific.net/amm.313-314.11.

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Aimed at optimizing electric radiators design process, the enterprises expectationsmanufacturing technologies and market developing status were analyzed, then electric radiators key design restraining factors were summarized, design orientation was proposed finally. Based on this premise, a block-based electric radiator design scheme was presented with the Design For Manufacture & Assembly method (DFMA), then taking electric radiators key structure and part as an example , the application of DFMA in design practice was discussed in the view of coordinating the relation of product styling effect and structure design. Practices show that DFMA method is beneficial to improve design efficiency and feasibility.

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Zsók, János Csaba. "A DFMA gyártmányfejlesztő program alkalmazásának eredménye." Fiatal Műszakiak Tudományos Ülésszaka 1. (1996) (1996): 114–17. http://dx.doi.org/10.36243/fmtu-1996.28.

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Naiju, C. D. "DFMA for product designers: A review." Materials Today: Proceedings 46 (2021): 7473–78. http://dx.doi.org/10.1016/j.matpr.2021.01.134.

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Huang, Chih-Ming, Her-Yung Wang, Sing-Yuan Fang, and Wein-Duo Yang. "Influence of Fluorine-Containing Monomer Content on the Hydrophobic and Transparent Properties of Nanohybrid Silica Polyacrylate Coating Materials." Materials 14, no. 15 (July 30, 2021): 4261. http://dx.doi.org/10.3390/ma14154261.

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Nanosilica-modified, fluorine-containing polyacrylate hybrid coating materials, consisting of dodecafluoroheptyl methacrylate (DFMA), methyl methacrylate (MMA), 2-ethyl hexyl acrylate (2-EHA), 3-(trimethoxysilyl) propyl methacrylate (KH-570), and tetraethylorthosilicate (TEOS), are synthesized successfully by free radical polymerization and the sol–gel process. It is revealed that the content of the fluorine-containing polyacrylate hybrid coating materials from DFMA monomers significantly improves the properties of the films. The polyacrylate coating film prepared with a weight ratio of DFMA/MMA at 1:5 exhibits the largest water contact angle of 105.4°, which demonstrates that DFMA can effectively improve the hydrophobicity of the coating film. Moreover, the silicon coupling agent (KH-570) is used to graft silica with acrylate. Spherical in shape, the surface morphology of the nanohybrid film exhibits a core–shell structure, which increases the surface roughness and enhances the hydrophobic properties. The as-prepared fluorine-containing nanohybrid silica polyacrylate film possesses a high transmittance of 89–97% in the visible light region, indicating its potential as a very attractive solution in many practical areas.

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Purnomo Safaa, Yan, Jati Utomo Dwi Hatmoko, and Bambang Purwanggono. "Evaluation of the use of prefabricated bridge elements with Design for Manufacture and Assembly (DfMA) criteria." MATEC Web of Conferences 270 (2019): 05006. http://dx.doi.org/10.1051/matecconf/201927005006.

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The increasing need for bridge infrastructure in Indonesia requires an efficient and lean construction process. The aim of this research to evaluate the use of precast concrete elements on bridges based on the Design for Manufacture and Assembly (DfMA) criteria. DfMA is a principle design that considers the process of manufacture and assembly components based on the following criteria, i.e., simplificity of design, number of components, standardization on elements or material and ease of handling. Analytical Hierarchy Process (AHP) is used to determine the weights for each criteria. Data were collected through observations on a bridge project, interviews with engineers and questionnaires. A typical girder and slab bridge is used as an object for DfMA-based evaluation. The results of evaluation design of prefabricated components to recommend some that are suitable for use in bridge construction. The last case study was taken to one of the bridge construction projects on the newly completed highway is done to identify the prefabricated components used. Bridge analysis and re-design are carried out with the DfMA concept, including costs incurred, resource scheduling and discussions of project risk. The results of analysis with simulation design giving efficiency 28,83% simplificity of design; 8,74% number of components and standardization on elements or materials; 25% ease of handling; 51,53% assembly time; 23,39% cost of work and 18,87% duration time. Finally, the level of risk of work received such as weather conditions and work safety is reduced. In closing, recommendations were given for further DfMA development.

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Sudin, Mohd Nizam, Ngeow Sook Chin, Shamsul Anuar Shamsudin, and Mohd Asri Yusuff. "Design Efficiency Analysis Towards Product Improvement for Eco-Friendly Using DFMA Method." Open Mechanical Engineering Journal 10, no. 1 (October 27, 2016): 173–81. http://dx.doi.org/10.2174/1874155x01610010173.

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This paper presents the comparative study of design efficiency of two different brands of products, performing the same function using the Design for Manufacturing and Assembly (DFMA) method. The study aims to compare the products on the relative design efficiency. The DFMA method was used as it is a well-established technique for improving the efficiency of the product leading to minimizing production costs. It also shortens product development time by reducing the number of components in a product. The study used two different brands of dry iron as a case study. The result shows that the percentage of the design efficiency of dry iron A is 8.82%, whereas it is 10.34% of dry iron B. Thus, the dry iron B is much better as compared to A in term of its assembly operation and design efficiency. Therefore, the dry iron B is greener than dry iron A. Furthermore, a redesign of dry iron B was proposed and analyzed for the internal validation. The DFMA analysis result shows that the percentage of design efficiency of a new conceptual design of dry iron B increased to 18.08%. The application of the DFMA method to enhance the eco-friendliness of a product has been proven to be highly useful in design work.

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Antony, Kishore M., and S. Arunkumar. "DFMA and Sustainability Analysis in Product Design." Journal of Physics: Conference Series 1455 (February 2020): 012028. http://dx.doi.org/10.1088/1742-6596/1455/1/012028.

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Santosa, Irfan, Galuh Renggani Wilis, and Urip Mulyadi. "Soy Milk Filter Design Using Dfma Method." IOP Conference Series: Earth and Environmental Science 755, no. 1 (April 1, 2021): 012047. http://dx.doi.org/10.1088/1755-1315/755/1/012047.

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Zhou, Jian Hua, Lin Ben Wang, Yan Jiao Cui, Jian Zhong Ma, and Gen Xing Sun. "Synthesis and Properties of Nano-TiO₂ Modified Fluorine-Containing Polyacrylate Soap-Free Emulsion." Materials Science Forum 809-810 (December 2014): 161–68. http://dx.doi.org/10.4028/www.scientific.net/msf.809-810.161.

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Nano-TiO2Modified Fluorine-Containing Polyacrylate Soap-Free Emulsion was Successfully Synthesized via Soap-Free Emulsion Polymerization Technique, in which the Polymerization Monomers Consisted of Methyl Methacrylate (MMA), Butyl Acrylate (BA) and Dodecafluoroheptyl Methacrylate (DFMA). the Influence of Amount of Initiator, Emulsifier, Containing Fluorine Monomer and nano-TiO2on the Performance of Emulsion was Investigated. the Results Showed that the Good Polymerization Stability, and High Monomer Conversion were Obtained when the Amount of Ammonium Initiator was 1.2%, the Amount of Reactive Emulsifier was 3.5%. with Increasing Amount of DFMA, the Monomer Conversion Decreased and the Gel Rate Increased Gradually with the Increase of DFMA Amount. UV-Blocking Ability of the Cotton Fabric Treated with the Hybrid Emulsion Containing Nano-Tio2increased with Increasing Amount of Nano-TiO2. IR Spectrum Results Showed that Nano-TiO2and Fluorine-Containing Monomer were Successfully Introduced in the Segmental Structure of the Polymer. SEM Revealed that Nano-TiO2was Loaded on the Surface of the Treated Cotton Fabric which had Good Hydrophobicity.

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Ikhwanda, Rizky Syahrul, and Akmal Suryadi. "PENGEMBANGAN PRODUK ALAT PENGAYAK PASIR SECARA MANUAL DENGAN METODE DESIGN FOR MANUFACTURE AND ASSEMBLY (DFMA)." JUMINTEN 2, no. 4 (July 12, 2021): 37–48. http://dx.doi.org/10.33005/juminten.v2i4.290.

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Di zaman yang serba modern ini, sudah banyak alat pengayak pasir inovasi-inovasi baru yang diciptakan untuk memudahkan penggunanya dalam aktivitas sehari-hari. Akan tetapi, banyak produsen pengayak pasir yang fokus tertuju kepada produk yang efektif dan efisien. Banyak pekerja bangunan yang mengalami ke capekan dan ketidak nyamanan yang membutuhkan inovasi produk lebih dari pengayak pasir saat ini. Sementara itu pada saat ini tidak ada alat pengayak pasir yang efektif dan efisien dengan harga yang terjangkau. Pengayak pasir ini juga dirancang untuk mengurangi jumlah tenga kerja, sehingga produk ini memiliki nilai tambah di masyarakat. Untuk mewujudkan tujuan itu digunakan metode Design For Manufacturing And Assembly (DFMA). Design For Manufacturing And Assembly (DFMA) adalah suatu metode untuk perancangan dan pengembangan produk. Design For Manufacturing And Assembly (DFMA) juga didefinisikan oleh sebagai suatu metode terstuktur untuk melakukan perancangan dan pengembangan produk sesuai yang diinginkan oleh konsumen serta mengevaluasi secara sistematis kapabilitas suatu produk atau jasa untuk memenuhi kebutuhan konsumen.

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Liu, Quan, Wei Ming Tang, Yi Chi Chen, and Min Huang. "Synthesis and Basic Properties of Fluorinated Core-Shell Acrylic Latexes Containing Perfluoroalkyl Acrylate in the Shell." Applied Mechanics and Materials 339 (July 2013): 665–69. http://dx.doi.org/10.4028/www.scientific.net/amm.339.665.

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Fluoroacrylic copolymer latexes with core-shell structure were synthesized by free-radical emulsion copolymerization, using fluorine-containing acrylic monomer of dodecafluoroheptyl methacrylate (DFMA) and fluorine-free acrylic monomers. The chemical composition was characterized by Fourier transform infrared (FTIR) spectroscopy. The basic properties of the latexes including mainly hydrophobicity, chemical stability, chemicals-and corrosion-resistance were investigated. Significant improvement in the chemicals-and corrosion-resistance were observed for the fluorinated copolymer although only 5 wt% (based on the total monomers amount) of DFMA was copolymerized.

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Langston, Craig, and Weiwei Zhang. "DfMA: Towards an Integrated Strategy for a More Productive and Sustainable Construction Industry in Australia." Sustainability 13, no. 16 (August 17, 2021): 9219. http://dx.doi.org/10.3390/su13169219.

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Design for manufacture and assembly (DfMA) is an important part of the future of the construction industry due to the promise of speed of project delivery, quality control, worker safety, and waste minimization onsite via the purposeful design for manufacture and assembly offsite. However, the adoption of DfMA in Australia has been slow. This paper investigates the barriers prohibiting widespread uptake and how digital construction will be a catalyst for improving use on commercial-scale projects. A total of six leading experts were interviewed to elicit their opinions, and seven recent case studies of high-rise modular apartment and hotel buildings constructed by Hickory were cross-referenced as evidence of DfMA capability. The experts suggested that the reasons for slow adoption in Australia were community mindset, government regulations and incentives, planning and building codes, unionization and business politics, finance, and supply chain management. The case studies suggest that compatible building type and transportation distance are also factors. These barriers can be addressed by the clever integration of building information modelling tools with lean construction processes as part of a proposed strategy leading to smarter (more productive) and better (more sustainable) outcomes predicated on growth in digital construction practices. The paper concludes with a proposed framework for change that conceptualizes the ‘ecosystem’ needed to support widespread DfMA in the Australian context, including the paradigm shift from building to manufacturing/assembly, the displacement of workers from onsite to offsite activity, and the expansion of interdisciplinary design and construct collaboration.

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BROWN, T. R., T. S. EDRINGTON, K. J. GENOVESE, H. L. HE, R. C. ANDERSON, and D. J. NISBET. "Evaluation of the Efficacy of Three Direct Fed Microbial Cocktails to Reduce Fecal Shedding of Escherichia coli O157:H7 in Naturally Colonized Cattle and Fecal Shedding and Peripheral Lymph Node Carriage of Salmonella in Experimentally Infected Cattle." Journal of Food Protection 83, no. 1 (December 6, 2019): 28–36. http://dx.doi.org/10.4315/0362-028x.jfp-19-208.

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ABSTRACT Two experiments were conducted to evaluate the feeding of direct fed microbials (DFMs) on fecal shedding of Escherichia coli O157:H7 in naturally infected cattle (experiment I) and on Salmonella in the feces and peripheral lymph nodes (PLNs) of experimentally infected cattle (experiment II). Thirty cattle, 10 per treatment, were used in each experiment. Treatments in experiment I consisted of a control (lactose carrier only); DFM1, a 1:1 ratio of Enterococcus faecium and Lactobacillus animalis; and DFM2, a 1:1 ratio of Lactobacillus acidophilus and Pediococcus acidilactici. In Experiment II, DFM1 was replaced with DFM3, a 1:2 ratio of Lactobacillus reuteri and other Lactobacillus strains. Additives were mixed in water and applied as a top-dressing to each pen's daily ration for 50 days. Approximately half-way through each experiment, the DFM concentration was doubled for the remainder of the study. Fecal samples were collected throughout experiment I and cultured for E. coli O157:H7. Cattle in experiment II were inoculated intradermally with Salmonella Montevideo on days 32, 37, and 42 and then necropsied on days 49 and 50 (five cattle per treatment on each day). Innate immune function was assessed on days 29, 49, and 50. In experiment I, fecal concentration and prevalence of E. coli O157:H7 were not different (P > 0.10) nor was there an effect (P = 0.95) on the percentage of super shedders (cattle shedding ≥3.0 log CFU/g of feces). In experiment II, no treatment differences (P > 0.05) were observed for Salmonella in the PLNs except for the inguinal nodes, which had a significantly lower Salmonella prevalence in DFM-supplemented cattle than in the controls. Immune function, as measured by monocyte nitric oxide production and neutrophil oxidative burst, was decreased (P < 0.05) in the DFM treatment groups. Although results of this research indicate little to no effect of these DFMs on E. coli O157:H7 or Salmonella in cattle, an increase in the duration of administration to that similar to what is used for commercial cattle might elicit treatment differences. HIGHLIGHTS

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Lu, Ti, and Yi Du Zhang. "QFD&DFMA Application on an Oil/Water Separation Product." Applied Mechanics and Materials 163 (April 2012): 211–16. http://dx.doi.org/10.4028/www.scientific.net/amm.163.211.

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When oil fields become old, the proportion of water in crude oil will get higher and higher. Using a traditional bulk separator to extract the water from crude oil has many disadvantages: e.g. high pressure loss, low separation speed, heavy equipment and sensitive to direction. Caltec Ltd. has developed Wx-12, an innovative separator for the oil and gas industry. The device has been tested on offshore platforms and has shown high performance. Currently however, the manufacturing cost of the device is too high making it unlikely to be accepted by market. This project first used QFD to transform the user requirements of Wx-12 into engineering specifications. Then DFA & DFM methods were applied to Wx-12 in order to make it compact and reduce the manufacturing cost. An alternative design for Wx-12 unit was generated according to the results from QFD, DFA and DFM. Alternative materials were also considered to support the alternative designs. Finally alternative designs and alternative materials were verified with the engineers from Caltec Ltd..

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Pista, Ionut Madalin, Vasile Merticaru, and Marius Ionut Ripanu. "An integrated engineering solution used for enhancing the design of a technological device for automated assembly." MATEC Web of Conferences 178 (2018): 05007. http://dx.doi.org/10.1051/matecconf/201817805007.

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The paper presents a theoretical approach and a case study upon the use of an advanced CAD solution integrated with another engineering design software solution embedding DFMA concepts, particularly applied within the product and manufacturing process design for technological devices. The main objective of implementing CAD and DfX/DFMA integrated solutions is to guide designers into the product development phase so that a better design can be achieved in a shorter time and with lower costs. The case study analyzes an assembly model developed for an indexing mounting table dedicated for the automated assembling of an industrial electrical plug inlet. The assembly product model has been developed using 3D parametric modeling specific tools, further on it has been subjected to analysis based on DFMA principles and after that its components have been redesigned to respond to the analysis results. Some of the case study results and their interpretation are discussed in the paper content and finally some overall conclusions are included along with some intended future research directions.

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Violet Lozano, Marco Andrés, Harold David Agudelo Marmol, and Yahir Enrique González Dória. "Aplicación del método de diseño para manufactura y ensamblaje a un vehículo de tracción humana de tres ruedas como alternativa de transporte en la ciudad de Montería." Ingeniare, no. 24 (May 2, 2018): 109–23. http://dx.doi.org/10.18041/1909-2458/ingeniare.24.5174.

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Este trabajo presenta el diseño de un vehículo de tracción humana como alternativa de transporte sostenible en Montería, con el fin de reducir contaminación, ruido y mejorar la salud de los usuarios. Se empleó la metodología de diseño para manufactura y ensamble DFMA con el objetivo de reducir procesos de manufactura, complejidad en el ensamble y costos. Además, se realizó un análisis de esfuerzos en el chasis usando elementos finitos teniendo en cuenta las condiciones del terreno y las exigencias antivuelco definidas por ASME (2014). Los costos de fabricación se redujeron en 32 % comparado con un diseño anterior sin DFMA.

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Mäntyjärvi, Kari, Terho Iso-Junno, Henri Niemi, and Jarmo Mäkikangas. "Design for Additive Manufacturing in Extended DFMA Process." Key Engineering Materials 786 (October 2018): 342–47. http://dx.doi.org/10.4028/www.scientific.net/kem.786.342.

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As a new manufacturing method, Additive Manufacturing has begun to get a foothold in the manufacturing industry. The effective exploitation of the technology requires many times a re-design of the product or re-considering the manufacturing technology. Design for additive manufacturing differs considerably from design to other manufacturing methods, therefore design guidelines for additive manufacturing has been developed. The purpose of this paper is to present a new variant of the Design for Manufacturing and Assembly (DFMA) method which supports additive manufacturing.

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Dombrowski, Uwe, Hauke Tiedemann, and Ralf Borkowski. "Optimierung des Produktentstehungsprozesses mit Hilfe der DFMA-Methode." ZWF Zeitschrift für wirtschaftlichen Fabrikbetrieb 100, no. 10 (October 27, 2005): 595–98. http://dx.doi.org/10.3139/104.100951.

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Salim, M. S., M. A. Lajis, Z. C. Ros, A. Nawawi, S. Shamsudin, and N. K. Yusuf. "Redesigning of Agarwood Extracting Machine Applying DFMA Principle." IOP Conference Series: Materials Science and Engineering 637 (October 11, 2019): 012006. http://dx.doi.org/10.1088/1757-899x/637/1/012006.

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Subbaiah, Arunkumar, and Kishore M. Antony. "Integration of DFMA and sustainability - A case study." International Journal of Sustainable Engineering 14, no. 3 (January 18, 2021): 343–56. http://dx.doi.org/10.1080/19397038.2020.1871443.

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Abrishami, Sepehr, and Rocío Martín-Durán. "BIM and DfMA: A Paradigm of New Opportunities." Sustainability 13, no. 17 (August 26, 2021): 9591. http://dx.doi.org/10.3390/su13179591.

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The main goal of this study is to explore the adoption of a design for manufacturing and assembly (DfMA) and building information management (BIM) approach during the whole lifecycle of assets. This approach aims to tackle issues inherent in the design of traditional construction methods, such as low productivity and quality, poor predictability and building performance, and energy use, through the implementation of a BIM library of off-site components. In recent years, a renewed interest has been directed to the attempt to provide solutions to these urgent problems through the adoption of new advancements in technologies. However, while there are studies focussing on a BIM-DfMA approach, there is a lack of research regarding how this approach should be adopted during the whole lifecycle of the assets. Furthermore, to the best of our knowledge, defining an efficient way of developing a component-based BIM object library has not yet been included in any of the available studies. A mixed methodology approach has been used in this research. A conceptual framework was developed as the result of an extensive literature review to investigate new advancements in the AEC sector. Following the literature review, the framework was tested and validated through a case study based on the production and adoption of a BIM library of off-site components at the design stage of an asset. The architecture, engineering, and construction (AEC) industry has recognised the necessity of a new approach that helps to resolve the well-known issues presented in traditional methods of construction. The conceptual framework and case study proposed presents a valuable new method of construction that support the implementation of a BIM and DfMA approach, highlighting their benefits. This framework has been created using many valuable and reliable sources of information. The result of this research supports the idea of a novel new construction method that focuses on a manufacturing-digital-driven industry, with the use of DfMA in a BIM-integrated approach. This novel method will add significance and be beneficial for a wide range of aspects in the construction sector, contributing to the theoretical and practical domain.

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Hyun, Hosang, Hyung-Geun Kim, and Jin-Sung Kim. "Integrated Off-Site Construction Design Process including DfMA Considerations." Sustainability 14, no. 7 (March 30, 2022): 4084. http://dx.doi.org/10.3390/su14074084.

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Off-site construction (OSC) offers a promising means to improve the efficiency of construction projects. However, the lack of experience and knowledge regarding its use results in errors in design owing to conflicts and omissions of considerations for OSC projects. To mitigate these problems, the design for manufacturing and assembly (DfMA) is widely used to include the considerations in the OSC design process. Several studies concerning the DfMA application in OSC have been performed, but the comprehensive design process is not suggested for mitigating the aforementioned problems. This study proposes an OSC design process by integrating the fragmented DfMA considerations reported in previous studies. The considerations are identified through a systematic literature review and classified into structural and architectural types. To validate the proposed process, an OSC project design has been undertaken as a case study, wherein a significant portion of the building structure has been modified to comprise precast concrete (PC), instead of its reinforced counterpart, with a demonstrated reduction in the PC element design duration. The proposed process would guide and support the design process for reduction in the duration and errors incurred in the process. Moreover, the process can be considered a design guideline for the execution of future projects.

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Hao, Shuai, Lei Li, Wendong Cheng, Qiwen Ran, Yuyao Ji, Yuxuan Wu, Jinsheng Huo, Yingchun Yang, and Xingquan Liu. "Long-chain fluorocarbon-driven hybrid solid polymer electrolyte for lithium metal batteries." Journal of Materials Chemistry A 10, no. 9 (2022): 4881–88. http://dx.doi.org/10.1039/d1ta10728c.

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Xu, Tao, Qiangqiang Xiao, Jiayu Chen, Li Li, Xiongjun Yang, Lifang Liu, Wenhui Yuan, Bingjian Zhang, and Huijun Wu. "Hydrophobicity of Polyacrylate Emulsion Film Enhanced by Introduction of Nano-SiO2 and Fluorine." Polymers 11, no. 2 (February 3, 2019): 255. http://dx.doi.org/10.3390/polym11020255.

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This study proposes to utilize modified Nano-SiO2/fluorinated polyacrylate emulsion that was synthesized with a semi-continuous starved seed emulsion polymerization to improve the hydrophobicity, thermal stability, and UV-Vis absorption of polyacrylate emulsion film. To verify the proposed method, a series inspection had been conducted to investigate the features of the emulsion film. The morphological analysis indicated that Nano-SiO2 was surrounded by a silane molecule after modification, which can efficiently prevent silica nanoparticles from aggregating. Fourier transform infrared spectra confirmed that modified SiO2 and dodecafluoroheptyl methacrylate (DFMA) were successfully introduced to the copolymer latex. The particle size of latex increased with the introduction of modified Nano-SiO2 and DFMA. UV-Vis absorption spectra revealed that modified silicon nanoparticles can improve the ultraviolet shielding effect obviously. X-ray photoelectron spectroscopy illustrated that the film–air interface was richer in fluorine than film section and the glass side. The contact angle of modified Nano-SiO2/fluorinated polyacrylate emulsion containing 3 wt % DFMA was 112°, slightly lower than double that of polyacrylate emulsion, indicating composite emulsion films possess better hydrophobicity. These results suggest that introducing modified Nano-SiO2 and fluorine into polyacrylate emulsion can significantly enhance the thermal stability of emulsion films.

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Nasyitah Mohammad, Nor, M. F. Rosli, M. K. Fadzly, Nur Syaiyidah Mohamad Salikan, and M. S. M. Effendi. "Design for Manufacturing and Assembly (DFMA): Redesign of Joystick." IOP Conference Series: Materials Science and Engineering 864 (July 10, 2020): 012212. http://dx.doi.org/10.1088/1757-899x/864/1/012212.

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Emmatty, Francis J., and S. P. Sarmah. "Modular product development through platform-based design and DFMA." Journal of Engineering Design 23, no. 9 (September 2012): 696–714. http://dx.doi.org/10.1080/09544828.2011.653330.

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Naiju, C. D., Pranav V. Warrier, and V. Jayakrishnan. "Redesigning of Shopping Cart for Cost Reduction Using DFMA." MATEC Web of Conferences 95 (2017): 10003. http://dx.doi.org/10.1051/matecconf/20179510003.

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Venkatean, Govindarajalu, and Sadagopan Palaniswamy. "DFMA analysis of front axle assembly of an excavator." IOP Conference Series: Materials Science and Engineering 1059, no. 1 (February 1, 2021): 012057. http://dx.doi.org/10.1088/1757-899x/1059/1/012057.

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Marconnet, Bertrand, Frédéric Demoly, Davy Monticolo, and Samuel Gomes. "An assembly oriented design and optimization approach for mechatronic system engineering." International Journal for Simulation and Multidisciplinary Design Optimization 8 (2017): A7. http://dx.doi.org/10.1051/smdo/2016016.

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Today, companies involved in product development in the “Industry 4.0” era, need to manage all the necessary information required in the product entire lifecycle, in order to optimize as much as possible the product-process integration. In this paper, a Product Lifecycle Management (PLM) approach is proposed, in order to facilitate product-process information exchange, by considering design constraints and rules coming from DFMA (Design For Manufacturing and Assembly) guidelines. Indeed, anticipating these manufacturing and assembly constraints in product design process, reduces both costs and Time To Market (TTM), and avoids to repeat mistakes. The paper details the application of multi-objective optimization algorithms after considering DFMA constraints in a PLM approach. A case study using an original mechatronic system concept is presented, and improved by considering product-process integrated design, optimization and simulation loops, using numerical optimization and FEM (Finite Element Method) methods and tools.

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Giudice, F., F. Ballisteri, and G. Risitano. "A Concurrent Design Method Based on DFMA—FEA Integrated Approach." Concurrent Engineering 17, no. 3 (August 17, 2009): 183–202. http://dx.doi.org/10.1177/1063293x09343337.

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Zhang, Chongfu, Yangyang Yan, Tingwei Wu, Xiaoling Zhang, Guangjun Wen, and Kun Qiu. "Phase Masking and Time-Frequency Chaotic Encryption for DFMA-PON." IEEE Photonics Journal 10, no. 4 (August 2018): 1–9. http://dx.doi.org/10.1109/jphot.2018.2852299.

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Gonem, Omaro Fawzi Abdelhamid, Roger Philip Giddings, and Jianming Tang. "Timing Jitter Analysis and Mitigation in Hybrid OFDM-DFMA PONs." IEEE Photonics Journal 13, no. 6 (December 2021): 1–13. http://dx.doi.org/10.1109/jphot.2021.3121168.

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Živković, Srđan, and Dušan Ćurčić. "APPLYING DFMA TECHNIQUES IN THE DESING IN THE DESIGN AND MANUFACTURE OF WIND TUNNEL MODELS." International Journal "Advanced Quality" 45, no. 1 (June 19, 2017): 35. http://dx.doi.org/10.25137/ijaq.n1.v45.y2017.p35-40.

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Applying DFMA (Design for Manufacturing and Assembly) principles is crucial in the process of designing models for wind tunnel testing. The design process, especially of models for measuring the pressure distribution, takes several months. Production of these models require a minimum couple of months; sometime even more. The manufacturing with defects are not allowed. Very narrow time limits, defined by a contract, do not leave enough time for reworking. Very often, designers may not have knowledge of manufacturing rules and best practices - resulting in slower product development cycles, increased ECO/MCO (Engineering Change Order / Manufacturing Change Order), significant material waste and lower production yields. Manual reviews of Design or consultations with manufacturing experts are time consuming. Whole process need for proximity between design and manufacturing engineers. Design engineers need quick and interactive feedback while designing, integrated access to company’s manufacturing knowledge repository. This paper presents an automated application DFMA principles, applying the rules defined in the prototype production of wind tunnel models in Military Technical Institute.

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Mello, Carlos Henrique Pereira, Filipe Natividade Guedes, Carlos Eduardo Sanches da Silva, José Hamilton Chaves Gorgulho Júnior, and Amanda Fernandes Xavier. "Projeto conceitual de componentes de um forno industrial por meio da integração entre a engenharia reversa e o DFMA." Gestão & Produção 17, no. 3 (2010): 497–511. http://dx.doi.org/10.1590/s0104-530x2010000300005.

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O tema deste artigo é o estudo da integração da engenharia reversa (ER) e o projeto para manufatura e montagem (DFMA) como ferramentas de suporte ao projeto conceitual de produtos. A partir de uma fundamentação teórica sobre esses conceitos, o presente trabalho visa analisar a adequação de um modelo para a utilização integrada do DFMA com a prototipagem rápida em uma abordagem de ER no projeto de um novo sistema de fechadura para forno industrial e recomendar melhorias no projeto conceitual do novo sistema de fechadura. O método de pesquisa empregado foi a pesquisa-ação, uma vez que o pesquisador buscava resolver um problema identificado dentro do objeto de estudo em parceria com a equipe de profissionais da empresa. Os resultados das recomendações para o projeto conceitual apresentam redução, especialmente, no custo, no tempo para fabricação e no tempo para montagem. Conclui-se que o modelo de integração estudado foi adequado para apoiar o processo de projeto do sistema de fechadura proposto por meio da ER.

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Machado, Marina, Jason Underwood, and Andrew Fleming. "Implementing BIM to Streamline a Design, Manufacture, and Fitting Workflow." International Journal of 3-D Information Modeling 5, no. 3 (July 2016): 31–46. http://dx.doi.org/10.4018/ij3dim.2016070103.

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This paper presents a case study of BIM implementation for Design for Manufacture and Assembly (DfMA). The project is a Knowledge Transfer Partnership (KTP) between the University of Salford and Links FF&E, a design, manufacture and fit-out SME based in the UK. The project aims to implement BIM as a catalyst for a Lean transformation, streamlining process and operations. Initially, organisational process are reviewed, which is followed by implementing appropriate technologies to enable subsequent people and process transformation. The 30 month project is organized in 6 key stages. This paper presents findings from the first four stages that have been completed to date of 1. Establishing best practice knowledge in BIM; 2. Conducting a review and analysis of the organisation's current situation, 3. Developing a BIM-based collaborative strategy, and the fourth, which is currently progressing, 4. Pilot implementation of BIM collaborative strategy for DfMA. The remaining stages will conduct a project evaluation, before finally implementing an Enterprise Resource Planning (ERP) system.

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Flockton, Dean. "It's All in the Packaging." Mechanical Engineering 121, no. 02 (February 1, 1999): 58–59. http://dx.doi.org/10.1115/1.1999-feb-5.

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This article discusses it has become a basic assumption that prices do not rise but instead they should fall in the economics of electronic products. It was precisely to meet customers’ expectations of lower prices that a Canadian manufacturer went to an essentially mechanical redesign of a telecommunications device. Nortel’s work on the redesign followed the principles of a system called DFMA, or design for manufacture and assembly, a design analysis tool developed by Boothroyd Dewhurst Inc., Wakefield, RI. It enables product designers to pinpoint parts and assemblies that add unnecessary costs to a product, and then design to avoid them. DFMA is designed to give engineers a structured way to evaluate ease of assembly and the overall manufacturability of a product. Design for assembly requires the user to assess whether each part is necessary, and to consider the time and cost of assembling the product. Design for manufacture integrates information about manufacturing processes, allowing users to estimate manufacturing costs and make informed decisions about materials.

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Pinheiro, Nathália Marcia Goulart, Robert Eduardo Cooper Ordoñez, Gustavo Lemes Leite Barbosa, and Franco Giuseppe Dedini. "Computational simulation applied in choosing the best solution in a product development using design for manufacturing and assembly approach." Brazilian Journal of Operations & Production Management 15, no. 4 (November 25, 2018): 618–28. http://dx.doi.org/10.14488/bjopm.2018.v15.n4.a15.

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Highlights: The product development methodology aims to assist the planning and design of the product throughout its life cycle. Using selection criteria it is possible to choose a solution will be followed until the end of the development process and this process is known as optimization of product solutions. Design for Manufacturing and Assembly (DFMA) is an approach that allows selecting a product solution with better manufacturing and assembly performance. Computational modeling allows representing systems in virtual environment in order to reproduce its characteristics and to compare scenarios through simulation. Goal: The objective of this work was to apply the computer simulation to compare the productive performance, according to production times, productivity and resource utilization rate, of three solutions proposed for a raincoat for pets with thermal protection. Methodology: Initially, conceptual models representing the production systems for the three product solutions were generated. The systems were modeled in discrete event simulation software, enabling different scenarios testing, resulting in production performance indicators for each product solution. Results: The analysis of the performance indicators allow identifying that the third solution proposed for the product obtained the best productive performance in all proposed scenarios; therefore, it was chosen as the best solution for the product according to the DFMA approach. Limitations of the investigation: The application of the methodology indicated in this work was limited to the study of a single productive system of a specific product. Practical implications: This work presents a practical application of computer simulation tools applied to product development. Originality / Value: The original contribution of this work is the application of computational simulation of production systems in product development following the DFMA approach.

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Journal articles on the topic 'DFMA'

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