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Relevant bibliographies by topics / Dicarboxylic Amino acids

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Academic literature on the topic 'Dicarboxylic Amino acids'

Author: Grafiati

Published: 4 June 2021

Last updated: 28 July 2025

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Journal articles on the topic "Dicarboxylic Amino acids"

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Allan, RD, RK Duke, TW Hambley, et al. "Synthesis of Unsaturated Analogues of Glutamic Acid: Amination of Trianions From Unsaturated Dicarboxylic Acids With Chloramine." Australian Journal of Chemistry 49, no. 7 (1996): 785. http://dx.doi.org/10.1071/ch9960785.

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Trianions can be formed from dicarboxylic acids which contain a β,γ -double bond, and amination with chloramine yields β,γ-unsaturated α-amino acids. This methodology provides a convenient synthesis of amino acids that are inaccessible by other routes. (Z)-3-Phenylthiopent-2-enedioic acid and all four stable unsaturated analogues of the conformationally restricted glutamate analogue 1-aminocyclopentane-1,3-dicarboxylic acid have been synthesized to demonstrate the applicability of the method. The structure of one of the amino acid products, (�)-cis-1-aminocyclopent-4-ene-1,3-dicarboxylic acid

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Eronen, Aleksi E. K., Jere K. Mannisto, Karina Moslova, Martin Nieger, Eeva Heliövaara, and Timo Repo. "Synthesis of Diaryl Hydroxyl Dicarboxylic Acids from Amino Acids." Journal of Organic Chemistry 85, no. 9 (2020): 5799–806. http://dx.doi.org/10.1021/acs.joc.9b03320.

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Meldrum, Brian. "Possible Therapeutic Applications of Antagonists of Excitatory Amino acid Neurotransmitters." Clinical Science 68, no. 2 (1985): 113–22. http://dx.doi.org/10.1042/cs0680113.

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The dicarboxylic amino acids, glutamate and aspartate, are excitatory neurotransmitters in many brain regions. Recent animal experiments with analogues of dicarboxylic amino acids that block their excitatory actions, suggest that such selective antagonists could have important therapeutic uses in neurology and psychiatry. The strongest evidence concerns epilepsy and disorders of the motor system. However, there are theoretical and experimental grounds for studying therapeutic applications in cerebral ischaemia and in chronic degenerative disorders. This review summarizes the experimental backg

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Bröer, Stefan. "Apical Transporters for Neutral Amino Acids: Physiology and Pathophysiology." Physiology 23, no. 2 (2008): 95–103. http://dx.doi.org/10.1152/physiol.00045.2007.

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Absorption of amino acids in kidney and intestine involves a variety of transporters for different groups of amino acids. This is illustrated by inherited disorders of amino acid absorption, such as Hartnup disorder, cystinuria, iminoglycinuria, dicarboxylic aminoaciduria, and lysinuric protein intolerance, affecting separate groups of amino acids. Recent advances in the molecular identification of apical neutral amino acid transporters has shed a light on the molecular basis of Hartnup disorder and iminoglycinuria.

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Shoukry, Mohamed M., and Sameya M. T. Ezzat. "Palladium(II) Complexes Containing Mixed Nitrogen-Sulphur Donor Ligands: Interaction of [Pd(Methionine Methyl Ester)(H2O)2]2+with Biorelevant Ligands." Bioinorganic Chemistry and Applications 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/382646.

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Pd(MME)Cl2complex (MME = methionine methyl ester) was synthesised and characterized by physicochemical measurements. The reaction of [Pd(MME)(H2O)2]2+with amino acids, peptides, or dicarboxylic acids was investigated at 25°C and 0.1 M ionic strength. Amino acids and dicarboxylic acids form 1 : 1 complexes. Peptides form both 1 : 1 complexes and the corresponding deprotonated amide species. The stability of the complexes formed was determined and the binding centres of the ligands were assigned. Effect of solvent on the stability constant of Pd(MME)-CBDCA complex, taken as a representative exam

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Chohan, Zahid H. "Symmetric 1,1'-Dimethylferrocene-Derived Amino Acids: Their Synthesis, Characterization, Ligational and Biological Properties With Cu(II), Co(II) and Ni(II) Ions." Metal-Based Drugs 7, no. 4 (2000): 177–83. http://dx.doi.org/10.1155/mbd.2000.177.

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Some novel symmetric 1,1′-dimethylferrocene derived amino acids have been prepared by the reaction of 1,1′-ferrocenedimethyldichloride with amino acids (glycine, alanine, phenylalanine and tyrosine). Their Cu(II), Co(II) and Ni(II) complexes, of the type [M(L)] where [M = Cu(II) and L = L1-L5] and [M(L)Cl2] where [M-Co(II)and Ni(II), L = L1-L5] have been prepared. The dicarboxylic acids and their metal complexes were characterized by their physical, analytical and spectral data. The [M(L)] complexes showed a square planar geometry whereas an octahedral geometry was observed for [M(L)Cl2] compl

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El-Sherif, Ahmed, Mohamed Shoukry, Ramadan El-Bahnasawy, and Dalia Ahmed. "Complex formation reactions of palladium(II)-1,3-diaminopropane with various biologically relevant ligands. Kinetics of hydrolysis of glycine methyl ester through complex formation." Open Chemistry 8, no. 4 (2010): 919–27. http://dx.doi.org/10.2478/s11532-010-0057-4.

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AbstractThe interaction of [Pd(DAP)(H2O)2]2+ (DAP = 1,3-diaminopropane) with some selected bio-relevant ligands, containing different functional groups, were investigated. The ligands used are dicarboxylic acids, amino acids, peptides and DNA constituents. Stoichiometry and stability constants of the complexes formed are reported at 25°C and 0.1 M ionic strength. The results show the formation of 1:1 complexes with amino acids and dicarboxylic acids. The effect of chelate ring size of the dicarboxylic acid complexes on their stability constants is examined. Peptides form both 1:1 complexes and

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Roy, Siddhartha, Desh Deepak Singh, and M. Vijayan. "X-ray studies on crystalline complexes involving amino acids and peptides. XLII. Adipic acid complexes of L- and DL-arginine and supramolecular association in arginine–dicarboxylic acid complexes." Acta Crystallographica Section B Structural Science 61, no. 1 (2005): 89–95. http://dx.doi.org/10.1107/s0108768104030010.

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The adipic acid complexes of DL-arginine and L-arginine are made up of zwitterionic, singularly positively charged arginium ions and doubly negatively charged adipate ions, with a 2:1 stoichiometry. One of the two crystallographically independent arginium ions in the L-arginine complex has a conformation hitherto unobserved in crystal structures containing the amino acid. In the present study the structural data on arginine complexes of saturated dicarboxylic acids with 0–5 C atoms separating the two carboxyl functions are given. In terms of molecular aggregation, formic and acetic acid comple

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Kolbe, Alfred, Carola Griehl, and Simone Biehler. "Molecular interactions in conjugates of dicarboxylic acids and amino acids." Journal of Molecular Structure 661-662 (December 2003): 239–46. http://dx.doi.org/10.1016/s0022-2860(03)00446-0.

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Teichman, Shlomit, and Baruch I. Kanner. "Aspartate-444 Is Essential for Productive Substrate Interactions in a Neuronal Glutamate Transporter." Journal of General Physiology 129, no. 6 (2007): 527–39. http://dx.doi.org/10.1085/jgp.200609707.

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In the central nervous system, electrogenic sodium- and potassium-coupled glutamate transporters terminate the synaptic actions of this neurotransmitter. In contrast to acidic amino acids, dicarboxylic acids are not recognized by glutamate transporters, but the related bacterial DctA transporters are capable of transporting succinate and other dicarboxylic acids. Transmembrane domain 8 contains several residues that differ between these two types of transporters. One of these, aspartate-444 of the neuronal glutamate transporter EAAC1, is conserved in glutamate transporters, but a serine residu

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Dissertations / Theses on the topic "Dicarboxylic Amino acids"

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Gaver, Charles Richard. "The highly preorganized ligands 8-(2-Pyridyl) Quinoline, 2,2'-dipyridyl amine and 1,10-phenanthroline-2, 9-dicarboxylic acid, and their complexing properties with metal ions." View electronic thesis, 2008. http://dl.uncw.edu/etd/2008-3/gaverc/charlesgaver.pdf.

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Hsieh, Yi-ching, and 謝宜妌. "Three-Dimensional Metal-organic Hybrid Materials of Metals with Dicarboxylic Acids: 2-Amino terephthalic Acid, Terephthalic Acid,Oxalic Acid and Thiophene-2,5-dicarboxylic Acid." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/67840538538135951390.

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碩士<br>國立中正大學<br>化學暨生物化學研究所<br>99<br>Using various dicarboxylates, namely 2-aminoterephthalate (N-BDC), terephthalate (BDC), Oxalate (Ox), thiophene-2,5-dicarboxylate (TDC), as bridging ligands to connect metal cations, led to the formation of a series of novel coordination polymers, which are {(Me2NH2)[In(TDC)2]•2(DMA)}n (1), {Ca2(TDC)2(DMA)2}n (2), {Nd2(BDC)3(DMA)2}n (3), {Na2Mn(TDC)2(DMF)2}n (4), {Yb3(NH2-BDC)4(NH3-BDC)(H2O)2．4DMA}n (5), {Mn(TDC)(DMA) }n (6), {(Me2NH2)[Sm(C2O4)(AcO)2] }n (7). Complex 1 is three-dimensional framework with two-fold interpenetration. Complexes 2, 3, 4, 5 , and

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Book chapters on the topic "Dicarboxylic Amino acids"

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Kretovich, W. L. "The Biosynthesis of Dicarboxylic Amino Acids and Enzymic Transformations of Amides in Plants." In Advances in Enzymology - and Related Areas of Molecular Biology. John Wiley & Sons, Inc., 2006. http://dx.doi.org/10.1002/9780470122655.ch10.

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Nagan, N., and H. M. Kagan. "Modulation of lysyl oxidase activity toward peptidyl lysine by vicinal dicarboxylic amino acid residues." In Biochemistry of Vitamin B6 and PQQ. Birkhäuser Basel, 1994. http://dx.doi.org/10.1007/978-3-0348-7393-2_44.

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Bowen, D. M., and S. L. Lowe. "Excitatory dicarboxylic amino acid and pyramidal neurone neurotransmission of the cerebral cortex in Alzheimer’s disease." In Key Topics in Brain Research. Springer Vienna, 1990. http://dx.doi.org/10.1007/978-3-7091-3396-5_28.

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Puiggalí, Jordi, Angélica Díaz, and Ramaz Katsarava. "Bio-based aliphatic polyesters from dicarboxylic acids and related sugar and amino acid derivatives." In Biodegradable and Biocompatible Polymer Composites. Elsevier, 2018. http://dx.doi.org/10.1016/b978-0-08-100970-3.00011-0.

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Lerma, J., A. V. Paternain, N. Salvador, F. Somohano, M. Morales,, and M. Casado. "Excitatory amino acid-activated channels." In Ion Channel Pharmacology. Oxford University PressOxford, 1998. http://dx.doi.org/10.1093/oso/9780198523604.003.0018.

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Abstract Besides the widespread metabolic function, it is now well established that the dicarboxylic amino acid glutamate plays a major role in excitatory synaptic transmission. Glutamate interacts with receptors forming cationic channels with different ion permeabilities, conductances, and activation-deactivation kinetics, as well as demonstrating distinct pharmacological properties.

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Conference papers on the topic "Dicarboxylic Amino acids"

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Garaeva, Svetlana, Galina Postolati, and Lilia Poleacova. "Rolul aminoacizilor liberi în funcționalitatea sanogenă a sistemului imunitar." In "Fiziologia şi sănătatea", congresul fiziologilor. Bulletin of the Academy of Sciences of Moldova. Medical Sciences, 2025. https://doi.org/10.52692/cfzl2024.22.

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The immune system, in connection with its functional tasks, is key in protecting the body from pathogenic external and internal factors. The formation of sanogenic homeostasis of the immune system depends on the intake of immunoactive amino acids into the body and the content in the blood, among which dicarboxylic amino acids are of greatest importance. An analysis of the literature allows us to conclude that the maintenance of sanogenic immunity is regulated by the level of intake of proteinogenic, primarily essential, amino acids into the body. The most significant for maintaining sanogenic

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Kostić, Marina, Vera Divac, and Sven Mangelinckx. "SYNTHESIS AND CHARACTERIZATION OF PALLADIUM (II)–2- (AZIDOMETHYL)CYCLOPROPANE-1,1-DICARBOXYLIC ACID COMPLEX." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.297k.

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The discovery that palladium complexes possess a wide range of biological activities (from antitumor, -viral, -malarial, -fungal to antimicrobial activities) encourages further research in this scientific field. Herein we describe the synthesis and characterization of a novel palladium (II) complex, using [Pd(dien)Cl]Cl and 2-(azidomethyl)cyclopropane-1,1-dicarboxylic acid (azmcpda) as a ligand. [Pd(dien)Cl]Cl was selected as a starting material taking into consideration its importance as a model for the investigation of the substitution reactions in coordination chemistry and a deeper underst

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Kostić, Marina D., Jovana S. Marjanović, Sven Mangelinckx, and Vera M. Divac. "In silico Drug-Likeness, Pharmacokinetic and other ADME properties of 2- (aminomethyl)cyclopropane-1,1-dicarboxylic acid." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.455k.

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Herein we present the results of in silico determination of Drug-Likeness, Pharmacokinetic and other ADME properties of 2-(aminomethyl)cyclopropane-1,1-dicarboxylic acid as an example constrained γ-amino dicarboxylic acid. The results of in silico screening of drug-likeness, pharmacokinetic and other ADME (absorption, distribution, metabolism and elimination) properties of 2-(aminomethyl)cyclopropane-1,1-dicarboxylic acid have revealed that this compound is not able to cross the blood-brain barrier, but it shows good solubility and gastrointestinal absorption. The possible target screening has

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Kostić, Marina, Vera M. Divac, Sven Mangelinckx, and Jovana S. Marjanović. "BSA binding of 2-(aminomethyl)cyclopropane-1,1-dicarboxylic acid." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.459k.

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Herein, we present the results of the study devoted to the exploration of BSA binding of 2-(aminomethyl)cyclopropane-1,1-dicarboxylic acid, as an example of constrained γ-amino dicarboxylic acid, and, taking into consideration that the effectiveness of a potential drug depends on its ability to bind to a protein carrier and in that way enable transfer through the blood stream. For the investigation of binding properties, we used the fluorescence emission titration of BSA with a synthesized compound. Considering that the BSA solution shows an intensive fluorescence emission around 360 nm, a dec

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Chen, Weilong, and Yan Bai. "FTIR Study of Chemical Modification of Tellurium Oxide Nanoparticles by Dicarboxyl Amino Acids." In 3rd International Conference on Material, Mechanical and Manufacturing Engineering (IC3ME 2015). Atlantis Press, 2015. http://dx.doi.org/10.2991/ic3me-15.2015.437.

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