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Dissertations / Theses on the topic 'Diagnostics of profit generation'

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1

Kotol, David. "Sample normalization using SIL standards fornext generation plasma diagnostics." Thesis, KTH, Skolan för bioteknologi (BIO), 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-214631.

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2

Jones-Evans, Angela. "The marketing of public library services for a profit." Thesis, University of Sheffield, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321853.

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3

Maksemous, Neven. "Development of high through-put neurogenetics diagnostics." Thesis, Queensland University of Technology, 2016. https://eprints.qut.edu.au/101097/1/Neven_Maksemous_Thesis.pdf.

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This project was an effort to improve the speed and affordability of genetic testing for neurological disorders. The research involved the development of a genetic diagnostic testing technique using Next Generation Sequencing technologies to investigate Familial Hemiplegic Migraine and related neurological conditions. The method successfully expanded the scope of testing, resulting in the ability to detect genetic changes that would have gone unnoticed in previous tests and significantly reduced the cost of testing for patients and the healthcare system.
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4

Meunier, Nadège. "Diagnostics observationnels du champ magnetique solaire : distribution spatiale, dynamique et processus de generation." Paris 7, 1997. http://www.theses.fr/1997PA077055.

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Ce travail presente plusieurs approches observationnelles complementaires de l'activite magnetique solaire. La nature de l'activite solaire n'est pas une question encore completement resolue, de meme que la question de son influence sur la terre. La dynamique associee aux structures actives, ainsi que la distribution spatiale et le role des differentes composantes sont abordes. L'accent est mis sur les variations des conditions physiques au cours du cycle. Je me suis tout d'abord interessee a la dynamique des facules photospheriques et chromospheriques. L'etude parallele des grandes et petites
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5

Austin, Dane R. "High-resolution interferometric diagnostics for ultrashort pulses." Thesis, University of Oxford, 2010. http://ora.ox.ac.uk/objects/uuid:03ff32ea-c82a-4a42-9c6b-11e42ddb1e67.

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I present several new methods for the characterisation of ultrashort pulses using interferometry. A generalisation of the concatenation algorithm for spectral shearing interferometry enables interferograms taken at multiple shears to be combined. This improves the precision of the reconstructed phase in the presence of detector noise, and enables the relative phase between disjoint spectral components to be obtained without decreasing the spectral resolution. The algorithm is applied to experimental data from two different implementations of spectral shearing interferometry for ultrashort opti
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6

Рудько, А. В. "Прибуток підприємства та шляхи його максимізації (на прикладі ПрАТ «Одеса-Авто»)". Thesis, Одеський національний економічний університет, 2021. http://local.lib/diploma/Rudko.pdf.

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Доступ до роботи тільки на території бібліотеки ОНЕУ, для переходу натисніть на посилання нижче<br>У роботі розглядаються теоретичні аспекти формування та підвищення прибутку. Проаналізовано загальні показники фінансового та техніко-економічного стану підприємства ПрАТ «Одеса-Авто», проведено аналіз показників прибутку та виявлення факторів впливу на підвищення прибутку підприємства ПрАТ «Одеса-Авто». Запропоновано заходи, метою яких виступає збільшення прибутку на підприємстві.<br>The work deals with the theoretical aspects formation and increase of profits Author analysis general indicato
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Ouyang, Wei Ph D. Massachusetts Institute of Technology. "Hierarchical selective electrokinetic concentration : the universal next-generation biomolecule enrichment technique for molecular diagnostics." Thesis, Massachusetts Institute of Technology, 2020. https://hdl.handle.net/1721.1/128323.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2020<br>Cataloged from PDF of thesis.<br>Includes bibliographical references (pages 182-200).<br>Rapid and reliable detection of ultralow-abundance nucleic acids and proteins in complex biological media may greatly advance clinical diagnostics and biotechnology development. Because of the slow mass transport and weak binding kinetics at ultralow concentration of target biomolecules, enrichment of target biomolecules plays an essential role in the detection of ultralow-abundance bio
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8

Moroz, Yuliya Yuzyfivna, and Maryna Viktorivna Plysak. "Conceptual aspects of the profit generation in the accounting system for management purposes." Thesis, National Aviation University, 2021. https://er.nau.edu.ua/handle/NAU/53921.

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1. Дорош Н. І., Кізенко Є. С. Особливості бухгалтерського обліку та оподаткування прибутку підприємств. Проблеми системного підходу в економіці : зб. наук. пр. Київ. Вип. 2 (76). 2020. C. 117-125. 2. Коцеруба Н.В., Гилюк Л.О. Фінансовий контроль формування, розподілу та використання прибутку суб’єкта господарювання. Причорноморські економічні студії. 2020. Т. 50. № 2. С. 155-161. 3. Національне положення (стандарт) бухгалтерського обліку 1 «Загальні вимоги до фінансової звітності»: Наказ Мінфіну України від 07.02.2013 р. № 73. URL: https://zakon.rada.go
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9

Zhu, Xiangyu. "Characterization of wood pellets combustion for clean energy generation." Electronic Thesis or Diss., Université de Lille (2022-....), 2023. http://www.theses.fr/2023ULILR016.

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Les thèmes de ma recherche sont de quantifier et comparer les caractéristiques de combustion et les émissions polluantes associées des pellets de bois naturel et des pellets noirs torréfiés.En contrôlant tous les paramètres de combustion (air entrant primaire et secondaire, débit de pellets, puissance de la chaudière), les principaux objectifs sont de :- Quantifier et comparer les caractéristiques de combustion des pellets de bois naturels et des pellets torréfiés sur un banc d'essai de combustion bien contrôlé.- De mesurer les émissions de polluants à l'aide d'analyseurs physicochimiques et p
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10

Moreno, Cabrera José Marcos. "A translational bioinformatics approach to improve genetic diagnostics of hereditary cancer using next-generation sequencing data." Doctoral thesis, Universitat de Barcelona, 2021. http://hdl.handle.net/10803/672364.

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This PhD thesis has been carried out with the aim of improving, from a bioinformatic-based approach, the genetic diagnostics of hereditary cancer. More specifically, the aims were: 1. To perform a comprehensive evaluation of tools suitable for detecting CNVs from NGS panel data at single-exon resolution. 2. To select the best candidate tool to implement in the genetic diagnostics pipeline of the ICO-IGTP program on hereditary cancer. 3. After implementing it, to evaluate the impact of including the selected NGS CNV detection tool as a first-tier screening step prior to MLPA validation. 4.
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Minardi, Raffaella <1987&gt. "Dominant and Recessive Polycystic Kidney Disease: A Novel Molecular Diagnostics Approach Based on Next-Generation Sequencing." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amsdottorato.unibo.it/7871/1/Minardi_Raffaella_Tesi.pdf.

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Polycystic Kidney Disease (PKD) is the most common genetic cause of kidney failure in children and adults and can be inherited as an autosomal dominant trait (ADPKD) or an autosomal recessive trait (ARPKD). ADPKD is the most common form, characterized by a late onset, caused by mutation in two causative gene PKD1 and PKD2; while ARPKD represents the rarest and most severe form, with early onset, caused by mutation in PKHD1 gene. The large size, the molecular complexity, the lack of mutational hotspot characterizing the causative genes and, in particular, the high homology of PKD1 with six pseu
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12

Kruber, Sebastian Alexey Joachim [Verfasser], and Dwayne R. J. [Akademischer Betreuer] Miller. "Next generation PIRL for surgery and bio-diagnostics / Sebastian Alexey Joachim Kruber ; Betreuer: Dwayne R. J. Miller." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2018. http://d-nb.info/1164158686/34.

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13

SANA, Maria Elena. "USE OF NEXT-GENERATION SEQUENCING FOR GENOMIC ANALYSIS IN COMPLEX DISEASES." Doctoral thesis, Università degli studi di Ferrara, 2013. http://hdl.handle.net/11392/2388840.

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Since the early 1990s, Sanger method has been the gold standard methodology for sequencing analysis of DNA. Next-generation sequencing (NGS) approaches revolutionized the field of genomics over the last 5 years. These new sequencing technologies make feasible the direct and cost-effective sequencing of genomes at unprecedented scale and speed. Furthermore, the applications of these technologies are wide-spread and have been developed to explore the complex biological systems, among which RNA sequencing (RNA-seq) for transcriptomics and ChIP-seq for epigenomics. NGS has changed the way we think
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14

Losik, Len. "Relying on Telemetry for Mission Critical Decisions: Lessons Learned from NASA's Reusable Launch Vehicle for Use on the Air Force's Next Generation Reusable Launch Vehicle." International Foundation for Telemetering, 2012. http://hdl.handle.net/10150/581746.

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ITC/USA 2012 Conference Proceedings / The Forty-Eighth Annual International Telemetering Conference and Technical Exhibition / October 22-25, 2012 / Town and Country Resort & Convention Center, San Diego, California<br>The U.S. Air Force's next generation reusable booster (NGRSB) offers the opportunity for the Space Command to use intelligent equipment for decision making replacing personnel, increasing safety and mission assurance by removing decisions from program management personnel who may not have had any flight-test experience. Adding intelligence to launch vehicle and spacecraft equipm
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15

Boriachek, Kseniia. "Next generation of human cancer diagnostics: Nanomaterial-based electrochemical sensors for clinically relevant exosomes and exosomal biomarkers analysis." Thesis, Griffith University, 2018. http://hdl.handle.net/10072/380570.

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Exosomes are 40-100 nm diameter membrane vesicles which are released from cells and circulate in body fluids such as blood, urine, and saliva. Being encapsulated by a lipid bilayer, these nanoscale vesicles carry a cargo of proteins, lipids, mRNA, microRNA (miRNA) and transfer this cargo to recipient cells. Exosomes play an important role in various biological processes such as intercellular signalling, coagulation, inflammation, cellular homeostasis and involved in many pathological conditions such as cancer progression and metastasis. Due to these unique properties, exosomes are being pursue
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16

Barbosa, dos Santos Freitas e. Sousa João. "Microplasma generation of high fluxes of singlet delta oxygen at atmospheric pressure for biomedical applications." Paris 11, 2010. http://www.theses.fr/2010PA112303.

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Dans ce travail, nous avons étudié expérimentalement la production à pression atmosphérique d'oxygène singulet delta, O2(a1Δg), par micro-plasmas. Nous avons développé un type particulier de microdécharges, appelées MCSD (micro-cathode sustained discharges) aptes à produire, en régime continu, des décharges luminescentes exemptes de transition en régime d'arc. Au moyen de diagnostics électrique et optique, le champ électrique réduit (E/N), la température du gaz (Tgaz), les profils de densité de l'oxygène atomique, la distribution spatiale de l'ozone, ainsi que la densité de O2(a1Δg) ont été ob
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17

Schranz, Katrin [Verfasser], and Heinrich [Akademischer Betreuer] Leonhardt. "Investigation of AML-specific FLT3 mutations – from next generation diagnostics to combined targeted therapy / Katrin Schranz ; Betreuer: Heinrich Leonhardt." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2019. http://d-nb.info/1184202648/34.

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18

Mahmoud, Nada. "Next-generation diagnostics of escherichia coli from community-onset sepsis patients in sweden : Studying the biodiversity of escherichia coli genomes." Thesis, Högskolan i Skövde, Institutionen för biovetenskap, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-19893.

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Escherichia coli (E. coli) is among the gram-negative bacteria that can cause several infections including sepsis. Confirmed sepsis patients must show a sequential organ failure assessment (SOFA) score of ≥2 with verified infection. Understanding the genotypic characteristics of E. coliclinical isolates from sepsis patients can help directing treatment strategies, tracking antibiotic resistance, and monitoring acquired virulence factors that can contribute to the severity of sepsis. The isolates included in this thesis were collected from confirmed sepsis patients (SOFA 2-3)during a prospectiv
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19

Courbet, Alexis. "Engineering autonomous and programmable biosensors through synthetic biology : integrating multiplexed biomarker detection and biomolecular signal processing into next-generation diagnostics." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONT3513.

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Les promesses de la médecine de précision dépendent de nouvelles solutions technologiques pour le diagnostic. Dans l’aire post-génomique, les approches de biologie synthétique pour la médecine apportent de nouvelles façon de sonder, monitorer et interfacer la physiopathologie humaine. Émergeant en tant que champ scientifique mature dont la transition clinique s’accélère, la biologie synthétique peut être utilisée pour appliquer des principes d’ingénierie afin de concevoir et construire des systèmes biologiques comprenant des spécifications cliniques. Une application particulièrement intéressan
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20

Alsayed, Ali Mohammed Ali. "Laser surface interaction for the generation of heavy cations and nanoparticles and their gas-phase studies." Rennes 1, 2008. http://www.theses.fr/2008REN1S027.

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In this thesis, we studied the recombination of the Azulene (C₁₀H₈⁺), Acenaphthene (C₁₂H₁₀⁺), Anthracene (C₁₄H₁₀⁺), and Pyrene (C₁₆H₁₀⁺) ions with electrons, with the FlaPI (Flowing Afterglow with Photo Ions) method. The ionic species in the flowing afterglow are spatially characterized by a quadrupole mass spectrometer and the electron concentration is measured by means of a movable Langmuir probe. We developed a new method L2DI (laser desorption / laser ionization) based on the FlaPI method for studying the recombination kinetics of much larger PAHs. We measured the PAH ions concentration de
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Robertson, Duncan A. "The strategy hypercube : a dynamic model for inter-firm competition and the generation of profit landscapes in turbulent environments." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.416766.

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22

Rush, Adam C. "An exploration of the influence of advertising exposure on the propensity to donate to non-profit organizations." Honors in the Major Thesis, University of Central Florida, 2009. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/1319.

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This item is only available in print in the UCF Libraries. If this is your Honors Thesis, you can help us make it available online for use by researchers around the world by following the instructions on the distribution consent form at http://library.ucf.edu/Systems/DigitalInitiatives/DigitalCollections/InternetDistributionConsentAgreementForm.pdf You may also contact the project coordinator, Kerri Bottorff, at kerri.bottorff@ucf.edu for more information.<br>Bachelors<br>Business Administration<br>Marketing
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23

Russo, Lorenzo. "Designing advanced nanomaterials for next generation in vitro diagnostics: development of optical and electrochemical biosensors for determination of viral and bacterial infections based on hollow AuAg nanoparticles." Doctoral thesis, Universitat Autònoma de Barcelona, 2019. http://hdl.handle.net/10803/666751.

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En esta tesis doctoral. El dibujo racional de nanomateriales avanzados con propiedades controladas se aplicó para su empleo en biosensing, y condujo al desarrollo de dos plataformas diagnosticas para la determinación de infecciones virales y bacterianas. Primero, se desarrolló un método sintético altamente reproducible y robusto para la producción de nanoshells de una aleación AuAg monodispersas basado en remplazamiento galvánico. El protocolo descrito permite el controlo preciso sobre la morfología de las partículas, en términos de grosor de la capa externa y de tamaño del vacío interior, la
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Жмайлова, О. Г. "Теоретико-методичні підходи до аналізу абсолютних показників прибутку комерційного банку". Thesis, Українська академія банківської справи Національного банку України, 2013. http://essuir.sumdu.edu.ua/handle/123456789/59574.

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Висвітлено теоретико-методичні підходи до аналізу абсолютних показників прибутку комерційного банку. Вивчено фактори, що впливають на прибуток: власний капітал, ефективність управління податками, ефективність контролю витрат, ефективність управління активами, ефективність управління ресурсами; зв'язок між ними, який виражається мультиплікативною моделлю.<br>Deals with theoretical and methodological approaches to the analysis of absolute rates of profit commercial bank. Studied the factors affecting the profit: equity, efficiency of tax administration, the effectiveness of cost control, asset
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Trujillano, Lidón Daniel 1987. "Mendelian disease gene identification and diagnosis using targeted next generation sequencing." Doctoral thesis, Universitat Pompeu Fabra, 2013. http://hdl.handle.net/10803/295582.

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Les tecnologies de seqüenciació de nova generació (NGS) han emergit com a una poderosa eina per al descobriment de mutacions causals i nous gens per a malalties Mendelianes, i estan tenint un ràpid impacte en l’àmbit del diagnòstic genètic. Les tecnologies de NGS es poden utilitzar en combinació amb mètodes d’enriquiment de l’ADN per a seqüenciar en profunditat regions genòmiques diana, com l’exoma o gens associats a malalties, entregant informació genètica d’una manera ràpida, barata i acurada. Aquesta tesi descriu l’aplicació de la NGS dirigida per a identificar un nou gen per a la hipertens
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STEINFELDER, ROBERT SEBASTIAN. "Development and implementation of novel applications of massively parallel sequencing in precision medicine." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2016. http://hdl.handle.net/10281/114589.

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Next-generation sequencing (NGS) based on “sequencing by synthesis”, such as Illumina’s MiSeq, NextSeq500 or HiSeq instruments has reached a state where consistency, throughput and quality make it a mature technology to use for cancer genome research, such as single-cell sequencing or in clinical diagnostics. Within the scope of this thesis, we designed and tested three protocols to mobilise high-throughput sequencing for precision medicine to provide optimal solutions for doctors to help with understanding, diagnosing and determining states of human cancer cells. Targeted re-sequencing of cli
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27

Lännevall, Joel. "Operation dependent costs of non-optimal hydropower production : Effects on the operational pattern of the Small Lule River." Thesis, Uppsala universitet, Elektricitetslära, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-294867.

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In the present electrical market there is an increasing penetration of intermittent energy sources. Several studies have examined its effect on the planning of hydropower operation and the conclusion is that an increasing intermittent production is likely to result in a more variable hydropower operation, utilising a wider span of operational set points. The wear of a hydropower unit is generally at a minimum when operated close to best efficiency and increases when operating at higher or lower set points. This study introduces a method to calculate an operation dependent cost (ODC) function f
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Остапенко, Олена Анатоліївна, та Olena Anatoliivna Ostapenko. "Діагностика фінансово-економічної діяльності підприємства та можливості поліпшення її результатів". Master's thesis, СумДПУ імені А. С. Макаренка, 2021. http://repository.sspu.edu.ua/handle/123456789/12069.

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Об’єкт дослідження – фінансово-економічна діяльність ТОВ «Медтехніка-Суми». Предметом дослідження є принципи, методи та практичні аспекти діагностики фінансово-економічної діяльності підприємства та підвищення її ефективності. Мета магістерської роботи – діагностика фінансово-економічної діяльності підприємства та розробка й обґрунтування пропозицій щодо підвищення її результативності. У магістерській роботі розглянуто теоретичні та методичні засади діагностики фінансово-економічної діяльності підприємства, досліджено можливості підвищення результативності фінансово-економічної діяльності
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Forestier-Colleoni, Pierre. "Etude expérimentale des champs magnétiques en surface d'une cible irradiée par laser et leurs implications sur le faisceau d'électrons." Thesis, Bordeaux, 2016. http://www.theses.fr/2016BORD0036/document.

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Cette thèse porte sur la caractérisation des champs magnétiques générés par l'interaction entre un laser d'intensité de 1017 W/cm2 à 1018 W/cm2 et de cibles solides, et leurs effets sur le faisceau d'électrons chauds. En effet, les différents champs magnétiques créés lors de cette interaction ont un rôle fondamental sur les caractéristiques du faisceau d'électrons chauds : sa source et son transport dans la matière. Des diagnostics de polarimétrie et d'interférométrie croisée ont été développés lors de cette thèse pour observer le champ magnétique en surface de la cible irradiée par laser et e
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Sánchez, Monteagudo Ana. "Genética molecular y biomarcadores de la enfermedad de Wilson." Doctoral thesis, Universitat Politècnica de València, 2023. http://hdl.handle.net/10251/171454.

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[ES] La enfermedad de Wilson (EW) es un trastorno hereditario del metabolismo del cobre causado por mutaciones en ATP7B, que codifica una proteína transportadora de cobre en el hígado. Su mal funcionamiento provoca un fallo en la excreción biliar de cobre y una acumulación progresiva de este metal en el organismo, especialmente en hígado y cerebro. En este trabajo, se explora la posible utilidad de miRNAs circulantes en plasma para identificar biomarcadores que sirvan para controlar la progresión de la enfermedad en pacientes con EW bajo tratamiento. Los modelos desarrollados para cada miRNA m
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Огірко, О. І., та O. I. Ohirko. "Інформаційна технологія для визначення енергетичних характеристик поверхневих шарів металів: дисертація". Thesis, Українська академія друкарства, 2013. http://dspace.lvduvs.edu.ua/handle/1234567890/657.

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Огірко О. І. Інформаційна технологія для визначення енергетичних характеристик поверхневих шарів металів: дисертація на здобуття наукового ступеня кандидата технічних наук за спеціальністю 05.13.06 –інформаційні технології / Огірко Ольга Ігорівна. - Львів: Українська академія друкарства, 2013. - 163 с.<br>Дисертація присвячена розробці інформаційної технології для відбору та опрацювання даних, які характеризують поверхневі шари металів в агресивному середовищі. Розроблено концептуальну модель комп’ютерної інформаційної технології, що передбачає використання фізико-математичних моделей для обчи
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Novotný, Tomáš. "Využití obnovitelných zdrojů realizací fotovoltaické elektrárny Drásov." Master's thesis, Vysoké učení technické v Brně. Fakulta podnikatelská, 2009. http://www.nusl.cz/ntk/nusl-222290.

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This master’s thesis discuss the renewable energy source utilisation, to be more precise it describes the Photovoltaic Power Plants. These sources are not only capable of contributing to the regeneration of the environment and to the electricity production, but they are also capable of generating the investor’s economic profit. The individual chapters describe the external factors affecting the project, present condition of the project’s realization, the theory of photovoltaic cells and systems, CCTV camera systems, which are necessary for the power plant security.
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Lönnberg, Joakim. "Short-term regulating capacity and operational patterns of The Lule River with large wind power penetration." Thesis, Uppsala universitet, Elektricitetslära, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-230972.

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The growing share of installed wind power in the Swedish electricity system has caused concerns whether the available regulating power will be sufficient. Several studies have examined the need of regulating power using both statistical and modelling approaches. However, there is a risk that some aspects of the short-term regulation of hydropower might have been missed. By using one of Vattenfall’s hydropower planning tools, the short-term operation of The Lule River has been simulated with an increasing penetration of wind power. The tool includes detailed models of reservoirs, generating uni
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Плотнікова, А. В. "Економічне обґрунтування стратегії розвитку підприємства (на прикладі ТОВ «Юг-Поліграф»)". Thesis, 2018. http://dspace.oneu.edu.ua/jspui/handle/123456789/9538.

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У роботі розглядаються поняття та класифікація стратегії розвитку підприємства, етапи та методологічні аспекти її розробки. Проаналізовано організаційно-економічну та фінансово-господарську діяльність ТОВ «Юг-Поліграф», проведена оцінка зовнішнього середовища, обґрунтовано необхідність розробки стратегії розвитку підприємства. Запропоновано план заходів щодо формування стратегії розвитку на ТОВ «Юг-Поліграф», проведено оцінку економічної ефективності запропонованого проекту, виявлено можливі ризики проекту та шляхи їх мінімізації.<br>The concept and classification of enterprise development str
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Vigliar, Elena. "Integration of Next-generation sequencing technologies in pathological diagnostics." Tesi di dottorato, 2017. http://www.fedoa.unina.it/11491/1/Tesi%20Dottorato%20Elena%20Vigliar.pdf.

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Today, with the better understanding of the molecular events involved in malignancy and the mechanisms of pharmacotherapy, larger gene panels are more helpful than single biomarker detection. After the completion of the first human genome sequence in 2004, the growing need to sequence a large number of individual genomes in a fast, low-cost and accurate way has directed a shift from traditional Sanger sequencing methods towards new high-throughput genomic technologies. In 2005, the development of next generation sequencing (NGS) methods has represented one of the more significant technical adv
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Tsai, Ming-Rung, and 蔡明容. "Clinical Application of Higher Harmonic Generation Microscopy in Superficial Disease Diagnostics." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/80129009179592453382.

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博士<br>國立臺灣大學<br>光電工程學研究所<br>101<br>Cancer is a major health problem that has significant impacts worldwide. Approximately 12.7 million cancer cases and 7.6 million cancer deaths were reported among U.S. residents in 2008. Thus, early detection and treatment are critical to reduce the mortality of the disease. Cancer can be detected in a number of ways; however, the most definitive diagnoses are usually achieved through biopsy. Biopsy is often uncomfortable and exposes patients to a wide spectrum of potential risks and complications, such as tissue trauma, bleeding, and spread of cancer cells.
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Carroll, Brian Christopher. "Droplet generation and mixing in confined gaseous microflows." 2012. http://hdl.handle.net/2152/19508.

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Fast mixing remains a major challenge in droplet-based microfluidics. The low Reynolds number operating regime typical of most microfluidic devices signify laminar and orderly flows that are devoid of any inertial characteristics. To increase mixing rates in droplet-based devices, a novel technique is presented that uses a high Reynolds number gaseous phase for droplet generation and transport and promotes mixing through binary droplet collisions at velocities near 1m/s. Control of multiple gas and liquid streams is provided by a newly constructed microfluidic test bed that affords the stringe
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Chao-Kuei, Lee, and 李晁逵. "Optical Parametric Amplification: Applications in Generation of ultrafast Optical Pulses and Diagnostics of ultraweak signal." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/05864297205842848627.

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博士<br>國立交通大學<br>光電工程所<br>92<br>In this dissertation, using the noncollinear optical parametric amplification (NOPA), a novel tunable blue/UV femtosecond laser system, characterization of ultraweak signal, and ultrabroad band OPA were developed. This femtosecond laser source can remove the tuning gap of a typical femtosecond-laser-based optical parametric amplifier without additional frequency conversion devices. The new source can be highly useful fro studies of topics ranging from wide-bandgap material to biophotonics. For the characterization of ultraweak signal, the optical parametric ampli
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Pinto, Maria de Azevedo. "Application and verification of Next-Generation Sequencing (NGS) for the molecular diagnostics of brain tumours." Master's thesis, 2017. http://hdl.handle.net/10451/35999.

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Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2017<br>Primary brain tumours are a critical cause of morbidity and mortality in both adults and children, representing around 1-2% of all newly diagnosed tumours and accounting for about 2% of all cancer-related deaths. Gliomas are the most prevalent primary malignant brain tumour representing 80% of these. Over the past years, distinctive genetic profiles have been identified in several glioma types which have led to the WHO 2016 new classification of CNS tumours that incorporates mol
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Mehta, Krunal Atul Cavalier Tom M. "Design and implementation of column generation to solve large-scale profit-maximization forest management problems." 2008. http://www.etda.libraries.psu.edu/theses/approved/WorldWideIndex/ETD-2796/index.html.

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Sharma, Deepak. "Generation Capacity Expansion Planning in Deregulated Electricity Markets." Thesis, 2009. http://hdl.handle.net/10012/4449.

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With increasing demand of electric power in the context of deregulated electricity markets, a good strategic planning for the growth of the power system is critical for our tomorrow. There is a need to build new resources in the form of generation plants and transmission lines while considering the effects of these new resources on power system operations, market economics and the long-term dynamics of the economy. In deregulation, the exercise of generation planning has undergone a paradigm shift. The first stage of generation planning is now undertaken by the individual investors. These inve
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(7046468), Wesley Allen Davis. "Value Generation and Capture in the Agri-Food Value Chain." Thesis, 2019.

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<p>How do food and agribusiness firms capture more profit in their value chain? How do innovative managers identify attractive adjacency and disintermediation opportunities? What options are available to a manager facing these questions and what economic incentives might motivate their strategic behavior? This study sought to address these timely questions, more effectively understand the strategic decisions facing food and agribusiness managers relative to value chain profit pools, and uncover some of the hidden dynamics between chain participants. Specifically, this study defines and quantif
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Ni, Ming-Hai, and 倪明海. "Modeling the Optimal Launching Timing and Price-Setting of Second-Generation Product to Maximize Overall Profit." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/48296127171771423575.

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博士<br>中華大學<br>科技管理學系(所)<br>99<br>The rapid changes in technology, market competition, globalization, and the requirements for product differentiation are causing industries that employ product life cycle management (PLCM) to become more meticulous High-tech industries such as information technology, semiconductors, optoelectronics and aerospace are sensitive to product life cycle management, especially in relation to stage transition, timing control and price-setting. PLCM can significantly influence the corporate performance, profit acquisition and the achievement of business goals and can ul
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CHEN, WAN-RU, and 陳婉如. "An Analysis of Operational Efficiency of Non-Profit Proprietary Hospitals after the Second Generation NHI in Taiwan." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/7ykpgf.

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碩士<br>南華大學<br>財務金融學系財務管理碩士班<br>107<br>Since the launch of the National Health Insurance, the financial problems have been serious. Therefore, the second-generation health insurance was born in 2013, but the hospital operating environment is even more difficult. In this study, the data envelopment analysis method was used to evaluate the performance of the second-generation health care hospitals during the period of 2013-2017. It was found that the performance of the hospitals in 22 counties and cities in Taiwan after the implementation of the second-generation health insurance was obviously de
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TSAI, MEI-SHU, and 蔡美淑. "Chain Store Branding System towards Profit-Mining of Self New Branding and Second Generation of New Retailing Store." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/26mwen.

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碩士<br>逢甲大學<br>經營管理碩士在職學位學程<br>107<br>Abstract According to data compiled by the Taiwan Beverage Industries Association, the annual gross sales of the beverage market in Taiwan are about 54 billion dollars. Although the beverage market in Taiwan is becoming mature, it is still growing slowly annually. Companies have been introducing innovative beverages targeting different groups and spending habits. Chain restaurants have been advertising for franchisees at trade shows year round to attract those interested in starting their own business and to more quickly increase market recognition and mar
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Vorster, Johan Christi. "Alternative electricity generation : Safripol as a case study / Johan Christi Vorster." Thesis, 2014. http://hdl.handle.net/10394/15804.

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Electrical energy supply in South Africa, provided by ESKOM, has become more expensive with regular price increases in the past seven years. Increases on an annual basis have seen the Mega flex tariffs quadruple in the years from 2007 to 2014. ESKOM is the sole supplier of electricity to Safripol, a polymer producer of which the manufacturing facility is located in Sasolburg, South Africa. This study will provide contextual information on what impact the escalation in cost of this utility has on the financial returns of the business. Independent power generation within the boundaries of the ma
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Howe, John Andrew. "A New Generation of Mixture-Model Cluster Analysis with Information Complexity and the Genetic EM Algorithm." 2009. http://trace.tennessee.edu/utk_graddiss/863.

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In this dissertation, we extend several relatively new developments in statistical model selection and data mining in order to improve one of the workhorse statistical tools - mixture modeling (Pearson, 1894). The traditional mixture model assumes data comes from several populations of Gaussian distributions. Thus, what remains is to determine how many distributions, their population parameters, and the mixing proportions. However, real data often do not fit the restrictions of normality very well. It is likely that data from a single population exhibiting either asymmetrical or nonnormal tail
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Мирон, Ю. В. "Стратегія росту прибутку підприємства". Thesis, 2017. http://dspace.oneu.edu.ua/jspui/handle/123456789/7889.

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Кваліфікаційна робота магістра складається з трьох розділів. Об’єкт дослідження – прибуток підприємства. У роботі розглядаються теоретичні аспекти прибутку підприємства та його формування, стратегії управління прибутком підприємства. Проаналізовано отриманий чистий прибуток підприємства за 2012-2016 рр. та техніко-економічний стан підприємства загалом. Запропоновано заходи, які посприяють росту прибутку підприємства у наступному періоді.<br>Thesis consists of three chapters. Object of study profit of the enterprise. Diploma thesis deals with theoretical aspects of enterprise profit
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Лукава, І. В. "Управління прибутком підприємства". Thesis, 2018. http://dspace.oneu.edu.ua/jspui/handle/123456789/7612.

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У роботі розглядаються теоретико-методологічні основи управління прибутком підприємства. Здійснена оцінка господарської діяльності ДП «Морський торгівельний порт Чорноморськ». Проведений аналіз показників прибутковості та рентабельності підприємства, формування, розподілу і використанням прибутку на підприємстві. Запропоновані рекомендації щодо формування стратегії управління прибутком на підприємстві. Розроблені та економічно обґрунтовані заходи щодо підвищення прибутковості підприємства.<br>В работе рассматриваются теоретико-методологические основы управления прибылью предприятия. Осуществле
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Matějčková, Iva. "Využití sekvenačních metod nové generace pro objasnění fenotypu podobného CF u pacientů s nejasnou molekulární podstatou onemocnění." Master's thesis, 2017. http://www.nusl.cz/ntk/nusl-355983.

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Cystic fibrosis (CF) is genetically conditioned, autosomal recessive disease that occurs in the European population with a prevalence of about 1:2500 - 1:1800. In this disease we observe a mutation of the CTFR gene with subsequent fault in chloride channels. Such afflicted individuals usually suffer from chronic respiratory problems, pancreatic insufficiency, high concentration of chloride ions in sweat and obstructive azoospermia. Genetic testing of CFTR gene is indicated in individuals who meet the CF clinical picture and a positive sweat test (increased concentration of chlorides in the swe
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