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Dissertations / Theses on the topic 'Diagnostic meningit'

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1

Троцька, Ірина Олександрівна, Ирина Александровна Троцкая, Iryna Oleksandrivna Trotska та Н. В. Дем`яненко. "Клінічні критерії діагностики менінгітів на догоспітальному етапі". Thesis, Видавництво СумДУ, 2008. http://essuir.sumdu.edu.ua/handle/123456789/3719.

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2

Wessels, Marie. "Clinical value of a uniform research case definition of tuberculous meningitis." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/86775.

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Thesis (MMed)--Stellenbosch University, 2014.<br>ENGLISH ABSTRACT: BACKGROUND: Tuberculous meningitis (TBM) research remains important but obtaining adequate sample sizes of microbiologically-confirmed TBM cases is difficult, therefore clinical cases of TBM need to be included. A uniform research case definition for TBM was developed to assist diagnostic standardization. METHODS: Our study evaluated the proposed uniform research case definition in a group of children diagnosed with TBM. A subgroup of 66 children with cultureconfirmed TBM was compared to culture-confirmed bacterial mening
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3

Atobe, Jane Harumi. "Amplificação de DNA de Neisseria meningitidis em amostras de líquido cefalorraquidiano pela reação em cadeia da polimerase-multiplex." Universidade de São Paulo, 1998. http://www.teses.usp.br/teses/disponiveis/9/9136/tde-11082006-115017/.

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Padronizou-se a PCR-Multiplex para a detecção do DNA de Neisseria meningitidis. Para tanto os primers escolhidos foram: RW01, DG74 e COR28 baseados na subunidade menor do ribossomo (16S rRNA) que apresenta regiões de seqüências conservadas encontradas em todas as bactérias conhecidas. Os primers RW01 e DG74 amplificaram o fragmento universal bacteriano de 370 bp e, os primers RW01 e COR28, o fragmento específico de N. meningitidis de 279 bp em uma única etapa. Os resultados obtidos nas amostras de LCR de 168 pacientes pelos métodos de cultura e PCR-Multiplex quando comparados à bacterioscopia
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4

Moatti, Catherine. "Intérêt du dosage intrathécal de l'interféron alpha dans le diagnostic étiologique des méningites." Paris 5, 1991. http://www.theses.fr/1991PA05P099.

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5

DELFORGE, FRANCOIS. "Interet du dosage de l'interferon alpha dans le diagnostic des meningoencephalites et meningites virales." Lille 2, 1989. http://www.theses.fr/1989LIL2M122.

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6

Dele-Ijagbulu, Kemi Dorcas. "The aetiologies, clinical presentation, diagnostic difficulties and outcomes of meningitis among HIV-positive adults admitted to Livingstone hospital, Port Elizabeth." University of Western Cape, 2019. http://hdl.handle.net/11394/7659.

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Master of Public Health - MPH<br>Meningitis is a common opportunistic infection and an important cause of mortality among people living with HIV and AIDS globally. This study investigated meningitis in adults living with HIV and AIDS admitted to the medical wards of Livingstone tertiary hospital in Port Elizabeth in 2018 and determined the prevalence of its aetiological types, clinical presentations, diagnostic challenges, treatment outcomes and predictors of prognosis.
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7

Caws, Maxine Anna Maria. "The diagnosis and immunogenetics of tuberculous meningitis." Thesis, King's College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271415.

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8

Lunardi, Luciano Werle. "Uso do índice de celularidade no líquor para diagnóstico precoce de infecção no sistema nervoso central após drenagem ventricular externa." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/164831.

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O uso de Derivação Ventricular Externa (DVE) é necessário para o tratamento de muitas doenças, como Traumatismo Cranioencefálico (TCE) e Hemorragia Subaracnoide (HSA). As meningites e ventriculites são complicações frequentes desse uso. Neste trabalho buscamos determinar sensibilidade, especificidade e ponto de corte para o Índice de Celularidade (IC) em pacientes com TCE, HSA e acidente vascular cerebral hemorrágico (AVCh). Nossa população de estudo foi composta por pacientes com diferentes doenças de base e poucos resultados de cultura de líquor positiva. Para diagnóstico das infecções foram
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9

McGill, F. J. "Improving the diagnosis of meningitis in UK adults." Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3005772/.

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10

BILLIOTTE, ANNE. "Apport de la microbiologie au diagnostic etiologique des meningites : a propos des observations du service des maladies infectieuses du c.h.u. de marseille hopital de la conception." Aix-Marseille 2, 1992. http://www.theses.fr/1992AIX20066.

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11

Etcheverry, Philippe. "Diagnostic manométrique de l'hydrocéphalie aigue͏̈ après hémorragie méningée." Bordeaux 2, 1989. http://www.theses.fr/1989BOR25A74.

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12

Abués, Mohanna Damasceno. "Perfil etiológico da meningite bacteriana no estado do Tocantins." Universidade Federal do Tocantins, 2018. http://hdl.handle.net/11612/1026.

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A meningite bacteriana continua sendo um problema de saúde pública no Brasil, estudá-la em todos seus aspectos faz com que as chances de intervenções possam ser descobertas a fim de diminuir seus altos índices de mortalidade e sequelas dentre as pessoas acometidas. O presente trabalho teve por finalidade caracterizar o perfil etiológico da meningite bacteriana no estado do Tocantins, no período de 2010 a 2017, através de um estudo retrospectivo, transversal, de natureza quantitativa, realizado a partir de dados provenientes do Laboratório Central de Saúde Pública do Estado do Tocantins (
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13

Thwaites, Edward. "The diagnosis and pathophysiology of tuberculosis meningitis in Vietnamese adults." Thesis, Open University, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406488.

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14

Sokhan, A. V. "Neurospecific markers - new opportunities in the diagnosis of bacterial meningitis." Thesis, Sumy State University, 2017. http://essuir.sumdu.edu.ua/handle/123456789/64505.

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У роботі представлені результати дослідження рівнів нейроспецифічних маркерів NSE, протеїну S-100, GFAP та MBP у цереброспінальній рідині хворих на менінгококовий та пневмококовий менінгіти в динаміці хвороби. Визначено наявність уражень нейронів, астрогліальних клітин та мієлінових нервів у всіх хворих та визначена можливість використання цих показників з діагностичною та прогностичною метою.<br>Diagnostic role of neuro specific proteins in assessing the degree of damage to the cells of the central nervous system currently confirmed. It proved that levels of neuron specific proteins
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15

Corless, Caroline Elizabeth. "Non-culture diagnosis and case ascertainment of meningitis and septicaemia." Thesis, Manchester Metropolitan University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269153.

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16

Santos, Daniela Carvalho dos. "Estabelecimento de métodos moleculares para aplicação no diagnóstico rápido de virus neurotrópicos." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-02122009-110053/.

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Diversos agentes virais são causadores de meningites e meningoencefalites. Neste estudo, técnicas moleculares foram utilizadas para detecção de HEV, HHV e HAdV em amostras de líquor colhidas de janeiro de 2005 a março de 2007. Dos três métodos de extração de DNA e RNA testados, o kit DNA Qiablood Qiagen® se mostrou o mais sensível e específico. A nested PCR detectou HEV em 28% das amostras, HSV em 4%, HHV-3 em 1%; HHV-4 em 0,3%, HHV-5 em 0,3%, HHV-6 em 0,7% e HAdV em 13%. Através da PCR em tempo real os HEV foram detectados em 23,3% e HSV em 5,1%. Por neutralização, somente duas amostras fora
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17

Heemskerk, Anna Dorothee. "Tuberculous meningitis : reducing the burden of disease by improving diagnosis and treatment." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:f2f9b2cf-9df0-4956-abb8-1cada367b7ad.

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Notwithstanding available diagnosis and treatment, tuberculosis (TB) is the most persistent pandemic known to modern man. Of all forms of tuberculosis, tuberculous meningitis (TBM) is the most lethal. The true burden of disease is unknown, but of the people who reach treatment facilities, approximately 30% die, despite therapy. The onset of disease is insidious and diagnosis is often only made after neurological compromise, a factor associated with increased mortality. Diagnosis is further complicated by lack of sensitivity of currently available conventional microbiological techniques. Moreov
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18

GUFFOND, THIERRY. "Valeurs et limites de la p. C. R. Dans le diagnostic presomptif des meningo-encephalites herpetiques." Lille 2, 1993. http://www.theses.fr/1993LIL2P005.

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19

Puech, Eric. "Diagnostic biologique des infections du systeme nerveux central d'origine herpetique ou zosterienne chez l'adulte : interet du rapport des igg specifiques, du lcr et du serum : a propos de 169 dossiers." Saint-Etienne, 1988. http://www.theses.fr/1988STET6061.

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20

Abdullah, Gadija. "The detection of meningococcal disease through identification of antimicrobial peptides using an in silico model creation." University of the Western Cape, 2019. http://hdl.handle.net/11394/7079.

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Philosophiae Doctor - PhD<br>Neisseria meningitidis (the meningococcus), the causative agent of meningococcal disease (MD) was identified in 1887 and despite effective antibiotics and partially effective vaccines, Neisseria meningitidis (N. meningitidis) is the leading cause worldwide of meningitis and rapidly fatal sepsis usually in otherwise healthy individuals. Over 500 000 meningococcal cases occur every year. These numbers have made bacterial meningitis a top ten infectious cause of death worldwide. MD primarily affects children under 5 years of age, although in epidemic outbreaks there i
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21

Gualberto, Felipe Augusto Souza. "Valor disgnóstico da nested PCR em tempo real em pacientes com meningite tuberculosa." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5134/tde-26082014-093325/.

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Introdução: A meningite tuberculosa (MTB) é a forma mais grave e fatal de tuberculose. O diagnóstico oportuno e o tratamento adequado e precoce são os principais fatores associados com o bom prognóstico. Os métodos utilizados na prática médica diária - achados clínicos, exames de imagem e análise de líquido cefalorraquidiano (LCR) - têm baixa acurácia. A pesquisa do DNA do Mycobacterium tuberculosis no LCR através da reação em cadeia da polimerase (PCR, do inglês polimerase chain reaction) com a metodologia nested é promissora, especialmente quando associada à praticidade da amplificação do DN
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22

Chhaganlal, Kajal [Verfasser], and Florian [Akademischer Betreuer] Heinen. "Diagnosis and differential diagnosis of meningitis at patient's bed side using urine reagent strip to evaluate cerebro spinal fluid / Kajal Chhaganlal. Betreuer: Florian Heinen." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2014. http://d-nb.info/109451702X/34.

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23

Swanepoel, Hendré. "Utility of chloride and adenosine deaminase measurement in cerebrosphinal fluid for the early presumptive diagnosis of tuberculous meningitis." Master's thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/25438.

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Background: Chloride and adenosine deaminase measurements in cerebrospinal fluid are still sporadically requested as part of tuberculous meningitis work-up. In the literature, evidence is contradictory and opinion is divided on their utility in clinical practice. The accuracy of both for the early presumptive diagnosis of tuberculous meningitis was investigated in patients in a region with high prevalence of tuberculosis and HIV infection in order to inform a decision on whether to continue offering these tests to clinicians. Methods: A retrospective descriptive study of diagnostic accuracy wa
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24

Andronikou, Savvas. "High density exudates and basal meningeal enhancement in computed tomography of the head in the diagnosis of paediatric tuberculous meningitis." Doctoral thesis, University of Cape Town, 2005. http://hdl.handle.net/11427/2853.

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25

Temfack, Elvis. "Epidemiology and optimal management of cryptococcal meningo-encephalitis associated with AIDS in Cameroon." Thesis, Sorbonne Paris Cité, 2017. http://www.theses.fr/2017USPCB049/document.

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Pas de résumé<br>Cryptococcal meningitis (CM), caused by an encapsulated yeast is a leading cause of AIDS related opportunistic infection in adults in sub-Saharan Africa and a major driver of mortality, second to tuberculosis. We aimed at optimising the management of AIDS-related cryptococcal meningitis in Cameroon through interventional studies. As such, we designed and performed three studies on the role of cryptococcal antigen (CrAg) in CM diagnosis, contributed in a major phase III non-inferiority clinical trial for inductive treatment of CM in the African setting and analysed the trial pa
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26

Deschamps, Martine. "Apports de la tomographie d'émission monophotonique (TEM) par 99mTc-HMPAO à l'évaluation hémodynamique périopératoire des hémorragies méningées par rupture d'anévrysme." Montpellier 1, 1991. http://www.theses.fr/1991MON11042.

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27

Khumalo, Jermaine. "The use of molecular diagnostic methods to improve the detection of the common bacterial and viral causes of community acquired meningitis in children in South Africa." Master's thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/15539.

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With conventional methods of diagnosis, substantial overlaps are common due to an absence of the expected CSF findings clearly aligning to bacterial or viral infection. Reduced sensitivity is commonly observed chiefly due to empiric antibiotic treatment leading to bacterial culture negative results. This leads to costly hospital admissions and unnecessarily prolonged treatment for the unexplained aetiology, further compounded by routine viral diagnostics not being commonly implemented for meningitis diagnosis. We developed and validated in-house quantitative real-time (qPCR) multiplex assays t
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FAVARO, MARCO. "Studio di una PCR multitarget in real time PCR per la diagnosi rapida di meningite: ipotesi di studio per l'applicazione di un nuovo tipo di sonda molecolare." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2010. http://hdl.handle.net/2108/1206.

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La meningite è un'infiammazione delle meningi, le membrane che rivestono il cervello e il midollo spinale. Di solito è causata da batteri o virus, ma può anche essere causato da farmaci o malattie (meningite di eziologia non infettiva). La meningite batterica è rara, ma di solito è grave e può essere pericolosa per la vita se non trattata immediatamente. La meningite virale (detta anche meningite asettica) è relativamente comune e molto meno grave. Rimane spesso non diagnosticata perché i suoi sintomi possono essere simili a quelli della comune influenza. Se tempestivamente diagnosticata, la m
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Haddar, Cyrille Hedi. "Développement et évaluation de tests antigéniques rapides pour le diagnostic d’infections méningococciques et pneumococciques." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSES065.

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Les tests de diagnostic rapide (TDR) sont aujourd’hui des outils indispensables pour une réponse urgente en pathologie infectieuse. De nombreux tests sont disponibles pour rechercher différents agents pathogènes (VIH, streptocoque du groupe A, plasmodium …) dans des prélèvements biologiques variés (urine, liquide cérébrospinal ou LCS, sang …). L’avantage de ce mode de diagnostic est leur rapidité, leur simplicité de mise en œuvre, y compris par des non-spécialistes ou à l’extérieur d’une structure de laboratoire, et leur coût raisonnable. Dans ce travail de thèse CIFRE, nous présentons trois T
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30

Von, Pressentin Klaus Botho. "A Medical audit of the management of cryptococcal meningitis in HIV patients in the Cape Winelands (East) district, Western Cape, South Africa." Stellenbosch : Stellenbosch University, 2010. http://hdl.handle.net/10019.1/37562.

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Stellenbosch University. Faculty of Medicine and Health Sciences. Interdisciplinary Health Sciences. Family Medicine and Primary Care.<br>Thesis (MFamMed) -- Stellenbosch University, 2010.<br>Bibliography<br>ENGLISH ABSTRACT: Introduction: This thesis summarises the findings of a medical audit on the management of Cryptococcal Meningitis (CM). The study population of HIV positive adults (N = twenty five) were admitted during November 2009 – June 2010 to five hospitals of the Cape Winelands (East) District, Western Cape, South Africa. In the context of the HIV pandemic, CM has become the most
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31

Guedj, Romain. "Risque d'urgence neurologique grave et curable parmi les enfants présentant une crise d'épilepsie en contexte fébrile : un exemple d'utilisation des dossiers médicaux informatisés des urgences pour la recherche clinique." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066005/document.

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Entre 2 et 5% des enfants de 6 mois à 5 ans présentent au moins un épisode de Crise d’Épilepsie en contexte Fébrile (CEF). Bien que généralement bénignes, ces crises sont associées à un risque d’urgences neurologiques graves et curables dont l’élimination requiert la réalisation d’examens complémentaires douloureux et/ou irradiants. Actuellement, ce risque est évalué en fonction de trois facteurs : l’âge de l’enfant, le caractère simple ou complexe de la crise, et l’examen clinique.Cette thèse avait pour objectif de tester l’hypothèse que parmi les enfants consultant pour une CEF, seuls ceux a
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32

Ramkissoon, Arthi. "Aids for the early diagnosis of tuberculous meningitis (TBM)." Thesis, 1985. http://hdl.handle.net/10413/2040.

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Mortality and morbidity rates associated with tuberculous meningitis (TBM) are substantial. The average duration of the untreated disease from onset to death is about 17 days. The prognosis of TBM is known to correlate with the stage of the disease at the time of diagnosis and commencement of chemotherapy. Early diagnosis improves the chances of recovery without neurological sequelae. Early diagnosis is a problem because the presenting symptoms are non-specific and the onset of the disease is typically insidious. To date no single test is available that is totally reliable and specific for TBM
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33

Jardim, Joana Carolina Vieira. "Infeções bacterianas invasivas em recém-nascidos nos últimos 10 anos." Master's thesis, 2018. http://hdl.handle.net/10316/82651.

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Trabalho Final do Mestrado Integrado em Medicina apresentado à Faculdade de Medicina<br>Introdução: O recém-nascido é particularmente suscetível a infeções, apresentando as de etiologia bacteriana um risco importante. Destas, as invasivas, que incluem a bacteriémia e meningite, são potencialmente muito graves, sendo habitual uma abordagem diagnóstica com investigação extensa. Este estudo pretende caracterizar os casos de infeção bacteriana invasiva em período neonatal, e avaliar se a aplicação dos scores de baixo risco de infeção bacteriana os identificariam como alvo de intervenção de baixo r
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34

Schutte, Clara-Maria. "Meningitis in South African adults : an evaluation of prognostic indicators, impact of HIV-infection, and diagnostic dilemmas." Thesis, 2002. http://hdl.handle.net/2263/29079.

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Meningitis remains a frightening disease with a high morbidity and mortality in spite of optimal treatment. In South Africa in particular, the incidence of HIV-infected patents with meningitis has risen considerably during the past decade. The first part of this meningitis study evaluated prognostic indicators in meningitis. In 100 adult patients with meningitis it was found that the Glasgow Coma Scale (GCS) at admission was a good indicator of the ultimate prognosis of the patient, with a GCS value of > 12 associated with a good outcome in 88% of patients. A GCS value of < 8 predicted an unfo
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Prömmel, Peter. "Meningeosis neoplastica: Der Einfluss von Tumorart und Liquorzellzahl auf die Diagnostik." Doctoral thesis, 2016. http://hdl.handle.net/11858/00-1735-0000-0028-87D7-1.

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Goerdt, Christoph. "Tau- und S-100b-Protein in der Differenzialdiagnose der bakteriellen Meningitis." Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F007-C.

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