Log in

Relevant bibliographies by topics / DFP / Journal articles

To see the other types of publications on this topic, follow the link: DFP.

Journal articles on the topic 'DFP'

Author: Grafiati

Published: 4 June 2021

Last updated: 8 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'DFP.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Haux, R. "On Determining Factors for Good Research in Biomedical and Health Informatics." Yearbook of Medical Informatics 23, no. 01 (2014): 255–64. http://dx.doi.org/10.15265/iy-2014-0025.

Full text

Abstract:

Summary Objective: What are the determining factors for good research in medical informatics or, from a broader perspective, in biomedical and health informatics? Method: From the many lessons learned during my professional career, I tried to identify a fair sampling of such factors. On the occasion of giving the IMIA Award of Excellence lecture during MedInfo 2013, they were presented for discussion. Results: Sixteen determining factors (df) have been identified: early identification and promotion (df1), appropriate education (df2), stimulating persons and environments (df3), sufficient time

APA, Harvard, Vancouver, ISO, and other styles

2

Aydinok, Yesim, Patricia Evans, Aysen Terzi, Nurten Cetiner, and John B. Porter. "Randomised Prospective Evaluation of Iron Balance, Chelation Efficiency, Urine Excretion and NTBI Progression with Deferiprone (DFP) or Deferoxamine (DFO) Monotherapy or with Combined DFP Plus DFO." Blood 106, no. 11 (2005): 2698. http://dx.doi.org/10.1182/blood.v106.11.2698.2698.

Full text

Abstract:

Abstract Rationale. The relative effects of monotherapy regimes with oral DFP or sc DFO or combinations of these drugs, on chelation efficiency, iron balance, plasma non-transferrin bound iron (NTBI) and the proportion and speciation of urine iron, have not been compared previously in prospective randomised trials. By examining these variables together in a single study, insights into the effectiveness and mechanisms of action of mono or combination regimens can be gained. Design. A total of 25 patients (pts) with thalassaemia major were randomised into one of the following 3 arms: DFP (LIPOME

APA, Harvard, Vancouver, ISO, and other styles

3

Aydinok, Yesim, Amal El-Beshlawy, Claudia von Orelli-Leber, Claudia Czarnecki-Tarabishi, and Chantal Y. Manz. "A Randomized Controlled Trial Comparing the Combination Therapy of Deferiprone (DFP) and Desferrioxamine (DFO) Versus DFP or DFO Monotherapy in Patients with Thalassemia Major." Blood 108, no. 11 (2006): 557. http://dx.doi.org/10.1182/blood.v108.11.557.557.

Full text

Abstract:

Abstract Several clinical studies have shown that the combination of deferiprone (DFP) with desferrioxamine (DFO) is efficacious with regard to decrease in serum ferritin (SF), reduction of liver iron concentration (LIC) and increase in urinary iron excretion (UIE) in patients (pts) suffering from thalassemia major (TM). However, there is lack of randomized controlled trials comparing the efficiacy and safety of the combination therapy versus DFP or DFO monotherapy. This is the first randomized controlled trial analyzing and comparing changes of LIC and total iron excretion (TIE) in pts treate

APA, Harvard, Vancouver, ISO, and other styles

4

Maneekesorn, Supawadee, Hataichanok Chuljerm, Pimpisid Koonyosying, Chairat Uthaipibull, Yongmin Ma, and Somdet Srichairatanakool. "Identifying a Deferiprone–Resveratrol Hybrid as an Effective Lipophilic Anti-Plasmodial Agent." Molecules 26, no. 13 (2021): 4074. http://dx.doi.org/10.3390/molecules26134074.

Full text

Abstract:

Malaria i a serious health problem caused by Plasmodium spp. that can be treated by an anti-folate pyrimethamine (PYR) drug. Deferiprone (DFP) is an oral iron chelator used for the treatment of iron overload and has been recognized for its potential anti-malarial activity. Deferiprone–resveratrol hybrids (DFP-RVT) have been synthesized to present therapeutic efficacy at a level which is superior to DFP. We have focused on determining the lipophilicity, toxicity and inhibitory effects on P. falciparum growth and the iron-chelating activity of labile iron pools (LIPs) by DFP-RVT. According to ou

APA, Harvard, Vancouver, ISO, and other styles

5

Pepe, Alessia, Giuseppe Rossi, Antonella Meloni, et al. "Prospective Comparison on Cardiac Iron and Liver Iron by MR In Thalassemia Major Patients Treated with Combination Deferipron–Desferrioxamine Versus Deferipron and Desferrioxamine In Monoterapy." Blood 116, no. 21 (2010): 5164. http://dx.doi.org/10.1182/blood.v116.21.5164.5164.

Full text

Abstract:

Abstract Abstract 5164 Introduction: Using T2* MR a randomised placebo controlled study from Sardinia demonstrated combination therapy with deferiprone and desferrioxamine (DFP+DFO) significantly more effective than DFO in improving myocardial iron. One non-randomised study from Sardinia and one observational study from Greece seem to confirm for DFP+DFO therapy the most rapid clearance of cardiac iron. No data are available in literature about prospective comparisons on cardiac iron and function and liver iron in TM patients treated with DFP+DFO versus DFP and DFO in monotherapy. The aim of t

APA, Harvard, Vancouver, ISO, and other styles

6

Murana, A. A., K. Akilu, and A. T. Olowosulu. "Use of expanded polystyrene from disposable food pack as a modifier for bitumen in hot mix asphalt." Nigerian Journal of Technology 39, no. 4 (2021): 1021–28. http://dx.doi.org/10.4314/njt.v39i4.7.

Full text

Abstract:

This study evaluate the use of Disposable Food Pack (DFP) as a modifier for bitumen for an improved Hot Mix Asphalt (HMA). The bitumen was modified with 2%, 4%, 6%, 8% and 10% DFP obtained from domestic waste. The penetration, ductility and specific gravity of DFP modified bitumen decreased from 68mm to 59.5mm, 110cm to 101cm and 1.025 to 1.012 respectively with increase in DFP, while softening point increased from 49.5 oC to 54.5 oC with increase in DFP. The Marshal Stability results revealed that the DFP modified bitumen increased the stability values of the compacted mixes to a maximum of 9

APA, Harvard, Vancouver, ISO, and other styles

7

Morton, Ryan P., Paul D. Ackerman, Marc T. Pisansky, et al. "Prognostic factors for the incidence and recovery of delayed facial nerve palsy after vestibular schwannoma resection." Journal of Neurosurgery 114, no. 2 (2011): 375–80. http://dx.doi.org/10.3171/2010.5.jns091854.

Full text

Abstract:

Object Preservation of facial nerve function in vestibular schwannoma (VS) resections remains a significant operative challenge. Delayed facial palsy (DFP) is one specific challenge yet to be fully elucidated. The aim of this study was to evaluate DFP among VS resection cases to identify significant prognostic factors associated with its incidence and clinical recovery. Methods This investigation involves a retrospective review of 104 cases of VS resection that occurred between December 2005 and May 2007. Patients who developed DFP were compared with patients exhibiting no facial palsy postope

APA, Harvard, Vancouver, ISO, and other styles

8

Pepe, Alessia, Giuseppe Rossi, Antonella Meloni, et al. "A T2* MRI Prospective Survey on Heart and Liver Iron In Thalassemia Major Patients Treated with Sequential Deferiprone–Desferrioxamine versus Deferiprone and Desferrioxamine In Monotherapy." Blood 116, no. 21 (2010): 4259. http://dx.doi.org/10.1182/blood.v116.21.4259.4259.

Full text

Abstract:

Abstract Abstract 4259 Introduction: Most deaths in thalassemia major (TM) result from cardiac complications due to iron overload. No data are available in literature about possible different changes in cardiac and liver iron in TM patients treated with sequential deferipron–deferoxamine (DFP-DFO) versus deferipron (DFP) and deferoxamine (DFO) in monotherapy. Magnetic Resonance (MR) is the unique non invasive suitable technique to evaluate quantitatively this issue. The aim of this multi-centre study was to assess prospectively in the clinical practice the efficacy of the DFP-DFO versus DFP an

APA, Harvard, Vancouver, ISO, and other styles

9

Pepe, Alessia, Antonella Meloni, Giuseppe Rossi, et al. "Prospective Survey on Heart and Liver Iron and Heart Function in Thalassemia Major Patients Treated with Sequential deferiprone–desferrioxamine Versus Deferiprone and Desferrioxamine in Monotherapy." Blood 118, no. 21 (2011): 5298. http://dx.doi.org/10.1182/blood.v118.21.5298.5298.

Full text

Abstract:

Abstract Abstract 5298 Introduction: Magnetic Resonance (MR) is the unique non invasive suitable technique to evaluate quantitatively the changes in cardiac and hepatic iron and in cardiac function in thalassemia major (TM) patients under different chelation regimens. This study aimed to prospectively assess the efficacy of the sequential deferiprone–deferrioxamine (DFP-DFO) versus deferiprone (DFP) and deferrioxamine (DFO) in monotherapy in a large cohort of TM patients by quantitative MR. Methods: Among the first 1135 TM patients enrolled in the MIOT (Myocardial Iron Overload in Thalassemia)

APA, Harvard, Vancouver, ISO, and other styles

10

Chuljerm, Hataichanok, Supawadee Maneekesorn, Voravuth Somsak, Yongmin Ma, Somdet Srichairatanakool, and Pimpisid Koonyosying. "Anti-Malarial and Anti-Lipid Peroxidation Activities of Deferiprone-Resveratrol Hybrid in Plasmodium berghei-Infected Mice." Biology 10, no. 9 (2021): 911. http://dx.doi.org/10.3390/biology10090911.

Full text

Abstract:

Iron is essential for all organisms including fast-dividing malarial parasites. Inversely, iron chelators can inhibit parasite growth through the inhibition of DNA synthesis and can ameliorate oxidative cell damage. Deferiprone (DFP)-resveratrol (RVT) hybrid (DFP-RVT) is a lipophilic anti-oxidative, iron-chelating agent that has displayed potent neuroprotective and anti-plasmodium activities in vitro. The goal of this work was to investigate the inhibitory effects of DFP-RVT on parasite growth and oxidative stress levels during malaria infections. Mice were intraperitoneally infected with P. b

APA, Harvard, Vancouver, ISO, and other styles

11

Riou, C., A. Gargaros, G. Harichaux, et al. "15 SPERM STORAGE IN FEMALE REPRODUCTIVE TRACT: STUDY OF MOLECULES INVOLVED." Reproduction, Fertility and Development 27, no. 1 (2015): 100. http://dx.doi.org/10.1071/rdv27n1ab15.

Full text

Abstract:

Because of prolonged sperm storage in their oviduct, domestic hens can produce fertile eggs for up to 3 weeks following a single AI. The oviduct secretions may have an effect on sperm survival, but its composition during fertilization is unknown. In the present study, we compared the proteomic content of uterine fluid collected from two lines of hens divergent by their duration of fertility period (DFP), which defined sperm-storage duration. The first line displays a shorter period of sperm storage (10 days, line DFP–), whereas the second displays a longer period of sperm storage (21 days, DFP

APA, Harvard, Vancouver, ISO, and other styles

12

Delmaschi Ramos, Caroline, Carolina Veloso Lima, Mayara Dos Santos Noronha, Daylana Da Silva Pacheco, Bárbara Emanoele Costa Oliveira, and Pablo Guilherme Caldarelli. "Uso de diamino fluoreto de prata em crianças atendidas em uma unidade básica de saúde do norte do Paraná." Revista de Saúde Pública do Paraná 1, no. 1 (2018): 68–73. http://dx.doi.org/10.32811/2595-4482.2018v1n1.44.

Full text

Abstract:

O presente estudo avaliou o uso e a aceitação de diamino fluoreto de prata (DFP) em criançasatendidas em uma Unidade Básica de Saúde (UBS) do Norte do Paraná, bem como o cumprimento do protocolomunicipal para aplicação do DFP. Prontuários (n=43) de crianças de0 a5 anos residentes na área de abrangênciada UBS foram analisados. Foram coletadas informações sobre idade da criança, utilização e indicação do DFP,dentes submetidos ao tratamento e quantidade de reaplicações. Observou-se que o DFP foi aplicado em 79% das crianças devido à Cárie Precoce na Infância (CPI), 60% dos dentes que receberam a

APA, Harvard, Vancouver, ISO, and other styles

13

Li, Jialian. "The COST-UTILITY ANALYSIS OF FOUR CHELATION REGIMENS FOR Β-THALASSEMIA MAJOR: A CHINESE PERSPECTIVE". Mediterranean Journal of Hematology and Infectious Diseases 12, № 1 (2020): e2020029. http://dx.doi.org/10.4084/mjhid.2020.029.

Full text

Abstract:

Background: The four most commonly used chelation regimens for β-thalassemia major patients in China are a combination therapy of deferoxamine and deferiprone (DFO+DFP), deferoxamine(DFO) monotherapy, deferiprone(DFP) monotherapy and deferasirox(DFX) monotherapy. Such patients use iron chelators their whole lives, resulting in enormous treatment costs. This study analyses the cost-utility of these four regimens from the Chinese healthcare system perspective. Methods: A Markov decision model was used over a 70-year time horizon and was populated using clinical data from a systematic liter

APA, Harvard, Vancouver, ISO, and other styles

14

Heiss, Derik R., Donald W. Zehnder, David A. Jett, Gennady E. Platoff, David T. Yeung, and Bobby N. Brewer. "Synthesis and Storage Stability of Diisopropylfluorophosphate." Journal of Chemistry 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/3190891.

Full text

Abstract:

Diisopropylfluorophosphate (DFP) is a potent acetylcholinesterase inhibitor commonly used in toxicological studies as an organophosphorus nerve agent surrogate. However, LD50values for DFP in the same species can differ widely even within the same laboratory, possibly due to the use of degraded DFP. The objectives here were to identify an efficient synthesis route for high purity DFP and assess the storage stability of both the in-house synthesized and commercial source of DFP at the manufacturer-recommended storage temperature of 4°C, as well as −10°C and −80°C. After 393 days, the commercial

APA, Harvard, Vancouver, ISO, and other styles

15

Yuliani, Yuliani, Alberth Parlindungan, Marwati Marwati, and Krishna Purnawan Candra. "SENSORY RESPONSE OF WET NOODLES WITH SUBSTITUTION OF SUPER RED DRAGON FRUIT (Hylocereus costaricensis) PEEL." AGROINTEK 15, no. 2 (2021): 507–12. http://dx.doi.org/10.21107/agrointek.v15i2.7275.

Full text

Abstract:

Innovation in increasing the wet noodles performance was conducted by substituting super red dragon fruit (pitaya) peel (DFP) puree to get DFP wet noodles that have red color and rich in fiber. Wheat flour (WF) was substituted with super red DFP puree in a portion of 0-20%. A single factor experiment arranged in Completely Randomized Design with four replications for each treatment was conducted. Hedonic and quality hedonic properties for color, aroma, texture, and taste were determined. Data were analyzed by the Friedman test continued by the Wilcoxon Sign Rank test. The DFP wet noodle with D

APA, Harvard, Vancouver, ISO, and other styles

16

Eliana Lai, Maria, Stefania Vacquer, Alessia Pepe, et al. "Long-Term Outcome of Iron-Induced Cardiac Disease in Patients with Thalassemia Major Treated with Combined DFP/DFO or DFO Alone." Blood 108, no. 11 (2006): 1764. http://dx.doi.org/10.1182/blood.v108.11.1764.1764.

Full text

Abstract:

Abstract We conducted a 4-yr prospective trial to evaluate the long-term effects of combined deferiprone (DFP)/deferoxamine (DFO) on reversal of cardiac complications in thalassemia major compared to those of DFO alone. Twenty-eight patients (pts) with cardiac disease requiring medication were stratified according to their risk for cardiac death. Fourteen pts were high risk, serum ferritin (SF) > 2500 ug/L on two-thirds of occasions since the onset of cardiac disease. Of those with a SF < 2500 ug/L (low risk), six had progressive decrements of left ventricular ejection fraction (LVEF). N

APA, Harvard, Vancouver, ISO, and other styles

17

Lee, Jae Meen, Hye Ran Park, Young Doo Choi, et al. "Delayed facial palsy after microvascular decompression for hemifacial spasm: friend or foe?" Journal of Neurosurgery 129, no. 2 (2018): 299–307. http://dx.doi.org/10.3171/2017.3.jns162869.

Full text

Abstract:

OBJECTIVEThe authors investigated the incidence, clinical course, and predisposing factors associated with delayed facial palsy (DFP) following microvascular decompression (MVD).METHODSThe authors reviewed the records of 310 patients (311 cases) who were followed after MVD for hemifacial spasm (HFS). Of these patients, 45 (14.5%) developed DFP after MVD. The clinical characteristics and predisposing factors of the patients with HFS were investigated to identify prognostic factors that predicted the development of DFP after MVD. Log-rank tests were used to compare times to symptom disappearance

APA, Harvard, Vancouver, ISO, and other styles

18

Li, Jialian. "ECONOMIC EVALUATION OF CHELATION REGIMENS FOR β--THALASSEMIA MAJOR: A SYSTEMATIC REVIEW". Mediterranean Journal of Hematology and Infectious Diseases 11, № 1 (2019): e2019036. http://dx.doi.org/10.4084/mjhid.2019.036.

Full text

Abstract:

Background:Deferoxamine (DFO) or Deferiprone (DFP) or Deferasirox (DFX) monotherapy and DFO and DFP combination therapy were four commonly implemented now chelation regimens for the iron overloaded of β-thalassemia major. This systematic review aims to determine the cost-effectiveness of four chelation regimens and provide evidence for the rational use of chelation regimens for β-thalassemia major therapy in clinic.Methods:A systematic literature search in PubMed, EMBASE (Ovid), CENTRAL (Cochrane library), HTAD (Cochrane library), NHS EED (Cochrane library), CBM, CNKI, VIP, and Wanfang was con

APA, Harvard, Vancouver, ISO, and other styles

19

Chang, Stephano, Serge Makarenko, Ivan Despot, Charles Dong, Brian D. Westerberg, and Ryojo Akagami. "Differential Recovery in Early- and Late-Onset Delayed Facial Palsy Following Vestibular Schwannoma Resection." Operative Neurosurgery 18, no. 1 (2019): 34–40. http://dx.doi.org/10.1093/ons/opz083.

Full text

Abstract:

AbstractBACKGROUNDDelayed facial palsy (DFP) after resection of vestibular schwannomas (VS) is worsening of facial nerve function after an initially normal postoperative result.OBJECTIVETo characterize different types of DFP, compare recovery rates, and review of series of outcomes in patients following resection of VS.METHODSBetween 2001 and 2017, 434 patients (51% female) with VS underwent resection. We categorized the patients who developed facial palsy into groups based on timing of onset after surgery, immediate facial palsy (IFP), early-onset DFP (within 48 h), and late-onset DFP (after

APA, Harvard, Vancouver, ISO, and other styles

20

Mead, RJ, MG Feldwick, and JT Bunn. "1,3-Difluoro-2-Propanol: a Potential Replacement for 1080 in Fauna Management Programs in Australia." Wildlife Research 18, no. 1 (1991): 27. http://dx.doi.org/10.1071/wr9910027.

Full text

Abstract:

Administration to rats of 100 mg/kg of 1,3-difluoro-2-propanol (DFP), the major ingredient of the pesticide Gliftor, resulted in citrate accumulation in the kidney after a 3-h lag phase. Inhibition of aconitate hydratase in the kidney and the development of symptoms typical of sodium fluoroacetate (1080) poisoning in DFP-intoxicated rats suggested metabolism of DFP to (-)erythrofluorocitrate. The conversion of DFP to the toxic metabolite was found to involve defluorination by a microsomal mixed-function oxidase in the liver, induced by phenobarbitone and inhibited by piperonyl butoxide. Admini

APA, Harvard, Vancouver, ISO, and other styles

21

Gianoli, Gerard J. "Viral Titers and Delayed Facial Palsy after Acoustic Neuroma Surgery." Otolaryngology–Head and Neck Surgery 127, no. 5 (2002): 427–31. http://dx.doi.org/10.1067/mhn.2002.129817.

Full text

Abstract:

OBJECTIVE: Delayed facial palsy (DFP) after acoustic neuroma surgery has been reported to occur in up to one third of cases. Reactivation of latent virus has been proposed as an etiology for DFP. However, only retrospective case reports and case series have offered data to support this theory. The objective of this study was to correlate DFP with change in viral titers. PATIENTS AND METHODS: Twenty consecutive patients who underwent acoustic neuroma surgery were prospectively evaluated for viral titers immediately preoperatively and at 3 weeks postoperatively. Viral titers measured included he

APA, Harvard, Vancouver, ISO, and other styles

22

Sato, Akihiko, Masahiko Yamada, and Hiroshi Iwanami. "Estimation of the Proportion of Offspring Having Genetically Crispy Flesh in Grape Breeding." Journal of the American Society for Horticultural Science 131, no. 1 (2006): 46–52. http://dx.doi.org/10.21273/jashs.131.1.46.

Full text

Abstract:

Berry texture of grapes (Vitis labruscana Bailey, V. vinifera L., and their hybrids) can be characterized by two factors: 1) difficulty of breakdown in mastication and 2) firmness, which can be mechanically measured as deformation at first major peak (DFP) and maximum force (MF) of the force-deformation curve in flesh puncture tests. Crisp texture (easily breakable and firm flesh texture), one of the most important factors for the quality of table grapes, corresponds to a combination of small DFP (≤2.5 mm) and large MF (≥0.9 N). Obtaining offspring with crispy flesh is a primary objective in g

APA, Harvard, Vancouver, ISO, and other styles

23

Nazik, Hasan, John C. Penner, Jose A. Ferreira, et al. "Effects of Iron Chelators on the Formation and Development of Aspergillus fumigatus Biofilm." Antimicrobial Agents and Chemotherapy 59, no. 10 (2015): 6514–20. http://dx.doi.org/10.1128/aac.01684-15.

Full text

Abstract:

ABSTRACTIron acquisition is crucial for the growth ofAspergillus fumigatus.A. fumigatusbiofilm formation occursin vitroandin vivoand is associated with physiological changes. In this study, we assessed the effects of Fe chelators on biofilm formation and development. Deferiprone (DFP), deferasirox (DFS), and deferoxamine (DFM) were tested for MIC against a reference isolate via a broth macrodilution method. The metabolic effects (assessed by XTT [2,3-bis[2-methoxy-4-nitro-5-sulfophenyl]-2H-tetrazolium-5-carboxanilide inner salt]) on biofilm formation by conidia were studied upon exposure to DF

APA, Harvard, Vancouver, ISO, and other styles

24

Souza, Gabriela Dos Santos de, Aline Aparecida Schwanck, Rafael Inácio Barbosa, Alexandre Márcio Marcolino, and Heloyse Uliam Kuriki. "Eficácia de um protocolo de exercícios em cadeia cinética fechada para indivíduos com dor femoropatelar." ConScientiae Saúde 16, no. 4 (2017): 393–401. http://dx.doi.org/10.5585/conssaude.v16n4.7458.

Full text

Abstract:

Introduo: Acredita-se que resultados controversos quanto melhor abordagem teraputica para a Dor Femoropatelar (DFP) estejam relacionados a no padronizao dos voluntrios antes das avaliaes com relao ao nvel de estresse articular. Objetivo: Verificar a eficcia de um protocolo de fortalecimento para indivduos com DFP submetidos a um protocolo de estresse articular prvio s avaliaes a fim de padronizar os indivduos. Mtodos: Participaram 24 indivduos (14 DFP /10 controle). Utilizou-se testes ortopdicos, teste funcional step down, escalas e questionrios para dor e funcionalidade. O grupo DFP realizou

APA, Harvard, Vancouver, ISO, and other styles

25

Nadler, Melvin P., Robin A. Nissan, and Richard A. Hollins. "FT-IR and FT-NMR Study of Organophosphorus Surface Reactions." Applied Spectroscopy 42, no. 4 (1988): 634–42. http://dx.doi.org/10.1366/0003702884429463.

Full text

Abstract:

Fourier transform infrared (FT-IR) and Fourier transform nuclear magnetic resonance (FT-NMR) methods were used to examine the adsorption and reaction of diisopropyl fluorophosphate (DFP) on various solid adsorbents. Static and flow system experiments were monitored with the use of FT-IR to determine DFP adsorption rates and isotherms on silica, coated silicas, γ-alumina, coated aluminas, and activated charcoal. The adsorption of DFP(g) onto the solid adsorbents was generally very rapid, with a half-life of 20 s for 1 mg DFP onto 25 mg of 350 m2/g silica. The DFP adsorption isotherm on silica i

APA, Harvard, Vancouver, ISO, and other styles

26

Wu, Ding-Tao, Yun-Xuan Zhao, Huan Guo, et al. "Physicochemical and Biological Properties of Polysaccharides from Dictyophora indusiata Prepared by Different Extraction Techniques." Polymers 13, no. 14 (2021): 2357. http://dx.doi.org/10.3390/polym13142357.

Full text

Abstract:

In this study, different extraction techniques, including traditional hot water extraction (HWE), microwave-assisted extraction (MAE), pressurized assisted extraction (PAE), and ultrasonic-assisted extraction (UAE), were used to extract Dictyophora indusiata polysaccharides (DFPs), and their physicochemical and biological properties were compared. Results revealed that extraction yields of D. indusiata polysaccharides prepared by different extraction techniques ranged from 5.62% to 6.48%. D. indusiata polysaccharides prepared by different extraction techniques possessed similar chemical compos

APA, Harvard, Vancouver, ISO, and other styles

27

Pepe, Alessia, Antonella Meloni, Pasquale Pepe, et al. "Prospective Comparison on Cardiac and Hepatic Iron and Cardiac Function by MR in Thalassemia Major Patients Treated with Combination Deferiprone–Desferrioxamine Versus Deferiprone and Desferrioxamine in Monoterapy,." Blood 118, no. 21 (2011): 3194. http://dx.doi.org/10.1182/blood.v118.21.3194.3194.

Full text

Abstract:

Abstract Abstract 3194 Introduction: Using T2* Magnetic Resonance (MR) a randomized placebo controlled study from Sardinia demonstrated combination therapy with deferiprone and desferrioxamine (DFP+DFO) significantly more effective than DFO in improving myocardial iron. One non-randomized study from Sardinia and one observational study from Greece seem to confirm for DFP+DFO therapy the most rapid clearance of cardiac iron. No data are available in literature about prospective comparisons on cardiac iron and function and liver iron in TM patients treated with DFP+DFO versus DFP and DFO in mono

APA, Harvard, Vancouver, ISO, and other styles

28

Hillel, J., T. Schaap, A. Haberfeld, et al. "DNA fingerprints applied to gene introgression in breeding programs." Genetics 124, no. 3 (1990): 783–89. http://dx.doi.org/10.1093/genetics/124.3.783.

Full text

Abstract:

Abstract An application of DNA fingerprints (DFP) for gene introgression in breeding programs of both farm animals and plants is proposed. DFP loci, detectable by minisatellite probes, are extremely polymorphic. Individuals have unique patterns of DFP and thus can be selected for maximal genomic similarity to the recipient line, and minimal similarity to the donor line, using their DFP patterns as the criterion for similarity. This genomic selection (GS) can be performed at generations BC1, BC2 or both, and thus significantly reduce the required number of backcross generations in introgression

APA, Harvard, Vancouver, ISO, and other styles

29

Ammendola, Serena, Valerio Secli, Francesca Pacello, et al. "Salmonella Typhimurium and Pseudomonas aeruginosa Respond Differently to the Fe Chelator Deferiprone and to Some Novel Deferiprone Derivatives." International Journal of Molecular Sciences 22, no. 19 (2021): 10217. http://dx.doi.org/10.3390/ijms221910217.

Full text

Abstract:

The ability to obtain Fe is critical for pathogens to multiply in their host. For this reason, there is significant interest in the identification of compounds that might interfere with Fe management in bacteria. Here we have tested the response of two Gram-negative pathogens, Salmonella enterica serovar Typhimurium (STM) and Pseudomonas aeruginosa (PAO1), to deferiprone (DFP), a chelating agent already in use for the treatment of thalassemia, and to some DFP derivatives designed to increase its lipophilicity. Our results indicate that DFP effectively inhibits the growth of PAO1, but not STM.

APA, Harvard, Vancouver, ISO, and other styles

30

WU, GUANGJIAN, PEILIN LI, XUELEI ZHANG, and CHENGLONG ZHANG. "Using a geochemical method of dissolved and insoluble fractions to characterize surface snow melting and major element elution." Journal of Glaciology 64, no. 248 (2018): 1003–13. http://dx.doi.org/10.1017/jog.2018.87.

Full text

Abstract:

ABSTRACTA geochemical method to characterize post-depositional melting and elution is demonstrated using inductively coupled plasma mass spectrometry to measure concentrations of dissolved and insoluble fractions of major crustal elements in snow samples collected from March 2006 to January 2010 at Urumqi Glacier No. 1, Tien Shan. Dust from these samples has compositional homogeneity, suggesting that dust has a stable dissolved fraction percentage (DFP, calculated as dissolved/(dissolved + insoluble)%). Calcium has the highest DFP (averaging 61.5 ± 19.4%), followed by Na (30.4 ± 19.6%), Mg (13

APA, Harvard, Vancouver, ISO, and other styles

31

Zhao, Fei, Yong-Feng Wang, Lei Song, et al. "Synergistic Apoptotic Effect of D-Fraction From Grifola frondosa and Vitamin C on Hepatocellular Carcinoma SMMC-7721 Cells." Integrative Cancer Therapies 16, no. 2 (2016): 205–14. http://dx.doi.org/10.1177/1534735416644674.

Full text

Abstract:

The aim of this study was to investigate the anticancer effect of a combination of D-fraction polysaccharide from Grifola frondosa (DFP) and vitamin C (VC) on hepatocellular carcinoma in vitro. DFP is a bioactive extract from the maitake mushroom. Anticancer activity was demonstrated using various concentrations of DFP alone or in combination with VC against the human hepatocarcinoma SMMC-7721 cell line. To investigate the anticancer mechanism, studies designed to detect cell apoptosis were conducted. Results from the MTT assay indicated that a combination of DFP (0.2 mg/mL) and VC (0.3 mmol/L

APA, Harvard, Vancouver, ISO, and other styles

32

Milne, Dana, Joanna M. Hamilton, Debra McNeil, et al. "Everyone needs robust analytics: Integrating medical ontologies into the Dana-Farber Pathways." Journal of Clinical Oncology 37, no. 27_suppl (2019): 304. http://dx.doi.org/10.1200/jco.2019.37.27_suppl.304.

Full text

Abstract:

304 Background: The majority of clinical data is unstructured. Medical ontologies standardize the language used to communicate diagnoses, symptoms, and procedures used in healthcare. Incorporating medical ontologies into the Dana-Farber Pathways (DFP) provides structure and removes ambiguity by creating definitions for each data point. This exercise was critical for the development of the DFP into a fully automated platform that optimizes clinician workflow, reduces clicks, and expands the potential for data analysis. Methods: The DFP data model was reviewed to identify value sets contained in

APA, Harvard, Vancouver, ISO, and other styles

33

Pacora, Percy, Wilfredo Ingar, Ytala Buzzio, Manuel Reyes, and Miguel Oliveros. "Desproporción fetopélvica en un hospital de lima: prevalencia, consecuencias, predicción y prevención." Revista Peruana de Ginecología y Obstetricia 53, no. 3 (2015): 193–98. http://dx.doi.org/10.31403/rpgo.v53i1034.

Full text

Abstract:

OBJETIVO. Determinar las variables maternas y fetales que predicen la desproporción fetopélvica (DFP). LUGAR. Hospital Nacional Docente Madre-Niño San Bartolomé. DIISEÑO. Estudio clínico retrospectivo. PARTICIPANTES. Gestantes con detención del segundo estadio del parto y nacimiento por cesárea. INTERVENCIONES. Se revisó nuestra base de datos perinatales, del 1 de enero de 1991 al 31 de diciembre, 1999. Se definió DFP como la detención del parto durante 2 horas en nulíparas y 1 hora en multíparas, durante el segundo estadio del parto, y el nacimiento ocurrió por cesárea. Se realizó análisis de

APA, Harvard, Vancouver, ISO, and other styles

34

Sousa, Emerson Tavares de, Camila Lopes Crescente, Aline Laignier Yoshikawa, and Marinês Nobre-dos-Santos. "O diamino fluoreto de prata no controle da cárie na primeira infância durante a pandemia da COVID-19." Research, Society and Development 10, no. 6 (2021): e7710615380. http://dx.doi.org/10.33448/rsd-v10i6.15380.

Full text

Abstract:

Objetivo: Abordar aspectos de interesse clínico relacionados ao uso do diamino fluoreto de prata (DFP) no controle da cárie na primeira infância (CPI) durante a pandemia da COVID-19. Métodos: A busca para revisão de literatura foi executada na base de dados PubMed. Os descritores foram escolhidos pela importância na delimitação do tema e a síntese da literatura foi realizada de acordo com os tópicos: (1) efetividade clínica, indicações e limites do DFP e (2) uso clínico do DFP no contexto da COVID-19. Resultados: A pandemia da COVID-19 afeta todos os setores da sociedade, e, especialmente para

APA, Harvard, Vancouver, ISO, and other styles

35

Maggio, Aurelio, Angela Vitrano, Marcello Capra, et al. "Decrease of Mortality during Deferiprone Treatments: Results from A Large Randomised Cohort of Thalassemia Major Patients Under the Auspices of the Italian Society for Thalassemia and Hemoglobinopathies." Blood 112, no. 11 (2008): 3885. http://dx.doi.org/10.1182/blood.v112.11.3885.3885.

Full text

Abstract:

Abstract Prognosis of thalassemia major patients has dramatically improved in the past two decades. Previous papers, including retrospective and prospective non-randomised clinical trials, suggested that mortality, due mainly to cardiac damage, was less or completely absent in patients treated with DFP alone or with associated chelation treatment. For this reason, the main aim of this study was to evaluate whether the addition of deferiprone treatment was also associated with a mortality decrease among a large randomised cohort of thalassemia major patients. Survival analysis was performed amo

APA, Harvard, Vancouver, ISO, and other styles

36

Fiorillo, Marco, Fanni Tóth, Matteo Brindisi, Federica Sotgia, and Michael P. Lisanti. "Deferiprone (DFP) Targets Cancer Stem Cell (CSC) Propagation by Inhibiting Mitochondrial Metabolism and Inducing ROS Production." Cells 9, no. 6 (2020): 1529. http://dx.doi.org/10.3390/cells9061529.

Full text

Abstract:

Deferiprone (DFP), also known as Ferriprox, is an FDA-approved, orally active, iron chelator that is currently used clinically for the treatment of iron-overload, especially in thalassaemia major. As iron is a critical factor in Fe-S cluster assembly that is absolutely required for the metabolic function of mitochondria, we hypothesized that DFP treatment could be used to selectively target mitochondria in cancer stem cells (CSCs). For this purpose, we used two ER(+) human breast cancer cell lines, namely MCF7 and T47D cells, as model systems. More specifically, a 3D tumorsphere assay was empl

APA, Harvard, Vancouver, ISO, and other styles

37

Wang, Nan, Weiming Cheng, Min Zhao, Qiangyi Liu, and Jing Wang. "Identification of the Debris Flow Process Types within Catchments of Beijing Mountainous Area." Water 11, no. 4 (2019): 638. http://dx.doi.org/10.3390/w11040638.

Full text

Abstract:

The distinguishable sediment concentration, density, and transport mechanisms characterize the different magnitudes of destruction due to debris flow process (DFP). Identifying the dominating DFP type within a catchment is of paramount importance in determining the efficient delineation and mitigation strategies. However, few studies have focused on the identification of the DFP types (including water-flood, debris-flood, and debris-flow) based on machine learning methods. Therefore, while taking Beijing as the study area, this paper aims to establish an integrated framework for the identifica

APA, Harvard, Vancouver, ISO, and other styles

38

Zhao, Hong Jie, Zhen Hu, and Zhan Guo Li. "Degradation of Sarin Simulant DFP by Dielectric Barrier Discharge Plasma." Advanced Materials Research 781-784 (September 2013): 55–58. http://dx.doi.org/10.4028/www.scientific.net/amr.781-784.55.

Full text

Abstract:

The Dielectric Barrier Discharge plasma (DBD) plasma was used to treat Diisopropyl fluorophosphate (DFP, a stimulant of sarin) in the air. The influence factors of degradation efficiency, including power, carrier gas flow velocity and initial concentration of DFP were investigated. As a result, the degradation efficiency increased with the power increasing. The degradation efficiency increased fastly when the power less than 105W, but slowly when the power more than 105W. The degradation efficiency decreased obviously with the carrier gas flow velocity increasing, because the time of DFP staye

APA, Harvard, Vancouver, ISO, and other styles

39

Wong, Szu S., Søren Østergaard, Gareth Hall, et al. "A novel DFP tripeptide motif interacts with the coagulation factor XI apple 2 domain." Blood 127, no. 23 (2016): 2915–23. http://dx.doi.org/10.1182/blood-2015-10-676122.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Kantarjian, Hagop, Elias Jabbour, Guillermo Garcia-Manero, et al. "Results of a Phase I/II Study of DFP-10917, a Nucleoside Analog, Given By Continuous Infusion (CI) in Patients (pts) with Relapsed or Refractory Acute Leukemia." Blood 126, no. 23 (2015): 3804. http://dx.doi.org/10.1182/blood.v126.23.3804.3804.

Full text

Abstract:

Abstract Background: DFP-10917 is a nucleoside analog similar to cytarabine with a unique mechanism of action upon prolonged administration at a low dose. Under such administration, DFP-10917 is converted to its nucleotide form and then incorporated into tumor DNA to cause DNA strand breaks resulting in G2/M phase-arrest by cell-checkpoint regulators and ultimately the apoptosis of tumor cells. Methods: In Phase I, DFP-10917 was administered by 7-day CI followed by 21 days rest (P1-stage 1) or 14-day CI followed by 14 days rest (P1-stage 2) in pts with relapsed or refractory acute leukemia to

APA, Harvard, Vancouver, ISO, and other styles

41

Rao, Shalini S., Stuart D. Portbury, Larissa Lago, Ashley I. Bush, and Paul A. Adlard. "The Iron Chelator Deferiprone Improves the Phenotype in a Mouse Model of Tauopathy1." Journal of Alzheimer's Disease 77, no. 2 (2020): 753–71. http://dx.doi.org/10.3233/jad-200551.

Full text

Abstract:

Background: Abnormally hyperphosphorylated tau is a defining pathological feature of tauopathies, such as Alzheimer’s disease (AD), and accumulating evidence suggests a role for iron in mediating tau pathology that may lead to cognitive decline in these conditions. The metal chelator deferiprone (DFP), which has a high affinity for iron, is currently in clinical trials for AD and Parkinson’s disease. However, the effect of DFP on tau pathology remains underexplored. Objective: We aimed to investigate the impact of chronic DFP treatment on tau pathology using a well-characterized mouse model of

APA, Harvard, Vancouver, ISO, and other styles

42

Jahir, Syeda Jarka, Sayeeda Anwar, AKM Amirul Morshed, Afiqul Islam, and Kabirul Islam. "Comparative study of Deferiprone versus Deferiprone with Deferasirox as iron chelation therapy in Thalassemic children." Bangladesh Journal of Child Health 43, no. 3 (2020): 152–56. http://dx.doi.org/10.3329/bjch.v43i3.49571.

Full text

Abstract:

Background: Combination therapy of Deferiprone (DFP) with Deferasirox (DFX) is an efficacious and safe modality to reduce serum ferritin in multi-transfused children with thalassemia. Objectives: To compare the efficacy of Deferiprone versus Deferiprone with Deferasirox as iron chelation therapy of transfusion dependent thalassemia children. Materials and Methods: A non-randomized control clinical trial was done in department of Pediatric Hematology and Oncology, Dhaka Medical College Hospital and Bangladesh Thalassemia Hospital in Dhaka during the period of October 2016 to Septemb

APA, Harvard, Vancouver, ISO, and other styles

43

Xie, Keqin, Ram P. Gupta, and Mohamed B. Abou-Donia. "Effect of prevention and potentiation of diisopropyl phosphorofluoridate (DFP)-induced delayed neurotoxicity on the mRNA expression of neurofilament subunits in hen central nervous system." Biochemistry and Cell Biology 79, no. 2 (2001): 207–17. http://dx.doi.org/10.1139/o00-099.

Full text

Abstract:

Diisopropyl phosphorofluoridate (DFP) is an organophosphorus ester, which produces mild ataxia in 714 days and severe ataxia or paralysis in about 20 days (OPIDN) in hens. Previous studies in this laboratory have shown enhanced temporal expression of neurofilament (NF) subunit mRNAs in the spinal cord (SC) of DFP-treated hens. The main objective of this investigation was to study the effect of DFP administration on NF subunit mRNAs expression, when OPIDN is protected or potentiated by pre-treatment or post-treatment, respectively, with phenylmethylsulfonyl fluoride (PMSF). The hens were sacri

APA, Harvard, Vancouver, ISO, and other styles

44

Shi, Shuang Ji, Jia Zhi Lin, Zhu Ji Jin, Xiu Hong Zhong, and Bo Yin. "Fe Based Amorphous Alloy Used for Catalytic Machining Diamond Film." Advanced Materials Research 1027 (October 2014): 221–25. http://dx.doi.org/10.4028/www.scientific.net/amr.1027.221.

Full text

Abstract:

Diamond is a kind of ultra-hard and difficult-to-machine material. By means of the graphitization of diamond, dynamic friction polishing (DFP) technology is used to achieve a high-efficiency material removal of diamond. The polishing plate of DFP plays a key role in the process of polishing, and catalytic metal with unpaired d electrons is considered as ideal polishing material. To discuss and verify the feasibility that amorphous alloy can be used to polish CVD diamond film by DFP, Fe based amorphous alloy was prepared by mechanical alloying method and spark plasma sintering technology. The r

APA, Harvard, Vancouver, ISO, and other styles

45

Naess, Knut. "The Specificity of Diisopropylfluorophosphate (DFP)." Acta Pharmacologica et Toxicologica 12, no. 2 (2009): 154–63. http://dx.doi.org/10.1111/j.1600-0773.1956.tb01371.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Mendiratta-Lala, Mishal. "HCC Treatment Response DFP report." Abdominal Radiology 46, no. 2 (2021): 423–24. http://dx.doi.org/10.1007/s00261-020-02915-7.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Tricta, Fernando, Mariagrazia Felisi, Oscar Della Pasqua, et al. "Neutropenia in Children Treated with Deferiprone or Deferasirox: A Report of the Largest Randomized Trial of Oral Chelators in Transfusion-Dependent Pediatric Patients." Blood 134, Supplement_1 (2019): 3552. http://dx.doi.org/10.1182/blood-2019-127933.

Full text

Abstract:

Introduction: Agranulocytosis/severe neutropenia is an established adverse event during deferiprone (DFP) use. Less is known about milder episodes, which are frequently transient despite continuous deferiprone use. To provide further insight into this topic, we compared the incidence of neutropenia during DFP or deferasirox (DFX) treatment in the randomized Deferiprone Evaluation in Paediatrics (DEEP-2) trial, where blood neutrophil count was regularly monitored in patients randomized to be treated with DFP or DFX. Methods: DEEP-2 was a multicenter, randomized, 12-month, open-label trial compa

APA, Harvard, Vancouver, ISO, and other styles

48

Pepe, Alessia, Giuseppe Rossi, Antonella Meloni, et al. "A T2* MRI Prospective Survey on Heart and Liver Iron In Thalassemia Major Patients Treated with Deferasirox Versus Deferiprone and Desferrioxamine In Monotherapy." Blood 116, no. 21 (2010): 4267. http://dx.doi.org/10.1182/blood.v116.21.4267.4267.

Full text

Abstract:

Abstract Abstract 4267 Introduction: Most deaths in thalassemia major (TM) result from cardiac complications due to iron overload. In thalassaemia available three iron chelation regimes in monotherapy may achieve different changes in cardiac iron and function and liver iron. No data are available in literature about prospective comparisons on cardiac iron and function and liver iron in TM patients treated with deferasirox (DFX) versus deferiprone (DFP) and desferrioxamine (DFO) in monotherapy. Magnetic Resonance (MR) is the unique non invasive suitable technique to evaluated quantitatively thi

APA, Harvard, Vancouver, ISO, and other styles

49

Cháng, S., I. Despot, C. Dong, B. Westerberg, and R. Akagami. "F.03 Timing of incidence and recovery of delayed facial palsy after vestibular schwannoma resection: insight into mechanisms." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 43, S2 (2016): S19. http://dx.doi.org/10.1017/cjn.2016.98.

Full text

Abstract:

Background: Delayed facial palsy (DFP) after resection of vestibular schwannomas (VS) is described as worsening of facial nerve function after a normal postoperative result. Several mechanisms have been postulated to explain this phenomenon, although none satisfactorily explain all of its features. Furthermore, systematic documentation of recovery rates is lacking. Methods: 403 consecutive cases of VS resection between 2001 and 2015 were reviewed. Patients with preoperative facial palsy were excluded. Patients developing significant facial palsy (HB grade ≥ 3) were categorized into groups base

APA, Harvard, Vancouver, ISO, and other styles

50

Karote, Dennis, Brandon Walker, Huaien Dai, Ramaswamy Krishnamoorthi, Janis Voo, and Shyamala Rajagopalan. "Chemical Warfare Agent Simulants in Gamble’s Fluid: Is the Fluid Toxic? Can It Be Made Safer by Inclusion of Solid Nanocrystalline Metal Oxides?" Journal of Chemistry 2013 (2013): 1–14. http://dx.doi.org/10.1155/2013/641620.

Full text

Abstract:

The reactions of chemical warfare agent simulants, 2-chloroethyl ethyl sulfide (2-CEES) and di-i-propyl fluoro phosphate (DFP), in fluids have been investigated. Data analyses confirm the major degradation pathway to be hydrolysis of 2-CEES to 2-hydroxyethyl ethyl sulfide, along with minor self-condensation products. Among the three fluids examined, 2-CEES degradation was the fastest in Gamble’s fluid during a 96 h period. Upon addition of Exceptional Hazard Attenuation Materials (EHAMs) to 2-CEES containing Gamble’s fluid, degradation was generally improved during the first 24 h period. The 9

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!