Log in

Relevant bibliographies by topics / Diabetic Retinopathy (DR) is the major cause of blindness in working age adults

Contents

Journal articles

Academic literature on the topic 'Diabetic Retinopathy (DR) is the major cause of blindness in working age adults'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Diabetic Retinopathy (DR) is the major cause of blindness in working age adults.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Diabetic Retinopathy (DR) is the major cause of blindness in working age adults"

1

Zhu, Xiao-feng, and Hai-dong Zou. "PEDF in Diabetic Retinopathy: A Protective Effect of Oxidative Stress." Journal of Biomedicine and Biotechnology 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/580687.

Full text

Abstract:

Diabetic retinopathy (DR) is a major cause of blindness in working age adults, and oxidative stress plays a vital role in the pathogenesis of DR. Pigment-epithelium-derived factor (PEDF), a multifunctional protein, has shown to inhibit the development of DR by accumulating evidence. This paper highlights the current understanding of probable mechanism about how PEDF blocks the deterioration of DR through its antioxidative properties and application prospects of PEDF as a novel therapeutic target in DR. Gene therapy of PEDF is becoming more and more acceptable and will widely be applied to the

APA, Harvard, Vancouver, ISO, and other styles

2

Khansari, Maziyar M., William D. O’Neill, Richard D. Penn, Norman P. Blair, and Mahnaz Shahidi. "Detection of Subclinical Diabetic Retinopathy by Fine Structure Analysis of Retinal Images." Journal of Ophthalmology 2019 (July 4, 2019): 1–6. http://dx.doi.org/10.1155/2019/5171965.

Full text

Abstract:

Background and Objective. Diabetic retinopathy (DR) is a major complication of diabetes and the leading cause of blindness among US working-age adults. Detection of subclinical DR is important for disease monitoring and prevention of damage to the retina before occurrence of vision loss. The purpose of this retrospective study is to describe an automated method for discrimination of subclinical DR using fine structure analysis of retinal images. Methods. Discrimination between nondiabetic control (NC; N = 16) and diabetic without clinical retinopathy (NDR; N = 17) subjects was performed using

APA, Harvard, Vancouver, ISO, and other styles

3

Sharma, Kusum, Vikas Malik, Alpa Agrawal, and Nikita Paliya. "Diabetic Retinopathy (DR): The Silent Threat." International Research Journal of Medicine and Surgery 02, no. 01 (2025): 11–15. https://doi.org/10.47857/irjmeds.2025.v02i01.022.

Full text

Abstract:

Diabetic retinopathy (DR) is a common yet often undiagnosed complication of diabetes mellitus, leading to vision impairment and potential blindness if left untreated. It is a major cause of vision loss among working-age adults worldwide, with its prevalence increasing alongside the global rise in diabetes. DR results from prolonged hyperglycemia, which damages the small blood vessels of the retina, progressing from mild non-proliferative stages to severe proliferative retinopathy. In advanced stages, complications such as retinal hemorrhage and detachment may occur. Because early DR is typical

APA, Harvard, Vancouver, ISO, and other styles

4

Aragonès, Gemma, Sheldon Rowan, Sarah G Francisco, et al. "Glyoxalase System as a Therapeutic Target against Diabetic Retinopathy." Antioxidants 9, no. 11 (2020): 1062. http://dx.doi.org/10.3390/antiox9111062.

Full text

Abstract:

Hyperglycemia, a defining characteristic of diabetes, combined with oxidative stress, results in the formation of advanced glycation end products (AGEs). AGEs are toxic compounds that have adverse effects on many tissues including the retina and lens. AGEs promote the formation of reactive oxygen species (ROS), which, in turn, boost the production of AGEs, resulting in positive feedback loops, a vicious cycle that compromises tissue fitness. Oxidative stress and the accumulation of AGEs are etiologically associated with the pathogenesis of multiple diseases including diabetic retinopathy (DR).

APA, Harvard, Vancouver, ISO, and other styles

5

Simó-Servat, Olga, Cristina Hernández, and Rafael Simó. "Usefulness of the Vitreous Fluid Analysis in the Translational Research of Diabetic Retinopathy." Mediators of Inflammation 2012 (2012): 1–11. http://dx.doi.org/10.1155/2012/872978.

Full text

Abstract:

Diabetic retinopathy (DR) is the major cause of acquired blindness in working-age adults. Current treatments for DR (laser photocoagulation, intravitreal corticosteroids, intravitreal antivascular endothelial growth factor (VEGF) agents, and vitreo-retinal surgery) are applicable only at advanced stages of the disease and are associated with significant adverse effects. Therefore, new pharmacological treatments for the early stages of the disease are needed. Vitreous fluid obtained from diabetic patients undergoing vitreoretinal surgery is currently used to explore the events that are taking p

APA, Harvard, Vancouver, ISO, and other styles

6

Gucciardo, Erika, Sirpa Loukovaara, Petri Salven, and Kaisa Lehti. "Lymphatic Vascular Structures: A New Aspect in Proliferative Diabetic Retinopathy." International Journal of Molecular Sciences 19, no. 12 (2018): 4034. http://dx.doi.org/10.3390/ijms19124034.

Full text

Abstract:

Diabetic retinopathy (DR) is the most common diabetic microvascular complication and major cause of blindness in working-age adults. According to the level of microvascular degeneration and ischemic damage, DR is classified into non-proliferative DR (NPDR), and end-stage, proliferative DR (PDR). Despite advances in the disease etiology and pathogenesis, molecular understanding of end-stage PDR, characterized by ischemia- and inflammation-associated neovascularization and fibrosis, remains incomplete due to the limited availability of ideal clinical samples and experimental research models. Sin

APA, Harvard, Vancouver, ISO, and other styles

7

Zhang, Jingfa, Jingxiang Zhang, Chaoyang Zhang, et al. "Diabetic Macular Edema: Current Understanding, Molecular Mechanisms and Therapeutic Implications." Cells 11, no. 21 (2022): 3362. http://dx.doi.org/10.3390/cells11213362.

Full text

Abstract:

Diabetic retinopathy (DR), with increasing incidence, is the major cause of vision loss and blindness worldwide in working-age adults. Diabetic macular edema (DME) remains the main cause of vision impairment in diabetic patients, with its pathogenesis still not completely elucidated. Vascular endothelial growth factor (VEGF) plays a pivotal role in the pathogenesis of DR and DME. Currently, intravitreal injection of anti-VEGF agents remains as the first-line therapy in DME treatment due to the superior anatomic and functional outcomes. However, some patients do not respond satisfactorily to an

APA, Harvard, Vancouver, ISO, and other styles

8

Liu, Fang, Alan B. Saul, Prahalathan Pichavaram, et al. "Pharmacological Inhibition of Spermine Oxidase Reduces Neurodegeneration and Improves Retinal Function in Diabetic Mice." Journal of Clinical Medicine 9, no. 2 (2020): 340. http://dx.doi.org/10.3390/jcm9020340.

Full text

Abstract:

Diabetic retinopathy (DR) is a significant cause of blindness in working-age adults worldwide. Lack of effective strategies to prevent or reduce vision loss is a major problem. Since the degeneration of retinal neurons is an early event in the diabetic retina, studies to characterize the molecular mechanisms of diabetes-induced retinal neuronal damage and dysfunction are of high significance. We have demonstrated that spermine oxidase (SMOX), a mediator of polyamine oxidation is critically involved in causing neurovascular damage in the retina. The involvement of SMOX in diabetes-induced retin

APA, Harvard, Vancouver, ISO, and other styles

9

Zhou, Jing, and Bo Chen. "Retinal Cell Damage in Diabetic Retinopathy." Cells 12, no. 9 (2023): 1342. http://dx.doi.org/10.3390/cells12091342.

Full text

Abstract:

Diabetic retinopathy (DR), the most common microvascular complication that occurs in diabetes mellitus (DM), is the leading cause of vision loss in working-age adults. The prevalence of diabetic retinopathy is approximately 30% of the diabetic population and untreated DR can eventually cause blindness. For decades, diabetic retinopathy was considered a microvascular complication and clinically staged by its vascular manifestations. In recent years, emerging evidence has shown that diabetic retinopathy causes early neuronal dysfunction and neurodegeneration that may precede vascular pathology a

APA, Harvard, Vancouver, ISO, and other styles

10

Matos, Ana L., Diogo F. Bruno, António F. Ambrósio, and Paulo F. Santos. "The Benefits of Flavonoids in Diabetic Retinopathy." Nutrients 12, no. 10 (2020): 3169. http://dx.doi.org/10.3390/nu12103169.

Full text

Abstract:

Diabetic retinopathy (DR), one of the most common complications of diabetes, is the leading cause of legal blindness among adults of working age in developed countries. After 20 years of diabetes, almost all patients suffering from type I diabetes mellitus and about 60% of type II diabetics have DR. Several studies have tried to identify drugs and therapies to treat DR though little attention has been given to flavonoids, one type of polyphenols, which can be found in high levels mainly in fruits and vegetables, but also in other foods such as grains, cocoa, green tea or even in red wine. Flav

APA, Harvard, Vancouver, ISO, and other styles

More sources

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!