Academic literature on the topic 'Dg260.a1 p53 2008'

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Journal articles on the topic "Dg260.a1 p53 2008"

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Hallaert, Delfine Y. H., Annelieke Jaspers, Carel J. van Noesel, Marinus H. J. van Oers, Arnon P. Kater, and Eric Eldering. "c-Abl kinase inhibitors overcome CD40-mediated drug resistance in CLL: implications for therapeutic targeting of chemoresistant niches." Blood 112, no. 13 (2008): 5141–49. http://dx.doi.org/10.1182/blood-2008-03-146704.

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Abstract In lymph node (LN) proliferation centers in chronic lymphocytic leukemia (CLL), the environment protects from apoptotic and cytotoxic triggers. Here, we aimed to define the molecular basis for the increased drug resistance and searched for novel strategies to circumvent it. The situation in CLL LN could be mimicked by prolonged in vitro CD40 stimulation, which resulted in up-regulation of antiapoptotic Bcl-xL, A1/Bfl-1, and Mcl-1 proteins, and afforded resistance to various classes of drugs (fludarabine, bortezomib, roscovitine). CD40 stimulation also caused ERK-dependent reduction of
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Ghia, Emanuela M., Michael Y. Choi, George F. Widhopf II, and Thomas J. Kipps. "ROR1-Signaling Increases Levels of Mutant TP53 Protein and Cyclin A1 Via Activation of NRF2, Potentially Potentiating Genomic Instability in Chronic Lymphocytic Leukemia Cells with Del(17p)." Blood 144, Supplement 1 (2024): 1852. https://doi.org/10.1182/blood-2024-211735.

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ROR1 is a developmentally-restricted receptor for Wnt5a, which can induce ROR1-signaling leading to expression of target genes induced by activation of ERK1/2, NF-κB, or NRF2 in leukemia cells of patients (pts) with chronic lymphocytic leukemia (CLL). Prior work found that expression levels of ROR1, and expression levels of target genes induced by ROR1-signaling, vary between pts; furthermore, pts with CLL cells with high-level ROR1 (ROR1Hi) were found to have a significantly shorter median time from diagnosis until initial therapy and overall survival than pts with CLL cells with low-levels o
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Dissertations / Theses on the topic "Dg260.a1 p53 2008"

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Pham, Mai. "Performance of Australian public and private hospitals." Phd thesis, 2008. http://hdl.handle.net/1885/110263.

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Given the importance of the Australian hospital industry, understanding the performance of public and private hospitals is essential for interested groups including patients, hospital staff, insurance companies and governments. Jn Australia, little information is available on hospitals' relative performance. Hence, studies investigating the issue are needed. This thesis addresses a part of this gap, in the context of hospital performance, investigating how public and private hospitals in Western Australia perform differently in terms of quality of care, and how Australian public hospita
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Books on the topic "Dg260.a1 p53 2008"

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Plutarch. Plutarch's lives. 2nd ed. Barnes & Noble, 2006.

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Plutarch. Fall of the Roman Republic. Penguin Books, 2005.

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Plutarch. Plutarch: The lives of the noble Grecians and Romans. Modern Library, 1992.

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Plutarch. Greek lives: A selection of nine Greek lives. Oxford University Press, 2008.

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Plutarch. Plutarch: The lives of Pompey, Caesar and Cicero : a companion to the Penguin translation from Fall of the Roman Republic published in the Penguin classics. Bristol Classic, 1991.

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Plutarch. Plutarch's lives / the Dryden translation, edited with preface by Arthur Hugh Clough ; introduction by James Atlas. Modern Library, 2001.

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Plutarch. Roman lives: A selection of eight Roman lives. Oxford University Press, 1999.

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Plutarch. Plutarch: Life of Kimon. Institute of Classical Studies, University of London, 1989.

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Plutarch. Roman lives: A selection of eight lives. Oxford University Press, 2008.

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Plutarch. Plutarch's Lives (Harvard Classics Collector's Edition, Vol. 12). Grolier Enterprises Corporation, 1987.

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