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Dissertations / Theses on the topic 'Diabetic Coronary Artery Disease'

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1

Nyström, Thomas. "On endothelial function in type 2 diabetic patients with coronary artery disease /." Stockholm : Karolinska institutet, 2005. http://diss.kib.ki.se/2005/91-7140-318-3/.

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2

Ridge, Charlotte. "Elemental concentrations in blood from diabetic and non-diabetic coronary artery bypass patients using neutron activation analysis and proton induced X-ray emission analyses." Thesis, University of Surrey, 2001. http://epubs.surrey.ac.uk/843100/.

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Diabetes is one of the fastest growing diseases today, affecting over a million people in the UK. Numerous medical complications, such as heart disease, are regularly associated with diabetes. Despite advances in methods of diagnosis and treatment there is still a need for greater understanding of these diseases. This will include research directed towards the influence of specific treatments and reasons for the high incidence of diabetes and heart disease in 'at risk' populations. Changes in elemental status are associated as the cause or effect of various diseased states. Elemental imbalance
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3

Jeevarethinam, Anand. "Cardiovascular risk stratification : relationship between carotid atherosclerosis and coronary artery disease in asymptomatic diabetes." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/1556370/.

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Background: Carotid intima-media thickness (CIMT) measurement and carotid plaque detection by B-mode carotid ultrasound (CUS) are frequently used as surrogates to predict coronary artery disease (CAD). However, they are not routine clinical practice in the asymptomatic diabetic population. Objectives: The aims of this study were 1) evaluate the relationship between carotid disease assessed by Carotid US and CAD assessed by computed tomography coronary angiography (CTCA), which also included a coronary calcium (CAC) scan; 2) identify carotid parameters to predict the severity and extent of coro
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4

Rossetti, L. "PLATELET ACTIVATION AND ASSOCIATED TRANSCRIPTIONAL SIGNATURE IN TYPE 2 DIABETIC PATIENTS WITH STABLE CORONARY ARTERY DISEASE: INSIGHTS INTO THEIR THROMBOTIC PROPENSITY." Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/246942.

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Platelet activation and associated transcriptional signature in type 2 diabetic patients with stable coronary artery disease: insights into their thrombotic propensity Several studies indicate that despite aspirin therapy patients with type-2 diabetes mellitus (T2DM) have both an enhanced platelet reactivity and a hypercoagulable state, supporting the evidence of a greater incidence of coronary artery disease (CAD) compared to patients without T2DM. Tissue Factor (TF) is the principal activator of blood coagulation; it is also expressed by platelets, which, upon activation translocate the p
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5

Szabó, Zoltán. "Diabetes and coronary surgery : metabolic and clinical studies on diabetic patients after coronary surgery with special reference to cardiac metabolism and high-dose GIK /." Linköping : Univ, 2001. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-5219.

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6

Hill, Brent J. F. "Myoplasmic calcium regulation and the function of nucleotide and endothelin receptors in models of coronary artery disease." free to MU campus, to others for purchase, 2000. http://wwwlib.umi.com/cr/mo/fullcit?p9988669.

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7

GARDE, SIDDHARTH ANANT. "Periodontal treatment for decreasing cardiovascular risk in patients with type 2 diabetes mellitus or coronary artery disease." Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/25583.

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Background: Periodontitis is a chronic inflammatory disorder of the tissues surrounding teeth and is a common cause of tooth loss. Chronic oral infections and the associated inflammatory response may also have negative ramifications on systemic diseases, including atherosclerotic cardiovascular disease (ACVD) and type 2 diabetes mellitus (T2DM). Multiple cross-sectional and longitudinal studies have indicated an increased risk of ACVD in individuals with periodontitis, independent of confounding factors. Aims: To provide an overview of periodontitis and its relationship with systemic disease
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8

Mamudu, Hadii M., Arsham Alamian, Timir Paul, et al. "Diabetes, Subclinical Atherosclerosis and Multiple Cardiovascular Risk Factors in Hard-to-Reach Asymptomatic Patients." Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/etsu-works/2778.

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Aim: To examine the association of cardiovascular disease risk factors with and their cumulative effect on coronary artery calcium in hard-to-reach asymptomatic patients with diabetes. Methods: : A total of 2563 community-dwelling asymptomatic subjects from Central Appalachia participated in coronary artery calcium screening at a heart centre. Binary variable was used to indicate that coronary artery calcium was either present or absent. Independent variables consisted of demographic and modifiable risk factors and medical conditions. Descriptive statistics and multinomial logistic regression
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9

Mediratta, Vikramaditya. "IMPLEMENTATION AND ASSESSMENT OF HYPERGLYCEMIC CONDITIONS FOR THE CREATION OF A DIABETIC BLOOD VESSEL MIMIC." DigitalCommons@CalPoly, 2011. https://digitalcommons.calpoly.edu/theses/591.

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Introduction: Diabetes Mellitus is a metabolic disorder that affects a person’s ability to either produce insulin (Type I diabetes mellitus) or properly use insulin (Type II diabetes mellitus) in order to maintain adequate blood glucose levels. The most severe diabetic complications arise due to hyperglycemia – a state of extremely high blood glucose levels – such as, coronary artery disease (CAD), in which coronary stent therapy is a popular method of treatment. However, research has shown a high rate of in-stent restenosis in diabetic patients with CAD, most likely due to activation of ce
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10

Tran, Hoang V. "Ventricular Arrhythmias Complicating Coronary Artery Disease: Recent Trends, Risk Associated with Serum Glucose Levels, and Psychological Impact." eScholarship@UMMS, 2018. https://escholarship.umassmed.edu/gsbs_diss/980.

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Introduction: Ventricular arrhythmias (VAs) are common after an acute coronary syndrome (ACS) and are associated with worse clinical outcomes. However, little is known about recent trends in their occurrence, their association with serum glucose levels, and their psychological impact in ACS setting. Methods: We examined 25-year (1986-2011) trends in the incidence rates (IRs) and hospital case-fatality rates (CFRs) of VAs, and the association between serum glucose levels and VAs in patients with an acute myocardial infarction (AMI) in the Worcester Heart Attack Study. Lastly, we examined the re
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11

Andreini, D. "PROGNOSTIC VALUE OF MULTIDETECTOR COMPUTED TOMOGRAPHY CORONARY ANGIOGRAPHY IN DIABETES: EXCELLENT LONG-TERM PROGNOSIS IN PATIENTS WITH NORMAL CORONARY ARTERIES." Doctoral thesis, Università degli Studi di Milano, 2013. http://hdl.handle.net/2434/219084.

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Objective: To assess the prognostic role of multidetector computed tomography coronary angiography (MDCT-CA) in diabetics with suspected coronary artery disease (CAD). Use of MDCT-CA is increasing in patients with suspected CAD. However, data supporting its prognostic value in diabetics are limited. Research Design and Methods: Between January 2006 and September 2007, 429 consecutive diabetic patients were prospectively studied with MDCT-CA for detecting presence and assessing extent of CAD (disease extension and coronary plaque scores). Patients were classified according to the presence of n
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12

Karjalainen, J. (Jaana). "Cardiovascular autonomic function in coronary artery disease patients with and without type 2 diabetes:significance of physical activity and exercise capacity." Doctoral thesis, Oulun yliopisto, 2013. http://urn.fi/urn:isbn:9789526202723.

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Abstract Coronary artery disease (CAD) and type 2 diabetes (T2D) are associated with cardiovascular autonomic dysfunction, which is widely used as a predictor of mortality in cardiovascular diseases. The determinants of autonomic dysfunction in CAD patients with or without T2D are not well known. The aim of this thesis was to examine the determinants of cardiovascular autonomic function in healthy subjects and CAD patients with and without T2D. A second aim was to study the prognostic value of autonomic function in the patient population. A third aim was to study the effects of exercise prescr
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13

Capodanno, Davide Francesco Maria. "Effetti farmacodimanici di differenti regimi di somministrazione dell'aspirina in pazienti con diabete mellito di tipo II e cardiopatia ischemica." Doctoral thesis, Università di Catania, 2012. http://hdl.handle.net/10761/1090.

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I pazienti con diabete mellito di tipo II presentano ridotti effetti farmacodinamici piastrinici indotti dall'aspirina. Ciò potrebbe dipendere dal loro aumentato turnover piastrinico, che potrebbe a sua volta escludere una proporzione delle piastrine circolanti da una adeguata esposizione all'azione dell'aspirina. L'ipotesi di questo studio è che in pazienti con diabete mellito di tipo II e cardiopatia ischemica un incremento della frequenza di somministrazione dell'aspirina determina una maggiore inibizione piastrinica rispetto ad un aumento della dose.
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14

Nxumalo, Mikateko. "The association of methylglyoxal-adducts with kinetics and ultrastructure of fibrin clots in coronary artery disease patients with type 2 diabetes mellitus." Diss., University of Pretoria, 2020. http://hdl.handle.net/2263/79097.

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Background: Glycation influences the ultrastructure and clot kinetics of fibrin clots due to the post-translational modifications in fibrinogen. Methylglyoxal (MG) is used to measure the level of glycation which has been associated with the pathogenesis of type 2 diabetes Melilites (T2DM) and coronary heart disease (CHD). The aim of the study was to determine the role of MG on clot kinetics and fibrin clot structure in CHD patients with and without T2DM to provide insight into the mechanism of pathogenesis of atherosclerosis in T2DM which results in the development of CHD. Methodology:
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15

Snell-Bergeon, Janet K. "Reproductive history and sex hormones and their association with subclinical atherosclerosis in women with and without type 1 diabetes /." Connect to full text via ProQuest. Limited to UCD Anschutz Medical Campus, 2007.

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Thesis (Ph.D. in Epidemiology) -- University of Colorado Denver, 2007.<br>Typescript. Includes bibliographical references (leaves 100-117). Free to UCD affiliates. Online version available via ProQuest Digital Dissertations;
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16

Timóteo, Ana Teresa de Matos. "Caracterização da aterosclerose sub-clínica e doença coronária em doentes com síndrome metabólica e diabetes mellitus." Doctoral thesis, Faculdade de Ciências Médicas. UNL, 2013. http://hdl.handle.net/10362/10304.

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RESUMO- Introdução: A obesidade e a Síndrome Metabólica (SM) são atualmente um importante problema de saúde pública, com prevalências crescentes, que se acompanham também por aumento da prevalência de Diabetes Mellitus (DM).Estudos prévios demonstram associação destas entidades com o aumento de risco de eventos cardiovasculares, em particular a DM. A SM tem sido uma entidade muito debatida nos últimos anos, com aparecimento de diversas definições, contribuindo para resultados díspares no que diz respeito à influência da SM nas doenças cardiovasculares. Também têm sido descritas variações étnic
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17

Fitt, Jacqueline S. "Is the endothelial nitric oxide synthase (eNOS) gene a susceptibility gene for coronary artery disease, hypertension and type 2 diabetes among North Indian populations?" Thesis, Loughborough University, 2011. https://dspace.lboro.ac.uk/2134/9913.

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Coronary artery disease (CAD), Hypertension (Ht) and Type 2 Diabetes Mellitus (T2DM) are all global health problems. This is particularly evident amongst South Asian population groups. The conventional risk factors do not fully explain the higher prevalence of these diseases among South Asians. The endothelial Nitric Oxide Synthase (eNOS) gene is responsible for the production of Nitric Oxide (NO), which may contribute to the physiology of all three disease states. Endothelial dysfunction (which is characterised by a reduction in basal NO) has been shown to be present in, or prior to all three
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18

Hibbert, Benjamin. "Glycogen Synthase Kinase 3 Beta Inhibition for Improved Endothelial Progenitor Cell Mediated Arterial Repair." Thesis, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/24348.

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Increasingly, cell-based therapy with autologous progenitor populations, such as endothelial progenitor cells (EPC), are being utilized for treatment of vascular diseases. However, both the number and functional capacity are diminished when cells are derived from patients with established risk factors for coronary artery disease (CAD). Herein, we report that inhibition of glycogen synthase kinase 3 (GSK) can improve both the number and function of endothelial progenitor cells in patients with CAD or diabetes mellitus (DM) leading to greater therapeutic benefit. Specifically, use of various sm
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19

Karathanos, Athanasios [Verfasser], and Tobias [Akademischer Betreuer] Geisler. "Macrophage migration inhibitory factor and gremlin-1 in patients with coronary artery disease and diabetes : patterns of expression and interaction / Athanasios Karathanos ; Betreuer: Tobias Geisler." Tübingen : Universitätsbibliothek Tübingen, 2018. http://d-nb.info/1196701288/34.

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20

Viswanathan, Girish. "Evaluation of platelet dependent thrombosis and the role of dual antiplatelet therapy on blood thrombogenicity in patients with type 2 diabetes mellitus and coronary artery disease." Thesis, University of Newcastle upon Tyne, 2014. http://hdl.handle.net/10443/2603.

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Evaluation of platelet dependent thrombosis and the role of dual antiplatelet therapy on blood thrombogenicity in patients with type 2 diabetes mellitus and coronary artery disease The prevalence of type 2 diabetes mellitus (T2DM) is rapidly increasing. Recurrent thrombotic events and cardiac mortality are higher in T2DM. Aims: My overall aim was to identify abnormalities in blood thrombogenicity in T2DM and assess the response to dual antiplatelet therapy. Hypotheses: Study 1 ACS study: Patients with T2DM have increased blood thrombogenicity following non ST-elevation acute coronary syndromes
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21

Жаркова, Альбiна Володимирiвна, Г. В. Логвинюк, Альбина Владимировна Жаркова та Albina Volodymyrivna Zharkova. "Оцінка впливу поєднання ішемічної хвороби серця та цукрового діабету 2 типу на характеристики інтервалу QT". Thesis, Сумський державний університет, 2014. http://essuir.sumdu.edu.ua/handle/123456789/35641.

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Ішемічна хвороба серця (ІХС) є одним з найбільш розповсюджених патологічних станів, що призводить до погіршення якості життя, інвалідизації та смертності населення. Значно погіршує клінічний перебіг і посилює ризик розвитку судинних ускладнень наявність супутньої патології – цукрового діабету (ЦД) 2 типу. Насьогодні значна увага приділяється прогностичному значенню тривалості та дисперсії інтервалу QT як маркера розвитку фатальних аритмій і раптової коронарної смерті у хворих на ІХС у поєднанні з ЦД 2 типу. Стани гіперглікемії і гіпоглікемії при ЦД можуть призводити до подовження інтервалу QT,
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22

Орловський, Віктор Феліксович, Виктор Феликсович Орловский, Viktor Feliksovych Orlovskyi та О. І. Опімах. "Особливості сумісного перебігу ішемічної хвороби серця, гіпертонічної хвороби та цукрового діабету у хворих на етапі санаторно-курортного лікування". Thesis, Видавництво СумДУ, 2008. http://essuir.sumdu.edu.ua/handle/123456789/4647.

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23

Triches, Cristina Bergmann. "Doença macrovascular em pacientes com diabetes melito tipo 2 : aspectos do manejo clínico e avaliação de angina pectoris como fator de risco para eventos cardíacos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2010. http://hdl.handle.net/10183/27751.

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O diabetes melito (DM) é um fator de risco independente para doença arterial coronariana, acidente vascular cerebral, doença vascular periférica e insuficiência cardíaca, que são as principais causas de morte nesses pacientes. Além disso, pacientes com DM e doença cardiovascular têm pior prognóstico, por apresentarem menor sobrevida, maior risco de recorrência da doença e pior resposta aos tratamentos propostos. Os avanços diagnósticos e terapêuticos das últimas décadas já mostram uma redução do risco de eventos cardiovasculares nesses pacientes, mas o risco absoluto dos mesmos é ainda duas ve
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24

Tavoni, Thauany Martins. "Metabolismo e função das lipoproteínas de alta densidade (HDL) em indivíduos idosos: efeito da presença de diabetes mellitustipo 2 e doença coronária obstrutiva." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-08032019-181032/.

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Introdução: A doença arterial coronária (DAC) decorrente da aterosclerose é uma das principais causas de comprometimento do envelhecimento saudável e sobrevida do idoso.Entre os principais fatores de risco da DAC estão o diabetes mellitus tipo 2 (DM) e as dislipidemias. O HDL-colesterol baixo é fator de risco importante, mas aspectos funcionais e metabólicos da HDL devem ser avaliados, já que esta lipoproteína tem várias ações anti-aterogênicas. Neste sentido, a transferência de lípides de outras lipoproteínas para a HDL, mediada pela proteína de transferência de ésteres de colesterol (CETP),
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25

Holt, Jim, and Gregg Mitchell. "Coronary Artery Disease KSA." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etsu-works/6457.

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26

Bouillet, Benjamin. "Etude de la capacité d'inhibition de l'apolipoprotéine C1 sur l'activité de la protéine de transfert des esters de cholestérol chez des patients coronariens normolipidémiques et hyperlipidémiques et chez des patients diabétiques." Thesis, Dijon, 2013. http://www.theses.fr/2013DIJOS087/document.

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Une augmentation de l’activité de la protéine de transfert des esters de cholestérol (CETP) est retrouvée associée à une élévation du développement de l’athérosclérose. L’apolipoprotéine C1 est l’inhibiteur physiologique de la CETP. Ses propriétés électrostatiques jouent un rôle important dans sa capacité d’inhibition de l’activité CETP. Aucune étude de ce potentiel inhibiteur de l’apoC1 n’a été réalisée chez des patients à haut risque cardio-vasculaire ou dyslipidémiques. Nous avons souhaité étudier la fonctionnalité de l’apoC1 par rapport à la CETP chez des patients coronariens normolipidémi
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27

Morais, Natanael Vilela. "Estudo da perfusão miocárdica e reserva coronariana pela ecocardiografia sob estresse com perfusão em tempo real em pacientes com diabetes melito descompensado e após tratamento." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/5/5131/tde-03092010-122657/.

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Introdução: O diabetes melito (DM) está associado com alterações na reserva de fluxo coronariano a nível microcirculatório e a ecocardiografia sob estresse com perfusão em tempo real (EPMTR) é uma técnica útil para avaliação não invasiva dessas alterações. O objetivo deste estudo foi avaliar se o controle do DM teria influência sobre os valores da Reserva de Fluxo Microvascular (RFM) em pacientes livres de coronariopatia obstrutiva. Métodos: Estudamos 30 pacientes com DM tipo 2 (GD) e 11 pacientes saudáveis do grupo controle (GC). A RFM foi avaliada pela EPMTR utilizando contraste a base de mi
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Sprandel, Marilia da Costa Oliveira. "Efeito do metabolismo e função das lipoproteínas de alta densidade (HDL) em pacientes diabéticos tipo 2 com e sem doença coronária obstrutiva." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/5/5131/tde-26022014-095038/.

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Introdução:O diabetes mellitus tipo 2 (DM2) está associado ao aumento da mortalidade por doença arterial coronária (DAC). O DM2 afeta o metabolismo de lípides, levando à dislipidemia, caracterizada por hipertrigliceridemia e baixa concentração plasmática de HDL-colesterol. Transferências de lípides entre HDL e outras lipoproteínas são passos cruciais no metabolismo e função da HDL. Objetivo: Investigar se o desenvolvimento de DAC em pacientes com DM2 está associado com alterações na transferência de lípides para HDL. Métodos: Foram estudados 79 pacientes com DM2 portadores de DAC obstrutiva (D
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Mauro, Maria Fernanda Zuliani. "Análise volumétrica da hiperplasia intimal intra-stent farmacológico em pacientes diabéticos tratados com ou sem cilostazol." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/98/98131/tde-04102013-090756/.

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Fundamentos: Ensaios prévios reunindo pacientes em series consecutivas ou randomicas sem cegamento evidenciaram beneficio da adição do cilostozol à terapia antiplaquetária em diabéticos submetidos ao implante de stents coronários farmacológicos com redução nas taxas de reestenose binária, perda tardia intra-stent e revascularização tardia da lesão alvo. Objetivos: O objetivo primário deste estudo foi verificar se a adição do cilostazol à dupla terapia antiplaquetária, proporcionaria uma redução adicional da hiperplasia intimal em diabéticos após o implante de stent farmacológico, mensurada por
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Stancell-Smith, Gwendolyn Yvonne. "Women and Coronary Artery Disease." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/3415.

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Heart disease, including coronary artery disease, affects approximately 42 million women in the United States. Many of those affected are not aware they have the condition. Contributing to the problem is the fact that women are more likely than men to be misdiagnosed and undertreated for heart disease. Morbidity and mortality are high in women affected by heart disease, making the problem important to address. The purpose of this project was to understand the coronary artery or heart disease risk and the treatment for the condition provided for 31 participants at a cardiology service in the No
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31

Starkhammar, Johansson Carin. "Periodontitis and coronary artery disease : Studies on the association between periodontitis and coronary artery disease." Doctoral thesis, Linköpings universitet, Kardiologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-86213.

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Periodontitis and coronary artery disease (CAD) are highly prevalent in Sweden’s population; both diseases have complicated pathogeneses and clinical manifestations due to immune-system triggered inflammation. Research in recent years reported that inflammation is a significant active participant in many chronic diseases. The literature described a CAD-periodontitis association, but underlying mechanisms are not fully understood. It is important to acquire knowledge about how periodontitis might influence CAD, which is one of the major causes of illness and death in western countries. Because
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Sousa, André Gustavo Pires de. "Associação entre TCF7L2 e outras variantes genéticas de risco para Diabetes Mellitus Tipo 2 e doença cardiovascular." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/5/5131/tde-18022011-161431/.

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Introdução: Estudos prévios têm confirmado genes de susceptibilidade para Diabetes Mellitus tipo 2 em diferentes populações. Nesse contexto, os polimorfismos do gene TCF7L2 são considerados as mais importantes variantes genéticas de risco para o diabetes tipo 2, que, por sua vez, é um dos principais fatores de risco cardiovascular conhecidos, especialmente para doença arterial coronariana. Contudo, a hipótese de que variantes de risco do TCF7L2 ou a informação combinada de marcadores genéticos associados ao diabetes também podem predizer eventos cardiovasculares ainda não foi testada. Objetivo
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Ahmed, Nabeel. "Platelet reactivity in coronary artery disease." Thesis, Imperial College London, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.530480.

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34

Lee, Chi-hang, and 李志恆. "Microvascular obstruction following percutaneous coronary interventionfor coronary artery disease." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43278723.

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35

Ferrarezi, Daniela Andraus de Figueiredo. "Variações alélicas no gene do receptor da vitamina D (VDR) e risco de doença arterial coronariana em pacientes diabéticos tipo 2." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/5/5135/tde-05052011-142938/.

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A doença cardiovascular (DCV) é a principal causa de mortalidade e morbidade em pacientes portadores de diabetes mellitus tipo 2 (DM 2), estando associada com mais de 80% das mortes nesses pacientes. Portadores de DM 2 têm um risco três vezes maior em relação à indivíduos não diabéticos de desenvolver aterosclerose e suas complicações clínicas como infarto agudo do miocárdio (IAM), acidente vascular cerebral (AVC) e doença vascular periférica. O sistema endócrino da vitamina D regula a diferenciação e a proliferação de vários tipos celulares, além de possuir propriedades antiinflamatórias e an
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Lee, Chi-hang. "Microvascular obstruction following percutaneous coronary intervention for coronary artery disease." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43278723.

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37

Vollmer, Sandra Jeanne. "Diagonal earlobe creases and coronary artery disease." FIU Digital Commons, 1996. http://digitalcommons.fiu.edu/etd/3066.

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PURPOSE: The purpose of this study was to examine the relationship between the diagonal earlobe crease and the incidence of coronary artery disease. PATIENTS AND METHODS: A descriptive, correlational, retrospective and concurrent approach was utilized in examining 61 patients, all with a cardiac catheterization within the last six months. All were examined for the presence of diagonal earlobe crease, presence of coronary artery disease, total blood cholesterol levels, age, sex, and past medical histories. Analyses included the Fischer's exact test, regression analysis, and multiple logistic re
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38

Korte, Philippus Jacobus de. "Probability analysis in diagnosing coronary artery disease." Maastricht : Maastricht : Universitaire Pers Maastricht ; University Library, Maastricht University [Host], 1993. http://arno.unimaas.nl/show.cgi?fid=5861.

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39

Schulz, Katharine I. "Coping strategies in coronary artery disease patients." Virtual Press, 1993. http://liblink.bsu.edu/uhtbin/catkey/862273.

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40

Williams, Simon Robert Pask. "The physique associated with coronary artery disease." Thesis, Open University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250507.

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41

Roberts, Robert. "A genetic basis for coronary artery disease." Elsevier, 2015. http://hdl.handle.net/10150/623296.

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CAD and cancer account for over one-half of all deaths in the world. It is claimed that the 21st century is the last century for CAD. This is, in part, because CAD is preventable based on randomized, placebo-controlled clinical trials, which show modifying known risk factors such as cholesterol is associated consistently with 40–60% reduction in morbidity and mortality from CAD. Comprehensive prevention will require modifying genetic risk factors that are claimed to account for 40–60% of predisposition to CAD. The 21st century is meeting this challenge with over 50 genetic risk variants discov
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42

Mackenzie, Alison Jill. "Conduit artery structure and function in patients with coronary artery disease." Thesis, University of Glasgow, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.402008.

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43

Jensen, Jens. "On-line vectorcardiography during coronary angioplasty and unstable coronary artery disease /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4357-5/.

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44

Nijm, Johnny. "Inflammation and cortisol response i coronary artery disease." Doctoral thesis, Linköpings universitet, Institutionen för medicin och hälsa, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-15978.

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Atherosclerosis is characterized by a chronic inflammation, involving autoimmune components, in the arterial wall. An increase in proinflammatory activity relative to anti-inflammatory activity is considered to cause a progression of the disease towards plaque instability and risk of atherothrombotic events, such as acute coronary syndrome (ACS). Cortisol, the end product of the hypothalamus-pituitary-adrenal (HPA) axis, is a powerful endogenous anti-inflammatory mediator. Disturbances in the HPA axis have been reported in chronic inflammatory/autoimmune diseases, like rheumatoid arthritis. Th
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45

Gorog, Diana Adrienne. "Influences on platelet function in coronary artery disease." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272333.

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46

Shaw, James A. (James Alexander) 1968. "Mechanisms of plaque stability in coronary artery disease." Monash University, Dept. of Medicine, 2001. http://arrow.monash.edu.au/hdl/1959.1/9016.

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47

Söderman, Eva. "Depression, coronary artery disease and change of lifestyle /." Stockholm : [Karolinska institutets bibl.], 2001. http://diss.kib.ki.se/2001/91-7349-089-x/.

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48

Nijm, Johnny. "Inflammation and cortisol response in coronary artery disease /." Linköping : Univ, 2007. http://www.bibl.liu.se/liupubl/disp/disp2007/med1037s.pdf.

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49

Closa-León, Trinidad. "Social support, cardiovascular reactivity, and coronary artery disease." Thesis, University of Birmingham, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433738.

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50

Roberts, Will. "Assessment of coronary artery disease by computed tomography." Thesis, Queen Mary, University of London, 2013. http://qmro.qmul.ac.uk/xmlui/handle/123456789/8708.

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Computed Tomography Coronary Angiography (CTCA)is a technique for imaging coronary arteries with increasing indications in clinical cardiology. AIMS 1.Develop a heart rate (HR) lowering regime for CTCA and to measure its association with image quality. 2.Examine the diagnostic accuracy of 64 slice CTCA (CTCA64) in patients with known coronary artery disease (CAD). 3.Examine the diagnostic accuracy of CTCA64 for assessment of stent restenosis 4.Demonstrate utility of CTCA as an endpoint in assessment of novel diagnostic biomarkers of CAD. METHODS I developed a HR reducing strategy using metopro
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