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Dissertations / Theses on the topic 'Diagnostic Advancements'

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1

Usoltceva, Mariia. "Advancements in Langmuir probe diagnostic for measurements in RF sheath and in modelling of the ICRF slow wave." Electronic Thesis or Diss., Université de Lorraine, 2019. http://www.theses.fr/2019LORR0061.

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Injecter de la puissance au plasma avec les ondes au voisinage de la fréquence cyclotron ionique (ICRF) est une technique prometteuse pour chauffer les plasmas de tokamak aux températures de fusion requises. Pour le rendement élevé, l'antenne ICRF doit être placée à proximité du plasma, mais ils accroissent les interactions plasma-paroi néfastes. Les ions accélérés par le champ électrique dans la gaine radiofréquence (RF) se sont avérés être à l'origine de ces interactions. La conception de l'antenne ICRF pourrait être optimisée pour réduire les effets observés. Ces études peuvent être réalisé
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2

Pauff, Steven M. "Advancements in the Synthesis and Application of Near-Infrared Imaging Reagents: A Dissertation." eScholarship@UMMS, 2015. https://escholarship.umassmed.edu/gsbs_diss/751.

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Fluorescence-based imaging techniques provide a simple, highly sensitive method of studying live cells and whole organisms in real time. Without question, fluorophores such as GFP, fluorescein, and rhodamines have contributed vastly to our understanding of both cell biology and biochemistry. However, most of the fluorescent molecules currently utilized suffer from one major drawback, the use of visible light. Due to cellular autofluorescence and the absorbance of incident light by cellular components, fluorescence imaging with visible wavelength fluorophores often results in high background no
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3

Pauff, Steven M. "Advancements in the Synthesis and Application of Near-Infrared Imaging Reagents: A Dissertation." eScholarship@UMMS, 2001. http://escholarship.umassmed.edu/gsbs_diss/751.

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Fluorescence-based imaging techniques provide a simple, highly sensitive method of studying live cells and whole organisms in real time. Without question, fluorophores such as GFP, fluorescein, and rhodamines have contributed vastly to our understanding of both cell biology and biochemistry. However, most of the fluorescent molecules currently utilized suffer from one major drawback, the use of visible light. Due to cellular autofluorescence and the absorbance of incident light by cellular components, fluorescence imaging with visible wavelength fluorophores often results in high background no
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4

Hicks, Debbie. "Investigating opportunities for diagnostic and therapeutic advancement in the collagen vi-related disorders." Thesis, University of Newcastle Upon Tyne, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500962.

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Mutations in C0L6A], COL6A2 and COL6A3, the genes which encode the extracellular matrix component collagen VI, lead to Bethlem myopathy BM Ullrich Congenital Muscular Dystrophy (UCMD) and myosclerosis myopathy. Unlike UCMD, BM is difficult to diagnose due to its clinical overlap with other contractural phenotypes and the lack of sensitivity of standard immunohistochemica! diagnostic techniques in muscle biopsy samples. This thesis investigates the potential of two prospective diagnostic techniques, and proposes an algorithm for better BM diagnosis based on immunofluorescent labelling of collag
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5

Bresolin, Silvia. "Advancements in Molecular Prognostics and Diagnostics of Pediatric Myelodysplastic Syndrome and Juvenile Myelomonocytic Leukemia." Doctoral thesis, Università degli studi di Padova, 2012. http://hdl.handle.net/11577/3422195.

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Myelodysplastic syndromes (MDS) and juvenile myelomonocytic leukemia (JMML) are rare hematopoietic stem cell diseases constituting less then 5% of hematopoietic neoplasia in childhood. Pediatric MDS is an heterogeneous groups of disorders with ineffective hematopoiesis and a varying propensity to evolve into acute myeloid leukemia (AML). Juvenile myelomonocytic leukemia (JMML) is a very aggressive myeloproliferative/ myelodysplastic disease characterized by excessive proliferation of granulocytic and monocytic cells and classified by the World Health Organization (WHO) as a separate entity bet
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6

Rahman, Brian M. "Sensor Placement for Diagnosis of Large-Scale, Complex Systems: Advancement of Structural Methods." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1562859497638274.

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7

Blignaut, Anel. "Prediction of the efficacy of a mandibular advancement splint in the treatment of obstructive sleep apnea using various diagnostic methods." Thesis, Faculty of Dentistry, 2015. http://hdl.handle.net/2123/13451.

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8

Mohammadieh, Anna Mary. "Enhancing the Diagnosis and Management of Obstructive Sleep Apnoea in Atrial Fibrillation Patients." Thesis, The University of Sydney, 2022. https://hdl.handle.net/2123/29879.

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Background: Atrial fibrillation (AF), is the most common sustained cardiac arrhythmia, and significantly increases the risk of stroke and cardiovascular mortality. It is strongly associated with obstructive sleep apnoea (OSA). Aims: 1. Examine the epidemiology of OSA in a hospital cohort with AF. 2. Compare the diagnostic accuracy of clinical screening tools for OSA in patients with AF. 3. Compare cardiac autonomic function in AF patients with and without OSA. 4. Conduct a pilot study of mandibular advancement splint (MAS) therapy for OSA in AF patients. Methods: 107 AF patients were re
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9

Rogers, Craig David. "Ecological and molecular investigation of wheat bulb fly (Delia coarctata, Fallén, Diptera : Anthomyiidae) for the advancement of population monitoring and control methodologies." Thesis, University of Edinburgh, 2012. http://hdl.handle.net/1842/6267.

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Wheat bulb fly (WBF) (Delia coarctata, Fallén, Diptera: Anthomyiidae) is a pest of commercial importance in cereal crops. Control is dependent on organophosphates some of which are restricted in the UK, while current oviposition monitoring techniques are labour intensive and subjective. Eggs are not laid in association with a host-plant, therefore, prompt location of a suitable host is critical to the survival of the newly hatched larvae. Wheat bulb fly larvae have been shown to exhibit a positive chemotactic response to wheat and other host-plant seedlings and their root exudates. The object
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10

Gustafsson, Ulla-Maria. "Anal Fistula : Aspects of Aetiology, Diagnosis and Prognosis After Surgical Treatment." Doctoral thesis, Uppsala University, Department of Surgical Sciences, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7831.

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<p>Patients with idiopathic anal fistula (n=85) were compared with 215 control subjects, matched for age and sex, through a 180-item questionnaire. Obesity, smoking, constipation and bowel symptoms associated with IBS were more common in the patients.</p><p>Endoanal ultrasound (EUS) and magnetic resonance imaging (MRI) were compared in the preoperative evaluation of anal fistula in 23 patients. For classifying the primary tract, EUS and surgical findings agreed in 14 cases, and MRI and surgery for 11: for identifying an internal opening, the corresponding figures were 17 and 10.</p><p>Healing
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11

Culpan, Gary, and Bryan McIntosh. "Optimising diagnostics through imaging informatics: Costs and opportunities." 2017. http://hdl.handle.net/10454/12683.

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Yes<br>Increasing diagnostic capacity is a national priority to expedite the timeliness and appropriateness of patient treatment interventions. Imaging—encompassing a range of technologies including X-ray, CT, MRI, nuclear medicine and ultrasound—is a key diagnostic service and central to decision-making in most, if not all, disease pathways. However, imaging is an expensive discipline accounting for an estimated 3–5% of the annual NHS budget. As a result, it is imperative that we maximise service efficiency while optimising patient outcomes.<br>The manuscript version differs from the publishe
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12

Braff, Dana. "Technological advancements towards paper-based biomolecular diagnostics." Thesis, 2017. https://hdl.handle.net/2144/27009.

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Clinically tractable diagnostics must be low-cost, rapid, sensitive, easy to use, and adaptable to new targets. With its rational design, synthetic biology holds promise for developing diagnostic technologies that can address these needs. In particular, progress in synthetic biology has led to improved circuit-building abilities and a large collection of biomolecular sensors. However, these technologies fundamentally require transcription and translation, limiting their applicability to cellular contexts In vitro cell-free expression systems that contain transcription and translation machiner
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13

Legendre, Lindsay Ann. "Advancements in totally integrated microdevices for clinical diagnostics /." 2007. http://wwwlib.umi.com/dissertations/fullcit/3282505.

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14

(9515840), Jordan Matthew Fisher. "Advancements and Practical Applications of Molecular Tagging Velocimetry in Hypersonic Flows." Thesis, 2020.

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<div>Hypersonic flows consist of harsh environments where chemistry effects are relevant and low speed assumptions such as the ideal gas law and the continuum hypothesis</div><div>begin to break down. Because of these processes, computer models do a poor job of predicting behavior of vehicles in hypersonic flight. High fi?delity ground test</div><div>measurements are necessary to anchor and extrapolate CFD simulations so that flight vehicle designs can continue to improve. Due to the harsh conditions and complexities</div><div>of test facilities, implementing experimental measurements can prov
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(6560621), Brittani Lynn Bungart. "DEVICE AND IMAGE ANALYSIS ADVANCEMENTS TOWARDS PHOTOACOUSTIC AND ULTRASOUND TOMOGRAPHY-GUIDED PROSTATE BIOPSY." Thesis, 2019.

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To confirm the presence of prostate cancer which is the most incident visceral cancer in men, prostate biopsies are acquired using the magnetic resonance imaging fusion-guided prostate biopsy protocol. For this approach annotated magnetic resonance imaging is overlaid onto real-time ultrasound imaging to guide sampling of suspicious regions marked by uroradiologists. Additional biopsy samples are acquired via the previous clinical gold standard, i.e. the templated 12-core transrectal ultrasound-guided prostate biopsy protocol. While this approach improves the sensitivity of the prostate biopsy
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