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1

Noor, Shahnaz, Irum Noor, and Sadia Bashir. "Evaluation of Frequency of Diabetic Ketoacidosis and Presenting Symptoms in Patients of Diabetes Mellitus Presenting." Pakistan Journal of Medical and Health Sciences 15, no. 12 (2021): 3390–92. http://dx.doi.org/10.53350/pjmhs2115123390.

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Objective: To evaluate the frequency of diabetic ketoacidosis and presenting symptoms in patients of diabetes mellitus presenting at tertiary care hospital. Material and methods: In this cross sectional study total 145 patients of diabetes were selected from Department of Medicine from April 2020 to November 2020. Inclusion criteria was: un-controlled type II Diabetes Mellitus with HBA1c levels > 8, age between 30-70 years, male or female. Diabetic ketoacidosis was studied in selected patients. Results: Mean age of the patients 49.80 ± 9.38 years. Out of 145 patients, ketoacidosis was found
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2

Anchikov, L. I. "Emergency care for coma in diabetic patients." Kazan medical journal 76, no. 2 (1995): 149–52. http://dx.doi.org/10.17816/kazmj97154.

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In diabetes mellitus, acute complications are possible in the form of diabetic ketoacidosis, hyperosmolar, non-ketotic, non-acidotic states of hypoglycemia, which can cause coma if patients are not provided with timely assistance. Treatment of patients with ketoacidotic coma, which is more common than other complications, includes the administration of rapid-acting insulin, fluid replacement, gastric drainage, electrolyte replacement, and management of comorbidities. With ketoacidosis, table number 9 is shown with fat restriction; once a day, sweet tea is allowed until the disappearance of ace
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3

Sayyad, Naemoddin, and Samad Nazma. "Scientific evaluation of recurrent ketoacidosis in Diabetic mellitus patients." International Journal of Advanced Biotechnology and Research 12, no. 3 (2021): 9–13. https://doi.org/10.5281/zenodo.5635619.

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<strong>ABSTRACT&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </strong> The research was focused on To evaluate the diabetic ketoacidosis in cases of diabetes mellitus. Total 176 diabetic patients presenting at Department of Medicine, India from June 2019 to Dec 2019,both male or female with age range from 35-60 years were selected
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4

Tilinca, Mariana Cornelia, Csilla Nania, Sandor Pal, Raluca Tilinca, Monika Szabo, and Eniko Nemes-Nagy. "Evaluation of Metabolic and Hydroelectrolytic Disturbances in Patients Diagnosed with Diabetic Ketoacidosis." Revista de Chimie 71, no. 1 (2020): 239–43. http://dx.doi.org/10.37358/rc.20.1.7839.

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Ketoacidosis is a life-threatening complication of diabetes mellitus, especially type 1 diabetic patients being predisposed to this condition. Ketoacidosis might occur also in other types of diabetes triggered by circumstances leading to shortage of insulin. The aim of the study was the assessment of metabolic, hydroelectrolytic disturbances and the relationship between different parameters in patients hospitalized with diabetic ketoacidosis. We evaluated the clinical state, parameters of blood-gas analyzer, biochemistry and hematology laboratory results of 32 patients admitted with diabetic k
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5

HUSAIN, SYED SHAJEE, MUHAMMAD RIZWAN JAVED, and SARA AHMAD ALI. "DIABETIC KETOACIDOSIS." Professional Medical Journal 18, no. 01 (2011): 80–82. http://dx.doi.org/10.29309/tpmj/2011.18.01.1863.

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Objective: To determine the frequency of various precipitating factors for Diabetic Ketoacidosis (DKA) in patients with type 2 diabetes mellitus. Study Design, Setting &amp; Duration: This was a prospective study carried out at Department of Medicine, Muhammad Medical College &amp; Hospital Mirpurkhas, from February 2007 to February 2009. Patients &amp; Methods: 100 patients with type 2 diabetes mellitus admitted with diabetic ketoacidosis (DKA) were analyzed to determine the precipitating factors. Results: Out of 100 patients 47 were males and their average age was 47 years (range=17-65) whil
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6

Gavidia Quezada, Rocio, and Hawa Edriss. "Diabetic ketoacidosis: Should current management include subcutaneous insulin injections?" Southwest Respiratory and Critical Care Chronicles 5, no. 19 (2017): 6. http://dx.doi.org/10.12746/swrccc.v5i19.389.

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Diabetic ketoacidosis is a well-known acute complication in patients with both type 1 andtype 2 diabetes mellitus. Although mortality has decreased considerably, it remains an importantcause for admission to intensive care units. Medical management includes intravenous fluidtherapy, insulin, correction of electrolyte abnormalities, and addressing the precipitating factorwhich in most cases is infection or non-compliance with insulin therapy. Usually patients withdiabetic ketoacidosis are admitted to the intensive care unit for continuous infusion of insulin;however, the development of rapid ac
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7

Park, C. "Diabetic ketoacidosis." Journal of the Royal College of Physicians of Edinburgh 37, no. 1 (2007): 40–43. https://doi.org/10.1177/1478271520073701012.

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Diabetic ketoacidosis remains the most important acute complication of diabetes mellitus, causing metabolic decompensation with an associated morbidity and mortality of 1–10%. Although levels of morbidity and mortality are falling with modern management protocols, a significant threat still remains. While DKA is most common in patients with type 1 diabetes mellitus, it should not be overlooked in patients with type 2 diabetes mellitus, especially in those who require insulin. In contrast to chronic management, acute complications often present to Acute Medicine rather than to specialist diabet
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8

Thakare, Pratiksha Suresh, and Ruchira Ankar. "To Assess the Knowledge Regarding Signs and Symptoms of Diabetic Ketoacidosis and Its Prevention among Diabetes Patients in Wardha District, Maharashtra, India." Journal of Evolution of Medical and Dental Sciences 10, no. 19 (2021): 1413–16. http://dx.doi.org/10.14260/jemds/2021/298.

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BACKGROUND Diabetic ketoacidosis (DKA) is a life-threatening condition of diabetes that is characterized by hyperglycaemia, ketoacidosis, and ketonuria. It happens when glucose's ability to enter cells for use as metabolic fuel is blocked by absolute or relative insulin deficiency. This causes liver to divide fat into ketones as a source of fuel. The purpose of the study was to assess the knowledge regarding prevention of signs and symptoms of diabetic ketoacidosis among diabetes patients in selected hospitals of Wardha district. METHODS A descriptive study was undertaken among 60 purposively
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9

Dr., Maria Anwar Dr. Saadia Sehrish Dr. Moin Ata. "CORRELATION BETWEEN THE OUTCOMES AND SEVERITY OF DIABETIC KETOACIDOSIS: A RETROSPECTIVE PILOT STUDY." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 10 (2018): 10533–38. https://doi.org/10.5281/zenodo.1468965.

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<em>(DKA) Diabetic Ketoacidosis is a critical acute metabolic snag of DM (diabetes mellitus). Further, it is categorized into minor, moderate and severe grounded on sternness according to the guidelines of ADA (American Diabetes Association). There are limited literature and data based on the correlation between the outcomes of DKA while using this categorization system and the severity of Diabetic Ketoacidosis. The core objective of this study is to describe the correlation between severity of DKA and outcomes in a tertiary care center of India, and data has been extracted through Medline Dat
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10

Bratton, Susan L., and Elliot J. Krane. "Diabetic Ketoacidosis: Pathophysiology, Management and Complications." Journal of Intensive Care Medicine 7, no. 4 (1992): 199–211. http://dx.doi.org/10.1177/088506669200700407.

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Diabetic ketoacidosis (DKA) is a common and potentially life-threatening complication of diabetes mellitus, the second most common chronic childhood disease [1]. Prior to the introduction of insulin to clinical medicine by Banting and Best in 1922, DKA had a mortality rate greater than 60% [2]. As insulin was introduced into clinical practice, there was a gradual decrease in mortality associated with DKA over the subsequent 30 years. Recent epidemiological data reveal current mortality varies from 0 to 19% [3,4]. DKA continues to be the most common cause of death in patients younger than 24 ye
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11

Kansakar, Prerana, Shrijana Shrestha, Buddhi Prasad Paudyal, Alisha Prajapati, and Narottam Shrestha. "Risk Factors Associated with Diabetic Ketoacidosis at the Onset of Type 1 Diabetes Mellitus." Journal of Nepal Health Research Council 20, no. 01 (2022): 79–83. http://dx.doi.org/10.33314/jnhrc.v20i01.3841.

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Background: There are various factors which increase the risk of diabetic ketoacidosis at the onset of type 1 diabetes mellitus. There have not been any such studies in our setting. This study was done to find the prevalence and risk factors associated with the development of diabetic ketoacidosis at onset of type 1 diabetes mellitus. Methods: Children and young adults with type 1 diabetes mellitus being treated at Patan hospital were approached and after obtaining an informed consent, all the patient information on various risk factors for diabetic ketoacidosis were collected in a pre-develop
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12

Hassan Khan, Muhammad Imran, Junaid Mushtaq, Ibtesaam Amjad, Israr ul Haque Toor, and Ghias un Nabi Tayyab. "DIABETIC KETOACIDOSIS;." Professional Medical Journal 25, no. 08 (2018): 1235–39. http://dx.doi.org/10.29309/tpmj/2018.25.08.86.

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Objectives: To observe the frequency, precipitating factors and outcome ofdiabetic ketoacidosis (DKA) in adults with established and newly diagnosed type 1 diabetesat a tertiary care hospital. Study Design: Retrospective study. Setting: Lahore GeneralHospital, Lahore. Period: From January 2013 through December 2015. Methods: Patients whowere admitted with a diagnosis of DKA. The clinical presentations, laboratory investigations,management, time of recovery and outcome were compared. Data were collected viaretrospective chart review. Results: A total of 202 patients were included who fulfilled
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13

Nezhinskaya-Astapenko, Z. P., T. V. Sekret, and M. V. Vlasenko. "PREVALENCE OF DIABETIC KETOACIDOSIS AND ITS ETIOLOGICAL FACTORS IN THE PODILLYA REGION OF UKRAINE." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 18, no. 4 (2018): 33–40. http://dx.doi.org/10.31718/2077-1096.18.4.33.

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The diabetes mellitus is one of the most common diseases of the world. It is characterized by a large number of complications, including ketoacidosis and its severe form known as ketoacidosis diabetic coma. The aim was to estimate the causes of the development of diabetic ketoacidosis and the duration of treatment of an acute state in different age groups. Materials and methods. The random sampling of patients included 55 individuals with diabetes mellitus admitted to intensive care unit of the Vinnytsia Regional Highly Specialized Endocrinological Center aged from 9 up to 70 years in an emerg
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14

Serlina, Dela. "Diabetic Ketoasidosis." KESANS : International Journal of Health and Science 1, no. 3 (2021): 211–20. http://dx.doi.org/10.54543/kesans.v1i3.19.

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Diabetic ketoacidosis (DKA) is one of the acute complications for diabetics that usually occurs in type 1 DM, but it is possible in type 2 DM. DKA is caused by a decrease in effective insulin circulation associated with an increase in counter-regulatory hormones. The incidence of DKA ranges from 0 to 56 per 1000 people each year. In Indonesia, it is known that 71% of pediatric patients have DKA as the initial clinical presentation of type-1 DM in 2017. To know more about diabetic ketoacidosis. Knowing the characteristics of patients with diabetic ketoacidosis. Know how to treat patients with d
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15

Szypowska, Agnieszka, Anna Ramotowska, Monika Grzechnik-Gryziak, Wojciech Szypowski, Anna Pasierb, and Katarzyna Piechowiak. "High Frequency of Diabetic Ketoacidosis in Children with Newly Diagnosed Type 1 Diabetes." Journal of Diabetes Research 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/9582793.

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Aim. The aim of this study was to evaluate the incidence of diabetic ketoacidosis in children and adolescents with newly diagnosed type 1 diabetes in 2006-2007 and 2013-2014.Method. The study group consisted of 426 children aged 0–18 years with type 1 diabetes onset admitted to our hospital in 2006-2007 (group A) and 2013-2014 (group B). The study comprised the analysis of medical and laboratory records from patients’ medical charts and the electronic database.Results. There was no difference between groups A and B in the percentage of children admitted with diabetic ketoacidosis (25% versus 2
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16

Ahmed, Asma, Kaleemullah Badini, Farah Khalid, Sahlah Sohail, and Muhammad Salik. "Comparison of ketoacidosis in type 1 and 2 diabetic patients with and without concurrent COVID-19 and determining the factors affecting their treatment and survival: a retrospective cohort study." Journal of the Pakistan Medical Association 74, no. 12 (2024): 2072–77. http://dx.doi.org/10.47391/jpma.9651.

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Objective: To assess the incidence of diabetic ketoacidosis in coronavirus disease-2019 patients and their survival rate, and to compare their outcomes with diabetic ketoacidosis patients without coronavirus disease-2019. Method: The retrospective cohort study was conducted at Aga Khan University Hospital, Karachi, and comprised data March 1, 2020, to March 31, 2021, related to patients. who had diabetic ketoacidosis with coronavirus disease-2019 in group A, and those who had diabetic ketoacidosis without coronavirus disease-2019 in group B. Data included age, gender, duration and type of diab
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17

Ahmad, Rahnuma, Mahendra Narwaria, Arya Singh, Santosh Kumar, and Mainul Haque. "Detecting Diabetic Ketoacidosis with Infection: Combating a Life-Threatening Emergency with Practical Diagnostic Tools." Diagnostics 13, no. 14 (2023): 2441. http://dx.doi.org/10.3390/diagnostics13142441.

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Background: Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes mellitus and can lead to patient demise if not immediately treated. From the recent literature, the diabetic ketoacidosis mortality rate, depending on age, is 2–5%. Insulin discontinuation and infection remain the two most common triggers for diabetic ketoacidosis. About 50% of cases of ketoacidosis result from bacterial infections like urinary tract infections and pneumonia. It is also important to diagnose the presence of infection in diabetic ketoacidosis patients to prevent the excessive use of ant
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18

Al Sadhan, Abdulmajeed, Elwaleed ElHassan, Abdulrahman Altheaby, Yousef Al Saleh, and Mahfooz Farooqui. "Diabetic Ketoacidosis in Patients with End-stage Kidney Disease: A Review." Oman Medical Journal 36, no. 2 (2021): e241-e241. http://dx.doi.org/10.5001/omj.2021.16.

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Diabetes mellitus is a highly prevalent disease. Chronic kidney disease is one of its chronic complications, and diabetic ketoacidosis is one of the most dreaded acute complications. The increasing prevalence of diabetes mellitus and renal failure has resulted in physicians increasingly encountering diabetic ketoacidosis in this complicated subgroup of patients. This review discusses the pathophysiologic understanding of diabetic ketoacidosis in patients with renal failure, its varying clinical presentation, and management and prevention. We have also highlighted the role of patient weight and
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19

Dr, Shamsila Waqar Dr Iqra Hafeez Dr Arika Waqar. "HIGH QUANTITY OF DIABETIC KETOACIDOSIS PATIENTS DURING SUMMER SEASON." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 04 (2019): 7576–81. https://doi.org/10.5281/zenodo.2640338.

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<strong><em>Objectives:</em></strong><em> The objective of this study is to review the patients of DKA (diabetic ketoacidosis) &amp; search the probable prompting features. This study carried out after the quantity of patients admitted with DKA in Services Hospital Lahore in the season of summer. </em> <strong><em>Methodology:</em></strong><em> This was a retrograde research work going through the record of all the patients admitted in the hospital suffering from diabetic ketoacidosis in the last summer season. The duration of the research was from June to August 2018. We searched for promptin
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20

Hadi, Saifullah. "Diabetic Emergency: Diabetic ketoacidosis, hyperglycemic hyperosmolar state, euglycemic diabetic ketoacidosis and hypoglycemia." International Journal of Contemporary Research in Multidisciplinary 3, no. 1 (2024): 31–37. https://doi.org/10.5281/zenodo.10474628.

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<strong>Background:</strong> Diabetic Ketoacidosis (DKA), hyperosmolar hyperglycemic states (HHS), and hypoglycemia are the most serious and fatal complications of diabetes if their diagnosis and treatment are not done on time. They will cause comas and eventually death. Dehydration is present in both DKA and HHS, but ketosis and metabolic acidosis are present only in DKA. Our aim is to find out about DKA, HHS, EDKA and hypoglycemia in diabetes mellitus patients in the Nangarhar University Teaching Hospital Medical Ward. <strong>Methods and Materials:</strong> This cross-sectional retrospectiv
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Karki, Lochan, Milan Khadka, Milan Purna Oli, et al. "Diabetic Ketoacidosis among Diabetic Patients Admitted in the Department of Medicine of a Tertiary Care Centre: A Descriptive Cross-sectional Study." Journal of Nepal Medical Association 61, no. 261 (2023): 409–12. http://dx.doi.org/10.31729/jnma.8158.

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Introduction: Diabetic ketoacidosis is one of the most severe acute complications of diabetes mellitus characterised by hyperglycemia, hyperketonemia, and metabolic acidosis. Prompt diagnosis and treatment of diabetic ketoacidosis can decrease severity, hospital stay, and possible mortality. This study aimed to find out the prevalence of diabetic ketoacidosis among diabetic patients admitted to the department of medicine of a tertiary care centre. Methods: This descriptive cross-sectional study was conducted at a tertiary care centre. Data from 1 March 2022 to 1 December 2022 were collected be
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Kartawinata, Muhammad Ikhsan, and Yusni Puspita. "A Case Report : Diabetic Ketoacidosis in patient with type 1 Diabetes Mellitus with Complication Septic Shock and AKI Stage III on HD Triggered by Perianal Abscess." Journal of Anesthesiology and Clinical Research 1, no. 1 (2020): 26–30. http://dx.doi.org/10.37275/jacr.v1i1.194.

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ABSTRACT&#x0D; Introduction. Diabetic ketoacidosis (DKA) is an acute, life-threatening complication in diabetes mellitus. Infection is a common precipitating cause of diabetic ketoacidosis (DKA) in known diabetic patient, and diabetic ketoacidosis (DKA) often presents as the first symptom of an undiagnosed diabetes. diabetic ketoacidosis (DKA) is diagnosed with combination of hyperglicaemia, acidosis metabolic and ketonuria.&#x0D; Case Presentation. A 27 years old male patient, admitted to Intensive Care Unit with decrease level of consciousness (GCS 3), he was intubated and present with respi
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Kartawinata, Muhammad Ikhsan, and Yusni Puspita. "A Case Report: Diabetic Ketoacidosis in Patient with type 1 Diabetes Mellitus with Complication Septic Shock and AKI Stage III on HD Triggered by Perianal Abscess." Journal of Anesthesiology and Clinical Research 1, no. 1 (2021): 26–30. http://dx.doi.org/10.37275/jacr.v1i1.135.

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Introduction. Diabetic ketoacidosis (DKA) is an acute, life-threatening complication in diabetes mellitus. Infection is a common precipitating cause of diabetic ketoacidosis (DKA) in known diabetic patient, and diabetic ketoacidosis (DKA) often presents as the first symptom of an undiagnosed diabetes. diabetic ketoacidosis (DKA) is diagnosed with combination of hyperglicaemia, acidosis metabolic and ketonuria.&#x0D; Case Presentation. A 27 years old male patient, admitted to Intensive Care Unit with decrease level of consciousness (GCS 3), he was intubated and present with respiratory distress
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Singh, Sandip Kumar, Shikha Rijal, Vijay Kumar Sah, Babita Khanal, and Arun Giri. "Analysis of Prolonged Pediatric Intensive Care Stay in Children with Diabetic Ketoacidosis." Journal of Nobel Medical College 9, no. 1 (2020): 46–50. http://dx.doi.org/10.3126/jonmc.v9i1.29530.

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Background: Diabetic ketoacidosis is one of most serious complication of diabetes requiring intensive care management. We aim to analyze various factors responsible for prolonged duration of stay in pediatric intensive care unit in a child with Diabetic Ketoacidosis.&#x0D; Materials and Methods: This was a hospital based prospective observational study conducted in Nobel Medical College and Teaching Hospital among children with Diabetic ketoacidosis over the period of one year. A total of 22 cases with Diabetic ketoacidosis aged 1 month to 18 years were included and clinical profile, laborator
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Hassan, Zubia, Imran Fazal, Nadeem Ashraf, Arshad Hayat, Kaswar Sajjad, and Asad Zaman. "ACUTE PANCREATITIS IN PATIENTS WITH DIABETIC KETOACIDOSIS PRESENTING AT A TERTIARY CARE UNIT." PAFMJ 71, no. 2 (2021): 606–09. http://dx.doi.org/10.51253/pafmj.v71i2.3767.

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Objective: To determine the frequency of acute pancreatitis among the patients diagnosed with diabetic ketoacidosis at our tertiary care hospital.&#x0D; Study Design: Co-relational study.&#x0D; Place and Duration of Study: Medicine department, Pak Emirates Military Hospital Rawalpindi, from Jun to Dec 2019.&#x0D; Methodology: A total of 40 cases presenting with diabetic ketoacidosis were included in our study. Diabetic ketoacidosis was diagnosed by consultant medical specialist. All patients underwent baseline investigations including serum amylase, lipid profile and CT scan abdomen in order t
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Farogh, Azfar, Muhammad Arif Mahmood, and Khalil Ahmad. "TYPE II DIABETICS." Professional Medical Journal 23, no. 02 (2016): 133–37. http://dx.doi.org/10.29309/tpmj/2016.23.02.860.

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Objectives: To determine the frequency of diabetic ketoacidosis in type IIdiabetic patients. Study Design: Cross sectional study. Setting: Department of Medicine,Sahiwal Medical College Sahiwal. Period: September 2014 to March 2015. Material andmethod: Permission was taken from Institutional review board and written informed consentwas taken from every patient. Total 189 patients with type II DM (Un-controlled) having Fastingplasma glucose level ≥126mg/dl either male or female having age 35 years to 65 years wereincluded in the study. Results: Total 189 patients with type II diabetes mellitus
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Ibrahimi, Ikramullah, Salam Jan Shams, Hayatullah Ahmadzai, and Zakirullah Sarwari. "Seasonal Variation of Diabetic Ketoacidosis in Nangarhar University Teaching Hospital." Nangarhar University International Journal of Biosciences 03, ICCC(special) (2024): 14–17. http://dx.doi.org/10.70436/nuijb.v3i02.149.

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Diabetic ketoacidosis is a life threating acute complication of diabetes mellitus aquiring special care. The aim of the study was to find out seasonal variation in the prevalence of diabetic ketoacidosis in diabetic patients. It was a cross sectional hospital based study conducted over both male and female diabetic patients admitter at the internal medicine ward of Nangarhar University Teaching Hospital during one year. Mean age across DKA was 53.9 ± 14 for DKA negative patients versus 51.3 ± 17.2 for DKA positive patients, P value = 0.26. Winter season was demonstrated with peak DKA positive
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Valenzuela-Vallejo, Laura, Sofía A. López-Ramírez, Verónica Morales-Burton, Sara Aguilera-Martínez, Martha I. Álvarez-Olmos, and Paola Durán-Ventura. "Pediatric diabetic ketoacidosis as type 1 diabetes debut with concurrent SARS-CoV-2 infection: A case report." SAGE Open Medical Case Reports 10 (January 2022): 2050313X2210972. http://dx.doi.org/10.1177/2050313x221097263.

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Diabetic ketoacidosis is a life-threatening complication associated with type 1 diabetes (T1D). Recent evidence suggests that SARS-CoV-2 could trigger diabetic ketoacidosis in type 1 diabetes susceptibility and previous insulitis; however, the data on SARS-CoV-2-infected patients with diabetic ketoacidosis as their type 1 diabetes are still limited. We report a 13-year-old Latinamerican male with symptoms and laboratory tests diagnostic of diabetic ketoacidosis and positive SARS-CoV-2 reverse transcription polymerase chain reaction, who required mild COVID-19 care management, fluid resuscitati
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Guzmán, Guillermo Edinson, Veline Martínez, Sebastián Romero, María Mercedes Cardozo, María Angélica Guerra, and Oriana Arias. "Combined hyperglycemic crises in adult patients already exist in Latin America." Biomédica 44, Sp. 1 (2024): 110–18. http://dx.doi.org/10.7705/biomedica.6912.

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Introduction. Diabetes mellitus is one of the most common diseases worldwide, with a high morbidity and mortality rate. Its prevalence has been increasing, as well as its acute complications, such as hyperglycemic crises. Hyperglycemic crises can present with combined features of diabetic ketoacidosis and hyperosmolar state. However, their implications are not fully understood.Objective. To describe the characteristics, outcomes, and complications of the diabetic population with hyperglycemic crises and to value the combined state in the Latin American population.Materials and methods. Retrosp
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Domínguez Rojas, Jesús Ángel, Mariela Violeta Tello Pezo, Jaime Tasayco Muñoz, and Álvaro Coronado Muñoz. "Severe diabetic ketoacidosis precipitated by COVID-19 in pediatric patients: Two case reports." Medwave 21, no. 03 (2021): e8176-e8176. http://dx.doi.org/10.5867/medwave.2021.03.8176.

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Introduction The association of COVID-19 with diabetes mellitus is bidirectional. In one direction, diabetes mellitus is associated with an increased risk of severe COVID-19. In the opposite direction, in patients with COVID-19 new-onset diabetes mellitus, severe diabetic ketoacidosis and severe metabolic complications have been described. Clinical case This report describes two patients with diabetes mellitus who came to our hospital with ketoacidosis resulting from new-onset diabetes mellitus. We describe the clinical course and the management approach during the COVID-19 pandemic. Conclusio
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Nurhakim, Lukman, Rudy Afriant, and Dinda Aprilia. "Diabetic Ketoacidosis in Type 1 Diabetes Mellitus." Sumatera Medical Journal 7, no. 1 (2024): 51–54. http://dx.doi.org/10.32734/sumej.v7i1.11837.

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Introduction: Diabetic ketoacidosis (DKA) is a state of metabolic decompensation/disorder characterized by the triad of hyperglycemia, acidosis and ketosis, caused by absolute or relative insulin deficiency and increased counter-regulatory hormones. Immediate therapy in DKA patients determines the patient's prognosis Case Report: A 19-year-old male treated in the internal medicine ward of Dr. M djamil Padang with diabetic ketoacidosis, type 1 DM, and Abscess capitis. The patient was treated with rehydration and intravenous insulin infusion can show clinical improvement. Conclusion: The diagnos
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Coutada, Rosália S., Soraia S. Cunha, Elisabete S. Gonçalves, Ana P. Gama, João P. Silva, and Paula M. Pinheiro. "Diabetic ketoacidosis in pregnancy." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 7 (2018): 2945. http://dx.doi.org/10.18203/2320-1770.ijrcog20182912.

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Diabetic ketoacidosis in pregnancy is a rare but potential life-threatening condition for the mother and the fetus. It tends to occur latter in pregnancy and is more common in patients with pregestational diabetes. Obstetricians should be aware of the events that can trigger diabetic ketoacidosis in pregnancy. Prompt recognition and aggressive treatment of this condition are essential in order to reduce perinatal mortality and morbidity. The authors present a case of a pregnant woman with type 1 diabetes with a poor surveillance of pregnancy and noncompliance to treatment that develops severe
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Hamed, Sherifa, Kotb Abbass Metwalley, Hekma Saad Farghaly, and Tahra Sherief. "Serum Levels of Neuron-Specific Enolase in Children With Diabetic Ketoacidosis." Journal of Child Neurology 32, no. 5 (2017): 475–81. http://dx.doi.org/10.1177/0883073816686718.

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Neuron-specific enolase is a sensitive marker of neuronal damage in various neurologic disorders. This study aimed to measure serum neuron-specific enolase levels at different time points and severities of diabetic ketoacidosis. This study included 90 children (age 9.2 ± 3.4 years) with diabetic ketoacidosis. Neuron-specific enolase was measured at 3 time points (baseline and after 12 and 24 hours of starting treatment). Among patients, 74.4% had diagnosis of new diabetes, 60% had Glasgow Coma Scale score &lt;15, and 75.6% had moderate/severe diabetic ketoacidosis. Compared with controls (n =
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Ahmed, Ashraf Uddin, Muhammad Abdur Rahim, Md Raziur Rahman, Reshad Falah Nazim, and Khwaja Nazim Uddin. "Diabetic Ketoacidosis: Pattern of Precipitating Causes." Journal of Enam Medical College 4, no. 2 (2014): 94–97. http://dx.doi.org/10.3329/jemc.v4i2.19676.

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Background: Diabetic ketoacidosis (DKA) is one of the most common acute complications of diabetes mellitus (DM). DKA is a recognised presenting feature of type 1 DM, but it commonly complicates previously diagnosed diabetic patients of all types, specially if they get infection or discontinue treatment. Objective: To describe the precipitating causes of DKA. Materials and Methods: This cross-sectional study was done from September to November, 2010 in Bangladesh Institute of Research &amp; Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM). Diagnosed DKA cases were evaluate
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Hasković, Edhem, Azra Bureković, Adnan Husić, Muhamed Fočak, and Erna Islamagić. "Acid-Base Status of Patients with Diabetic Ketoacidosis and Ketonuria: Bosnia and Herzegovina Experience." Acta Facultatis Medicae Naissensis 35, no. 2 (2018): 132–39. http://dx.doi.org/10.2478/afmnai-2018-0015.

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Abstract The aim of this study was to analyze the values of biochemical parameters in patients with diabetic ketoacidosis and ketonuria. In this prospective comparative study conducted at the Clinical Center of the University of Sarajevo, hundred patients of both genders with diabetes mellitus were enrolled. Newly diagnosed diabetic patients with complications like acute ketoacidosis (n = 50) and ketonuria (n = 50) were included in this study and compared. The values of biochemical parameters in these patients were analyzed. We found that mean values of pH, base excess, hydrogencarbonate, sodi
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36

Stinkens, Kirsten, and Chantal Mathieu. "Sodium-glucose Cotransporter 2 Inhibitors and Ketoacidosis – Clinical Implications in the Treatment of Patients with Type 2 Diabetes." European Endocrinology 12, no. 1 (2016): 33. http://dx.doi.org/10.17925/ee.2016.12.01.33.

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The use of sodium-glucose cotransporter 2 inhibitors is associated with an increased risk of diabetic ketoacidosis. This risk has been reported in particular in off-label use of these agents in type 1 diabetes, but reports of risks in type 2 diabetes patients also exist. In type 2 diabetes ketoacidosis is rare and is present particularly in patients who have undergone prolonged starvation, serious infection, alcohol abuse or surgery. The pleiotropic advantages of sodium-glucose cotransporter 2 inhibitors do not outweigh the risk for a diabetic ketoacidosis, but caution is warranted.
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Birhanu, Abebe, Sintayehu Ambachew, Netsanet Baye, et al. "Prevalence and associated factors of diabetic ketoacidosis among patients with diabetes mellitus at the University of Gondar Comprehensive and Specialized Referral Hospital Northwest, Ethiopia." PLOS ONE 20, no. 2 (2025): e0318775. https://doi.org/10.1371/journal.pone.0318775.

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Background Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Diabetic ketoacidosis is one of the life-threatening complications in diabetic individuals with, high morbidity and mortality globally. However, the data related to the prevalence and associated factors of diabetic ketoacidosis are limited in the study setting. Objective To assess the prevalence of diabetic ketoacidosis and its associated factors among diabetic mellitus patients at the University of Gondar Comprehensive Specialized Hospital.
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Gusti, Ayu Sri Ari Swandewi, and Windiyanto Romy. "Recurrent Diabetic Ketoacidosis in Adolescents with Type 1 Diabetes Mellitus." INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND BIO-MEDICAL SCIENCE 04, no. 11 (2024): 881–88. https://doi.org/10.5281/zenodo.14202466.

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<strong>Introduction:</strong>&nbsp;Diabetic ketoacidosis (DKA) is one of the serious complications that is often found in pediatric cases of type 1 diabetes mellitus (DM). Diabetic ketoacidosis mostly occurs in patients with low glycemic control. Currently, many studies are assessing risk factors for recurrent ketoacidosis, including young age, male gender, patients with comorbidities (psychiatric diseases, alcohol or substance abuse, other chronic diseases), and patients with socioeconomic factors. The incidence of recurrent diabetic ketoacidosis in children and adolescents is becoming more
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de Sá-Ferreira, Caio Oliveira, Camila Helena Macedo da Costa, João Campos Wiltgen Guimarães, et al. "Diabetic ketoacidosis and COVID-19: what have we learned so far?" American Journal of Physiology-Endocrinology and Metabolism 322, no. 1 (2022): E44—E53. http://dx.doi.org/10.1152/ajpendo.00244.2021.

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In December 2019, a pandemic emerged due to a new coronavirus that imposed various uncertainties and discoveries. It has been reported that diabetes is a risk factor for worst outcomes of COVID-19 and also that SARS-CoV-2 infection was correlated with the occurrence of diabetic ketoacidosis (DKA) in patients. The aim of this work is to discuss this correlation emphasizing the main case reports from 2020 while exploring the management of DKA during the course of COVID-19. Web of Science, PubMed, and Scopus databases were searched using two sets of Medical Subject Heading (MeSH) search terms or
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Kalantzis, Christos, and Kalliopi Pappa. "Diabetic ketoacidosis in pregnancy." Hellenic Journal of Obstetrics and Gynecology 18, no. 1 (2019): 21–25. http://dx.doi.org/10.33574/hjog.1678.

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Diabetic ketoacidosis in pregnancy is a rare but potential life-threatening condition for the mother and the fetus. Although predictably DKP is more common in patients with type 1 diabetes, it has been reported too in those with type 2 diabetes as well as gestational diabetes. Diabetic ketoacidosis usually occurs in the second and third trimesters because of insulin resistance. Prompt recognition and aggressive treatment of this condition are essential in order to reduce perinatal mortality and morbidity. Despite improvement in its incidence rates and outcomes over the years, it still remains
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Hassannezhad, Reshad. "Hyperketonemia: Clinical features and diagnosis of Diabetic Ketoacidosis." Endocrinology and Disorders 2, no. 5 (2018): 01–04. http://dx.doi.org/10.31579/2640-1045/098.

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Diets that boost ketone production are increasingly used for treating several neurological disorders. Elevation in ketones in most cases is considered favorable, as they provide energy and are efficient in fueling the body's energy needs.Several physiological and pathological triggers, such as fasting, ketogenic diet, and diabetes cause an accumulation and elevation of circulating ketones. Complications of the brain, kidney, liver, and microvasculature were found to be elevated in diabetic patients who had elevated ketones compared to those diabetics with normal ketone levels. Diabetic ketoaci
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Hassannezhad, Reshad. "Hyperketonemia: Clinical features and diagnosis of Diabetic Ketoacidosis." Endocrinology and Disorders 2, no. 5 (2018): 01–04. http://dx.doi.org/10.31579/2640-1045/033.

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Diets that boost ketone production are increasingly used for treating several neurological disorders. Elevation in ketones in most cases is considered favorable, as they provide energy and are efficient in fueling the body's energy needs.Several physiological and pathological triggers, such as fasting, ketogenic diet, and diabetes cause an accumulation and elevation of circulating ketones. Complications of the brain, kidney, liver, and microvasculature were found to be elevated in diabetic patients who had elevated ketones compared to those diabetics with normal ketone levels. Diabetic ketoaci
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43

Albuali, Waleed H., Abdullah A. Yousef, Mohammad H. Al-Qahtani, et al. "A Clinical and Biochemical Comparative Study Of Diabetic Ketoacidosis (DKA) in Newly Diagnosed Vs Known Cases of Type 1 Diabetic Children." Review of Diabetic Studies 19, no. 1 (2023): 28–33. http://dx.doi.org/10.1900/rds.2023.19.28.

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Objectives: We aimed to study the characterizing clinical and biochemical profiles of Diabetic Ketoacidosis (DKA) in children with newly diagnosed Type 1 Diabetes Mellitus (Type 1DM) compared to children with established diagnosis of Type 1DM presenting with DKA admitted to the pediatric intensive care unit of a large university hospital in the eastern region of Saudi Arabia. Methods: We retrospectively reviewed the medical records of 211 patients who were admitted to the pediatric intensive care unit with diabetic ketoacidosis between 2010 and 2019. The diagnosis of diabetic ketoacidosis was
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Asim, Muhammad, Aliena Badshah, Durkho Atif, and Wazir Mohammad. "FREQUENCY OF RISK FACTORS ASSOCIATED WITH DIABETIC KETOACIDOSIS IN PATIENTS PRESENTING AT KHYBER TEACHING HOSPITAL PESHAWAR." Journal of Medical Sciences 31, no. 4 (2023): 286–89. http://dx.doi.org/10.52764/jms.23.31.4.6.

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Objectives: To determine the frequency of risk factors associated with diabetic ketoacidosis in patients presenting at Khyber Teaching Hospital Peshawar. Materials and methods: Patients of either gender, aged between 18 and 60 years, with either type I or type II diabetes mellitus presenting with diabetic ketoacidosis with the duration of diabetes &gt; 1 year were included in the study. DKA was diagnosed based on the clinical presentation of respective patients, serum Random Blood Sugar (RBS), and urinary ketones. Careful scrutinization was done for the detection of common risk factors for DKA
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Dr., Muhammad Kashif Dr. Hafiz Umer Hussaan Ahmad Zarif Khan. "A DESCRIPTIVE CROSS-SECTIONAL RESEARCH TO ASSESS THE INVOLVEMENT OF BIOCHEMICAL PROFILE & CLINICAL MANIFESTATIONS IN DIABETIC KETOACIDOSIS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 10 (2018): 10992–97. https://doi.org/10.5281/zenodo.1473086.

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<strong><em>Objectives: </em></strong><em>We aimed to assess the biochemical and clinical characteristics and profile in the patients of </em><em>diabetic ketoacidosis</em> <strong><em>Material and methods: </em></strong><em>We completed this </em><em>cross-sectional research at Mayo Hospital, Lahore in the timeframe of February to October 2017 on a total of fifty diabetic ketoacidosis patients who met the inclusion guidelines of this particular research. We completed biochemical profile and clinical features comparison in each patient diagnosed with diabetic ketoacidosis.</em> <strong><em>Res
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Al-Qahtani, Mohammad Hussain, Aqilah Taleb Al-Qassab, Fatimah Mousa Bukhamseen, et al. "Severity and Resolution of Diabetic Ketoacidosis in Newly Diagnosed Type 1 Diabetic Children before and During The COVID-19 Pandemic." Review of Diabetic Studies 18, no. 4 (2022): 181–86. http://dx.doi.org/10.1900/rds.2022.18.181.

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OBJECTIVES: To epidemiologically assess the influence of COVID-19 pandemic on newly diagnosed type 1 diabetes mellitus presenting with diabetic ketoacidosis at the teaching hospital of the university, Eastern province, Saudi Arabia. METHODS: We enrolled newly diagnosed type 1 diabetes mellitus cases among pediatric patients attending the emergency department and outpatient clinics during 2019-2021. The participants' data were collected from electronic medical records which included patients' age at diagnosis, sex, nationality, height, weight, year of diagnosis, length of stay, presentation, ra
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Kavin, Kumar, Maheshwari Sanjiv, Yadav Yadram, Devgan Yash, Sankol Anil, and Gupta Gaurav. "To Assess the Correlation of Serum Phosphorus Level in Diabetic Ketoacidosis in Type-2 Diabetes Mellitus." International Journal of Pharmaceutical and Clinical Research 15, no. 11 (2023): 1029–31. https://doi.org/10.5281/zenodo.11224355.

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Background: In DKA patients, phosphate and magnesium level are decreased and further reduction may occur during insulin treatment. But, usually, these electrolytes are not given, when the patient takes oral diet. If the phosphate level is low, and the patient is not taking oral diet, potassium phosphate can be given. If magnesium level found low level in DKA patient, who developed cardiac arrhythmias, magnesium sulfate can be given. Otherwise, routine supplementation is not needed. Methods: Phosphorus levels was estimated on 1 day, 3 day and discharge/worsening of patient. It was correlated to
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Ayesha Shahid, Batool Fatima, Yasir Naqi Khan, Mohsina Noor Ibrahim, and Jamal Raza. "Early suspicion can save lives; mucormycosis in two children with diabetic ketoacidosis in Pakistan." Journal of the Pakistan Medical Association 72, no. 4 (2022): 790–92. http://dx.doi.org/10.47391/jpma.1659.

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Background: Mucormycosis is a cause of fulminant necrotizing fungal infection in children with underlying immunocompromising condition. Rhino-orbito-cerebral infection is the most common form of mucormycosis in children with uncontrolled diabetes mellitus or diabetic ketoacidosis. Once considered a rare entity is now increasingly being reported especially in the diabetic population. The initial presentation can mimic a bacterial infection, thus a high index of suspicion is needed for timely intervention to reduce morbidity and mortality.Case report: We present a case of rhino-orbito-cerebral m
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Miolski, Jelena, Maja Ješić, Smiljka Kovačević, Jelena Blagojević, and Vera Zdravković. "Diabetic ketoacidosis: Our experiences." Medicinski casopis 55, no. 2 (2021): 71–74. http://dx.doi.org/10.5937/mckg55-31440.

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Diabetic ketoacidosis is an acute complication in children with type 1 diabetes mellitus. It is diagnosed if the sugar value is &gt; 11 mmol / l, pH &lt;7.3, HCO3≤ 15 mmol / l, with ketonemia or ketonuria. Based on serum pH and bicarbonate values it could be mild, moderate, and severe. It is manifested by rapid breathing, abdominal pain, nausea, vomiting, altered state of consciousness. Early recognition of symptoms prevents the possibility of serious complications. Treatment includes fluid replacement, rehydration, insulin therapy, electrolyte replacement, glucose correction. This paper prese
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Mattoo, Arif Ishtiq, Indraneel Dasgupta, Subhendu Das, et al. "Atypical Diabetic Ketoacidosis in a Young Female." Indian Journal of Emergency Medicine 4, no. 1 (2018): 49–52. http://dx.doi.org/10.21088/ijem.2395.311x.4118.9.

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Diabetic ketoacidosis is a life threatning complication of Diabetes Milletus and can be catastrophic if left untreated.Being one of the most common complications but sometime with no clear history and symptoms the diagnosis become difficult. Hence emergency physicians should keep a broad vision while dealing with young patients with high glucose level. Diabetic ketoacidosis may be the first symptom of previously undiagnosed Diabetes. It is diagnosed with combination of Hyperglycemia, Acidosis and Ketonuria. Patients with prolonged acidosis and tendency to hypokalemia should be investigated for
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