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1
Dr.Minal Shashikumar Vaidya and Geeta Parulkar. "Review on Modern Corelation of Asthimajja Kshya and Osteoporosis and Panchatikta Ghruta." Healer 2, no. 1 (2021): 87–94. http://dx.doi.org/10.51649/healer.22.
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Ayurveda is the science of life in which time tested treasure of knowledge which explains human body as a congential homeostasis of Dosha, Dhatu and Mala. The function of dhatus is dharana of the Sharira. Among all the dhatus, Asthi dhatu is responsible for function of sharira dharana.Equilibrium of dhatus is health and their disequilibrium is disease. This disequilibrium may either be increase or decrease. Asthi kshaya is a condition explained in Ayurveda, under the heading of ashtadasha kshayas. In Asthi kshaya there is abatement of Asthi dhatu. Similar to this, there is a condition known as Osteoporosis in modern medicine which means ‘Porosis in bones’ or ‘the brittleness of the bones due to increased porosity causing decrease in the bone tissue & leading to increased risk of fractures of any long and short bones. According to the principles of Aashrayaashrayi bhava, Asthi dhatu is the seat of Vata dosha and AsthiandVata are inversely proportional to each other regarding increase and decrease. Increase of Vata leads to decrease of Asthi. Here, an effort is made to critically analyse the concept of Asthikshaya mentioned in Ayurveda with corelation to Osteoporosis.
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Bola, Sunita, Mahesh Kumar Sharma, and Gyan Prakash Sharma. "A COMPARATIVE CLINICAL STUDY OF PANCHTIKTA KSHEERA BASTI AND ASTHI SANDHANIYA DRAVYA SIDDH KSHEERA BASTI IN ASTHI KSHAYA (OSTEOPOROSIS)." November 2020 08, no. 11 (2020): 4995–5003. http://dx.doi.org/10.46607/iamj0808112020.
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According to Ayurveda, diseases occur due to Dhatuvaishamyta & Dhatusamya maintains regularity. The Ashti Dhathu is the one consecrated with the role of Shareera Dharana among the Saptha Dhathus. As-thikshaya is the condition in which there is Kshaya of Asthi Dhatu. Asthi Kshaya may be compared to Os-teoporosis, in which there is a decrease in bone mass leading to bone brittleness and fractures. Asthi Kshaya is one of Dhatu Kshaya. Due to Dhatu Kshaya there will be Vata Prakopa hence in the treatment decreased Vata Dosha along with nourishing Asthi Dhatu essential. Basti is considered as the best Treat-ment for the Vata Dosha and Asthi Ashrita Vyadhi and is known as Ardhachikitsa in Ayurveda. Ksheera Basti nourished the Asthi Dhatu and pacified there its Asharya Vata Dosha. Aim & Objective-To assess the efficacy of Panchtikta Ksheera Basti and Asthi Sandhaniya Dravya Siddh Ksheera Basti in the man-agement of Osteoporosis. Material and Methods- present study was undertaken on 30 patients of Osteo-porosis. Patients diagnosed Osteoporotic by Bone Mineral Density test, were randomly divided into two Groups, A and B consisting of 10 patients each. Conclusion-The study shows that the Panchtikta Ksheera Basti and Asthi Sandhaniya Dravya Siddh Ksheera Basti are very effective in the management of Osteopo-rosis.
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Bola, Sunita, Mahesh Kumar Sharma, and Gyan Prakash Sharma. "A COMPARATIVE CLINICAL STUDY OF PANCHTIKTA KSHEERA BASTI AND ASTHI SANDHANIYA DRAVYA SIDDH KSHEERA BASTI IN ASTHI KSHAYA (OSTEOPOROSIS)." October - November 2020 p5, no. 01 (2020): 2554–62. http://dx.doi.org/10.46607/iamj02p5012020.
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According to Ayurveda, diseases occur due to Dhatuvaishamyta & Dhatusamya maintains regularity. The Ashti Dhathu is the one consecrated with the role of Shareera Dharana among the Saptha Dhathus. As-thikshaya is the condition in which there is Kshaya of Asthi Dhatu. Asthi Kshaya may be compared to Os-teoporosis, in which there is a decrease in bone mass leading to bone brittleness and fractures. Asthi Kshaya is one of Dhatu Kshaya. Due to Dhatu Kshaya there will be Vata Prakopa hence in the treatment decreased Vata Dosha along with nourishing Asthi Dhatu essential. Basti is considered as the best Treat-ment for the Vata Dosha and Asthi Ashrita Vyadhi and is known as Ardhachikitsa in Ayurveda. Ksheera Basti nourished the Asthi Dhatu and pacified there its Asharya Vata Dosha. Aim & Objective- To assess the efficacy of Panchtikta Ksheera Basti and Asthi Sandhaniya Dravya Siddh Ksheera Basti in the man-agement of Osteoporosis. Material and Methods- Present study was undertaken on 30 patients of Osteo-porosis. Patients diagnosed Osteoporotic by Bone Mineral Density test, were randomly divided into two Groups, A and B consisting of 10 patients each. Conclusion- The study shows that the Panchtikta Ksheera Basti and Asthi Sandhaniya Dravya Siddh Ksheera Basti are very effective in the management of Osteopo-rosis.
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Meend, Dr Sonia, and Dr Sunil Kumar Yadav. "Critical Analysis of Shukra Dhatu in Male and Female W.S.R to Post-Menopausal Osteoporosis in Females." International Journal for Research in Applied Science and Engineering Technology 11, no. 4 (2023): 4342–44. http://dx.doi.org/10.22214/ijraset.2023.51226.
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Abstract: Kshaya means “Swapramana Hani” i.e decrease in the quantity of the respective substance.1 Chakrapani dutta explains it as “Nyunatva” which means very less in amount. Acharya Vijayrakshita in Madhukosha Teeka has given detailed description about Pratiloma Dhatu Kshaya and also mentioned Swabhaava as one of the reasons for the Shukra Kshaya. When Shukra Kshaya occurs in a person, then Pratiloma Gati (movement) of Vayu occurs, due to which the first affected Dhatu is the Majja Dhatu. Shukra term denotes for both male and female Shukra, and not only male Shukra. Artava of female should also be considered here. Two forms of Shukra can be seen in the body. One is Dhatu Roopa, and other is the Beeja Roopa which are present in both male and female. The Beeja form of Shukra also has two components i.e Sthira Bhaga (Static) and Chala Bhaga (Dynamic) part. When Kshaya of Shukra is observed, both the forms i.e Dhatu and Beeja forms should be taken into consideration. This Kshaya of Shukra Dhatu again leads to Shosha of the Sneha Bhaga of body and leads to Pratiloma Gati of Vayu. This leads to the retrograde Kshaya of Dhatu. Due to this, Majja Dhatu gets affected first. This Majja Dhatu Kshaya has drastic effects on the Asthi Dhatu and leads to retrograde Kshaya, symptoms like Asthi Saushirya, Asthi Laghuta, Asthi Daurbalya etc. are markedly seen. These symptoms show striking similarity with the features of Osteoporosis.
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Bhairav B,, Tawshikar. "Efficacy of Panchatikta Ksheera Basti in Asthisoushirya (Osteoporosis)." Journal of Natural & Ayurvedic Medicine 4, no. 1 (2020): 1–4. http://dx.doi.org/10.23880/jonam-16000220.
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Osteoporosis a condition in which bones become weak and brittle can be co-related with Asthisoushirya that is Asthi majja dhatu kshaya. According to Charaka Asthisoushirya dealing with asthi majja dhatu kshaya can be corrected with Tikta Rasa, Kshir, and basti Vagbhata also thinks in the same direction. He advised Kshir, Ghrita and tiktabasti in Asthi kshaya. Therefore the aim of the study was to evaluate the efficacy of Panchatikta Ksheera Basti in Asthisoushirya. 30 patients of Asthi majja dhatu kshaya were treated with Panchatikta Ksheera Basti. Various parameters like pain, stiffness, tenderness, dosha-dhatu lakshan as were studied for the evaluation of therapy and the results were statistically analyzed. In present cast study, it was observed that patients treated with Panchatikta Ksheera Basti gives speedy recovery from symptoms of asthi majja dhatu kshaya. So we can conclude that Panchatikta Ksheera Basti capable in stabilizing the vitiated vata in Asthi majja dhatu and thus is beneficial in asthi majja dhatu kshaya
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Majumder, Bijita, and Sukalyan Ray. "A REVIEW ON VIKARA DHATU VAISHAMYAM’: AN APPRAISAL OF THE STATE OF DOSHAS AND DHATUS IN THE PATHOGENESIS OF DISEASES IN LIGHT OF CHARAKA SAMHITA." International Journal of Research in Ayurveda and Pharmacy 13, no. 5 (2022): 107–15. http://dx.doi.org/10.7897/2277-4343.1305136.
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As all the dosha, dhatu and mala are responsible for the retention of our body's homeostasis, all these three factors can be referred to as dhatu - ‘the element which holds up our body. Any deviation from the normal qualitative and quantitative state of these three elements can be referred to as dhatu vaishmaya, which is responsible for pathophysiologic changes in our body, which finally leads to the causation of diseases known as vikara. This deviation from the normal state can be in two ways - either in the form of aggravation/increment (known as vriddhi or prakopa) or regression/depletion (known as kshaya). In this article, the authors have tried to evaluate the state of dosha and dhatus during the pathological process of diseases, whether they remain in aggravated condition or depleted condition. From various textual understandings and evaluations of diseases' pathological processes and clinical features, it can be observed that dosha remains in its aggravated state during the pathogenesis of diseases and when it afflicts the dhatu - this results in the depletion of dhatu. Apart from two or three exceptions, in all types of conditions, this phenomenon of dosha vriddhi and dhatu kshaya can be observed conceptually as well as clinically. Thus, it can be concluded that the verse ‘Vikara Dhatu Vaishamyam’ refers to the altered state of dosha vriddhi and dhatu kshaya, which is responsible for the causation of vikara, i.e., diseases.
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Kumari V. and Khatri M. "A REVIEW ON ASHARYA ASHRAYI BHAVA RELATIONSHIP BETWEEN DOSHAS & DHATU W.S.R. TO ASTHIKSHAYA JANYA VATA VRIDDHI." International Journal Of Indian Medicine 04, no. 06 (2023): 01–08. http://dx.doi.org/10.55552/ijim.2023.4601.
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Ayurveda is the science of life that insists upon equilibrium state of all elements like Dosha, Agni, Dhatu, Mala, Atma, Mana, Indriya. The human body is made up of Doshas, Dhatus (tissue) and Malas (Excreta). These three entities are responsible for the maintenance of structural and functional integrity of body. The equilibrium state of these Dhatus results in Arogya, where as any imbalance in it produces Vikara. Among Dhatus, Asthi (bone) does Sharira dharan. The function of Asthi Dhatu is to support the body along with nourishing majja. Any upheaveal in equilibrium of Dhatus leads to disease. Asthikshaya is a condition described by Acharya Charak under 18 types of Kshaya. According to the principle of Ashraya-ashrayi bhava, Asthidhatu is the seat of Vata Dosha and inversely related to each other. Increase of Vata is the main factor responsible for Asthikshaya. Asthikshaya is condition in which there is Kshaya of Asthi Dhatu. It is a state where the functional capacity of Asthi is compromised due to decrease in its Guna, Karma and structure of Asthi. Understanding of Asharya Ashrayi Bhava is important because they have a working principle and supports the body frame.
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Rupali, Rupali Kapoor, Sakshi Chauhan, and Rajesh Kumar Manglesh. "A review article on types of Dhatu-Kshaya (depletion) and its clinical significance." Journal of Ayurveda and Integrated Medical Sciences 8, no. 12 (2024): 141–44. http://dx.doi.org/10.21760/jaims.8.12.22.
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Ayurveda is an old science that is very scientific and based on several fundamental principles. The science of life, or Ayurveda, categorizes the body's constituents within three essential elements Dosha (tissue entities), Dhatu (biological entities), and Mala, or waste materials. The balance between these entities is crucial to the durability and healthy lives for people. Similar to a progressive evolutionary metamorphosis, the production of Saptadhatus begins with the fundamental product of digestion, called Rasa Dhatu, and continues with the production of Rakta (blood tissue), Mamsa (muscle tissue), Meda (fat tissue), Asthi (bone tissue), Majja (bone marrow), and Sukra Dhatu (feces from reproduction). Every Dhatu is the basis for every other one and nourishes the one above it. The meals keep the steadily decreasing Dhatus in balance. That suggests the Dhatus are interdependent, with modifications to one causing modifications to the other. The goal of this review is to integrate different sources and arrive at a consensus. This paper explains the concept of Dhatu-Kshaya (depletion) in general terms and gives examples of how it can be used in real-world situations.
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Attarkar, Shubham, Dinesh Chandra Sharma, and Pooja Pareek. "A Review of Association between Mansa Dhatu Kshay and Contemporary Science." International Journal of Health Sciences and Research 15, no. 3 (2025): 56–59. https://doi.org/10.52403/ijhsr.20250310.
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Mansa Dhatu, or muscle tissue, is one of the seven Dhatu (tissues) identified in Ayurveda, which is essential for physical strength, stability, and structural support. Mansa Dhatu Kshaya (depletion) is marked by symptoms including muscle atrophy, weakness, weariness, and diminished endurance, indicating a decline in the body's essential structural integrity. This article rigorously analyses Mansa Dhatu Kshaya within the framework of modern medical science, linking it to disorders such as sarcopenia, cachexia, and muscular dystrophies. The significance of nutrition, metabolism, and hormonal equilibrium in sustaining Mansa Dhatu, along with their correlations to protein metabolism and muscle physiology, is examined. Additionally, Ayurvedic therapy, comprising food recommendations, herbal treatments, and rejuvenative therapies, are examined alongside modern therapeutic approaches. This integrative approach highlights the capacity of ancient wisdom to enhance contemporary medical methods in the treatment of muscle-related illnesses. Key words: Mansa Dhatu, Dhatu Kshaya, muscle atrophy, Ayurveda, sarcopenia, cachexia, muscular dystrophy, integrative medicine
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Komal Sandesh Gulakari and Ragini Patil. "Cross Sectional Observational Study of Rasa Dhatu Dushti in Known Diabetic Patients of Chronic Kidney Disease (C.K.D.)." Journal of Ayurveda and Integrated Medical Sciences 10, no. 4 (2025): 22–27. https://doi.org/10.21760/jaims.10.4.5.
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The rising incidence of CKD in Indian population is likely to pose major problems for healthcare and the economy in future years. In known diabetic patients of CKD, study of Rasa Dhatu Dushti is important for understanding the role of Rasa Dhatu in Samprapti of CKD. Aim is to assess Rasa Dhatu Dushti in known diabetic patients of chronic kidney disease on dialysis. Objectives are to assess Rasa Dhatu Kshaya, Vruddhi Lakshanas as per Vagbhata and Rasa Dhatu Dushti Lakshanas as per Charaka Samhita and analyse their severity as per the stages in known Diabetic patients of CKD on dialysis. Known diabetic patients of CKD on dialysis of age group 30-70 year and both genders were selected from dialysis centre. A Case Record Form was design for incorporating Lakshanas of different types of Rasa Dhatu Dushti. The stage of CKD is calculated on the basis of Sr. creatinine and Blood Urea reports collected from the patients. On the basis of grading of Lakshanas, the subjects are divided into Mild, Moderate and Severe Rasa Dhatu Vruddhi, Kshaya and Dushti Lakshanas. It is observed that Rasa Dhatu Kshaya, Vruddhi and Dushti remain highly prevalent across all CKD stages. More than 50 % of Rasa Kshaya Lakshanas were observed in 71 patients, Rasa Vruddhi Lakshanas in 40 patients and Rasa Dushti lakshanas in 7 patients. On the basis of outcome of observation and discussion, it is concluded that all types of Rasa Dhatu Dushti (predominantly Rasa Kshayatmaka Dushti) in all stages is present in known diabetic patients CKD on dialysis. Treatment of Rasa Dhatu is important to retard the disease progression.
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Bankar, Rahul Sukhdev. "Physiological Perspectives of Ashti Dhatu and Role of Basti Chikitsa towards the Health Restoration of Ashti Dhatu." Journal of Drug Delivery and Therapeutics 10, no. 1-s (2020): 218–20. http://dx.doi.org/10.22270/jddt.v10i1-s.3898.
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Asthi is one of the important Dhatu amongst the many other Dhatus of body which mainly involve in Sharira dharana function, it provide shape and physical built up of body and protect internal organs from external shock. The equilibrium of Asthi dhatus helps to restore normal health status while disturbed functioning of Asthi dhatus leads pathological states. The disturbance in Asthi dhatus may be Vriddhi or Kshaya that further leads many other bone disorders. The ayurveda described various approaches to restore physiological health of Asthi dhatus and Basti chikitsa is one of them. Considering thus present article summarizes physiological aspects of Asthi dhatus and role of Basti chikitsa towards the management of pathological disturbances related to the Asthi dhatus.
 Keywords: Ayurveda, Asthi dhatus, Basti chikitsa, Physiology
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Choudhary, Prakash, Rajesh Kumar Sharma, Dinesh Chandra Sharma, and Mukesh Saini. "A PHYSIOLOGICAL STUDY OF SHUKRA DHATU W.S.R. SEXUAL HORMONES." International Ayurvedic Medical Journal 9, no. 9 (2021): 2165–73. http://dx.doi.org/10.46607/iamj3809092021.
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Ayurveda has described three basic physiological constituents of the human body, viz., Dosha, Dhatu and Mala. In Ayurvedic Science, the one who has balanced Doshas, balanced Agni, properly formed Dhatus, proper elimina- tion of Malas, well-functioning of bodily processes and whose mind, soul, senses are full of bliss is called a healthy person1. So, the formation of Dhatu is also a good indicator of good health there are seven Dhatus ex- plained in Samhitas, those are Rasa, Rakta, Mamsa, Meda, Ashti, Majja and Shukra among all Dhatus, Shukra is considered as the sara of all other Dhatus2. Shukra Dhatu is one of the seven Dhatus in the body and Shukra is white, pure, excellent Dhatu, which is considered as best among all seven Dhatus. According to many Acharyas of Ayurveda, Garbhotpadana (reproduction) is the chief function of Shukra Dhatu, and the important fact is Shukra Dhatu also shows its effect all over the body in the form of Shukradhatusarata because Shukradhatuis located in the entire body. Sperm along with spermatic fluid and male sex hormones are also one part of Shukra Dhatu. Anu Shukra Dhatu (primordial germ cell) is essential for the Shukra Dhatu (Testosterone, Estrogen). Vi- tiation of Shukra dhatu shows Shukra dhatudusti (pathology) in the form of Vriddhi (hyper state) or Kshaya (wan- ing). This vitiation may lead to main infertility and many other physical as well as psychological disorders. All Dhatus have their definite locations in the body; they are present in every cell in subtle form. Every cell possesses the capacity to divide or reproduce itself. Thus, one has to interpret the Garbhotpadana (reproduction) function of Shukra Dhatu. In future, it may be achievable that with the development of the facts; we will discover any content in the cell whichpossesses a definite role in cell division.Sperms along with spermatic fluid and male sex hor- mones are also one Partofshukra, parallel to which females possess Artava. Stri-Shukra excreted during coitus is nothing but the secretions of bartholins, cervical and endometrial glands emergence at theendoforgasm. Keywords:Ayurveda, Stree-Shukra, Shukra Dhatu, Artava, hormones.
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., Ritesh, and Sandeep Kumar . "ROLE OF PANCHA TIKTA GHRITA GUGGULU ON MAJJA KSHAYA W.S.R. ERYTHROPOIESIS." Innovative Research Thoughts 3, no. 11 (2017): 689–95. http://dx.doi.org/10.36676/irt.2017-v3i11-119.
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Majja Dhatu is the body component similar to bone marrow, the soft organic material that fills the cavities of the bones. Bone marrow is composed of hematopoitic cells, marrow adipose tissue and supportive stromal cells. Bone marrow is primary site of new blood cell production or hematopoisis. According to ayurveda, only due to healthy majja dhatu, rakta sara & Majja sara purusha exists. When majja dhatu is in healthy state, best quality of hematopoisis occurs & nourishment of shukra dhatu takes place. Mridwanga, balavanta, snigdha varna & gambhira swara, sthula-dirgha vritta sandhayah and maha netra are the benefits occurs in majja sara purusha. In this clinical study, total 30 patients having the complaints of bhrama and timira darshanam as mentioned by acharyas in majja kshaya, the main symptoms of a majjakshaya related with poor erythropoiesis were treated with Panchatikta Ghrita Guggulu. Results proved that Panchatikta Ghrita Guggulu provided significant relief in the disease majja kshaya w.s.r. to erythropoiesis.
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Dr, Ritesh, and Sandeep Kumar Dr. "ROLE OF PANCHA TIKTA GHRITA GUGGULU ON MAJJA KSHAYA W.S.R. ERYTHROPOIESIS." Innovative Research Thaughts 3, no. 11 (2017): 7. https://doi.org/10.5281/zenodo.8082109.
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<strong>ABSTRACT </strong> Majja Dhatu is the body component similar to bone marrow, the soft organic material that fills the cavities of the bones. Bone marrow is composed of hematopoitic cells, marrow adipose tissue and supportive stromal cells. Bone marrow is primary site of new blood cell production or hematopoisis. According to ayurveda, only due to healthy majja dhatu, rakta sara & Majja sara purusha exists. When majja dhatu is in healthy state, best quality of hematopoisis occurs & nourishment of shukra dhatu takes place. Mridwanga, balavanta, snigdha varna & gambhira swara, sthula-dirgha vritta sandhayah and maha netra are the benefits occurs in majja sara purusha. In this clinical study, total 30 patients having the complaints of bhrama and timira darshanam as mentioned by acharyas in majja kshaya, the main symptoms of a majjakshaya related with poor erythropoiesis were treated with Panchatikta Ghrita Guggulu. Results proved that Panchatikta Ghrita Guggulu provided significant relief in the disease majja kshaya w.s.r. to erythropoiesis.
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Mohamed Muzzammel S, Bhumika S, and Dhivyashri S. "Ayurvedic perspective on Cancer: Conceptualization and Treatment." Journal of Ayurveda and Integrated Medical Sciences 9, no. 10 (2025): 95–98. https://doi.org/10.21760/jaims.9.10.14.
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Cancer, a multifactorial disease, continues to challenge modern medicine despite decades of research. Ayurveda, the ancient Indian system of medicine, presents a holistic approach to understanding and managing cancer by viewing it as a disorder of the Doshas (bodily humors), Dhatus (tissues), and Srotas (channels). This review explores how cancer can be interpreted through two key pathological states in Ayurveda, Dhatu Kshaya (tissue depletion) and Ojo Kshaya (vitality depletion), which lead to imbalances in the body’s homeostasis. By correlating cancer with conditions such as Srotoavarodha (blockage of channels) and Agnimandhya (suppressed digestive fire), this paper sheds light on Ayurvedic perspectives on carcinogenesis, metastasis, and therapeutic approaches like Virechana (purgation therapy). The review also discusses modern cancer pathophysiology and its correlation with Ayurveda, highlighting how integrative therapies can be used for effective cancer management.
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Bharti, Poonam Lata, Ruby Rani Agarwal, and Ila Tanna. "THERAPEUTIC EFFECT OF AMALAKI RASAYANA ON DHATU KSHAYA AND DHATU SARA IN PANDU ROGA." International Journal of Research in Ayurveda and Pharmacy 10, no. 6 (2019): 53–59. http://dx.doi.org/10.7897/2277-4343.1006124.
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C. S., Tanmane, and Akram Yusuf Khan. "REVIEW ARTICLE ON AYURVEDIC APPROACH SANDHIGAT VATA W.S.R. TO OSTEOARTHRITIS." International Ayurvedic Medical Journal 9, no. 8 (2021): 1882–87. http://dx.doi.org/10.46607/iamj04409072021.
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Ayurveda the science of life, healthy and higher longevity are always desirable from it. In today's modern era due to atmosphere, lack of proper healthy diet, travelling and old age etc. metabolic and degenerative disease of connective tissue and the joint problem is quite affluent, and the disease occurrence starts early. Sandhi- gatavata (Osteoarthritis) is a disease due to vitiated Vata in various Sandhi or joints in the body. It is de- scribed under Vatavyadhi in almost every literature of Ayurveda. Clinically the description of Sandhigata Vata explained in theclassical texts is like the condition osteoarthritis in modern science. Sandhigata Vata is described under Vatavyadhi in all the Samhitas and Sangraha Granthas. Ayurveda highlighted degenerative diseases under the concepts like “Dhatu Saithilyam” and “Dhatu Kshayam”. Sandhigata Vata is one such disease, which needs a specific target of therapeutic intervention to check or slow down the process of “Dhatu Kshaya” and to pacify Vata. Sandhigatavata may be correlated with degenerative joint disease or Osteoarthritis, which in turn cripples the patient to the maximum, extends and reduces the total working ca- pacity of the person. It limits everyday activities such as walking, dressing, bathing etc., thus making indi- viduals handicapped. Keywords: Sandhigatavata, Osteoarthritis, Joint, Vata Vyadhi.
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Kannalli, Prabhakar H., Shankara Gowda, Usha M, and Ravi R. Chavan. "A PHARMACEUTICAL ANALYTICAL STUDY OF MURCHITA GO-GHRITAM & CHAGALADYA GHRITAM." International Ayurvedic Medical Journal 9, no. 9 (2021): 1997–2005. http://dx.doi.org/10.46607/iamj1109092021.
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Ghee known as Ghritam, sarpish & Ajya, was used in ancient India as early as 1500 B.C. Rigveda, the oldest collection of Hindu hymns, contains numerous references to ghee, showing its importance in the Indian diet. The health benefits from ghee can be fundamentally categorized as those that are obtained from consuming ghee as food and those are obtained by using ghee as a medicine. Clarified milk fat or butterfat is known as ghrita. It is prepared by heating butter or cream to just over 100°C to remove water content. Goghrita is the best choice for food and medicinal purposes. So, in Ayurvedic classics and tradition, if not specified, the word ghrita always applies to goghrta. Chagaladya ghrita is one such classical, potent, unexplored, herbal preparation having properties of Jwara-prashamana (Antipyretic action), Dhatu-vriddhikara (Nourishes the Body tissues), improves mainly Mamsa dhatu, where dhatu kshaya is noticed in Rajyakshama Rogi by consuming of this Aja-Mamsa can restore the Mamsa dhatu kshaya (Mamsena Mamsa vruddhihi), also Increases body weight (Brimhanakaraka), Ojoskara (Immune- booster) indicated in the management of Rajyakshama presenting with predominant of Shwasa and Kasa. It contains mainly Chagamamsa (goat’s meat), Ashwagandha, Vasapanchanga, Chagadugdha and Goghrita and other Prakshepaka dravyas. Ghrita is one among the best Ajasrika Rasayanas. and is supreme in Snehana Dravyas. By its Yogavahitva, as per its ingredients, the medicated Ghrita will be attaining properties of the ingredients without forfeiting its properties. Keywords: Murchita Go-ghrita, Chagaladya Ghrita, Snehapaka, TLC
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Rawat, Renu, Rimpy Saini, Ruby Rani Agarwal, and Shashi Kant Tiwari. "ASSESSMENT OF RASA, RAKTA, MAMSA AND MEDO DHATU LEVEL IN HY-POTHYROIDISM." International Ayurvedic Medical Journal 13, no. 02 (2025): 417–21. https://doi.org/10.46607/iamj1713022025.
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Ayurveda, an age-old Indian medical system, is well-known for its natural remedies and comprehensive approach to wellness. Thyroid hormones are an essential part of the human endocrine system and play a significant role in the metabolism, growth and development of tissues. Thyrotropin-releasing hormone (TRH) produced by the hypothalamus acts on the pituitary to stimulate the synthesis and release of TSH. TSH stimulates the thyroid to secrete mainly T4 and T3. An increase in the level of thyroid hormones inhibits the release of TRH from the hypothalamus and TSH from the pituitary, while a fall in the level of thyroid hormones leads to an increase in the level of TRH and TSH. As per Ayurvedic doctrine, health and disease assessment are determined by the status of Agni, Dosha, Dhatu, Mala, and Srotas in the body. Metabolic activities are linked to the development and function of Dhatus, and it has been observed that hypothyroidism impairs this metabolism. Agni is fundamental to health and disease and is crucial to metabolism. Therefore, assessment of the Dhatu and agni is a key factor in determining the severity of hypothyroidism. The relationship between Dhatu Kshaya Vridhi and hypothyroidism can help in providing a new line of Ayurvedic treatment.
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Mukul Panwar, Jitendra Sankhala, Manoj Meena, and Shailendra Singh Mandloi. "A case study of Shukra Kshaya w.s.r. to Oligospermia." Journal of Ayurveda and Integrated Medical Sciences 8, no. 4 (2023): 207–10. http://dx.doi.org/10.21760/jaims.8.4.34.
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Male infertility is primarily caused by low sperm count (oligospermia) and reduced sperm motility (asthenospermia), which can be linked to Shukravaha Srotas Dushti and is an issue of global dimensions. Around the world, 8–12% of spouses struggle with infertility. Ten kinds of Shukra Dushti that cannot produce offspring have been described by Acharya Sushrut. The function of Shukra Dhatu according to modern aspects can be explained as reproductive strength of the person, in this Shukra means semen only. Factors affecting decrease of Shukra Dhatu leads to Shukra Kshaya can be co-related with oligospermia in males. Ayurvedic management was used to successfully treat a 36-year-old man who had been diagnosed with oligo-asthenospermia, a condition marked by low sperm count and non-motile spermatozoa. The man had been married for three years and his wife had a regular menstrual cycle. After Aamapachana, the aim of this case report is to evaluate the effect of Ayurvedic treatment in Shukra Kshaya which leads to male infertility. And its outcome reveals that the oligospermia associated with male infertility can be effectively managed by Ayurvedic treatments.
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Chauhan, Dr Lokesh, Dr Sakshi Bhardwaj, and Dr Abhinesh. "Prameha in Ayurveda: A Dhatu Kshaya Janya Vikara W.S.R. To Metabolic Disease." International Journal of Research Publication and Reviews 5, no. 11 (2024): 2397–403. http://dx.doi.org/10.55248/gengpi.5.1124.3244.
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Kumari, Priyanka, Guteri Meena, Chhaju Ram Yadav, and Sarika Yadav. "INTER-RELATIONSHIP OF MEDA DHATU DUSHTI AND ASTHI KSHAYA IN CONTEXT TO OBESITY." International Ayurvedic Medical Journal 11, no. 6 (2023): 1402–5. http://dx.doi.org/10.46607/iamj3111062023.
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Advanced technology leads to deprived health due to a stagnant lifestyle. Obesity is one such lifestyle disorder that is the precursor of several comorbid conditions. Health statistics link obesity with an increased risk of fracture which is an alarming issue and suggests the need to create awareness regarding the same. A high-fat diet, an inactive lifestyle, or a lack of physical activity impeded various metabolic pathways, changed the fate of cells from their normal destination, and affected bone homeostasis, according to the study. Aims and Objectives- Several recent studies have proposed that obesity is a risk factor for certain fractures indicating a strong contrary association between obesity and bone mineral density. The study is aimed to find the correlation between obesity and osteoporosis through a critical review. Methods- The material for this conceptual study is collected from various Ayurvedic texts, articles, online journals, etc. Discussion & Conclusion-When Meda Dhatu gets vitiated, then its Snigdha (unctuous) and Picchil (Viscid) qualities, obstructs the channel of circulation of tissue fluid, resulting in the deprivation of succeeding dhatu, i.e Asthi Dhatu. Excessive calorie intake and less calorie expenditure led to excessive accumulation of fat in the adipocyte causing its hypertrophy. Depending on the site i.e., abdominal or gluteofemoral hypertrophy of adipocyte, the severity of obesity-related complications observed.
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M, Kalatippi. "A Case Study on Management of Asthigata Vata W.S.R. AVN of Femoral Head." Journal of Natural & Ayurvedic Medicine 7, no. 1 (2023): 1–6. http://dx.doi.org/10.23880/jonam-16000378.
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Avascular necrosis of femoral head is a growing condition in the musculoskeletal clinic. This is mainly osteonecrosis caused by injury or occlusion in the blood vessels that supply bone tissue. AVN of femoral head is the most common type of necrosis because the artery that supplies this area is so narrow that it is easily injured, which then causes a lack of nutrition leading to necrosis. Modern medicine has no specific cures other than surgery. Moreover, it is expensive and unpredictable. In Ayurveda, Vata, Pitta, Rakta Dosha, Asthi, and Majja Kshaya play a major role in the pathogenesis of AVN. This article is aimed to nourish, repair, and regenerate Asthi Dhatu & Vatashamana. The current study, at the age of 28, diagnosed AVN of the femoral head was treated with Udvartana, Kshara Basti, Ksheera Basti, and Shasthika Shali Pinda Sveda which plays a significant effect in the improvement of pathology.
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Kumar Gupta, Shivjee, and Basant Kumar Thakur. "STUDY OF RAKTASARA PURUSH WITH SPECIAL REFERENCE TO COMPLETE BLOOD COUNTS." International Ayurvedic Medical Journal 11, no. 7 (2023): 1630–34. http://dx.doi.org/10.46607/iamj2411072023.
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Acharyas says that without the involvement of Dosas diseases would not manifest in the body. That's why it is necessary to understand the normal (equilibrium state) and abnormal (disequilibrium state) of Dosas in detail to know about physiological and pathological state of Dosas. The equilibrium state of Dosas is responsible for the maintenance of normal physiological functions. Seven types of Dhatu’s are described in detail namely Rasa, Rakta, Mamsa, Meda, Asthi, Majja, and Shukra. Seven types of Upadhatusare produced by the Dhatu’s during their metabolism are Stanya, Rajas (Rasa Dhatu), Kandara and Siras (Rakta Dhatu), Vasa and Sattvaca (Mamsa Dhatu), Snayu, Sandhi and Sveda (Meda Dhatu), Danta (Asthi Dhatu), Kesa (Majja Dhatu) and Ojas (Shukra Dhatu). The body gets nourished when the Dhatu’s are in equilibrium state.1 Dhatu’s may undergo Vriddhi (in-crease) or Kshaya (depletion) depending on the nature of causative factors and responsible various disorders. Bala means biological strength or power of resistance against diseases. It may be correlated with the immunity of an individual. As the predominance of particular Dhatu, the number of Dhatu Sara present in the body of an individual will be directly proportional to power of resistance of an individual2. That’s why Sarva Sara individu-al have relatively higher resistance in comparison to Madhyama and Avara (Sara) individuals. CBC is a set of medical laboratory tests that provide information about the cells in a person's blood. The CBC indicates the count of WBC, RBC and platelets; the concentration of Hb and the hematocrit (the volume percentage of RBC) the red blood cell indices which indicate the average size and Hb content of red RBC, are also reported, and a white blood cell differential, which counts the different types of WBC may be included.
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Shwetarani, Saranya K, and Nandesh Mohan P. "Overview of Leena Dosha and Sthambita Dosha." Journal of Ayurveda and Integrated Medical Sciences 8, no. 10 (2023): 182–85. http://dx.doi.org/10.21760/jaims.8.10.28.
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In Ayurveda Doshas are responsible for both health and disease in an individual. To cause any disease the Doshas should get vitiated. Doshas plays a major role in Dosha, Dhatu and Mala, as Doshas vitiate Dhatu and Mala leads to different Avastha of the Doshas. Diseases are manifested based on Avasthas of Doshas like Vriddhi, Kshaya, Prakopa, Upasthita Doshas. Similarly, the concept of Leenadosha and Sthambitadosha where the Leenadosha are said to be hidden or concealed or not completely seen hence they do not manifest Vyadhi, unless it attains favorable condition to manifest itself and Sthambitadosha is one among the Doshavstha where the Doshas are immoveable and it becomes stiff by obstructing the normal Gati of the other Doshas. There comes the importance of understanding the concept of Leenadosha and Sthambitadosha in detail for better diagnosis, treatment, and prevention.
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Shellgi, Vishal Kumar. "An observational study on Nidana of Janusandhigata Vata w.s.r to Knee Osteoarthritis." Journal of Ayurveda and Integrated Medical Sciences (JAIMS) 5, no. 03 (2020): 38–42. http://dx.doi.org/10.21760/jaims.5.3.7.
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Ayurveda, the holistic life science aims at physical, social and spiritual well-being of an individual. As age advances Vata Dosha increases in an individual. This increasing Vata triggers and accelerates Dhatu Kshaya (depletion of tissues) and Bala Kshaya (reduction of strength). Sandhigata Vata is a commonest disorder, occurs due to Dhatukshya. Vata Dosha plays a main role in the disease. Shoola is the cardinal feature of this disease, associated with Sandhishotha with Vatapurnadrutisparsha. Sandhigata Vata manifests when the deranged Vata lodges in joints. If the condition manifests in Janusandhi, then it is called as Janu Sandhigata Vata. In modern science, Sandhigata Vata is corelated with osteoarthritis (OA). Osteoarthritis is a chronic disorder of synovial joints in which there is a progressive softening and disintegration of articular cartilage accompanied by the growth of osteophytes. So here an effort was made in this study to understand the Nidana of Sandhigata Vata especially Janu Sandhi w.s.r to osteoarthritis of knee joint in all dimensions.
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B. R, Anagha, Madhushree H. S, and Ganesh Puttur. "SHODHANA IN PCOS-RELATED INFERTILITY." January 2024 12, no. 01 (2024): 134–40. http://dx.doi.org/10.46607/iamj21120120.
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Infertility is the inability to conceive in one or more years of regular unprotected coitus, and polycystic ovarian syndrome is a leading cause. Based on the pathogenesis, it is a Vata-Kaphaja Vyadhi with improper Agni. Symptomatically, PCOS is correlated to Artava-Kshaya and Pushpaghni Jataharani. Artava-Kshaya suggests Artavavaha Srotodushti, and Pushpaghni Jataharani refers to anovulatory cycles. Likewise, matured ovarian follicles are not expelled but converted to multiple cysts in PCOS. Hence, the management should be oriented in Agni Deepana and remove Srotosanga, for which Shodhana is considered the best. As there is Dushti in Kapha, Rasa, and Meda, Vamana Karma is indicated, followed by Virechana Karma for balancing the Pitta and Agni Deepana for Uttarottara Dhatu Poshana and Vatanulomana for correcting Apana Vayu aiding in the expulsion of Artava. Shodhana also improves the functioning of the Hypothalamo-Pituitary-Ovarian axis. Thus, PCOS-related infertility can be managed with Shodhana, Shamanoushadhi, and lifestyle modifications.
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Dangwal, Avdesh, Sujata Sharma, Shukla R.B., and Seema Joshi. "STUDY OF ANGULI PRAMANA OF SHADANGA - A REVIEW." International Ayurvedic Medical Journal 8, no. 9 (2020): 4467–71. http://dx.doi.org/10.46607/iamj2708092020.
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Pramana mean measurement that may be qualitative or quantitative. Qualitative measurement is based on character such as sex, education etc. But on the other hand, quantitative measurement is based on scale or unit of measurement. In Ayurveda, Anguli Pramana and Anjali Pramana are two types of measurement for different state of matter such as liquid and solid form. In humans Rasadi Dhatu are measured with the help of Anjali Pramana, in its contrast height, width and circumference are measured with the help of Anguli Pramana. Pramana are classically associated with health. Clinical implementation of Pramana may be helpful to assess the health of patient in sequence of Kshaya-Vridhi-Sama Awastha of Dosh, Dhatu, Mal and body parts in relation to his/her Anjali and Anguli Pramana. Anguli Pramana is important step in Dashvidh Aatur Pareeksha to assess physical health and to implement proper treatment according to the individual.
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Dr., Mane Shraddha M., and Kini Jai K. Vd. "View of an Eyeshot on Mridbhakshanjanya Pandu in Ayurveda." International Journal Of Ayurvedic And Herbal Medicine 14, no. 05 (2024): 4531–34. https://doi.org/10.5281/zenodo.13827752.
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<strong>ABSTRACT: </strong> Pandu Roga is a disease described in Ayurveda since immemorial, the first reference found in Vedas. Most of the Acharyas have described five types of Pandu Roga, i.e. Vatika, Paittika, Kaphaja, Tridoshaja, and Mridabhakshhana janya Pandu. Acharya Charaka, Vagbhatta, and Madhava have given a kind of Mridakabhakshanjanya of Pandu<sup>.</sup> Mridabhakshhana janya Pandu has a worldwide distribution, but the highest prevalence occurs in tropical & sub-tropical regions and areas with inadequate sanitation, Poverty, ignorance, lack of hygiene maintenance, bad sanitation and use of uncooked food or improper washing of food materials, eating soil, etc. are the important factors for spreading Mridabhakshhana janya Pandu in developing countries like India. When consumed, mud does not get digested in amashaya and blocks the rasavaha strotas. Due to this, gradually rasa dhatu kshaya takes place and in turn, the subsequent dhatu are not properly nourished, thereby producing Pandu roga.
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A. S, Sindhura, and Abdul Khader. "OSTEOARTHRITIS IN POST-MENOPAUSAL WOMEN – AN APPROACH THROUGH AYURVEDA." International Ayurvedic Medical Journal 04, no. 04 (2020): 2340–47. http://dx.doi.org/10.46607//iamjp0404122020.
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ABSTRACT Menopause is a gradual and natural transitional phase of adjustment between the active and inactive ovarian function and occupies several years of women’s life and involves biological and psychological changes adjustments. This period is usually associated with unavoidable manifestation of ageing process in women. With menopause, women enter an estrogen deficient phase in their lives, which accelerates the ageing process. Though Rajonivritti as a disease condition is not described separately in classical literature, Rajonivritti kala is mentioned by almost all classical texts. According to Sushrutha Samhita and other references too, 50 years is mentioned as the age of Rajonivritti, when the body is fully in the grip of senility. Sandhigata Vata is a most common condition which occur during this phase because of Dhatukshaya. Sandhigata Vata can be explained under the degenerative osteoarthritis according to contemporary science. Contemporary science suggests supplementation of estrogen as hormone replacement therapy in postmenopausal osteoarthritis. Sandhigata Vata in Rajonivritti has to be understood under Dhatukshayajanya Samprapti, which throws light into the utilization of Rasayana therapy, those specific to Asthidhatu Poshana in specific. Anupahata (unimpeded) dhatu Agni, Srotus and Vyana Vayu which is responsible for the sustenance of Sharira dhatu which is being fed by their poshaka dhatus, the derangement of which leads to hormonal disorders. This article aims at understanding the concept of Sandhigata Vata in Rajonivritti, considering Arthava Kshaya as the Nidana. Rasayana Chikitsa throws light into the scope of alternative therapy to hormone replacement therapy which works at the level of dhatu Agni, Srotus and Vyana Vayu. Application of phytoestrogens in such condition should also be considered as the supportive line of management. Keywords: Sandhigata Vata, Menopause, Estrogen, Rajonivritti, Rasayana, Osteoarthritis and Hormone Replacement Therapy (HRT)
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M. K, Manju Prasad, Mamatha Sri. S, and Nagendra Chary. M. "NEW PERSPECTIVE OF AJA KSHEERA W.S.R TO VRUSHYA ACTIVITY - A REVIEW." International Ayurvedic Medical Journal p6, no. 1 (2021): 3246–53. http://dx.doi.org/10.46607/iamj14p6012021.
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Shukra dhatu is meant for procreation, its Kshaya (diminution) causes Male Infertility. Shukra dhatu is formed by the transformation of Aahara rasa (food) with the help of Agni (digestive fire). Aahara is one of three important sub pillars which supports life. Ksheera is Satmya (wholesome), and it is Dhatu Vardhaka (nourishes the body tissues), Rasayana (rejuvenation), Vajikarana / Vrushya (aphrodisiac), generally indicated in Shukra Doshas (sem- inal disorders). Aja Ksheera (Goat milk) attributes Laghu (light), Balya guna (Strength promotor) along with Deep- ana (kindles the digestive fire), Grahi Karma (absorptive) praised for its Sarva-Vyadi Hara (cures all ailments) and Shukrala karma (spermatogenic measure). It is easily digestible when compared to Goksheera (cow milk) and it is a good source of essential fatty acids such as linoleic, vitamin A, and trace elements like Zinc, Mg which are essen- tial factors for the production of sperm and male hormone. Formulations of Aja Ksheeera namely Chagaladya ghrutha, Tilagokshuradi yoga possess Vrushya property and are indicated in Nastashukra (diminution of semen), Shukra Nisarana, Shanda (impotency) conditions. The Guna Karma of Aja Ksheera along with its rich nutritive value supports the spermatogenesis thus it can be considered in the treatment of Shukrakshaya as Aahara as well Aushadha. Keywords: Aja Ksheera, Goat Milk, Vrushya, Spermatogenic, Aphrodisiac
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Triveni, Dr Kumari. "Therapeutic Potential of Yashtimadhu (Glycyrrhiza glabra) in Demyelinating Disorders: An Ayurvedic Perspective." International Journal for Research in Applied Science and Engineering Technology 13, no. 6 (2025): 2248–53. https://doi.org/10.22214/ijraset.2025.72608.
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Demyelination involves the progressive destruction of the myelin sheath, leading to neurological impairment. In Ayurveda, such conditions correlate with Majja Dhatu Kshaya and Vata Vyadhi, particularly Pakshaghata, Ardita, and Kampavata. Yashtimadhu (Glycyrrhiza glabra), a Medhya Rasayana, has been traditionally used for Majjaposhana (nourishment of the nerve/marrow tissue), Vata shamanam, and balyakarma.This presentation is intendent to evaluate the therapeutic role of Yashtimadhu in the context of demyelinating neurological conditions.Method-Textual analysis from classical Ayurvedic compendia (Charaka Samhita, Ashtanga Hridaya, Bhavaprakasha) and supportive data from experimental and pharmacological literature were reviewed.Result and Discussion-Yastimadhu is described in ayurveda as balya, medhya, rasayana and vatapittahara making it a suitable drug in demyelination disorder. In this condition we need a drug which repairs myelin, restores nerve signal, rejuvenates tissue, reduce inflammation and improves immunity in ayurvedic terminology we need a drug which does majja dhatu poshana, vatashamana, rasayana therapy, pitta vata pacification and ojasvardhana respectively. Yastimadhu is one drug which can do all these work by its anti-inflammatory action, antioxidant and neuroprotective action as rich in flavaniods and saponin, balances immune system, promotes tissue regeneration and healing.Conclusion -Yastimadhu through its majja dhatu poshana, rasyana and vatashamaka action presents as a promising ayurvedic intervention in demyelinaton condition.
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Radhika Rani V and Mahesh Hirulal. "A review on etiopathogenesis of Santarpana and Apatarpana Janya Vyadhi." Journal of Ayurveda and Integrated Medical Sciences 8, no. 3 (2023): 129–33. http://dx.doi.org/10.21760/jaims.8.3.24.
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Santarpana and Apatarpana are the two types of effects in the body by the regular exposure to Brimhana and Langhana Ahara, Viharas respectively. In present scenario incidence of non-communicable diseases are increasing and are the risk factors for many systemic illnesses and mortality. A detailed understanding of non-communicable diseases is need of the hour. Those Dravyas which are predominant of Prithvi and Ap Mahabhoota will cause Brimhana and Dravyas which are predominant of Agni, Vayu and Akasha will cause Langhana. Santarpana Nidanas will vitiates predominantly Agni, Kapha and Meda leading for Santarpanotha Vikaras. From contemporary understanding these can be studied under over nutritive disorders. On the other hand, improper or excessive exposure to Apatarpana Ahara and Vihara leads to the vitiation of Vata and leads to increased Rookshata in Rasa Dhatu leading to Utharothara Dhatu Kshaya and manifesting the Apatarpana Janya Vikaras. These can be studied as nutritional deficiency disorders. Here an attempt is made to study the Santarpana and Apatarpana Nidana, Samprapti and Vikaras in detail.
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Venkataramanan, Sridhanya, Rajeshwari V Kamat, and Sanjay Ugare. "Molecular Mechanism of Nishamalaki as Rasayana in Diabetes Mellitus." International Journal of Ayurvedic Medicine 15, no. 2 (2024): 375–82. http://dx.doi.org/10.47552/ijam.v15i2.4552.
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Diabetes mellitus, a chronic non-communicable disorder, is on the rise in developing countries. In Ayurveda, a similar condition called Madhumeha is attributed to Dhatu kshaya (Emaciation) and Dosha avarana (occlusion of humoral factors). Rasayana therapy, involving herbal formulations like Nishamalaki, is recommended to strengthen the body's major structural components (dhatus), boost immunity, and promote longevity. Nishamalaki, a combination of Haridra (Curcuma longa Linn.) and Amalaki (Phyllantus emblica Linn.), exhibits antioxidant, anti-inflammatory, and lipid-reducing properties. It holds potential as a preventive measure to enhance the Quality of Life. The aim of this study was to validate the rejuvenation property of Nishamalaki in Diabetes mellitus using an insilico approach. Through tools such as SwissADME, SwissTargetPrediction, and Therapeutic Target Database (TTD), bioavailable components of Nishamalaki and Diabetes were analyzed, and a network was created using CytoScape. The results of the study identified two key compounds, Ellagic acid and Corilagin, which significantly modulate IGF1R and PTPN1, respectively, in Diabetes mellitus. These findings offer valuable insights into the potential therapeutic benefits of Nishamalaki in managing Diabetes mellitus and warrant further research and exploration in this area.
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B S, Nycy, Rajkumar Gupta, Priyal Bansal, and Utkarsha Khaire. "Ayurvedic management of Asthimajja gata vatarakta (Avascular necrosis of head of the femur) – A case report." International Journal of Ayurvedic Medicine 14, no. 2 (2023): 588–93. http://dx.doi.org/10.47552/ijam.v14i2.3451.
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Avascular necrosis is a condition where the bone tissue starts degenerating due to interrupted blood supply to the bone tissue. It is also known as ischemic bone necrosis, aseptic necrosis or osteonecrosis. From the contemporary medicine the management of AVN goes by pain management and joint replacement surgery. There is no direct correlation for AVN in Ayurveda. But concepts like Asthi kshaya, Asthi majja gata vata, Asthi majja gata Vatarakta symptoms stands very close to this disease condition. A female patient of age 42 came to the OPD complaining of pain in the bilateral hip joints with difficulty in walking since 6 months. MRI of the hip reveled grade 2 AVN of bilateral femur head. Patient was diagnosed as a case of Asthi majja gata Vatarakta with physical examinations. Pancha tikta ksheera kashaya, Lakshaguggulu, was given. Sandhaneeya mahakashaya gana Ksheera basti (enema with medicines processed in milk) was given to the patient for 14 days after sthanika snehana ans swedan . Pancha tikta ksheera kashaya has tikta and kashaya rasa. Tikta rasa has ashraya asharee bhava with asthi dhatu. Hence it improves the quality of asthi dhatu. Laksha guggulu helps in reducing the pain and improving the quality of rakta (rakta). Medicines included in Sandhaneeya mahakashaya gana are either Tikta, Kashya , Madhura. These rasa helps in reducing the rakta dushti (impaired circulation) and improves microcirculation. Ksheera basti helps in improving the quality of Asthi and majja dhatu. It also helps in reducing the pain in the affected region.
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Niveditha M N, Vasantha B, Muttappa Totad, and Adarsh Kallimath. "An Open Label Single Arm Clinical Study of Asthishrinkhala Ghrita Matrabasti and Asthishrinkhala Vati in Janusandhigatavata (Osteo-arthritis of knee)." Journal of Ayurveda and Integrated Medical Sciences 8, no. 11 (2023): 17–26. http://dx.doi.org/10.21760/jaims.8.11.3.
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Background: Osteoarthritis is the most common type of arthritis occurring in weight bearing joints like hip and knee. Main presenting symptoms are pain and functional restriction. With advancement in working pattern and age factor, it has become prime cause for aggravation of Vata Dosha, which does Dhatu Kshaya and Bala Kshaya leading to Sandhigatavata. Due to all these factors and being a Marma sthana, the person will be incapacitated from doing his day-to-day activities. Aims and objectives: To clinically evaluate the combined effectiveness of Asthishrinkhala Ghrita Matrabasti and Asthishrinkhala Vati in Janusandhigatavata. Methodology: In the present study, 34 patients of Janusandhigatavata fulfilling diagnostic criteria were given Asthishrinkhala Ghrita Matrabasti for 7days and Asthishrinkhala Vati for 21 days. Assessment were done using Visual Analogue Scale (VAS) for Pain, Ritchie articular index for assessment of tenderness, Swelling and crepitus based on numerical Scoring, Movement of joints measurement is done with Goniometer and physical functions assessed through WOMAC- Index for Osteoarthritis. Results: Data was analyzed using appropriate statistical test. Significant results (p<0.05) were found in all the cardinal symptoms- Vata Poornadruti Sparsha Shotha, Shula on Prasarana and Akunchana, Atopa and Stabdhata in Janusandhi. Conclusion: Asthishrinkhala Ghrita Matrabasti and Asthishrinkhala Vati is effective in management in Janusandhigatavata.
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Dupade, Vaishali Uday, and Laxmi M. Narhare. "EFFICACY OF GUDA AMALKI YOGA IN PITTAJ MUTRAKRUCCHA WSR CYSTITIS – A REVIEW STUDY." International Journal of Research -GRANTHAALAYAH 10, no. 4 (2022): 205–8. http://dx.doi.org/10.29121/granthaalayah.v10.i4.2022.4585.
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According to Ayurved, dosh, dhatu, mala are basic elements of human body. When they cross their normal limit i.e kshaya and vruddhi then disease starts to occur. In normal opd it is seen that pittaj Mutrakruccha is common disease. Modern lifestyle is responsible for such disease. Shoolyukta, Raktayukta, Dahayukta and muhurmur mutraPrawrutti is symptoms of pittaj Mutrakruccha.In modern, it can compare with cystitis. Burning micturition, dysuria, increases frequency of urination are main symptoms of cystitis. There are plenty of antibiotic and other medicines are available for that but it’s seen that, there is resistance comes for this medicine.There is description of Guda Amalaki Yoga in chakrdutta. Its simple ayurvedic formulation. As per it’s contain its useful drug on pittaj Mutrakruccha.It’s my review study which theoretically proves that efficacy of Guda Amalaki Yoga in pittaj Mutrakruccha.
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Bhalara, Bharat, and Joyal Patel. "A CLINICAL SUCCESS IN THE MANAGEMENT OF KOTHA (DIGITAL GANGRENE) BY LEECH THERAPYANDPANCHTIKTAGHRITAGUGGULU - A SINGLE CASE STUDY." International Journal of Advanced Research 9, no. 08 (2021): 668–72. http://dx.doi.org/10.21474/ijar01/13313.
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Gangrene is a type of tissue death caused by lack of blood supply. Symptoms may include a change in skin colour red or black, numbness, swelling, pain, ulceration and detachment of local skin. The feet and hands are most commonly affected. This condition may arise because of an injury, infection or other health conditions, majorly diabetes. Gangrene and its associated amputations are clinically challenging, but Ayurveda offers therapy options. In Ayurveda, gangrene can be considered as Kotha under DushtaVrana due to Margavarana and Dhatu Kshaya. This case study aims to investigate whether Ayurvedic intervention can manage Kotha (gangrene) without amputation of the gangrenous part. Here a case report disscused diagnosed with kotha(Dry Gangrene) treated with Ayurvedmanagenment,Panchtiktaghritagugguluoral and Jalaukavacharana (leech therapy), whichwere found very effective and safe in a patient of dry gangrene.
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Sahana T.N, Divya P, and Vardhaman Iraj. "Review article on Agni Pareeksha." Journal of Ayurveda and Integrated Medical Sciences 9, no. 5 (2024): 223–27. http://dx.doi.org/10.21760/jaims.9.5.37.
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Agni has been accorded prime importance by all the Acharya’s, as it plays a crucial role in the digestion, disease manifestation and overall health. The vitality, strength, and longevity of an individual depends on Agni. According to its site of action and the function Agni has been categorized into 13 types: Jataragni (1), Dhatvagni (7), Bhutagni (5). Acharya Vagbhata stated that all the diseases result from Mandagni, thus assessing Agni Bala is essential for understanding the pathogenesis (Samprapti) of the disease, planning treatment and determining prognosis. Anumana Pramana, Lakshana of Mandagni Vishamagni, Teekshnagni, Vyadhi based assessments can help to evaluate Jataragni, While the status of Dhatvagni can be inferred from the symptoms of Dhatu Vruddhi and Kshaya. Therefore, a physician’s path in treating a patient is significantly influenced by Agni assessment.
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Dr., Bharti Kalia, Shashi Singh Dr., Shweta Mishra Dr., and Ruchi Tiwari Dr. "Effect of Rasayan Therapy in Post-Menopausal Geriatric Females: A Holistic and Conceptual Approach." International Journal Of Medical Science And Clinical Research Studies 02, no. 11 (2022): 1281–83. https://doi.org/10.5281/zenodo.7322040.
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Menopause is just puberty’s evil sister. Geriatric women are passing through various physiological changes of body like premenopausal symptoms, perimenopause and post menopause. Menopause is a normal physiologic process in ageing women. Although many women over age 65 have persistent menopausal symptoms, there are limited data to guide therapy among older women. Approximately 9-16% of women over the age of 65 continue to have menopausal symptoms and 13.7% of those women are using some form of menopausal hormone therapy (HT). In geriatric age cognitive disturbance, urinary symptoms, vasomotor symptoms, psychogenic symptoms, sexual dysfunction, mood changes etc. have been linked to hormonal changes and increasing age among females. These changes are generally due to disturbed Vata dosha and Dhatukhaya. In geriatric women it is better to balance aggravated doshas so that the intensity of these diseases will be far less. This can be restrained with the unique therapeutic method known as Rasayana chikitsa which minimize the intensity of problems occurring during this phase of life. The focus of the article is to describe the pathophysiologic symptoms related to menopausal transition and to review the effect of rasayana therapy in geriatric women with special care of menopausal symptoms. If implemented properly Rasayana can give a better result instead of hormonal replacement therapy.
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Hima Mol V. and Prathima. "Understanding the influence of Manasika Bhavas on Stanya Kshaya: A Conceptual Study." Journal of Ayurveda and Integrated Medical Sciences 9, no. 8 (2024): 104–9. http://dx.doi.org/10.21760/jaims.9.8.15.
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Breast milk stands as the foremost source of nutrition in every individual's early life. According to Ayurveda, Stanya is considered an Upadhatu of Rasa and is pivotal for the nourishment and development of infants. Ayurveda defines decreased breast milk or lactation insufficiency as Stanya Kshaya, primarily attributed to emotions like anger, grief, and excessive affection, alongside dietary influences. Psychological factors such as emotional stress, anxiety, and maternal health also significantly impact milk production, necessitating both psychological and medical interventions. Any disruption in Agni affects Ahara Rasa, leading to disturbances in Rasa Dhatu, thereby affecting Stanya. Psychological aspects play a crucial role in the proper formation of Ahara Rasa. The significance of Manasika Bhavas lies in their advocacy of Soumanasya as a primary treatment for Ksheerajanana. This paper explores the correlation between psychological well-being and lactation outcomes, drawing on both contemporary psychological research and traditional Ayurvedic principles. Psychological stress, anxiety, depression, and maternal bonding are examined as key factors affecting hormonal balance and neuroendocrine pathways involved in lactation. Understanding these influences is crucial for holistic approaches to maternal health and breastfeeding support. The integration of psychological interventions alongside conventional medical treatments could enhance maternal lactation success rates and overall maternal-infant health outcomes. Thus, managing Stanya Kshaya requires thorough consideration of both psychological factors and dietary practices.
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Dubey, Sarvesh, Jyoti Dubey, and Lata Arya. "EFFECT OF INDIGENOUS DRUG IN THE MANAGEMENT OF VATASHTHILA W.S.R. TO BPH." International Ayurvedic Medical Journal 12, no. 10 (2024): 1828–33. https://doi.org/10.46607/iamj0312102024.
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Benign Prostatic Hyperplasia (BPH) is a common age-related disorder affecting millions of men worldwide. The conventional management of BPH involves pharmaceutical and surgical interventions, which have their own set of complications and limitations. In this context, the present study aimed to explore the efficacy of indigenous Ayurvedic drugs in managing Vatashthila (BPH). The study highlights the importance of considering the natural ageing process as a predisposing factor for BPH, as the classical Ayurvedic texts described. The Ayurvedic con-cept of Vatashthila, characterised by the predominance of Vata dosha and Dhatu Kshaya, is linked to the patho-physiology of BPH. The study also discusses the potential adverse effects of modern medicines and surgical procedures used to manage BPH. The present study suggests that indigenous Ayurvedic drugs may offer a safer and more effective approach to managing BPH, thereby reducing the risk of complications and promoting overall well-being.
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Pohiya, Ritu, Devjinder Singh, Pramod Kumar Mishra, and Indumati Sharma. "A REVIEW ARTICLE ON SANDHIGATA VATA." International Ayurvedic Medical Journal 12, no. 08 (2024): 1463–65. http://dx.doi.org/10.46607/iamj0712082024.
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Sandhigatavata is one such clinical entity among Vatavyadhi which affects the locomotion in which Dhatu Kshaya is the prime factor, which is characterised by specific symptoms like joint pain, swelling, stiffness, pain and restricted movement of joints, etc. Acharya Charaka and Vagbhaṭa have described the disease as Sandhigata Anil with Sandhisula (joint pain), Sandhishotha (swelling in joint), Prasarankuncanayoḥ Savedanahpravṛttiḥ (pain during movement like flexion and extension of the joints). Acharya Susruta and Mādhava have described that Hanti Sandhīn (loss of function) is the main symptom of Sandhigatavata. General Hetu of Vatavyadhi can be considered an etiological factor responsible for causing Sandhigatavata. Panchavidha kashaya kalpana can be effective in Kostha-gata or the primary condition of Sandhigatavata, Sneha Kalpna can be helpful in Shakhagata or moderately degenerative condition of Sandhigatavata and Guggulu Kalpana as well as Rasa Aushadhi can effectively treat the terminal or Marma-Asthi-Sandhigata stage of Sandhigatavata.
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Amle, Dr Deepali, and Dr Rutuja Gonge. "Conceptual literary study of Meda Dhatu Kshaya in Pandu Vyadhi with special reference hypolipidemia in iron deficiency anemia." Journal of Pharmacognosy and Phytochemistry 13, no. 5 (2024): 327–31. http://dx.doi.org/10.22271/phyto.2024.v13.i5e.15092.
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Yerme, Shilpa Prakashrao, Alka Bhandare, and Vaibhav Biradar. "A REVIEW LITERATURE OF TWAK SHARIR- W.R.T. RACHANA AND KRIYA SHARIR." Journal of Ayurvedic Herbal and Integrative Medicine 2, no. 1 (2022): 27–34. http://dx.doi.org/10.29121/jahim.v2.i1.2022.20.
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Ayurveda is an ancient & holistic system of medicine. Sushruta Samhita an oldest one Samhita of Ayurved. Acharya Sushruta in sharrer sthan has mentioned five Gyanendriyas (sense organs). skin, which is largest covering organ of body, in Ayurveda it comes under the term Sparshanendriya and adhishthana is Twacha (skin). Skin performs many functions like touch sensation, cold, temperature, pain, pressure, etc. skin serve to be first line of defense whatever we get into from environment the first response is from skin. Functions of all three dosha are well elaborated in the twak. Vata is responsible for carrying sensory input from twak to murdha by vyaan vayu, Piita in form of bhrajak pitta controls all the types of metabolic activities, and Kapaha regulates functions of sweat gland and sebaceous glands and maintains moisture. Being largest organ in the body it is also site of mana and rasa dhatu. Rasa dhatu kshaya is firstly and well elaborated in twak. Aging is the process that is well depicted in twak. Ayurveda advocates preventive and curative measure to control aging of twak.This article has been comprehended with all details about skin (twak) including Utpatti, synonyms, kriya, Rachna sharir of Twacha, types (layers) etc. skin is one of rog marg variety of diseases are observed on skin which are very unpredictable. Skin is not only rogmarg but also it is part of treatment modality. understanding twak an account with anatomy & physiology will help in various ways for diagnosis, prognosis, treatment etc.
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Nalawade, Sadhana, and Dnyaneshwar Padavi. "A CASE REPORT ON KATIGAT VATA WITH SPECIAL REFERENCE TO LUMBAR SPONDYLOSIS." Journal of Pharmaceutical and Scientific Innovation 11, no. 3 (2022): 36–38. http://dx.doi.org/10.7897/2277-4572.113231.
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According to Ayurveda Katigat vata is one of the types of Vata vyadhi explained in our ancient Ayurvedic text. It arises due to Prakop of Aata dosha and Asthi dhatu kshaya. Similarly Lumbar Spondylosis is a degenerative disorder affecting the discs and the vertebral bodies of the lumbar spine. Patients with lumbar spondylosis have pain in their axial spine which affects most of the people in the later stage of their lives. A 75 years old female having a history of katigat vata for the last 6 years so she approached Dr. DY Patil Ayurvedic Hospital for Ayurvedic management. Patient was having a progressive pain in her lower back with restricted movements. She was treated for 75 days including Panchakarma therapies. The response to the treatment was recorded and therapeutic effects were evaluated with a reduction of clinical symptoms of the patient. This case study evaluates that Ayurvedic management, in this case, was very effective treating Katigata vata successfully without any side effects.
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Chary. M, Nagendra, and Lalitha B.R. "COMPREHENSIVE CONCEPTUAL ANALYSIS OF SHUKRAVAHA SROTAS AND KSHEENASHUKRA (OLIGOSPERMIA) – AN OVER REVIEW." October - November 2020 p5, no. 01 (2020): 2601–5. http://dx.doi.org/10.46607/iamj08p5012020.
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Health and disease state of an individual is based on normalcy of a Srotas. Knowledge of Srotas plays an important role in diagnosing and management of every disease. The channel which carries Shukra is called Shukravaha Srotas. Srotosanga and Srotovaigunya are causes of Shukra Dusti and Shukra Kshaya. These are major reproductive issues result in male infertility. Acharya Charaka while listing qualities of Phalavat Shukra, Bahu (large in quantity) is one of the properties attributed to Shukra dhatu. Sufficient quantity of Shukra (Semen and Sperms) needed for reproduction. Deficient condition of Shukra is labeled as Ksheenashukra, is one of Shukra Dusti and correlates to Oligospermia- one of the seminal disorders and common causative factor for male infertility. Abnormal structures and functions of Shukravaha Srotas al-ter the production and ejaculation of Shukra. Hence an insight into Shukravaha Srotas is essential to treat Ksheenashukra. The present review elaborates relation between Shukravaha Srotas, Shukrajanana and Ksheenashukra.
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chaudhary, Ritu, Achyut acharya, Anirban singha, Kapil choudhary, Manita ahlawat, and Preeti gavali. "A COMPARATIVE STUDY OF VISHALADI CHURNA AND NISHA LAUHA IN THE MANAGEMENT OF PANDU." International Journal of Advanced Research 13, no. 04 (2025): 290–301. https://doi.org/10.21474/ijar01/20720.
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Background: Pandu Roga is a common yet significant disease described in Ayurveda, characterized primarily by vaivarnya (pallor) of the skin, mucosa, and eyes, resembling anemia in contemporary medicine. It is considered a manifestation of Rasa-Rakta Dhatu Kshaya (depletion of rasa and rakta dhatus), and its pathogenesis is deeply rooted in the improper functioning of Agni (digestive fire) and vitiation of Doshas, especially Pitta.The present study evaluates and compares the clinical efficacy of Vishaladi Churna and Nisha Lauha in the management of Pandu Roga. Materials and Methods:A randomized comparative clinical trial was conducted on two groups of patients diagnosed with Pandu Roga. A total of 98 patients diagnosed with Pandu were enrolled in the study. Out of these, 38 patients discontinued treatment before completion. Group A received Vishaladi Churna, and Group B received Nisha Lauhafor 3 days. Assessments were done before and after treatment using hematological investigations, the FACIT Fatigue Scale, and a standarized Ayurvedic pandutalakshana scoring scale.Results:Both groups showed statistically significant improvement (p < 0.0001) in all hematological parameters and subjective symptoms. Group B (Nisha Lauha) demonstrated superior improvement in Hb% (Ac%), RBC count, and cardinal signs like Panduta (88%) and Daurbalya (90.91%). It also showed greater relief in fatigue-related domains such as "I feel weak all over (83.51%) and I am able to do my usual activities(87.39%). Group A (VishaladiChurna) showed better improvement in symptoms related to social activity limitation and Pindikodweshtana (70.37%).
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-, Meenakshi. "A CASE STUDY: EFFECT OF KSHEERBALA TAILA JANUBASTI IN JA-NUSANDHIGATAVATA (OSTEOARTHRITIS)." International Ayurvedic Medical Journal 11, no. 7 (2023): 1767–70. http://dx.doi.org/10.46607/iamj5011072023.
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In Ayurvedic classics, Sandhigatavata is among eighty Nanatmaja Vata Vyadhi. As age advances, Vata Dosha increases in an individual. This increasing Vata accelerates Dhatu Kshaya (depletion of tissues) and Bala Kshaya (reduction of strength). Sandhigata Vata is a common disorder that occurs due to Dhatukshya. Sandhigatavata is the most common joint disorder worldwide. Shoola is the cardinal feature associated with Sandhishotha with Vatapurnadrutisparsha of this disease. If the condition manifests in Janusandhi, then it is called Janu Sandhigata Vata. Janusandhigatavata is also correlated to Knee osteoarthritis due to the resemblance in signs and symptoms, i.e., joint pain, stiffness, muscle weakness, swelling of the knee joint, deformed joint, reduced range of motion and loss of use of the joints and cracking sounds and progressive softening and disintegration of articular cartilage accompanied by the growth of osteophytes. The knee joint is weight-bearing, the strongest and most important joint in the body. Movements at the knee joint are essential for all everyday activities, including walking, running, sitting, and standing. Different modalities of treatment have been explained in the Ayurvedic classics to treat this disease. Here, an attempt has been made via Janubasti with Ksheerbala taila and Shallaki as Shamana Aushadhi. A patient XYZ of age 60years was treated with an External Panchakarma procedure, i.e., Janubasti with Ksheerbala taila for 12 days continuously, and oral medication was Shallaki started from the 1st day to the 12th day. Follow-up was done for 24 days to see improvement, and the patient got significant improvement in the sign and symptoms of the disease.
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Raj, Karthika, and Susheel Shetty. "A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF DARVYADI LEHYA AND DRAKSHADI LEHYA IN PANDU ROGA W.S.R TO I.D.A." International Ayurvedic Medical Journal 8, no. 9 (2020): 4324–28. http://dx.doi.org/10.46607/iamj0408092020.
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Pandu is a Pitta Pradhana Tridoshaja Vikara affecting the Rasavaha srotas causing Sapta Dhatu Kshaya and Ojokshaya1. The disease is characterized by Panduvamata and Arohana Ayasa. Karnakshweda, Agnimandya, Daurbalya, Annadwesha, Srama, Bhrama, Gathrashoola, Arohanaayasa, Aruchi, Gaurava etc. are the other symptoms commonly found in the patients of Pandu. In the Present era, Anaemia is a burning issue around the world and W.H.O Global data base 2011 reveals that, in a 120 million population, 83% people are suffering from anaemia2.Present study was conducted on 60 diagnosed patients of Panduwho were randomly allocated with 30 each in two groups. Darvyadhi Lehya was given for one group and Drakshadhi Lehya a widely used formulation in clinical practice was given for another group. The study was conducted in 60 subjects for a period of 30 days. Clinical features and haematological parameters were documented before and after the treatment. The results of the study showed that, a statistically significant difference was not seen between the effect of Darvyadi and Drakshadilehya in Pandu roga.