Academic literature on the topic 'Dheds'

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Journal articles on the topic "Dheds"

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Hammer, Fabian, Sandra Subtil, Philipp Lux, et al. "No Evidence for Hepatic Conversion of Dehydroepiandrosterone (DHEA) Sulfate to DHEA: In Vivo and in Vitro Studies." Journal of Clinical Endocrinology & Metabolism 90, no. 6 (2005): 3600–3605. http://dx.doi.org/10.1210/jc.2004-2386.

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Dehydroepiandrosterone (DHEA) sulfate (DHEAS) is the most abundant steroid in the human circulation and is thought to be the circulating hydrophilic storage form of DHEA. It is generally accepted that DHEA and DHEAS interconvert freely and continuously via hydroxysteroid sulfotransferases and steroid sulfatase and that only desulfated DHEA can be converted downstream to sex steroids. Here we analyzed DHEA/DHEAS interconversion in vivo and in vitro. We administered oral DHEA (100 mg) and iv DHEAS (25 mg) to eight healthy young men, resulting in similar increases in serum DHEAS compared with bas
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Prokai-Tatrai, Katalin, and Laszlo Prokai. "CNS-Selective Estrogen Therapy." Proceedings 22, no. 1 (2019): 31. http://dx.doi.org/10.3390/proceedings2019022031.

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17β-Estradiol (E2), the main human estrogen, has been known to exert multiple actions throughout the body, including in the central nervous system (CNS). In particular, it has been shown that E2 is gender-independently needed for brain and eye health. Lack of E2 due to normal aging and/or pathological processes leads to neurological and psychiatric diseases as well as accelerated neurodegeneration. Current estrogen replacement therapies, however, cannot be used as therapeutic interventions to treat these maladies due to a profound, unwanted hormonal exposure to the rest of the body. In this pr
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Takeshita, Rafaela S. C., Melissa K. Edler, Richard S. Meindl, Chet C. Sherwood, William D. Hopkins, and Mary Ann Raghanti. "Age, adrenal steroids, and cognitive functioning in captive chimpanzees (Pan troglodytes)." PeerJ 10 (November 9, 2022): e14323. http://dx.doi.org/10.7717/peerj.14323.

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Background Dehydroepiandrosterone-sulfate is the most abundant circulating androgen in humans and other catarrhines. It is involved in several biological functions, such as testosterone production, glucocorticoid antagonist actions, neurogenesis and neuroplasticty. Although the role of dehydroepiandrosterone-sulfate (DHEAS) in cognition remains elusive, the DHEAS/cortisol ratio has been positively associated with a slower cognitive age-decline and improved mood in humans. Whether this relationship is found in nonhuman primates remains unknown. Methods We measured DHEAS and cortisol levels in s
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Yasui, Saya, Yousuke Kaneko, Hiroki Yamagami, et al. "Dehydroepiandrosterone Sulfate, an Adrenal Androgen, Is Inversely Associated with Prevalence of Dynapenia in Male Individuals with Type 2 Diabetes." Metabolites 13, no. 11 (2023): 1129. http://dx.doi.org/10.3390/metabo13111129.

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Dehydroepiandrosterone sulfate (DHEAS) is thought to be associated with life expectancy and anti-aging. Although skeletal muscle disorders are often found in diabetic people, the clinical significance of DHEAS in skeletal muscle remains unclear. Therefore, we aimed to determine whether DHEAS is associated with the development of skeletal muscle disorders in individuals with type 2 diabetes (T2D). A cross-sectional study was conducted in 361 individuals with T2D. Serum DHEAS levels, skeletal muscle mass index (SMI), handgrip strength (HS), and gait speed (GS) were measured in the participants.
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Best, Hannah L., Sophie R. Cook, Helen Waller-Evans, and Emyr Lloyd-Evans. "Niemann-Pick C-like Endolysosomal Dysfunction in DHDDS Patient Cells, a Congenital Disorder of Glycosylation, Can Be Treated with Miglustat." International Journal of Molecular Sciences 26, no. 4 (2025): 1471. https://doi.org/10.3390/ijms26041471.

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DHDDS (dehydrodolichol diphosphate synthetase) and NgBR (Nogo-B Receptor) collectively form an enzymatic complex important for the synthesis of dolichol, a key component of protein N-glycosylation. Mutations in DHDDS and the gene encoding NgBR (NUS1) are associated with neurodevelopmental disorders that clinically present with epilepsy, motor impairments, and developmental delay. Previous work has demonstrated both DHDDS and NgBR can also interact with NPC2 (Niemann-Pick C (NPC) type 2), a protein which functions to traffic cholesterol out of the lysosome and, when mutated, can cause a lysosom
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Nunes-Souza, Emanuelle, Mônica Evelise Silveira, Monalisa Castilho Mendes, et al. "From adrenarche to aging of adrenal zona reticularis: precocious female adrenopause onset." Endocrine Connections 9, no. 12 (2020): 1212–20. http://dx.doi.org/10.1530/ec-20-0416.

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Objective Adaptive changes in DHEA and sulfated-DHEA (DHEAS) production from adrenal zona reticularis (ZR) have been observed in normal and pathological conditions. Here we used three different cohorts to assess timing differences in DHEAS blood level changes and characterize the relationship between early blood DHEAS reduction and cell number changes in women ZR. Materials and methods DHEAS plasma samples (n = 463) were analyzed in 166 healthy prepubertal girls before pubarche (<9 years) and 324 serum samples from 268 adult females (31.9–83.8 years) without conditions affecting steroidogen
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Lisnyansky Bar-El, Michal, Su Youn Lee, Ah Young Ki, et al. "Structural Characterization of Full-Length Human Dehydrodolichyl Diphosphate Synthase Using an Integrative Computational and Experimental Approach." Biomolecules 9, no. 11 (2019): 660. http://dx.doi.org/10.3390/biom9110660.

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Dehydrodolichyl diphosphate synthase (DHDDS) is the catalytic subunit of the heteromeric human cis-prenyltransferase complex, synthesizing the glycosyl carrier precursor for N-linked protein glycosylation. Consistent with the important role of N-glycosylation in protein biogenesis, DHDDS mutations result in human diseases. Importantly, DHDDS encompasses a C-terminal region, which does not converge with any known conserved domains. Therefore, despite the clinical importance of DHDDS, our understating of its structure–function relations remains poor. Here, we provide a structural model for the f
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Bonser, J., J. Walker, A. Purohit, et al. "Human granulosa cells are a site of sulphatase activity and are able to utilize dehydroepiandrosterone sulphate as a precursor for oestradiol production." Journal of Endocrinology 167, no. 3 (2000): 465–71. http://dx.doi.org/10.1677/joe.0.1670465.

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Dehydroepiandrosterone sulphate (DHEAS) is the most abundant androgen in the circulation and in ovarian follicular fluid. A steroid sulphatase accepting DHEAS as a substrate has been identified in the follicle, but the cellular location has not been determined. As DHEAS is also a potential source of oestrogen for endocrine-dependent tumours, a potent steroid sulphatase inhibitor oestrone-3-O-sulphamate (EMATE) has been developed which inhibits this activity in rat liver and mammary tumour. The aim of this study was to investigate human granulosa cells as a site of steroid sulphatase activity,
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Tóth, Miklós, Károly Rácz, Ibolya Varga, et al. "Plasma dehydroepiandrosterone sulfate levels in patients with hyperfunctioning and non-hyperfunctioning adrenal tumors before and after adrenal surgery." European Journal of Endocrinology 136, no. 3 (1997): 290–95. http://dx.doi.org/10.1530/eje.0.1360290.

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Abstract To investigate the clinical significance of plasma dehydroepiandrosterone sulfate (DHEAS) measurements, 175 patients with histologically confirmed adrenal tumors, 10 cortisol-producing adenomas, 59 aldosterone-producing adenomas, 56 non-hyperfunctioning adenomas, 13 adrenocortical carcinomas, 13 adrenal cysts, and 24 adrenomedullary tumors were studied. Plasma DHEAS levels were expressed as percentage of the mean of sex- and age-matched groups of healthy, normal subjects (DHEAS %). We found that before adrenal surgery, DHEAS % values were significantly reduced in patients with cortiso
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Marozkina, Nadzeya, Joe Zein, Mark D. DeBoer, et al. "Dehydroepiandrosterone Supplementation May Benefit Women with Asthma Who Have Low Androgen Levels: A Pilot Study." Pulmonary Therapy 5, no. 2 (2019): 213–20. http://dx.doi.org/10.1007/s41030-019-00101-9.

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ABSTRACT Introduction Among individuals with severe asthma, FEV1 is low in individuals with low dehydroepiandrosterone (DHEA) sulfate (DHEAS) levels. In the Severe Asthma Research Program (SARP), no women with DHEAS > 200 μg/dL had an FEV1 < 60% predicted. DHEA has benefited patients with COPD and pulmonary hypertension in small trials. Therefore, we hypothesized that DHEA supplementation may improve FEV1 in asthmatic women with low DHEAS. Methods Premenopausal, nonsmoking, otherwise healthy women, 18-50 years old, with mild or moderate asthma and baseline FEV1 > 60% predicted receive
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Dissertations / Theses on the topic "Dheds"

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Blombäck, Erik. "Samband mellan testosteron, DHEAS, kroppskomposition och fysiska kapaciteter hos unga kvinnliga fotbollsspelare." Thesis, Umeå universitet, Idrottsmedicin, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-76830.

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Testosterone is a steroid and anabolic hormone found in all mammals. Previous research indicates that testosterone levels correlates with physical capacities related to physical performance. However, these studies refers only to men and boys. The aim of present study was therefore to investigate the potential relationship between body composition, strength, power and endurance capabilities in relation to blood levels of testosterone and DHEAS in young female football players. Seventeen female elite football (age: 15,4 ± 0,6, body mass: 57,2 ± 7,4kg, height 1,65 ±0,04m) players volunteered for
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Nicolas, Laurent B. "La stéroïde sulfatase : localisation cérébrale et implication dans l'expression de certains comportements chez la souris adulte : interactions avec la DHEAS." Paris 6, 2003. http://www.theses.fr/2003PA066240.

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Schlereth, Florian [Verfasser], Bruno [Gutachter] Allolio, and Jörg [Gutachter] Wischhusen. "Expression of the DHEA/DHEAS-Shuttle in cell lines and foetal tissue of human liver, adrenal and cartilage / Florian Schlereth. Gutachter: Bruno Allolio ; Jörg Wischhusen." Würzburg : Universität Würzburg, 2014. http://d-nb.info/1102826944/34.

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L'Allemand-Jander, Dagmar. "Untersuchungen zur normalen und pathologischen Steuerung der Nebennierenrinden-Androgene im Kindesalter." Doctoral thesis, [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969645805.

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謝喜龍 та Hsi-Lung Hsieh. "以鼠腎髓腫瘤PC12細胞為材料探討DHEAS對多巴胺分泌之調節作用". 碩士, 東吳大學, 1985. http://ndltd.ncl.edu.tw/cgi-bin/gs32/gsweb.cgi/login?o=dnclcdr&s=id=%22085SCU03381001%22.&searchmode=basic.

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Thøgersen, Anna Margrethe. "Risk markers for a first myocardial infarction." Doctoral thesis, Umeå : Public Health and Clinical Medicine, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-603.

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Hsieh, Hsi-Lung, and 謝喜龍. "The Effects of DHEAS on Dopamine Secretion from PC12 Cells." Thesis, 1997. http://ndltd.ncl.edu.tw/handle/55060930824302689582.

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Köhler, Ines Luise. "DHEA-Substitutionstherapie bei gesunden älteren Männern mit niedrigem DHEAS-Serumspiegel." Doctoral thesis, 2003. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-7737.

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Dehydroepiandrosteron (DHEA) und sein Sulfatester Dehydroepiandrosteronsulfat (DHEAS) gehören zur Gruppe der adrenalen Androgene und sind wichtige Vorläufersubstanzen der Androgen- und Östrogensynthese beim Menschen. Die adrenale Androgensynthese beim Menschen weist einen Rückgang mit zunehmendem Alter auf. Damit stellt sich die Frage, ob niedrigere Serumspiegel von DHEA/S im Alter lediglich eine physiologische Veränderung darstellen oder Zusammenhänge zu pathologischen altersassoziierten Prozessen und Krankheiten bestehen. Um mögliche positive und protektive Eigenschaften von DHEA/S bei älter
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Liu, Yi-Chun, and 劉怡君. "Developmental genetic study of Drosophila homologue of Human enhancer of decapping large subunit, dHedls." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/93380950798728349703.

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碩士<br>國立臺灣大學<br>分子與細胞生物學研究所<br>96<br>Processing bodies (P-bodies) are specific cytoplasmic foci containing proteins involved in the 5’ to 3’ mRNA decay pathway. Some proteins involved in translational repression, mRNA quality control pathway and RNA-mediated gene silencing together with their mRNA targets are also localized to P-bodies. The components of P-bodies are highly conserved among yeast, human and Drosophila. In human cells, Hedls (Human enhancer of decapping large subunit) is a scaffold protein which interacts with human decapping protein 1 (hDcp1a) and human decapping protein 2 (hDc
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Liu, Yi-Chun. "Developmental genetic study of Drosophila homologue of Human enhancer of decapping large subunit, dHedls." 2008. http://www.cetd.com.tw/ec/thesisdetail.aspx?etdun=U0001-2507200812452400.

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Books on the topic "Dheds"

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Centre for Social Studies, Surat., ed. Religious conversion and social mobility: A case study of the Vankars in central Gujarat. Centre for Social Studies, 1991.

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Parmar, Y. A. The Mahyavanshi: The success story of a scheduled caste. Mittal Publications, 1987.

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Al-Nayhoum, Al-Sadek. Islam dheda al Islam. 3rd ed. Riad El-Rayyes, 2000.

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Pádraig, Ó. Fiannachta, and Foras na Gaeilge, eds. An mám ó dheas. An Sagart, 2009.

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The silken swing: The cultural universe of dalit women. Stree, 2000.

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Haley, Patty, and Rieko Woodford-Robinson. Saoire Dheas! M.H. Gill & Co. U. C., 2010.

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lÁMHACHÓIR IS FEARR Ó DHEAS ÓN BPHOL THUAIDH. Independently Published, 2020.

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Book chapters on the topic "Dheds"

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Zahid, Sarwar, Kari Branham, Dana Schlegel, et al. "DHDDS." In Retinal Dystrophy Gene Atlas. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-10867-4_27.

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Caffrey, Rebecca E., Zoher F. Kapasi, Stephen T. Haley, John G. Tew, and Andras K. Szakal. "Dheas Enhances Germinal Center Responses in Old Mice." In Advances in Experimental Medicine and Biology. Springer New York, 1994. http://dx.doi.org/10.1007/978-1-4615-2492-2_38.

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Beishuizen, A., and A. B. J. Groeneveld. "Dehydroepiandrosterone (DHEA) and its Sulfate (DHEAS) in Critical Illness." In Intensive Care Medicine. Springer New York, 2003. http://dx.doi.org/10.1007/978-1-4757-5548-0_82.

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Wen, Rong, Julia E. Dallman, Yiwen Li, et al. "Knock-Down DHDDS Expression Induces Photoreceptor Degeneration in Zebrafish." In Retinal Degenerative Diseases. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-3209-8_69.

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Lam, Byron L., Stephan L. Züchner, Julia Dallman, et al. "Mutation K42E in Dehydrodolichol Diphosphate Synthase (DHDDS) Causes Recessive Retinitis Pigmentosa." In Retinal Degenerative Diseases. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-3209-8_21.

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Dinesh, Arya, and V. R. Renjith. "Intuitionistic Fuzzy-Based ETA for Risk Assessment of DHDS Unit." In Advances in Behavioral Based Safety. Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-8270-4_5.

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Barrett-Connor, E., and K.-T. Khaw. "THE EPIDEMIOLOGY OF DHEAS WITH PARTICULAR REFERENCE TO CARDIOVASCULAR DISEASE: THE RANCHO BERNARDO STUDY." In The Biologic Role of Dehydroepiandrosterone (DHEA), edited by M. Kalimi and W. Regelson. De Gruyter, 1990. http://dx.doi.org/10.1515/9783110847383-018.

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Sasaki, Diane M., Ying Yuan, Katherine Gikas, et al. "Development of Enzyme Immunoassays for 5,6-, 8,9-,11,12-, And 14,15- Eets and the Corresponding Dhets." In Advances in Experimental Medicine and Biology. Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0193-0_81.

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Roberts, Eugene. "DEHYDROEPIANDROSTERONE (DHEA) AND ITS SULFATE (DHEAS) AS NEURAL FACILITATORS: EFFECTS ON BRAIN TISSUE IN CULTURE AND ON MEMORY IN YOUNG AND OLD MICE. A CYCLIC GMP HYPOTHESIS OF ACTION OF DHEA AND DHEAS IN NERVOUS SYSTEM AND OTHER TISSUES." In The Biologic Role of Dehydroepiandrosterone (DHEA), edited by M. Kalimi and W. Regelson. De Gruyter, 1990. http://dx.doi.org/10.1515/9783110847383-004.

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"DHEAS." In Springer Reference Medizin. Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_300483.

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Conference papers on the topic "Dheds"

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Mellbring, G., J. Chotai, and T. K. Nilsson. "PLASMA DEHYDROEPIANDROSTERONE SULPHATE CONCENTRATIONS AND DEEP VEIN THROMBOSIS AFTER MAJOR ABDOMINAL SURGERY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644208.

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Dehydroepiandrosterone sulphate (DHEAS) is a major secretory product of the human adrenal gland. Its precise functions are uncertain, but it has been postulated as a discriminator of life expectancy and aging. We have previously reported significantly lower plasma levels of DHEAS pre- and postoperatively in men developing DVT after major abdominal surgery, as compared to patients who remained free of DVT. Recent data suggest that the DHEAS concentration is also independently and inversely related to death from cardiovascular disease in men over 50 years of age. We here report data on preoperat
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Hesselink, Lambertus, John F. Heanue, Matthew C. Bashaw, A. J. Daiber, and R. Snyder. "Fundamental materials and device issues for digital holographic data storage." In Nonlinear Optics: Materials, Fundamentals and Applications. Optica Publishing Group, 1996. http://dx.doi.org/10.1364/nlo.1996.jtua.1.

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The performance of digital holographic data storage (DHDS) systems is primarily limited by the recording medium, as other components have been developed for consumer applications. In this invited paper we review state-of-the-art DHDS systems, fixing issues, and fundamental tradeoffs between materials and device characteristics. Recent results, including stored and retrieved video clips will be presented.
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Jethwani, Umesh, and Divya Jethwani. "Sertoli cell tumor of ovary: A rare case report." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685324.

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Introduction: Sertoli-Leydig cell tumor (SLCT) is a rare ovarian tumor, Constitute less than 0.5% of ovarian tumors. Most tumors are unilateral, confined to the ovaries. They are seen during the second and third decades of life. They are characterized by the presence of testicular structures that produce androgens. Patients have symptoms of virilization (depending on the quantity of androgen). Case Report: A 42-year-old woman presented Amenorrhea for 14 months. Change in her voice for 1 year and Excessive hair growth on her face, chest, and limbs for the last 2 months. She complained of vague
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