Relevant bibliographies by topics / Diazonamid

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Diazonamid'

Author: Grafiati
Published: 4 June 2021
Last updated: 12 February 2022

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Journal articles on the topic "Diazonamid"

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Roos, Martin. "Diazonamid attackiert Mikrotubuli." Im Focus Onkologie 20, no. 1-2 (2017): 10. http://dx.doi.org/10.1007/s15015-017-3076-6.

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Li, Jing, Susan Jeong, Lothar Esser, and Patrick G. Harran. "Total Synthesis of Nominal Diazonamides-Part 1: Convergent Preparation of the Structure Proposed for (−)-Diazonamide A." Angewandte Chemie International Edition 40, no. 24 (2001): 4765–69. http://dx.doi.org/10.1002/1521-3773(20011217)40:24<4765::aid-anie4765>3.0.co;2-1.

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Li, Jing, Susan Jeong, Lothar Esser, and Patrick G. Harran. "Total Synthesis of Nominal Diazonamides—Part 1: Convergent Preparation of the Structure Proposed for (−)-Diazonamide A." Angewandte Chemie 113, no. 24 (2001): 4901–6. http://dx.doi.org/10.1002/1521-3757(20011217)113:24<4901::aid-ange4901>3.0.co;2-0.

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Li, Jing, Susan Jeong, Lothar Esser, and Patrick G. Harran. "ChemInform Abstract: Total Synthesis of Nominal Diazonamides. Part 1. Convergent Preparation of the Structure Proposed for (-)-Diazonamide A." ChemInform 33, no. 21 (2010): no. http://dx.doi.org/10.1002/chin.200221205.

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Nicolaou, K. C., and Jason S. Chen. "Total synthesis of complex heterocyclic natural products." Pure and Applied Chemistry 80, no. 4 (2008): 727–42. http://dx.doi.org/10.1351/pac200880040727.

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Total synthesis campaigns toward complex heterocyclic natural products are a prime source of inspiration for the design and execution of complex cascade sequences, powerful reactions, and efficient synthetic strategies. We highlight selected examples of such innovations in the course of our total syntheses of diazonamide A, azaspiracid-1, thiostrepton, 2,2'-epi-cytoskyrin A and rugulosin, abyssomycin C, platensimycin, and uncialamycin.
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Yuen, Alexander K. L., and Craig A. Hutton. "Preparation of Cyclic Peptide Alkaloids Containing Functionalized Tryptophan Residues." Natural Product Communications 1, no. 10 (2006): 1934578X0600101. http://dx.doi.org/10.1177/1934578x0600101010.

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This review covers the synthesis of various cyclic peptide natural products possessing highly functionalized tryptophan residues, focusing on the examples of diazonamide A, the TMC-95 compounds, the celogentin/moroidin family and the complestatin/chloropeptin system. Recent efforts toward the preparation of these modified-tryptophan-containing peptides will be outlined, focusing primarily on the novel methods for the assembly of the highly functionalized indole/tryptophan moieties at the core of these structures.
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Knowles, Robert R., Joseph Carpenter, Simon B. Blakey, et al. "Total synthesis of diazonamide A." Chem. Sci. 2, no. 2 (2011): 308–11. http://dx.doi.org/10.1039/c0sc00577k.

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Nicolaou, K. C., Marco Bella, David Y. K. Chen, Xianhai Huang, Taotao Ling, and Scott A. Snyder. "Total Synthesis of Diazonamide A." Angewandte Chemie International Edition 41, no. 18 (2002): 3495–99. http://dx.doi.org/10.1002/1521-3773(20020916)41:18<3495::aid-anie3495>3.0.co;2-7.

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Li, Jing, Xin Chen, Anthony W. G. Burgett, and Patrick G. Harran. "Synthetic seco Forms of (−)-Diazonamide A." Angewandte Chemie International Edition 40, no. 14 (2001): 2682–85. http://dx.doi.org/10.1002/1521-3773(20010716)40:14<2682::aid-anie2682>3.0.co;2-r.

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Li, Jing, Xin Chen, Anthony W. G. Burgett, and Patrick G. Harran. "Synthetic seco Forms of (−)-Diazonamide A." Angewandte Chemie 113, no. 14 (2001): 2754–57. http://dx.doi.org/10.1002/1521-3757(20010716)113:14<2754::aid-ange2754>3.0.co;2-h.

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Dissertations / Theses on the topic "Diazonamid"

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Radspieler, Alexander. "Untersuchungen zur Synthese von Diazonamid A und Phorbazol A und C." Doctoral thesis, [S.l. : s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=960868712.

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Radspieler, Alexander [Verfasser], H. G. [Gutachter] Schmalz, Jürgen [Gutachter] Liebscher, and U. [Gutachter] Koert. "Untersuchungen zur Synthese von Diazonamid A und Phorbazol A und C / Alexander Radspieler ; Gutachter: H.-G. Schmalz, Jürgen Liebscher, U. Koert." Berlin : Humboldt-Universität zu Berlin, 2000. http://d-nb.info/120766801X/34.

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Kreisberg, Jennifer Diane. "Studies directed towards the total synthesis of the natural product diazonamide A." Access restricted to users with UT Austin EID Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3037513.

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Hind, Sarah Lucy. "Synthetic approaches to diazonamide A." Thesis, University of Exeter, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.245947.

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David, Nadege. "Towards the synthesis of diazonamide A." Thesis, University of Nottingham, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.582017.

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This thesis describes a new approach towards a formal synthesis of the marine natural product diazonamide A. Firstly, the biological anti-cancer activity of diazonamide A is explained. The investigations towards the synthesis of the C-10 quaternary centre by numerous laboratories are then reported, as well as the successful total and formal syntheses. Secondly, our strategy is presented. One of the difficulties of the synthesis is the generation of the quaternary centre at C-10. This project aims to construct this stereocentre based on a novel strategy, involving the synthesis of a 3,3- disubs
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Sammons, Matthew F. "Studies directed toward the synthesis of diazonamide A." Connect to online resource, 2008. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3337224.

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Meyer, Falco-Magnus. "Studies towards the total synthesis of diazonamide A." Thesis, University of Cambridge, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608416.

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Churchill, Gwydion H. "Synthetic studies towards the marine natural product diazonamide A." Thesis, University of Nottingham, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.423661.

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Green, Clive P. "Synthetic studies towards the cytotoxic marine natural product diazonamide A." Thesis, University of Nottingham, 1999. http://eprints.nottingham.ac.uk/13863/.

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The thesis describes synthetic studies towards the marine natural product diazonamide A. This unprecedented compound was recently isolated from a colonial ascidian and displays exceptional levels of cytotoxic activity against human cancer cell lines. The Introduction includes an account of how diazonamide A was isolated and its structure determined. This is followed by a summary of the different natural products which have been isolated from ascidians, and highlights the structural similarities between these compounds and diazonamide A. The Introduction concludes with a review of structurally
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Denizot, Natacha. "Couplages oxydants entre indoles et phénols pour la synthèse de benzofuroindolines naturelles." Thesis, Université Paris-Saclay (ComUE), 2015. http://www.theses.fr/2015SACLS147/document.

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Le noyau benzofuro[2,3-b]indoline est une structure complexe que l’on retrouve dans différentes substances naturelles telles que l’azonazine, la voacalgine A, la bipleiophylline ou encore le diazonamide A. Ces produits naturels possèdent une activité biologique intéressante et plus particulièrement le diazonamide A avec un IC50 inférieur à 15ng/mL sur plusieurs lignées cellulaires cancéreuses. De plus, certaines de ces substances n’ont jamais été synthétisées à ce jour. Lors de la biogénèse de ces composés, il est supposé que le motif benzofuroindoline est créé par un couplage oxydant entre un
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Book chapters on the topic "Diazonamid"

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Taber, Douglass F. "Alkaloid Synthesis: (−)-α-Kainic Acid (Ohshima), Serpentine (Scheidt), (−)-Galanthamine ( Jia), (+)-Trigolutes B (Gong), Sarain A (Yokoshima/Fukuyama), DZ-2384 (Harran)." In Organic Synthesis. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190646165.003.0060.

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(−)-α-Kainic acid 3 is widely used in neuropharmacological studies. En route to 3, Takashi Ohshima of Kyushu University found (Chem. Eur. J. 2015, 21, 3937) that the intramolecular ene cyclization of 1 delivered 2 with high diastereocontrol. Karl A. Scheidt of Northwestern University set (Angew. Chem. Int. Ed. 2015, 54, 6900) the absolute configuration of 5 and so of serpentine 6 by the organocatalyzed cyclization of 4. This is the first total synthesis of that alkaloid. Yanxing Jia of Peking University prepared (Angew. Chem. Int. Ed. 2015, 54, 6255) the benzofuran 8 by the Pd-mediated cyclization of the alkyne 7. An organo­catalyzed intermolecular Michael addition set the absolute configuration of (−)-galanthamine 9. Liu-Zhu Gong of the University of Science and Technology of China assem­bled (Chem. Eur. J. 2015, 21, 8389) (+)-trigolutes B 13 by the organocatalyzed addition of 10 to 11 to give 12. Barry M. Trost of Stanford University employed (Chem. Sci. 2015, 6, 349) a similar strategy in a synthesis of (−)-perophoramidine (not illustrated). Satoshi Yokoshima and Tohru Fukuyama of Nagoya University showed (Angew. Chem. Int. Ed. 2015, 54, 7367) that on deprotection, 14 was converted to an eight-membered cyclic nitrone, that further cyclized to 15. This set the stage for the synthesis of sarain A 16. Patrick G. Harran of UCLA has extensively studied the complex alkaloid (−)-diazonamide A (not illustrated). Structural simplification and optimization of antimitotic activity led to the macrolactam DZ-2384 18. It is exciting that 18 could be prepared (Angew. Chem. Int. Ed. 2015, 54, 4818) on a multigram scale by selective electrochemical oxidation of the much simpler precursor 17.
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Conference papers on the topic "Diazonamid"

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Li, Lin, Qi Wei, Ming Zhou, et al. "Abstract B50: A new class of diazonamide analogs with improved antitumor activity." In Abstracts: AACR International Conference on Translational Cancer Medicine-- Jul 11-14, 2010; San Francisco, CA. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1078-0432.tcmusa10-b50.

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Li, Lin, Wei Qi, Ming Zhou, et al. "Abstract 5423: New diazonamide analogs demonstrate remarkably larger therapeutic window compared to taxanes and vinca alkaloids in rodents." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-5423.

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Wieczorek, Michal, Joseph Tcherkezian, Cynthia Bernier, et al. "Abstract A188: Diazonamide DZ 2384, a potential therapeutic for pancreatic cancer, binds to tubulin with a unique impact on microtubule dynamics and tubulin curvature." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; November 5-9, 2015; Boston, MA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1535-7163.targ-15-a188.

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Journal articles Dissertations / Theses
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