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Dissertations / Theses on the topic 'Diagnosis in vitro'

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1

Al-Ketheree, Zainab A. N. "In vitro tests for the diagnosis of aspirin and salicylate sensitivity." Thesis, Cardiff Metropolitan University, 2004. http://hdl.handle.net/10369/6491.

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Sensitivity to aspirin, non-steroidal anti-inflammatory drugs (NSAIDs) and also dietary salicylate is an increasingly important and observed phenomenon. The reliable diagnosis of individuals with these disorders is of great importance, given the use of these drugs as a prophylactic medication. Many of the symptoms seen in patients associated with this sensitivity to these drugs include dermatitis, nasal polyps, persistent cough, rhinitis, skin problems, stomach irritation, swelling of face and urticaria are also seen in salicylate intolerance. These symptoms are similar to those seen in the al
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2

Wood, Andrew J. "A study of cation transport in vivo and in vitro in affective illness." Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.235953.

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Browne, Jacinta. "Diagnostic ultrasound real-time and colour Doppler imaging assessed by in-vivo and in-vitro methods." Thesis, University of Glasgow, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272856.

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4

Farajipour, Parisa. "In Vitro Biomarker Detection for Early Diagnosis of Neurodegenerative Diseases via the Ocular Fluid." University of Akron / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=akron1259778648.

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5

Ashtekar, Koustubh D. "Guidewire Flow Obstruction Effect on Diagnosis of Coronary Lesion Severity: In-Vitro Experimental and Numerical Study." Cincinnati, Ohio : University of Cincinnati, 2006. http://www.ohiolink.edu/etd/view.cgi?acc%5Fnum=ucin1163376181.

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Thesis (M.S.)--University of Cincinnati, 2006.<br>Advisor: Dr. Rupak K. Banerjee. Title from electronic thesis title page (viewed May 15, 2008). Includes abstract. Keywords: Coronary stenosis; guidewire; diagnosis; FFR; CFR; Steady and pulsatile flow; Pressure drop coefficient; Diffuser performance coefficient. Includes bibliographical references.
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MENDONCA, MARIA A. L. C. "Laser e diagnostico de caries: estado da arte e avaliacao in vitro das diferencas de fluorescencia entre esmalte sadio, cariado e desmineralizado." reponame:Repositório Institucional do IPEN, 2001. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10955.

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7

Diniz, Michele Baffi [UNESP]. "Efetividade da fluorescência a laser no diagnóstico de lesões de cárie. Estudos in vitro e in vivo." Universidade Estadual Paulista (UNESP), 2006. http://hdl.handle.net/11449/95502.

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Made available in DSpace on 2014-06-11T19:27:48Z (GMT). No. of bitstreams: 0 Previous issue date: 2006Bitstream added on 2014-06-13T18:31:58Z : No. of bitstreams: 1 diniz_mb_me_arafo.pdf: 3188878 bytes, checksum: afb48495eaac71c8663023ac0c8eba58 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>O objetivo do presente estudo foi avaliar a efetividade da fluorescência a laser (KaVo DIAGNOdent) para a determinação da severidade de lesões de cárie oclusal em dentes permanentes in vivo e para determinação da remineralização in vitro de lesões de cárie induzidas artif
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8

Foncy, Julie. "Nouvelles technologies intégrées d'adressage et de détection des interactions moléculaires pour application de biopuces en diagnostic moléculaire in vitro." Thesis, Toulouse, INSA, 2013. http://www.theses.fr/2013ISAT0043/document.

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Le marché du diagnostic connait un essor considérable depuis l’avènement de labiologie moléculaire. Plus précis et souvent plus rapide, le diagnostic moléculaire in vitro(DIV) est de plus en plus utilisé dans les laboratoires d’analyses médicales. L’ensemble destests dédiés au marché du DIV répond à des contraintes socio-économiques très précisescomme : la fiabilité du résultat, le délai de réponse court, le faible coût et la facilitéd’utilisation. Les indicateurs socio-économiques montrent que la technologie des biopuces estun potentiel bon candidat pour répondre aux attentes du marché. En ef
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9

ROCHA-CABRAL, RENATA M. "Detecção de lesões de cárie por fluorescência: correlação entre a histologia e os resultados obtidos com o DIAGNOdent e a espectroscopia." reponame:Repositório Institucional do IPEN, 2006. http://repositorio.ipen.br:8080/xmlui/handle/123456789/11437.

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10

Seliktar, Dror. "Dynamic mechanical conditioning regulates the development of cell-seeded collagen constructs in vitro : implications for tissue-engineered blood vessels." Diss., Georgia Institute of Technology, 2000. http://hdl.handle.net/1853/25674.

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11

Silva, Carlos Alberto Brigoni e. "Emprego do sêmen criopreservado e capacitado in vitro na inseminação artificial intracervical superficial em ovinos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/55991.

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A inseminação artificial intracervical superficial em ovinos é uma técnica simples, de baixo custo e eficiente no emprego do sêmen fresco. Por outro lado, particularidades do aparelho reprodutivo da fêmea ovina, a quantidade de células espermáticas que sobrevivem ao pós-congelamento bem como a capacitação precoce de espermatozóides durante o processo de criopreservação, impedem o emprego desta técnica com sêmen criopreservado, fazendo-se necessária a deposição intrauterina, com auxílio da laparoscopia. Desconhece-se a eficiência da inseminação artificial intracervical superficial em ovinos, em
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12

Souza, Juliana Feltrin de [UNESP]. "Desempenho de métodos baseados na indução de fluorescência para a detecção de lesões de cárie em superfícies oclusais e proximais: estudos in vitro." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/88704.

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Made available in DSpace on 2014-06-11T19:23:35Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-03-22Bitstream added on 2014-06-13T19:29:51Z : No. of bitstreams: 1 souza_jf_me_arafo.pdf: 3284885 bytes, checksum: 881b633adafdc61e86d920b11bc5ff19 (MD5)<br>As propostas dos estudos foram avaliar in vitro: o desempenho do exame visual (ICDAS), do exame radiográfico convencional e de métodos baseados em indução de fluorescência, DIAGNOdent 2095 (DD, Kavo, Biberach, Alemanha), DIAGNOdent 2190 (DDpen, Kavo, Biberach, Alemanha) e câmera intraoral VistaProof (CI, Dürr Dental, Bietigheim-Bissing
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Diniz, Michele Baffi. "Efetividade da fluorescência a laser no diagnóstico de lesões de cárie. Estudos in vitro e in vivo /." Araraquara : [s.n.], 2006. http://hdl.handle.net/11449/95502.

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Orientador: Rita de Cássia Loiola Cordeiro<br>Banca: Fausto Medeires Mendes<br>Banca: Lourdes Aparecida Martins dos Santos Pinto<br>Resumo: O objetivo do presente estudo foi avaliar a efetividade da fluorescência a laser (KaVo DIAGNOdent) para a determinação da severidade de lesões de cárie oclusal em dentes permanentes in vivo e para determinação da remineralização in vitro de lesões de cárie induzidas artificialmente em esmalte de dentes bovinos. No estudo in vitro, 78 blocos de esmalte com lesões de cárie artificial (mancha branca) com valores de dureza Vickers de 38,48 l 0,85 foram submeti
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14

Andrade, Tânia Maria de. "GESTÃO DE RESÍDUOS EM EMPRESAS DE DIAGNÓSTICO IN VITRO: ESTUDO DE CASO EM UMA INDÚSTRIA GOIANA." Pontifícia Universidade Católica de Goiás, 2009. http://localhost:8080/tede/handle/tede/2586.

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Made available in DSpace on 2016-08-10T10:45:07Z (GMT). No. of bitstreams: 1 TANIA MARIA DE ANDRADE.pdf: 1841439 bytes, checksum: e431d775b9e758e03078822f73259e49 (MD5) Previous issue date: 2009-08-13<br>This dissertation was established with the objective of verifying whether the existing legislation, specific to the type of company under study, helps ensure the sustainability of the process and the environment. Hopes are still evident that the volume of waste generated during the production process the company is small, and only a fraction of that requires treatment before its disposal, so
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TEODORO, RODRIGO. "Avaliação pré-clínica do análogo da neurotensina(8-13) radiomarcado com sup(99m)Tc: caracterização in vitro e in vivo." reponame:Repositório Institucional do IPEN, 2010. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9538.

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Made available in DSpace on 2014-10-09T12:27:46Z (GMT). No. of bitstreams: 0<br>Made available in DSpace on 2014-10-09T14:05:01Z (GMT). No. of bitstreams: 0<br>Tese (Doutoramento)<br>IPEN/T<br>Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP
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Souza, Juliana Feltrin de. "Desempenho de métodos baseados na indução de fluorescência para a detecção de lesões de cárie em superfícies oclusais e proximais : estudos in vitro /." Araraquara : [s.n.], 2010. http://hdl.handle.net/11449/88704.

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Orientador: Rita de Cássia Loiola Cordeiro<br>Banca: Lourdes Aparecida Martins dos Santos Pinto<br>Banca: Jonas de Almeida Rodrigues<br>Resumo: As propostas dos estudos foram avaliar in vitro: o desempenho do exame visual (ICDAS), do exame radiográfico convencional e de métodos baseados em indução de fluorescência, DIAGNOdent 2095 (DD, Kavo, Biberach, Alemanha), DIAGNOdent 2190 (DDpen, Kavo, Biberach, Alemanha) e câmera intraoral VistaProof (CI, Dürr Dental, Bietigheim-Bissingen, Alemanha), na detecção e na determinação da profundidade de lesões de cárie oclusais em molares decíduos, bem como
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17

Diller, Marie-Luce. "Détection, traitement du signal et modélisation de l'image de fluorescence in vitro et sur tissus biologiques : application au diagnostic des tumeurs cancéreuses par thérapie photodynamique, métrologie associée." Vandoeuvre-les-Nancy, INPL, 1994. http://www.theses.fr/1994INPL084N.

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L’aspect diagnostic en thérapie photodynamique repose sur la détection des cellules cancéreuses par l'utilisation d'un fluorophore. Le fluorophore le plus couramment utilisé est l'hématoporphyrine dérivée (HpD) ; il possède deux propriétés intéressantes: il se fixe préférentiellement sur les cellules cancéreuses et il émet une fluorescence rouge lorsqu'il est irradié par un rayonnement violet. La détection de cette fluorescence doit permettre la localisation de la tumeur. La présence d'une autofluorescence naturelle qui se superpose à la fluorescence induite et la mauvaise sélectivité du photo
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18

Minang, Jacob. "Cytokine responses in metal-induced allergic contact dermatitis : Relationship to in vivo responses and implication for in vitro diagnosis." Doctoral thesis, Stockholm : Dept. of Immunology, Wenner-Gren Institute, Stockholm University, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-717.

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19

Guermazi, Mahdi. "In-Vitro Biological Tissue State Monitoring based on Impedance Spectroscopy." Doctoral thesis, Universitätsbibliothek Chemnitz, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-206710.

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The relationship between post-mortem state and changes of biological tissue impedance has been investigated to serve as a basis for developing an in-vitro measurement method for monitoring the freshness of meat. The main challenges thereby are the reproducible measurement of the impedance of biological tissues and the classification method of their type and state. In order to realize reproducible tissue bio-impedance measurements, a suitable sensor taking into account the anisotropy of the biological tissue has been developed. It consists of cylindrical penetrating multi electrodes realizing g
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Diniz, Michele Baffi. "Detecção e avaliação da atividade de lesões de cárie primária e secundária em superfícies oclusais: Estudos in vitro e in vivo. /." Araraquara : [s.n.], 2010. http://hdl.handle.net/11449/104271.

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Resumo: O objetivo do presente estudo foi avaliar a efetividade de métodos empregados na detecção e na avaliação da atividade de lesões de cárie primárias e secundárias em superfícies oclusais de dentes decíduos e permanentes. Para tanto, foram realizadas quatro pesquisas. (1) O objetivo desta pesquisa foi avaliar in vitro a influência de métodos de profilaxia profissional nas medidas de fluorescência e no desempenho de três aparelhos baseados na captação da fluorescência induzida por luz na detecção de lesões de cárie oclusal em dentes permanentes. Os exames foram realizados em 110 dentes per
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21

Narušytė, Ingrida. "Preimplantacinės diagnostikos reguliavimas lyginamuoju aspektu." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2008. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2007~D_20080131_111543-64723.

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Šiame magistro baigiamajame darbe lyginamuoju metodu yra analizuojamas preimplantacinės diagnostikos reguliavimas įvairiose pasaulio valstybėse, tuo pačiu atskleidžiant pagrindines iš to kylančias problemas. Tyrimas atliktas siekiant palyginti skirtingų valstybių teisės aktus ir patirtį šioje biomedicinos srityje. Atlikta analizė rodo, kad preimplantacinė diagnostika vis dar yra pakankamai nauja ir atsargiai vertinama procedūra, sukelianti daug etinių ir teisinių diskusijų, o teisinis reguliavimas priklauso nuo valstybės teisinių, religinių, kultūrinių, socialinių tradicijų.<br>These master th
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Guermazi, Mahdi. "In-Vitro Biological Tissue State Monitoring based on Impedance Spectroscopy." Doctoral thesis, Universitätsverlag der Technischen Universität Chemnitz, 2016. https://monarch.qucosa.de/id/qucosa%3A20484.

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The relationship between post-mortem state and changes of biological tissue impedance has been investigated to serve as a basis for developing an in-vitro measurement method for monitoring the freshness of meat. The main challenges thereby are the reproducible measurement of the impedance of biological tissues and the classification method of their type and state. In order to realize reproducible tissue bio-impedance measurements, a suitable sensor taking into account the anisotropy of the biological tissue has been developed. It consists of cylindrical penetrating multi electrodes realizing
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Costa, Flávia Mesquita. "Produção de 18F-Fluorocolina no Centro de Desenvolvimento da Tecnologia Nuclear: síntese e estudos de citotoxicidade in vitro." CNEN - Centro de Desenvolvimento da Tecnologia Nuclear, Belo Horizonte, 2014. http://www.bdtd.cdtn.br//tde_busca/arquivo.php?codArquivo=336.

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A 18FCH é um biomarcador promissor para imagem de tumores usando a tecnologia PET, sendo eficaz no diagnóstico de tumores metastáticos e específico para tumores cerebrais, de próstata, de pulmão, entre outros. Apesar de já ser utilizada em alguns países como na França, Alemanha, Eslovênia, Polônia, România e Portugal, a 18FCH ainda não é produzida nem comercializada no Brasil. Este trabalho propôs o desenvolvimento de um novo radiofármaco baseado em colina marcada com o isótopo 18F para diagnóstico de imagens PET por ser uma demanda crescente na medicina nuclear nacional. Também foi proposto o
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Diniz, Michele Baffi [UNESP]. "Detecção e avaliação da atividade de lesões de cárie primária e secundária em superfícies oclusais: Estudos in vitro e in vivo." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/104271.

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Made available in DSpace on 2014-06-11T19:33:01Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-09-28Bitstream added on 2014-06-13T20:04:54Z : No. of bitstreams: 1 diniz_mb_dr_arafo.pdf: 6569673 bytes, checksum: be3c7e37c91460c335709d3c86d99dd1 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>O objetivo do presente estudo foi avaliar a efetividade de métodos empregados na detecção e na avaliação da atividade de lesões de cárie primárias e secundárias em superfícies oclusais de dentes decíduos e permanentes. Para tanto, foram realizadas quatro pesquisas.
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Bezerra, Ilana Sanamaika Queiroga 1984. "Influência do uso da ferramenta de redução do artefato no diagnóstico de fraturas radiculares verticais em exames de tomografia computadorizada de feixe cônico : estudo in vitro." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/290665.

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Orientadores: Deborah Queiroz de Freitas França, Gláucia Maria Bovi Ambrosano<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba<br>Made available in DSpace on 2018-08-26T13:33:44Z (GMT). No. of bitstreams: 1 Bezerra_IlanaSanamaikaQueiroga_D.pdf: 1698292 bytes, checksum: 997da55ad95075c898e9eae4519d6525 (MD5) Previous issue date: 2014<br>Resumo: O objetivo neste trabalho foi verificar a influência da ferramenta para redução de artefato (FRA) na qualidade da imagem e no diagnóstico de FRVs, em dentes com pino metálico intracanal. A amostra foi comp
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Cortial, Angèle. "Nouvelles applications des nanoparticules organiques : de la vectorisation d'un mélange d'actifs à travers la peau jusqu'au développement d'un test diagnostique in vitro de l'allergie aux parfums." Thesis, Lyon 1, 2015. http://www.theses.fr/2015LYO10018/document.

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Les nanoparticules (NPs) organiques représentent un outil majeur d'innovation en dermatologie. L'objectif de cette thèse a été de développer et d'optimiser des procédés d'encapsulation d'un mélange de molécules odorantes appelé fragrance mix I (FMI) dans des nanoparticules (NPs) de différentes natures: NPs polymères (poly-ε-caprolactone, PCL), ou NPs lipidiques solides (SLNs) (à base de vaseline, beurre de karité, cire de candelilla, triglycérides C10-18, ou palmitate de cétyle). Ces nouveaux systèmes ont alors été évalués pour la vectorisation de ce mélange à travers un explant de peau de por
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Bammesberger, Stefan Borja [Verfasser], and Roland [Akademischer Betreuer] Zengerle. "A smart reagent dosing cartridge for in-vitro diagnostics = Eine intelligente Dosierkartusche für die in-vitro Diagnostik." Freiburg : Universität, 2014. http://d-nb.info/1123481032/34.

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Liwa, Anthony Cuthbert. "Pharmacokinetics and dosing rationale of Para-Aminosalicylic acid in children and the evaluation of the in vitro metabolism of Ethionamide, Terizidone and Para-aminosalicylic acid." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/20165.

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Thesis (MScMedSc)--Stellenbosch University, 2012.<br>ENGLISH ABSTRACT: BACKGROUND: The emergence of mycobacterium tuberculosis resistance to first line drugs has renewed interest in second-line anti-tuberculosis drugs. Generally, Paraaminosalicylic acid (PAS) is less potent and frequently more toxic than the first line drugs. Furthermore, the pharmacokinetics of PAS in children has not been well characterized. AIMS: The aims of the present study were (1) to determine the pharmacokinetics of PAS in pediatric patients, (2) to describe the discrepancy between children and adult pharmacoki
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Janer, Eleonor Adega Castro. "Resistência de Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) a fipronil: Padronização de bioensaios in vitro, detecção de resistência em populações de campo e avaliação sobre resistência cruzada com outras drogas." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/42/42135/tde-17012011-113819/.

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Para o sucesso das estratégias de manejo de Rhipicephalus (Boophilus) microplus (carrapato bovino) são necessários testes práticos, econômicos e confiáveis que possam detectar a presença de fenótipos resistentes a drogas em suas populações. O fipronil é um acaricida de uso relativamente recente não havendo testes padronizados para o diagnóstico de resistência do carrapato à molécula. No presente trabalho, foram padronizados bioensaios in vitro para esta finalidade: Teste de Imersão de Adultas, Teste de Imersão de Larvas e Teste de Pacote com Larvas. Os testes foram aplicados e, de forma inédit
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Eduardo, Fernanda de Paula. "Eduardo FP. Análise in vitro da fototerapia com lasers em baixa intensidade (660 nm e 780 nm) sobre a ação do vírus herpes tipo I em células epiteliais de macacos (Vero) [Tese de Doutorado]. São Paulo: Faculdade de Odontologia da USP; 2006. RESUMO." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/23/23139/tde-02062006-094935/.

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A fototerapia com lasers em baixa intensidade de lesões de herpes simples tem sido demonstrada clinicamente ora prevenindo a formação de vesículas, ora cicatrizando rapidamente as lesões e até aumentando o espaço de tempo entre o aparecimento dessas manifestações recorrentes. No entanto, os mecanismos básicos de ação dos lasers nessas situações são desconhecidos. Dessa forma, o objetivo do trabalho foi realizar ensaios in vitro utilizando células epiteliais em cultivo e culturas do vírus HSV-1 para estudar a interferência do laser em baixa intensidade na infecção do HSV-1. Material e Métodos:
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Bernt, Andreas. "In-vitro Diagnostik der Nase." Diss., Ludwig-Maximilians-Universität München, 2014. http://nbn-resolving.de/urn:nbn:de:bvb:19-178411.

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Niemimaa, M. (Marko). "First trimester screening for Down syndrome." Doctoral thesis, University of Oulu, 2003. http://urn.fi/urn:isbn:9514270290.

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Abstract The aim of the present study was to evaluate the efficacy of the first trimester screening for Down syndrome (DS) in an unselected low-risk Finnish population. The study involved 4,617 women who attended screening between the 8th and 14th weeks of pregnancy in 1998-2000. They gave a blood sample for the measurement of pregnancy associated plasma protein A (PAPP-A) and free beta human chorionic gonadotrophin (β-hCG). Of these women, 3,178 also had an ultrasound examination for the measurement of fetal nuchal translucency (NT). The risk figure for every screened woman was calculated usi
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Pai͏̈s-Becher, Carole. "Le diagnostic préimplantatoire." Paris 5, 1996. http://www.theses.fr/1996PA05P057.

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Tararbit, Karim. "Assistance médicale à la procréation et cardiopathies congénitales : études en population." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA11T024/document.

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A partir de données en population, nous avons: 1) évalué le risque de cardiopathies congénitales (CC) chez les fœtus conçus par assistance médicale à la procréation (AMP); et 2) déterminé les effets de l’AMP sur la prise en charge prénatale et le devenir périnatal des fœtus porteurs de CC. Nous avons observé que l'AMP était associée à une augmentation de 40% du risque de CC sans anomalies chromosomiques associées (OR ajusté = 1,4 IC95% 1,1-1,7). Nous avons également retrouvé qu'il existait des associations variables selon la catégorie de CC et la méthode d'AMP considérées. Nous avons observé q
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Nolting, Andreas. "Companion Diagnostics Development and Commercialization : A Case Study from the Diagnostics’ Perspective." Thesis, KTH, Hållbarhet och industriell dynamik, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-170181.

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The value proposition of Personalized Medicine is to deliver the “right drug, to the right patient, at the right time”. Companion diagnostics is the required tool for Personalized Medicine used to aid clinical decision making with the aim to identify patients who are most suitable for a given treatment approach and to avoid adverse effects. However, even 16 years after the first co-approval of a therapeutic drug and an associated diagnostic test (trastuzumab (Herceptin1) from Genentech and the HercepTest1 from Dako), the co-development and co-approval of drug-diagnostic pairs is a challenging
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36

Bignami, Adrian (Adrian A. ). "Economic potential for clinically significant in vitro diagnostics." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/54672.

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Thesis (S.M.)--Harvard-MIT Division of Health Sciences and Technology, 2009.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (p. 53-56).<br>In recent years, significant advances have been made in the realm of in vitro diagnostics with the development of novel tests which are able to meaningfully impact the course of a patients' disease management. This transformation has strained the traditional in vitro diagnostic business model and raised questions as to whether the economics support the commercial development of these tests. The goal of this study is to evalu
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Blaire, Guillaume. "Test d'immunodiagnostic innovant combinant nanoparticules superparamagnétiques et micro-aimants." Thesis, Grenoble, 2014. http://www.theses.fr/2014GRENT116.

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Les micro et nanoparticules magnétiques sont de plus en plus utilisées en biologie et en médecine, pour une large gamme d'applications. Plusieurs applications utilisent le piégeage et le guidage de ces billes sous l'effet d'un champ et d'un gradient de champ magnétique. Dans la plupart des applications, le champ magnétique est macroscopique, créé par un aimant ou un électro-aimant. L'intégration plus poussée est souvent envisagée, dans les articles scientifiques, par des microbobines ou par des éléments magnétiques doux. Ceux-ci doivent alors être polarisés par un champ externe (de nouveau, un
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Bini, Andressa Peres. "Estudo molecular do desenvolvimento de Puccinia psidii Winter in vitro e no processo de infecção em Eucalyptus grandis." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/11/11137/tde-10112016-161846/.

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O Brasil é um dos principais produtores mundiais de Eucalyptus spp., mas a produção dessa cultura tem sido comprometida por perdas causadas pelo fungo Puccinia psidii Winter, agente causal da ferrugem do eucalipto. Compreender os mecanismos moleculares da patogenicidade desse fungo, conhecer a composição química de variedades de Eucalyptus spp. resistentes e suscetíveis ao fitopatógeno e ter em mãos uma ferramenta de diagnóstico precoce da doença são conhecimentos de fundamental importância para o desenvolvimento de estratégias de controle do fitopatógeno. Uma das principais barreiras que limi
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Buick, Stephanie Fiona. "Development of an in vitro diagnostic technique for Malassezia furfur." Thesis, University of Canterbury. Microbiology, 1997. http://hdl.handle.net/10092/7053.

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Malasseziafurfur (synonym Pitryosporum ovale) is a dimorphic, lipophilic yeast that is a commensal agent on human skin. M. furfur causes the skin conditions pityriasis versicolor, Malassezia folliculitits and seborrhoeic dermatitis. It also contaminate catheters supplying lipid emulsion which can led to pulmonary infections or septicaemia. Due to the increasing number of immunocompromised patients, the frequency and severity of M. furfur is escalating. Difficulty in culture is due to limited knowledge about the nutrient requirements of M. furfur, which leads to erroneous diagnosis and incorrec
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40

Sung, Ki-Joo. "Engineering non-immunoglobulin binding proteins for in vitro diagnostic Tests." Thesis, Massachusetts Institute of Technology, 2020. https://hdl.handle.net/1721.1/130192.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, May, 2020<br>Includes bibliographical references.<br>In 2016, nearly 5.5 million deaths were attributed to infectious and parasitic diseases. Although many of these diseases are preventable and treatable, resource-constrained regions often lack access to rapid and accurate diagnostic tests to appropriately diagnose and treat these diseases. In order to improve the accessibility of diagnostics, the development of low-cost, simple, and rapid diagnostic tests is vital. Antibodies have been widely used as th
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41

Vervier, Kevin. "Méthodes d’apprentissage structuré pour la microbiologie : spectrométrie de masse et séquençage haut-débit." Thesis, Paris, ENMP, 2015. http://www.theses.fr/2015ENMP0081/document.

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L'utilisation des technologies haut débit est en train de changer aussi bien les pratiques que le paysage scientifique en microbiologie. D'une part la spectrométrie de masse a d'ores et déjà fait son entrée avec succès dans les laboratoires de microbiologie clinique. D'autre part, l'avancée spectaculaire des technologies de séquençage au cours des dix dernières années permet désormais à moindre coût et dans un temps raisonnable de caractériser la diversité microbienne au sein d'échantillons cliniques complexes. Aussi ces deux technologies sont pressenties comme les piliers de futures solutions
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42

Bisceglia, Émilie. "Méthodes physiques d’extraction de micro-organismes à partir d’échantillons sanguins à l'aide de microsystèmes." Thesis, Cachan, Ecole normale supérieure, 2013. http://www.theses.fr/2013DENS0042/document.

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Dans le domaine du diagnostic in vitro, l'étape d'extraction de micro-organismes à partir d'un échantillon complexe est une étape clé pour permettre l'identification du pathogène responsable d'une infection. Pour les septicémies, cette étape d'extraction est généralement précédée d'une étape de culture, ce qui conduit à une obtention des résultats au bout de plusieurs jours. Un résultat plus rapide (typiquement inférieur à 24h) permettrait d'augmenter le taux de survie des patients, et aurait ainsi une forte valeur ajoutée pour le corps médical. Le but de ces travaux est donc de développer une
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43

Kemp-Harper, Richard Owen. "Development of multiple-pulse NMR methods for investigation of sodium ions in vitro." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.339303.

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44

Svernsjö, Robert. "Patientnära analyser för in vitro-diagnostik inom prehospital akutsjukvård En litteraturstudie." Thesis, Mittuniversitetet, Avdelningen för omvårdnad, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-33729.

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Kemp, Roger. "Developing a competitive strategy for the in vitro cancer diagnostics industry /." Burnaby B.C. : Simon Fraser University, 2005. http://ir.lib.sfu.ca/handle/1892/3669.

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46

Fike, Kate E. "DEVELOPMENT AND COMMERCIALIZATION OF CIRCULATING FETAL CELL BASED TECHNOLOGY AS A NON-INVASIVE PRENATAL DIAGNOSTIC TOOL." Case Western Reserve University School of Graduate Studies / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=case1621460632878665.

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Leetz, Anna Susanne. "Ein Beitrag zur molekularen Diagnostik und Entwicklungsbiologie von Cryptosporidium parvum in vitro /." Köln, 2009. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000278349.

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Peelukhana, Srikara Vishwanath. "Effect of coronary collateral flow on diagnostic parameters: An In vitro study." University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1258473630.

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49

Bernt, Andreas [Verfasser]. "In-vitro Diagnostik der Nase. Ein Methodenvergleich anhand chronisch nasaler Erkrankungen / Andreas Bernt." München : Verlag Dr. Hut, 2014. http://d-nb.info/1064560067/34.

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Shi, Song. "Screening anti-prion compounds and diagnosing prion diseases by amplifying PrPSc in vitro." Diss., Ludwig-Maximilians-Universität München, 2015. http://nbn-resolving.de/urn:nbn:de:bvb:19-179963.

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